GO:0010008

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Name endosome membrane
Categary Component
Go Slim No
Go Link GO:0010008
Unique Molecular Interactions 925
Total Molecular Interactions 1268
Total Single Events 11857
Pain Genes Associated 81

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for endosome membrane. They are ordered first by their pain relevance and then by number of times they were reported for endosome membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
2 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
3 INT269444 Binding of RAB5A and HHIP 1 0.04 0 5.79
4 INT164362 Binding of NLRP1 and VTA1 1 0.15 2.37 4.67
5 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64
6 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
7 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37
8 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
9 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
10 INT110525 Binding of MC1R and OCA2 1 0.41 1.08 1.97
11 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79
12 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5
13 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42
14 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
15 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
16 INT21857 Maoa Regulation of Ap3d1 1 0.12 0.18 1.23
17 INT164365 Positive_regulation of Binding of NLRP1 and VTA1 1 0.14 0.6 1.21
18 INT281373 Tcf21 Regulation of Fig4 1 0.03 0.67 1.2
19 INT281383 FSCN1 Positive_regulation of Fig4 1 0.02 0.44 1.19
20 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
21 INT59203 ecs Positive_regulation of Negative_regulation of Ube2d3 1 0.00 1.93 1.15
22 INT69874 POMC Negative_regulation of TYRP1 1 0.13 0 1.07
23 INT69871 ASIP Negative_regulation of TYRP1 1 0.36 0 1.07
24 INT269443 Positive_regulation of Binding of RAB5A and HHIP 1 0.04 0 1.06
25 INT243494 Binding of Vta1 and LOC308670 1 0.01 0.06 1.06
26 INT214875 Ap3d1 Negative_regulation of Gene_expression of Fos 1 0.00 0.39 1.04
27 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
28 INT255335 Fig4 Regulation of Phosphorylation of Nav1 1 0.01 0 1.03
29 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
30 INT265649 TBK1 Negative_regulation of COMT 1 0.01 0.61 0.94
31 INT216736 Binding of ADORA2B and ATP6V0A1 2 0.08 0.06 0.93
32 INT72386 Egf Positive_regulation of Phosphorylation of Shc1 1 0.09 0.18 0.93
33 INT147507 Binding of Ret and Gtf3a 1 0.03 0.81 0.92
34 INT147505 Binding of Ret and Gdnf 1 0.27 0.81 0.92
35 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
36 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
37 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
38 INT354522 Binding of HBG2 and Wipi1 1 0.00 2.64 0.87
39 INT164363 Regulation of Binding of NLRP1 and VTA1 1 0.14 0.45 0.86
40 INT261479 Fig4 Positive_regulation of Ephb1 1 0.07 0.79 0.83
41 INT269455 Binding of RAB5A and GOPC 1 0.08 0 0.82
42 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
43 INT209043 Binding of Fn1 and Slc11a1 3 0.03 1.91 0.78
44 INT239638 Sst Regulation of Fig4 1 0.12 0.39 0.78
45 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78
46 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78
