GO:0010226

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Name response to lithium ion
Categary Process
Go Slim No
Go Link GO:0010226
Unique Molecular Interactions 189
Total Molecular Interactions 227
Total Single Events 2364
Pain Genes Associated 21

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to lithium ion. They are ordered first by their pain relevance and then by number of times they were reported for response to lithium ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
2 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
3 INT34393 Oprd1 Negative_regulation of Adcy1 1 0.36 0 1.27
4 INT65203 OPRL1 Negative_regulation of ADCY1 1 0.19 0 1.19
5 INT49955 OPRM1 Positive_regulation of ADCY1 1 0.21 0.31 1.19
6 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18
7 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18
8 INT65204 PNOC Negative_regulation of ADCY1 1 0.07 0 1.14
9 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
10 INT53052 ANTXRL Negative_regulation of Negative_regulation of ADCY1 1 0.01 0.66 0.99
11 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94
12 INT199392 Pklr Positive_regulation of Prok2 1 0.34 1.3 0.91
13 INT52114 Oprd1 Regulation of ADCY1 2 0.05 0.46 0.9
14 INT64127 Igfbp2 Regulation of Localization of Avp 1 0.39 0.19 0.9
15 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
16 INT199391 Pklr Positive_regulation of Prokr1 1 0.31 1.28 0.87
17 INT52390 OPRD1 Regulation of ADCY1 1 0.09 0.13 0.86
18 INT270218 P2rx3 Positive_regulation of Pla2g4a 1 0.34 0.63 0.85
19 INT80877 Negative_regulation of PCDHB17 Negative_regulation of ADCY1 1 0.01 0.08 0.84
20 INT80878 PCDHB17 Negative_regulation of ADCY1 1 0.01 0.08 0.84
21 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
22 INT127545 Gria1 Positive_regulation of Gene_expression of Gnptab 1 0.00 0.7 0.83
23 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
24 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78
25 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
26 INT65593 CALCA Negative_regulation of Positive_regulation of ADCY1 1 0.23 0.07 0.76
27 INT311525 Binding of Gria1 and Ltp 1 0.00 0.1 0.73
28 INT190984 Binding of Scn2a1 and Gria1 1 0.03 0.08 0.71
29 INT51433 Gria1 Positive_regulation of Eif3g 1 0.03 0 0.7
30 INT199390 Pklr Regulation of Positive_regulation of Prokr1 1 0.18 0.89 0.68
31 INT74599 YY1 Negative_regulation of ADCY1 2 0.36 0.31 0.67
32 INT162224 Grin1 Positive_regulation of Gene_expression of Gria1 1 0.27 0.07 0.66
33 INT162223 Grin1 Positive_regulation of Localization of Gria2 1 0.23 0.07 0.66
34 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
35 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57
36 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56
37 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 1 0.00 0 0.56
38 INT210830 OPRM1 Negative_regulation of ADCY1 1 0.00 0.06 0.55
39 INT312751 Phosphorylation of Gria1 Positive_regulation of GRIA1 1 0.18 0.22 0.55
40 INT259184 Binding of Gria2 and Gria1 2 0.26 0.28 0.54
41 INT311521 Gnrhr Positive_regulation of Gene_expression of Gria1 1 0.00 0.54 0.54
42 INT32908 Binding of ADCY1 and Drd2 1 0.00 0 0.54
43 INT64744 OR5D2P Negative_regulation of ADCY1 1 0.00 0 0.54
