GO:0010288

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Name response to lead ion
Categary Process
Go Slim No
Go Link GO:0010288
Unique Molecular Interactions 391
Total Molecular Interactions 598
Total Single Events 10100
Pain Genes Associated 26

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to lead ion. They are ordered first by their pain relevance and then by number of times they were reported for response to lead ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54
2 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37
3 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
4 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
5 INT103592 CAP1 Negative_regulation of Gene_expression of CPOX 1 0.19 1.52 1.64
6 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
7 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
8 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
9 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
10 INT190128 Positive_regulation of PTGER1 Negative_regulation of Gene_expression of CPOX 1 0.04 1.21 1.38
11 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
12 INT2641 Binding of Pomc and Lct 2 0.31 0.57 1.32
13 INT124925 Negative_regulation of Slc6a1 Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
14 INT195541 Lct Positive_regulation of Gene_expression of Grm2 1 0.02 0.4 1.27
15 INT190130 Binding of CPOX and MRXS5 1 0.00 1.4 1.23
16 INT224410 Binding of CRP and CIMT 3 0.42 10.46 1.2
17 INT107029 Cpox Regulation of Pag1 1 0.01 1.24 1.15
18 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
19 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
20 INT150787 ZNF398 Positive_regulation of Gene_expression of SPARC 1 0.13 1.02 1.05
21 INT323077 CPOX Negative_regulation of Gene_expression of Ptger2 1 0.00 1.57 1.05
22 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
23 INT119914 Olr1714 Negative_regulation of Nos1 1 0.02 0.47 1.01
24 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
25 INT147506 Binding of Ncam1 and Gtf3a 1 0.03 0.88 0.99
26 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98
27 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
28 INT303690 KNG1 Positive_regulation of CPOX 1 0.01 0.76 0.96
29 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
30 INT134782 Il2rb Regulation of Gene_expression of Crp 1 0.00 1.16 0.92
31 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89
32 INT75920 Slc8a1 Negative_regulation of Cpox 1 0.03 0.85 0.89
33 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
34 INT107698 FN1 Positive_regulation of Gene_expression of CPOX 1 0.13 0.26 0.84
35 INT149925 Negative_regulation of Cpox Negative_regulation of Gene_expression of Pde4d 1 0.01 0.39 0.84
36 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83
37 INT102931 Nos3 Positive_regulation of Nos2 1 0.43 1.63 0.83
38 INT84717 Il1b Regulation of Cpox 1 0.00 0.37 0.83
39 INT155761 Binding of Nos1 and Tjp1 1 0.13 1.01 0.82
40 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
41 INT102932 Nos3 Positive_regulation of NOS1 1 0.03 1.63 0.82
42 INT155760 Binding of Nos1 and Dlg4 1 0.13 1.01 0.82
43 INT84039 EGF Positive_regulation of Gene_expression of CPOX 2 0.11 1.88 0.8
44 INT84040 EGF Positive_regulation of CPOX 2 0.07 1.91 0.8
45 INT140966 NFKB1 Positive_regulation of Positive_regulation of CPOX 1 0.08 0.66 0.8