47 INT215630 Fig4 Regulation of Npy 1 0.01 0.26 0.76
48 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
49 INT202909 Binding of Tacr1 and Fig4 1 0.03 0.33 0.74
50 INT44503 Cubn Positive_regulation of Prl 1 0.18 0 0.74
51 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
52 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
53 INT278812 PYCARD Positive_regulation of VTA1 1 0.09 0.11 0.71
54 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69
55 INT161186 Bdnf Regulation of Gene_expression of Ntrk2 1 0.44 1.05 0.68
56 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68
57 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
58 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67
59 INT161184 NMS Positive_regulation of Gene_expression of Ntrk2 1 0.55 1.3 0.67
60 INT169213 Binding of EGFR and CARTPT 1 0.00 0.22 0.67
61 INT211915 Fig4 Positive_regulation of Mapk3 1 0.12 0.25 0.66
62 INT211916 Fig4 Positive_regulation of Mapk1 1 0.13 0.25 0.66
63 INT246336 Fig4 Regulation of Localization of Nts 1 0.18 0 0.66
64 INT222253 Binding of Cxcl10 and Fig4 1 0.09 0.66 0.65
65 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
66 INT338390 Thim Regulation of Gene_expression of Ret 1 0.02 0.43 0.65
67 INT313703 Binding of Calca and Fig4 1 0.11 0 0.65
68 INT110526 OCA2 Regulation of MC1R 1 0.49 0.43 0.65
69 INT209063 Slc11a1 Positive_regulation of Il17a 1 0.11 0.4 0.65
70 INT114845 RET Regulation of Gene_expression of Lgals1 1 0.02 0.84 0.65
71 INT30130 Binding of TYRP1 and Gast 1 0.06 0.09 0.63
72 INT144107 Binding of SLC6A2 and SLC6A4 1 0.00 0.18 0.62
73 INT326471 Binding of ATP6V0A1 and IGKV2D-29 1 0.00 0.09 0.62
74 INT182819 Binding of CD63 and PECAM1 1 0.00 1.63 0.61
75 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61
76 INT284089 Binding of NTRK2 and SERPINE1 1 0.27 0.73 0.61
77 INT90119 Ntrk2 Regulation of Gene_expression of Nfkb1 1 0.01 0.27 0.6
78 INT79740 Ntf3 Regulation of Positive_regulation of Ntrk2 1 0.28 0 0.6
79 INT59202 ecs Positive_regulation of Ube2d3 1 0.00 0.98 0.59
80 INT197050 Binding of HLA-DOA and HLA-E 2 0.08 1.73 0.58
81 INT280895 Runx1 Positive_regulation of Gene_expression of Ret 2 0.33 0.2 0.58
82 INT98034 Binding of Ret and Trpv1 1 0.43 0.42 0.58
83 INT169286 CNR1 Positive_regulation of Phosphorylation of EGFR 1 0.45 0.18 0.57
84 INT90115 Ntrk2 Regulation of Jun 1 0.01 0.27 0.57
85 INT39210 TF Positive_regulation of Gene_expression of IL2 1 0.17 0.07 0.57
86 INT263975 NR4A3 Negative_regulation of Positive_regulation of TBK1 1 0.02 1.2 0.57
87 INT281378 FSCN1 Positive_regulation of Gene_expression of Fig4 1 0.02 0.22 0.56
88 INT261481 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.02 0.21 0.56
89 INT281648 Negative_regulation of Binding of Trpv1 and Fig4 1 0.14 0.69 0.55
90 INT222252 Positive_regulation of Binding of Ccr2 and Fig4 1 0.16 0.67 0.55
91 INT281647 Binding of Trpv1 and Fig4 1 0.12 0.68 0.55
92 INT222245 Binding of Ccr2 and Fig4 1 0.12 0.67 0.55
93 INT72387 Trim13 Regulation of Phosphorylation of Shc1 1 0.32 0.09 0.54
94 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
95 INT208984 Binding of Ca2 and Fig4 1 0.02 0 0.54
