GO:0010466

From wiki-pain
Jump to: navigation, search
Name negative regulation of peptidase activity
Categary Process
Go Slim No
Go Link GO:0010466
Unique Molecular Interactions 335
Total Molecular Interactions 454
Total Single Events 4634
Pain Genes Associated 35

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of peptidase activity. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of peptidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
2 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
3 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
4 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
5 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
6 INT123260 Binding of Gabrg2 and Serpini1 1 0.02 0.63 1.16
7 INT123261 Gabrg2 Regulation of Serpini1 1 0.01 0.63 1.16
8 INT224728 Col7a1 Positive_regulation of Cia1 1 0.00 2.9 1.12
9 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
10 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 0.01 1.2 0.79
11 INT328976 Binding of Cst7 and Cts 1 0.08 0.92 0.79
12 INT16488 Binding of Serpinf2 and Crp 1 0.00 0.78 0.78
13 INT16491 Binding of ADRA1D and Serpinf2 1 0.02 0.78 0.78
14 INT16494 Binding of LPA and Serpinf2 1 0.00 0.78 0.78
15 INT16492 Positive_regulation of Binding of LPA and Serpinf2 1 0.00 0.78 0.78
16 INT16493 Positive_regulation of Binding of ADRA1D and Serpinf2 1 0.02 0.78 0.78
17 INT16489 Positive_regulation of Binding of Serpinf2 and Crp 1 0.00 0.78 0.78
18 INT328980 Binding of Cst7 and Igfals 1 0.06 0.85 0.73
19 INT328983 Binding of Cst7 and Muted 1 0.04 0.84 0.73
20 INT328977 Binding of Cst7 and Mup1 1 0.18 0.84 0.73
21 INT117639 Serpini1 Negative_regulation of Cpox 1 0.00 0.64 0.72
22 INT126779 Binding of Serpinc1 and F8 1 0.00 1.52 0.69
23 INT126781 Binding of F10 and Serpinc1 1 0.00 1.51 0.69
24 INT250871 Il1a Positive_regulation of Protein_catabolism of Ecm1 1 0.01 1.44 0.68
25 INT329589 Serpina5 Positive_regulation of PTX3 1 0.03 1.52 0.66
26 INT333165 Binding of asa and Col7a1 1 0.03 0.94 0.63
27 INT2700 Binding of App and Cpe 1 0.00 0 0.63
28 INT84771 Positive_regulation of Binding of App and Pag1 1 0.17 0.9 0.62
29 INT179850 Binding of Ecm1 and Il11 1 0.02 0 0.6
30 INT120203 Binding of App and Il1 1 0.17 1.28 0.59
31 INT142993 Serpinc1 Positive_regulation of Phosphorylation of RHOA 1 0.05 0.05 0.59
32 INT120204 Binding of App and Il1f5 1 0.09 1.28 0.59
33 INT142990 Serpinc1 Positive_regulation of Phosphorylation of S1pr1 1 0.03 0.05 0.59
34 INT84770 Binding of App and Pag1 1 0.13 0.89 0.57
35 INT167618 Rho Regulation of App 1 0.17 0.88 0.55
36 INT129640 Binding of Ambp and Oprd1 1 0.22 0.19 0.55
37 INT167620 Rock2 Regulation of App 1 0.13 0.87 0.55
38 INT129639 Regulation of Binding of Ambp and Oprd1 1 0.17 0.19 0.55
39 INT99736 Binding of PLG and Serpinf2 1 0.01 0.73 0.55
40 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
41 INT204494 Binding of App and Fmr1 1 0.54 4.39 0.54
42 INT322048 Prkdc Negative_regulation of Col7a1 1 0.00 0.45 0.5
43 INT118485 CST3 Regulation of CTSH 1 0.36 0 0.49
44 INT224729 Negative_regulation of Col7a1 Positive_regulation of Cia1 1 0.00 1.02 0.48
45 INT250858 Mmp3 Regulation of Protein_catabolism of Ecm1 1 0.01 1.11 0.47
46 INT145260 Binding of CLU and App 1 0.00 0.74 0.46
47 INT167621 Psenen Positive_regulation of App 1 0.02 0.86 0.44
48 INT167617 Bace2 Positive_regulation of App 1 0.06 0.87 0.44
