GO:0010038

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Name response to metal ion
Categary Process
Go Slim No
Go Link GO:0010038
Unique Molecular Interactions 180
Total Molecular Interactions 236
Total Single Events 3920
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to metal ion. They are ordered first by their pain relevance and then by number of times they were reported for response to metal ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
2 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
3 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
4 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
5 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
6 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
7 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
8 INT63939 Vta1 Positive_regulation of Th 1 0.14 0 1.61
9 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
10 INT40887 Penk Regulation of Th 1 0.04 0 1.53
11 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
12 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
13 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
14 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
15 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
16 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
17 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
18 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
19 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
20 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
21 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
22 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
23 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
24 INT106069 TH Positive_regulation of Th 1 0.07 0.16 1.14
25 INT88446 Uncx Positive_regulation of Th 1 0.13 0 1.1
26 INT31547 Binding of Th and Vip 1 0.31 0 1.08
27 INT81583 Cyp3a23/3a1 Positive_regulation of st 1 0.04 0 1.08
28 INT81580 Cyp3a23/3a1 Positive_regulation of Nudt14 1 0.01 0 1.08
29 INT41175 Adra2a Regulation of Th 1 0.59 0 1.04
30 INT31548 Binding of Th and Dbh 1 0.35 0 0.98
31 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
32 INT130282 Cyp3a23/3a1 Positive_regulation of Gene_expression of Npy 1 0.15 0 0.94
33 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
34 INT279166 Binding of Cyp3a23/3a1 and Nr3c2 1 0.00 0.61 0.9
35 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
36 INT253995 Binding of Cxcl12 and Cyp3a23/3a1 1 0.06 1.28 0.85
37 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
38 INT65807 Nr3c1 Positive_regulation of Cyp3a23/3a1 1 0.14 0 0.82
39 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
40 INT63940 Negative_regulation of Vta1 Positive_regulation of Th 1 0.13 0 0.81
41 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8
42 INT130283 Cyp3a23/3a1 Positive_regulation of Transcription of Npy 1 0.10 0 0.79
43 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
44 INT218933 Cyp3a23/3a1 Regulation of Alpi 1 0.00 1.07 0.73
45 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
46 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
47 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65
48 INT113685 Binding of Cyp3a23/3a1 and Cyp2c11 1 0.35 0 0.65
49 INT351445 Binding of Vta1 and Positive_regulation of Casp3 1 0.01 0.39 0.64
50 INT7958 LOC686180 Positive_regulation of Gene_expression of Th 1 0.02 0 0.64
51 INT106754 Pes1 Positive_regulation of Casp3 1 0.13 0 0.63
