GO:0010040

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Name response to iron(II) ion
Categary Process
Go Slim No
Go Link GO:0010040
Unique Molecular Interactions 20
Total Molecular Interactions 26
Total Single Events 638
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to iron(II) ion. They are ordered first by their pain relevance and then by number of times they were reported for response to iron(II) ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
2 INT1311 Lct Positive_regulation of Localization of Gnrhr 1 0.03 0 0.45
3 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
4 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
5 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
6 INT129094 Binding of GRP and Pik3r1 1 0.00 0.49 0.12
7 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
8 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11
9 INT328413 Binding of Snca and Nlrp1a 1 0.06 0.75 0.1
10 INT281881 Binding of Aco1 and Ros1 1 0.01 1.93 0.1
11 INT83270 Snca Regulation of Napepld 1 0.14 0 0.09
12 INT239186 H2 Negative_regulation of Aco1 1 0.00 1.96 0.05
13 INT317313 Atp13a2 Negative_regulation of Snca 1 0.13 0.59 0
14 INT315541 ACO1 Negative_regulation of Gene_expression of ALAS2 1 0.17 0.18 0
15 INT49943 Binding of Th and Pdx1 1 0.02 0.17 0
16 INT315534 Binding of ACO1 and ERN1 1 0.01 0.18 0
17 INT252807 Binding of ACO1 and TFRC 1 0.01 1.83 0
18 INT317315 Gene_expression of Snca Negative_regulation of Psmb10 1 0.00 0.52 0
19 INT317320 Binding of Snca and Atp13a2 1 0.08 0.58 0
20 INT281880 Binding of Aco1 and Cish 1 0.00 0.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to iron(II) ion. They are ordered first by their pain relevance and then by number of times they were reported in response to iron(II) ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2336 Negative_regulation of Lct 51 0.58 33.79 13.73
2 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
3 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
4 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
5 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
6 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
7 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
8 INT32353 Regulation of Lct 7 0.52 1.37 3.16
9 INT123595 Regulation of Snca 7 0.62 4.3 3.06
10 INT120201 Gene_expression of Aco1 54 0.35 26.29 2.95
11 INT32983 Localization of Lct 8 0.47 0.42 2.6
12 INT110038 Negative_regulation of Aco1 26 0.23 17.41 2.2
13 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
14 INT281878 Positive_regulation of Gene_expression of Aco1 35 0.31 17.15 1.98
15 INT127125 Localization of Snca 6 0.81 8.24 1.88
16 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
17 INT28915 Binding of Lct 6 0.17 1.89 1.64
18 INT1462 Positive_regulation of Lct 7 0.49 1.5 1.61
19 INT201271 Phosphorylation of Snca 3 0.82 4.22 1.45
20 INT124247 Negative_regulation of Gene_expression of Snca 12 0.59 3.87 1.39
21 INT42530 Gene_expression of Lct 11 0.66 9.37 1.37
22 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19
23 INT151753 Transcription of Snca 6 0.69 1.99 1.11
24 INT202218 Positive_regulation of Aco1 4 0.27 12.31 1.06
25 INT292945 Positive_regulation of Positive_regulation of Snca 4 0.69 2.42 1.05
26 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03
27 INT151752 Positive_regulation of Transcription of Snca 2 0.50 0.99 0.92
28 INT124246 Binding of Snca 10 0.37 6.53 0.9
29 INT42479 Positive_regulation of Negative_regulation of Lct 2 0.50 1 0.89
30 INT46060 Regulation of Negative_regulation of Lct 1 0.27 0.96 0.45
31 INT148264 Transcription of SNCA 1 0.40 0.25 0.42
32 INT159561 Positive_regulation of Gene_expression of Lct 4 0.49 4.11 0.4
33 INT343972 Negative_regulation of Binding of SNCA 1 0.36 0.2 0.39
34 INT169628 Binding of SNCA 4 0.47 3.53 0.36
35 INT156399 Regulation of Pdx1 1 0.00 0.96 0.33
36 INT43217 Regulation of Localization of Lct 1 0.16 0.08 0.31
37 INT343973 Localization of SNCA 1 0.63 0.07 0.3
38 INT140422 Positive_regulation of Binding of Lct 1 0.23 0.07 0.28
39 INT49942 Positive_regulation of Pdx1 5 0.02 1.24 0.26
40 INT95758 Negative_regulation of ACO1 2 0.51 1.25 0.26
41 INT281874 Localization of Aco1 1 0.32 3.67 0.23
42 INT142052 Binding of Snca 4 0.47 1.02 0.22
43 INT281876 Regulation of Aco1 4 0.11 4 0.22
44 INT135644 Binding of Aco1 2 0.19 2.6 0.22
45 INT292944 Regulation of Positive_regulation of Snca 1 0.45 0.36 0.21
46 INT95760 Negative_regulation of Gene_expression of ACO1 1 0.00 0.93 0.2
47 INT257418 Negative_regulation of Transcription of Snca 1 0.43 0.93 0.19
48 INT166361 Phosphorylation of SNCA 1 0.70 0.72 0.17
49 INT157084 Localization of Snca 1 0.51 0.17 0.16
50 INT343974 Negative_regulation of Gene_expression of SNCA 1 0.31 0.09 0.16
51 INT319289 Protein_catabolism of Snca 1 0.35 0.93 0.15
52 INT286343 Negative_regulation of Gene_expression of Snca 1 0.26 0.65 0.15
53 INT42529 Protein_catabolism of Lct 1 0.28 0 0.13
54 INT281872 Positive_regulation of Positive_regulation of Aco1 1 0.20 1.3 0.12
55 INT129082 Positive_regulation of Pik3r1 1 0.00 0.47 0.11
56 INT131139 Binding of ACO1 3 0.27 1.81 0.1
57 INT95756 Gene_expression of ACO1 3 0.27 2.49 0.1
58 INT131140 Negative_regulation of Negative_regulation of ACO1 1 0.37 0.58 0.09
59 INT288642 Negative_regulation of Positive_regulation of Snca 1 0.07 0.93 0.09
60 INT123875 Localization of Pdx1 1 0.80 0.28 0.09
61 INT70606 Positive_regulation of Positive_regulation of Pdx1 1 0.02 0.4 0.09
62 INT292946 Positive_regulation of Localization of Snca 1 0.50 0.52 0.06
63 INT239158 Negative_regulation of Positive_regulation of Aco1 2 0.17 1.26 0.05
64 INT281875 Negative_regulation of Gene_expression of Aco1 1 0.17 0.48 0.05
65 INT281877 Regulation of Localization of Aco1 1 0.18 1.36 0.04
66 INT281871 Positive_regulation of Localization of Aco1 1 0.20 1.37 0.04
67 INT97829 Gene_expression of Pdx1 7 0.32 1.14 0
68 INT132735 Positive_regulation of Gene_expression of Pdx1 1 0.29 0 0
69 INT317275 Positive_regulation of Binding of Snca 1 0.37 0.53 0
70 INT49941 Negative_regulation of Pdx1 1 0.02 0.07 0
71 INT315623 Positive_regulation of Localization of ACO1 1 0.20 0.79 0
72 INT49938 Negative_regulation of Positive_regulation of Pdx1 1 0.02 0.07 0
73 INT315588 Regulation of ACO1 1 0.18 0.57 0
74 INT323587 Transcription of Aco1 1 0.03 0.1 0
75 INT49940 Positive_regulation of Negative_regulation of Pdx1 1 0.02 0.07 0
76 INT252749 Regulation of Gene_expression of ACO1 1 0.02 0.9 0
77 INT315574 Localization of ACO1 1 0.30 0.79 0
78 INT315616 Positive_regulation of Gene_expression of ACO1 1 0.20 0.79 0
79 INT315572 Positive_regulation of ACO1 1 0.20 0.94 0
80 INT323585 Regulation of Transcription of Aco1 1 0.02 0.1 0
81 INT343971 Positive_regulation of Positive_regulation of SNCA 1 0.42 0.35 0
82 INT260573 Transcription of Lct 1 0.26 0.49 0
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