49 INT167619 Protein_catabolism of Ppp2cb Positive_regulation of App 1 0.00 0.88 0.44
50 INT191610 Binding of App and Drd3 1 0.20 0.7 0.42
51 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
52 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
53 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
54 INT69109 Acot1 Regulation of Gene_expression of Serpine2 1 0.04 0 0.4
55 INT78121 Positive_regulation of Binding of App and 20S 1 0.23 0.61 0.4
56 INT78122 Binding of App and 20S 1 0.16 0.61 0.4
57 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39
58 INT323967 Il6 Positive_regulation of Gene_expression of App 1 0.10 0.86 0.38
59 INT220052 Binding of Col7a1 and Cia1 1 0.01 1.11 0.38
60 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38
61 INT182052 Il18 Positive_regulation of Col7a1 1 0.03 0.74 0.38
62 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
63 INT99738 Binding of F13A1 and Serpinf2 1 0.00 0.49 0.37
64 INT335994 Timp1 Regulation of Col7a1 1 0.01 0.36 0.37
65 INT291625 Binding of CSTA and RAPGEF5 1 0.03 4.81 0.37
66 INT21828 Binding of POMC and Serpinb1a 1 0.02 0 0.36
67 INT206609 Binding of Col7a1 and Ecm1 1 0.00 0.47 0.33
68 INT206608 Binding of Ecm1 and Itgb5 1 0.02 0.41 0.33
69 INT180928 Binding of Col7a1 and Mmp9 1 0.03 0.96 0.32
70 INT308667 Binding of Chrm1 and Positive_regulation of Binding of App 1 0.04 1.14 0.32
71 INT332255 Ptger2 Positive_regulation of Localization of Col7a1 1 0.00 0.92 0.31
72 INT137308 sps Negative_regulation of Cstb 1 0.03 1.59 0.31
73 INT65268 Igf1 Positive_regulation of Col7a1 1 0.48 0 0.3
74 INT96096 Binding of Serpinc1 and Selp 1 0.00 0.69 0.3
75 INT291568 Artles Regulation of Cstb 1 0.00 0.7 0.3
76 INT15828 Ambp Regulation of Negative_regulation of Fn1 1 0.03 0 0.3
77 INT272925 Ccl2 Positive_regulation of Gene_expression of Col7a1 1 0.00 0.72 0.3
78 INT96101 Binding of SELP and Serpinc1 1 0.01 0.69 0.29
79 INT96093 Binding of Serpinc1 and F2 1 0.00 0.68 0.29
80 INT303440 Egf Positive_regulation of Gene_expression of Col7a1 1 0.07 0.92 0.28
81 INT24222 Ifng Positive_regulation of Gene_expression of Serping1 1 0.00 0 0.26
82 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
83 INT356094 Binding of App and Tg 1 0.08 0.12 0.26
84 INT188802 Il1 Negative_regulation of Gene_expression of Col7a1 1 0.00 0.71 0.26
85 INT41950 Ptger1 Positive_regulation of Localization of A2m 1 0.19 0.46 0.24
86 INT41949 Ptger1 Positive_regulation of Gene_expression of A2m 1 0.19 0.46 0.24
87 INT15829 Ambp Regulation of Positive_regulation of ELANE 1 0.00 0 0.24
88 INT336738 S100a8 Regulation of Gene_expression of Ambp 1 0.02 2.15 0.24
89 INT191619 Binding of App and Flna 1 0.04 0.18 0.24
90 INT128986 Binding of CST3 and Phdlc1 1 0.01 1.96 0.22
91 INT180670 Cpd Regulation of Protein_catabolism of Ecm1 1 0.04 0.14 0.22
92 INT45649 Tfpi Regulation of Regulation of LH 1 0.17 0 0.21
93 INT319971 App Regulation of Enpp1 1 0.02 0.72 0.21
94 INT45648 Tfpi Regulation of Regulation of Gh1 1 0.18 0 0.21
95 INT45651 Tfpi Regulation of Localization of LH 1 0.10 0 0.21
96 INT45650 Tfpi Regulation of Localization of Prl 1 0.19 0 0.2
97 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2
98 INT179683 Binding of Col7a1 and Eln 2 0.00 3.02 0.19
99 INT99731 Binding of Serpinf2 and Ppp1r1a 1 0.00 0.24 0.19
100 INT99734 Binding of SERPINE1 and Serpinf2 1 0.00 0.25 0.19