44 INT311522 Gnrhr Positive_regulation of Transcription of Gria1 1 0.00 0.54 0.54
45 INT291386 Cntf Regulation of Gene_expression of Gria2 1 0.11 0.13 0.53
46 INT349130 Phosphorylation of Gria1 Positive_regulation of Shisa9 1 0.00 0.49 0.52
47 INT322809 Binding of GRIA3 and RS1 1 0.01 0.43 0.51
48 INT93265 Binding of ADCY1 and OPRL1 1 0.13 0.17 0.51
49 INT169083 Binding of GRIA3 and MOCOS 2 0.07 0.51 0.5
50 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
51 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
52 INT259183 Gria1 Positive_regulation of Phosphorylation of Gria2 1 0.30 0.39 0.49
53 INT273110 Bdnf Regulation of Positive_regulation of Gria1 1 0.43 0 0.47
54 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
55 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
56 INT89647 OPRM1 Regulation of ADCY1 1 0.09 0.09 0.47
57 INT258584 ADORA3 Negative_regulation of ADCY1 1 0.02 0 0.44
58 INT111275 BRI3P1 Positive_regulation of Negative_regulation of ADCY1 1 0.06 0 0.44
59 INT89649 INSRR Regulation of ADCY1 1 0.00 0.07 0.44
60 INT111274 C2 Positive_regulation of Negative_regulation of ADCY1 1 0.14 0 0.44
61 INT73832 Pld1 Positive_regulation of ADCY1 1 0.00 0.16 0.44
62 INT86069 Positive_regulation of Gria1 Positive_regulation of Gene_expression of Fos 1 0.11 0.3 0.42
63 INT127543 Gria1 Positive_regulation of Gene_expression of Cryge 1 0.00 0.35 0.42
64 INT74713 Binding of Gria1 and Olr1868 1 0.00 0 0.42
65 INT127546 Gria1 Positive_regulation of Gene_expression of Kcnab3 1 0.02 0.35 0.42
66 INT68526 Binding of ADCY1 and DIO2 1 0.01 0.07 0.41
67 INT68527 Binding of ADCY1 and OPRD1 1 0.06 0.07 0.41
68 INT105170 OPRD1 Positive_regulation of Phosphorylation of ADCY1 1 0.08 0 0.41
69 INT11425 OR2A12 Positive_regulation of Negative_regulation of ADCY1 1 0.01 0 0.4
70 INT105169 RAF1 Regulation of Positive_regulation of ADCY1 1 0.12 0 0.4
71 INT233513 Pklr Negative_regulation of Localization of Il10 1 0.04 1.12 0.39
72 INT152453 Gsk3b Regulation of Nfkb1 1 0.02 1.68 0.36
73 INT270220 Negative_regulation of Ephb1 Negative_regulation of Positive_regulation of Pla2g4a 1 0.13 1 0.36
74 INT66369 Pomc Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
75 INT84600 Binding of Avp and Aqp2 1 0.17 0 0.35
76 INT321366 Gsk3b Regulation of Gene_expression of CYP8B1 1 0.01 0.21 0.33
77 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32
78 INT342810 Binding of Adarb1 and Gsk3b 1 0.00 0.36 0.3
79 INT339001 GSX1 Positive_regulation of ADCY1 1 0.01 0 0.29
80 INT141438 Gnai2 Positive_regulation of Localization of ADCY1 1 0.01 0.43 0.29
81 INT210828 POMC Positive_regulation of ADCY1 1 0.03 0.34 0.28
82 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28
83 INT265831 BGN Positive_regulation of ADCY1 1 0.01 0.41 0.27
84 INT103482 RARB Positive_regulation of Gene_expression of Gria1 1 0.00 0 0.27
85 INT93952 CGA Positive_regulation of ADCY1 1 0.03 0 0.27
86 INT293118 Avp Regulation of Aqp2 1 0.04 0.7 0.27
87 INT233515 Pklr Positive_regulation of Gene_expression of Tnf 1 0.05 1.12 0.27
88 INT93953 Negative_regulation of CGA Positive_regulation of ADCY1 1 0.03 0 0.27
89 INT103483 BDNF Positive_regulation of Gene_expression of Gria1 1 0.03 0 0.26
90 INT223042 AR Positive_regulation of ADCY1 1 0.01 0.41 0.25