46 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
47 INT16507 Binding of LPA and Crp 1 0.00 0.78 0.78
48 INT16488 Binding of Serpinf2 and Crp 1 0.00 0.78 0.78
49 INT16506 Positive_regulation of Binding of LPA and Crp 1 0.00 0.78 0.78
50 INT16489 Positive_regulation of Binding of Serpinf2 and Crp 1 0.00 0.78 0.78
51 INT322201 Binding of OAP and SLC34A1 1 0.01 1.49 0.77
52 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
53 INT141911 Arih2 Regulation of Positive_regulation of Cpox 1 0.01 1.19 0.76
54 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
55 INT90125 Nfkb1 Regulation of Gene_expression of Nos1 1 0.17 0.39 0.76
56 INT141910 Arih2 Regulation of Cpox 1 0.01 1.19 0.76
57 INT90116 Nfkb1 Positive_regulation of Gene_expression of Nos1 1 0.32 0.39 0.76
58 INT107702 DCSTAMP Positive_regulation of Gene_expression of CPOX 1 0.04 0.32 0.75
59 INT108611 Adra2a Regulation of Gene_expression of Nos1 1 0.10 0 0.75
60 INT119313 Cpox Regulation of Gene_expression of Ptger2 1 0.02 0.6 0.74
61 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
62 INT117639 Serpini1 Negative_regulation of Cpox 1 0.00 0.64 0.72
63 INT240729 Binding of CRP and HLA-A 1 0.11 2.18 0.71
64 INT106154 Calca Positive_regulation of Nos1 1 0.29 0.2 0.68
65 INT202037 Binding of CRP and URB1 1 0.01 1.26 0.68
66 INT347962 Cpox Negative_regulation of Positive_regulation of Nos1 1 0.02 0.59 0.67
67 INT220032 Nos1 Positive_regulation of Nos3 1 0.32 0.45 0.66
68 INT220035 Nos1 Positive_regulation of Nos2 1 0.29 0.45 0.66
69 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 2 0.03 0.24 0.65
70 INT78663 Dlst Regulation of Nos1 1 0.19 0.91 0.65
71 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65
72 INT92045 Binding of ALB and SERPINA1 1 0.30 1.37 0.64
73 INT177899 Crp Positive_regulation of Positive_regulation of Crp 1 0.01 1.69 0.6
74 INT105848 Il1b Positive_regulation of Gene_expression of Cpox 1 0.12 0.41 0.59
75 INT59201 ecs Positive_regulation of Ncam1 1 0.01 0.98 0.59
76 INT327165 RETNLB Regulation of Gene_expression of CRP 1 0.01 2.25 0.59
77 INT316674 Binding of CRP and SFTPD 1 0.16 2.02 0.59
78 INT270099 Negative_regulation of Binding of CPOX and PLA2G2A 1 0.01 0.51 0.59
79 INT175700 Nos3 Negative_regulation of smc 1 0.01 1.05 0.59
80 INT157141 Cpox Positive_regulation of Gene_expression of Camk2a 1 0.19 0.13 0.58
81 INT270103 Binding of CPOX and PLA2G2A 1 0.01 0.5 0.58
82 INT145491 PROC Positive_regulation of Cpox 1 0.00 1.08 0.58
83 INT223924 Cux1 Regulation of Gene_expression of Serpina1 1 0.04 0.15 0.57
84 INT122313 Nfkb1 Regulation of Gene_expression of Cpox 1 0.00 0.51 0.57
85 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56
86 INT122314 Nfkb1 Regulation of Cpox 1 0.00 0.51 0.56
87 INT270101 CPOX Negative_regulation of PLA2G2A 1 0.01 0.48 0.56
88 INT122315 Negative_regulation of Nfkb1 Regulation of Cpox 1 0.00 0.51 0.56
89 INT147040 Hmbs Negative_regulation of Nppa 1 0.07 0.95 0.55
90 INT278228 Binding of MBNL1 and NOS3 1 0.05 2.06 0.54
91 INT150800 THBS3 Negative_regulation of SPARC 1 0.23 0.51 0.53
92 INT97425 Prkcg Regulation of Regulation of Nos1 1 0.06 0 0.53
93 INT112659 Cpox Positive_regulation of Gene_expression of TNF 1 0.01 0.79 0.52
94 INT112661 Cpox Positive_regulation of Localization of TNF 1 0.01 0.79 0.52
95 INT106744 Binding of CRP and EGFL7 2 0.07 2.35 0.51
96 INT223925 Drd1a Positive_regulation of Gene_expression of Serpina1 1 0.01 0 0.51
