GO:0009636

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Name response to toxin
Categary Process
Go Slim No
Go Link GO:0009636
Unique Molecular Interactions 2121
Total Molecular Interactions 2847
Total Single Events 32609
Pain Genes Associated 121

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to toxin. They are ordered first by their pain relevance and then by number of times they were reported for response to toxin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
2 INT227157 Binding of PEBP1 and Gpm6a 1 0.00 1.28 5.52
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49
5 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
6 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
7 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
8 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
9 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
10 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
11 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
12 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
13 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
14 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
15 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
16 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
17 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
18 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
19 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
20 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 0.69 0.5 2.18
21 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
22 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98
23 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
24 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
25 INT69556 Slc7a11 Regulation of Cpe 2 0.06 0.46 1.95
26 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
27 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
28 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8
29 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76
30 INT253895 Binding of Htr1b and Htr1d 1 0.40 0.52 1.74
31 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
32 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
33 INT139190 Binding of Fadd and Fas 4 0.38 2.65 1.71
34 INT49083 Mbp Positive_regulation of Eae1 1 0.02 2.96 1.71
35 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
36 INT105917 Binding of SLC22A6 and SLC22A8 2 0.31 0.34 1.67
37 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
38 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
39 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54
40 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54
41 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
42 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
43 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
44 INT291583 GUCY2C Regulation of Pde5a 1 0.00 1.12 1.45
45 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
46 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44
47 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
48 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
49 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41
50 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41
51 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41
52 INT108583 Binding of Vip and Fos 1 0.36 0 1.39
53 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35
54 INT52568 HTR1D Regulation of Localization of Gh 2 0.20 0.16 1.34
55 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 0.12 0.16 1.34
56 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
57 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
58 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32
59 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
60 INT124925 Negative_regulation of Slc6a1 Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
61 INT158144 Binding of Gpx1 and Glyat 2 0.31 0 1.29
62 INT66428 Dcc Positive_regulation of Fos 2 0.05 0.39 1.29
63 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
64 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
65 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
66 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
67 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
68 INT169768 Binding of Slc6a4 and Mir16-1 1 0.33 0 1.25
69 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
70 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
71 INT71443 CSAD Positive_regulation of Gene_expression of Fos 1 0.58 0.81 1.23
72 INT45891 Tyms Positive_regulation of Localization of Acot1 1 0.02 0 1.23
73 INT139191 Binding of Fas and RFFL 1 0.00 0.61 1.22
74 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22
75 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
76 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
77 INT109380 Binding of Adarb1 and Fos 1 0.02 0.38 1.19
78 INT139736 Htr1a Positive_regulation of Mapk3 1 0.54 0.13 1.19
79 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