91 INT223036 SLURP1 Regulation of Positive_regulation of ADCY1 1 0.00 0.42 0.25
92 INT51432 Gria1 Positive_regulation of Trib3 1 0.04 0 0.25
93 INT273109 Bdnf Positive_regulation of Gene_expression of Gria1 1 0.66 0.07 0.24
94 INT34499 ADRB3 Positive_regulation of ADCY1 1 0.07 0.19 0.23
95 INT354544 Avp Positive_regulation of ADCY1 1 0.24 2.23 0.22
96 INT224130 Positive_regulation of Adora2a Positive_regulation of ADCY1 1 0.01 0.11 0.22
97 INT7332 CALM3 Positive_regulation of ADCY1 1 0.46 0.13 0.21
98 INT287763 Binding of Gria2 and Ap3m1 1 0.02 0.33 0.21
99 INT311527 Binding of Grin2a and Gria1 1 0.01 0 0.21
100 INT224133 Negative_regulation of Adora2b Positive_regulation of ADCY1 1 0.01 0.1 0.2
101 INT224134 Adora2b Positive_regulation of ADCY1 1 0.01 0.1 0.2
102 INT216841 TCIRG1 Negative_regulation of ADCY1 1 0.01 0.35 0.18
103 INT351442 Gria2 Regulation of Gene_expression of Casp3 1 0.01 0 0.18
104 INT287764 Binding of Gria2 and Nsf 1 0.34 0.33 0.18
105 INT261401 Binding of Gsk3b and ADHD1 1 0.00 1.62 0.18
106 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18
107 INT216842 ATP6V0A1 Negative_regulation of ADCY1 1 0.01 0.35 0.18
108 INT74600 Negative_regulation of YY1 Negative_regulation of ADCY1 1 0.36 0.25 0.17
109 INT185516 Binding of Igfbp2 and Csf2 1 0.14 0.29 0.17
110 INT273097 Binding of Bdnf and Gria1 1 0.39 0.17 0.16
111 INT269758 Negative_regulation of IGF1 Negative_regulation of Positive_regulation of IGFBP2 1 0.10 2.15 0.16
112 INT261521 Binding of ADCY1 and GLUL 1 0.01 0.09 0.15
113 INT241772 AVP Positive_regulation of ADCY1 1 0.09 1.08 0.15
114 INT77122 WDTC1 Positive_regulation of Negative_regulation of ADCY1 1 0.06 0.39 0.15
115 INT311526 Gria1 Regulation of Gene_expression of Grin2a 1 0.01 0.32 0.15
116 INT271071 Binding of ACTA1 and Hypism 1 0.00 1.54 0.15
117 INT293124 Agtr1a Regulation of Gene_expression of Aqp2 1 0.17 0.36 0.14
118 INT293117 Agt Regulation of Gene_expression of Aqp2 1 0.23 0.36 0.14
119 INT61998 GNPTAB Positive_regulation of ADCY1 1 0.03 0 0.13
120 INT52711 BSG Regulation of ADCY1 1 0.01 0.1 0.12
121 INT260497 VEGFA Positive_regulation of Gria2 1 0.03 1.08 0.12
122 INT141426 ANTXRL Negative_regulation of ADCY1 1 0.00 0.41 0.11
123 INT75029 Gstm1 Regulation of Gene_expression of Gstm2 1 0.00 0.1 0.1
124 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1
125 INT190246 TARBP2 Positive_regulation of PKLR 1 0.01 0.41 0.1
126 INT32546 Gsk3b Negative_regulation of Localization of Gnrh1 1 0.05 0 0.1
127 INT32547 Gsk3b Negative_regulation of Localization of LH 1 0.04 0 0.1
128 INT273108 Gria1 Regulation of Positive_regulation of Gria2 1 0.04 0.09 0.1
129 INT75035 Gsta2 Regulation of Gene_expression of Gstm1 1 0.00 0.1 0.1
130 INT75027 Gstm1 Regulation of Gene_expression of Gsta2 1 0.00 0.1 0.1
131 INT72302 Regulation of ADRA2C Regulation of ADCY1 1 0.02 0.14 0.09
132 INT72304 ADRA2C Regulation of ADCY1 1 0.02 0.14 0.09
133 INT268925 Igfbp2 Negative_regulation of Phosphorylation of Mapk14 1 0.01 0.35 0.08
134 INT273104 Mtor Negative_regulation of Gene_expression of Gria1 1 0.46 0.15 0.08
135 INT197776 Pla2g10 Regulation of Pla2g4a 1 0.18 0.61 0.08
136 INT273115 Bdnf Negative_regulation of Gene_expression of Gria1 1 0.47 0.15 0.08