97 INT184405 CRP Positive_regulation of Gene_expression of ASF1A 1 0.03 1.17 0.49
98 INT145435 Binding of CPOX and HMOX1 1 0.01 0.42 0.49
99 INT145433 Binding of CPOX and HMOX2 1 0.01 0.42 0.49
100 INT90121 Nos1 Regulation of Fos 1 0.27 0.25 0.49
101 INT351771 Il6 Positive_regulation of Localization of Crp 1 0.01 0.94 0.48
102 INT277063 CRP Positive_regulation of Gene_expression of MMP10 1 0.39 1.53 0.48
103 INT114754 Il6 Positive_regulation of Gene_expression of Crp 2 0.08 1.67 0.47
104 INT277065 CRP Positive_regulation of Gene_expression of MMP1 1 0.41 1.52 0.47
105 INT43646 Negative_regulation of Binding of Pomc and Lct 1 0.38 0 0.47
106 INT203177 Negative_regulation of CPOX Positive_regulation of Gene_expression of Lts1 1 0.00 0.72 0.46
107 INT103025 Calca Positive_regulation of Nos3 1 0.25 0.41 0.46
108 INT103027 Ptgis Positive_regulation of Nos3 1 0.06 0.42 0.46
109 INT95276 Obfc2a Negative_regulation of Nos3 1 0.02 1.02 0.46
110 INT103030 Calca Positive_regulation of Positive_regulation of Nos3 1 0.26 0.41 0.46
111 INT277064 CRP Positive_regulation of Gene_expression of TIMP1 1 0.15 1.47 0.45
112 INT116926 Cpox Regulation of AKR1C3 1 0.01 0.28 0.45
113 INT1311 Lct Positive_regulation of Localization of Gnrhr 1 0.03 0 0.45
114 INT314263 Binding of CPOX and PTGES3 1 0.01 1.7 0.44
115 INT323702 HGF Regulation of Gene_expression of CRP 1 0.01 0.81 0.43
116 INT299041 SPARC Regulation of Gene_expression of NPEPPS 1 0.01 0.83 0.42
117 INT226070 Binding of CRP and MMP9 1 0.51 1.13 0.42
118 INT107701 Negative_regulation of FN1 Positive_regulation of CPOX 1 0.11 0.13 0.42
119 INT299040 Binding of COL7A1 and SPARC 1 0.02 0.7 0.42
120 INT107696 FN1 Positive_regulation of CPOX 1 0.12 0.13 0.41
121 INT107703 PPARG Regulation of Gene_expression of CPOX 1 0.16 0.15 0.41
122 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41
123 INT146273 Binding of Nos1 and Rasd1 1 0.34 0.18 0.41
124 INT326303 Binding of CRP and FKBP4 1 0.15 1.22 0.41
125 INT279414 Binding of CPOX and ACTR1B 1 0.04 1.55 0.4
126 INT58481 Crp Regulation of TF 1 0.01 0.46 0.4
127 INT107706 PPARA Positive_regulation of Gene_expression of CPOX 1 0.18 0.14 0.4
128 INT139047 Negative_regulation of AR Negative_regulation of Positive_regulation of CPOX 1 0.07 0.76 0.4
129 INT146272 Binding of Nos1 and Nos1ap 1 0.28 0.2 0.39
130 INT107700 Positive_regulation of DCSTAMP Positive_regulation of CPOX 1 0.04 0.14 0.38
131 INT107697 DCSTAMP Positive_regulation of CPOX 1 0.06 0.14 0.38
132 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37
133 INT320591 Ca2 Positive_regulation of Nos1 1 0.07 0.09 0.37
134 INT242025 Binding of CRP and CHDH 7 0.18 15.72 0.36
135 INT106511 Binding of Cpox and Ptges3 2 0.01 0.7 0.36
136 INT270789 CRP Negative_regulation of Gene_expression of TNF 1 0.34 0.87 0.36
137 INT278226 Binding of FOSB and NOS3 1 0.03 1.22 0.36
138 INT114755 Il6 Positive_regulation of Crp 1 0.08 0.41 0.35
139 INT90388 NFKB1 Positive_regulation of CPOX 1 0.32 0.18 0.35
140 INT134303 Cpox Negative_regulation of PTGS2 1 0.00 0.77 0.34
141 INT134301 Cpox Negative_regulation of Gene_expression of Ptger2 1 0.00 0.77 0.34
142 INT141848 Mthfs Negative_regulation of Cpox 1 0.01 0 0.34
143 INT203166 Negative_regulation of CPOX Positive_regulation of Gene_expression of LTB4R 1 0.00 0.65 0.34
144 INT240434 PPARA Negative_regulation of Gene_expression of CPOX 1 0.03 0.64 0.33