96 INT269449 Positive_regulation of Binding of RAB5A and GOPC 1 0.11 0 0.53
97 INT128431 SLC6A4 Regulation of S100A4 1 0.48 0.65 0.53
98 INT242613 Binding of Gfra2 and Ret 1 0.02 0 0.52
99 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52
100 INT47745 Binding of Slc6a4 and Htr2a 1 0.33 0.09 0.52
101 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52
102 INT193554 Ntrk2 Positive_regulation of Positive_regulation of Ephb1 1 0.01 0.73 0.52
103 INT127337 Crh Regulation of LOC308670 1 0.01 0 0.51
104 INT334901 LDLR Positive_regulation of Crp 1 0.00 1.48 0.51
105 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51
106 INT134533 Binding of Ntrk2 and Psds1 1 0.01 0 0.5
107 INT220741 Binding of EGFR and SOAT1 1 0.02 0.37 0.49
108 INT160445 Tpsab1 Positive_regulation of Gene_expression of SPG21 1 0.48 0.96 0.48
109 INT135588 Positive_regulation of IKBKE Positive_regulation of NFKB1 1 0.18 1.29 0.48
110 INT135587 IKBKE Positive_regulation of NFKB1 1 0.18 1.28 0.48
111 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48
112 INT132445 TF Positive_regulation of IL8 1 0.11 2.23 0.46
113 INT69638 Binding of TF and Zfp354a 1 0.00 0 0.46
114 INT242628 Binding of Gfra1 and Ret 1 0.03 0 0.46
115 INT242615 Ret Positive_regulation of Gene_expression of Gfra1 1 0.04 0 0.46
116 INT242596 Binding of Ntrk1 and Ret 1 0.12 0 0.46
117 INT128043 Positive_regulation of Ntrk2 Positive_regulation of Phosphorylation of Trib3 1 0.07 0.34 0.45
118 INT341211 Gopc Regulation of Shc1 1 0.02 0.68 0.45
119 INT84517 IRF6 Positive_regulation of TF 1 0.14 0.19 0.44
120 INT113248 Olr1259 Negative_regulation of Slc6a4 1 0.00 0.23 0.44
121 INT209049 Slc11a1 Positive_regulation of Localization of Il12a 1 0.04 0.09 0.44
122 INT304281 IL8 Positive_regulation of TBK1 1 0.01 2.35 0.44
123 INT154592 Binding of Ntrk2 and Positive_regulation of Gene_expression of Kcna3 1 0.11 0.16 0.44
124 INT157343 Binding of AQP4 and HLA-DPB1 1 0.30 0.89 0.43
125 INT232293 Abat Regulation of Binding of Fig4 1 0.11 0 0.43
126 INT174501 Binding of HLA-B and HLA-DOA 2 0.03 1.84 0.42
127 INT228323 PYCARD Positive_regulation of FIG4 1 0.17 0 0.42
128 INT269448 HHIP Positive_regulation of Binding of RAB5A 1 0.04 0 0.42
129 INT261790 SHC1 Positive_regulation of Slc12a5 1 0.02 0.06 0.41
130 INT84516 NFKB1 Positive_regulation of Gene_expression of TF 1 0.10 0.09 0.41
131 INT84518 IRF6 Positive_regulation of Gene_expression of TF 1 0.14 0.09 0.41
132 INT58480 Agpat1 Regulation of TF 1 0.00 0.46 0.4
133 INT58481 Crp Regulation of TF 1 0.01 0.46 0.4
134 INT38269 Binding of TCN1 and CUBN 1 0.00 0.28 0.4
135 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4
136 INT330598 Binding of Il6 and Fig4 1 0.11 1.78 0.4
137 INT232292 Abat Positive_regulation of Fig4 1 0.12 0 0.4
138 INT215629 Binding of Kcnj5 and Fig4 1 0.00 0.37 0.39
139 INT242607 Negative_regulation of Ntrk1 Positive_regulation of Ret 1 0.16 0 0.39
140 INT303444 Timp1 Regulation of Fig4 1 0.15 0.43 0.39
141 INT321292 Fig4 Negative_regulation of Pck1 1 0.10 0.33 0.39
142 INT321301 Fig4 Negative_regulation of G6pc 1 0.07 0.33 0.39
143 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
144 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38
