GO:0009812

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Name flavonoid metabolic process
Categary Process
Go Slim No
Go Link GO:0009812
Unique Molecular Interactions 69
Total Molecular Interactions 97
Total Single Events 1199
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for flavonoid metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for flavonoid metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
2 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
3 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
4 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
5 INT168459 Sult1a1 Negative_regulation of Gene_expression of Arr3 1 0.05 2.98 1.23
6 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
7 INT349576 Binding of Ugt2b and Sult1a1 1 0.00 0.45 1.03
8 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87
9 INT168455 Sult1a1 Negative_regulation of Nos2 1 0.08 1.99 0.79
10 INT168457 Sult1a1 Positive_regulation of Cat 1 0.15 1.56 0.78
11 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75
12 INT155457 Tnfrsf1a Positive_regulation of Mapk14 1 0.20 1.17 0.67
13 INT155458 Tnfrsf1a Regulation of Gene_expression of Il6 1 0.22 1.11 0.63
14 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
15 INT147579 Binding of ATF4 and Cyp1a1 1 0.01 0.15 0.54
16 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
17 INT252634 Binding of TNF and Tnfrsf1a 4 0.02 2.4 0.46
18 INT327995 Positive_regulation of TRPV1 Positive_regulation of Tnfrsf1a 1 0.16 0.63 0.46
19 INT80679 Abat Regulation of Localization of Sult1b1 1 0.01 0 0.44
20 INT168460 Sult1a1 Negative_regulation of Gene_expression of Ifih1 1 0.02 0.96 0.41
21 INT168463 Sult1a1 Negative_regulation of TNF 1 0.01 1 0.4
22 INT168458 Sult1a1 Negative_regulation of Tnf 1 0.09 1 0.4
23 INT168461 Sult1a1 Positive_regulation of Gpx1 1 0.12 0.83 0.39
24 INT168454 Sult1a1 Negative_regulation of Ifih1 1 0.02 0.89 0.39
25 INT33862 Ca2 Positive_regulation of Positive_regulation of Sult1b1 1 0.07 0.07 0.37
26 INT227904 TNFRSF1A Regulation of TNF 1 0.01 0.41 0.36
27 INT77791 fut10 Regulation of Regulation of Tnfrsf1a 1 0.02 0.85 0.36
28 INT77792 fut10 Negative_regulation of Positive_regulation of Tnfrsf1a 1 0.04 0.82 0.32
29 INT104932 AHR Positive_regulation of CYP1A1 1 0.43 0.83 0.31
30 INT335134 PPARA Negative_regulation of Cyp1a1 1 0.47 0 0.28
31 INT5935 Por Regulation of Oprm1 1 0.19 0.51 0.28
32 INT162502 NEUROD1 Regulation of CYP1A1 2 0.07 0.09 0.25
33 INT57171 Binding of RYBP and Cyp1a1 1 0.01 0 0.23
34 INT248171 Epo Regulation of Sult1a1 1 0.08 0.11 0.21
35 INT60523 Binding of IL1B and TNFRSF1A 1 0.25 1.73 0.21
36 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
37 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
38 INT65883 Binding of CYP1A1 and PPP4C 1 0.02 0 0.15
39 INT273561 Binding of CYP1A1 and CYP3A4 1 0.02 0.12 0.15
40 INT139336 Il1b Regulation of Tnfrsf1a 1 0.27 1.3 0.14
41 INT139338 Cts8 Regulation of Tnfrsf1a 1 0.05 1.3 0.14
42 INT139346 Cts8 Regulation of Gene_expression of Tnfrsf1a 1 0.05 1.3 0.14
43 INT139347 Il1b Regulation of Gene_expression of Tnfrsf1a 1 0.27 1.3 0.14
44 INT57170 Binding of Cyp1a1 and Cyp2b1 1 0.39 0 0.13
45 INT252631 Binding of Casp3 and Tnfrsf1a 1 0.10 0.69 0.13
