GO:0010259

From wiki-pain
Jump to: navigation, search
Name multicellular organismal aging
Categary Process
Go Slim No
Go Link GO:0010259
Unique Molecular Interactions 324
Total Molecular Interactions 446
Total Single Events 5121
Pain Genes Associated 20

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for multicellular organismal aging. They are ordered first by their pain relevance and then by number of times they were reported for multicellular organismal aging. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT289979 Binding of Helt and Negative_regulation of Maoa 1 0.00 0.17 3.14
2 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
3 INT142527 Binding of Slc1a2 and Slc1a3 2 0.31 0.12 2.13
4 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
5 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
6 INT334345 Binding of GRP and Helt 1 0.02 0 1.79
7 INT142073 Binding of Helt and Nrm 1 0.00 0 1.74
8 INT63939 Vta1 Positive_regulation of Th 1 0.14 0 1.61
9 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
10 INT40887 Penk Regulation of Th 1 0.04 0 1.53
11 INT6976 Helt Regulation of Gene_expression of St8sia1 1 0.00 0.07 1.45
12 INT106070 Positive_regulation of Oprl1 Positive_regulation of TH 1 0.13 0.15 1.36
13 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
14 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
15 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
16 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
17 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
18 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
19 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
20 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
21 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
22 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
23 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
24 INT106069 TH Positive_regulation of Th 1 0.07 0.16 1.14
25 INT88446 Uncx Positive_regulation of Th 1 0.13 0 1.1
26 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09
27 INT31549 Binding of Dbh and Vip 1 0.32 0 1.08
28 INT31547 Binding of Th and Vip 1 0.31 0 1.08
29 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
30 INT41175 Adra2a Regulation of Th 1 0.59 0 1.04
31 INT297487 Negative_regulation of Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.46 1.03
32 INT297486 Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.45 1.02
33 INT31548 Binding of Th and Dbh 1 0.35 0 0.98
34 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
35 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
36 INT60827 Ddc Positive_regulation of Localization of Abat 1 0.12 0.34 0.94
37 INT60828 Ddc Positive_regulation of Abat 1 0.13 0.34 0.93
38 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
39 INT63940 Negative_regulation of Vta1 Positive_regulation of Th 1 0.13 0 0.81
40 INT245350 Abat Regulation of Dbh 1 0.00 0.37 0.8
41 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
42 INT74829 Oprd1 Regulation of Slc1a2 1 0.17 0 0.76
43 INT64067 Tp63 Negative_regulation of Localization of Gh1 1 0.08 0.07 0.76
44 INT69692 Helt Regulation of Prkaca 1 0.00 0.33 0.76
45 INT334348 GRP Regulation of Helt 1 0.01 0 0.72
46 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
47 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
48 INT104110 Negative_regulation of Adrbk2 Negative_regulation of Oprm1 1 0.00 0 0.71
49 INT104102 Negative_regulation of Adrbk2 Negative_regulation of Oprl1 1 0.06 0 0.7
50 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
51 INT64070 Tp63 Regulation of Ghrh 1 0.04 0.06 0.69
52 INT64068 Tp63 Regulation of Fdft1 1 0.00 0.06 0.69
53 INT99937 Ddc Regulation of Transcription of Qrfp 1 0.02 0 0.69