52 INT106752 Negative_regulation of Pes1 Positive_regulation of Casp3 1 0.12 0 0.63
53 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 0.11 0 0.61
54 INT52816 Cyp3a23/3a1 Regulation of Localization of LH 1 0.03 0.16 0.6
55 INT133320 Penk Negative_regulation of Gene_expression of Casp3 1 0.11 0.91 0.6
56 INT43692 Cyp3a23/3a1 Negative_regulation of Gh1 1 0.04 0 0.59
57 INT43693 Cyp3a23/3a1 Positive_regulation of Localization of Prl 1 0.10 0 0.57
58 INT147040 Hmbs Negative_regulation of Nppa 1 0.07 0.95 0.55
59 INT253998 Cyp3a23/3a1 Positive_regulation of Binding of Cxcl12 1 0.10 0.65 0.55
60 INT253990 Cyp3a23/3a1 Positive_regulation of Cxcl12 1 0.09 0.65 0.55
61 INT112399 Olr897-ps Regulation of Gene_expression of Casp3 1 0.03 0 0.54
62 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
63 INT74517 Binding of Casp3 and Cnrip1 1 0.31 0 0.51
64 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
65 INT7957 Calca Positive_regulation of Gene_expression of Th 1 0.39 0 0.47
66 INT281982 Cyp3a23/3a1 Negative_regulation of Gene_expression of MDK 1 0.00 0.67 0.47
67 INT218932 Cyp3a23/3a1 Regulation of Gene_expression of Alpi 1 0.00 0.53 0.46
68 INT121837 Sct Positive_regulation of Th 1 0.23 0.06 0.43
69 INT139487 Oprm1 Positive_regulation of Th 1 0.26 0.1 0.42
70 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
71 INT57236 Casp3 Positive_regulation of Prl 1 0.09 0 0.41
72 INT57235 Casp3 Positive_regulation of Localization of Prl 1 0.15 0 0.4
73 INT7625 Man2a2 Regulation of Th 1 0.01 0.07 0.4
74 INT275402 Trpv1 Regulation of Gene_expression of NDRG1 1 0.00 1.25 0.39
75 INT31794 Hps6 Positive_regulation of Th 1 0.03 0 0.38
76 INT52960 Casp3 Negative_regulation of Positive_regulation of Ltp 1 0.02 0 0.37
77 INT173476 Th Regulation of Gene_expression of Bcar1 1 0.10 0 0.34
78 INT34855 Negative_regulation of Maoa Negative_regulation of Th 1 0.17 0 0.34
79 INT181451 Lck Regulation of Mbp 1 0.08 1.43 0.34
80 INT173478 Th Regulation of Localization of Ins1 1 0.13 0 0.34
81 INT153019 nct Positive_regulation of Transcription of Th 1 0.19 0.61 0.32
82 INT153020 nct Positive_regulation of Gene_expression of Th 1 0.19 0.61 0.32
83 INT78064 Cyp3a23/3a1 Regulation of Localization of Il6 1 0.08 0.07 0.32
84 INT147041 Hmbs Negative_regulation of Negative_regulation of Nppa 1 0.05 0.51 0.3
85 INT55404 Binding of ENG and Th 1 0.02 0 0.3
86 INT281970 Cyp3a23/3a1 Negative_regulation of Gene_expression of Tie1 1 0.00 0.46 0.3
87 INT218934 Cyp3a23/3a1 Negative_regulation of Ephb1 1 0.01 0.95 0.28
88 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
89 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
90 INT78065 Cyp3a23/3a1 Negative_regulation of Gene_expression of Il6 1 0.12 0.07 0.27
91 INT218931 Cyp3a23/3a1 Regulation of Gene_expression of Akp3 1 0.00 0.55 0.27
92 INT78061 Cyp3a23/3a1 Negative_regulation of Localization of Il6 1 0.12 0.07 0.27
93 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
94 INT57172 Binding of RYBP and Cyp2b1 1 0.02 0 0.23
95 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22
96 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22
97 INT349344 Bdnf Negative_regulation of Casp3 1 0.13 0.96 0.22
98 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22
99 INT181675 Positive_regulation of Casp9 Positive_regulation of Casp3 1 0.06 0.51 0.2
100 INT315384 Adcyap1 Negative_regulation of Positive_regulation of Casp3 1 0.02 0.53 0.2
101 INT61987 Th Regulation of Penk 1 0.46 0 0.2
102 INT181677 Casp9 Positive_regulation of Casp3 1 0.06 0.5 0.19