101 INT146687 Regulation of Binding of App and Aph1a 1 0.16 0.58 0.19
102 INT46308 Asrgl1 Positive_regulation of Gene_expression of Serpinc1 1 0.01 1.07 0.19
103 INT146686 Binding of App and Aph1a 1 0.14 0.58 0.19
104 INT46307 Asrgl1 Positive_regulation of Negative_regulation of Serpinc1 1 0.01 1.07 0.19
105 INT279507 Serping1 Negative_regulation of Gene_expression of C3 1 0.03 1.12 0.19
106 INT279500 Serping1 Negative_regulation of Transcription of C3 1 0.03 1.12 0.19
107 INT266046 Cstb Regulation of Gene_expression of Adrm1 1 0.00 0.7 0.18
108 INT261579 Serpinc1 Negative_regulation of Gene_expression of CYBB 1 0.00 1.69 0.18
109 INT310302 Tlr4 Regulation of Positive_regulation of Serpina10 1 0.01 0.53 0.18
110 INT310932 Binding of Tgm2 and Serpinb1a 1 0.04 0.87 0.17
111 INT329670 Csf2 Regulation of Col7a1 1 0.03 0.4 0.17
112 INT226536 Gene_expression of IL9 Positive_regulation of Positive_regulation of Col7a1 1 0.00 1.02 0.17
113 INT182326 LBR Positive_regulation of Gene_expression of Birc5 1 0.00 0.46 0.17
114 INT202312 PDGFB Positive_regulation of Gene_expression of Col7a1 1 0.01 0.7 0.16
115 INT319974 App Negative_regulation of Enpp1 1 0.02 0.58 0.16
116 INT310303 Serpina10 Positive_regulation of Hspa1a 1 0.02 0.53 0.16
117 INT204478 Fmr1 Regulation of Gene_expression of App 1 0.50 1.44 0.16
118 INT201744 Ngf Regulation of Transcription of App 1 0.06 0.39 0.15
119 INT201728 Ntrk1 Regulation of Transcription of App 1 0.03 0.39 0.15
120 INT21453 Ambp Regulation of ELANE 1 0.00 0 0.15
121 INT131304 Binding of Serping1 and Sele 1 0.01 1.07 0.15
122 INT259628 Cxcl10 Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.64 0.15
123 INT319972 App Negative_regulation of Gene_expression of Enpp1 1 0.02 1.87 0.15
124 INT109886 F2 Negative_regulation of Serpinc1 1 0.00 1.18 0.15
125 INT286476 Binding of App and Itm2b 1 0.47 5.24 0.14
126 INT310626 Ambp Regulation of OTOR 1 0.15 1.04 0.14
127 INT145055 Pebp1 Negative_regulation of Localization of Nr1i3 1 0.14 0.33 0.14
128 INT65272 Igf1 Positive_regulation of Binding of Col7a1 1 0.42 0 0.14
129 INT94763 PSEN2 Regulation of Positive_regulation of App 1 0.11 0.72 0.14
130 INT139849 Binding of App and Bace1 7 0.41 0.85 0.13
131 INT344135 Negative_regulation of Binding of Col7a1 and Lhyp 1 0.00 0.5 0.13
132 INT204489 Fmr1 Regulation of App 1 0.50 1.71 0.13
133 INT310313 Serpina10 Regulation of Gene_expression of Tlr4 1 0.00 0.25 0.13
134 INT136880 Pebp1 Positive_regulation of Localization of Ncoa6 1 0.33 0.06 0.13
135 INT250857 Gene_expression of Mmp3 Positive_regulation of Protein_catabolism of Ecm1 1 0.01 0.17 0.13
136 INT250907 Thbs2 Regulation of Col7a1 1 0.03 0.35 0.13
137 INT344134 Binding of Col7a1 and Lhyp 1 0.00 0.5 0.13
138 INT220622 App Positive_regulation of Rip 2 0.14 0.24 0.12
139 INT136883 Pebp1 Regulation of Localization of Casr 1 0.51 0 0.12
140 INT250869 Mia Positive_regulation of Protein_catabolism of Ecm1 1 0.01 0.25 0.12
141 INT289793 Binding of Comp and Ecm1 1 0.05 2.5 0.12
142 INT289790 Binding of Col7a1 and Comp 1 0.14 1.2 0.12
143 INT270355 Vcsa1 Positive_regulation of Negative_regulation of Mme 1 0.13 0.52 0.12
144 INT99737 Serpinf2 Negative_regulation of Localization of SERPINE1 1 0.00 0.24 0.12
145 INT99732 Serpinf2 Negative_regulation of PLG 1 0.01 0.24 0.12