145 INT99597 Negative_regulation of CPOX Regulation of Negative_regulation of ZNF398 1 0.02 0.44 0.33
146 INT124475 MAP2K1 Positive_regulation of Positive_regulation of CPOX 1 0.04 0.68 0.33
147 INT240129 Binding of Nppb and Crp 1 0.21 1.02 0.32
148 INT277011 CRP Positive_regulation of Gene_expression of F3 1 0.06 1.03 0.32
149 INT78664 Negative_regulation of Nos1 Negative_regulation of Cebpz 1 0.30 0.43 0.32
150 INT194733 Binding of CPOX and HNRNPA0 1 0.01 0.44 0.32
151 INT238895 Binding of CRP and INS 1 0.00 0.93 0.32
152 INT187523 IRF6 Positive_regulation of Gene_expression of Cpox 1 0.00 1.38 0.31
153 INT147041 Hmbs Negative_regulation of Negative_regulation of Nppa 1 0.05 0.51 0.3
154 INT304497 Mknk1 Positive_regulation of Nos1 1 0.19 0.53 0.3
155 INT304504 Mapk1 Positive_regulation of Nos1 1 0.29 0.93 0.3
156 INT74940 HGF Positive_regulation of CPOX 1 0.13 0.25 0.3
157 INT203169 CPOX Regulation of Gene_expression of PTGER2 2 0.00 0.48 0.29
158 INT93580 Hgf Positive_regulation of Cpox 1 0.19 2.2 0.29
159 INT203170 Negative_regulation of CPOX Positive_regulation of ALOX5 1 0.01 0.53 0.29
160 INT141871 Binding of Nos3 and Slc2a4 1 0.25 0.51 0.28
161 INT116592 CPOX Regulation of PTGER2 1 0.02 0.45 0.28
162 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
163 INT116593 CPOX Regulation of IL6 1 0.10 0.45 0.28
164 INT194045 Binding of CRP and PM20D2 1 0.01 1.64 0.27
165 INT280181 Pde5a Positive_regulation of Regulation of Cpox 1 0.00 0.16 0.26
166 INT346196 AMELX Negative_regulation of CRP 1 0.04 0.36 0.26
167 INT242763 Olr1746 Negative_regulation of Nos1 1 0.02 0.97 0.26
168 INT300779 STAT3 Positive_regulation of CRP 1 0.41 0.62 0.26
169 INT300778 STAT3 Positive_regulation of Transcription of CRP 1 0.38 0.62 0.26
170 INT102621 IL6 Regulation of Gene_expression of CPOX 1 0.13 0.78 0.25
171 INT278967 MST1 Regulation of Gene_expression of CPOX 1 0.00 0.41 0.25
172 INT278945 NOS2 Regulation of Gene_expression of CPOX 1 0.02 0.41 0.25
173 INT126227 Hsp90aa1 Positive_regulation of Nos1 1 0.03 0.73 0.25
174 INT226073 Binding of CRP and SHBG 2 0.10 2.14 0.24
175 INT195544 Lct Positive_regulation of Transcription of Grm2 1 0.01 0.06 0.24
176 INT124078 Binding of Ace and Cpox 1 0.09 0.14 0.24
177 INT184404 CRP Regulation of Gene_expression of KRT20 1 0.02 1.21 0.24
178 INT267623 IL6 Positive_regulation of Crp 1 0.00 1.6 0.24
179 INT195547 Lct Positive_regulation of Transcription of Grm3 1 0.00 0.06 0.24
180 INT110061 Binding of Alox5 and Cpox 1 0.28 0.37 0.23
181 INT195553 Lct Positive_regulation of Grm2 1 0.02 0.05 0.23
182 INT139045 Negative_regulation of AR Negative_regulation of CPOX 1 0.07 0.34 0.23
183 INT194047 Negative_regulation of Binding of CRP and PM20D2 1 0.02 1.57 0.23
184 INT195548 Lct Positive_regulation of Grm3 1 0.00 0.06 0.23
185 INT143629 CPOX Positive_regulation of Gene_expression of MRXS5 1 0.05 0.55 0.23
186 INT177895 Binding of Crp and Wbc1 1 0.00 0.45 0.22
187 INT281901 Binding of KNG1 and NOS3 1 0.05 0.17 0.22
188 INT142446 Regulation of CPOX Regulation of Gene_expression of PTGIS 1 0.10 0.26 0.22
189 INT182816 EEF1A2 Negative_regulation of CRP 1 0.28 1.84 0.21
190 INT97472 CPOX Regulation of Gene_expression of MRXS5 1 0.02 0.16 0.21
191 INT228703 MPO Regulation of Positive_regulation of CRP 1 0.40 1.63 0.2
192 INT145140 Negative_regulation of CPOX Negative_regulation of Gene_expression of CYP19A1 1 0.13 0.47 0.2