103 INT261387 Nsdhl Negative_regulation of Casp3 1 0.03 1.08 0.19
104 INT351442 Gria2 Regulation of Gene_expression of Casp3 1 0.01 0 0.18
105 INT275400 Casp3 Positive_regulation of NDRG1 1 0.00 1.36 0.18
106 INT88450 Uncx Regulation of Gene_expression of Th 1 0.06 0 0.17
107 INT96416 CYC1 Positive_regulation of Casp3 1 0.02 0.96 0.17
108 INT247656 Binding of Tnnc1 and Gdf15 1 0.02 0.94 0.16
109 INT176623 Binding of PTGER2 and NDRG1 1 0.00 0.1 0.16
110 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
111 INT275374 JUN Positive_regulation of NDRG1 1 0.00 1.35 0.15
112 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15
113 INT275375 Binding of ITIH4 and NDRG1 1 0.00 0.65 0.14
114 INT275396 Binding of NDRG1 and Htatsf1 1 0.00 0.65 0.14
115 INT226205 Negative_regulation of Akt1 Positive_regulation of Casp3 1 0.04 0.71 0.14
116 INT304824 Binding of Rasa1 and Tnnc1 1 0.01 0 0.13
117 INT261456 Sftpd Positive_regulation of Gene_expression of Th 1 0.10 0.77 0.13
118 INT57170 Binding of Cyp1a1 and Cyp2b1 1 0.39 0 0.13
119 INT254002 Binding of Cyp3a23/3a1 and Positive_regulation of Gene_expression of Mif 1 0.08 0.56 0.13
120 INT275397 Binding of ITIH4 and Casp3 1 0.02 0.64 0.13
121 INT252631 Binding of Casp3 and Tnfrsf1a 1 0.10 0.69 0.13
122 INT275389 Binding of Casp3 and Htatsf1 1 0.00 0.64 0.13
123 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
124 INT252632 Binding of Casp3 and Tradd 1 0.11 0.68 0.12
125 INT349345 Bdnf Negative_regulation of Positive_regulation of Casp3 1 0.13 1.02 0.12
126 INT315391 IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
127 INT315390 Positive_regulation of IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
128 INT142961 Binding of Nfkb1 and Casp3 1 0.00 1.02 0.11
129 INT285023 Casp3 Negative_regulation of Casp7 1 0.07 0.44 0.1
130 INT261262 AIS Negative_regulation of Cyp19a1 1 0.01 0.2 0.08
131 INT80930 Tnf Positive_regulation of Negative_regulation of Cyp2b1 1 0.10 0.21 0.08
132 INT213933 AR Negative_regulation of Cyp19a1 1 0.07 0.79 0.07
133 INT19725 Cyp2b1 Positive_regulation of Cyp2c22 1 0.02 0 0.07
134 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
135 INT337692 Cyp2b2 Positive_regulation of Nr1i3 1 0.00 0.31 0.05
136 INT235313 Cyp3a23/3a1 Positive_regulation of Ins1 1 0.14 0.82 0.05
137 INT247847 Narfl Positive_regulation of Positive_regulation of Casp3 1 0.02 0.79 0
138 INT176564 Binding of Cyp17a1 and Cyp19a1 1 0.03 0.33 0
139 INT315395 Regulation of Binding of IFNA1 and Tp53 1 0.00 0.46 0
140 INT292968 Fto Regulation of Gene_expression of Th 1 0.30 1.11 0
141 INT125656 Cyp2e1 Positive_regulation of Transcription of Cyp2b2 1 0.07 0 0
142 INT338838 Binding of Cat and Tnnc1 1 0.03 1.77 0
143 INT292970 Fto Regulation of Th 1 0.18 0.48 0
144 INT315397 Binding of IFNA1 and Tp53 1 0.00 0.43 0
145 INT286044 Wwox Positive_regulation of Tp53 1 0.05 0.63 0
146 INT125648 Cyp2c11 Positive_regulation of Transcription of Cyp3a23/3a1 1 0.42 0 0
147 INT125646 Cyp2b2 Positive_regulation of Transcription of Cyp2e1 1 0.07 0 0
148 INT127058 Vta1 Negative_regulation of Positive_regulation of Th 1 0.33 0 0
149 INT125642 Cyp2b2 Positive_regulation of Transcription of Cyp2c6 1 0.06 0 0
150 INT315069 ITGB4 Regulation of MT1X 1 0.27 0.52 0
151 INT337708 Naf1 Regulation of Gene_expression of Tp53 1 0.09 0.22 0
152 INT125655 Cyp2c6 Positive_regulation of Transcription of Cyp2b2 1 0.06 0 0
153 INT125647 Cyp2c11 Positive_regulation of Transcription of Cyp2b2 1 0.07 0 0
