GO:0010165

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Name response to X-ray
Categary Process
Go Slim No
Go Link GO:0010165
Unique Molecular Interactions 409
Total Molecular Interactions 511
Total Single Events 5019
Pain Genes Associated 26

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to X-ray. They are ordered first by their pain relevance and then by number of times they were reported for response to X-ray. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
3 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
4 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
5 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
6 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
7 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
8 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
9 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
10 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
11 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
12 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
13 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
14 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
15 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
16 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
17 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
18 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
19 INT166842 Binding of ANXA1 and Nfkb1 1 0.37 1.64 0.95
20 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
21 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
22 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
23 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
24 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
25 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
26 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
27 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
28 INT117412 RYBP Negative_regulation of LIG4 1 0.00 0.42 0.76
29 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
30 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
31 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65
32 INT351445 Binding of Vta1 and Positive_regulation of Casp3 1 0.01 0.39 0.64
33 INT106754 Pes1 Positive_regulation of Casp3 1 0.13 0 0.63
34 INT106752 Negative_regulation of Pes1 Positive_regulation of Casp3 1 0.12 0 0.63
35 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 0.11 0 0.61
36 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
37 INT133320 Penk Negative_regulation of Gene_expression of Casp3 1 0.11 0.91 0.6
38 INT195666 Binding of PROC and THBD 2 0.40 2.42 0.56
39 INT112399 Olr897-ps Regulation of Gene_expression of Casp3 1 0.03 0 0.54
40 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
41 INT60759 Ikbip Regulation of Gene_expression of Oprd1 1 0.01 0 0.52
42 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
43 INT74517 Binding of Casp3 and Cnrip1 1 0.31 0 0.51
44 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
45 INT228449 PMAIP1 Negative_regulation of Fgf2 1 0.00 0.07 0.49
46 INT228448 PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
47 INT228447 Negative_regulation of PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
48 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
49 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
50 INT57236 Casp3 Positive_regulation of Prl 1 0.09 0 0.41
51 INT57235 Casp3 Positive_regulation of Localization of Prl 1 0.15 0 0.4
52 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
53 INT52960 Casp3 Negative_regulation of Positive_regulation of Ltp 1 0.02 0 0.37
54 INT228446 PMAIP1 Regulation of Transcription of Mtpn 1 0.00 0 0.34
55 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
56 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
57 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
58 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
59 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
60 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
61 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
62 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
63 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
64 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
65 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
66 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
67 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
68 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
69 INT282649 Binding of THBD and PROCR 1 0.40 0.97 0.26
70 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
71 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
72 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
73 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
74 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
75 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
76 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
77 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
