GO:0009792

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Name embryo development ending in birth or egg hatching
Categary Process
Go Slim No
Go Link GO:0009792
Unique Molecular Interactions 259
Total Molecular Interactions 323
Total Single Events 2508
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for embryo development ending in birth or egg hatching. They are ordered first by their pain relevance and then by number of times they were reported for embryo development ending in birth or egg hatching. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
3 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
4 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
5 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
6 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
7 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
8 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
9 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
10 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
11 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
12 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
13 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
14 INT147579 Binding of ATF4 and Cyp1a1 1 0.01 0.15 0.54
15 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
16 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
17 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
18 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
19 INT155064 Stat3 Negative_regulation of Tp53bp2 1 0.06 3.69 0.33
20 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
21 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
22 INT104932 AHR Positive_regulation of CYP1A1 1 0.43 0.83 0.31
23 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
24 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
25 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
26 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
27 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
28 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
29 INT335134 PPARA Negative_regulation of Cyp1a1 1 0.47 0 0.28
30 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
31 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
32 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
33 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
34 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
35 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
36 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
37 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
38 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
39 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
40 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
41 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
42 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
43 INT162502 NEUROD1 Regulation of CYP1A1 2 0.07 0.09 0.25
44 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
45 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
46 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
47 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
48 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
49 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
50 INT57171 Binding of RYBP and Cyp1a1 1 0.01 0 0.23
51 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
52 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
53 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
54 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
55 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
56 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
57 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
58 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
59 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
60 INT230455 FOXG1 Negative_regulation of HBS1L 1 0.02 1.73 0.18
61 INT155065 Csf2 Negative_regulation of Tp53bp2 1 0.03 1.88 0.17
62 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
63 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
64 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
65 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
66 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
67 INT65883 Binding of CYP1A1 and PPP4C 1 0.02 0 0.15
68 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
69 INT273561 Binding of CYP1A1 and CYP3A4 1 0.02 0.12 0.15
70 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
71 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
72 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
73 INT57170 Binding of Cyp1a1 and Cyp2b1 1 0.39 0 0.13
74 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
