GO:0009967

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Name positive regulation of signal transduction
Categary Process
Go Slim No
Go Link GO:0009967
Unique Molecular Interactions 344
Total Molecular Interactions 515
Total Single Events 4910
Pain Genes Associated 25

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of signal transduction. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73
2 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22
3 INT254243 Binding of HOMER1 and MRI1 1 0.03 1.99 1.57
4 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 0.37 0.17 1.44
5 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
6 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
7 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
8 INT193288 CAP1 Positive_regulation of Pth 1 0.04 0.08 1.14
9 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
10 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
11 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85
12 INT193275 Phax Regulation of Pth 1 0.01 0.16 0.81
13 INT150680 Pomc Negative_regulation of Gene_expression of Eif2ak3 1 0.35 0.07 0.8
14 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
15 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
16 INT299792 Positive_regulation of Binding of CD80 and CTLA4 1 0.17 1.63 0.63
17 INT83424 Binding of CD40LG and ADIPOQ 2 0.13 1 0.59
18 INT83426 ADIPOQ Negative_regulation of Binding of CD40LG 2 0.21 1 0.59
19 INT193289 CAP1 Regulation of Pth 1 0.02 0 0.59
20 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52
21 INT158400 Binding of CD80 and CD86 3 0.36 0.76 0.48
22 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
23 INT149121 Binding of CD80 and Cd28 2 0.04 0.95 0.46
24 INT69637 Binding of CAV1 and Zfp354a 1 0.00 0 0.46
25 INT186673 IL8 Positive_regulation of Positive_regulation of PTH 1 0.01 0.92 0.42
26 INT83423 ADIPOQ Negative_regulation of Binding of IGHG3 1 0.02 0.31 0.42
27 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4
28 INT241679 EIF2AK3 Positive_regulation of Atf4 1 0.06 0.46 0.4
29 INT287819 Binding of CD80 and Cd28 1 0.25 0.7 0.4
30 INT296945 ADIPOQ Negative_regulation of TNF 1 0.03 1.13 0.4
31 INT287818 Negative_regulation of Binding of CD80 and Cd28 1 0.29 0.7 0.4
32 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39
33 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
34 INT240616 Binding of SHBG and ADIPOQ 1 0.31 4.43 0.37
35 INT329449 IL17A Regulation of Gene_expression of Vegfa 1 0.28 0.63 0.36
36 INT99292 Pth Positive_regulation of Jun 1 0.10 0.13 0.36
37 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
38 INT353020 Binding of CD80 and Positive_regulation of Gene_expression of CD28 1 0.13 0.35 0.34
39 INT352232 VEGFA Negative_regulation of Vegfa 1 0.02 0.21 0.34
40 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
41 INT337412 AKT3 Negative_regulation of Localization of AKT2 1 0.09 0.5 0.32
42 INT337418 AKT2 Negative_regulation of Localization of AKT3 1 0.09 0.5 0.32
43 INT329448 IL17A Positive_regulation of Gene_expression of Vegfa 1 0.45 0.59 0.32
44 INT337414 AKT2 Negative_regulation of AKT1 1 0.10 0.5 0.32
45 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3
46 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
47 INT240626 Binding of ADIPOQ and Hdlcl1 1 0.02 3.27 0.28
48 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
49 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
50 INT317773 Positive_regulation of GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
51 INT317775 GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
52 INT16163 Pth Regulation of Gene_expression of Plast4 1 0.00 0.65 0.25
53 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