146 INT336740 Positive_regulation of Ambp Positive_regulation of Gene_expression of S100a8 1 0.02 1.3 0.12
147 INT310305 Serpina10 Positive_regulation of Gene_expression of Tlr4 1 0.01 0.57 0.12
148 INT308660 Binding of Ager and App 1 0.08 1.22 0.12
149 INT182368 IgG Regulation of Cast 1 0.01 0.99 0.11
150 INT291622 HSD11B1 Regulation of CSTA 1 0.00 0.6 0.11
151 INT175985 Igf1 Positive_regulation of Gene_expression of Serpina1c 1 0.14 0.55 0.11
152 INT336632 Ecm1 Regulation of Regulation of Ahr 1 0.03 0.61 0.11
153 INT175987 Igf1 Positive_regulation of Serpina1c 1 0.13 0.54 0.11
154 INT279511 Binding of Serping1 and C1ra 1 0.01 0.3 0.11
155 INT204477 Binding of App and Scn10a 1 0.17 0.36 0.1
156 INT139847 Binding of App and Bace2 1 0.03 0.16 0.1
157 INT139850 Binding of MBTPS1 and App 1 0.00 0.16 0.1
158 INT5627 Tfpi Positive_regulation of Localization of Nppa 1 0.31 0.07 0.1
159 INT5626 Tfpi Positive_regulation of Transcription of Nppa 1 0.31 0.07 0.1
160 INT193963 App Regulation of Gene_expression of Ps 1 0.06 0.93 0.09
161 INT324829 ROS1 Positive_regulation of Gene_expression of Ecm1 1 0.00 0.66 0.09
162 INT316818 Sparc Regulation of Gene_expression of Col7a1 1 0.06 0.74 0.09
163 INT113363 Napa Positive_regulation of Serpina3c 1 0.15 0.25 0.09
164 INT348686 Plg Positive_regulation of Protein_catabolism of Ecm1 1 0.02 0.17 0.09
165 INT356112 Binding of App and Apba1 1 0.24 0.29 0.09
166 INT324828 ELANE Positive_regulation of Localization of Ecm1 1 0.00 0.61 0.09
167 INT113362 Gnat3 Positive_regulation of Serpina3c 1 0.17 0.25 0.09
168 INT262701 App Positive_regulation of Aplp2 1 0.12 0.25 0.09
169 INT316824 Negative_regulation of Sparc Negative_regulation of Gene_expression of Col7a1 1 0.10 0.82 0.09
170 INT262705 App Positive_regulation of Aplp1 1 0.13 0.25 0.09
171 INT124036 Binding of App and Dnahc8 1 0.03 0.14 0.09
172 INT291624 SERPINH1 Regulation of CSTA 1 0.00 0.39 0.09
173 INT336634 Fbln1 Positive_regulation of Ecm1 1 0.06 1.26 0.09
174 INT226044 Lta Positive_regulation of Ecm1 1 0.02 0.44 0.08
175 INT213239 Binding of TNXA and Serpinc1 1 0.00 0.16 0.08
176 INT259622 Elane Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.38 0.08
177 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
178 INT204487 Positive_regulation of Fmr1 Regulation of Gene_expression of App 1 0.30 0.8 0.08
179 INT175984 Igf1 Regulation of Localization of Serpina1c 1 0.14 0.54 0.08
180 INT304330 TGFB1 Positive_regulation of ECM1 1 0.00 0.31 0.08
181 INT21452 Ambp Regulation of Gene_expression of ELANE 1 0.00 0 0.08
182 INT179847 Binding of Ecm1 and Sparc 1 0.04 0 0.08
183 INT310310 Serpina10 Regulation of Gene_expression of Nos2 1 0.01 0.24 0.08
184 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07
185 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07
186 INT21446 Ambp Negative_regulation of Positive_regulation of Mpo 1 0.01 0 0.07
187 INT240484 Ctsk Positive_regulation of Protein_catabolism of Col7a1 1 0.12 0.42 0.07
188 INT192407 Col7a1 Positive_regulation of Gene_expression of Il2 1 0.01 0.09 0.07
189 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06
190 INT136875 Pebp1 Regulation of Localization of Ncoa6 1 0.37 0 0.06
191 INT136881 Ncoa6 Regulation of Pebp1 1 0.22 0 0.06
192 INT329429 Binding of Col7a1 and Hmgcr 1 0.01 0.28 0.06
193 INT310304 Serpina10 Negative_regulation of Gene_expression of Tlr4 1 0.01 0.25 0.06