193 INT264298 NOL3 Negative_regulation of CRP 1 0.39 0.49 0.2
194 INT242037 Binding of CRP and SNRNP70 3 0.07 4.62 0.19
195 INT240625 Binding of CRP and Hdlcl1 1 0.01 2.56 0.19
196 INT175908 Binding of NOS3 and ROS1 1 0.10 1.84 0.19
197 INT137417 MAPK7 Regulation of Gene_expression of NOS3 1 0.00 0.5 0.19
198 INT139302 Binding of CRP and TLR4 1 0.38 1.18 0.19
199 INT139877 CPOX Regulation of Gene_expression of PTGES 1 0.17 0.07 0.18
200 INT139881 CPOX Regulation of Transcription of PTGES 1 0.17 0.07 0.18

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to lead ion. They are ordered first by their pain relevance and then by number of times they were reported in response to lead ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29
2 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19
3 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02
4 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81
5 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03
6 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74
7 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
8 INT55944 Positive_regulation of Cpox 214 0.57 105.14 81.4
9 INT50672 Positive_regulation of CPOX 205 0.44 125.93 60.06
10 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35
11 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
12 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
13 INT35975 Regulation of Cpox 109 0.39 57.88 49.69
14 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33
15 INT50673 Positive_regulation of Gene_expression of CPOX 156 0.54 97.31 37.03
16 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
17 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07
18 INT64171 Regulation of CPOX 109 0.36 55.36 32.96
19 INT100861 Binding of CRP 179 0.48 175.2 26.45
20 INT53949 Positive_regulation of Gene_expression of Cpox 82 0.65 38.12 25.93
21 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9
22 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
23 INT64175 Negative_regulation of Gene_expression of CPOX 66 0.38 39.64 23.07
24 INT23257 Regulation of CRP 127 0.62 100.05 21.87
25 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
26 INT81194 Binding of CPOX 40 0.29 23.7 18.95
27 INT18672 Gene_expression of Ncam1 54 0.78 36.64 18.79
28 INT55335 Binding of Cpox 49 0.34 15.48 18.46
29 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71
30 INT73599 Negative_regulation of Gene_expression of Cpox 47 0.55 19.89 17.26
31 INT106745 Localization of CRP 65 0.81 66.44 15.21
32 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82
33 INT75918 Negative_regulation of Negative_regulation of Cpox 19 0.23 10.05 14.4
34 INT53948 Regulation of Gene_expression of Cpox 40 0.51 20.97 13.87
35 INT50671 Regulation of Gene_expression of CPOX 45 0.54 30.99 13.83
36 INT2336 Negative_regulation of Lct 51 0.58 33.79 13.73
37 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99
38 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
39 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89
40 INT37390 Regulation of Crp 39 0.46 28.74 11.45
41 INT74272 Localization of CPOX 39 0.63 25.12 10.53
42 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52
43 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
44 INT72759 Transcription of Cpox 40 0.39 17.26 10