54 INT130691 CA2 Positive_regulation of EIF2AK3 1 0.16 0.59 0.24
55 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23
56 INT179492 Binding of Ins1 and Adipoq 1 0.16 1.16 0.23
57 INT289959 Negative_regulation of Binding of CD28 and CD80 1 0.07 0.24 0.23
58 INT289953 Binding of CD80 and KLF1 1 0.00 0.21 0.23
59 INT260835 NRP2 Positive_regulation of Eif2ak3 1 0.00 0.73 0.23
60 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
61 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22
62 INT118838 Gene_expression of Vegfa Positive_regulation of Gene_expression of Mb 1 0.44 0.4 0.22
63 INT63192 PTH Positive_regulation of ESR1 1 0.20 0.29 0.22
64 INT63201 PTH Positive_regulation of CD8A 1 0.45 0.29 0.22
65 INT249760 Positive_regulation of Cnr1 Negative_regulation of Gene_expression of Adipoq 1 0.20 0.81 0.22
66 INT260397 Positive_regulation of Hmox1 Positive_regulation of Gene_expression of Adipoq 1 0.37 0.78 0.22
67 INT63200 PTH Positive_regulation of IL2 1 0.24 0.29 0.22
68 INT63194 PTH Positive_regulation of PGR 1 0.25 0.29 0.22
69 INT137611 Crh Positive_regulation of Vegfa 1 0.43 0.49 0.21
70 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
71 INT137612 Crh Positive_regulation of Positive_regulation of Vegfa 1 0.43 0.43 0.21
72 INT114837 Il1b Negative_regulation of Vegfa 1 0.26 3.04 0.21
73 INT242996 Adipoq Negative_regulation of Transcription of Cd68 1 0.22 0.6 0.21
74 INT242994 Adipoq Negative_regulation of Spp1 1 0.19 0.59 0.21
75 INT116466 Vegfa Positive_regulation of Amfr 1 0.07 1.41 0.21
76 INT137610 Crh Positive_regulation of Localization of Vegfa 1 0.43 0.49 0.21
77 INT332304 Binding of Il6 and Adipoq 1 0.03 0.4 0.2
78 INT252366 Binding of RUNX1 and CD80 1 0.01 0.54 0.2
79 INT145886 Binding of CXCL1 and Adipoq 1 0.00 0.77 0.2
80 INT352518 Binding of FAT1 and Adipoq 1 0.01 2.79 0.2
81 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19
82 INT260394 Positive_regulation of Hmox1 Positive_regulation of Adipoq 1 0.37 0.78 0.19
83 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
84 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
85 INT289251 Ptpn11 Regulation of Il6 1 0.09 0.86 0.18
86 INT334394 ADIPOQ Negative_regulation of Gene_expression of Tnf 1 0.37 1.06 0.18
87 INT207186 Binding of Adipoq and Bmi1 1 0.01 1.65 0.18
88 INT330514 Vegfa Positive_regulation of VEGFA 1 0.18 0.5 0.18
89 INT228168 Adipoq Positive_regulation of Prkag1 2 0.05 1.08 0.17
90 INT306261 AKT2 Negative_regulation of Phosphorylation of FOXO1 1 0.25 0.41 0.17
91 INT220520 Ugt1a6b Positive_regulation of Gene_expression of Cav1 1 0.01 0.81 0.17
92 INT293361 Binding of CD80 and KLRD1 1 0.00 0.38 0.16
93 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
94 INT240622 Binding of ADIPOQ and Etv3 1 0.04 1.32 0.15
95 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
96 INT347333 Binding of S100a9 and Vegfa 1 0.38 0.46 0.15
97 INT155644 Binding of CAV1 and HSD11B1 1 0.39 0.77 0.15
98 INT347332 Binding of S100a8 and Vegfa 1 0.38 0.46 0.15
99 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
100 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
101 INT157275 Binding of PRKAA1 and Adipoq 1 0.01 1.13 0.15
102 INT124412 Binding of PTH and Pth 1 0.02 0.65 0.14
103 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14
104 INT309779 PTH Negative_regulation of Gene_expression of COL5A2 1 0.00 0.52 0.14
105 INT157273 Adipoq Positive_regulation of PRKAA1 1 0.03 1.16 0.14
106 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
107 INT312893 Gsk3b Positive_regulation of Hdac6 1 0.07 0.65 0.13
108 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
109 INT270663 Adipoq Positive_regulation of Il6 1 0.02 1.05 0.12
110 INT207109 F2 Positive_regulation of Phosphorylation of Akt2 1 0.08 0.25 0.12