46 INT141881 Binding of MECOM and Tnfrsf1a 1 0.00 1.17 0.13
47 INT235775 Binding of Tnfrsf1a and Tradd 3 0.31 3 0.12
48 INT352488 Binding of EPO and TNFRSF1A 1 0.14 0.18 0.12
49 INT134201 Positive_regulation of Binding of AHR and Cyp1a1 1 0.21 0.07 0.1
50 INT134200 Binding of AHR and Cyp1a1 1 0.16 0.07 0.1
51 INT162506 Gtf3a Regulation of CYP1A1 1 0.00 0.09 0.09
52 INT238472 Binding of AVP and POR 1 0.02 0.85 0.09
53 INT342232 Binding of POR and SEPP1 1 0.02 0.75 0.08
54 INT22568 Cyp1a1 Positive_regulation of Tcf21 1 0.04 0 0.06
55 INT285383 Cars Regulation of Regulation of Sult1a1 1 0.01 0 0.06
56 INT206429 Binding of PRCP and SULT1B1 1 0.16 0.14 0.03
57 INT206428 Binding of SULT1B1 and ASAP1 1 0.28 0.13 0.03
58 INT264979 Binding of POR and BAG3 1 0.15 0.38 0
59 INT292560 Binding of TNFRSF1A and TRAF2 1 0.08 0.09 0
60 INT122293 Binding of SULT1A1 and SULT1A3 1 0.37 0 0
61 INT347413 Tlr4 Regulation of Gene_expression of Tnfrsf1a 1 0.01 0.12 0
62 INT197295 Positive_regulation of Binding of Ahr and Cyp1a1 1 0.20 0 0
63 INT292566 Binding of TNFRSF1A and MADD 1 0.05 0.09 0
64 INT292562 Binding of TNFRSF1A and TRADD 1 0.11 0.09 0
65 INT292559 Binding of TNFRSF1A and FADD 1 0.05 0.09 0
66 INT122295 Binding of SULT1E1 and SULT1A1 1 0.36 0 0
67 INT292564 Binding of TNFRSF1A and RIPK1 1 0.06 0.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for flavonoid metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in flavonoid metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2499 Positive_regulation of Sult1b1 51 0.43 2.83 32.38
2 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03
3 INT12114 Positive_regulation of Tnfrsf1a 46 0.69 36.26 22.54
4 INT7258 Localization of Sult1b1 42 0.68 0.17 17.85
5 INT2496 Gene_expression of Sult1b1 32 0.66 3 10.97
6 INT2500 Negative_regulation of Positive_regulation of Sult1b1 13 0.18 0.6 8.6
7 INT77790 Positive_regulation of Gene_expression of Tnfrsf1a 16 0.67 15.88 8.5
8 INT2501 Positive_regulation of Positive_regulation of Sult1b1 19 0.19 2.38 7.16
9 INT6229 Positive_regulation of Gene_expression of Sult1b1 18 0.22 2.21 6.04
10 INT15132 Gene_expression of TNFRSF1A 33 0.75 20.09 5.93
11 INT185 Regulation of Cyp1a1 18 0.54 2.71 5.56
12 INT2435 Negative_regulation of Cyp1a1 15 0.58 3.32 5.16
13 INT2497 Regulation of Positive_regulation of Sult1b1 7 0.23 0.49 5.11
14 INT186 Positive_regulation of Cyp1a1 30 0.70 5 5.02
15 INT118230 Binding of Tnfrsf1a 15 0.42 7.63 4.39
16 INT23440 Negative_regulation of Sult1b1 12 0.45 1.77 4.33
17 INT7257 Positive_regulation of Localization of Sult1b1 8 0.59 0 3.91
18 INT77786 Negative_regulation of Tnfrsf1a 5 0.56 5.03 3.58
19 INT77788 Regulation of Tnfrsf1a 14 0.57 11.24 3.53
20 INT96700 Positive_regulation of Positive_regulation of Tnfrsf1a 6 0.69 3.93 3.42
21 INT52899 Positive_regulation of TNFRSF1A 16 0.46 19.04 3.34
22 INT7256 Negative_regulation of Localization of Sult1b1 5 0.37 0 2.81
23 INT2502 Regulation of Gene_expression of Sult1b1 5 0.11 0.92 2.8
24 INT22212 Gene_expression of CYP1A1 34 0.76 10.11 2.77
25 INT61231 Gene_expression of SULT1A1 14 0.75 3.01 2.76
26 INT38384 Regulation of Por 5 0.47 0.58 2.4
27 INT54969 Binding of Sult1a1 4 0.35 1.4 2.18
