GO:0009950

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Name dorsal/ventral axis specification
Categary Process
Go Slim No
Go Link GO:0009950
Unique Molecular Interactions 50
Total Molecular Interactions 80
Total Single Events 376
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for dorsal/ventral axis specification. They are ordered first by their pain relevance and then by number of times they were reported for dorsal/ventral axis specification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
2 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
3 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31
4 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
5 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17
6 INT223535 Binding of HAND1 and Pax6 1 0.33 0.92 0.13
7 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
8 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
9 INT223526 Binding of Pax6 and Tcf3 1 0.33 0.92 0.13
10 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
11 INT233510 Wnt5a Positive_regulation of Gene_expression of Il12a 1 0.03 0.33 0.1
12 INT211960 Wnt5a Positive_regulation of Car2 1 0.13 0.38 0.08
13 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08
14 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
15 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
16 INT293982 MYC Negative_regulation of SFRP1 1 0.21 0.62 0
17 INT302321 Negative_regulation of Binding of Lrp6 and SOST 1 0.16 0.26 0
18 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0
19 INT335884 Akt1 Regulation of Positive_regulation of Wnt5a 1 0.03 0.15 0
20 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
21 INT251072 Wnt3a Positive_regulation of Axin2 1 0.23 0.29 0
22 INT136693 Gtf3a Positive_regulation of Ctnnb1 1 0.05 0 0
23 INT287885 Binding of DVL1 and AXIN1 1 0.02 0 0
24 INT302320 Binding of Lrp6 and SOST 1 0.18 0.26 0
25 INT236724 Binding of AXIN1 and Ctnnd2 1 0.39 1.03 0
26 INT185271 Pax6 Regulation of Psmd1 1 0.02 0 0
27 INT283361 AXIN2 Negative_regulation of GSK 1 0.09 1.67 0
28 INT335887 Akt1 Regulation of Lrp6 1 0.06 0.15 0
29 INT220821 Binding of MAX and Ctnnb1 1 0.09 0.13 0
30 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0
31 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0
32 INT347123 Binding of Axin2 and Lrp1 1 0.08 0.2 0
33 INT315194 Binding of SFRP1 and Slc10a1 1 0.02 8.85 0
34 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0
35 INT283362 AXIN2 Negative_regulation of APC 1 0.10 1.67 0
36 INT352689 VAX2 Positive_regulation of HIST1H1B 1 0.01 0.59 0
37 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0
38 INT315187 Binding of SFRP1 and COPD 1 0.01 4.47 0
39 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0
40 INT283716 Neurod1 Positive_regulation of Pax6 1 0.23 0.46 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for dorsal/ventral axis specification. They are ordered first by their pain relevance and then by number of times they were reported in dorsal/ventral axis specification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
2 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
3 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
4 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
5 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
6 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
7 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
8 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
9 INT47039 Regulation of SFRP1 14 0.62 7.44 0.92
10 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
11 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
12 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63
13 INT150075 Positive_regulation of Gene_expression of WNT5A 2 0.67 2.53 0.59
14 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
15 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
16 INT135366 Localization of SFRP1 4 0.75 1.82 0.47
17 INT210125 Regulation of Axin1 1 0.02 2.45 0.46
18 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
19 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
