GO:0010243

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Name response to organic nitrogen
Categary Process
Go Slim No
Go Link GO:0010243
Unique Molecular Interactions 1189
Total Molecular Interactions 1633
Total Single Events 16162
Pain Genes Associated 55

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to organic nitrogen. They are ordered first by their pain relevance and then by number of times they were reported for response to organic nitrogen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT227157 Binding of PEBP1 and Gpm6a 1 0.00 1.28 5.52
4 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
5 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
6 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
7 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
8 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
9 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
10 INT349583 Aap Positive_regulation of Gene_expression of Cyp2e1 1 0.18 1.57 3.59
11 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
12 INT349584 Binding of Cyp2e1 and Aap 1 0.10 1.56 3.24
13 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
14 INT85042 Binding of CCT6A and MAX 1 0.00 0 3.13
15 INT30424 Penk Regulation of Localization of Sst 1 0.20 0 3.1
16 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
17 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
18 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
19 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
20 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
21 INT349589 Aap Positive_regulation of Cyp2e1 1 0.21 1.84 2.71
22 INT107812 Nppa Positive_regulation of Localization of Sst 1 0.48 0.54 2.51
23 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37
24 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
25 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
26 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
27 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
28 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
29 INT3576 Sst Negative_regulation of Localization of Gh1 6 0.23 0 2.13
30 INT18593 Binding of Sst and Fdft1 2 0.11 0.08 2.12
31 INT85041 Binding of IGHG3 and MAX 1 0.00 0 2.09
32 INT18355 Penk Positive_regulation of Localization of Sst 1 0.31 0 2.04
33 INT13430 Abat Positive_regulation of Localization of Sst 2 0.33 0 1.94
34 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
35 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
36 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
37 INT13979 Gast Positive_regulation of Localization of Sst 3 0.69 0.05 1.75
38 INT31534 Binding of Sst and Oprl1 2 0.16 0.53 1.74
39 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
40 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
41 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
42 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
43 INT18592 Sst Regulation of Localization of Acot1 2 0.22 0 1.61
44 INT107815 Gene_expression of Sst Positive_regulation of Localization of Nppa 1 0.52 0.27 1.57
45 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
46 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
47 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
48 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54
49 INT7797 Akr1d1 Regulation of Sst 1 0.02 0 1.54
50 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
51 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
52 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
53 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53
54 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
55 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
56 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
57 INT107813 Sst Negative_regulation of Localization of Nppa 1 0.44 0.2 1.46
58 INT12691 SST Negative_regulation of Localization of POMC 3 0.24 1.24 1.45
59 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
60 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
61 INT19013 Ghsr Negative_regulation of Localization of Sst 1 0.15 0 1.44
62 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
63 INT79745 Gtf3a Positive_regulation of Positive_regulation of Sst 1 0.09 0 1.4
64 INT26812 SST Regulation of Localization of OXT 1 0.40 0.57 1.37
65 INT18589 Gast Regulation of Localization of Sst 1 0.61 0.15 1.37
66 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
67 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
68 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 1 0.01 0.81 1.31
69 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
70 INT124925 Negative_regulation of Slc6a1 Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
71 INT96707 Ntf3 Positive_regulation of Localization of SST 1 0.01 0 1.3
72 INT96708 Bdnf Positive_regulation of Localization of SST 1 0.01 0 1.3
73 INT138211 Mzb1 Regulation of Sst 1 0.05 0.41 1.29
74 INT138212 Mzb1 Regulation of Localization of Sst 1 0.12 0.41 1.29
75 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
76 INT7284 Abat Regulation of Sst 1 0.18 0 1.28
77 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
78 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
79 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27
80 INT8409 IL1A Positive_regulation of Positive_regulation of Vip 1 0.01 0.63 1.27
81 INT30744 Sst Regulation of Cck 1 0.28 0.43 1.27
82 INT239640 Sst Positive_regulation of Ltp 1 0.04 0.23 1.26
83 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
84 INT3575 Sst Regulation of Localization of Gnrhr 2 0.24 0 1.24
85 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
86 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
87 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
88 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
89 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
90 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
91 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
92 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
93 INT30871 Abat Regulation of Localization of Sst 1 0.13 0 1.17
94 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
95 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
96 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
97 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
98 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
99 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
100 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
101 INT60133 MME Negative_regulation of SST 1 0.10 0 1.12
102 INT4753 Sst Negative_regulation of Localization of Calca 1 0.39 0.06 1.1
103 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
104 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
105 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
106 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
107 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
108 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
109 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
110 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07
111 INT85040 Positive_regulation of Binding of CCT6A and MAX 1 0.00 0 1.06
112 INT30575 SST Negative_regulation of Localization of Pomc 1 0.00 0.71 1.06
113 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
114 INT8410 IL1A Positive_regulation of Vip 1 0.02 0.68 1.05
115 INT85039 Binding of GPM6A and MAX 1 0.00 0 1.05
116 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04
117 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 0.00 1.05 1.04
118 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
119 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03
120 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
121 INT40715 Binding of SST and Penk 1 0.10 0 1.02
122 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
123 INT30378 Binding of Sst and Penk 1 0.28 0.52 1.01
124 INT51261 Calca Negative_regulation of Sst 1 0.20 0.08 1.01
125 INT119914 Olr1714 Negative_regulation of Nos1 1 0.02 0.47 1.01
126 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
127 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
128 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
129 INT52435 Positive_regulation of Binding of Sst and Fdft1 1 0.09 0.08 0.98
130 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
131 INT292530 Il10 Negative_regulation of Localization of Il1a 1 0.06 1.09 0.97
132 INT159111 Il1a Regulation of Gene_expression of Il1b 1 0.49 0.38 0.97
133 INT89828 Atp4b Positive_regulation of Localization of Grip2 1 0.10 0.54 0.97
134 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
135 INT7283 Binding of Sst and Abat 1 0.23 0 0.96
136 INT240123 MIR885 Negative_regulation of IL1B 1 0.01 1.57 0.96
137 INT18597 Sst Positive_regulation of Localization of Acot1 1 0.29 0 0.96
138 INT163265 Sst Negative_regulation of Tyr 1 0.00 0.22 0.95
139 INT130722 Binding of IL1B and Nfkb1 1 0.28 1.23 0.95
140 INT42482 Binding of Cpe and Pebp1 1 0.02 0 0.95
141 INT30855 Sst Negative_regulation of Localization of Sct 1 0.08 0 0.94
142 INT130725 Binding of IL1B and Il1rn 1 0.01 1.16 0.93
143 INT81919 Binding of HSF1 and IL1B 1 0.42 0.77 0.93
144 INT66536 Il1a Regulation of Gene_expression of Fos 1 0.59 0 0.91
145 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
146 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9
147 INT7793 Ptgdr Regulation of Sst 1 0.09 0 0.89
148 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
149 INT21944 Il1a Negative_regulation of Gnrh1 1 0.34 0 0.89
150 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
151 INT151630 Il1rn Negative_regulation of Dock9 1 0.03 1.33 0.88
152 INT136349 Il1b Positive_regulation of Positive_regulation of Oprl1 1 0.22 0.27 0.88
153 INT48463 Bdnf Positive_regulation of Gene_expression of Sst 1 0.25 0 0.88
154 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87
155 INT224585 IL1B Positive_regulation of IL1RN 1 0.02 1.3 0.87
156 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 0.01 1.52 0.86
157 INT270218 P2rx3 Positive_regulation of Pla2g4a 1 0.34 0.63 0.85
158 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84
159 INT30425 Penk Regulation of Sst 1 0.20 0 0.84
160 INT41156 Sst Negative_regulation of Npr1 1 0.05 0 0.84
161 INT2881 SST Negative_regulation of Positive_regulation of CCK 1 0.32 0.1 0.84
162 INT2880 SST Negative_regulation of CCK 1 0.32 0.1 0.84
163 INT10275 Il1b Positive_regulation of Gene_expression of Penk 1 0.49 0.75 0.83
164 INT84087 B3GAT1 Positive_regulation of Localization of SST 1 0.06 0 0.83
165 INT65011 IL1B Positive_regulation of PTGER2 4 0.08 0.92 0.82
166 INT74383 Sst Positive_regulation of GEM 1 0.01 0.09 0.82
167 INT155761 Binding of Nos1 and Tjp1 1 0.13 1.01 0.82
168 INT74382 Negative_regulation of Sst Positive_regulation of GEM 1 0.00 0.09 0.82
169 INT303656 SST Negative_regulation of Localization of GAST 1 0.12 1.45 0.82
170 INT155760 Binding of Nos1 and Dlg4 1 0.13 1.01 0.82
171 INT74384 Regulation of Sst Positive_regulation of GEM 1 0.00 0.09 0.82
172 INT54260 SST Regulation of GH1 1 0.18 0.06 0.81
173 INT83094 IL1B Positive_regulation of Positive_regulation of BDKRB1 1 0.45 0.2 0.81
174 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
175 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79
176 INT13427 Positive_regulation of Abat Positive_regulation of Localization of Sst 1 0.33 0 0.79
177 INT79743 Nts Positive_regulation of Positive_regulation of Sst 1 0.25 0 0.79
178 INT79742 Positive_regulation of Nts Positive_regulation of Sst 1 0.25 0 0.79
179 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
180 INT239638 Sst Regulation of Fig4 1 0.12 0.39 0.78
181 INT79741 Nts Positive_regulation of Sst 1 0.25 0 0.78
182 INT152857 PRS Regulation of Nefl 1 0.00 0.19 0.77
183 INT152833 Nefl Regulation of Prkcg 1 0.12 0.19 0.77
184 INT196575 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1a 1 0.04 0.44 0.77
185 INT107810 Sst Positive_regulation of Localization of Nppa 1 0.42 0.14 0.77
186 INT200097 Negative_regulation of Binding of Il1a and Jun 1 0.00 2.76 0.77
187 INT18402 Glp1r Regulation of Localization of Sst 1 0.19 0 0.77
188 INT152834 Nefl Regulation of Nefh 1 0.10 0.19 0.77
189 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76
190 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
191 INT40707 Sst Positive_regulation of Localization of Gnrhr 1 0.26 0 0.76
192 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
193 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
194 INT90125 Nfkb1 Regulation of Gene_expression of Nos1 1 0.17 0.39 0.76
195 INT200093 Binding of Il1a and Jun 1 0.00 2.64 0.76
196 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
197 INT90116 Nfkb1 Positive_regulation of Gene_expression of Nos1 1 0.32 0.39 0.76
198 INT135180 IL1B Positive_regulation of Gene_expression of TNFSF11 2 0.76 1.73 0.75
199 INT54802 SST Negative_regulation of Localization of Gh 1 0.01 0 0.75
200 INT54801 SST Negative_regulation of Positive_regulation of Gh 1 0.01 0 0.75

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to organic nitrogen. They are ordered first by their pain relevance and then by number of times they were reported in response to organic nitrogen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26
2 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85
3 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
4 INT1005 Localization of Sst 385 0.81 26.31 244.56
5 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6
6 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51
7 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37
8 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58
9 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
10 INT397 Localization of SST 232 0.81 58.05 101.19
11 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
12 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
13 INT1004 Regulation of Sst 140 0.62 18.52 94.84
14 INT4631 Positive_regulation of Sst 127 0.70 17.37 83.29
15 INT2155 Negative_regulation of Sst 111 0.59 16.58 77.74
16 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
17 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
18 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
19 INT6849 Localization of IL1B 229 0.81 112.56 69.63
20 INT8347 Gene_expression of SST 181 0.78 104.59 65.45
21 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
22 INT7280 Positive_regulation of Localization of Sst 97 0.70 5.64 63.37
23 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6
24 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5
25 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
26 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04
27 INT5118 Regulation of SST 97 0.62 34.35 51.74
28 INT5098 Negative_regulation of Localization of Sst 70 0.58 3.56 51.17
29 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
30 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
31 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41
32 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
33 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
34 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46
35 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
36 INT6484 Binding of IL1B 122 0.47 75.84 35.07
37 INT7282 Regulation of Localization of Sst 58 0.62 1.92 34.83
38 INT692 Negative_regulation of SST 72 0.59 28.68 34.52
39 INT691 Binding of SST 67 0.48 24.66 32.67
40 INT20307 Positive_regulation of Cyp2e1 70 0.70 23.59 32.49
41 INT9347 Localization of Il1b 58 0.81 26.13 31.53
42 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
43 INT7412 Positive_regulation of SST 71 0.70 24.44 29.48
44 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18
45 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95
46 INT7281 Binding of Sst 42 0.48 5.48 26.57
47 INT5966 Localization of Il1a 50 0.78 22.91 26.54
48 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
49 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85
50 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
51 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
52 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
53 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54
54 INT21503 Binding of Ptgs1 45 0.48 15.6 22.29
55 INT693 Negative_regulation of Localization of SST 46 0.59 8.57 21.75
56 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
57 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
58 INT17848 Binding of PTGS2 70 0.46 32.1 20.6
59 INT45840 Positive_regulation of Gene_expression of Ptgs1 35 0.50 16.07 20.49
60 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
61 INT20305 Gene_expression of Cyp2e1 53 0.78 19.75 19.54
62 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19
63 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
64 INT18457 Transcription of Sst 25 0.69 4.28 18.25
65 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24
66 INT187513 Positive_regulation of Pla2g4a 5 0.62 34.09 18.22
67 INT7414 Regulation of Localization of SST 31 0.60 4.85 17.46
68 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
69 INT195831 Phosphorylation of Pla2g4a 15 0.74 34.43 17.14
70 INT9197 Binding of PTGS1 44 0.48 18.48 16.26
71 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
72 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82
73 INT49606 Gene_expression of Il1rn 30 0.66 15.78 14.82
74 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
75 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
76 INT7413 Positive_regulation of Localization of SST 37 0.69 5.64 13.94
77 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
78 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
79 INT14098 Regulation of Gene_expression of Sst 13 0.44 4.01 12.92
80 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39
81 INT60461 Positive_regulation of Gene_expression of Il1a 40 0.61 17.23 12.35
82 INT12992 Negative_regulation of Gene_expression of Ptgs1 33 0.42 20.47 11.77
83 INT19527 Negative_regulation of Gene_expression of Il1a 26 0.51 15.4 11.58
84 INT787 Localization of Ptgs1 31 0.80 12.36 11.55
85 INT270238 Localization of Pla2g4a 1 0.72 17.99 11.35
86 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
87 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52
88 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
89 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
90 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
91 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
92 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
93 INT69321 Regulation of Gene_expression of PTGS2 27 0.61 13.27 9.53
94 INT57665 Negative_regulation of Cyp2e1 35 0.59 8.05 9.29
95 INT37896 Positive_regulation of Gene_expression of PTGS1 37 0.67 17.28 9.27
96 INT107087 Positive_regulation of Gene_expression of Cyp2e1 20 0.70 8.89 9.04
97 INT12991 Negative_regulation of Gene_expression of PTGS1 28 0.41 13.39 8.9
98 INT23264 Negative_regulation of Positive_regulation of Ptgs1 16 0.39 8.47 8.9
99 INT6573 Regulation of Negative_regulation of Ptgs1 19 0.45 6.16 8.71
100 INT14582 Negative_regulation of Negative_regulation of Sst 9 0.56 0.52 8.38
101 INT84672 Negative_regulation of Positive_regulation of Nos1 12 0.48 3.76 8.27
102 INT95317 Positive_regulation of Slc6a1 6 0.69 5.91 7.94
103 INT18455 Positive_regulation of Gene_expression of Sst 12 0.70 1.55 7.83
104 INT20234 Regulation of Gene_expression of Ptgs1 11 0.44 6.55 7.72
105 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
106 INT19475 Positive_regulation of IL1A 20 0.67 17.99 7.57
107 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
108 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34
109 INT105528 Negative_regulation of Slc6a1 7 0.57 2.79 7.32
110 INT5308 Regulation of Il1a 17 0.44 10.8 7.31
111 INT11378 Negative_regulation of Positive_regulation of IL1B 23 0.59 10.28 7.26
112 INT49751 Negative_regulation of Positive_regulation of PTGS1 12 0.45 4.73 7.23
113 INT85764 Binding of PEBP1 9 0.44 4.52 7.2
114 INT29583 Positive_regulation of Agtr2 30 0.45 21.47 7.04
115 INT7499 Negative_regulation of Positive_regulation of Sst 9 0.59 0.42 6.9
116 INT55091 Positive_regulation of Mgst1 35 0.69 10.77 6.88
117 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84
118 INT72532 Regulation of Gene_expression of Il1a 13 0.54 4.91 6.71
119 INT69980 Negative_regulation of Il1rn 11 0.33 7.75 6.7
120 INT90097 Localization of PTGS2 15 0.69 6.14 6.63
121 INT33781 Binding of Pebp1 11 0.44 1.76 6.61
122 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52
123 INT1280 Negative_regulation of Pebp1 7 0.28 2.12 6.45
124 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44
125 INT67130 Negative_regulation of Localization of Il1b 7 0.57 1.36 6.42
126 INT31598 Gene_expression of Mgst1 41 0.78 6.44 6.3
127 INT25130 Positive_regulation of Negative_regulation of Ptgs1 14 0.50 5.07 6.29
128 INT69499 Binding of Nos1 15 0.36 2.56 6.23
129 INT67656 Positive_regulation of Positive_regulation of PTGS2 12 0.46 4.83 6.17
130 INT93658 Transcription of Nos1 16 0.72 6.85 6.16
131 INT95313 Gene_expression of Slc6a1 6 0.76 3.96 6.14
132 INT17370 Negative_regulation of Negative_regulation of Ptgs1 16 0.22 6.5 6.12
133 INT24724 Positive_regulation of Gene_expression of SST 11 0.67 7.51 6.12
134 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09
135 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02
136 INT107441 Positive_regulation of Gene_expression of Il1rn 7 0.46 3.24 5.95
137 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93
138 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
139 INT48004 Positive_regulation of Negative_regulation of PTGS1 12 0.49 4.07 5.87
140 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
141 INT18401 Positive_regulation of Positive_regulation of Sst 9 0.47 0.29 5.68
142 INT84673 Localization of Nos1 19 0.80 5.01 5.62
143 INT58468 Negative_regulation of Gene_expression of IL1A 10 0.58 9.39 5.57
144 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55
145 INT10705 Binding of Il1b 9 0.36 2.8 5.53
146 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47
147 INT50197 Positive_regulation of Transcription of Il1b 11 0.50 8.95 5.41
148 INT50491 Regulation of Gene_expression of PTGS1 17 0.47 6 5.4
149 INT58338 Negative_regulation of Localization of Il1a 8 0.25 3.13 5.18
150 INT39256 Localization of PTGS1 17 0.74 6.62 5.1
151 INT69310 Negative_regulation of IL1A 10 0.43 7.83 5.05
152 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97
153 INT67195 Negative_regulation of Gene_expression of SST 7 0.42 6.98 4.88
154 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
155 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68
156 INT16047 Negative_regulation of Positive_regulation of Il1b 11 0.57 5.27 4.66
157 INT78995 Negative_regulation of Agtr2 26 0.42 13.05 4.56
158 INT62500 Transcription of Ptgs1 10 0.56 4.54 4.52
159 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5
160 INT50309 Binding of Il1a 22 0.40 5.4 4.49
161 INT59083 Positive_regulation of Gene_expression of IL1A 11 0.70 9.09 4.48
162 INT17818 Gene_expression of Agtr2 24 0.56 12.96 4.41
163 INT76683 Positive_regulation of Il1rn 9 0.51 9.3 4.41
164 INT79738 Regulation of Transcription of Sst 3 0.30 1.56 4.38
165 INT100262 Positive_regulation of Positive_regulation of Cyp2e1 7 0.50 2.39 4.31
166 INT7363 Regulation of Binding of Sst 5 0.44 1.5 4.22
167 INT52616 Negative_regulation of Positive_regulation of PTGS2 13 0.43 4.95 4.13
168 INT19190 Regulation of Localization of IL1B 14 0.50 8.71 4.12
169 INT64864 Gene_expression of PLA2G4A 18 0.77 10.45 4.09
170 INT61118 Gene_expression of Nefl 11 0.75 4.02 4.02
171 INT17819 Regulation of Agtr2 10 0.51 9.33 3.9
172 INT14930 Regulation of Gene_expression of SST 12 0.45 6.86 3.89
173 INT20303 Regulation of Cyp2e1 11 0.61 2.46 3.84
174 INT79096 Binding of Cyp2e1 12 0.48 4.41 3.8
175 INT19189 Localization of IL1A 14 0.78 9.02 3.78
176 INT18456 Positive_regulation of Transcription of Sst 5 0.49 1.09 3.78
177 INT162125 Gene_expression of Pla2g4a 4 0.54 7.69 3.75
178 INT117773 Positive_regulation of Phosphorylation of Ptk2 9 0.69 0.89 3.71
179 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65
180 INT83646 Binding of Il1rn 12 0.37 4.41 3.51
181 INT134875 Phosphorylation of Nos1 5 0.70 1.21 3.44
182 INT122997 Phosphorylation of Rps6kb1 46 0.72 9.92 3.43
183 INT69990 Negative_regulation of Nefl 11 0.59 2.82 3.38
184 INT40232 Transcription of Il1rn 8 0.53 9.6 3.37
185 INT38032 Protein_catabolism of SST 5 0.98 2.23 3.34
186 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
187 INT21572 Gene_expression of Pebp1 9 0.71 2.52 3.3
188 INT41742 Negative_regulation of Gene_expression of Sst 4 0.43 0.78 3.27
189 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24
190 INT270224 Positive_regulation of Positive_regulation of Pla2g4a 1 0.62 6.63 3.22
191 INT54619 Negative_regulation of Positive_regulation of Il1a 6 0.42 5.68 3.12
192 INT52694 Negative_regulation of Positive_regulation of Ptgs2 9 0.43 4.72 3.11
193 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
194 INT255307 Phosphorylation of Mgst1 5 0.14 0.12 3.05
195 INT228677 Negative_regulation of Phosphorylation of Rps6kb1 24 0.51 3.88 2.97
196 INT10265 Regulation of Regulation of Sst 6 0.33 0.35 2.91
197 INT75499 Positive_regulation of Positive_regulation of CDKN1A 12 0.60 7.28 2.84
198 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8
199 INT6479 Negative_regulation of Binding of IL1B 10 0.43 5.1 2.78
200 INT16447 Binding of IL1A 10 0.45 4.01 2.78
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