28 INT12131 Gene_expression of POR 17 0.77 9.42 2.17
29 INT36267 Positive_regulation of CYP1A1 29 0.69 11.09 2.01
30 INT19409 Binding of Cyp1a1 12 0.48 2.58 1.97
31 INT59302 Positive_regulation of POR 19 0.49 15.18 1.95
32 INT148705 Binding of TNFRSF1A 8 0.38 5.19 1.81
33 INT21822 Regulation of SULT1A1 3 0.62 0 1.75
34 INT60528 Negative_regulation of TNFRSF1A 6 0.42 4.86 1.45
35 INT107924 Localization of Tnfrsf1a 5 0.70 3.86 1.37
36 INT77785 Negative_regulation of Gene_expression of Tnfrsf1a 4 0.56 3.1 1.35
37 INT17862 Localization of Cyp1a1 5 0.74 0.34 1.34
38 INT151 Positive_regulation of Por 5 0.62 0.42 1.31
39 INT13674 Gene_expression of Cyp1a1 13 0.65 2.22 1.25
40 INT49013 Gene_expression of Por 6 0.75 2.19 1.22
41 INT37171 Negative_regulation of SULT1A1 6 0.55 0.18 1.2
42 INT77782 Negative_regulation of Positive_regulation of Tnfrsf1a 3 0.41 1.21 1.16
43 INT265004 Positive_regulation of Binding of Tnfrsf1a 1 0.36 1.23 1.1
44 INT295326 Gene_expression of Sult1a1 2 0.65 1.29 1.06
45 INT122647 Transcription of Tnfrsf1a 5 0.60 2.63 1.02
46 INT115821 Transcription of Por 1 0.33 0.51 1.02
47 INT49012 Regulation of Gene_expression of Por 1 0.44 0 1.02
48 INT68220 Binding of CYP1A1 8 0.48 0.8 0.99
49 INT139333 Regulation of Gene_expression of Tnfrsf1a 3 0.40 5.41 0.98
50 INT23441 Negative_regulation of Gene_expression of Sult1b1 4 0.14 0.3 0.89
51 INT98131 Regulation of TNFRSF1A 5 0.31 5.28 0.76
52 INT37113 Positive_regulation of Sult1a1 3 0.44 0.81 0.75
53 INT83743 Gene_expression of SULT1B1 7 0.76 0.93 0.71
54 INT58960 Regulation of POR 5 0.25 1.04 0.68
55 INT62302 Regulation of Localization of Sult1b1 2 0.03 0 0.65
56 INT257406 Localization of TNFRSF1A 3 0.46 2.6 0.55
57 INT51532 Negative_regulation of Sult1a1 2 0.50 1.72 0.55
58 INT115826 Transcription of Cyp1a1 4 0.52 1.15 0.53
59 INT2438 Regulation of Regulation of Cyp1a1 1 0.27 0 0.52
60 INT40164 Binding of Por 2 0.37 0.5 0.51
61 INT37013 Negative_regulation of Sult1a1 3 0.57 0.35 0.48
62 INT80677 Regulation of Sult1b1 1 0.02 0 0.44
63 INT45729 Positive_regulation of Negative_regulation of Sult1b1 1 0.39 0 0.43
64 INT265 Negative_regulation of Por 4 0.59 0.34 0.41
65 INT27414 Positive_regulation of Negative_regulation of Cyp1a1 1 0.49 0.44 0.41
66 INT253242 Positive_regulation of Transcription of Tnfrsf1a 2 0.44 0.77 0.38
67 INT115835 Negative_regulation of Positive_regulation of Cyp1a1 2 0.32 1.35 0.36
68 INT77783 Regulation of Positive_regulation of Tnfrsf1a 1 0.44 0.85 0.36
69 INT12249 Binding of POR 5 0.35 2.76 0.35
70 INT202106 Positive_regulation of Gene_expression of TNFRSF1A 3 0.22 1.17 0.31
71 INT56192 Regulation of Sult1a1 3 0.44 0.85 0.31
72 INT13676 Negative_regulation of Gene_expression of Cyp1a1 1 0.33 0.1 0.29
73 INT96886 Positive_regulation of Gene_expression of CYP1A1 8 0.64 3.15 0.27
74 INT12132 Positive_regulation of Gene_expression of POR 5 0.31 1.96 0.27
75 INT99628 Positive_regulation of Gene_expression of Cyp1a1 4 0.25 1.3 0.27
76 INT301726 Negative_regulation of Positive_regulation of Sult1a1 1 0.04 0.35 0.27
77 INT295323 Positive_regulation of Localization of Sult1a1 1 0.49 1.3 0.27
78 INT115926 Negative_regulation of Positive_regulation of CYP1A1 1 0.30 0.16 0.27
79 INT295325 Localization of Sult1a1 1 0.73 1.29 0.27
80 INT52176 Positive_regulation of Binding of Cyp1a1 1 0.44 0 0.26
81 INT115834 Positive_regulation of Transcription of Cyp1a1 2 0.38 0.64 0.23
82 INT206445 Binding of SULT1A1 2 0.30 0.24 0.23
83 INT114896 Negative_regulation of Positive_regulation of TNFRSF1A 1 0.17 0.83 0.23
84 INT65885 Negative_regulation of CYP1A1 2 0.18 0.64 0.2
85 INT96884 Regulation of Gene_expression of CYP1A1 2 0.60 0.54 0.2
86 INT96889 Negative_regulation of Gene_expression of CYP1A1 2 0.42 0.9 0.2
87 INT206433 Negative_regulation of SULT1B1 3 0.48 1.25 0.18
88 INT64189 Protein_catabolism of POR 1 0.37 0.16 0.18
89 INT21821 Localization of SULT1A1 1 0.73 0 0.18
90 INT269999 Regulation of Gene_expression of TNFRSF1A 2 0.44 0.53 0.17
91 INT134195 Regulation of Transcription of Cyp1a1 1 0.13 0.14 0.16
92 INT340783 Transcription of TNFRSF1A 1 0.17 0.37 0.13
93 INT37114 Localization of Sult1a1 1 0.55 0 0.13
94 INT340784 Positive_regulation of Transcription of TNFRSF1A 1 0.17 0.37 0.13
95 INT115825 Positive_regulation of Gene_expression of Por 2 0.22 0.47 0.12
96 INT17866 Positive_regulation of Localization of Cyp1a1 1 0.49 0 0.12
97 INT349935 Transcription of CYP1A1 1 0.47 1.22 0.12
98 INT167018 Negative_regulation of POR 3 0.37 1.9 0.11
99 INT326802 Protein_catabolism of SULT1A1 1 0.08 0.38 0.11
100 INT68218 Regulation of Positive_regulation of CYP1A1 3 0.45 2.35 0.1
101 INT115833 Negative_regulation of Transcription of Por 1 0.20 0.52 0.09
102 INT17863 Regulation of Positive_regulation of Cyp1a1 1 0.27 0 0.09
103 INT115828 Negative_regulation of Gene_expression of Por 1 0.20 0.52 0.09
104 INT206462 Positive_regulation of SULT1B1 1 0.39 0 0.08
105 INT98128 Positive_regulation of Regulation of TNFRSF1A 2 0.30 1.95 0.07
106 INT274054 Localization of CYP1A1 1 0.12 0 0.07
107 INT67606 Localization of POR 3 0.68 1.22 0.06
108 INT326140 Transcription of SULT1B1 1 0.17 0.87 0.06
109 INT274056 Protein_catabolism of CYP1A1 1 0.15 0 0.06
110 INT285350 Regulation of Sult1a1 1 0.01 0 0.06
111 INT104466 Binding of Sult1a1 1 0.17 0.48 0.05
112 INT68219 Positive_regulation of Binding of CYP1A1 1 0.50 0 0.05
113 INT326141 Localization of SULT1B1 1 0.24 0.63 0.04
114 INT292575 Phosphorylation of TNFRSF1A 1 0.39 0.2 0.04
115 INT206453 Binding of SULT1B1 1 0.31 0.13 0.03
116 INT167112 Regulation of CYP1A1 3 0.26 0.37 0
117 INT292583 Negative_regulation of Binding of TNFRSF1A 1 0.21 0.15 0
118 INT323616 Phosphorylation of POR 1 0.05 0.7 0
119 INT323617 Positive_regulation of Phosphorylation of POR 1 0.03 0.7 0
120 INT294588 Positive_regulation of Positive_regulation of CYP1A1 1 0.07 0.25 0
121 INT264980 Transcription of POR 1 0.38 0.73 0
122 INT292594 Negative_regulation of Gene_expression of TNFRSF1A 1 0.20 0.06 0
123 INT326807 Positive_regulation of SULT1A1 1 0.06 0.1 0
124 INT85223 Regulation of Localization of Cyp1a1 1 0.03 0.1 0
125 INT167111 Regulation of Binding of CYP1A1 1 0.43 0 0
126 INT326801 Regulation of Gene_expression of SULT1A1 1 0.03 0.06 0
127 INT191529 Negative_regulation of Positive_regulation of POR 1 0.02 1.5 0
128 INT197269 Regulation of Gene_expression of Cyp1a1 1 0.16 0 0
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