154 INT177790 MTF1 Positive_regulation of NR2F1 1 0.10 0 0
155 INT315049 IGF1R Regulation of MT1X 1 0.29 0.52 0
156 INT49943 Binding of Th and Pdx1 1 0.02 0.17 0
157 INT338839 Negative_regulation of Binding of Cat and Tnnc1 1 0.04 1.78 0
158 INT177788 NR4A1 Positive_regulation of MTF1 1 0.08 0 0
159 INT325375 Binding of Tp53 and Positive_regulation of Positive_regulation of PARP1 1 0.05 0.59 0
160 INT177785 Negative_regulation of MTF1 Negative_regulation of MT1F 1 0.03 0.16 0
161 INT125659 Cyp2b2 Positive_regulation of Transcription of Cyp3a23/3a1 1 0.06 0 0
162 INT351977 Binding of Tp53 and Trib3 1 0.01 0.79 0
163 INT229809 Fos Regulation of Casp3 1 0.06 0.32 0
164 INT163744 Binding of Th and Gfra4 1 0.09 0 0
165 INT176569 Binding of FSHR and Cyp19a1 1 0.04 0.06 0
166 INT300307 Binding of Tp53 and Sirt1 1 0.24 0.98 0
167 INT351976 Binding of Tp53 and Stk11 1 0.13 2.3 0
168 INT286029 Binding of Tp53 and Atf2 1 0.03 0.33 0
169 INT294428 PSEN2 Regulation of Gene_expression of Tp53 1 0.49 0.86 0
170 INT125657 Cyp2b2 Positive_regulation of Transcription of Cyp2c11 1 0.07 0 0
171 INT177789 MTF1 Positive_regulation of NR4A1 1 0.08 0 0
172 INT194264 Tnnc1 Regulation of Mb 1 0.00 0.16 0
173 INT125654 Cyp2e1 Positive_regulation of Transcription of Cyp3a23/3a1 1 0.43 0 0
174 INT294429 PSEN2 Negative_regulation of Tp53 1 0.46 1.03 0
175 INT125649 Cyp2c6 Positive_regulation of Transcription of Cyp3a23/3a1 1 0.40 0 0
176 INT242159 Wnt2 Positive_regulation of Localization of Casp3 1 0.05 0.25 0
177 INT277622 Esr1 Positive_regulation of Gene_expression of Cyp19a1 1 0.03 1.37 0
178 INT265547 Positive_regulation of Tp53 Positive_regulation of Gene_expression of Kras 1 0.01 0.93 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to metal ion. They are ordered first by their pain relevance and then by number of times they were reported in response to metal ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
2 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
3 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
4 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
5 INT7327 Regulation of Th 164 0.62 29.67 110.14
6 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
7 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
8 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
9 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
10 INT350 Localization of Th 79 0.80 10.26 41.17
11 INT7326 Transcription of Th 83 0.72 13.5 35.33
12 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89
13 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31
14 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
15 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
16 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
17 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78
18 INT13643 Phosphorylation of Th 20 0.82 1.9 20.97
19 INT8765 Positive_regulation of Cyp3a23/3a1 63 0.67 22.28 20.39
20 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
21 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
22 INT32706 Gene_expression of Cyp3a23/3a1 51 0.65 19.48 15.06
23 INT18191 Negative_regulation of Cyp3a23/3a1 48 0.57 10.21 13.38
24 INT28014 Localization of Cyp3a23/3a1 34 0.77 9.8 12.96
25 INT31368 Positive_regulation of Positive_regulation of Th 19 0.51 2.2 12.68
26 INT141 Binding of Th 21 0.48 3.53 11.04
27 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
28 INT48496 Regulation of Transcription of Th 16 0.54 2.29 10.02
29 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