137 INT265256 Binding of Gria2 and Cdh2 2 0.02 0.17 0.07
138 INT234802 Binding of AQP2 and AVPR2 2 0.15 0.84 0.07
139 INT218829 Ppp1cc Regulation of Phosphorylation of Gria1 1 0.20 0.63 0.07
140 INT233521 Binding of Pklr and Prokr1 1 0.17 0.44 0.07
141 INT51273 IGF1 Positive_regulation of IGFBP2 1 0.37 0.13 0.06
142 INT145622 Binding of PKLR and UGT1A3 1 0.01 0 0.06
143 INT145623 Binding of PKLR and UGT2B4 1 0.02 0 0.06
144 INT145626 Binding of PKLR and UGT1A1 1 0.02 0 0.06
145 INT346752 Binding of Dlg1 and Gria1 1 0.02 0 0.06
146 INT145621 Binding of PKLR and UGT2B7 1 0.02 0 0.06
147 INT145624 Binding of PKLR and UGT1A9 1 0.02 0 0.06
148 INT346754 Binding of Dlg4 and Gria2 1 0.02 0 0.06
149 INT218830 Camk2a Regulation of Phosphorylation of Gria1 1 0.36 0.63 0.06
150 INT145625 Binding of PKLR and UGT2B17 1 0.01 0 0.06
151 INT293122 Avp Regulation of Gene_expression of Aqp2 1 0.04 0.81 0.05
152 INT190247 TARBP2 Negative_regulation of PKLR 1 0.01 0.2 0.05
153 INT8928 Negative_regulation of Trpc4 Negative_regulation of Positive_regulation of Acta1 1 0.02 0.18 0.05
154 INT206685 IMPA1 Positive_regulation of HBS1L 1 0.00 0.24 0.04
155 INT89385 INS Positive_regulation of Phosphorylation of PTK2B 1 0.15 0.59 0.04
156 INT195837 Tlr4 Positive_regulation of Pla2g4a 1 0.01 0.44 0.03
157 INT289101 Binding of KCNA1 and LEF1 1 0.00 2.58 0.03
158 INT273102 Bdnf Regulation of Gria1 1 0.30 0.08 0.03
159 INT273095 Rbm14 Regulation of Gria1 1 0.00 0.07 0.03
160 INT273105 Mtor Regulation of Gria1 1 0.29 0.07 0.03
161 INT241775 AVP Positive_regulation of Gene_expression of AQP2 1 0.08 0.17 0
162 INT337402 LEF1 Positive_regulation of E2F1 1 0.11 0 0
163 INT331237 Negative_regulation of IMPA1 Negative_regulation of Itpr3 1 0.00 0.52 0
164 INT278495 IGFBP2 Positive_regulation of Gene_expression of IGF1 1 0.20 0 0
165 INT337415 Negative_regulation of MIR203 Positive_regulation of Positive_regulation of LEF1 1 0.03 0.25 0
166 INT337405 MIR203 Regulation of LEF1 1 0.02 0.31 0
167 INT265258 Positive_regulation of gr Regulation of Gria2 1 0.01 0 0
168 INT337411 Negative_regulation of MIR203 Positive_regulation of Gene_expression of LEF1 1 0.04 0.25 0
169 INT344893 Binding of ADCY1 and Ptger4 1 0.00 0 0
170 INT346746 Binding of Cacng2 and Gria2 1 0.21 0.18 0
171 INT289102 KCNA1 Negative_regulation of Gene_expression of LEF1 1 0.00 0.44 0
172 INT289098 KCNA1 Regulation of LEF1 1 0.00 0.67 0
173 INT160810 Gria2 Regulation of Shisa9 1 0.00 0 0
174 INT337417 MIR203 Negative_regulation of LEF1 1 0.04 0.57 0
175 INT220822 Binding of Myc and LEF1 1 0.26 0.08 0
176 INT88409 BMP7 Positive_regulation of Gene_expression of ACTA1 1 0.09 0 0
177 INT293114 Fig4 Regulation of Gene_expression of Aqp2 1 0.08 1.53 0
178 INT220766 Binding of MAX and LEF1 1 0.40 0.08 0
179 INT234803 AVP Regulation of AQP2 1 0.11 1.3 0
180 INT281610 Positive_regulation of Akt1 Positive_regulation of Gsk3b 1 0.02 0.12 0
181 INT346764 Binding of RBM10 and Gria2 1 0.01 0.18 0
182 INT234796 Binding of AQP2 and AVP 1 0.15 1.1 0
183 INT303004 Adm Positive_regulation of Gsk3b 1 0.04 0.97 0
184 INT344892 Binding of ADCY1 and Ptger2 1 0.01 0 0
185 INT289100 KCNA1 Regulation of Gene_expression of LEF1 1 0.00 0.68 0
186 INT301639 Positive_regulation of Mlxipl Positive_regulation of Gene_expression of Pklr 1 0.03 0.52 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to lithium ion. They are ordered first by their pain relevance and then by number of times they were reported in response to lithium ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
2 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96
3 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9
4 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
5 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
6 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
7 INT56525 Gene_expression of Gria2 74 0.75 23.15 28.6
8 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
9 INT187513 Positive_regulation of Pla2g4a 5 0.62 34.09 18.22
10 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
11 INT195831 Phosphorylation of Pla2g4a 15 0.74 34.43 17.14
12 INT12617 Regulation of ADCY1 41 0.61 7.38 15.94
13 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
14 INT114510 Positive_regulation of Gria2 36 0.57 14.91 14.85
15 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
16 INT49538 Binding of Gria1 22 0.47 2.66 13.35
17 INT11429 Gene_expression of ADCY1 26 0.74 5.89 11.93
18 INT270238 Localization of Pla2g4a 1 0.72 17.99 11.35
19 INT40486 Positive_regulation of Positive_regulation of ADCY1 20 0.48 4.29 11.33
20 INT259165 Phosphorylation of Gria2 4 0.65 11.65 11.07
21 INT57069 Regulation of Gria2 28 0.44 10.11 11.06
22 INT12620 Negative_regulation of Negative_regulation of ADCY1 16 0.44 2.98 10.1
23 INT8072 Localization of Gria1 17 0.75 2.62 10.04
24 INT259169 Positive_regulation of Phosphorylation of Gria2 3 0.40 9.98 9.34
25 INT54681 Negative_regulation of Positive_regulation of ADCY1 16 0.38 2.7 8.14
26 INT78766 Negative_regulation of Gria2 20 0.52 6.27 8.12
27 INT114509 Transcription of Gria2 10 0.58 0.75 7.27
28 INT57023 Negative_regulation of Gene_expression of Gria1 20 0.58 6.92 7.17
29 INT120298 Negative_regulation of Phosphorylation of Gria1 6 0.57 8.99 6.68
30 INT94927 Transcription of Gria1 12 0.69 3.14 5.94
31 INT57068 Regulation of Gene_expression of Gria2 12 0.36 3.76 5.44
32 INT80881 Phosphorylation of ADCY1 7 0.69 1.22 5.29
33 INT259167 Negative_regulation of Phosphorylation of Gria2 2 0.34 5.24 5.13
34 INT85946 Localization of Gria2 10 0.61 1.23 5.09
35 INT26042 Binding of Gria2 20 0.40 4.88 5.04
36 INT114511 Positive_regulation of Gene_expression of Gria2 14 0.41 3.9 4.71
37 INT14574 Positive_regulation of Negative_regulation of ADCY1 9 0.66 2.45 4.39
38 INT28734 Gene_expression of Reln 7 0.74 5.76 4.33
39 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
40 INT92902 Negative_regulation of Positive_regulation of Gria1 6 0.57 1.06 4.1
41 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
42 INT162125 Gene_expression of Pla2g4a 4 0.54 7.69 3.75
43 INT87281 Localization of ADCY1 7 0.64 1.84 3.42
44 INT84564 Regulation of Positive_regulation of Gria1 2 0.33 1.86 3.3
45 INT51427 Positive_regulation of Positive_regulation of Gria1 11 0.45 1.33 3.28
46 INT270224 Positive_regulation of Positive_regulation of Pla2g4a 1 0.62 6.63 3.22
47 INT13179 Regulation of Positive_regulation of ADCY1 5 0.34 0.89 3.08
48 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