194 INT136879 Ncoa6 Regulation of Localization of Pebp1 1 0.37 0 0.06
195 INT310308 Serpina10 Negative_regulation of Gene_expression of Gopc 1 0.01 0.25 0.06
196 INT198934 Binding of App and Lrp1b 2 0.27 1.62 0.05
197 INT288099 Binding of APP and App 1 0.01 1.04 0.05
198 INT179852 Binding of PTPRC and Ecm1 1 0.00 0 0.05
199 INT356086 Negative_regulation of Binding of App and Lrp1b 1 0.30 1.42 0.05
200 INT275126 Binding of CSTB and IGHG3 1 0.00 0.49 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of peptidase activity. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of peptidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65500 Gene_expression of App 605 0.78 429.94 98.31
2 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2
3 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
4 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
5 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
6 INT11625 Localization of App 98 0.78 55.46 20.86
7 INT63164 Negative_regulation of Cst7 51 0.50 18.48 20.3
8 INT16794 Binding of App 103 0.48 64.87 19.79
9 INT65502 Regulation of App 77 0.62 52.05 19.44
10 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42
11 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32
12 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38
13 INT65501 Regulation of Gene_expression of App 56 0.62 32.51 11.48
14 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15
15 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82
16 INT100661 Regulation of Cst7 18 0.53 5.93 7.8
17 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16
18 INT53704 Negative_regulation of Col7a1 42 0.35 22.4 6.88
19 INT166707 Protein_catabolism of Col7a1 24 0.74 20.47 6.39
20 INT171691 Protein_catabolism of Ecm1 31 0.20 11.57 6.38
21 INT60713 Binding of Col7a1 47 0.43 22.52 6.29
22 INT65265 Positive_regulation of Gene_expression of Col7a1 48 0.69 23.81 6.16
23 INT677 Positive_regulation of CST3 20 0.67 17.47 6
24 INT4587 Negative_regulation of Serping1 32 0.47 19.11 5.92
25 INT55101 Gene_expression of Cst7 16 0.75 2.39 5.92
26 INT179810 Protein_catabolism of Ecm1 30 0.11 18.28 5.75
27 INT107173 Phosphorylation of App 20 0.82 12.64 5.3
28 INT134966 Localization of Col7a1 23 0.42 16.4 5.24
29 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16
30 INT187295 Gene_expression of Serpinb1a 6 0.58 13.73 5.05
31 INT20200 Positive_regulation of Serpinc1 25 0.68 17.08 4.98
32 INT116464 Negative_regulation of Birc5 53 0.59 45.4 4.91
33 INT131692 Negative_regulation of Localization of App 9 0.53 4.69 4.82
34 INT6005 Gene_expression of Serpini1 5 0.58 1.62 4.74
35 INT134968 Localization of Ecm1 20 0.32 27.27 4.31
36 INT3826 Positive_regulation of Tfpi 10 0.61 2.26 4.16
37 INT182311 Positive_regulation of Birc5 26 0.67 25.32 4.08
38 INT41942 Gene_expression of A2m 9 0.36 9.98 3.96
39 INT92678 Positive_regulation of Ecm1 30 0.09 28.41 3.68
40 INT11627 Positive_regulation of Localization of App 14 0.62 6.27 3.64
41 INT132187 Gene_expression of Ecm1 14 0.21 8.12 3.52
42 INT157805 Negative_regulation of Gene_expression of Col7a1 22 0.34 12.85 3.51
43 INT8539 Negative_regulation of Serpina1a 21 0.58 12.65 3.39
44 INT171233 Binding of Ecm1 25 0.07 12.41 3.36
45 INT14397 Gene_expression of Serpinc1 27 0.46 14.54 3.32
46 INT20146 Localization of Tfpi 5 0.81 1.21 3.11
47 INT37405 Positive_regulation of Cst7 7 0.49 3.32 2.99