20 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
21 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
22 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
23 INT335875 Regulation of Lrp6 1 0.57 0.43 0.27
24 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
25 INT352698 Gene_expression of VAX2 1 0.06 0.85 0.19
26 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
27 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
28 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
29 INT335861 Localization of Lrp6 1 0.69 0.54 0.17
30 INT210123 Localization of Axin1 1 0.04 0.84 0.17
31 INT185254 Gene_expression of Pax6 14 0.72 1.77 0.16
32 INT66933 Binding of AXIN1 6 0.32 1.8 0.16
33 INT263410 Negative_regulation of Axin1 1 0.01 0 0.14
34 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
35 INT162574 Gene_expression of Wnt5a 7 0.47 0.92 0.1
36 INT282594 Localization of WNT5A 2 0.18 0.89 0.1
37 INT233483 Regulation of Gene_expression of Wnt5a 1 0.19 0.33 0.1
38 INT162576 Positive_regulation of Wnt5a 3 0.48 0.71 0.08
39 INT294014 Regulation of AXIN1 3 0.24 1.04 0.08
40 INT145364 Negative_regulation of AXIN1 2 0.33 0.52 0.08
41 INT290078 Regulation of WNT5A 1 0.07 2.3 0.07
42 INT325665 Positive_regulation of Axin2 1 0.36 0.59 0.06
43 INT347118 Binding of Axin2 1 0.32 1.63 0.06
44 INT206866 Positive_regulation of SFRP1 7 0.51 3.97 0.05
45 INT287913 Positive_regulation of Gene_expression of SFRP1 2 0.25 2.12 0.05
46 INT335865 Positive_regulation of Phosphorylation of Lrp6 1 0.64 0.46 0.05
47 INT335862 Phosphorylation of Lrp6 1 0.76 0.37 0.05
48 INT244699 Positive_regulation of AXIN1 1 0.02 0 0.05
49 INT325670 Negative_regulation of Axin2 1 0.31 0.34 0.04
50 INT325666 Regulation of Axin2 1 0.32 0.31 0.04
51 INT325669 Gene_expression of Axin2 4 0.57 1.42 0.03
52 INT206481 Transcription of Pax6 2 0.41 0.19 0.03
53 INT336419 Negative_regulation of Gene_expression of Pax6 1 0.45 0.12 0.03
54 INT226288 Negative_regulation of SFRP1 6 0.43 4.45 0
55 INT76959 Binding of Ctnnb1 2 0.34 0.69 0
56 INT294025 Phosphorylation of AXIN1 2 0.38 0.47 0
57 INT291889 Negative_regulation of Pax6 2 0.45 0.39 0
58 INT205099 Positive_regulation of Gene_expression of AXIN2 1 0.48 3.48 0
59 INT230651 Phosphorylation of Ctnnb1 1 0.10 0 0
60 INT230674 Positive_regulation of Phosphorylation of Ctnnb1 1 0.06 0 0
61 INT326137 Protein_catabolism of Ctnnb1 1 0.02 1.08 0
62 INT287932 Negative_regulation of Binding of AXIN1 1 0.12 0 0
63 INT335872 Positive_regulation of Gene_expression of Lrp6 1 0.46 0.18 0
64 INT355576 Negative_regulation of Negative_regulation of Ctnnb1 1 0.02 1.14 0
65 INT335880 Regulation of Wnt5a 1 0.32 0.07 0
66 INT324196 Positive_regulation of Gene_expression of Pax6 1 0.36 0 0
67 INT205105 Gene_expression of AXIN2 1 0.74 6.6 0
68 INT291888 Regulation of Gene_expression of Pax6 1 0.33 0 0
69 INT220769 Positive_regulation of Positive_regulation of Ctnnb1 1 0.10 0 0
70 INT315189 Binding of SFRP1 1 0.15 2.96 0
71 INT226287 Regulation of Gene_expression of SFRP1 1 0.38 0.37 0
72 INT336416 Binding of Pax6 1 0.28 0 0
73 INT349907 Negative_regulation of Gene_expression of Axin2 1 0.32 0 0
74 INT336420 Positive_regulation of Binding of Pax6 1 0.38 0 0
75 INT347117 Negative_regulation of Binding of Lrp6 1 0.28 0.5 0
76 INT352696 Positive_regulation of VAX2 1 0.05 0.06 0
77 INT291885 Regulation of Pax6 1 0.15 0 0
78 INT335866 Regulation of Transcription of Lrp6 1 0.42 0.25 0
79 INT226286 Negative_regulation of Gene_expression of SFRP1 1 0.31 0.7 0
80 INT162572 Positive_regulation of Gene_expression of Wnt5a 1 0.02 0.3 0
81 INT145371 Negative_regulation of AXIN2 1 0.34 0 0
82 INT294017 Negative_regulation of Localization of SFRP1 1 0.32 0.47 0
83 INT251046 Localization of Axin2 1 0.53 0 0
84 INT335881 Gene_expression of Lrp6 1 0.62 0.09 0
85 INT200852 Positive_regulation of Pax6 1 0.11 0 0
86 INT208927 Localization of Pax6 1 0.11 0 0
87 INT287935 Positive_regulation of Binding of AXIN1 1 0.14 0 0
88 INT335873 Transcription of Lrp6 1 0.64 0.25 0
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