145 INT201485 Ntrk2 Positive_regulation of Prkcg 1 0.01 0.73 0.38
146 INT266553 Ppp2r1a Positive_regulation of Fig4 1 0.00 0 0.38
147 INT266530 Ppyr1 Positive_regulation of Fig4 1 0.01 0 0.38
148 INT272751 EGFR Regulation of Negative_regulation of Prkca 1 0.01 0 0.38
149 INT269456 RAB5A Regulation of Binding of HHIP 1 0.04 0 0.38
150 INT215655 Fig4 Regulation of REG1A 1 0.00 0.13 0.38
151 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
152 INT216738 Binding of ATP6V0A1 and TCFL5 1 0.01 0.06 0.38
153 INT84521 Binding of F7 and TF 1 0.06 0.09 0.37
154 INT154782 Binding of SLC6A4 and Ndst2 1 0.01 0 0.37
155 INT209047 Slc11a1 Positive_regulation of Localization of Il10 1 0.10 0.52 0.36
156 INT223470 Ret Regulation of Ntrk1 1 0.21 0 0.36
157 INT336573 Ptpn2 Regulation of INSR 1 0.00 1.36 0.36
158 INT272412 VSX1 Positive_regulation of Gene_expression of Slc11a1 1 0.00 0.57 0.35
159 INT129293 OPRM1 Positive_regulation of Phosphorylation of IKBKE 1 0.05 0.28 0.35
160 INT242403 INSR Positive_regulation of Gene_expression of Bdkrb1 1 0.45 0.88 0.35
161 INT148240 Binding of Kit and Ret 1 0.24 0.44 0.35
162 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34
163 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34
164 INT177426 Izumo1 Positive_regulation of Positive_regulation of Fig4 1 0.16 0.59 0.34
165 INT257746 SHC1 Positive_regulation of Positive_regulation of PIK3CA 1 0.26 1.04 0.34
166 INT140667 IFNG Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
167 INT46145 HLA-DQA1 Negative_regulation of TAC1 1 0.04 0.09 0.34
168 INT183782 INS Negative_regulation of Gene_expression of TBK1 1 0.01 1.81 0.34
169 INT140666 TNF Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
170 INT53127 Binding of Ntrk2 and Ntf4 1 0.12 0 0.33
171 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32
172 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32
173 INT137160 TLR7 Positive_regulation of Gene_expression of CXCR3 1 0.35 0.34 0.32
174 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32
175 INT257743 Binding of PIK3CA and SHC1 1 0.21 1.03 0.31
176 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31
177 INT100725 TNF Positive_regulation of Localization of SPG21 1 0.28 0.66 0.31
178 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31
179 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31
180 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31
181 INT341777 SLC6A4 Regulation of EPHB1 1 0.02 0.96 0.3
182 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
183 INT245563 Negative_regulation of Runx1 Regulation of Ret 1 0.39 0.76 0.29
184 INT137159 Binding of TLR7 and TLR9 1 0.27 0.33 0.29
185 INT137163 Binding of TLR5 and TLR9 1 0.25 0.33 0.29
186 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
187 INT244422 Binding of DST and Fig4 1 0.01 0.42 0.29
188 INT245556 Runx1 Regulation of Ret 1 0.56 0.76 0.29
189 INT137169 Binding of TLR5 and TLR7 1 0.25 0.33 0.29
190 INT185799 Binding of EGFR and SPP1 1 0.19 0.64 0.29
191 INT252033 Binding of HLA-DQA2 and KLRD1 1 0.00 0.54 0.29
192 INT258861 Binding of HLA-DOA and HLA-DRB1 2 0.14 1.88 0.28
193 INT166093 Negative_regulation of ROS1 Negative_regulation of Positive_regulation of EGFR 1 0.12 0.33 0.28