48 INT108773 Negative_regulation of Binding of App 10 0.42 7.26 2.96
49 INT69099 Gene_expression of Serpine2 22 0.78 7.89 2.87
50 INT178772 Transcription of App 17 0.70 10.79 2.79
51 INT147429 Negative_regulation of Positive_regulation of App 8 0.40 8.73 2.78
52 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74
53 INT120372 Positive_regulation of Ambp 21 0.21 21.1 2.66
54 INT6928 Regulation of Tfpi 4 0.26 1.06 2.61
55 INT65258 Regulation of Gene_expression of Col7a1 17 0.55 8.26 2.57
56 INT5180 Binding of Serpinc1 27 0.36 13.39 2.47
57 INT181986 Negative_regulation of Positive_regulation of Col7a1 6 0.08 7.4 2.46
58 INT60142 Negative_regulation of Serpinb1a 2 0.42 0.59 2.46
59 INT134964 Regulation of Ecm1 13 0.10 7.45 2.37
60 INT160080 Localization of Ecm1 6 0.15 4.86 2.36
61 INT4585 Gene_expression of Serping1 19 0.46 12.4 2.35
62 INT11626 Regulation of Localization of App 4 0.45 1.51 2.34
63 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32
64 INT160673 Gene_expression of Ambp 16 0.49 19.49 2.3
65 INT182318 Regulation of Birc5 25 0.60 23.58 2.29
66 INT640 Regulation of CST3 9 0.60 4.04 2.26
67 INT124772 Regulation of Binding of App 6 0.45 4.92 2.09
68 INT130754 Gene_expression of Cast 21 0.78 11.6 2.08
69 INT11745 Protein_catabolism of Cst7 3 0.39 0.81 2.08
70 INT242856 Binding of Cst7 2 0.18 3.04 1.93
71 INT142774 Regulation of Phosphorylation of App 1 0.59 2.27 1.93
72 INT14500 Positive_regulation of Gene_expression of CST3 9 0.67 7.46 1.87
73 INT16391 Regulation of Serpinf2 5 0.03 4.22 1.82
74 INT6006 Positive_regulation of Gene_expression of Serpini1 1 0.00 0 1.82
75 INT3827 Gene_expression of Tfpi 5 0.53 0.36 1.81
76 INT121117 Regulation of Protein_catabolism of App 10 0.62 6.41 1.78
77 INT67183 Binding of Serpinb1a 4 0.37 4 1.77
78 INT107915 Regulation of Negative_regulation of App 6 0.45 4.47 1.76
79 INT41639 Positive_regulation of A2m 7 0.46 4.52 1.74
80 INT134965 Negative_regulation of Ecm1 7 0.18 7.86 1.7
81 INT156671 Gene_expression of Vcsa1 22 0.75 23.32 1.69
82 INT166131 Positive_regulation of Positive_regulation of Col7a1 8 0.46 6.4 1.65
83 INT146338 Positive_regulation of Cstb 4 0.38 4.25 1.64
84 INT180678 Negative_regulation of Protein_catabolism of Ecm1 6 0.08 2.69 1.61
85 INT60975 Localization of CST3 6 0.78 2.4 1.58
86 INT133863 Positive_regulation of Protein_catabolism of App 12 0.59 7.53 1.52
87 INT23186 Positive_regulation of Positive_regulation of Tfpi 1 0.44 0 1.48
88 INT159102 Regulation of Ecm1 9 0.16 1.28 1.41
89 INT129700 Regulation of Positive_regulation of App 3 0.43 1.86 1.41
90 INT72359 Binding of Serpini1 3 0.32 1.02 1.39
91 INT65261 Regulation of Col7a1 18 0.55 8.7 1.33
92 INT35728 Positive_regulation of Vcsa1 4 0.48 0.87 1.3
93 INT41944 Positive_regulation of Gene_expression of A2m 2 0.23 2.56 1.29
94 INT169525 Positive_regulation of Serpinb1a 4 0.44 6.48 1.24
95 INT35729 Positive_regulation of Positive_regulation of Vcsa1 1 0.31 0.3 1.23
96 INT679 Negative_regulation of CST3 7 0.57 4.63 1.22
97 INT96845 Positive_regulation of Regulation of Serpinc1 1 0.18 1.78 1.22
98 INT57494 Positive_regulation of Positive_regulation of Serpinc1 3 0.26 1.67 1.19
99 INT130755 Positive_regulation of Gene_expression of Cast 4 0.70 4.3 1.18
100 INT14396 Regulation of Serpinc1 5 0.19 3.16 1.16
101 INT100137 Positive_regulation of Negative_regulation of App 2 0.41 1.26 1.16