78 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
79 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
80 INT332481 ANXA1 Regulation of SGPP2 1 0.45 1.01 0.22
81 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22
82 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22
83 INT349344 Bdnf Negative_regulation of Casp3 1 0.13 0.96 0.22
84 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22
85 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
86 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
87 INT182606 Binding of MSH2 and MSH3 1 0.12 1.4 0.21
88 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
89 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
90 INT181675 Positive_regulation of Casp9 Positive_regulation of Casp3 1 0.06 0.51 0.2
91 INT315384 Adcyap1 Negative_regulation of Positive_regulation of Casp3 1 0.02 0.53 0.2
92 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
93 INT181677 Casp9 Positive_regulation of Casp3 1 0.06 0.5 0.19
94 INT261387 Nsdhl Negative_regulation of Casp3 1 0.03 1.08 0.19
95 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
96 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
97 INT253776 Binding of THBD and F2 1 0.00 1.15 0.18
98 INT351442 Gria2 Regulation of Gene_expression of Casp3 1 0.01 0 0.18
99 INT275400 Casp3 Positive_regulation of NDRG1 1 0.00 1.36 0.18
100 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
101 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
102 INT96416 CYC1 Positive_regulation of Casp3 1 0.02 0.96 0.17
103 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
104 INT301907 Binding of THBD and VWF 1 0.02 1.71 0.16
105 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
106 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
107 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
108 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15
109 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
110 INT29207 Msh2 Regulation of POMC 1 0.02 0.1 0.14
111 INT226205 Negative_regulation of Akt1 Positive_regulation of Casp3 1 0.04 0.71 0.14
112 INT178351 Binding of Il6 and Hp 1 0.00 0.61 0.14
113 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
114 INT332485 SGPP2 Regulation of ANXA1 1 0.27 0.69 0.13
115 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
116 INT275397 Binding of ITIH4 and Casp3 1 0.02 0.64 0.13
117 INT252631 Binding of Casp3 and Tnfrsf1a 1 0.10 0.69 0.13
118 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
119 INT275389 Binding of Casp3 and Htatsf1 1 0.00 0.64 0.13
120 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
121 INT252632 Binding of Casp3 and Tradd 1 0.11 0.68 0.12
122 INT349345 Bdnf Negative_regulation of Positive_regulation of Casp3 1 0.13 1.02 0.12
123 INT213144 TIMP1 Negative_regulation of THBD 1 0.04 1.16 0.12
124 INT213147 DAK Negative_regulation of THBD 1 0.00 1.16 0.12
125 INT315391 IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
126 INT253772 Binding of THBD and Hmgb1 1 0.05 0.95 0.12
127 INT253775 Negative_regulation of Binding of THBD and Hmgb1 1 0.06 0.69 0.12
128 INT315390 Positive_regulation of IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
129 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
130 INT142961 Binding of Nfkb1 and Casp3 1 0.00 1.02 0.11
131 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
132 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
133 INT285023 Casp3 Negative_regulation of Casp7 1 0.07 0.44 0.1
134 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
135 INT311738 Binding of Anxa1 and Plat 1 0.19 0.63 0.1
136 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
137 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
138 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
139 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09
140 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
141 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08
142 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08
143 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
144 INT195777 THBD Positive_regulation of PROC 1 0.00 1.26 0.08
145 INT253774 THBD Regulation of F2 1 0.00 0.61 0.08
146 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08
147 INT227836 Binding of ERCC6 and GPER 1 0.21 0.27 0.08
148 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
149 INT215693 Trib3 Regulation of Gene_expression of Ccnd1 1 0.00 0.09 0.07
150 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
151 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
152 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
153 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
154 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
155 INT140291 ROS1 Positive_regulation of TP53 1 0.52 1.27 0.06
156 INT190044 Binding of Msh2 and Msh6 2 0.32 0.77 0.05
157 INT265459 Phosphorylation of TP53 Positive_regulation of Localization of CASP9 1 0.17 1.16 0.05
158 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05
159 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05
160 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05
161 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
162 INT265454 Phosphorylation of TP53 Positive_regulation of CASP9 1 0.17 1.16 0.05
163 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05
164 INT193788 ITIH4 Regulation of Phosphorylation of TP53 1 0.07 0.45 0.05
165 INT332484 ANXA1 Positive_regulation of HSH2D 1 0.18 0.19 0.05
166 INT190050 Binding of Msh2 and Pms2 2 0.32 0.49 0.04
167 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04
168 INT206845 ANXA1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
169 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04
170 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04
171 INT329230 Negative_regulation of ATIC Positive_regulation of Trp53 1 0.00 0.58 0.04
172 INT207702 CCND1 Regulation of MSMB 1 0.22 0.69 0.04
173 INT323675 Binding of THBD and BDNF-AS 1 0.02 2.45 0.04
174 INT323674 Binding of TFPI and THBD 1 0.02 2.45 0.04
175 INT329228 ATIC Positive_regulation of Trp53 1 0.01 0.58 0.04
176 INT352619 Bcl2l12 Negative_regulation of Trp53 1 0.27 0.94 0.04
177 INT352613 Binding of Trp53 and Bcl2l12 1 0.23 0.94 0.04
178 INT170457 RASGRP1 Regulation of TP53 1 0.02 0.58 0.04
179 INT201726 Mapk8 Positive_regulation of Positive_regulation of Trp53 1 0.00 0.41 0.04
180 INT260267 Binding of TFAM and TP53 2 0.37 2.1 0.03
181 INT355036 CKAP4 Regulation of Positive_regulation of TP53 1 0.08 0.4 0.03
182 INT266903 Binding of Sod2 and Trp53 1 0.05 0 0.03
183 INT211873 TP53 Positive_regulation of Transcription of CD40 1 0.03 1.44 0.03
184 INT234625 TP53 Positive_regulation of IGFBP3 1 0.29 0.74 0.03
185 INT222532 Anxa1 Negative_regulation of Localization of Gh1 1 0.01 0.14 0.03
186 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
187 INT265464 CSPG4 Regulation of Gene_expression of TP53 1 0.09 0.23 0.03
188 INT338900 MYC Positive_regulation of Gene_expression of TP73 1 0.05 0.27 0.03
189 INT222538 Anxa1 Negative_regulation of Localization of Prl 1 0.04 0.14 0.03
190 INT277745 Trib3 Regulation of Ccnd1 1 0.00 0.41 0.03
191 INT314686 TP53 Regulation of Gene_expression of MDM2 1 0.21 0.96 0.03
192 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03
193 INT314677 TP53 Regulation of Positive_regulation of CDKN2A 1 0.27 0.97 0.03
194 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03
195 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03
196 INT223067 IFI27 Negative_regulation of CCND1 1 0.05 0.65 0.03
197 INT222475 Anxa1 Negative_regulation of Localization of LH 1 0.01 0.14 0.03
198 INT314690 TP53 Regulation of Gene_expression of ZBTB7A 1 0.33 0.97 0.03
199 INT211872 TP53 Positive_regulation of CD40 1 0.03 1.44 0.03
200 INT223066 CDKN1A Negative_regulation of CCND1 1 0.04 0.66 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to X-ray. They are ordered first by their pain relevance and then by number of times they were reported in response to X-ray. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
2 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
3 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
4 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
5 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
6 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
7 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
8 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
9 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
10 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
11 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
12 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
13 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
14 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64
15 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
16 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
17 INT4159 Gene_expression of Hp 33 0.72 12.49 8.39
18 INT3401 Positive_regulation of Hp 22 0.69 16.33 7.97
19 INT98178 Localization of Casp3 32 0.65 21.01 7.77
20 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
21 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
22 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
23 INT57232 Binding of Casp3 22 0.36 9.42 6.2
24 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93
25 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
26 INT60585 Regulation of TP53 59 0.59 54.55 5.21
27 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
28 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
29 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
30 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
31 INT85497 Gene_expression of Anxa1 6 0.77 4.7 3.68
32 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65
33 INT12844 Binding of TP63 15 0.47 10.57 3.38
34 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24
35 INT48042 Positive_regulation of Anxa1 5 0.50 3.64 3.19
36 INT137656 Negative_regulation of Binding of Casp3 4 0.21 0.7 3.09
37 INT134798 Gene_expression of ANXA1 15 0.75 13.94 2.99
38 INT21299 Negative_regulation of Hp 14 0.44 10.97 2.97
39 INT8103 Binding of TP53 46 0.44 40.2 2.96
40 INT15288 Regulation of Hp 11 0.60 3.68 2.89
41 INT88852 Protein_catabolism of Casp3 28 0.65 23.57 2.74
42 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66
43 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
44 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
45 INT131112 Phosphorylation of Casp3 7 0.63 4.1 2.46
46 INT80329 Positive_regulation of THBD 12 0.47 20.96 2.45
47 INT55952 Transcription of TP53 16 0.61 12.14 2.36
48 INT93396 Positive_regulation of Gene_expression of Ccnd1 13 0.52 8.59 2.26
49 INT117415 Negative_regulation of LIG4 4 0.04 1.59 2.17
50 INT166838 Positive_regulation of ANXA1 4 0.64 4.88 2.16
51 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12
52 INT93398 Negative_regulation of Gene_expression of Ccnd1 5 0.44 2.61 2.12
53 INT104402 Positive_regulation of CCND1 15 0.70 11.77 2.08
54 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
55 INT69702 Positive_regulation of PMAIP1 7 0.35 8.81 1.98
56 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
57 INT65855 Localization of TP53 18 0.76 17.08 1.89
58 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
59 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7
60 INT85498 Positive_regulation of Gene_expression of Anxa1 3 0.50 2.12 1.7
61 INT113985 Positive_regulation of TP63 9 0.50 8.79 1.62
62 INT107992 Gene_expression of MSH2 39 0.78 37.09 1.6
63 INT193823 Positive_regulation of Gene_expression of TP63 7 0.18 7.74 1.57
64 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
65 INT48398 Positive_regulation of Thbd 9 0.68 2.58 1.52
66 INT85499 Regulation of Anxa1 1 0.27 1.88 1.52
67 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
68 INT106749 Negative_regulation of Negative_regulation of Casp3 6 0.34 5.12 1.48
69 INT140843 Regulation of Phosphorylation of Casp3 1 0.25 0.37 1.44
70 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
71 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
72 INT172953 Binding of Trp53 33 0.37 20.76 1.41
73 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
74 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
75 INT145221 Binding of Tp53 10 0.37 8.59 1.37
76 INT121307 Gene_expression of Ercc1 4 0.73 12.69 1.37
77 INT171690 Transcription of Casp3 8 0.55 2.62 1.36
78 INT97943 Positive_regulation of Protein_catabolism of Casp3 7 0.28 7.4 1.35
79 INT155992 Gene_expression of THBD 16 0.66 17 1.24
80 INT174156 Localization of Trp53 16 0.72 13.52 1.18
81 INT191586 Localization of THBD 7 0.58 9.44 1.17
82 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
83 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
84 INT278117 Negative_regulation of TP63 5 0.32 3.38 1.13
85 INT71233 Negative_regulation of Anxa1 1 0.07 0.15 1.05
86 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
87 INT3402 Positive_regulation of Positive_regulation of Hp 2 0.49 1.05 1
88 INT122151 Localization of Anxa1 1 0.75 0.53 1
89 INT163280 Negative_regulation of Phosphorylation of CCND1 6 0.19 3.92 0.87
90 INT131105 Positive_regulation of Negative_regulation of Casp3 3 0.29 3.15 0.84
91 INT163289 Phosphorylation of CCND1 7 0.36 4.81 0.81
92 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
93 INT93559 Gene_expression of Thbd 13 0.75 6.58 0.8
94 INT147433 Gene_expression of BRCA2 7 0.62 7.02 0.79
95 INT181667 Regulation of Regulation of Casp3 1 0.22 1.7 0.77
96 INT44293 Regulation of TP63 6 0.24 2.88 0.76
97 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
98 INT198669 Binding of THBD 5 0.10 4.45 0.75
99 INT92142 Binding of MSH2 5 0.46 5.64 0.75
100 INT35804 Regulation of Gene_expression of Hp 3 0.34 0.68 0.75
101 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
102 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
103 INT129490 Negative_regulation of Protein_catabolism of Casp3 4 0.22 3.91 0.71
104 INT25663 Localization of PMAIP1 3 0.38 2.47 0.71
105 INT25176 Regulation of Msh2 3 0.37 0.48 0.68
106 INT351454 Regulation of Transcription of Casp3 1 0.02 0.51 0.67
107 INT25664 Negative_regulation of Localization of PMAIP1 1 0.09 0.09 0.66
108 INT130385 Gene_expression of ERCC6 7 0.77 8.36 0.63
109 INT189586 Regulation of THBD 5 0.17 5.15 0.61
110 INT164585 Regulation of PMAIP1 2 0.20 2.07 0.61
111 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
112 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
113 INT128498 Regulation of CCND1 17 0.39 12.51 0.58
114 INT333877 Protein_catabolism of LIG4 2 0.03 2.03 0.57
115 INT166836 Negative_regulation of Positive_regulation of ANXA1 2 0.39 1.15 0.57
116 INT122149 Binding of Anxa1 1 0.36 0.22 0.57
117 INT37750 Localization of ANXA1 2 0.74 1.72 0.56
118 INT181673 Negative_regulation of Transcription of Casp3 3 0.34 0.61 0.55
119 INT146802 Positive_regulation of Ccnd1 4 0.38 1.37 0.53
120 INT37749 Positive_regulation of Localization of ANXA1 1 0.01 0.67 0.53
121 INT154151 Positive_regulation of TP73 5 0.67 5.71 0.52