111 INT220527 Nme1 Negative_regulation of Positive_regulation of Vegfa 1 0.00 1.23 0.12
112 INT179493 Adipoq Positive_regulation of Ins1 1 0.20 0.99 0.12
113 INT298471 CD40LG Positive_regulation of CD80 1 0.04 0.33 0.12
114 INT270669 Adipoq Positive_regulation of IL8 1 0.01 1.06 0.12
115 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
116 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
117 INT207112 Sh2b2 Positive_regulation of Phosphorylation of Akt2 1 0.68 0.24 0.12
118 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12
119 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
120 INT207115 Sh2b2 Positive_regulation of Akt2 1 0.49 0.24 0.12
121 INT298473 IL4 Positive_regulation of CD80 1 0.06 0.33 0.12
122 INT270665 Adipoq Positive_regulation of Ccl2 1 0.07 1.06 0.12
123 INT164746 Binding of LEP and Adipoq 1 0.07 0.69 0.12
124 INT228175 RNU1-1 Regulation of Adipoq 1 0.11 0.78 0.12
125 INT114836 Tnf Negative_regulation of Vegfa 1 0.10 1.56 0.11
126 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11
127 INT257467 Fat1 Regulation of Gene_expression of Adipoq 1 0.08 0.56 0.11
128 INT93535 PTH Negative_regulation of Gene_expression of Tnfsf11 1 0.19 0.22 0.11
129 INT352751 Pkd2 Regulation of Localization of Vegfa 1 0.11 0.47 0.1
130 INT240624 Binding of ADIPOQ and Hdl1 1 0.02 0.85 0.1
131 INT220517 Negative_regulation of Ugt1a6b Positive_regulation of Cav1 1 0.01 0.35 0.1
132 INT352750 Pkd2 Positive_regulation of Vegfa 1 0.20 0.47 0.1
133 INT262996 ADIPOQ Regulation of INS 1 0.13 1.25 0.1
134 INT309780 Binding of PTH and PTH1R 3 0.12 0.3 0.09
135 INT310275 Negative_regulation of Binding of Adipoq and Ins1 1 0.19 1.14 0.09
136 INT274156 Negative_regulation of Cabin1 Negative_regulation of Gene_expression of Vegfa 1 0.08 0.28 0.09
137 INT157276 PPARG Positive_regulation of Adipoq 1 0.29 1.09 0.09
138 INT351032 Binding of CD80 and CD96 1 0.01 0.36 0.09
139 INT302977 Binding of Cav1 and Smpd2 1 0.08 0.71 0.09
140 INT157274 Adipoq Positive_regulation of ADIPOR1 1 0.00 1.2 0.09
141 INT220511 Cav1 Negative_regulation of Transcription of Ccnd1 1 0.03 0.83 0.09
142 INT310274 Binding of Adipoq and Ins1 1 0.21 1.14 0.09
143 INT215884 Eif2ak3 Positive_regulation of Gene_expression of Musd1 1 0.01 0.96 0.09
144 INT228174 RNU1-1 Positive_regulation of Gene_expression of Adipoq 1 0.12 0.55 0.08
145 INT330955 HOMER1 Positive_regulation of Gene_expression of VDR 1 0.01 0.99 0.08
146 INT337888 Ins1 Positive_regulation of Gene_expression of Ldlrap1 1 0.06 0 0.08
147 INT257466 Psd Negative_regulation of Gene_expression of Adipoq 1 0.22 0.66 0.08
148 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
149 INT345370 Binding of Vegfa and Insrr 1 0.01 2.29 0.08
150 INT267154 ADIPOQ Regulation of Positive_regulation of SUGT1 1 0.03 1.18 0.08
151 INT337889 Binding of Ins1 and Ldlrap1 1 0.06 0.27 0.08
152 INT352517 Binding of INS and Adipoq 1 0.09 1.32 0.07
153 INT291837 Binding of Pecam1 and Vegfa 1 0.09 1.1 0.07
154 INT262997 Binding of HSD11B1 and ADIPOQ 1 0.54 2.82 0.07
155 INT260392 Hmox1 Positive_regulation of Adipoq 1 0.32 0.65 0.07
156 INT336380 Gene_expression of Adipoq Positive_regulation of Ppara 1 0.06 1.77 0.07
157 INT215874 Positive_regulation of Eif2ak3 Positive_regulation of Positive_regulation of Ddit3 1 0.47 0.31 0.07
158 INT215883 Eif2ak3 Regulation of Musd1 1 0.00 0.8 0.06
159 INT215878 Eif2ak3 Positive_regulation of Localization of Ins1 1 0.04 0.96 0.06
160 INT215877 Atf4 Regulation of Eif2ak3 1 0.44 0.21 0.06
161 INT140813 Binding of Retn and Adipoq 1 0.03 1.18 0.06
162 INT215873 Ddit3 Regulation of Eif2ak3 1 0.39 0.2 0.06
163 INT251803 PTH1R Positive_regulation of PTH 1 0.08 0.06 0.05
164 INT183853 Gene_expression of CAV1 Negative_regulation of Positive_regulation of MAPK1 1 0.28 0.25 0.05
165 INT107888 PTH Positive_regulation of PTH2 1 0.20 0 0.05
166 INT339778 Binding of EDNRA and PTH 1 0.12 0.35 0.05
167 INT267157 LEP Positive_regulation of ADIPOQ 1 0.10 0.51 0.05
168 INT355439 Pdia3 Regulation of Gene_expression of Eif2ak3 1 0.01 0.83 0.05
169 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05
170 INT228169 Gm2733 Regulation of Adipoq 1 0.00 0.51 0.05
171 INT295337 Egf Positive_regulation of Ptpn11 1 0.15 0.08 0.05
172 INT235640 Binding of GATA3 and Mrgpre 1 0.01 0.8 0.04
173 INT182775 Binding of PTH and ROS1 1 0.04 1.73 0.04
174 INT342581 Binding of Dbp and Pth 1 0.04 2.12 0.04
175 INT354971 Binding of HOMER1 and Shank1 1 0.01 0 0.04
176 INT5608 Gnl3 Regulation of Eif2ak3 1 0.05 0 0.04
177 INT244464 EIF2AK3 Positive_regulation of Positive_regulation of EIF2S2 1 0.17 0.37 0.04
178 INT244463 EIF2AK3 Regulation of Phosphorylation of EIF2S2 1 0.09 0.37 0.04
179 INT228591 Adipoq Positive_regulation of Phosphorylation of Prkaa2 1 0.31 0.61 0.04
180 INT269759 PTH Positive_regulation of DMD 2 0.06 0.37 0.03
181 INT236590 Binding of Adipoq and Ncoa2 1 0.15 0.2 0.03
182 INT236587 Binding of Adipoq and Ncoa1 1 0.17 0.2 0.03
183 INT316598 Pth Regulation of Fgf23 1 0.10 0.28 0.03
184 INT220512 Cav1 Regulation of Positive_regulation of Cdkn1b 1 0.06 0.85 0.03
185 INT274288 AGT Positive_regulation of Gene_expression of Vegfa 1 0.07 0.98 0.03
186 INT270775 PTH Regulation of DMD 1 0.09 0.64 0.03
187 INT256707 Eif2ak3 Regulation of Gene_expression of Wfs1 1 0.10 0.78 0.03
188 INT314370 Adipoq Positive_regulation of Tnfrsf11a 1 0.04 1.26 0.03
189 INT270776 PTH Regulation of Negative_regulation of DMD 1 0.09 0.3 0.03
190 INT236592 Positive_regulation of Binding of Adipoq and Ncoa2 1 0.19 0.2 0.03
191 INT300445 VEGFA Positive_regulation of Vegfa 1 0.03 1.33 0.03
192 INT295349 Binding of Ptpn11 and Grb7 1 0.13 0.11 0.03
193 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03
194 INT257590 Pth Positive_regulation of DMD 2 0.02 0.44 0
195 INT302311 PTH Negative_regulation of Gene_expression of SOST 1 0.29 0.59 0
196 INT174532 PTH Positive_regulation of Transcription of IGF1 1 0.06 0.51 0
197 INT284392 Binding of ABCA1 and Vegfa 1 0.00 0.71 0
198 INT146806 Tnfrsf11b Positive_regulation of Pth 1 0.46 1.43 0
199 INT295338 Ptpn11 Regulation of Binding of Xpo1 1 0.02 0 0
200 INT346522 Binding of MCL1 and PTH 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of signal transduction. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54
2 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26
3 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
4 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
5 INT109031 Positive_regulation of Eif2ak3 44 0.69 21.11 14.72
6 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
7 INT109034 Gene_expression of Eif2ak3 37 0.77 17.11 14.19
8 INT132178 Binding of CD80 41 0.47 15.55 12.98
9 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
10 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
11 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7
12 INT150678 Positive_regulation of Gene_expression of Eif2ak3 17 0.69 6.64 8.99
13 INT22083 Regulation of Pth 55 0.62 22.32 8.9
14 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24
15 INT93914 Gene_expression of CD80 70 0.75 36.35 7.74
16 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
17 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
18 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33
19 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
20 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
21 INT36757 Gene_expression of Eif2ak3 4 0.74 0.15 6.06
22 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