194 INT291383 Fig4 Regulation of Gene_expression of Cntf 1 0.10 0 0.28
195 INT144434 Gene_expression of Erbb2 Positive_regulation of ras 1 0.16 0.6 0.28
196 INT257744 Binding of PIK3R2 and SHC1 1 0.08 0.96 0.28
197 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
198 INT323710 TRAF6 Regulation of MIR146A 1 0.06 0.55 0.28
199 INT179425 Fig4 Regulation of Creb1 1 0.02 0.32 0.28
200 INT179423 Fig4 Regulation of Mapk3 1 0.02 0.32 0.28

Single Events

The table below shows the top 100 pain related interactions that have been reported for endosome membrane. They are ordered first by their pain relevance and then by number of times they were reported in endosome membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32
2 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81
3 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
4 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92
5 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68
6 INT177581 Regulation of Fig4 113 0.41 39.26 27.75
7 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
8 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
9 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
10 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
11 INT171820 Localization of Fig4 144 0.65 27.38 20.88
12 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59
13 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
14 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
15 INT170033 Positive_regulation of Gene_expression of Fig4 59 0.43 20.99 16.69
16 INT32648 Gene_expression of Tyrp1 80 0.66 17.9 16.59
17 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
18 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32
19 INT65172 Negative_regulation of Ntrk2 35 0.59 9.89 13.08
20 INT174844 Binding of Fig4 81 0.41 18.03 12.87
21 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23
22 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55
23 INT173272 Phosphorylation of Fig4 45 0.48 13.85 11.42
24 INT13240 Gene_expression of TF 94 0.76 57.81 10.99
25 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89
26 INT85631 Positive_regulation of Tyrp1 40 0.64 18.73 10.84
27 INT66303 Regulation of Slc6a4 10 0.45 4.82 10.55
28 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43
29 INT47744 Binding of Slc6a4 21 0.48 5.52 9.45
30 INT8249 Positive_regulation of Cubn 15 0.66 4.05 9.35
31 INT13893 Negative_regulation of Cubn 9 0.36 1.78 9.24
32 INT64849 Gene_expression of Ret 24 0.75 14.36 9.1
33 INT182137 Gene_expression of TLR9 137 0.78 48.48 9.05
34 INT6499 Localization of Ntrk2 44 0.79 11.78 8.75
35 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66
36 INT47682 Transcription of Ntrk2 19 0.69 6.32 8.6
37 INT164368 Localization of VTA1 5 0.53 3.33 8.47
38 INT54368 Positive_regulation of VTA1 13 0.59 3.81 8.13
39 INT48314 Gene_expression of NTRK2 17 0.75 7.84 7.83
40 INT74520 Positive_regulation of CD68 30 0.61 31.68 7.59
41 INT171146 Negative_regulation of Gene_expression of Fig4 38 0.37 11.41 7.42
42 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33
43 INT47691 Positive_regulation of Gene_expression of Ntrk2 17 0.62 13.64 6.96