122 INT192946 Gene_expression of PMAIP1 2 0.27 1.77 0.52
123 INT25175 Gene_expression of Msh2 2 0.55 0.4 0.52
124 INT164584 Positive_regulation of Positive_regulation of PMAIP1 1 0.20 0.9 0.52
125 INT75498 Positive_regulation of Gene_expression of CCND1 21 0.68 19.4 0.51
126 INT146545 Negative_regulation of Gene_expression of MSH2 17 0.56 18.87 0.51
127 INT206876 Positive_regulation of Gene_expression of ANXA1 3 0.39 1.68 0.51
128 INT166837 Binding of ANXA1 2 0.34 0.85 0.51
129 INT258835 Localization of Ccnd1 3 0.53 2.7 0.5
130 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
131 INT124989 Positive_regulation of Gene_expression of Thbd 3 0.15 1.83 0.49
132 INT306741 Positive_regulation of Positive_regulation of TP63 2 0.05 1.16 0.49
133 INT146522 Negative_regulation of Positive_regulation of CCND1 3 0.30 2.04 0.48
134 INT278121 Negative_regulation of Negative_regulation of TP63 1 0.03 0 0.48
135 INT93400 Negative_regulation of Ccnd1 4 0.33 0.77 0.47
136 INT19212 Positive_regulation of Gene_expression of Hp 5 0.15 1.47 0.46
137 INT206858 Regulation of ANXA1 3 0.56 2.4 0.45
138 INT158643 Negative_regulation of Negative_regulation of CCND1 2 0.31 2.43 0.45
139 INT129144 Regulation of Localization of Casp3 1 0.26 0.84 0.44
140 INT122150 Positive_regulation of Localization of Anxa1 1 0.47 0.28 0.44
141 INT166839 Negative_regulation of ANXA1 1 0.37 0.88 0.43
142 INT121310 Positive_regulation of Ercc1 2 0.45 1.78 0.42
143 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
144 INT219001 Gene_expression of ERCC1 12 0.54 3.77 0.38
145 INT48397 Negative_regulation of Thbd 5 0.55 1.41 0.37
146 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
147 INT38598 Binding of Thbd 1 0.01 1.19 0.35
148 INT183920 Localization of Hp 1 0.29 0.93 0.33
149 INT45869 Negative_regulation of Gene_expression of Hp 1 0.42 0.65 0.31
150 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
151 INT183911 Negative_regulation of Phosphorylation of Hp 1 0.17 0.86 0.3
152 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
153 INT60757 Regulation of Ikbip 1 0.04 0 0.28
154 INT183919 Positive_regulation of Phosphorylation of Hp 1 0.20 0.8 0.28
155 INT183914 Phosphorylation of Hp 1 0.32 0.78 0.27
156 INT295320 Positive_regulation of Localization of THBD 1 0.26 1.31 0.27
157 INT186057 Binding of CCND1 8 0.31 5.92 0.26
158 INT166960 Positive_regulation of Negative_regulation of TP53 2 0.25 1.65 0.26
159 INT173223 Negative_regulation of BRCA2 7 0.54 6.79 0.25
160 INT314729 Regulation of Localization of TP53 1 0.30 2.5 0.25
161 INT113989 Regulation of Gene_expression of CCND1 11 0.44 7.57 0.24
162 INT154150 Regulation of TP73 3 0.15 2.81 0.24
163 INT141820 Positive_regulation of Binding of Casp3 1 0.12 0.55 0.24
164 INT189346 Positive_regulation of ERCC6 6 0.60 3.37 0.23
165 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
166 INT156886 Positive_regulation of Localization of TP53 1 0.48 0.87 0.23
167 INT121311 Positive_regulation of Gene_expression of Ercc1 3 0.62 1.23 0.21
168 INT152680 Negative_regulation of THBD 3 0.29 1.87 0.21
169 INT195018 Regulation of Negative_regulation of Casp3 1 0.21 0.48 0.2
170 INT154147 Gene_expression of TP73 7 0.34 3.97 0.19
171 INT146801 Regulation of Ccnd1 5 0.34 2.4 0.19
172 INT19359 Binding of BRCA2 5 0.47 2.63 0.19
173 INT89690 Binding of Brca2 2 0.37 1.8 0.18
174 INT182627 Regulation of MSH2 1 0.26 2.27 0.18
175 INT169875 Negative_regulation of Ercc1 3 0.43 3.07 0.17
176 INT227876 Transcription of ERCC6 1 0.68 1.87 0.17
177 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
178 INT337078 Negative_regulation of Localization of Trp53 1 0.20 1.3 0.17
179 INT189355 Phosphorylation of ERCC6 1 0.79 1.11 0.16
180 INT179086 Positive_regulation of Negative_regulation of Trp53 5 0.50 4.78 0.15
181 INT139201 Localization of TP63 4 0.32 2.56 0.15
182 INT145147 Negative_regulation of Gene_expression of TP63 4 0.42 2.91 0.15
183 INT125081 Positive_regulation of Binding of TP53 2 0.46 1.2 0.15
184 INT207805 Negative_regulation of Phosphorylation of Trp53 2 0.18 0.98 0.15
185 INT286749 Regulation of Localization of Trp53 1 0.06 1.39 0.15
186 INT182408 Localization of ERCC6 4 0.72 2.31 0.14
187 INT154148 Negative_regulation of Gene_expression of TP73 3 0.21 1.89 0.14
188 INT89691 Regulation of Brca2 1 0.23 0.56 0.13
189 INT168244 Regulation of Transcription of Tp53 1 0.33 0.57 0.13
190 INT182623 Localization of MSH2 3 0.77 5.49 0.12
191 INT181745 Positive_regulation of MSH2 4 0.48 5.73 0.11
192 INT146072 Binding of TP73 2 0.12 0.58 0.1
193 INT146902 Negative_regulation of Gene_expression of Thbd 2 0.06 1.04 0.1
194 INT345504 Binding of PMAIP1 1 0.15 1.7 0.1
195 INT297456 Protein_catabolism of Tp53 1 0.11 0.72 0.1
196 INT151702 Binding of ERCC6 6 0.37 1.47 0.09
197 INT111139 Localization of Tp53 4 0.45 2.4 0.09
198 INT215750 Transcription of Ccnd1 2 0.14 2.23 0.09
199 INT286183 Regulation of Blm 1 0.36 1.3 0.09
200 INT227880 Positive_regulation of Transcription of ERCC6 1 0.50 0.52 0.09
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