75 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
76 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
77 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
78 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
79 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
80 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
81 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1
82 INT134201 Positive_regulation of Binding of AHR and Cyp1a1 1 0.21 0.07 0.1
83 INT134200 Binding of AHR and Cyp1a1 1 0.16 0.07 0.1
84 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
85 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
86 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1
87 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09
88 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09
89 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
90 INT162506 Gtf3a Regulation of CYP1A1 1 0.00 0.09 0.09
91 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
92 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09
93 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
94 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
95 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08
96 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
97 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
98 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
99 INT22568 Cyp1a1 Positive_regulation of Tcf21 1 0.04 0 0.06
100 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
101 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
102 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
103 INT140291 ROS1 Positive_regulation of TP53 1 0.52 1.27 0.06
104 INT265459 Phosphorylation of TP53 Positive_regulation of Localization of CASP9 1 0.17 1.16 0.05
105 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05
106 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
107 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05
108 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05
109 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
110 INT265454 Phosphorylation of TP53 Positive_regulation of CASP9 1 0.17 1.16 0.05
111 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
112 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05
113 INT193788 ITIH4 Regulation of Phosphorylation of TP53 1 0.07 0.45 0.05
114 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04
115 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04
116 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04
117 INT329230 Negative_regulation of ATIC Positive_regulation of Trp53 1 0.00 0.58 0.04
118 INT329228 ATIC Positive_regulation of Trp53 1 0.01 0.58 0.04
119 INT352619 Bcl2l12 Negative_regulation of Trp53 1 0.27 0.94 0.04
120 INT352613 Binding of Trp53 and Bcl2l12 1 0.23 0.94 0.04
121 INT170457 RASGRP1 Regulation of TP53 1 0.02 0.58 0.04
122 INT201726 Mapk8 Positive_regulation of Positive_regulation of Trp53 1 0.00 0.41 0.04
123 INT260267 Binding of TFAM and TP53 2 0.37 2.1 0.03
124 INT355036 CKAP4 Regulation of Positive_regulation of TP53 1 0.08 0.4 0.03
125 INT266903 Binding of Sod2 and Trp53 1 0.05 0 0.03
126 INT211873 TP53 Positive_regulation of Transcription of CD40 1 0.03 1.44 0.03
127 INT234625 TP53 Positive_regulation of IGFBP3 1 0.29 0.74 0.03
128 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
129 INT265464 CSPG4 Regulation of Gene_expression of TP53 1 0.09 0.23 0.03
130 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
131 INT314686 TP53 Regulation of Gene_expression of MDM2 1 0.21 0.96 0.03
132 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03
133 INT314677 TP53 Regulation of Positive_regulation of CDKN2A 1 0.27 0.97 0.03
134 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03
135 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03
136 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03
137 INT314690 TP53 Regulation of Gene_expression of ZBTB7A 1 0.33 0.97 0.03
138 INT211872 TP53 Positive_regulation of CD40 1 0.03 1.44 0.03
139 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0
140 INT352615 Binding of Mdm4 and Trp53 1 0.30 1.36 0
141 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0
142 INT315395 Regulation of Binding of IFNA1 and Tp53 1 0.00 0.46 0
143 INT304020 AR Regulation of TP53 1 0.24 1.11 0
144 INT315221 Tpt1 Regulation of Positive_regulation of Trp53 1 0.33 1.04 0
145 INT203901 HIVEP1 Positive_regulation of Gene_expression of TP53 1 0.04 0.86 0
146 INT104540 FOXG1 Regulation of Lipc 1 0.02 0 0
147 INT232006 Binding of Trp53 and Tsp1 1 0.06 0.75 0
148 INT333685 Binding of Trp53 and Hdac1 1 0.26 0.55 0
149 INT333688 Trp53 Positive_regulation of Bcl2 1 0.45 2.51 0