45 INT76426 Positive_regulation of Negative_regulation of Cpox 18 0.35 6.84 9.95
46 INT74812 Negative_regulation of Positive_regulation of Cpox 17 0.34 10.1 9.94
47 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93
48 INT95271 Negative_regulation of Nos3 46 0.53 24.1 9.71
49 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7
50 INT51922 Localization of Cpox 24 0.68 12.05 8.59
51 INT4159 Gene_expression of Hp 33 0.72 12.49 8.39
52 INT84672 Negative_regulation of Positive_regulation of Nos1 12 0.48 3.76 8.27
53 INT3401 Positive_regulation of Hp 22 0.69 16.33 7.97
54 INT95317 Positive_regulation of Slc6a1 6 0.69 5.91 7.94
55 INT76427 Regulation of Negative_regulation of Cpox 17 0.31 6.75 7.93
56 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92
57 INT17996 Binding of Crp 40 0.37 31.4 7.8
58 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58
59 INT105528 Negative_regulation of Slc6a1 7 0.57 2.79 7.32
60 INT83529 Positive_regulation of Positive_regulation of Cpox 8 0.29 7.22 6.7
61 INT83712 Transcription of Nos3 19 0.69 13.09 6.31
62 INT69499 Binding of Nos1 15 0.36 2.56 6.23
63 INT93658 Transcription of Nos1 16 0.72 6.85 6.16
64 INT77427 Regulation of Negative_regulation of CPOX 17 0.26 10.03 6.15
65 INT95313 Gene_expression of Slc6a1 6 0.76 3.96 6.14
66 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09
67 INT29821 Gene_expression of Serpina1 18 0.60 2.98 5.75
68 INT84673 Localization of Nos1 19 0.80 5.01 5.62
69 INT135319 Positive_regulation of Positive_regulation of CRP 20 0.50 26.45 5.61
70 INT64176 Transcription of CPOX 35 0.41 15.1 5.5
71 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97
72 INT72758 Positive_regulation of Transcription of Cpox 15 0.34 5.46 4.75
73 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68
74 INT69966 Positive_regulation of Negative_regulation of CPOX 11 0.45 6.18 4.64
75 INT77429 Negative_regulation of Negative_regulation of CPOX 9 0.34 5.09 4.64
76 INT133905 Gene_expression of Ncam1 24 0.78 10.2 4.62
77 INT137691 Positive_regulation of Gene_expression of Ncam1 9 0.68 2.3 4.24
78 INT56027 Positive_regulation of Ncam1 12 0.69 4.96 4.1
79 INT104221 Regulation of Gene_expression of CRP 30 0.45 20.01 4.07
80 INT69967 Negative_regulation of Positive_regulation of CPOX 11 0.35 7.73 4.07
81 INT83991 Regulation of Nos3 25 0.44 9.89 4.06
82 INT88651 Phosphorylation of Cpox 5 0.41 2.92 4.04
83 INT102515 Binding of Nos3 19 0.45 9.41 4.01
84 INT51312 Positive_regulation of Gene_expression of SERPINA1 4 0.46 9.41 3.84
85 INT137688 Regulation of Gene_expression of Ncam1 1 0.60 1.21 3.65
86 INT134875 Phosphorylation of Nos1 5 0.70 1.21 3.44
87 INT74022 Regulation of Positive_regulation of Cpox 6 0.24 5.73 3.41
88 INT8539 Negative_regulation of Serpina1a 21 0.58 12.65 3.39
89 INT70958 Binding of NOS3 19 0.37 11.84 3.29
90 INT32353 Regulation of Lct 7 0.52 1.37 3.16
91 INT92814 Negative_regulation of NOS3 25 0.51 20.67 3.07
92 INT62568 Positive_regulation of Positive_regulation of Crp 9 0.68 8.61 2.98
93 INT21299 Negative_regulation of Hp 14 0.44 10.97 2.97
94 INT15288 Regulation of Hp 11 0.60 3.68 2.89
95 INT91869 Transcription of NOS3 13 0.67 6.81 2.86
96 INT114753 Negative_regulation of Gene_expression of Crp 7 0.42 4.79 2.77
97 INT26996 Positive_regulation of Gene_expression of Crp 21 0.68 21.55 2.75
98 INT101883 Regulation of Gene_expression of Nos3 11 0.52 6.71 2.73