23 INT100991 Gene_expression of HOMER1 12 0.67 6.96 4.98
24 INT62570 Binding of Pth 48 0.48 26.45 4.85
25 INT137336 Phosphorylation of Eif2ak3 14 0.79 4.72 4.78
26 INT4097 Localization of Pth 66 0.81 47.17 4.36
27 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
28 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
29 INT5602 Positive_regulation of Eif2ak3 9 0.66 0 4.04
30 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
31 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
32 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
33 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
34 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67
35 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58
36 INT3824 Negative_regulation of PTH 40 0.59 28.58 3.39
37 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1
38 INT28094 Binding of PTH 29 0.37 13.57 3.09
39 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
40 INT200670 Gene_expression of AKT2 25 0.75 16.25 3
41 INT133080 Gene_expression of GATA3 15 0.61 5.64 2.89
42 INT22500 Negative_regulation of Pth 6 0.43 3.41 2.83
43 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
44 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
45 INT204340 Localization of ADIPOQ 20 0.75 25.18 2.64
46 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
47 INT26974 Negative_regulation of Adipoq 27 0.52 26.01 2.59
48 INT203819 Binding of Eif2ak3 9 0.37 5.94 2.57
49 INT15695 Positive_regulation of EIF2AK3 12 0.67 7.01 2.56
50 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47
51 INT22715 Positive_regulation of Gene_expression of Pth 29 0.64 22.53 2.31
52 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
53 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
54 INT122561 Negative_regulation of Gene_expression of Adipoq 12 0.56 14.02 2.26
55 INT135451 Positive_regulation of Positive_regulation of Adipoq 3 0.40 2.06 2.24
56 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
57 INT2544 Localization of PTH 39 0.81 30.55 2.22
58 INT36758 Positive_regulation of Gene_expression of Eif2ak3 1 0.48 0 2.21
59 INT97134 Negative_regulation of CD80 8 0.57 5.09 2.11
60 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
61 INT138029 Binding of Adipoq 10 0.40 6.81 2.04
62 INT134633 Localization of Adipoq 9 0.60 6.39 2.03
63 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
64 INT36755 Positive_regulation of Localization of Eif2ak3 1 0.48 0 1.97
65 INT36756 Localization of Eif2ak3 1 0.71 0 1.96
66 INT150675 Regulation of Gene_expression of Eif2ak3 3 0.40 1.11 1.93
67 INT93912 Positive_regulation of CD80 11 0.56 7.01 1.88
68 INT36759 Regulation of Gene_expression of Eif2ak3 1 0.59 0 1.74
69 INT147636 Regulation of CD80 3 0.60 1.27 1.73
70 INT227273 Localization of Adipoq 22 0.72 18.04 1.72
71 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
72 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
73 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
74 INT3343 Regulation of PTH 24 0.62 11.18 1.62
75 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
76 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
77 INT209896 Positive_regulation of Gene_expression of CD80 19 0.49 11.9 1.59
78 INT109033 Positive_regulation of Positive_regulation of Eif2ak3 2 0.45 2.36 1.59
79 INT209959 Negative_regulation of Binding of CD80 3 0.42 0.9 1.52
80 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47
81 INT150677 Negative_regulation of Eif2ak3 9 0.58 6.24 1.46
82 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
83 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
84 INT116008 Binding of Gata3 2 0.34 1.37 1.41
85 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
86 INT6514 Positive_regulation of Gene_expression of PTH 28 0.67 30.28 1.37
87 INT215864 Localization of Eif2ak3 5 0.75 3.26 1.36
88 INT18337 Transcription of Eif2ak3 3 0.68 0 1.36
89 INT39500 Positive_regulation of Positive_regulation of Pth 14 0.48 9.75 1.28
90 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
91 INT141862 Binding of Cav1 11 0.36 1.32 1.25
92 INT22498 Binding of Pth 2 0.48 2.81 1.24
93 INT127900 Phosphorylation of EIF2AK3 14 0.80 7.99 1.22
94 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
95 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
96 INT160054 Localization of AKT2 4 0.73 1.93 1.18
97 INT227275 Negative_regulation of Gene_expression of Adipoq 19 0.53 19.51 1.15
98 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14
99 INT139764 Negative_regulation of CAV1 10 0.58 6.57 1.14
100 INT72749 Regulation of Pth 4 0.62 1.39 1.14
101 INT82214 Transcription of PTH 6 0.54 3.33 1.11
102 INT133079 Positive_regulation of Gene_expression of GATA3 3 0.50 1.03 1.11
103 INT137338 Regulation of Eif2ak3 8 0.45 5.5 1.07
104 INT100992 Regulation of Gene_expression of HOMER1 2 0.10 0.74 1.06
105 INT23030 Positive_regulation of Pth 13 0.61 9.24 0.97
106 INT136613 Negative_regulation of Cav1 2 0.57 2.28 0.96
107 INT4096 Regulation of Localization of Pth 7 0.58 3.97 0.95
108 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92
109 INT160140 Regulation of Binding of Adipoq 1 0.37 0.87 0.92
110 INT160056 Positive_regulation of AKT2 3 0.48 1.43 0.88
111 INT141442 Negative_regulation of Phosphorylation of Cav1 1 0.59 0.94 0.87
112 INT240368 Positive_regulation of Localization of Eif2ak3 1 0.34 0.66 0.87
113 INT271605 Regulation of Gene_expression of AKT2 1 0.44 0.81 0.87
114 INT227270 Regulation of Gene_expression of Adipoq 5 0.55 7.35 0.85
115 INT109032 Negative_regulation of Positive_regulation of Eif2ak3 1 0.38 0.94 0.85
116 INT151927 Regulation of Gene_expression of Adipoq 3 0.43 3.32 0.81
117 INT127899 Gene_expression of EIF2AK3 8 0.75 2.89 0.8
118 INT154053 Negative_regulation of Gene_expression of Eif2ak3 2 0.43 1.28 0.79
119 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78
120 INT142013 Positive_regulation of Regulation of Adipoq 1 0.03 0.65 0.78
121 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77
122 INT28020 Binding of Adipoq 10 0.36 11.49 0.77
123 INT127901 Positive_regulation of Gene_expression of EIF2AK3 3 0.49 1.8 0.77
124 INT112088 Regulation of Cav1 2 0.44 0.51 0.73
125 INT200669 Negative_regulation of AKT2 2 0.42 0.94 0.72
126 INT12443 Regulation of Localization of Vegfa 2 0.20 0 0.72
127 INT42722 Negative_regulation of Ptpn11 1 0.21 0 0.71
128 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
129 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
130 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
131 INT153667 Localization of CAV1 15 0.76 11.92 0.68
132 INT148756 Regulation of Adipoq 10 0.60 7.83 0.67
133 INT127898 Positive_regulation of Phosphorylation of EIF2AK3 3 0.49 2.03 0.67
134 INT254244 Localization of HOMER1 1 0.19 0.68 0.66
135 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
136 INT340625 Protein_catabolism of Vegfa 1 0.05 1.61 0.64
137 INT17840 Negative_regulation of GATA3 3 0.41 1.96 0.63
138 INT312882 Negative_regulation of Hdac6 1 0.52 1.86 0.63
139 INT62067 Negative_regulation of Gene_expression of Pth 13 0.41 8.24 0.61
140 INT86700 Regulation of Cav1 7 0.54 0.92 0.61
141 INT205470 Positive_regulation of GATA3 4 0.33 2.53 0.61
142 INT118310 Negative_regulation of Positive_regulation of Adipoq 2 0.34 2.47 0.61
143 INT179488 Positive_regulation of Transcription of Adipoq 3 0.37 0.5 0.6
144 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
145 INT131001 Regulation of CAV1 6 0.44 3.77 0.59
146 INT141863 Negative_regulation of Gene_expression of Cav1 4 0.49 1.77 0.58
147 INT226481 Negative_regulation of Gene_expression of GATA3 1 0.06 1.41 0.57
148 INT19395 Negative_regulation of Localization of Pth 11 0.58 10.16 0.55
149 INT144053 Transcription of GATA3 1 0.67 0.89 0.54
150 INT172964 Binding of Vegfa 14 0.47 10.62 0.53
151 INT147635 Regulation of Positive_regulation of CD80 1 0.44 0.38 0.53
152 INT5601 Regulation of Eif2ak3 1 0.43 0 0.53
153 INT105677 Binding of Vegfa 7 0.37 5.22 0.51
154 INT147456 Negative_regulation of Positive_regulation of CD80 2 0.41 1.32 0.5
155 INT227272 Transcription of Adipoq 8 0.64 8.29 0.49
156 INT83430 Positive_regulation of Binding of ADIPOQ 2 0.21 0.85 0.49
157 INT18336 Positive_regulation of Positive_regulation of Eif2ak3 1 0.33 0 0.49
158 INT86702 Localization of Cav1 8 0.69 0.76 0.47
159 INT271604 Positive_regulation of Gene_expression of AKT2 2 0.49 0.22 0.47
160 INT299799 Negative_regulation of Negative_regulation of GATA3 1 0.09 1.32 0.47
161 INT36770 Positive_regulation of Localization of Pth 14 0.70 10.42 0.46
162 INT153672 Negative_regulation of Negative_regulation of CAV1 1 0.25 0.2 0.46
163 INT192808 Negative_regulation of Localization of PTH 6 0.59 7.31 0.45
164 INT83434 Negative_regulation of Binding of ADIPOQ 1 0.39 1.14 0.45
165 INT103825 Regulation of Binding of Pth 1 0.27 0.63 0.45
166 INT220504 Positive_regulation of Gene_expression of Cav1 11 0.39 6.26 0.43
167 INT166240 Regulation of Gene_expression of Cav1 3 0.51 1.03 0.43
168 INT268877 Regulation of Gene_expression of Vegfa 2 0.58 4.73 0.42
169 INT152023 Regulation of Vegfa 4 0.52 3.99 0.41
170 INT43720 Regulation of Positive_regulation of Vegfa 1 0.03 0.41 0.41
171 INT43722 Positive_regulation of Regulation of Vegfa 1 0.06 0.41 0.41
172 INT46615 Negative_regulation of Gene_expression of PTH 8 0.57 5.1 0.4
173 INT308980 Positive_regulation of Negative_regulation of Adipoq 3 0.33 2.3 0.4
174 INT15696 Regulation of EIF2AK3 2 0.26 1.1 0.39
175 INT129849 Positive_regulation of Localization of Vegfa 1 0.46 0.35 0.39
176 INT220506 Binding of Cav1 13 0.45 5.46 0.38
177 INT58566 Regulation of Gene_expression of Pth 5 0.58 2.3 0.38
178 INT39911 Negative_regulation of Positive_regulation of Pth 5 0.41 2.57 0.37
179 INT135953 Negative_regulation of Positive_regulation of Cav1 2 0.37 1.09 0.37
180 INT186677 Protein_catabolism of PTH 2 0.33 1.49 0.37
181 INT163277 Negative_regulation of Gene_expression of CAV1 17 0.56 10.77 0.35
182 INT243089 Gene_expression of Ldlrap1 2 0.65 0.14 0.35
183 INT97137 Negative_regulation of Gene_expression of CD80 7 0.33 3.39 0.34
184 INT42244 Regulation of Gene_expression of PTH 5 0.45 3.95 0.34
185 INT15697 Negative_regulation of EIF2AK3 1 0.41 0 0.33
186 INT179491 Transcription of Adipoq 4 0.51 0.98 0.32
187 INT15698 Transcription of EIF2AK3 1 0.52 0 0.32
188 INT86669 Positive_regulation of HOMER1 2 0.30 1.37 0.31
189 INT323118 Positive_regulation of Localization of AKT2 2 0.49 0.48 0.31
190 INT227268 Negative_regulation of Transcription of Adipoq 4 0.52 4.93 0.3
191 INT185181 Phosphorylation of Pth 2 0.64 1.51 0.3
192 INT127902 Negative_regulation of Gene_expression of EIF2AK3 1 0.42 0.47 0.3
193 INT125804 Localization of Pth 9 0.69 3.93 0.29
194 INT141867 Positive_regulation of Transcription of Cav1 2 0.52 0.46 0.29
195 INT141868 Transcription of Cav1 2 0.54 1.48 0.29
196 INT312879 Regulation of Hdac6 1 0.55 0.76 0.29
197 INT141861 Negative_regulation of Binding of Cav1 1 0.44 0.4 0.29
198 INT224619 Regulation of Positive_regulation of Vegfa 1 0.05 0.57 0.27
199 INT224638 Positive_regulation of Positive_regulation of Vegfa 1 0.06 0.57 0.27
200 INT207096 Phosphorylation of Akt2 1 0.72 0.51 0.27
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