150 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0
151 INT333690 Hr Negative_regulation of Transcription of Trp53 1 0.23 0.51 0
152 INT217776 TP53 Regulation of MITF 1 0.00 1.28 0
153 INT334322 Binding of RB1 and TP53 1 0.34 2 0
154 INT342007 Mta1 Regulation of Trp53 1 0.15 0.15 0
155 INT179095 Myc Positive_regulation of Gene_expression of Trp53 1 0.43 0.83 0
156 INT315397 Binding of IFNA1 and Tp53 1 0.00 0.43 0
157 INT333689 Hr Positive_regulation of Protein_catabolism of Trp53 1 0.25 1.71 0
158 INT345489 TP53 Positive_regulation of PMAIP1 1 0.05 0.6 0
159 INT286044 Wwox Positive_regulation of Tp53 1 0.05 0.63 0
160 INT347162 MDM2 Negative_regulation of TP53 1 0.02 1.09 0
161 INT235645 TP53 Regulation of EPHA2 1 0.10 0.97 0
162 INT241256 TP53 Regulation of OPCML 1 0.12 1.31 0
163 INT305542 Binding of Rb1 and Trp53 1 0.00 0.9 0
164 INT352625 Trp53 Regulation of CEL 1 0.00 0.71 0
165 INT320714 Gene_expression of MDM2 Negative_regulation of TP53 1 0.16 0.88 0
166 INT333455 ATM Positive_regulation of TP53 1 0.18 0 0
167 INT204234 Binding of CDKN2A and TP53 1 0.43 1.27 0
168 INT177793 EGR1 Positive_regulation of Negative_regulation of TP53 1 0.18 0.44 0
169 INT284232 Binding of TP53 and HNRNPUL1 1 0.26 0.88 0
170 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0
171 INT306256 MDM2 Negative_regulation of Positive_regulation of TP53 1 0.23 0.44 0
172 INT278186 Binding of TP53 and GOPC 1 0.02 0.85 0
173 INT337708 Naf1 Regulation of Gene_expression of Tp53 1 0.09 0.22 0
174 INT345337 Binding of TP53 and BCC1 1 0.11 1.05 0
175 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0
176 INT353437 Negative_regulation of Trp53 Positive_regulation of Gene_expression of Cdkn2a 1 0.24 0.59 0
177 INT268513 MIR34A Regulation of Gene_expression of TP53 1 0.00 0.9 0
178 INT172604 Binding of EP300 and TP53 1 0.00 0 0
179 INT193118 Trp53 Regulation of Gene_expression of Birc5 1 0.19 0.86 0
180 INT225564 Ncoa6 Regulation of Trp53 1 0.04 0.93 0
181 INT304025 Binding of PIK3CA and TP53 1 0.30 0.67 0
182 INT352617 Mdm2 Positive_regulation of Positive_regulation of Trp53 1 0.20 2.56 0
183 INT337639 TP53 Regulation of Gene_expression of MIR34A 1 0.08 1.19 0
184 INT350983 TP53 Regulation of VEGFA 1 0.03 0.61 0
185 INT276380 Binding of PIM1 and Trp53 1 0.01 0.66 0
186 INT337680 Binding of TP53 and Scrib 1 0.03 1.6 0
187 INT325375 Binding of Tp53 and Positive_regulation of Positive_regulation of PARP1 1 0.05 0.59 0
188 INT187575 TP53 Regulation of Gene_expression of Birc5 1 0.05 1.1 0
189 INT217781 Binding of MITF and TP53 1 0.00 1.2 0
190 INT267258 Binding of TP53 and BCL11B 1 0.09 0.42 0
191 INT305540 Binding of Trp53 and Tpt1 1 0.07 0.9 0
192 INT333697 Binding of Hr and Trp53 1 0.19 0.56 0
193 INT113343 Phosphorylation of TP53 Positive_regulation of Gene_expression of BAX 1 0.11 0.14 0
194 INT179090 Positive_regulation of Myc Regulation of Gene_expression of Trp53 1 0.23 0.69 0
195 INT301466 Smyd2 Negative_regulation of Binding of Trp53 1 0.20 0.3 0
196 INT338969 Binding of ING1 and TP53 1 0.13 0.98 0
197 INT235650 TP53 Regulation of EFNA1 1 0.06 0.97 0
198 INT301468 Smyd2 Negative_regulation of Trp53 1 0.20 0.31 0
199 INT197295 Positive_regulation of Binding of Ahr and Cyp1a1 1 0.20 0 0
200 INT337637 SIRT1 Negative_regulation of TP53 1 0.23 1.49 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for embryo development ending in birth or egg hatching. They are ordered first by their pain relevance and then by number of times they were reported in embryo development ending in birth or egg hatching. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
2 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
3 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
4 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
5 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
6 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
7 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
8 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
9 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
10 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
11 INT185 Regulation of Cyp1a1 18 0.54 2.71 5.56
12 INT60585 Regulation of TP53 59 0.59 54.55 5.21
13 INT2435 Negative_regulation of Cyp1a1 15 0.58 3.32 5.16
14 INT186 Positive_regulation of Cyp1a1 30 0.70 5 5.02
15 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
16 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
17 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
18 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
19 INT23220 Positive_regulation of FOXG1 10 0.43 2.86 3.49
20 INT8103 Binding of TP53 46 0.44 40.2 2.96
21 INT9242 Negative_regulation of FOXG1 13 0.40 1.43 2.86
22 INT22212 Gene_expression of CYP1A1 34 0.76 10.11 2.77
23 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
24 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
25 INT55952 Transcription of TP53 16 0.61 12.14 2.36
26 INT23219 Regulation of FOXG1 8 0.22 1.32 2.34
27 INT36267 Positive_regulation of CYP1A1 29 0.69 11.09 2.01
28 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
29 INT19409 Binding of Cyp1a1 12 0.48 2.58 1.97
30 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
31 INT65855 Localization of TP53 18 0.76 17.08 1.89
32 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
33 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
34 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
35 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
36 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
37 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
38 INT172953 Binding of Trp53 33 0.37 20.76 1.41
39 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
40 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
41 INT145221 Binding of Tp53 10 0.37 8.59 1.37
42 INT17862 Localization of Cyp1a1 5 0.74 0.34 1.34
43 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
44 INT13674 Gene_expression of Cyp1a1 13 0.65 2.22 1.25
45 INT174156 Localization of Trp53 16 0.72 13.52 1.18
46 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
47 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
48 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
49 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
50 INT9243 Gene_expression of FOXG1 14 0.53 7.52 1.02
51 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
52 INT68220 Binding of CYP1A1 8 0.48 0.8 0.99
53 INT17330 Binding of FOXG1 3 0.33 0.23 0.83
54 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
55 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
56 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
57 INT199649 Gene_expression of Fxn 12 0.72 20.9 0.74
58 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
59 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
60 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
61 INT115826 Transcription of Cyp1a1 4 0.52 1.15 0.53
62 INT2438 Regulation of Regulation of Cyp1a1 1 0.27 0 0.52
63 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
64 INT250845 Protein_catabolism of Fgf8 1 0.98 1.64 0.48
65 INT268007 Gene_expression of Fgf8 8 0.72 1.38 0.47
66 INT277465 Regulation of Gene_expression of Fgf8 2 0.25 0.43 0.43
67 INT27414 Positive_regulation of Negative_regulation of Cyp1a1 1 0.49 0.44 0.41
68 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
69 INT115835 Negative_regulation of Positive_regulation of Cyp1a1 2 0.32 1.35 0.36
70 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
71 INT250826 Transcription of Fgf8 1 0.71 0.71 0.34
72 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
73 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
74 INT13676 Negative_regulation of Gene_expression of Cyp1a1 1 0.33 0.1 0.29
75 INT96886 Positive_regulation of Gene_expression of CYP1A1 8 0.64 3.15 0.27
76 INT99628 Positive_regulation of Gene_expression of Cyp1a1 4 0.25 1.3 0.27
77 INT115926 Negative_regulation of Positive_regulation of CYP1A1 1 0.30 0.16 0.27
78 INT166960 Positive_regulation of Negative_regulation of TP53 2 0.25 1.65 0.26
79 INT52176 Positive_regulation of Binding of Cyp1a1 1 0.44 0 0.26
80 INT314729 Regulation of Localization of TP53 1 0.30 2.5 0.25
81 INT250836 Binding of Fgf8 3 0.35 0.66 0.24
82 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
83 INT115834 Positive_regulation of Transcription of Cyp1a1 2 0.38 0.64 0.23
84 INT156886 Positive_regulation of Localization of TP53 1 0.48 0.87 0.23
85 INT250833 Localization of Fgf8 1 0.74 0.46 0.21
86 INT250842 Negative_regulation of Binding of Fgf8 1 0.43 0.33 0.21
87 INT65885 Negative_regulation of CYP1A1 2 0.18 0.64 0.2
88 INT96884 Regulation of Gene_expression of CYP1A1 2 0.60 0.54 0.2
89 INT96889 Negative_regulation of Gene_expression of CYP1A1 2 0.42 0.9 0.2
90 INT104539 Regulation of Positive_regulation of FOXG1 1 0.38 0.2 0.19
91 INT161283 Positive_regulation of Positive_regulation of FOXG1 1 0.02 0 0.17
92 INT155056 Gene_expression of Tp53bp2 1 0.12 1.89 0.17
93 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
94 INT337078 Negative_regulation of Localization of Trp53 1 0.20 1.3 0.17
95 INT155055 Negative_regulation of Tp53bp2 1 0.08 1.81 0.16
96 INT134195 Regulation of Transcription of Cyp1a1 1 0.13 0.14 0.16
97 INT179086 Positive_regulation of Negative_regulation of Trp53 5 0.50 4.78 0.15
98 INT125081 Positive_regulation of Binding of TP53 2 0.46 1.2 0.15
99 INT207805 Negative_regulation of Phosphorylation of Trp53 2 0.18 0.98 0.15
100 INT286749 Regulation of Localization of Trp53 1 0.06 1.39 0.15
101 INT199642 Positive_regulation of Fxn 3 0.41 3.6 0.14
102 INT199640 Positive_regulation of Positive_regulation of Fxn 2 0.41 2.97 0.14
103 INT250835 Positive_regulation of Fgf8 1 0.50 0.42 0.14
104 INT168244 Regulation of Transcription of Tp53 1 0.33 0.57 0.13
105 INT17866 Positive_regulation of Localization of Cyp1a1 1 0.49 0 0.12
106 INT349935 Transcription of CYP1A1 1 0.47 1.22 0.12
107 INT199652 Negative_regulation of Fxn 3 0.54 12.37 0.11
108 INT68218 Regulation of Positive_regulation of CYP1A1 3 0.45 2.35 0.1
109 INT297456 Protein_catabolism of Tp53 1 0.11 0.72 0.1
110 INT111139 Localization of Tp53 4 0.45 2.4 0.09
111 INT41890 Positive_regulation of Gene_expression of FOXG1 2 0.32 1.04 0.09
112 INT17863 Regulation of Positive_regulation of Cyp1a1 1 0.27 0 0.09
113 INT199646 Transcription of Fxn 2 0.67 4.78 0.08
114 INT199643 Phosphorylation of Fxn 1 0.40 1.04 0.08
115 INT199655 Negative_regulation of Gene_expression of Fxn 2 0.47 3.34 0.07
116 INT352605 Regulation of Negative_regulation of Trp53 1 0.45 0.72 0.07
117 INT274054 Localization of CYP1A1 1 0.12 0 0.07
118 INT101430 Positive_regulation of Negative_regulation of FOXG1 1 0.37 0 0.07
119 INT315598 Localization of FXN 1 0.43 1.04 0.07
120 INT274056 Protein_catabolism of CYP1A1 1 0.15 0 0.06
121 INT315630 Gene_expression of FXN 8 0.64 20.05 0.05
122 INT199654 Positive_regulation of Gene_expression of Fxn 3 0.64 2.95 0.05
123 INT171421 Regulation of Positive_regulation of TP53 1 0.48 0.45 0.05
124 INT68219 Positive_regulation of Binding of CYP1A1 1 0.50 0 0.05
125 INT315213 Negative_regulation of Binding of Trp53 1 0.32 0.11 0.05
126 INT311668 Regulation of Regulation of TP53 2 0.36 3.58 0.04
127 INT305536 Positive_regulation of Binding of Trp53 1 0.35 0.32 0.04
128 INT199641 Regulation of Transcription of Fxn 1 0.29 1.89 0.04
129 INT199648 Regulation of Fxn 1 0.29 2.14 0.04
130 INT199651 Binding of Fxn 3 0.30 1.45 0.03
131 INT217802 Regulation of Transcription of TP53 2 0.37 0.81 0.03
132 INT259061 Negative_regulation of Regulation of TP53 2 0.10 2.23 0.03
133 INT291518 Positive_regulation of Negative_regulation of Fxn 1 0.47 1.1 0.03
134 INT178927 Regulation of Gene_expression of Tp53 6 0.26 2.23 0
135 INT315563 Positive_regulation of Gene_expression of FXN 4 0.41 5.05 0
136 INT333669 Positive_regulation of Transcription of Trp53 3 0.45 2.33 0
137 INT167112 Regulation of CYP1A1 3 0.26 0.37 0
138 INT250698 Positive_regulation of Transcription of TP53 3 0.18 3.68 0
139 INT315635 Positive_regulation of FXN 2 0.41 5.76 0
140 INT113348 Negative_regulation of Binding of TP53 2 0.28 1.49 0
141 INT315628 Negative_regulation of Gene_expression of FXN 2 0.36 2.37 0
142 INT214913 Positive_regulation of Positive_regulation of Tp53 2 0.08 2.47 0
143 INT217820 Regulation of Negative_regulation of TP53 2 0.37 1.92 0
144 INT204059 Positive_regulation of Phosphorylation of Tp53 1 0.07 0.76 0
145 INT291511 Positive_regulation of Transcription of Fxn 1 0.47 0.09 0
146 INT333668 Regulation of Protein_catabolism of Trp53 1 0.24 1.58 0
147 INT315614 Negative_regulation of Transcription of FXN 1 0.25 0.82 0
148 INT294588 Positive_regulation of Positive_regulation of CYP1A1 1 0.07 0.25 0
149 INT331131 Regulation of Gene_expression of FXN 1 0.37 1.49 0
150 INT291516 Negative_regulation of Transcription of Fxn 1 0.54 0.77 0
151 INT315637 Transcription of FXN 1 0.40 1.44 0
152 INT315555 Binding of FXN 1 0.28 1.29 0
153 INT333671 Regulation of Transcription of Trp53 1 0.24 0.83 0
154 INT179076 Negative_regulation of Protein_catabolism of Trp53 1 0.32 0.43 0
155 INT85223 Regulation of Localization of Cyp1a1 1 0.03 0.1 0
156 INT167111 Regulation of Binding of CYP1A1 1 0.43 0 0
157 INT179957 Positive_regulation of Binding of Tp53 1 0.08 0.48 0
158 INT250830 Regulation of Protein_catabolism of Fgf8 1 0.45 0.08 0
159 INT311651 Positive_regulation of Fgf8 1 0.46 0.26 0
160 INT291507 Regulation of Negative_regulation of Fxn 1 0.37 0.87 0
161 INT333663 Positive_regulation of Protein_catabolism of Trp53 1 0.45 0.84 0
162 INT333662 Negative_regulation of Transcription of Trp53 1 0.53 1.15 0
163 INT250846 Positive_regulation of Protein_catabolism of Fgf8 1 0.50 0.07 0
164 INT291512 Regulation of Gene_expression of Fxn 1 0.37 0.06 0
165 INT223765 Negative_regulation of Positive_regulation of Tp53 1 0.07 1.69 0
166 INT305295 Regulation of Binding of TP53 1 0.39 1.09 0
167 INT197269 Regulation of Gene_expression of Cyp1a1 1 0.16 0 0
168 INT331130 Negative_regulation of FXN 1 0.48 4.93 0
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