99 INT204124 Transcription of CRP 14 0.69 20.79 2.71
100 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71
101 INT90675 Negative_regulation of Gene_expression of Nos3 15 0.46 11.11 2.7
102 INT29818 Regulation of Serpina1 8 0.27 0.08 2.64
103 INT32983 Localization of Lct 8 0.47 0.42 2.6
104 INT108608 Positive_regulation of Positive_regulation of Nos1 8 0.49 1.66 2.58
105 INT153960 Negative_regulation of Gene_expression of Slc6a1 1 0.42 2.4 2.54
106 INT100427 Binding of SERPINA1 9 0.36 9.63 2.51
107 INT10044 Positive_regulation of Serpina1 5 0.69 0.99 2.45
108 INT10048 Positive_regulation of SERPINA1 11 0.68 8.59 2.43
109 INT325972 Negative_regulation of Binding of Slc6a1 1 0.02 0.52 2.38
110 INT325975 Binding of Slc6a1 1 0.02 0.52 2.37
111 INT35359 Negative_regulation of LCT 23 0.59 9.13 2.29
112 INT137690 Negative_regulation of Gene_expression of Ncam1 3 0.50 3.37 2.18
113 INT3784 Regulation of Hmbs 4 0.38 2.79 2.11
114 INT130199 Negative_regulation of Binding of CPOX 4 0.30 1.89 2.1
115 INT82166 Regulation of NOS3 14 0.54 7.57 2.08
116 INT10045 Negative_regulation of Serpina1 7 0.43 1.01 2.07
117 INT83911 Negative_regulation of Gene_expression of SERPINA1 3 0.43 5.2 2.07
118 INT101645 Regulation of Gene_expression of Bcl2l1 8 0.36 5.27 2.05
119 INT91594 Localization of NOS3 12 0.78 5.39 2.02
120 INT67033 Localization of Crp 14 0.54 10.35 2.01
121 INT133906 Positive_regulation of Gene_expression of Ncam1 6 0.70 1.9 2
122 INT66929 Positive_regulation of Localization of Cpox 6 0.25 4.68 1.98
123 INT101166 Negative_regulation of Binding of Cpox 4 0.15 2.66 1.79
124 INT56028 Regulation of Ncam1 6 0.38 3.6 1.78
125 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
126 INT120466 Gene_expression of LCT 21 0.78 6 1.75
127 INT60999 Localization of Nos3 12 0.74 5.28 1.75
128 INT113378 Negative_regulation of Slc34a1 1 0.00 0 1.75
129 INT22591 Negative_regulation of Hmbs 6 0.51 5.04 1.74
130 INT107923 Regulation of Gene_expression of NOS3 11 0.61 2.73 1.73
131 INT64559 Positive_regulation of Negative_regulation of Nos1 2 0.41 1.58 1.68
132 INT97418 Regulation of Regulation of Nos1 2 0.41 0.94 1.68
133 INT223923 Positive_regulation of Gene_expression of Serpina1 1 0.08 0.27 1.67
134 INT28915 Binding of Lct 6 0.17 1.89 1.64
135 INT1462 Positive_regulation of Lct 7 0.49 1.5 1.61
136 INT97318 Gene_expression of SPARC 11 0.67 5.07 1.59
137 INT133904 Positive_regulation of Ncam1 7 0.50 4.01 1.57
138 INT75230 Transcription of Crp 4 0.55 3.15 1.57
139 INT223920 Regulation of Gene_expression of Serpina1 1 0.05 0.4 1.57
140 INT72760 Regulation of Transcription of Cpox 6 0.24 1.84 1.54
141 INT106413 Transcription of Bcl2l1 8 0.53 3.35 1.52
142 INT68766 Positive_regulation of Transcription of CPOX 10 0.30 4.76 1.49
143 INT102711 Regulation of Gene_expression of Crp 3 0.44 1.63 1.47
144 INT181639 Positive_regulation of Positive_regulation of NOS3 8 0.41 3.72 1.41
145 INT83713 Positive_regulation of Transcription of Nos3 3 0.67 2.92 1.38
146 INT42530 Gene_expression of Lct 11 0.66 9.37 1.37
147 INT89785 Regulation of Transcription of Nos3 1 0.32 0.85 1.36
148 INT91863 Negative_regulation of Gene_expression of NOS3 13 0.51 9.43 1.34
149 INT122345 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0 1.34
150 INT105881 Phosphorylation of Bcl2l1 3 0.51 1.99 1.31
151 INT115938 Negative_regulation of Negative_regulation of Nos1 2 0.36 0.27 1.31