49 INT59309 Negative_regulation of Gene_expression of ADCY1 3 0.42 1.04 2.98
50 INT30815 Binding of ADCY1 7 0.36 0.21 2.79
51 INT169088 Gene_expression of GRIA3 7 0.76 1.32 2.67
52 INT80884 Positive_regulation of Phosphorylation of ADCY1 4 0.43 0.24 2.64
53 INT11426 Positive_regulation of Gene_expression of ADCY1 5 0.29 0.68 2.63
54 INT131973 Positive_regulation of Transcription of Gria1 3 0.49 0.35 2.62
55 INT114513 Negative_regulation of Gene_expression of Gria2 8 0.48 0.89 2.61
56 INT84599 Gene_expression of Aqp2 31 0.77 22.58 2.54
57 INT153733 Negative_regulation of Transcription of Gria2 1 0.47 0 2.39
58 INT270235 Negative_regulation of Phosphorylation of Pla2g4a 1 0.39 3.4 2.34
59 INT152076 Negative_regulation of Pla2g4a 3 0.55 3.22 2.21
60 INT195828 Positive_regulation of Phosphorylation of Pla2g4a 3 0.45 5.05 2.12
61 INT64125 Positive_regulation of Localization of Igfbp2 1 0.38 0.18 2.02
62 INT259164 Positive_regulation of Binding of Gria2 4 0.40 2 1.91
63 INT265064 Binding of Reln 1 0.02 2.7 1.83
64 INT84595 Negative_regulation of Aqp2 11 0.58 4.88 1.78
65 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
66 INT166819 Gene_expression of IMPA1 12 0.65 3.85 1.77
67 INT265066 Positive_regulation of Reln 1 0.02 1.59 1.72
68 INT28735 Localization of Reln 2 0.12 1.49 1.7
69 INT322821 Binding of GRIA3 1 0.47 2.06 1.67
70 INT87289 Positive_regulation of Localization of ADCY1 3 0.43 0.36 1.65
71 INT114508 Positive_regulation of Negative_regulation of Gria2 2 0.36 0.98 1.64
72 INT80890 Negative_regulation of Phosphorylation of ADCY1 2 0.36 0.24 1.57
73 INT72310 Regulation of Regulation of ADCY1 6 0.24 1.24 1.55
74 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
75 INT312743 Regulation of Phosphorylation of Gria1 2 0.51 2.01 1.5
76 INT270223 Negative_regulation of Localization of Pla2g4a 1 0.39 1.83 1.5
77 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
78 INT71918 Gene_expression of ACTA1 16 0.75 7.73 1.45
79 INT159312 Regulation of Reln 4 0.43 1.79 1.4
80 INT65179 Regulation of Regulation of Gria1 2 0.07 0.37 1.39
81 INT61066 Gene_expression of Igfbp2 55 0.77 2.01 1.35
82 INT122345 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0 1.34
83 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
84 INT78692 Regulation of PTK2B 2 0.47 0.29 1.28
85 INT80887 Negative_regulation of Regulation of ADCY1 3 0.35 0.1 1.26
86 INT100328 Gene_expression of AQP2 6 0.75 2.41 1.21
87 INT162222 Positive_regulation of Positive_regulation of Gria2 3 0.38 0.64 1.19
88 INT9319 Localization of Igfbp2 6 0.80 1.13 1.17
89 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15
90 INT79557 Localization of Aqp2 5 0.73 2 1.13
91 INT295165 Negative_regulation of Adcy1 1 0.09 1.3 1.13
92 INT34141 Positive_regulation of IMPA1 8 0.50 2.38 1.12
93 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11
94 INT322822 Regulation of GRIA3 4 0.61 1.19 1.11
95 INT166818 Positive_regulation of Gene_expression of IMPA1 3 0.36 0.99 1.06
96 INT60286 Gene_expression of PKLR 5 0.65 2.14 1.04
97 INT72868 Transcription of ADCY1 4 0.57 0.69 1.04
98 INT195832 Regulation of Phosphorylation of Pla2g4a 3 0.34 2.91 1.02
99 INT162126 Positive_regulation of Gene_expression of Pla2g4a 4 0.42 2.52 1.01
100 INT116646 Regulation of Negative_regulation of Gsk3b 2 0.44 0.39 0.99
101 INT120408 Localization of PKLR 1 0.01 0.8 0.99
102 INT122347 Transcription of Hsd3b1 1 0.52 0 0.99
103 INT84597 Transcription of Aqp2 3 0.55 2.11 0.98
104 INT270236 Regulation of Localization of Pla2g4a 1 0.24 1.68 0.93
105 INT270231 Regulation of Positive_regulation of Pla2g4a 1 0.24 1.92 0.92
106 INT80871 Negative_regulation of Binding of ADCY1 1 0.03 0.1 0.91
107 INT261360 Binding of Gsk3b 5 0.36 2.85 0.9
108 INT84598 Regulation of Aqp2 13 0.45 4.28 0.86
109 INT171406 Gene_expression of Pklr 3 0.65 2.75 0.86
110 INT121774 Binding of ACTA1 4 0.47 2.31 0.85
111 INT270226 Negative_regulation of Positive_regulation of Pla2g4a 1 0.38 2.34 0.84
112 INT92862 Positive_regulation of Pklr 1 0.02 0.06 0.83
113 INT108348 Positive_regulation of Aqp2 10 0.68 4.94 0.82
114 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
115 INT66365 Positive_regulation of Gene_expression of Gsk3b 2 0.07 0.95 0.81
116 INT64126 Negative_regulation of Igfbp2 2 0.33 0.46 0.8
117 INT116644 Phosphorylation of Gsk3b 4 0.61 0.68 0.78
118 INT34144 Localization of IMPA1 3 0.37 0.88 0.76
119 INT149238 Positive_regulation of Gene_expression of Aqp2 5 0.66 3.07 0.73
120 INT241788 Positive_regulation of Gene_expression of AQP2 3 0.67 1.26 0.7
121 INT322816 Transcription of GRIA3 2 0.71 0.75 0.7
122 INT157073 Positive_regulation of PKLR 6 0.36 5.48 0.69
123 INT322819 Regulation of Binding of GRIA3 1 0.61 1.07 0.68
124 INT162221 Positive_regulation of Localization of Gria2 2 0.38 0.09 0.61
125 INT349122 Regulation of Phosphorylation of Gria2 1 0.28 0.57 0.61
126 INT84596 Negative_regulation of Gene_expression of Aqp2 3 0.58 8.49 0.6
127 INT84594 Negative_regulation of Transcription of Aqp2 1 0.43 0 0.59
128 INT34143 Regulation of IMPA1 14 0.44 4.83 0.58
129 INT259166 Protein_catabolism of Gria2 2 0.70 0.47 0.58
130 INT200893 Negative_regulation of Transcription of Gria1 2 0.08 0.6 0.58
131 INT259171 Protein_catabolism of Gria1 1 0.76 0.48 0.58
132 INT230974 Positive_regulation of Gene_expression of GRIA3 2 0.49 0 0.57
133 INT165848 Protein_catabolism of ADCY1 1 0.25 0.28 0.57
134 INT100322 Localization of AQP2 5 0.80 0.56 0.56
135 INT57201 Localization of ACTA1 2 0.73 1.53 0.56
136 INT270227 Positive_regulation of Localization of Pla2g4a 1 0.45 1.31 0.56
137 INT165845 Positive_regulation of Transcription of ADCY1 1 0.26 0.36 0.55
138 INT60289 Negative_regulation of PKLR 5 0.21 1.75 0.53
139 INT120399 Positive_regulation of Phosphorylation of PKLR 1 0.01 0.44 0.53
140 INT73301 Positive_regulation of ACTA1 2 0.01 0.58 0.51
141 INT120389 Phosphorylation of PKLR 2 0.11 1.81 0.51
142 INT230982 Positive_regulation of Transcription of Gria2 1 0.28 0.65 0.51
143 INT110905 Regulation of Negative_regulation of ADCY1 1 0.59 0 0.48
144 INT75024 Positive_regulation of Gstm1 4 0.31 0.49 0.46
145 INT122348 Regulation of Hsd3b1 1 0.60 0 0.46
146 INT270229 Binding of Pla2g4a 1 0.29 1.23 0.45
147 INT109920 Positive_regulation of PTK2B 5 0.43 2.21 0.43
148 INT73302 Transcription of ACTA1 2 0.02 0.55 0.43
149 INT349121 Negative_regulation of Binding of Gria2 1 0.22 0.59 0.43
150 INT352667 Positive_regulation of Transcription of GRIA3 1 0.08 0.39 0.42
151 INT352661 Positive_regulation of GRIA3 1 0.12 0.33 0.41
152 INT114512 Positive_regulation of Regulation of Gria2 1 0.33 0 0.41
153 INT149235 Positive_regulation of Transcription of Aqp2 1 0.45 0.72 0.4
154 INT149244 Positive_regulation of Localization of Aqp2 1 0.49 0.72 0.4
155 INT109922 Negative_regulation of PTK2B 3 0.26 1.63 0.39
156 INT139668 Binding of Igfbp2 3 0.18 0.98 0.39
157 INT351452 Negative_regulation of Positive_regulation of Gria2 1 0.26 0.64 0.39
158 INT8923 Positive_regulation of Acta1 1 0.18 0.96 0.39
159 INT100324 Regulation of Localization of AQP2 1 0.27 0.19 0.38
160 INT157836 Regulation of Gene_expression of Aqp2 9 0.57 8.37 0.37
161 INT100323 Regulation of Gene_expression of AQP2 1 0.45 0.18 0.36
162 INT109919 Positive_regulation of Positive_regulation of PTK2B 1 0.31 0.09 0.35
163 INT60287 Regulation of PKLR 1 0.15 0.32 0.35
164 INT66364 Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
165 INT111230 Transcription of LEF1 3 0.30 1.72 0.33
166 INT79558 Binding of Aqp2 2 0.31 0.25 0.33
167 INT140349 Positive_regulation of Localization of Pklr 1 0.01 0.38 0.33
168 INT140352 Localization of Pklr 1 0.02 0.38 0.33
169 INT169090 Regulation of Gene_expression of GRIA3 2 0.61 0.46 0.32
170 INT22882 Negative_regulation of IMPA1 10 0.57 5.19 0.31
171 INT34142 Positive_regulation of Localization of IMPA1 1 0.24 0 0.31
172 INT322820 Localization of GRIA3 1 0.74 0.31 0.31
173 INT61065 Positive_regulation of Igfbp2 9 0.69 1.13 0.3
174 INT75006 Gene_expression of Gstm1 6 0.45 2.19 0.29
175 INT9326 Regulation of Igfbp2 4 0.61 0.99 0.29
176 INT48727 Gene_expression of IGFBP2 7 0.46 1.94 0.28
177 INT60288 Regulation of Gene_expression of PKLR 1 0.15 0.32 0.28
178 INT268924 Negative_regulation of Gene_expression of Igfbp2 1 0.02 0.8 0.27
179 INT200894 Positive_regulation of Adcy1 1 0.06 0.23 0.26
180 INT345254 Positive_regulation of Localization of Gsk3b 2 0.01 0.91 0.24
181 INT316938 Negative_regulation of Regulation of Gria1 1 0.32 0.23 0.24
182 INT51109 Gene_expression of Adcy1 2 0.09 0.15 0.23
183 INT125877 Binding of PKLR 2 0.04 0.26 0.22
184 INT200897 Negative_regulation of Localization of Gria1 1 0.07 0 0.22
185 INT116647 Positive_regulation of Phosphorylation of Gsk3b 1 0.37 0.18 0.22
186 INT322824 Regulation of Regulation of GRIA3 1 0.44 0.42 0.2
187 INT159314 Positive_regulation of Gene_expression of Reln 1 0.44 0.47 0.2
188 INT89400 Phosphorylation of PTK2B 4 0.38 1.16 0.19
189 INT9322 Transcription of Igfbp2 2 0.44 0.44 0.17
190 INT171022 Binding of IGFBP2 1 0.19 0.62 0.16
191 INT51278 Positive_regulation of IGFBP2 2 0.32 1.17 0.15
192 INT195826 Negative_regulation of Gene_expression of Pla2g4a 1 0.28 1.38 0.15
193 INT195829 Regulation of Pla2g4a 1 0.20 2.54 0.15
194 INT73303 Positive_regulation of Transcription of ACTA1 1 0.01 0.29 0.14
195 INT145096 Negative_regulation of ACTA1 1 0.43 0.28 0.14
196 INT88416 Positive_regulation of Gene_expression of ACTA1 2 0.67 1.05 0.13
197 INT89409 Negative_regulation of Phosphorylation of PTK2B 2 0.13 0.89 0.12
198 INT8926 Negative_regulation of Positive_regulation of Acta1 1 0.11 0.33 0.12
199 INT135555 Localization of PTK2B 1 0.57 0.32 0.1
200 INT309869 Regulation of Binding of Gsk3b 1 0.12 0.66 0.1
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