102 INT41947 Regulation of A2m 2 0.29 1.08 1.14
103 INT36064 Binding of CST3 14 0.47 16.38 1.12
104 INT11109 Positive_regulation of Serpina1a 5 0.68 4.97 1.12
105 INT16393 Gene_expression of Serpinf2 4 0.08 3.39 1.09
106 INT60711 Negative_regulation of Binding of Col7a1 4 0.36 2.91 1.04
107 INT86931 Gene_expression of A2m 3 0.16 4.81 1.04
108 INT180683 Positive_regulation of Protein_catabolism of Ecm1 9 0.09 2.25 1.03
109 INT26508 Regulation of Serpini1 2 0.19 0.84 1.01
110 INT305307 Gene_expression of Serpina5 88 0.78 10.09 1
111 INT294191 Localization of Serpini1 3 0.67 1.21 0.99
112 INT106152 Negative_regulation of Regulation of Cst7 1 0.36 0.69 0.99
113 INT182313 Regulation of Gene_expression of Birc5 18 0.60 15.34 0.96
114 INT77093 Positive_regulation of Serpina3c 1 0.67 1.31 0.95
115 INT169467 Gene_expression of Spink3 3 0.57 2.65 0.93
116 INT63037 Regulation of CSTA 10 0.37 13.37 0.92
117 INT248774 Positive_regulation of Localization of Ecm1 4 0.05 8.46 0.92
118 INT166708 Negative_regulation of Protein_catabolism of Col7a1 2 0.32 2.62 0.92
119 INT16479 Positive_regulation of Serpinf2 2 0.05 1.2 0.9
120 INT55102 Positive_regulation of Gene_expression of Cst7 1 0.41 0.05 0.89
121 INT41946 Localization of A2m 1 0.38 1.81 0.89
122 INT167607 Positive_regulation of Binding of App 8 0.50 2.97 0.86
123 INT179814 Positive_regulation of Protein_catabolism of Ecm1 5 0.06 3.38 0.85
124 INT167374 Transcription of Col7a1 4 0.17 2.9 0.85
125 INT17804 Negative_regulation of Ambp 2 0.31 2.03 0.85
126 INT151907 Binding of Ecm1 6 0.11 2.48 0.83
127 INT167373 Positive_regulation of Transcription of Col7a1 2 0.12 1.82 0.79
128 INT250847 Negative_regulation of Ecm1 1 0.03 1.72 0.78
129 INT41943 Positive_regulation of Positive_regulation of A2m 2 0.22 1.19 0.74
130 INT316727 Positive_regulation of Localization of Serpini1 1 0.08 0.76 0.73
131 INT146109 Positive_regulation of Serping1 4 0.59 2.73 0.68
132 INT41945 Negative_regulation of A2m 2 0.27 0.35 0.68
133 INT103623 Negative_regulation of Serpini1 2 0.02 0.15 0.68
134 INT109603 Positive_regulation of Localization of CST3 1 0.45 0.61 0.67
135 INT310292 Gene_expression of Serpina10 1 0.03 4.13 0.67
136 INT112649 Negative_regulation of Serpine2 10 0.43 1.41 0.66
137 INT23348 Negative_regulation of Serpinf2 8 0.38 3.02 0.65
138 INT171692 Regulation of Protein_catabolism of Ecm1 4 0.12 1.5 0.65
139 INT211782 Localization of Ambp 2 0.26 2.12 0.64
140 INT16392 Protein_catabolism of Serpinf2 1 0.03 1.38 0.64
141 INT156960 Localization of Vcsa1 2 0.77 1.46 0.62
142 INT125553 Negative_regulation of Positive_regulation of Cst7 1 0.37 0.55 0.62
143 INT159551 Regulation of Cstb 4 0.06 2.46 0.61
144 INT96844 Regulation of Positive_regulation of Serpinc1 1 0.10 0.89 0.61
145 INT22784 Positive_regulation of Serpina1c 3 0.20 1.11 0.6
146 INT146108 Regulation of Positive_regulation of Serping1 1 0.05 1.04 0.6
147 INT142112 Regulation of Regulation of App 3 0.39 2.46 0.59
148 INT69100 Regulation of Gene_expression of Serpine2 1 0.18 0 0.59
149 INT179337 Positive_regulation of Gene_expression of Ecm1 14 0.05 3.73 0.58
150 INT142988 Regulation of Gene_expression of Serpinc1 1 0.04 0.56 0.58
151 INT63035 Gene_expression of CSTA 10 0.56 11.56 0.57
152 INT6927 Negative_regulation of Tfpi 3 0.41 2.79 0.57
153 INT182317 Binding of Birc5 8 0.32 4.63 0.56