54 INT197233 Positive_regulation of Rora Positive_regulation of Localization of Helt 1 0.00 0 0.68
55 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
56 INT152923 Aanat Positive_regulation of Helt 1 0.00 0.42 0.67
57 INT326586 SLC18A2 Negative_regulation of DDC 1 0.28 0.91 0.66
58 INT28975 Ins1 Positive_regulation of Positive_regulation of Dbh 1 0.21 0 0.66
59 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
60 INT50634 Ddc Regulation of Gene_expression of Glul 1 0.02 0 0.65
61 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
62 INT7958 LOC686180 Positive_regulation of Gene_expression of Th 1 0.02 0 0.64
63 INT127057 Ddc Positive_regulation of Gene_expression of Slc1a2 1 0.01 0.06 0.63
64 INT113146 Ddc Positive_regulation of Gene_expression of Nr4a1 1 0.06 0.1 0.63
65 INT127056 Ddc Positive_regulation of Transcription of Drd3 1 0.10 0.06 0.63
66 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
67 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
68 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
69 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
70 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
71 INT334346 GRP Regulation of Gene_expression of Helt 1 0.03 0 0.55
72 INT281124 Tcf21 Positive_regulation of Binding of Ddc 1 0.04 1.21 0.54
73 INT62597 Binding of Edn1 and Vip 1 0.23 0.79 0.54
74 INT56733 Ddc Positive_regulation of Localization of GLUL 1 0.00 0 0.54
75 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53
76 INT130160 Pomc Regulation of Edn1 1 0.25 0 0.53
77 INT139750 Ubqln1 Regulation of Dbh 1 0.00 0 0.52
78 INT139751 Dbh Regulation of Localization of Prl 1 0.02 0 0.52
79 INT163481 Binding of Bdnf and Positive_regulation of Regulation of Helt 1 0.21 0 0.51
80 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
81 INT163480 Bdnf Positive_regulation of Regulation of Helt 1 0.22 0 0.51
82 INT93740 Ddc Positive_regulation of Tnf 1 0.00 1.45 0.5
83 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49
84 INT94015 Binding of EDN1 and INSRR 1 0.04 0 0.49
85 INT94024 Binding of EDN1 and EDN3 1 0.27 0 0.49
86 INT249000 Helt Negative_regulation of Per2 1 0.01 0 0.48
87 INT168110 Binding of Cnr1 and Dbh 1 0.04 0.64 0.47
88 INT168111 Dbh Positive_regulation of Cnr1 1 0.05 0.64 0.47
89 INT7957 Calca Positive_regulation of Gene_expression of Th 1 0.39 0 0.47
90 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
91 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45
92 INT13247 Binding of Arc and Helt 1 0.00 0.37 0.45
93 INT291387 Cntf Positive_regulation of Slc1a2 1 0.12 0.34 0.45
94 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
95 INT157451 Binding of Slc6a3 and Dbh 1 0.04 0.48 0.44
96 INT250251 Binding of SLC1A2 and SLC1A3 1 0.09 1.12 0.43
97 INT121837 Sct Positive_regulation of Th 1 0.23 0.06 0.43
98 INT313704 Smn1 Negative_regulation of Gene_expression of Edn1 1 0.32 0 0.42
99 INT139487 Oprm1 Positive_regulation of Th 1 0.26 0.1 0.42
100 INT231303 Binding of Prnp and Helt 1 0.02 3.23 0.41
101 INT205926 Helt Regulation of Cpox 1 0.01 0 0.41
102 INT7625 Man2a2 Regulation of Th 1 0.01 0.07 0.4
103 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
104 INT34856 Hpd Negative_regulation of Dbh 1 0.00 0 0.39
105 INT250250 Gene_expression of AQP4 Positive_regulation of Gene_expression of SLC1A2 1 0.37 1.1 0.39
106 INT31794 Hps6 Positive_regulation of Th 1 0.03 0 0.38
107 INT64639 Slc1a1 Positive_regulation of Ddc 1 0.30 0.3 0.38
108 INT50635 Ddc Regulation of Gene_expression of Penk 1 0.03 0 0.38
109 INT173704 Binding of PCOS1 and Edn1 1 0.01 0.99 0.37
110 INT249004 Helt Regulation of Clock 1 0.01 0.09 0.37
111 INT313701 Calca Negative_regulation of Binding of Edn1 1 0.30 0.14 0.37
112 INT249015 Regulation of Helt Regulation of Clock 1 0.01 0.09 0.37
113 INT281155 Binding of ITIH4 and Ddc 1 0.09 1.27 0.37
114 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
115 INT122757 Helt Positive_regulation of Trib3 1 0.00 0.2 0.35
116 INT250252 Binding of SLC1A2 and GOPC 1 0.05 0.44 0.35
117 INT122758 Positive_regulation of Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
118 INT122755 Helt Positive_regulation of Pik3cb 1 0.00 0.19 0.35
119 INT122756 Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
120 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34
121 INT258762 Binding of Dbh and ADHD1 1 0.08 1.61 0.34
122 INT150458 Prss12 Regulation of Helt 1 0.00 0 0.34
123 INT291394 Gene_expression of HTT Negative_regulation of Gene_expression of Slc1a2 1 0.11 0.96 0.34
124 INT173476 Th Regulation of Gene_expression of Bcar1 1 0.10 0 0.34
125 INT34855 Negative_regulation of Maoa Negative_regulation of Th 1 0.17 0 0.34
126 INT163482 Bdnf Regulation of Negative_regulation of Helt 1 0.01 0 0.34
127 INT173478 Th Regulation of Localization of Ins1 1 0.13 0 0.34
128 INT207576 RETN Positive_regulation of Gene_expression of EDN1 1 0.05 0.78 0.33
129 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
130 INT326587 GYPA Regulation of DDC 1 0.08 0.83 0.33
131 INT163483 Bdnf Regulation of Regulation of Helt 1 0.01 0 0.33
132 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32
133 INT153019 nct Positive_regulation of Transcription of Th 1 0.19 0.61 0.32
134 INT153020 nct Positive_regulation of Gene_expression of Th 1 0.19 0.61 0.32
135 INT67266 Edn1 Negative_regulation of Ece1 1 0.19 0.17 0.32
136 INT126097 Ddc Positive_regulation of Egr1 1 0.08 0 0.32
137 INT28688 Binding of Kng1 and Ctsl1 1 0.15 0 0.31
138 INT182262 EDN1 Positive_regulation of Gene_expression of NOS2 1 0.28 0.79 0.31
139 INT1757 DDC Regulation of Localization of GH1 1 0.01 0 0.31
140 INT71519 Edn1 Positive_regulation of Gene_expression of Adarb1 1 0.02 0.48 0.31
141 INT55404 Binding of ENG and Th 1 0.02 0 0.3
142 INT314484 TH Positive_regulation of RLS 1 0.01 1.66 0.29
143 INT83568 Adrbk2 Regulation of Oprk1 1 0.02 0 0.29
144 INT146911 Binding of Helt and Nts 1 0.00 0 0.28
145 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
146 INT42354 Dbh Regulation of Localization of Gh1 1 0.07 0 0.28
147 INT78484 Binding of DBH and TH 1 0.09 0 0.28
148 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
149 INT325767 Negative_regulation of Omd Positive_regulation of Ddc 1 0.01 0.38 0.25
150 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
151 INT178095 EDN1 Positive_regulation of MMP3 1 0.04 0.88 0.24
152 INT178076 EDN1 Positive_regulation of MMP2 1 0.04 0.88 0.24
153 INT178085 EDN1 Positive_regulation of MMP7 1 0.06 0.89 0.24
154 INT178141 EDN1 Positive_regulation of Timp1 1 0.30 0.89 0.24
155 INT178075 EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
156 INT178104 EDN1 Positive_regulation of Localization of TIMP1 1 0.05 0.83 0.24
157 INT178094 Positive_regulation of EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
158 INT178142 EDN1 Positive_regulation of Localization of Timp1 1 0.28 0.89 0.24
159 INT178077 EDN1 Positive_regulation of MMP9 1 0.06 0.88 0.24
160 INT336561 Binding of DDC and DIO2 1 0.04 0.27 0.24
161 INT329432 Binding of CCR6 and TH 1 0.00 0.47 0.23
162 INT105915 Helt Regulation of Gnrh1 1 0.02 0 0.23
163 INT329431 Binding of CCL20 and TH 1 0.00 0.47 0.23
164 INT164 Ddc Negative_regulation of Prl 1 0.06 0 0.23
165 INT182272 EDN1 Regulation of Gene_expression of MMP13 1 0.26 0.87 0.22
166 INT91686 Mb Positive_regulation of Edn1 1 0.03 0.29 0.22
167 INT182265 EDN1 Positive_regulation of NOS2 1 0.24 0.56 0.22
168 INT182263 EDN1 Positive_regulation of MMP1 1 0.15 0.43 0.21
169 INT194100 Binding of MKLN1 and HELT 1 0.01 1.23 0.21
170 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 0.05 0.82 0.2
171 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
172 INT61987 Th Regulation of Penk 1 0.46 0 0.2
173 INT182258 EDN1 Positive_regulation of Positive_regulation of MMP1 1 0.15 0.47 0.19
174 INT182271 EDN1 Positive_regulation of Localization of MMP13 1 0.27 0.47 0.19
175 INT231305 Positive_regulation of Binding of Prnp and Helt 1 0.03 1.63 0.19
176 INT219915 Edn1 Regulation of Positive_regulation of Trpv1 1 0.33 0 0.18
177 INT140096 Gtf3a Positive_regulation of Gene_expression of Edn1 1 0.02 0.44 0.18
178 INT60778 Edn1 Positive_regulation of EDNRA 1 0.00 0 0.18
179 INT342744 Ddc Regulation of Trh 1 0.02 0.37 0.18
180 INT140094 Ifng Regulation of Gene_expression of Edn1 1 0.18 0.44 0.18
181 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
182 INT88450 Uncx Regulation of Gene_expression of Th 1 0.06 0 0.17
183 INT203759 Binding of EDN1 and TNF 1 0.16 0.71 0.16
184 INT94022 Positive_regulation of Binding of EDN1 and INSRR 1 0.06 0 0.16
185 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.91 0.16
186 INT94021 Binding of EDN1 and EDN2 1 0.26 0 0.16
187 INT94014 Positive_regulation of Binding of EDN1 and EDN3 1 0.36 0 0.16
188 INT250246 SLC1A2 Positive_regulation of AQP4 1 0.13 0.22 0.16
189 INT157097 Ddc Positive_regulation of Drd3 1 0.30 0.88 0.16
190 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 0.06 0.51 0.15
191 INT21509 Agt Regulation of Edn1 1 0.53 0 0.15
192 INT182261 EDN1 Regulation of Gene_expression of MMP1 1 0.17 0.7 0.15
193 INT99084 Ddc Positive_regulation of Pdyn 2 0.15 0.87 0.14
194 INT161799 Positive_regulation of Binding of ECE1 and EDN1 1 0.07 0.68 0.14
195 INT268733 Slc1a3 Regulation of Binding of Slc1a2 1 0.39 0.23 0.14
196 INT268735 Slc1a2 Regulation of Binding of Slc1a3 1 0.39 0.23 0.14
197 INT332689 Binding of Edn1 and Ros1 1 0.08 0.71 0.14
198 INT194360 SNRPD1 Negative_regulation of Dbh 1 0.00 0 0.14
199 INT261456 Sftpd Positive_regulation of Gene_expression of Th 1 0.10 0.77 0.13
200 INT161798 Positive_regulation of Binding of EDN1 and ING1 1 0.06 0.66 0.13

Single Events

The table below shows the top 100 pain related interactions that have been reported for multicellular organismal aging. They are ordered first by their pain relevance and then by number of times they were reported in multicellular organismal aging. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
2 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
3 INT7327 Regulation of Th 164 0.62 29.67 110.14
4 INT74826 Gene_expression of Slc1a2 131 0.78 61.83 100.84
5 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
6 INT74827 Positive_regulation of Gene_expression of Slc1a2 52 0.70 26.54 50.63
7 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
8 INT60388 Gene_expression of Helt 90 0.07 19.18 41.72
9 INT350 Localization of Th 79 0.80 10.26 41.17
10 INT7326 Transcription of Th 83 0.72 13.5 35.33
11 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
12 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89
13 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31
14 INT11796 Positive_regulation of Helt 52 0.31 11.7 29.22
15 INT67 Negative_regulation of Ddc 66 0.59 15.34 28.96
16 INT1166 Negative_regulation of Dbh 56 0.59 12.54 28.26
17 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
18 INT4781 Gene_expression of TH 68 0.73 26.92 24.01
19 INT99539 Positive_regulation of Slc1a2 25 0.67 5.46 23.38
20 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78
21 INT3382 Positive_regulation of Dbh 33 0.70 11.64 21.67
22 INT13643 Phosphorylation of Th 20 0.82 1.9 20.97
23 INT93485 Negative_regulation of Slc1a2 27 0.59 10.65 20.9
24 INT6230 Localization of Ddc 40 0.79 13.11 20.88
25 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85
26 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
27 INT5048 Binding of Edn1 55 0.47 18.86 19.16
28 INT2960 Regulation of Dbh 32 0.47 10.32 18.94
29 INT13244 Binding of Helt 30 0.31 4.56 18.01
30 INT96532 Negative_regulation of Gene_expression of Slc1a2 24 0.59 14.22 17.91
31 INT98110 Regulation of Gene_expression of Slc1a2 16 0.62 11.76 17.31
32 INT4073 Localization of Dbh 28 0.81 6.06 16.37
33 INT13716 Positive_regulation of TH 33 0.68 19.11 16
34 INT9191 Localization of EDN1 94 0.81 57.01 14.78
35 INT11795 Negative_regulation of Helt 33 0.28 6.51 14.76
36 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
37 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
38 INT6365 Localization of Edn1 56 0.81 18.84 13.83
39 INT13572 Localization of Helt 31 0.36 5.85 13.41
40 INT31368 Positive_regulation of Positive_regulation of Th 19 0.51 2.2 12.68
41 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
42 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64
43 INT141 Binding of Th 21 0.48 3.53 11.04
44 INT74828 Regulation of Slc1a2 12 0.61 3.92 10.3
45 INT9027 Positive_regulation of Ddc 24 0.66 6.04 10.19
46 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
47 INT48496 Regulation of Transcription of Th 16 0.54 2.29 10.02
48 INT53062 Gene_expression of Ddc 31 0.77 11.59 9.63
49 INT179753 Gene_expression of SLC1A2 28 0.59 13.72 8.71
50 INT33944 Regulation of Helt 13 0.24 2.86 8.49
51 INT10237 Binding of EDN1 40 0.48 16 8.48
52 INT5401 Gene_expression of DBH 17 0.78 1.92 8.01
53 INT47546 Binding of Dbh 11 0.44 5.69 7.84
54 INT26643 Negative_regulation of Positive_regulation of Th 12 0.59 1.26 7.74
55 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
56 INT47811 Positive_regulation of Localization of Ddc 11 0.69 4 7.6
57 INT4284 Regulation of Ddc 17 0.43 8.17 7.31
58 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
59 INT7624 Positive_regulation of Regulation of Th 7 0.50 2.41 7
60 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88
61 INT3506 Localization of TH 12 0.81 0.78 6.66
62 INT7569 Positive_regulation of Transcription of Th 19 0.70 2.6 6.17
63 INT179744 Negative_regulation of SLC1A2 16 0.45 12.32 6.14
64 INT54713 Gene_expression of Adrbk2 12 0.65 0.08 5.92
65 INT30317 Regulation of TH 14 0.43 7.27 5.38
66 INT144735 Gene_expression of DDC 8 0.75 3.21 5.31
67 INT7623 Regulation of Regulation of Th 11 0.44 1.31 5.16
68 INT40620 Regulation of Positive_regulation of Th 9 0.45 2.45 4.69
69 INT124920 Positive_regulation of Negative_regulation of Slc1a2 4 0.58 0.06 4.69
70 INT111055 Localization of Slc1a2 4 0.71 2.04 4.41
71 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
72 INT30165 Positive_regulation of Phosphorylation of Th 8 0.56 0.75 4.22
73 INT77823 Negative_regulation of Negative_regulation of Th 9 0.59 1.56 3.79
74 INT99535 Transcription of Slc1a2 6 0.72 1.31 3.46
75 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
76 INT12844 Binding of TP63 15 0.47 10.57 3.38
77 INT5400 Positive_regulation of DBH 6 0.70 2.02 3.38
78 INT30166 Regulation of Phosphorylation of Th 4 0.50 0.52 3.33
79 INT15253 Binding of DBH 7 0.36 3.21 3.17
80 INT179756 Positive_regulation of Gene_expression of SLC1A2 8 0.38 2.95 3.06
81 INT4782 Positive_regulation of Gene_expression of TH 12 0.47 7.36 2.95
82 INT28376 Regulation of Localization of Dbh 1 0.31 0 2.87
83 INT47812 Negative_regulation of Localization of Ddc 5 0.51 1.99 2.8
84 INT124922 Negative_regulation of Negative_regulation of Slc1a2 2 0.35 0.07 2.79
85 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71
86 INT142525 Binding of Slc1a2 4 0.45 0.94 2.65
87 INT2958 Transcription of Dbh 4 0.71 2.57 2.64
88 INT16406 Positive_regulation of Negative_regulation of Ddc 6 0.67 0.53 2.6
89 INT106066 Negative_regulation of Positive_regulation of TH 1 0.18 0.22 2.6
90 INT106068 Positive_regulation of Positive_regulation of TH 1 0.21 0.22 2.59
91 INT4704 Positive_regulation of Negative_regulation of Th 4 0.50 0.06 2.56
92 INT13644 Negative_regulation of Phosphorylation of Th 2 0.43 0.06 2.51
93 INT167096 Positive_regulation of Gene_expression of Helt 10 0.05 0.89 2.49
94 INT2695 Regulation of DBH 5 0.45 1.09 2.48
95 INT28971 Positive_regulation of Gene_expression of Dbh 4 0.47 0.58 2.39
96 INT15210 Negative_regulation of Transcription of Th 9 0.59 0.47 2.37
97 INT250283 Positive_regulation of SLC1A2 5 0.53 3.22 2.29
98 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
99 INT15209 Negative_regulation of Regulation of Th 6 0.51 1.64 2.16
100 INT179750 Negative_regulation of Gene_expression of SLC1A2 3 0.45 3.05 2.15
101 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07
102 INT205920 Regulation of Gene_expression of Helt 4 0.02 1 2.06
103 INT2961 Regulation of Regulation of Dbh 3 0.24 0.95 2.05
104 INT14360 Positive_regulation of DDC 7 0.70 2.97 2.02
105 INT157095 Binding of Ddc 5 0.27 4.6 2
106 INT243846 Localization of DDC 3 0.63 0.66 1.99
107 INT179749 Regulation of SLC1A2 3 0.34 2.28 1.99
108 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92
109 INT1834 Positive_regulation of Binding of Th 1 0.46 0 1.91
110 INT314510 Protein_catabolism of TH 1 0.10 3.28 1.86
111 INT22087 Negative_regulation of DBH 3 0.59 1.45 1.84
112 INT3505 Binding of TH 5 0.39 2.6 1.8
113 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79
114 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76
115 INT173700 Negative_regulation of Binding of Edn1 2 0.58 0.41 1.76
116 INT99537 Positive_regulation of Transcription of Slc1a2 4 0.70 0.8 1.69
117 INT151271 Positive_regulation of Positive_regulation of Slc1a2 1 0.32 0 1.69
118 INT14842 Negative_regulation of Binding of EDN1 4 0.57 0.67 1.66
119 INT145545 Transcription of TH 3 0.67 1.48 1.64
120 INT113985 Positive_regulation of TP63 9 0.50 8.79 1.62
121 INT193823 Positive_regulation of Gene_expression of TP63 7 0.18 7.74 1.57
122 INT83563 Positive_regulation of Gene_expression of Adrbk2 2 0.58 0 1.57
123 INT54711 Regulation of Adrbk2 1 0.59 0 1.57
124 INT104106 Localization of Adrbk2 3 0.19 0.35 1.53
125 INT181579 Phosphorylation of Edn1 1 0.71 8.59 1.51
126 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48
127 INT4074 Negative_regulation of Localization of Dbh 4 0.59 0.61 1.48
128 INT82676 Negative_regulation of Gene_expression of Ddc 4 0.55 0.55 1.43
129 INT121307 Gene_expression of Ercc1 4 0.73 12.69 1.37
130 INT54712 Positive_regulation of Adrbk2 3 0.66 0.34 1.35
131 INT333291 Positive_regulation of Gene_expression of DDC 1 0.49 0.13 1.35
132 INT141233 Negative_regulation of Positive_regulation of Dbh 2 0.42 0.39 1.33
133 INT121136 Negative_regulation of DDC 4 0.57 2.98 1.32
134 INT179754 Regulation of Gene_expression of SLC1A2 3 0.34 0.93 1.32
135 INT13573 Negative_regulation of Localization of Helt 3 0.00 0.86 1.26
136 INT38650 Positive_regulation of Negative_regulation of Dbh 3 0.50 0 1.16
137 INT26760 Negative_regulation of Localization of Th 2 0.40 0.09 1.14
138 INT278117 Negative_regulation of TP63 5 0.32 3.38 1.13
139 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12
140 INT89670 Negative_regulation of Binding of Th 2 0.43 0.28 1.12
141 INT116213 Regulation of Transcription of Slc1a2 1 0.61 0.41 1.12
142 INT23716 Localization of DBH 1 0.29 0.06 1.11
143 INT28972 Regulation of Gene_expression of Dbh 2 0.42 0.86 1.08
144 INT83566 Negative_regulation of Adrbk2 2 0.23 0 1.03
145 INT50812 Regulation of Positive_regulation of Dbh 2 0.45 1.04 1
146 INT69803 Regulation of Localization of Edn1 3 0.62 0.79 0.98
147 INT49255 Protein_catabolism of EDN1 5 0.99 2.66 0.95
148 INT69422 Positive_regulation of Negative_regulation of EDN1 2 0.43 0.96 0.95
149 INT208792 Negative_regulation of Gene_expression of TH 6 0.35 1.11 0.94
150 INT49254 Transcription of EDN1 5 0.69 2.42 0.94
151 INT6534 Negative_regulation of Ctsl1 3 0.54 0.11 0.94
152 INT30598 Negative_regulation of Transcription of Dbh 1 0.42 0.35 0.91
153 INT11072 Binding of HELT 4 0.31 3.81 0.89
154 INT208789 Negative_regulation of Localization of TH 2 0.25 0 0.89
155 INT61591 Negative_regulation of Localization of EDN1 11 0.59 2.09 0.85
156 INT53309 Regulation of Localization of Th 1 0.39 0 0.84
157 INT57433 Positive_regulation of Binding of EDN1 3 0.49 0.62 0.82
158 INT86036 Negative_regulation of Positive_regulation of Ddc 2 0.35 0.42 0.8
159 INT352657 Transcription of SLC1A2 1 0.06 0.76 0.8
160 INT28974 Negative_regulation of Negative_regulation of Dbh 1 0.40 0 0.78
161 INT44293 Regulation of TP63 6 0.24 2.88 0.76
162 INT61121 Regulation of Regulation of Edn1 1 0.43 0.2 0.75
163 INT2959 Regulation of Transcription of Dbh 2 0.45 1.18 0.73
164 INT87728 Regulation of Gene_expression of Ddc 4 0.25 1.1 0.71
165 INT59970 Positive_regulation of Binding of Edn1 2 0.40 1.11 0.71
166 INT30807 Negative_regulation of Positive_regulation of Helt 1 0.00 0.08 0.7
167 INT21957 Negative_regulation of Negative_regulation of Edn1 5 0.43 1.34 0.69
168 INT104103 Positive_regulation of Localization of Adrbk2 1 0.08 0 0.69
169 INT231290 Positive_regulation of Positive_regulation of Helt 3 0.03 1.71 0.68
170 INT4072 Positive_regulation of Positive_regulation of Dbh 3 0.50 1.77 0.67
171 INT49252 Positive_regulation of Localization of EDN1 17 0.69 6.55 0.66
172 INT100396 Transcription of Edn1 7 0.69 2.48 0.66
173 INT258710 Regulation of Negative_regulation of Ddc 2 0.25 1.28 0.66
174 INT49256 Regulation of Positive_regulation of EDN1 2 0.45 2.5 0.65
175 INT268729 Negative_regulation of Positive_regulation of Slc1a2 2 0.40 0.89 0.63
176 INT122934 Negative_regulation of Regulation of TH 1 0.03 0.56 0.63
177 INT131135 Regulation of Regulation of Helt 1 0.03 0 0.63
178 INT13929 Protein_catabolism of Th 3 1.00 0 0.58
179 INT232442 Negative_regulation of Gene_expression of DDC 1 0.05 1.44 0.58
180 INT28687 Gene_expression of Ctsl1 4 0.61 0.48 0.57
181 INT7153 Positive_regulation of Regulation of Edn1 2 0.35 1.97 0.57
182 INT135715 Negative_regulation of Localization of Edn1 5 0.42 1.7 0.56
183 INT314505 Positive_regulation of Protein_catabolism of TH 1 0.05 1.07 0.56
184 INT117782 Negative_regulation of Negative_regulation of Helt 1 0.28 0.07 0.55
185 INT51843 Localization of Ctsl1 3 0.62 0.54 0.54
186 INT314499 Negative_regulation of Protein_catabolism of TH 1 0.04 1.06 0.54
187 INT181581 Regulation of Positive_regulation of Edn1 4 0.23 3.76 0.51
188 INT71274 Gene_expression of Acan 3 0.12 0.99 0.5
189 INT306741 Positive_regulation of Positive_regulation of TP63 2 0.05 1.16 0.49
190 INT144737 Regulation of Gene_expression of DDC 1 0.06 0 0.49
191 INT278121 Negative_regulation of Negative_regulation of TP63 1 0.03 0 0.48
192 INT3381 Positive_regulation of Regulation of Dbh 2 0.44 0.37 0.47
193 INT6533 Binding of Ctsl1 2 0.34 0 0.45
194 INT111304 Regulation of Gene_expression of TH 2 0.17 0.57 0.44
195 INT133179 Transcription of DBH 1 0.70 0.23 0.44
196 INT250276 Localization of SLC1A2 1 0.61 2.4 0.44
197 INT57434 Regulation of Regulation of EDN1 1 0.40 0.47 0.44
198 INT352656 Positive_regulation of Transcription of SLC1A2 1 0.04 0.39 0.43
199 INT121310 Positive_regulation of Ercc1 2 0.45 1.78 0.42
200 INT258772 Regulation of DDC 1 0.36 0.05 0.4
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox