GO:0009790

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Name embryo development
Categary Process
Go Slim Yes
Go Link GO:0009790
Unique Molecular Interactions 1040
Total Molecular Interactions 1373
Total Single Events 10636
Pain Genes Associated 114

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for embryo development. They are ordered first by their pain relevance and then by number of times they were reported for embryo development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
2 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
3 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
4 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
5 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
6 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
7 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
8 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
9 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
10 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
11 INT93781 Racgap1 Positive_regulation of Positive_regulation of Gnptab 1 0.02 0.07 1.49
12 INT93782 Racgap1 Positive_regulation of Rgs9 1 0.55 0.07 1.49
13 INT93783 Racgap1 Positive_regulation of Gnptab 1 0.02 0.07 1.49
14 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
15 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
16 INT299311 Binding of RPTOR and RICTOR 1 0.38 0.21 1.4
17 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
18 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
19 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
20 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
21 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
22 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
23 INT70288 Negative_regulation of Atxn2l Positive_regulation of Racgap1 1 0.02 0.3 1.19
24 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
25 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
26 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
27 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
28 INT70289 Atxn2l Positive_regulation of Racgap1 1 0.04 0.29 1.15
29 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
30 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
31 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
32 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
33 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
34 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
35 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
36 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
37 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
38 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
39 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
40 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02
41 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
42 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
43 INT221747 Gtf3a Positive_regulation of Positive_regulation of Racgap1 1 0.00 0.33 1
44 INT61637 Binding of P2ry2 and Gtpbp4 1 0.02 0.1 0.99
45 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
46 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
47 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
48 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
49 INT149390 Foxm1 Positive_regulation of Trpa1 1 0.28 0.31 0.94
50 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
51 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 0.01 1.17 0.93
52 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
53 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 0.01 1.17 0.93
54 INT65462 Bri3 Negative_regulation of Racgap1 1 0.02 0.39 0.93
55 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
56 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
57 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
58 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
59 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92
60 INT13282 Fgf2 Regulation of Ngf 1 0.66 0.21 0.91
61 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
62 INT66334 Fgf2 Regulation of Fgf1 1 0.37 0.17 0.9
63 INT13280 Ngf Regulation of Fgf2 1 0.48 0.2 0.9
64 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9
65 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
66 INT59497 Adh1 Regulation of POMC 1 0.03 0 0.86
67 INT66333 Fgf2 Negative_regulation of Positive_regulation of Npy 1 0.20 0.17 0.85
68 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
69 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
70 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
71 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
72 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
73 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
74 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
75 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
76 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
77 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
78 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
79 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
80 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
81 INT296285 Binding of Car1 and Grin2b 1 0.14 0.32 0.72
82 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
83 INT296282 Grin2b Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
84 INT216654 Binding of P2ry2 and DRGX 1 0.01 1.59 0.71
85 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71
86 INT296298 Grin2b Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
87 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
88 INT98956 Positive_regulation of Binding of NR5A2 and SP1 1 0.00 0 0.7
89 INT98951 Positive_regulation of Binding of NR5A2 and SP3 1 0.00 0 0.7
90 INT98957 Binding of NR5A2 and SP3 1 0.00 0 0.7
91 INT98958 Binding of NR5A2 and SP1 1 0.00 0 0.7
92 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 0.12 0.19 0.69
93 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
94 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
95 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
96 INT152925 Aanat Positive_regulation of Nanog 1 0.02 0.42 0.67
97 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 0.18 0.07 0.66
98 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
99 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 0.18 0.07 0.66
100 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
101 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
102 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
103 INT135361 Prr14 Positive_regulation of Mecp2 1 0.24 0.15 0.64
104 INT216644 Binding of P2ry1 and P2ry2 1 0.24 0.55 0.64
105 INT135363 Mecp2 Positive_regulation of Mbd1 1 0.50 0.15 0.64
106 INT302441 Binding of GRIN1 and Grin2b 1 0.10 1.27 0.63
107 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62
108 INT224726 Negative_regulation of Binding of Fgf2 and Cia1 1 0.01 0.92 0.62
109 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
110 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
111 INT224727 Binding of Fgf2 and Cia1 1 0.01 0.91 0.61
112 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
113 INT195666 Binding of PROC and THBD 2 0.40 2.42 0.56
114 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
115 INT251141 Binding of Dlg4 and Grin2b 1 0.14 0.32 0.55
116 INT251143 Binding of Grin2b and Dlg3 1 0.22 0.32 0.55
117 INT164973 Binding of RASA1 and Rgs7 1 0.00 0 0.54
118 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
119 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54
120 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
121 INT164972 Binding of RASA1 and Rgs8 1 0.00 0 0.53
122 INT247265 Mecp2 Regulation of Fos 1 0.25 0.38 0.52
123 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
124 INT208121 Binding of Grin2a and Grin2b 3 0.35 0.06 0.51
125 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
126 INT138353 Foxm1 Positive_regulation of Phosphorylation of Trpv1 1 0.10 0.31 0.51
127 INT138352 Foxm1 Positive_regulation of Trpa1 1 0.05 0.33 0.51
128 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
129 INT135360 Binding of Mecp2 and Aadac 1 0.03 0.19 0.51
130 INT66336 Fgf2 Regulation of Gene_expression of Npy 1 0.12 0.09 0.5
131 INT206010 Foxm1 Positive_regulation of Gene_expression of Il18 1 0.03 0.72 0.5
132 INT330107 Racgap1 Regulation of Positive_regulation of Nox3 1 0.01 0.87 0.49
133 INT86088 Foxm1 Positive_regulation of Binding of Crygs 1 0.04 0 0.49
134 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
135 INT228449 PMAIP1 Negative_regulation of Fgf2 1 0.00 0.07 0.49
136 INT86089 Foxm1 Regulation of Binding of Crygs 1 0.02 0 0.49
137 INT250080 Grin2b Positive_regulation of Ltp 1 0.22 0.19 0.49
138 INT208119 Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.16 0.21 0.49
139 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
140 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
141 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
142 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
143 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
144 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 2 0.00 0.95 0.46
145 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
146 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
147 INT330108 Racgap1 Positive_regulation of Cybb 1 0.03 0.86 0.46
148 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46
149 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
150 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
151 INT72089 TGFB2 Positive_regulation of POMC 1 0.11 0 0.46
152 INT66335 Fgf1 Regulation of Fgf2 1 0.10 0.08 0.45
153 INT191489 Positive_regulation of P2ry2 Negative_regulation of Positive_regulation of Trpv1 1 0.03 0.08 0.44
154 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
155 INT169478 TGFB3 Positive_regulation of Tgfa 1 0.01 0.9 0.44
156 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
157 INT215564 Hmmr Negative_regulation of P2ry2 1 0.00 0 0.44
158 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43
159 INT169465 TGFB3 Positive_regulation of MTG1 1 0.03 0.89 0.43
160 INT292634 IL4 Positive_regulation of Gene_expression of FOXP3 1 0.10 0.42 0.43
161 INT275849 PES1 Positive_regulation of Gene_expression of TNFAIP1 1 0.01 1.28 0.42
162 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
163 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
164 INT13283 Egf Regulation of Fgf2 1 0.49 0.11 0.41
165 INT330110 Racgap1 Regulation of Gene_expression of Ros1 1 0.00 1.12 0.41
166 INT13284 Fgf2 Regulation of Egf 1 0.49 0.11 0.41
167 INT52954 Binding of Pdpn and Flvcr2 1 0.05 0.42 0.41
168 INT105733 Grin2b Negative_regulation of Gene_expression of Grin2a 1 0.22 0.09 0.41
169 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
170 INT296296 Binding of Grin2b and Kcnip3 1 0.24 0 0.4
171 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4
172 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
173 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
174 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
175 INT334533 Binding of Foxq1 and Ngf 1 0.05 0.8 0.38
176 INT249090 FOXL1 Regulation of Regulation of ICAM1 1 0.12 1.03 0.37
177 INT150196 Grm5 Regulation of Grin2b 1 0.45 0 0.36
178 INT97790 Foxm1 Negative_regulation of Gene_expression of Nos2 1 0.03 0.16 0.36
179 INT71925 Binding of Ptprs and Positive_regulation of Racgap1 1 0.10 0 0.35
180 INT249492 Trib3 Regulation of Phosphorylation of Grin2b 1 0.01 0.23 0.35
181 INT280479 Binding of Mecp2 and Sin3a 1 0.00 1.54 0.35
182 INT71924 Ptprs Positive_regulation of Racgap1 1 0.10 0 0.35
183 INT330106 Racgap1 Positive_regulation of Positive_regulation of Mapk8 1 0.01 1.32 0.35
184 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
185 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
186 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
187 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
188 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
189 INT149897 Ihh Positive_regulation of Mmp14 1 0.03 0.93 0.33
190 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
191 INT236006 HTR1A Regulation of Grin2b 1 0.00 0 0.33
192 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
193 INT149895 Ihh Regulation of Localization of Mmp7 1 0.03 0.98 0.33
194 INT295755 Fgf2 Regulation of MMP9 1 0.07 0.99 0.33
195 INT149902 Ihh Positive_regulation of SGCG 1 0.45 0.76 0.32
196 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
197 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
198 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
199 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
200 INT330462 Ngf Positive_regulation of Gene_expression of Adh1 1 0.01 0.57 0.31

Single Events

The table below shows the top 100 pain related interactions that have been reported for embryo development. They are ordered first by their pain relevance and then by number of times they were reported in embryo development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
2 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
3 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
4 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
5 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
6 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
7 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
8 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
9 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
10 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
11 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
12 INT37889 Gene_expression of P2ry2 75 0.65 26.01 23.8
13 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
14 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
15 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
16 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48
17 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29
18 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
19 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
20 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
21 INT1261 Localization of Adh1 63 0.81 19.36 16.09
22 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
23 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32
24 INT61635 Positive_regulation of P2ry2 35 0.56 12.08 14.68
25 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
26 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49
27 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
28 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
29 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
30 INT21632 Positive_regulation of Adh1 32 0.70 15.67 11.65
31 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
32 INT105816 Gene_expression of P2RY2 53 0.78 16.47 9.67
33 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
34 INT29988 Gene_expression of Mecp2 27 0.78 5.45 9.47
35 INT68133 Localization of Fgf2 36 0.81 15.37 9.14
36 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12
37 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
38 INT50767 Positive_regulation of Nanog 14 0.67 3.63 8.56
39 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
40 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
41 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
42 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36
43 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
44 INT112104 Binding of Grin2b 21 0.44 6.78 8.16
45 INT60285 Negative_regulation of Racgap1 27 0.56 21.71 8.14
46 INT92680 Gene_expression of Fgf2 59 0.77 28.11 8.12
47 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
48 INT28358 Gene_expression of Nanog 25 0.70 3.52 7.85
49 INT182750 Gene_expression of Hmgcr 61 0.58 17.23 7.4
50 INT76253 Positive_regulation of P2RY2 29 0.70 13.99 7.33
51 INT4438 Negative_regulation of Localization of Adh1 18 0.59 6.23 6.95
52 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
53 INT95466 Regulation of P2ry2 23 0.56 3.66 6.86
54 INT50337 Negative_regulation of Foxm1 24 0.43 11.12 6.48
55 INT64689 Positive_regulation of Gene_expression of Fgf2 30 0.70 12.05 6.2
56 INT144539 Phosphorylation of Mecp2 3 0.82 6.18 6.2
57 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
58 INT21032 Gene_expression of Adh1 23 0.78 22.1 6.14
59 INT135359 Positive_regulation of Mecp2 4 0.70 4.35 6.05
60 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
61 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
62 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
63 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
64 INT130472 Negative_regulation of Phosphorylation of Grin2b 4 0.40 4.4 5.78
65 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
66 INT55513 Binding of Foxm1 19 0.37 2.37 5.54
67 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
68 INT4598 Negative_regulation of Adh1 15 0.54 4.69 5.33
69 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
70 INT130478 Localization of Grin2b 11 0.75 2.49 5.28
71 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2
72 INT92679 Positive_regulation of Fgf2 13 0.69 11.43 5.18
73 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
74 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
75 INT83735 Gene_expression of Foxm1 41 0.77 22.9 5.07
76 INT116464 Negative_regulation of Birc5 53 0.59 45.4 4.91
77 INT38087 Regulation of Adh1 15 0.61 4.56 4.83
78 INT52952 Binding of Pdpn 8 0.13 3.57 4.79
79 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
80 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
81 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
82 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
83 INT57642 Gene_expression of PCSK1 26 0.76 5.09 4.28
84 INT170348 Regulation of Gene_expression of Grin2b 8 0.60 2.29 4.25
85 INT109219 Negative_regulation of Cdk5r1 5 0.43 1.22 4.25
86 INT112100 Negative_regulation of Gene_expression of Grin2b 6 0.42 3.71 4.24
87 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
88 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
89 INT70801 Gene_expression of Hmgcr 12 0.42 3.08 4.1
90 INT182311 Positive_regulation of Birc5 26 0.67 25.32 4.08
91 INT57157 Gene_expression of TDGF1 5 0.75 3.97 4.02
92 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
93 INT163500 Transcription of Grin2b 3 0.67 3.63 3.8
94 INT139646 Positive_regulation of Positive_regulation of Grin2b 4 0.42 3.89 3.74
95 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
96 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
97 INT318967 Gene_expression of Mecp2 9 0.77 11.52 3.55
98 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
99 INT36142 Negative_regulation of Hmgcr 33 0.46 15.91 3.54
100 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
101 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
102 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
103 INT4261 Positive_regulation of Localization of Adh1 11 0.61 2.04 3.49
104 INT64825 Negative_regulation of Nanog 8 0.57 2.59 3.47
105 INT118270 Regulation of P2RY2 16 0.45 7.02 3.45
106 INT126560 Binding of P2RY2 12 0.44 6.43 3.4
107 INT52839 Regulation of Racgap1 14 0.25 9.46 3.37
108 INT168003 Localization of Fgf2 24 0.80 12.52 3.31
109 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
110 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
111 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
112 INT61547 Regulation of Fgf2 21 0.47 7.23 3.24
113 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
114 INT164087 Gene_expression of TPI1 42 0.78 5.39 3.21
115 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
116 INT148190 Positive_regulation of Transcription of Nanog 1 0.49 0.2 3.17
117 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
118 INT101083 Binding of Fgf2 14 0.42 4.12 3.14
119 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
120 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
121 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
122 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
123 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
124 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96
125 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
126 INT65033 Negative_regulation of Fgf2 21 0.59 12.36 2.94
127 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
128 INT33717 Regulation of Localization of Adh1 15 0.54 3.3 2.91
129 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
130 INT50335 Positive_regulation of Foxm1 20 0.69 5.11 2.81
131 INT122787 Transcription of Nanog 4 0.67 0.78 2.81
132 INT122782 Negative_regulation of Positive_regulation of Nanog 3 0.57 1.15 2.81
133 INT85142 Gene_expression of Gtf2i 5 0.26 2.3 2.76
134 INT201632 Positive_regulation of Cdk5r1 20 0.40 21.6 2.75
135 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74
136 INT91284 Negative_regulation of P2ry2 8 0.25 2.66 2.71
137 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
138 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
139 INT17993 Negative_regulation of RASA1 8 0.41 7.34 2.62
140 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
141 INT27412 Regulation of Nanog 7 0.58 0.81 2.59
142 INT188344 Positive_regulation of Gene_expression of Foxp3 10 0.36 5.97 2.56
143 INT64688 Negative_regulation of Gene_expression of Fgf2 5 0.59 5.07 2.56
144 INT210058 Regulation of ELF3 11 0.29 7.93 2.51
145 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
146 INT80329 Positive_regulation of THBD 12 0.47 20.96 2.45
147 INT163544 Binding of Psen1 40 0.36 15.28 2.42
148 INT70286 Negative_regulation of Positive_regulation of Racgap1 2 0.43 3.78 2.42
149 INT150476 Positive_regulation of ELF3 32 0.56 13.61 2.39
150 INT113203 Regulation of Foxm1 8 0.34 7.5 2.36
151 INT101603 Positive_regulation of Cdk5r1 4 0.56 1.12 2.35
152 INT54515 Positive_regulation of Positive_regulation of Racgap1 6 0.12 2.33 2.34
153 INT70283 Gene_expression of Racgap1 19 0.44 9.64 2.33
154 INT150465 Positive_regulation of Gene_expression of P2ry2 3 0.56 3.48 2.33
155 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32
156 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
157 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
158 INT182318 Regulation of Birc5 25 0.60 23.58 2.29
159 INT65459 Binding of Racgap1 9 0.07 4.57 2.28
160 INT137977 Localization of P2RY2 5 0.80 3.07 2.27
161 INT121543 Positive_regulation of Gene_expression of PCSK1 4 0.29 1.63 2.21
162 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
163 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
164 INT164085 Positive_regulation of Gene_expression of TPI1 4 0.60 0.06 2.09
165 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
166 INT65207 Positive_regulation of Positive_regulation of Fgf2 10 0.70 3.5 2.08
167 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
168 INT43900 Gene_expression of RASA1 13 0.58 12 2.03
169 INT87436 Regulation of Fgf2 6 0.45 3.95 2.03
170 INT60723 Localization of Psen2 5 0.68 2.11 2.02
171 INT68829 Binding of ELF3 14 0.47 7.96 2
172 INT12965 Negative_regulation of RICTOR 3 0.37 0.32 2
173 INT246518 Regulation of Negative_regulation of Grin2b 1 0.38 0.07 1.99
174 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98
175 INT99636 Negative_regulation of Localization of Fgf2 4 0.41 1.32 1.97
176 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
177 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
178 INT151942 Regulation of Negative_regulation of Grin2b 2 0.41 0.41 1.92
179 INT275860 Negative_regulation of Localization of TNFAIP1 1 0.03 4.41 1.91
180 INT144541 Negative_regulation of Gene_expression of Mecp2 3 0.42 1.43 1.9
181 INT64687 Regulation of Gene_expression of Fgf2 7 0.62 2.29 1.89
182 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
183 INT95467 Transcription of P2ry2 7 0.49 1.43 1.87
184 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
185 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
186 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85
187 INT62692 Localization of Nanog 3 0.73 0.82 1.85
188 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
189 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
190 INT158710 Negative_regulation of Binding of Cdk5 1 0.40 0 1.84
191 INT102288 Localization of P2ry2 4 0.55 1.02 1.83
192 INT89618 Positive_regulation of Map1b 1 0.68 2.48 1.81
193 INT74594 Regulation of Transcription of Grin2b 1 0.42 0.17 1.8
194 INT247261 Negative_regulation of Mecp2 1 0.42 1.71 1.78
195 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
196 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
197 INT144538 Regulation of Phosphorylation of Mecp2 2 0.45 1.87 1.77
198 INT230668 Gene_expression of Rasa1 9 0.68 3.25 1.74
199 INT221426 Positive_regulation of Gene_expression of FOXP3 9 0.48 5.98 1.72
200 INT135355 Binding of Mecp2 4 0.37 0.83 1.72
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