80 INT73075 Adarb1 Regulation of Fos 1 0.01 0.07 1.18
81 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17
82 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
83 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 0.34 0.14 1.16
84 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
85 INT139188 Binding of Daxx and Fas 1 0.03 0.55 1.14
86 INT123454 CNR1 Regulation of Fos 1 0.00 0.06 1.12
87 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
88 INT123455 CNR1 Regulation of Positive_regulation of Fos 1 0.00 0.06 1.12
89 INT143941 Il1f5 Negative_regulation of Gene_expression of Fos 1 0.00 1.03 1.11
90 INT102421 POMC Regulation of Gene_expression of Fos 1 0.12 0.34 1.11
91 INT164378 MAPK3 Positive_regulation of Transcription of PDYN 1 0.50 0.2 1.09
92 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
93 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
94 INT132701 Adarb1 Negative_regulation of Gene_expression of Fos 1 0.01 0.73 1.07
95 INT100564 CRX Positive_regulation of Fos 1 0.04 0.89 1.06
96 INT50889 Binding of HTR1A and HTR1D 2 0.40 0.31 1.05
97 INT214875 Ap3d1 Negative_regulation of Gene_expression of Fos 1 0.00 0.39 1.04
98 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
99 INT146518 Tmem132a Positive_regulation of Gene_expression of Fos 1 0.68 0.06 1.04
100 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
101 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03
102 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
103 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03
104 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
105 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
106 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
107 INT143177 Apcs Negative_regulation of Gene_expression of Fos 1 0.02 0.36 1.01
108 INT11251 Negative_regulation of Cck Positive_regulation of Fos 2 0.48 0 1
109 INT21332 Binding of Drd2 and Gm5195 1 0.01 0.26 1
110 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99
111 INT71319 Binding of Penk and Fos 3 0.40 0.15 0.99
112 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
113 INT124918 Binding of PLEK and Maob 1 0.10 1.05 0.98
114 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
115 INT94206 SP5 Regulation of Gene_expression of FOS 1 0.22 0.7 0.98
116 INT281375 Il1r1 Negative_regulation of Gene_expression of Fos 1 0.47 0.61 0.97
117 INT133617 Fas Positive_regulation of Fadd 1 0.48 0.07 0.96
118 INT281380 Fos Negative_regulation of Gene_expression of FSCN1 1 0.07 0.4 0.96
119 INT155044 Negative_regulation of Ceacam3 Negative_regulation of Gene_expression of Fos 1 0.61 0 0.95
120 INT42482 Binding of Cpe and Pebp1 1 0.02 0 0.95
121 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
122 INT155043 Vta1 Regulation of Gene_expression of Fos 1 0.08 0 0.95
123 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
124 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
125 INT60827 Ddc Positive_regulation of Localization of Abat 1 0.12 0.34 0.94
126 INT80601 Akr1d1 Regulation of Positive_regulation of Fos 1 0.06 0 0.94
127 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94
128 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
129 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94
130 INT48148 Fos Positive_regulation of Gene_expression of Pdyn 1 0.21 0 0.94
131 INT186568 Hpcl1 Regulation of Gene_expression of Fos 1 0.22 0.07 0.94
132 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
133 INT281377 FSCN1 Positive_regulation of Gene_expression of Fos 1 0.08 0.49 0.93
134 INT89514 Pnoc Regulation of Gene_expression of Fos 1 0.47 0.98 0.93
135 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
136 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93
137 INT223871 Ltp Positive_regulation of Gene_expression of Mapk1 1 0.33 0 0.93
138 INT143578 Olr404 Negative_regulation of Positive_regulation of Fos 1 0.01 0.39 0.93
139 INT60828 Ddc Positive_regulation of Abat 1 0.13 0.34 0.93
140 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93
141 INT34837 Maob Regulation of Negative_regulation of Mme 1 0.48 0.15 0.92
142 INT86350 Negative_regulation of Adarb1 Negative_regulation of Positive_regulation of Fos 1 0.04 0.8 0.92
143 INT86349 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Fos 1 0.42 0.8 0.92
144 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91
145 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
146 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
147 INT90561 Slc6a1 Negative_regulation of Abat 1 0.02 0.25 0.91
148 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91
149 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
150 INT66536 Il1a Regulation of Gene_expression of Fos 1 0.59 0 0.91
151 INT333303 Zic2 Regulation of Gene_expression of Slc6a4 1 0.60 0.47 0.91
152 INT166221 Negative_regulation of Gls Negative_regulation of Gene_expression of Fos 1 0.50 0.37 0.9
153 INT281089 Binding of Gria1 and Ltp 1 0.25 0.6 0.9
154 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
155 INT164677 Ngf Positive_regulation of Gene_expression of Fos 1 0.52 0.08 0.89
156 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
157 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
158 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
159 INT97738 Mdk Positive_regulation of Mapk3 1 0.08 0.66 0.87
160 INT272039 Ddc Positive_regulation of Gene_expression of Aanat 1 0.00 0.26 0.87
161 INT73653 Binding of Creb1 and Fos 1 0.40 1.49 0.87
162 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
163 INT97735 Trib3 Positive_regulation of Mapk3 1 0.05 0.66 0.87
164 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86
165 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
166 INT311612 Binding of Drd2 and Sert1 1 0.12 0.65 0.86
167 INT130769 FASLG Negative_regulation of Binding of FAS 1 0.10 0.66 0.86
168 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
169 INT124878 Gnat3 Negative_regulation of Gene_expression of FOS 1 0.09 0.16 0.85
170 INT196578 Ephb1 Positive_regulation of Phosphorylation of Mapk9 1 0.13 0.5 0.85
171 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85
172 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85
173 INT140447 Ngf Regulation of Scn9a 1 0.69 0.16 0.84
174 INT122833 AP1B1 Regulation of Gene_expression of Fos 1 0.16 0 0.83
175 INT127545 Gria1 Positive_regulation of Gene_expression of Gnptab 1 0.00 0.7 0.83
176 INT108072 Grip2 Positive_regulation of Gene_expression of Fos 1 0.08 0.21 0.82
177 INT329278 Vta1 Positive_regulation of Gene_expression of Fos 1 0.22 0 0.82
178 INT186567 Negative_regulation of Hpcl1 Positive_regulation of Fos 1 0.11 0.07 0.82
179 INT124877 Gnat3 Negative_regulation of FOS 1 0.09 0.15 0.82
180 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
181 INT124876 Gnat3 Negative_regulation of Positive_regulation of FOS 1 0.09 0.15 0.82
182 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81
183 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
184 INT164607 Positive_regulation of GSR Positive_regulation of Gpx1 1 0.01 0.33 0.81
185 INT123492 TIAF1 Positive_regulation of Gene_expression of CCL4 1 0.00 1.45 0.81
186 INT164606 GSR Positive_regulation of Gpx1 1 0.01 0.32 0.8
187 INT341367 CRX Positive_regulation of Positive_regulation of FOS 1 0.04 0.83 0.8
188 INT161520 H2-M3 Regulation of Positive_regulation of Mapk1 1 0.09 0.47 0.79
189 INT111129 Adarb1 Regulation of Gene_expression of Fos 1 0.09 0 0.79
190 INT132977 Tac1 Positive_regulation of Mapk1 1 0.06 0.17 0.79
191 INT117909 Mastl Positive_regulation of Mapk1 1 0.04 0 0.79
192 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78
193 INT164364 Binding of DRD2 and SUGT1 2 0.06 0.33 0.77
194 INT152857 PRS Regulation of Nefl 1 0.00 0.19 0.77
195 INT152833 Nefl Regulation of Prkcg 1 0.12 0.19 0.77
196 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
197 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
198 INT166222 Gene_expression of Fos Positive_regulation of Col6a6 1 0.01 0.57 0.77
199 INT232621 Binding of Gria1 and Psd 1 0.10 0.29 0.77
200 INT152834 Nefl Regulation of Nefh 1 0.10 0.19 0.77

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to toxin. They are ordered first by their pain relevance and then by number of times they were reported in response to toxin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
3 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
4 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
5 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
6 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
7 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
8 INT5587 Regulation of Fos 191 0.62 40.81 99.7
9 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
10 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
11 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
12 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
13 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
14 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
15 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
16 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
17 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
18 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
19 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
20 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
21 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
22 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
23 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
24 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
25 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
26 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
27 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
28 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
29 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92
30 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
31 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05
32 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
33 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
34 INT6053 Transcription of Fos 107 0.72 20.97 31.88
35 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
36 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
37 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
38 INT6058 Localization of Fos 73 0.81 16.7 30.84
39 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
40 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27
41 INT67 Negative_regulation of Ddc 66 0.59 15.34 28.96
42 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23
43 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
44 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
45 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84
46 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
47 INT6594 Gene_expression of HTR1D 60 0.75 10.15 27.13
48 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95
49 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
50 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
51 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
52 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01
53 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
54 INT12484 Binding of Drd2 45 0.48 15.17 24.72
55 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
56 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
57 INT134651 Binding of TLR4 89 0.48 66.96 23.19
58 INT9282 Gene_expression of HTR1B 48 0.75 12.15 22.94
59 INT6270 Binding of HTR1D 55 0.47 9.54 22.86
60 INT76249 Gene_expression of Gria1 67 0.75 15.07 22.78
61 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05
62 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
63 INT5586 Binding of Fos 47 0.48 12.7 21.33
64 INT129987 Phosphorylation of Gria1 63 0.80 20.65 21.02
65 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94
66 INT6230 Localization of Ddc 40 0.79 13.11 20.88
67 INT49774 Binding of DRD2 48 0.48 17.42 20.73
68 INT78901 Localization of CCL5 67 0.78 40.79 20.59
69 INT9782 Binding of HTR1B 43 0.47 12.08 19.83
70 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01
71 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
72 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
73 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
74 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
75 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
76 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01
77 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88
78 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
79 INT9358 Positive_regulation of HTR1B 26 0.67 11 17.51
80 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
81 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
82 INT7580 Positive_regulation of Mbp 54 0.70 23.37 17.14
83 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07
84 INT77620 Gene_expression of Fas 146 0.78 72.4 16.61
85 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31
86 INT14887 Gene_expression of Mbp 55 0.75 36.13 16.11
87 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59
88 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
89 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
90 INT128401 Positive_regulation of Positive_regulation of Mapk1 39 0.70 10.88 15.38
91 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36
92 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
93 INT5430 Gene_expression of Scn8a 37 0.75 4.58 14.82
94 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
95 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
96 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
97 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
98 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
99 INT111529 Phosphorylation of Mapk3 41 0.80 21.14 13.72
100 INT49538 Binding of Gria1 22 0.47 2.66 13.35
101 INT5599 Regulation of Drd2 25 0.52 3.07 13.31
102 INT7465 Negative_regulation of Mbp 53 0.58 19.12 13.27
103 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
104 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15
105 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94
106 INT15246 Regulation of FOS 32 0.60 15.34 12.94
107 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
108 INT48927 Regulation of Mapk3 25 0.60 14.06 12.82
109 INT635 Negative_regulation of MAOB 51 0.59 24.5 12.66
110 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37
111 INT100096 Regulation of Slc6a4 24 0.62 7.25 12.28
112 INT119396 Regulation of Positive_regulation of Mapk1 22 0.61 7.88 12.25
113 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23
114 INT111948 Positive_regulation of Gria1 23 0.61 7.55 12.03
115 INT114674 Gene_expression of Mdm2 15 0.78 3.51 11.85
116 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77
117 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
118 INT6051 Positive_regulation of Transcription of Fos 27 0.69 6.3 11.48
119 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
120 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
121 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83
122 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8
123 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
124 INT128364 Positive_regulation of Ccl3 20 0.70 23.96 10.65
125 INT52657 Phosphorylation of Fos 20 0.80 6.36 10.64
126 INT66303 Regulation of Slc6a4 10 0.45 4.82 10.55
127 INT48921 Regulation of Mapk1 25 0.49 19.51 10.41
128 INT87451 Positive_regulation of Mapk3 34 0.67 12.82 10.38
129 INT9027 Positive_regulation of Ddc 24 0.66 6.04 10.19
130 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
131 INT17592 Positive_regulation of Regulation of Fos 21 0.67 3.54 10.07
132 INT8072 Localization of Gria1 17 0.75 2.62 10.04
133 INT88020 Positive_regulation of Fas 32 0.70 19.78 9.97
134 INT96298 Negative_regulation of Gria1 25 0.57 10.61 9.7
135 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
136 INT53062 Gene_expression of Ddc 31 0.77 11.59 9.63
137 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
138 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
139 INT17764 Negative_regulation of Drd2 17 0.42 4.63 9.46
140 INT47744 Binding of Slc6a4 21 0.48 5.52 9.45
141 INT4929 Binding of Mbp 25 0.48 18.01 9.41
142 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4
143 INT1218 Negative_regulation of Maob 24 0.59 9.76 9.39
144 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
145 INT73596 Positive_regulation of Gene_expression of BAX 43 0.67 40.97 9.22
146 INT155808 Gene_expression of Ccl4 24 0.65 21.36 9.18
147 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
148 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14
149 INT13296 Transcription of Drd2 17 0.66 2.7 9.07
150 INT109432 Negative_regulation of Phosphorylation of Mapk1 19 0.54 7.01 8.98
151 INT111133 Negative_regulation of Mapk3 31 0.57 10.89 8.9
152 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83
153 INT6682 Regulation of Gene_expression of Drd2 13 0.51 2.17 8.82
154 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
155 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
156 INT220 Negative_regulation of Ddc 16 0.59 2.94 8.66
157 INT91337 Gene_expression of CCL4 29 0.75 16.23 8.64
158 INT70848 Gene_expression of Casp1 24 0.77 10.97 8.52
159 INT80034 Positive_regulation of Gene_expression of FAS 32 0.67 30.34 8.51
160 INT17333 Positive_regulation of Positive_regulation of FOS 17 0.67 6.06 8.4
161 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
162 INT126848 Positive_regulation of Phosphorylation of Mapk1 30 0.50 15.94 8.34
163 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
164 INT71785 Gene_expression of MAPK3 22 0.75 11.35 8.21
165 INT56580 Positive_regulation of Htr1b 16 0.67 2.95 7.97
166 INT13041 Binding of Htr1b 14 0.47 4.92 7.95
167 INT95317 Positive_regulation of Slc6a1 6 0.69 5.91 7.94
168 INT82762 Positive_regulation of Positive_regulation of Mapk3 23 0.67 7.72 7.91
169 INT114675 Positive_regulation of Gene_expression of Mdm2 1 0.70 1.98 7.9
170 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
171 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82
172 INT78226 Gene_expression of Mbp 43 0.75 22.14 7.79
173 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77
174 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
175 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
176 INT72372 Positive_regulation of Phosphorylation of Mapk3 30 0.67 13.6 7.69
177 INT91618 Positive_regulation of Phosphorylation of MAPK3 21 0.67 7.99 7.65
178 INT47848 Negative_regulation of Positive_regulation of FOS 14 0.57 3.78 7.63
179 INT18190 Regulation of DRD2 11 0.60 9.01 7.63
180 INT47811 Positive_regulation of Localization of Ddc 11 0.69 4 7.6
181 INT54363 Gene_expression of Htr1d 13 0.75 3.8 7.59
182 INT6307 Positive_regulation of HTR1D 17 0.67 3.11 7.51
183 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
184 INT88014 Positive_regulation of Gene_expression of Fas 29 0.50 14.84 7.47
185 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
186 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39
187 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
188 INT105528 Negative_regulation of Slc6a1 7 0.57 2.79 7.32
189 INT4284 Regulation of Ddc 17 0.43 8.17 7.31
190 INT6892 Regulation of Htr1b 9 0.60 1.32 7.24
191 INT85764 Binding of PEBP1 9 0.44 4.52 7.2
192 INT57023 Negative_regulation of Gene_expression of Gria1 20 0.58 6.92 7.17
193 INT25772 Regulation of HTR1B 15 0.60 3.8 7.17
194 INT15553 Negative_regulation of Htr1b 13 0.41 2.61 7.16
195 INT153271 Localization of Ccl3 7 0.81 11.29 7.14
196 INT119651 Binding of Slc6a4 12 0.32 4.65 7.07
197 INT60196 Binding of FOS 33 0.47 13.11 6.95
198 INT139149 Binding of Gria1 22 0.37 5.71 6.88
199 INT112211 Gene_expression of Slc6a1 8 0.78 4.48 6.86
200 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
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