44 INT195442 Gene_expression of FIG4 23 0.65 5.13 6.92
45 INT15092 Positive_regulation of SLC6A4 17 0.67 7.32 6.7
46 INT234813 Gene_expression of RAB5A 58 0.66 3.67 6.48
47 INT218698 Negative_regulation of Positive_regulation of Fig4 11 0.20 6.01 6.32
48 INT47681 Regulation of Ntrk2 17 0.62 3.61 6.31
49 INT11154 Binding of EGFR 149 0.48 96.23 6.29
50 INT57256 Gene_expression of HLA-DQA2 52 0.55 23.87 6.27
51 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21
52 INT88245 Gene_expression of Slc11a1 42 0.53 18.86 6.2
53 INT109714 Transcription of SLC6A4 7 0.72 3.8 6.19
54 INT49027 Gene_expression of TYRP1 35 0.75 9.81 6.06
55 INT251958 Gene_expression of VTA1 9 0.58 7.26 5.6
56 INT23401 Gene_expression of HLA-DOA 91 0.30 38.21 5.52
57 INT97145 Positive_regulation of TBK1 14 0.12 15.32 5.43
58 INT183467 Negative_regulation of TBK1 6 0.12 9.89 5.41
59 INT95759 Gene_expression of DIO3 5 0.51 2.55 5.28
60 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23
61 INT137593 Regulation of Gene_expression of SLC6A4 7 0.60 2.59 5.23
62 INT22597 Positive_regulation of TF 43 0.68 27.27 5.17
63 INT68591 Regulation of TYRP1 14 0.44 3.93 5.05
64 INT216754 Binding of ATP6V0A1 5 0.11 0.71 4.98
65 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93
66 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
67 INT255981 Localization of RAB5A 3 0.68 0.88 4.76
68 INT269476 Binding of RAB5A 1 0.41 0 4.76
69 INT21855 Gene_expression of Ap3d1 4 0.32 12.21 4.66
70 INT173273 Positive_regulation of Phosphorylation of Fig4 16 0.30 7.3 4.62
71 INT65056 Binding of Ntrk2 20 0.36 3.72 4.42
72 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33
73 INT148901 Binding of Sort1 2 0.39 3.65 4.32
74 INT47686 Regulation of Gene_expression of Ntrk2 5 0.44 5.24 4.14
75 INT144428 Positive_regulation of Gene_expression of Erbb2 41 0.69 41.4 4.13
76 INT83035 Binding of INSR 16 0.47 9.29 4.11
77 INT72385 Phosphorylation of Shc1 11 0.52 1.62 4.1
78 INT79343 Positive_regulation of Slc6a4 10 0.50 1.77 4.05
79 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99
80 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
81 INT140670 Negative_regulation of Gene_expression of SLC6A4 4 0.51 2.7 3.88
82 INT209018 Positive_regulation of Slc11a1 11 0.55 7.12 3.83
83 INT18822 Regulation of Cubn 4 0.27 0.17 3.74
84 INT123908 Positive_regulation of HLA-DQB1 12 0.21 10.5 3.71
85 INT142501 Transcription of Tyrp1 4 0.18 2.09 3.71
86 INT173751 Transcription of Fig4 31 0.46 8.28 3.7
87 INT134527 Phosphorylation of Ntrk2 7 0.69 3.72 3.65
88 INT32905 Gene_expression of Mrc1 18 0.58 11.07 3.54
89 INT242569 Positive_regulation of Ret 17 0.55 3.61 3.54
90 INT10116 Localization of INSR 11 0.57 5.43 3.48
91 INT57728 Regulation of LDLR 25 0.41 13.18 3.46
92 INT148899 Regulation of Sort1 2 0.50 2.72 3.46
93 INT163832 Negative_regulation of Gene_expression of EGFR 50 0.59 39.71 3.45
94 INT18073 Positive_regulation of TYRP1 11 0.67 1.98 3.36
95 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32
96 INT99291 Transcription of Slc6a4 7 0.46 1.16 3.28
97 INT127455 Positive_regulation of Gene_expression of Slc6a4 9 0.59 5.62 3.2
98 INT54369 Regulation of VTA1 4 0.38 3.03 3.18
99 INT187505 Positive_regulation of Localization of Fig4 16 0.24 1.21 3.17
100 INT100190 Regulation of Gene_expression of Slc6a4 5 0.39 1.8 3.14
101 INT16729 Positive_regulation of LOC308670 10 0.65 1.63 3.11
102 INT117348 Regulation of EGFR 75 0.61 47.73 3.09
103 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04
104 INT92335 Gene_expression of TBK1 11 0.28 8.98 3
105 INT21853 Regulation of Ap3d1 3 0.10 1.4 2.95
106 INT57699 Positive_regulation of CD1A 11 0.50 8.49 2.93
107 INT52878 Positive_regulation of ATP6V0A1 9 0.54 1.35 2.92
108 INT72384 Positive_regulation of Phosphorylation of Shc1 1 0.32 0.48 2.9
109 INT271447 Positive_regulation of Positive_regulation of HLA-DQB1 1 0.06 5.87 2.8
110 INT54370 Negative_regulation of VTA1 5 0.50 2.06 2.77
111 INT204524 Binding of TLR9 17 0.43 11.69 2.76
112 INT91319 Positive_regulation of CD63 6 0.63 3.86 2.76
113 INT97132 Negative_regulation of Positive_regulation of TBK1 5 0.08 6.54 2.76
114 INT24712 Positive_regulation of Ap3d1 18 0.54 8.58 2.71
115 INT234825 Positive_regulation of Gene_expression of RAB5A 16 0.59 1.15 2.71
116 INT187499 Positive_regulation of Positive_regulation of Fig4 9 0.21 3.28 2.69
117 INT100360 Negative_regulation of TF 19 0.42 10.43 2.68
118 INT209889 Gene_expression of TRAF6 13 0.63 6.85 2.67
119 INT83073 Negative_regulation of Tyrp1 10 0.23 4.4 2.65
120 INT83642 Gene_expression of CD63 22 0.77 10.06 2.63
121 INT176531 Gene_expression of SHC1 3 0.67 9.5 2.62
122 INT80320 Negative_regulation of Gene_expression of Slc6a4 4 0.42 0.85 2.6
123 INT132685 Negative_regulation of NTRK2 4 0.42 2.89 2.58
124 INT18969 Gene_expression of HLA-DQA1 29 0.65 12.19 2.54
125 INT30040 Negative_regulation of TYRP1 11 0.51 2.72 2.54
126 INT136681 Gene_expression of Shc1 13 0.77 9.67 2.52
127 INT38631 Positive_regulation of Ret 8 0.39 3.23 2.52
128 INT67621 Negative_regulation of Gene_expression of Ntrk2 7 0.41 2.71 2.52
129 INT95799 Binding of NTRK2 8 0.35 2.95 2.47
130 INT74064 Gene_expression of SPG21 9 0.75 4.14 2.45
131 INT174876 Regulation of Gene_expression of Fig4 18 0.39 7.83 2.44
132 INT37341 Regulation of Tyrp1 4 0.29 4.53 2.42
133 INT63333 Gene_expression of RET 24 0.76 30.09 2.41
134 INT183468 Localization of TBK1 6 0.32 4.35 2.36
135 INT209019 Localization of Slc11a1 12 0.33 4.33 2.33
136 INT242548 Regulation of Gene_expression of Ret 7 0.49 1.2 2.33
137 INT190028 Positive_regulation of Mrc1 10 0.22 2.94 2.26
138 INT47687 Positive_regulation of Transcription of Ntrk2 5 0.45 2.42 2.24
139 INT50392 Regulation of Ret 6 0.54 3.51 2.22
140 INT219180 Gene_expression of TLR7 13 0.68 9.51 2.21
141 INT242551 Negative_regulation of Gene_expression of Ret 5 0.41 1.01 2.21
142 INT100622 Localization of CD68 16 0.73 6.58 2.2
143 INT152554 Regulation of Transcription of SLC6A4 3 0.62 1.52 2.18
144 INT209027 Positive_regulation of Positive_regulation of Slc11a1 3 0.14 2.41 2.18
145 INT195191 Gene_expression of Cubn 2 0.06 0 2.17
146 INT66881 Positive_regulation of Sort1 2 0.57 0.99 2.16
147 INT96841 Regulation of Slc11a1 9 0.36 6.83 2.14
148 INT94628 Gene_expression of CD1D 12 0.75 5.58 2.13
149 INT83896 Gene_expression of CD1A 19 0.68 15.58 2.1
150 INT304987 Positive_regulation of Localization of VTA1 1 0.31 0.64 2.1
151 INT156720 Localization of CD1D 7 0.68 1.1 2.09
152 INT102896 Binding of Ret 8 0.35 1.55 2.03
153 INT107987 Gene_expression of MRC1 27 0.75 36.94 1.99
154 INT195430 Regulation of Positive_regulation of SLC6A4 1 0.42 1.01 1.98
155 INT66882 Gene_expression of Sort1 3 0.73 0.64 1.97
156 INT16710 Negative_regulation of Slc30a2 4 0.24 0 1.96
157 INT216848 Gene_expression of TCIRG1 8 0.52 2.59 1.95
158 INT122534 Binding of Shc1 6 0.48 3.59 1.94
159 INT155015 Positive_regulation of HLA-DOA 6 0.23 4.45 1.92
160 INT207777 Binding of Ap3d1 1 0.07 14.51 1.91
161 INT41633 Positive_regulation of Positive_regulation of Cubn 2 0.48 0.1 1.89
162 INT65545 Localization of EGFR 35 0.79 20.8 1.88
163 INT257755 Positive_regulation of SHC1 1 0.60 4.97 1.87
164 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
165 INT240058 Gene_expression of RHOB 2 0.55 4.29 1.84
166 INT96746 Gene_expression of Lamp1 2 0.03 1.82 1.81
167 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8
168 INT141937 Negative_regulation of Regulation of SLC6A4 1 0.41 0.27 1.8
169 INT84548 Positive_regulation of HLA-DQA1 5 0.49 1.68 1.75
170 INT218303 Protein_catabolism of INSR 3 0.29 0.67 1.73
171 INT232645 Transcription of INSR 2 0.09 1.19 1.71
172 INT234827 Positive_regulation of RAB5A 3 0.59 0.54 1.69
173 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68
174 INT96842 Binding of Slc11a1 16 0.34 7.15 1.66
175 INT50740 Positive_regulation of SPG21 18 0.67 8.3 1.65
176 INT30037 Binding of TYRP1 9 0.36 0.45 1.6
177 INT240059 Binding of RHOB 7 0.48 3.96 1.59
178 INT136680 Negative_regulation of Gene_expression of Shc1 4 0.43 3.36 1.57
179 INT147808 Positive_regulation of Gene_expression of SLC6A4 4 0.50 1.03 1.57
180 INT9466 Binding of APOB 27 0.41 19.36 1.56
181 INT242572 Positive_regulation of Gene_expression of Ret 6 0.40 0.29 1.56
182 INT118292 Negative_regulation of Phosphorylation of EGFR 27 0.59 13.62 1.54
183 INT21852 Regulation of Gene_expression of Ap3d1 2 0.18 1.34 1.54
184 INT304985 Negative_regulation of Localization of VTA1 1 0.28 0.7 1.52
185 INT150156 Positive_regulation of Gene_expression of HLA-DOA 7 0.20 4.07 1.5
186 INT186022 Negative_regulation of Transcription of Fig4 6 0.28 2.09 1.5
187 INT52962 Binding of ERBB2 77 0.47 50.03 1.49
188 INT167085 Negative_regulation of ERBB2 67 0.57 44.6 1.48
189 INT204530 Positive_regulation of Gene_expression of TLR9 14 0.70 6.85 1.48
190 INT189302 Positive_regulation of Gene_expression of HLA-DQA2 6 0.06 4.44 1.48
191 INT145177 Positive_regulation of Gene_expression of Tyrp1 5 0.30 3.31 1.46
192 INT258048 Regulation of TBK1 4 0.05 3.81 1.44
193 INT54593 Positive_regulation of Gene_expression of TF 16 0.68 9.05 1.43
194 INT136678 Positive_regulation of Gene_expression of Shc1 4 0.50 2.93 1.42
195 INT62425 Regulation of Gene_expression of Tyrp1 7 0.29 1.44 1.41
196 INT65153 Binding of HLA-DPB1 5 0.34 3.29 1.4
197 INT323338 Positive_regulation of Positive_regulation of Tyrp1 2 0.13 1.53 1.4
198 INT271448 Regulation of HLA-DQB1 1 0.06 2.73 1.4
199 INT64952 Binding of HLA-DQA2 11 0.10 7.23 1.39
200 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39
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