152 INT136612 Positive_regulation of Positive_regulation of Nos3 5 0.43 4.22 1.26
153 INT93702 Localization of Hmbs 1 0.81 4.84 1.26
154 INT171576 Phosphorylation of CRP 6 0.80 5.55 1.22
155 INT84714 Negative_regulation of Transcription of Cpox 3 0.25 1.5 1.18
156 INT11109 Positive_regulation of Serpina1a 5 0.68 4.97 1.12
157 INT95312 Regulation of Slc6a1 3 0.27 0.77 1.09
158 INT59010 Positive_regulation of Regulation of Crp 2 0.27 2.11 1.09
159 INT159477 Phosphorylation of NOS3 14 0.72 1.54 1.08
160 INT147712 Regulation of Negative_regulation of Slc6a1 1 0.45 0 1.07
161 INT78354 Positive_regulation of Positive_regulation of CPOX 8 0.19 2.82 1.06
162 INT108609 Regulation of Localization of Nos1 3 0.45 0 1.06
163 INT154842 Positive_regulation of Phosphorylation of Cpox 1 0.13 0.07 1.05
164 INT107922 Positive_regulation of Gene_expression of NOS3 17 0.60 9.32 1.04
165 INT168784 Regulation of Positive_regulation of Slc6a1 1 0.45 0.87 1.01
166 INT164863 Positive_regulation of Phosphorylation of Bcl2l1 1 0.31 0.57 1.01
167 INT3402 Positive_regulation of Positive_regulation of Hp 2 0.49 1.05 1
168 INT115987 Positive_regulation of SPARC 4 0.44 1.52 0.99
169 INT165835 Positive_regulation of Lct 3 0.49 1.03 0.99
170 INT122347 Transcription of Hsd3b1 1 0.52 0 0.99
171 INT201393 Positive_regulation of Regulation of CPOX 1 0.09 1.51 0.98
172 INT106941 Positive_regulation of Negative_regulation of Slc6a1 1 0.15 0.28 0.94
173 INT134879 Negative_regulation of Phosphorylation of Nos1 1 0.50 0.27 0.93
174 INT42479 Positive_regulation of Negative_regulation of Lct 2 0.50 1 0.89
175 INT353148 Positive_regulation of Binding of SERPINA1 1 0.13 1.87 0.89
176 INT22592 Positive_regulation of Hmbs 2 0.48 2.27 0.87
177 INT154905 Negative_regulation of Phosphorylation of Cpox 1 0.18 0.91 0.87
178 INT114875 Negative_regulation of Cdk4 4 0.35 4.01 0.86
179 INT10047 Positive_regulation of Negative_regulation of SERPINA1 4 0.47 2.27 0.83
180 INT57135 Gene_expression of Hmbs 1 0.32 0.55 0.82
181 INT42655 Regulation of LCT 4 0.59 1.13 0.8
182 INT114877 Gene_expression of Cdk4 12 0.69 5.98 0.79
183 INT184415 Regulation of Positive_regulation of CRP 3 0.43 4.32 0.77
184 INT92618 Positive_regulation of LCT 9 0.48 3.54 0.75
185 INT35804 Regulation of Gene_expression of Hp 3 0.34 0.68 0.75
186 INT64172 Regulation of Transcription of CPOX 1 0.19 0.31 0.75
187 INT279202 Positive_regulation of Localization of CRP 3 0.69 2.45 0.72
188 INT152562 Regulation of Transcription of NOS3 1 0.23 0.34 0.71
189 INT114876 Negative_regulation of Gene_expression of Cdk4 3 0.38 2.3 0.7
190 INT131567 Negative_regulation of Positive_regulation of Bcl2l1 1 0.41 0.66 0.7
191 INT78800 Negative_regulation of Ncam1 2 0.36 0.58 0.69
192 INT43644 Binding of Lct 1 0.38 0 0.69
193 INT46392 Regulation of SERPINA1 4 0.44 2.23 0.68
194 INT193486 Negative_regulation of Negative_regulation of Nos3 3 0.34 2.21 0.68
195 INT131568 Positive_regulation of Positive_regulation of Bcl2l1 1 0.48 0.64 0.68
196 INT97192 Regulation of Transcription of Nos1 1 0.55 1.94 0.68
197 INT161361 Positive_regulation of Binding of Crp 1 0.07 2.45 0.68
198 INT90607 Positive_regulation of Binding of CPOX 4 0.17 0.79 0.67
199 INT272291 Regulation of Binding of CPOX 1 0.11 0.37 0.67
200 INT165611 Positive_regulation of Localization of Crp 4 0.36 4.68 0.64
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