30 INT10597 Gene_expression of Cyp19a1 27 0.78 7.48 9.11
31 INT77490 Positive_regulation of Tnnc1 85 0.68 43.54 9.07
32 INT98178 Localization of Casp3 32 0.65 21.01 7.77
33 INT26643 Negative_regulation of Positive_regulation of Th 12 0.59 1.26 7.74
34 INT7624 Positive_regulation of Regulation of Th 7 0.50 2.41 7
35 INT57232 Binding of Casp3 22 0.36 9.42 6.2
36 INT7569 Positive_regulation of Transcription of Th 19 0.70 2.6 6.17
37 INT135760 Regulation of Gene_expression of Cyp19a1 2 0.62 1.15 5.81
38 INT28015 Regulation of Cyp3a23/3a1 19 0.40 6.32 5.79
39 INT7623 Regulation of Regulation of Th 11 0.44 1.31 5.16
40 INT106667 Gene_expression of NDRG1 18 0.70 9.96 5.14
41 INT61245 Positive_regulation of Cyp2b2 9 0.64 0.41 4.7
42 INT40620 Regulation of Positive_regulation of Th 9 0.45 2.45 4.69
43 INT140199 Positive_regulation of Gene_expression of Cyp3a23/3a1 9 0.45 4.91 4.56
44 INT30165 Positive_regulation of Phosphorylation of Th 8 0.56 0.75 4.22
45 INT77823 Negative_regulation of Negative_regulation of Th 9 0.59 1.56 3.79
46 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56
47 INT8764 Positive_regulation of Positive_regulation of Cyp3a23/3a1 5 0.45 1.62 3.33
48 INT30166 Regulation of Phosphorylation of Th 4 0.50 0.52 3.33
49 INT69564 Binding of Cyp3a23/3a1 11 0.34 4.67 3.2
50 INT137656 Negative_regulation of Binding of Casp3 4 0.21 0.7 3.09
51 INT116376 Transcription of Cyp19a1 2 0.40 0.74 3.04
52 INT88852 Protein_catabolism of Casp3 28 0.65 23.57 2.74
53 INT4704 Positive_regulation of Negative_regulation of Th 4 0.50 0.06 2.56
54 INT13644 Negative_regulation of Phosphorylation of Th 2 0.43 0.06 2.51
55 INT106668 Positive_regulation of Gene_expression of NDRG1 3 0.10 1.93 2.49
56 INT131112 Phosphorylation of Casp3 7 0.63 4.1 2.46
57 INT15210 Negative_regulation of Transcription of Th 9 0.59 0.47 2.37
58 INT80391 Negative_regulation of Cyp2b2 4 0.54 0.12 2.36
59 INT15209 Negative_regulation of Regulation of Th 6 0.51 1.64 2.16
60 INT53392 Positive_regulation of Cyp2b1 8 0.68 0.68 2.13
61 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12
62 INT3784 Regulation of Hmbs 4 0.38 2.79 2.11
63 INT342803 Positive_regulation of Transcription of Cyp19a1 1 0.30 0.33 2.08
64 INT93789 Gene_expression of Tnnc1 28 0.76 17.3 1.99
65 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
66 INT81347 Regulation of Cyp19a1 7 0.40 2.1 1.94
67 INT113683 Positive_regulation of Negative_regulation of Cyp3a23/3a1 2 0.49 0.48 1.94
68 INT1834 Positive_regulation of Binding of Th 1 0.46 0 1.91
69 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
70 INT78044 Regulation of Tnnc1 9 0.52 12.3 1.76
71 INT154727 Regulation of Cyp2b2 2 0.25 0 1.76
72 INT22591 Negative_regulation of Hmbs 6 0.51 5.04 1.74
73 INT113684 Negative_regulation of Gene_expression of Cyp3a23/3a1 5 0.36 2.04 1.71
74 INT91043 Regulation of NDRG1 7 0.25 2.66 1.65
75 INT10596 Positive_regulation of Cyp19a1 10 0.42 2.08 1.62
76 INT12842 Binding of Cyp2b1 4 0.48 0 1.56
77 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
78 INT106749 Negative_regulation of Negative_regulation of Casp3 6 0.34 5.12 1.48
79 INT168682 Localization of NDRG1 3 0.36 0.84 1.45
80 INT140843 Regulation of Phosphorylation of Casp3 1 0.25 0.37 1.44
81 INT168684 Regulation of Localization of NDRG1 1 0.10 0.61 1.4
82 INT145221 Binding of Tp53 10 0.37 8.59 1.37
83 INT171690 Transcription of Casp3 8 0.55 2.62 1.36
84 INT97943 Positive_regulation of Protein_catabolism of Casp3 7 0.28 7.4 1.35
85 INT122345 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0 1.34
86 INT93702 Localization of Hmbs 1 0.81 4.84 1.26
87 INT57169 Gene_expression of Cyp2b1 5 0.72 1.39 1.2
88 INT26760 Negative_regulation of Localization of Th 2 0.40 0.09 1.14
89 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
90 INT89670 Negative_regulation of Binding of Th 2 0.43 0.28 1.12
91 INT131373 Positive_regulation of NDRG1 9 0.67 4.78 1.11
92 INT122347 Transcription of Hsd3b1 1 0.52 0 0.99
93 INT207325 Positive_regulation of Localization of Cyp3a23/3a1 1 0.42 0.61 0.98
94 INT61241 Gene_expression of Cyp2b2 1 0.56 0 0.92
95 INT75425 Binding of Tnnc1 7 0.35 5.39 0.91
96 INT22592 Positive_regulation of Hmbs 2 0.48 2.27 0.87
97 INT157981 Binding of Cyp2b2 1 0.44 0 0.86
98 INT157982 Positive_regulation of Gene_expression of Cyp2b2 1 0.43 0 0.85
99 INT131105 Positive_regulation of Negative_regulation of Casp3 3 0.29 3.15 0.84
100 INT53309 Regulation of Localization of Th 1 0.39 0 0.84
101 INT146942 Gene_expression of Lck 1 0.46 1.3 0.83
102 INT57135 Gene_expression of Hmbs 1 0.32 0.55 0.82
103 INT79344 Binding of Cyp19a1 4 0.33 0.61 0.8
104 INT181667 Regulation of Regulation of Casp3 1 0.22 1.7 0.77
105 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
106 INT129490 Negative_regulation of Protein_catabolism of Casp3 4 0.22 3.91 0.71
107 INT161339 Localization of Cyp19a1 1 0.73 1.32 0.71
108 INT93787 Negative_regulation of Tnnc1 6 0.26 5.81 0.67
109 INT351454 Regulation of Transcription of Casp3 1 0.02 0.51 0.67
110 INT207326 Regulation of Localization of Cyp3a23/3a1 1 0.43 0.74 0.65
111 INT22593 Negative_regulation of Positive_regulation of Hmbs 1 0.41 1.58 0.64
112 INT53396 Regulation of Gene_expression of Cyp3a23/3a1 7 0.38 3.04 0.63
113 INT34755 Negative_regulation of Cyp2b1 5 0.56 1.2 0.61
114 INT115823 Transcription of Cyp3a23/3a1 3 0.54 0.82 0.61
115 INT53391 Negative_regulation of Positive_regulation of Cyp2b1 2 0.41 0.24 0.61
116 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
117 INT154728 Regulation of Gene_expression of Cyp2b1 1 0.42 0 0.59
118 INT13929 Protein_catabolism of Th 3 1.00 0 0.58
119 INT157226 Positive_regulation of Gene_expression of Tnnc1 11 0.49 6.21 0.57
120 INT181673 Negative_regulation of Transcription of Casp3 3 0.34 0.61 0.55
121 INT353896 Negative_regulation of Phosphorylation of Cyp19a1 1 0.22 0.47 0.55
122 INT353893 Phosphorylation of Cyp19a1 1 0.31 0.46 0.55
123 INT139306 Positive_regulation of Transcription of Cyp3a23/3a1 1 0.45 0.31 0.52
124 INT203382 Regulation of MT1X 1 0.17 2.26 0.52
125 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
126 INT80929 Negative_regulation of Positive_regulation of Cyp3a23/3a1 3 0.43 0.83 0.48
127 INT122348 Regulation of Hsd3b1 1 0.60 0 0.46
128 INT129144 Regulation of Localization of Casp3 1 0.26 0.84 0.44
129 INT28016 Negative_regulation of Localization of Cyp3a23/3a1 2 0.04 0 0.43
130 INT84915 Negative_regulation of Gene_expression of Cyp19a1 2 0.15 1.29 0.42
131 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
132 INT164261 Binding of NDRG1 3 0.37 0.87 0.37
133 INT100759 Localization of Tnnc1 9 0.55 1.5 0.36
134 INT312831 Negative_regulation of Lck 3 0.13 2.46 0.36
135 INT181122 Positive_regulation of Gene_expression of Cyp19a1 1 0.02 0.68 0.36
136 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
137 INT181413 Regulation of Lck 2 0.36 2.54 0.33
138 INT246520 Positive_regulation of Positive_regulation of Tnnc1 1 0.49 2.54 0.33