154 INT79839 Positive_regulation of Serpina5 3 0.44 1.2 0.56
155 INT171693 Positive_regulation of Ecm1 5 0.09 2.14 0.55
156 INT132186 Negative_regulation of Gene_expression of Ecm1 2 0.06 1.73 0.54
157 INT193108 Negative_regulation of Negative_regulation of Birc5 6 0.42 5.25 0.53
158 INT77094 Negative_regulation of Positive_regulation of Serpina3c 1 0.41 0.68 0.53
159 INT137412 Negative_regulation of Cast 6 0.49 4.03 0.52
160 INT150323 Gene_expression of Cstb 5 0.67 3.31 0.52
161 INT60712 Positive_regulation of Binding of Col7a1 2 0.43 0.53 0.52
162 INT143402 Positive_regulation of Binding of Serpini1 1 0.08 0 0.52
163 INT136303 Regulation of Serpina3f 1 0.44 0.85 0.52
164 INT187090 Positive_regulation of Localization of Col7a1 4 0.07 3.16 0.51
165 INT78117 Positive_regulation of Positive_regulation of App 4 0.48 2.6 0.51
166 INT156959 Regulation of Localization of Vcsa1 1 0.21 0.9 0.51
167 INT167366 Positive_regulation of A2m 1 0.02 0.43 0.49
168 INT29235 Negative_regulation of Localization of Tfpi 1 0.26 0 0.49
169 INT112651 Positive_regulation of Gene_expression of Serpine2 3 0.70 3.36 0.47
170 INT5179 Negative_regulation of Binding of Serpinc1 1 0.01 0.15 0.47
171 INT45647 Negative_regulation of Gene_expression of Tfpi 1 0.29 0 0.47
172 INT182315 Positive_regulation of Negative_regulation of Birc5 2 0.45 1.79 0.46
173 INT250837 Positive_regulation of Negative_regulation of Ecm1 1 0.04 1.1 0.44
174 INT39072 Negative_regulation of Positive_regulation of Serpinc1 2 0.36 1.24 0.43
175 INT305084 Positive_regulation of Gene_expression of Serpinb1a 1 0.11 0.94 0.43
176 INT223880 Positive_regulation of Negative_regulation of Cst7 1 0.40 0 0.43
177 INT205725 Regulation of Regulation of Ecm1 1 0.03 0.1 0.4
178 INT137410 Positive_regulation of Cast 4 0.70 4.37 0.39
179 INT20147 Positive_regulation of Localization of Tfpi 1 0.41 0.18 0.38
180 INT182314 Transcription of Birc5 4 0.69 2.69 0.37
181 INT288336 Positive_regulation of Gene_expression of A2m 1 0.12 1.73 0.37
182 INT182319 Localization of Birc5 6 0.75 5.13 0.34
183 INT8540 Gene_expression of Serpina1a 5 0.66 3.99 0.34
184 INT250834 Negative_regulation of Localization of Ecm1 1 0.04 0.58 0.34
185 INT187790 Negative_regulation of Gene_expression of Serpine2 2 0.37 1.23 0.33
186 INT178773 Positive_regulation of Regulation of App 2 0.49 1.01 0.32
187 INT103190 Positive_regulation of Phosphorylation of Col7a1 1 0.02 0.99 0.32
188 INT103195 Phosphorylation of Col7a1 1 0.03 0.98 0.32
189 INT178774 Positive_regulation of Transcription of App 2 0.49 1.17 0.31
190 INT109604 Negative_regulation of Localization of CST3 1 0.41 0.31 0.31
191 INT27363 Negative_regulation of Gene_expression of Serpinc1 5 0.29 3.2 0.3
192 INT131301 Binding of Serping1 3 0.28 1.86 0.3
193 INT137409 Negative_regulation of Positive_regulation of Cast 1 0.38 0.95 0.3
194 INT59448 Negative_regulation of Negative_regulation of Serpina1a 1 0.00 0.79 0.3
195 INT270341 Positive_regulation of Gene_expression of Vcsa1 3 0.57 1.12 0.29
196 INT171220 Regulation of Serpine2 3 0.20 0.1 0.28
197 INT4586 Negative_regulation of Gene_expression of Serping1 3 0.30 2.12 0.28
198 INT274681 Positive_regulation of Protein_catabolism of Col7a1 2 0.05 1.18 0.28
199 INT175121 Gene_expression of Serpina3f 4 0.75 0.41 0.27
200 INT310290 Positive_regulation of Serpina10 1 0.02 1.05 0.26
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox