GO:0009749

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Name response to glucose stimulus
Categary Process
Go Slim No
Go Link GO:0009749
Unique Molecular Interactions 1374
Total Molecular Interactions 1799
Total Single Events 16781
Pain Genes Associated 104

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to glucose stimulus. They are ordered first by their pain relevance and then by number of times they were reported for response to glucose stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22
2 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44
3 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
4 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
5 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39
6 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29
7 INT259209 Binding of Glul and Flna 1 0.03 0 4.2
8 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
9 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
10 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
11 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
12 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
13 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
14 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
15 INT26677 Penk Regulation of Localization of Trh 5 0.50 0 3.05
16 INT137230 Trh Regulation of Gene_expression of Oprd1 1 0.01 1.62 2.75
17 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
18 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
19 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
20 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
21 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25
22 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
23 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
24 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
25 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
26 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
27 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
28 INT26676 Pomc Regulation of Localization of Trh 3 0.14 0 1.73
29 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
30 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
31 INT32839 Binding of Trh and Penk 2 0.42 0 1.63
32 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
33 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
34 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
35 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
36 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
37 INT33988 TRH Regulation of Localization of IGKV1D-39 1 0.12 0.47 1.35
38 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
39 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
40 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
41 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
42 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
43 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
44 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
45 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
46 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2
47 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
48 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
49 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
50 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
51 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18
52 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18
53 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
54 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
55 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 0.15 1.14 1.13
56 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 0.20 1.14 1.13
57 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12
58 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
59 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
60 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
61 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
62 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
63 INT25036 TRH Regulation of Prl 4 0.27 1.75 1.09
64 INT7927 Penk Regulation of Trh 2 0.26 0.66 1.09
65 INT283934 Phax Negative_regulation of Positive_regulation of Mapk14 1 0.03 2.06 1.09
66 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
67 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08
68 INT17414 TRH Positive_regulation of Prl 4 0.47 0 1.07
69 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
70 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
71 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07
72 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
73 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06
74 INT57509 Trh Negative_regulation of Adarb1 1 0.02 0.22 1.05
75 INT154846 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Trpv1 1 0.23 0.07 1.05
76 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
77 INT352456 Dusp1 Negative_regulation of Mapk14 1 0.03 1.31 1.03
78 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
79 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
80 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
81 INT25155 TRH Positive_regulation of PRL 2 0.50 0.4 1
82 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99
83 INT69307 Prkcq Negative_regulation of TH1L 1 0.00 0.98 0.98
84 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
85 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
86 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
87 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95
88 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
89 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
90 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93
91 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
92 INT318461 Nnat Positive_regulation of Mapk14 1 0.05 0.97 0.92
93 INT262165 Nr0b2 Negative_regulation of Nr5a2 1 0.02 0.5 0.92
94 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
95 INT352465 Dusp1 Negative_regulation of Gene_expression of Mapk14 1 0.03 1.09 0.92
96 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
97 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91
98 INT32840 Regulation of Binding of Trh and Penk 1 0.26 0 0.91
99 INT352444 Dusp1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.09 0.91
100 INT75920 Slc8a1 Negative_regulation of Cpox 1 0.03 0.85 0.89
101 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
102 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
103 INT318462 Nnat Positive_regulation of Nfkb1 1 0.46 0.9 0.88
104 INT168019 Ldha Regulation of Gpt 1 0.01 0.15 0.88
105 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
106 INT168018 Positive_regulation of Ldha Regulation of Gpt 1 0.01 0.15 0.88
107 INT17416 TRH Positive_regulation of Localization of Prl 1 0.47 0 0.85
108 INT307045 Tmie Negative_regulation of Positive_regulation of Casp3 1 0.01 0.29 0.85
109 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
110 INT115655 Glp1r Positive_regulation of Ins1 1 0.42 0 0.84
111 INT84102 B3GAT1 Positive_regulation of Localization of Glp1r 1 0.09 0 0.83
112 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82
113 INT128590 Mapk14 Regulation of Nav1 1 0.21 0.25 0.82
114 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
115 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
116 INT7926 Regulation of Penk Regulation of Trh 1 0.26 0.66 0.8
117 INT56499 Neurod1 Positive_regulation of Maoa 1 0.47 0 0.8
118 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
119 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
120 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
121 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
122 INT52561 Trh Positive_regulation of Localization of Lhb 1 0.01 0.14 0.77
123 INT196575 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1a 1 0.04 0.44 0.77
124 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
125 INT18402 Glp1r Regulation of Localization of Sst 1 0.19 0 0.77
126 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
127 INT49585 Binding of Glul and Selenbp2 1 0.20 0.19 0.76
128 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
129 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
130 INT3570 Trh Regulation of Localization of Gnrhr 2 0.26 0.3 0.75
131 INT91655 SLC8A1 Negative_regulation of CASP1 1 0.02 0.43 0.75
132 INT307044 Tmie Regulation of Casp3 1 0.01 0 0.75
133 INT111194 Binding of NEUROD1 and Pck1 1 0.39 0 0.75
134 INT196799 Prkaca Positive_regulation of Phosphorylation of Trh 1 0.02 0 0.74
135 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74
136 INT41919 Binding of Tacr1 and Trh 1 0.06 0 0.74
137 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
138 INT114860 Negative_regulation of Insrr Positive_regulation of Casp3 1 0.02 0.71 0.73
139 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
140 INT43717 Positive_regulation of Binding of Trh and Penk 1 0.56 0 0.72
141 INT34823 Regulation of Binding of Ldha and Akr7a3 1 0.43 0.28 0.72
142 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
143 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
144 INT34824 Binding of Ldha and Akr7a3 1 0.36 0.28 0.71
145 INT81769 Binding of Chrna4 and Neurod1 1 0.35 0.07 0.69
146 INT134029 Olr696 Regulation of Ldha 1 0.00 0.15 0.68
147 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
148 INT164783 Positive_regulation of Mapk14 Regulation of Gene_expression of Cx3cr1 1 0.19 0.81 0.68
149 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
150 INT155457 Tnfrsf1a Positive_regulation of Mapk14 1 0.20 1.17 0.67
151 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
152 INT94241 Binding of Cp and Slc2a2 1 0.13 0.81 0.67
153 INT92026 Egr1 Positive_regulation of Fos 1 0.50 0.61 0.67
154 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
155 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
156 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65
157 INT40763 Trh Negative_regulation of Penk 1 0.19 0 0.65
158 INT50634 Ddc Regulation of Gene_expression of Glul 1 0.02 0 0.65
159 INT107330 Binding of Adarb1 and Trh 1 0.01 0 0.65
160 INT40762 Trh Negative_regulation of Prss12 1 0.06 0 0.65
161 INT76877 Binding of Slc3a1 and Slc8a1 1 0.02 0 0.64
162 INT312106 EGR1 Regulation of Gene_expression of PTGES 1 0.31 1.06 0.64
163 INT351445 Binding of Vta1 and Positive_regulation of Casp3 1 0.01 0.39 0.64
164 INT106754 Pes1 Positive_regulation of Casp3 1 0.13 0 0.63
165 INT154263 NEUROD1 Positive_regulation of Gene_expression of GAL 1 0.50 0.06 0.63
166 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
167 INT6465 Trh Regulation of Negative_regulation of Npr1 1 0.01 0 0.63
168 INT223155 Binding of Mapk14 and Stat4 1 0.36 0.84 0.63
169 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
170 INT106752 Negative_regulation of Pes1 Positive_regulation of Casp3 1 0.12 0 0.63
171 INT3617 Trh Regulation of Localization of Gh1 3 0.65 0.55 0.62
172 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
173 INT9163 Tnf Regulation of Gene_expression of Glul 1 0.12 1.99 0.62
174 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
175 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
176 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
177 INT36320 PDYN Negative_regulation of Ctsb 1 0.00 0 0.61
178 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 0.11 0 0.61
179 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
180 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
181 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
182 INT128811 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Casp1 1 0.06 0.35 0.61
183 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61
184 INT21607 ACE Positive_regulation of ANGPT2 1 0.03 0.13 0.61
185 INT114505 Negative_regulation of Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
186 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6
187 INT114506 Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
188 INT133320 Penk Negative_regulation of Gene_expression of Casp3 1 0.11 0.91 0.6
189 INT83424 Binding of CD40LG and ADIPOQ 2 0.13 1 0.59
190 INT83426 ADIPOQ Negative_regulation of Binding of CD40LG 2 0.21 1 0.59
191 INT163376 RYBP Positive_regulation of Gene_expression of Casp3 2 0.01 0.57 0.59
192 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
193 INT223158 Mapk3 Regulation of Gene_expression of Mapk14 1 0.48 1.33 0.59
194 INT40153 Gnrh1 Regulation of Trh 1 0.47 0 0.59
195 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
196 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
197 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
198 INT25156 TRH Regulation of PRL 2 0.27 0.81 0.56
199 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
200 INT196585 Mapk14 Regulation of TNF 1 0.02 0.36 0.55

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to glucose stimulus. They are ordered first by their pain relevance and then by number of times they were reported in response to glucose stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
2 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
3 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
4 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
5 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
6 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
7 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
8 INT339 Regulation of Trh 156 0.62 39.27 83.55
9 INT403 Localization of Trh 241 0.81 28.55 81.45
10 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
11 INT1376 Binding of Trh 121 0.48 20 69.86
12 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83
13 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
14 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
15 INT3920 Localization of Ldha 241 0.81 83.08 58.72
16 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
17 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
18 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
19 INT2323 Gene_expression of Trh 146 0.78 29.92 49.5
20 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
21 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43
22 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
23 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
24 INT989 Negative_regulation of Trh 90 0.59 15.45 43.63
25 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81
26 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
27 INT8691 Localization of Insr 85 0.80 9.27 30.32
28 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
29 INT5300 Regulation of Insr 54 0.60 11.33 29.26
30 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
31 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
32 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
33 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95
34 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71
35 INT18400 Localization of Glp1r 97 0.80 11.96 24.32
36 INT9155 Gene_expression of Glul 60 0.77 17.97 23.95
37 INT61665 Phosphorylation of Trh 53 0.79 2.26 23.9
38 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
39 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16
40 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
41 INT4369 Gene_expression of Ldha 157 0.76 88.12 22.45
42 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
43 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
44 INT1327 Regulation of Localization of Trh 45 0.62 6.05 22.09
45 INT2911 Positive_regulation of Glul 36 0.70 11.09 22.07
46 INT168482 Gene_expression of Nnat 45 0.77 24.01 21.53
47 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98
48 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
49 INT1278 Negative_regulation of Ldha 93 0.59 37.66 19.36
50 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
51 INT14419 Negative_regulation of Localization of Trh 40 0.59 2.04 17.42
52 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
53 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
54 INT13209 Regulation of Binding of Trh 19 0.62 2.84 16.26
55 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16
56 INT4340 Positive_regulation of Localization of Ldha 46 0.70 14.52 15.66
57 INT24798 Negative_regulation of Glul 52 0.55 27.25 15.17
58 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
59 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
60 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
61 INT57878 Positive_regulation of Gene_expression of Egr1 36 0.70 20.42 14.45
62 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
63 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52
64 INT104954 Negative_regulation of Positive_regulation of Mapk14 29 0.58 17.71 13.31
65 INT12191 Negative_regulation of Localization of Ldha 35 0.59 13.71 12.35
66 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23
67 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18
68 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
69 INT118906 Regulation of Mapk14 21 0.44 17.95 11.63
70 INT373 Regulation of Ldha 37 0.61 17.86 11.41
71 INT23825 Negative_regulation of Binding of Trh 17 0.59 1.62 11.24
72 INT987 Localization of TRH 37 0.78 10.53 11.1
73 INT10009 Positive_regulation of TRH 31 0.67 8.94 11.03
74 INT3637 Positive_regulation of Localization of Trh 33 0.70 2.13 10.55
75 INT143964 Positive_regulation of Phosphorylation of Trh 10 0.20 0.1 10.54
76 INT78695 Regulation of Casp3 24 0.44 9.43 10.48
77 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
78 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
79 INT49660 Positive_regulation of EGR1 54 0.69 32.17 9.89
80 INT75919 Gene_expression of Slc8a1 23 0.63 16.44 9.84
81 INT57876 Positive_regulation of Egr1 46 0.70 25.6 9.41
82 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22
83 INT73021 Gene_expression of EGR1 43 0.77 24.65 9.18
84 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
85 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89
86 INT3622 Regulation of CTSB 34 0.58 16.08 8.76
87 INT892 Regulation of TRH 23 0.60 8.46 8.54
88 INT318459 Positive_regulation of Gene_expression of Nnat 1 0.60 9.92 8.49
89 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2
90 INT45234 Binding of Ldha 20 0.37 9.8 8.18
91 INT15459 Gene_expression of TRH 17 0.78 4.89 8.17
92 INT24799 Regulation of Glul 22 0.45 8.3 8
93 INT2257 Localization of Gip 31 0.74 11.08 7.92
94 INT159750 Negative_regulation of Gene_expression of Mapk14 15 0.40 10.88 7.81
95 INT98178 Localization of Casp3 32 0.65 21.01 7.77
96 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
97 INT9932 Positive_regulation of Positive_regulation of Trh 13 0.50 1.8 7.63
98 INT7168 Positive_regulation of Ctsb 9 0.70 0.3 7.58
99 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
100 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
101 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
102 INT128695 Regulation of Gene_expression of Mapk14 14 0.44 11.49 7.14
103 INT64370 Gene_expression of Neurod1 22 0.75 5.19 7.1
104 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
105 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
106 INT47944 Positive_regulation of Localization of Glp1r 23 0.70 0.16 6.79
107 INT19146 Negative_regulation of Apoa2 19 0.36 5.34 6.73
108 INT50633 Regulation of Gene_expression of Glul 12 0.60 1.64 6.59
109 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51
110 INT73022 Positive_regulation of Gene_expression of EGR1 21 0.69 10.61 6.5
111 INT47942 Positive_regulation of Glp1r 38 0.70 15.94 6.47
112 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
113 INT7923 Transcription of Trh 14 0.72 4.44 6.32
114 INT6097 Negative_regulation of NEUROD1 30 0.57 9.71 6.24
115 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
116 INT57232 Binding of Casp3 22 0.36 9.42 6.2
117 INT72110 Gene_expression of Glp1r 48 0.78 22.46 6.17
118 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
119 INT128587 Localization of Mapk14 15 0.81 8.41 6.1
120 INT6098 Binding of NEUROD1 17 0.47 3.4 5.99
121 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
122 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
123 INT34440 Negative_regulation of Positive_regulation of Trh 12 0.59 0 5.7
124 INT4034 Negative_regulation of Gip 16 0.53 6.46 5.65
125 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
126 INT168483 Regulation of Gene_expression of Nnat 3 0.61 5.93 5.5
127 INT85789 Gene_expression of Prlh 10 0.78 4.5 5.47
128 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
129 INT48840 Gene_expression of Nkx2-2 8 0.23 1.55 5.44
130 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36
131 INT39900 Positive_regulation of Gene_expression of Ldha 36 0.50 20.35 5.22
132 INT50105 Localization of CTSB 29 0.78 10.98 5.21
133 INT10078 Positive_regulation of Gene_expression of Trh 17 0.50 4.23 5.19
134 INT47704 Regulation of Egr1 17 0.60 2.43 5.18
135 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
136 INT47706 Negative_regulation of Positive_regulation of Egr1 9 0.41 6.11 5.1
137 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
138 INT126047 Regulation of Phosphorylation of Mapk14 7 0.60 5.05 5.03
139 INT75645 Binding of EIF2B3 10 0.07 0.21 4.9
140 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
141 INT57376 Transcription of EGR1 20 0.69 12.94 4.84
142 INT171472 Binding of Mapk14 10 0.36 6.79 4.83
143 INT58766 Gene_expression of ANGPT2 41 0.67 21.65 4.82
144 INT7170 Positive_regulation of Positive_regulation of Ctsb 1 0.40 0 4.76
145 INT51944 Positive_regulation of Transcription of Egr1 12 0.49 1.96 4.72
146 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
147 INT25146 Negative_regulation of Positive_regulation of Glul 5 0.43 0.91 4.53
148 INT2213 Regulation of EP300 10 0.54 4.72 4.5
149 INT117936 Regulation of Gene_expression of Egr1 18 0.60 9.37 4.45
150 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
151 INT50631 Positive_regulation of Gene_expression of Glul 9 0.43 3 4.37
152 INT37379 Regulation of Localization of Glp1r 10 0.62 0.16 4.32
153 INT57642 Gene_expression of PCSK1 26 0.76 5.09 4.28
154 INT5015 Regulation of Gene_expression of Trh 9 0.62 6.47 4.25
155 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
156 INT51084 Binding of Insr 13 0.30 4.25 4.23
157 INT15257 Positive_regulation of Nkx2-2 10 0.21 1.75 4.2
158 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
159 INT33229 Gene_expression of Bad 9 0.70 6.95 4.15
160 INT51180 Regulation of Nkx2-2 5 0.26 2.16 4.14
161 INT83035 Binding of INSR 16 0.47 9.29 4.11
162 INT2453 Positive_regulation of Apoa2 20 0.54 3.49 4.08
163 INT50646 Transcription of Glul 12 0.38 3.59 4.07
164 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
165 INT131782 Regulation of Positive_regulation of Mapk14 7 0.43 2.68 4.02
166 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
167 INT276198 Positive_regulation of Pten 1 0.52 5.02 3.88
168 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
169 INT8600 Binding of Nkx2-2 6 0.10 0.87 3.82
170 INT54886 Negative_regulation of ANGPT2 25 0.42 9.33 3.79
171 INT123502 Binding of Egr1 11 0.35 6.7 3.77
172 INT117773 Positive_regulation of Phosphorylation of Ptk2 9 0.69 0.89 3.71
173 INT17379 Positive_regulation of Prlh 6 0.64 0.58 3.68
174 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67
175 INT2258 Positive_regulation of Gip 16 0.60 5.51 3.67
176 INT34822 Regulation of Localization of Ldha 12 0.57 4.03 3.65
177 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
178 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58
179 INT8781 Regulation of Prlh 6 0.45 0.67 3.58
180 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
181 INT20011 Regulation of NEUROD1 10 0.44 3.83 3.53
182 INT50648 Negative_regulation of Gene_expression of Glul 9 0.58 2.7 3.53
183 INT20265 Gene_expression of Ctsb 3 0.47 1.01 3.52
184 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
185 INT10116 Localization of INSR 11 0.57 5.43 3.48
186 INT66570 Localization of Glul 4 0.78 0.37 3.45
187 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44
188 INT122997 Phosphorylation of Rps6kb1 46 0.72 9.92 3.43
189 INT949 Negative_regulation of TRH 12 0.43 3.06 3.4
190 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36
191 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
192 INT250581 Gene_expression of SELS 4 0.78 47.37 3.27
193 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
194 INT180250 Positive_regulation of GLUL 23 0.29 7.57 3.23
195 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
196 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1
197 INT137656 Negative_regulation of Binding of Casp3 4 0.21 0.7 3.09
198 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
199 INT21610 Positive_regulation of ANGPT2 23 0.41 13.28 3.03
200 INT4186 Negative_regulation of Localization of Gip 7 0.53 2.11 2.98
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