139 INT93788 Regulation of Gene_expression of Tnnc1 2 0.44 1.34 0.29
140 INT94540 Gene_expression of MT1X 6 0.49 5.51 0.28
141 INT338834 Localization of Tnnc1 1 0.06 1.69 0.27
142 INT338835 Gene_expression of Tnnc1 1 0.05 1.69 0.27
143 INT40588 Regulation of Negative_regulation of Th 1 0.16 0.26 0.26
144 INT248664 Phosphorylation of Cyp3a23/3a1 2 0.14 0.94 0.24
145 INT141820 Positive_regulation of Binding of Casp3 1 0.12 0.55 0.24
146 INT270161 Positive_regulation of Phosphorylation of Lck 1 0.13 0.23 0.23
147 INT275394 Negative_regulation of NDRG1 1 0.01 0.91 0.21
148 INT195018 Regulation of Negative_regulation of Casp3 1 0.21 0.48 0.2
149 INT140716 Negative_regulation of Protein_catabolism of Th 1 0.59 0 0.19
150 INT140717 Positive_regulation of Protein_catabolism of Th 1 0.47 0 0.19
151 INT174246 Localization of Cyp2b1 2 0.68 1.58 0.17
152 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
153 INT216152 Binding of MTF1 2 0.23 0.41 0.15
154 INT94533 Positive_regulation of MT1X 1 0.44 1.78 0.14
155 INT177847 Positive_regulation of MTF1 2 0.29 0.48 0.13
156 INT168244 Regulation of Transcription of Tp53 1 0.33 0.57 0.13
157 INT70583 Negative_regulation of Binding of Cyp3a23/3a1 1 0.30 0.09 0.12
158 INT270159 Positive_regulation of Lck 1 0.09 0.12 0.11
159 INT270153 Phosphorylation of Lck 1 0.15 0.11 0.11
160 INT297456 Protein_catabolism of Tp53 1 0.11 0.72 0.1
161 INT111139 Localization of Tp53 4 0.45 2.4 0.09
162 INT115832 Negative_regulation of Transcription of Cyp3a23/3a1 1 0.34 0.51 0.09
163 INT115836 Regulation of Regulation of Cyp3a23/3a1 1 0.17 0.49 0.09
164 INT171688 Positive_regulation of Transcription of Casp3 3 0.28 1.16 0.08
165 INT247649 Negative_regulation of Gene_expression of Tnnc1 1 0.03 0.49 0.08
166 INT115830 Negative_regulation of Gene_expression of Cyp2b1 1 0.37 0.44 0.07
167 INT94525 Transcription of MT1X 1 0.43 1.08 0.07
168 INT177848 Gene_expression of MTF1 2 0.41 0.46 0.06
169 INT54293 Protein_catabolism of Cyp2b1 1 0.86 0 0.06
170 INT94541 Positive_regulation of Gene_expression of MT1X 1 0.44 1.84 0.06
171 INT270639 Binding of Lck 2 0.30 1.21 0.05
172 INT178927 Regulation of Gene_expression of Tp53 6 0.26 2.23 0
173 INT214913 Positive_regulation of Positive_regulation of Tp53 2 0.08 2.47 0
174 INT204059 Positive_regulation of Phosphorylation of Tp53 1 0.07 0.76 0
175 INT125634 Transcription of Cyp2b2 1 0.09 0 0
176 INT338836 Negative_regulation of Tnnc1 1 0.03 1.75 0
177 INT125632 Negative_regulation of Transcription of Cyp2b2 1 0.05 0 0
178 INT237443 Positive_regulation of Phosphorylation of Casp3 1 0.39 0.09 0
179 INT213932 Negative_regulation of Negative_regulation of Cyp19a1 1 0.31 0.7 0
180 INT177819 Negative_regulation of Gene_expression of MTF1 1 0.17 0.17 0
181 INT194353 Negative_regulation of Binding of Cyp19a1 1 0.15 0 0
182 INT177855 Negative_regulation of MTF1 1 0.23 0.16 0
183 INT167840 Negative_regulation of Localization of Tnnc1 1 0.19 0 0
184 INT253980 Positive_regulation of Binding of Cyp3a23/3a1 1 0.08 0 0
185 INT177873 Regulation of Gene_expression of MTF1 1 0.18 0.17 0
186 INT179957 Positive_regulation of Binding of Tp53 1 0.08 0.48 0
187 INT315117 Localization of MT1X 1 0.57 0.26 0
188 INT338837 Positive_regulation of Tnnc1 1 0.04 2.94 0
189 INT242155 Negative_regulation of Localization of Casp3 1 0.04 0.25 0
190 INT223765 Negative_regulation of Positive_regulation of Tp53 1 0.07 1.69 0
191 INT248670 Negative_regulation of Regulation of Cyp3a23/3a1 1 0.08 0.16 0
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