GO:0010477

From wiki-pain
Jump to: navigation, search
Name response to sulfur dioxide
Categary Process
Go Slim No
Go Link GO:0010477
Unique Molecular Interactions 103
Total Molecular Interactions 177
Total Single Events 1957
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to sulfur dioxide. They are ordered first by their pain relevance and then by number of times they were reported for response to sulfur dioxide. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
2 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
3 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
4 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
5 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
6 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
7 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
8 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22
9 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
10 INT139230 Icam1 Negative_regulation of Cmklr1 1 0.19 1.13 1.07
11 INT139227 Icam1 Negative_regulation of Timp1 1 0.37 1.13 1.06
12 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
13 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
14 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
15 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91
16 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77
17 INT132166 PSG7 Positive_regulation of Muc5ac 1 0.00 0 0.73
18 INT70998 IL1B Regulation of Gene_expression of Icam1 1 0.44 0.95 0.67
19 INT334133 Acsm3 Positive_regulation of Icam1 1 0.23 1.61 0.66
20 INT66603 TFF2 Positive_regulation of Gene_expression of ICAM1 1 0.02 0 0.64
21 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
22 INT66601 WDR87 Positive_regulation of Gene_expression of ICAM1 1 0.00 0 0.63
23 INT66604 SARDH Positive_regulation of Gene_expression of ICAM1 1 0.01 0 0.63
24 INT176475 IL1B Positive_regulation of Gene_expression of ICAM1 1 0.02 0.56 0.62
25 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61
26 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57
27 INT66600 TFF2 Regulation of Positive_regulation of ICAM1 1 0.01 0 0.56
28 INT133049 TNF Positive_regulation of ICAM1 4 0.47 2.49 0.54
29 INT137137 Binding of HIVEP1 and ICAM1 1 0.01 0.68 0.51
30 INT92997 Positive_regulation of SFTPA1 Positive_regulation of Binding of ICAM1 1 0.15 0.26 0.51
31 INT289464 Negative_regulation of IRF6 Positive_regulation of ICAM1 1 0.07 0.31 0.5
32 INT135586 CSF2 Regulation of ICAM1 1 0.13 1.3 0.49
33 INT71178 Binding of ITGB2 and Icam1 1 0.45 1.2 0.47
34 INT132171 PSG7 Positive_regulation of Localization of Muc5ac 1 0.00 0 0.39
35 INT249090 FOXL1 Regulation of Regulation of ICAM1 1 0.12 1.03 0.37
36 INT210952 Il1 Positive_regulation of Gene_expression of Icam1 1 0.01 0.86 0.37
37 INT78893 TNF Regulation of Gene_expression of ICAM1 1 0.24 0.38 0.35
38 INT193492 Binding of Icam1 and Sele 1 0.06 1.05 0.34
39 INT132172 PSG7 Positive_regulation of Gene_expression of Muc5ac 1 0.00 0 0.34
40 INT306942 Tnfsf12 Positive_regulation of Gene_expression of ICAM1 1 0.04 1.78 0.27
41 INT170258 Pecam1 Positive_regulation of Icam1 1 0.02 0.79 0.27
42 INT239396 Atp7b Negative_regulation of Gene_expression of Icam1 1 0.07 1.69 0.26
43 INT128644 Binding of Icam1 and Selp 2 0.39 0.57 0.25
44 INT129220 IFNG Positive_regulation of ICAM1 1 0.09 0.1 0.25
45 INT179200 Binding of ICAM1 and IL8 1 0.03 1.02 0.25
46 INT129219 IFNG Positive_regulation of Gene_expression of ICAM1 1 0.13 0.1 0.25
47 INT57172 Binding of RYBP and Cyp2b1 1 0.02 0 0.23
48 INT284589 Binding of ICAM1 and Crp 1 0.00 1.08 0.22
49 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
50 INT141490 Negative_regulation of TNF Positive_regulation of ICAM1 1 0.29 0.58 0.21
51 INT139454 Binding of IGF2R and Icam1 1 0.00 0.4 0.21
52 INT158199 Negative_regulation of Binding of ICAM1 and AHSA1 1 0.15 0.3 0.2
53 INT158220 Positive_regulation of Binding of ICAM1 and TNFSF14 1 0.05 0.3 0.2
54 INT158223 Binding of ICAM1 and TNFSF14 1 0.04 0.3 0.2
55 INT158218 Binding of ICAM1 and AHSA1 1 0.14 0.3 0.2
56 INT158227 Negative_regulation of Binding of ICAM1 and MAPK1 1 0.16 0.3 0.2
57 INT158236 Positive_regulation of Binding of ICAM1 and MAPK1 1 0.19 0.3 0.2
58 INT158226 Binding of ICAM1 and MAPK1 1 0.14 0.3 0.2
59 INT158213 Positive_regulation of Binding of ICAM1 and AHSA1 1 0.18 0.3 0.2
60 INT158229 Negative_regulation of Binding of ICAM1 and TNFSF14 1 0.05 0.3 0.2
61 INT125152 IL1B Regulation of Gene_expression of ICAM1 1 0.50 0.1 0.2
62 INT158215 TNFSF14 Positive_regulation of ICAM1 1 0.05 0.3 0.2
63 INT214590 TIMP1 Regulation of ICAM1 1 0.10 0.29 0.19
64 INT214591 FOXC1 Regulation of ICAM1 1 0.05 0.29 0.19
65 INT214592 OAP Regulation of Gene_expression of ICAM1 1 0.02 0.77 0.19
66 INT171945 PECAM1 Positive_regulation of Gene_expression of ICAM1 1 0.06 1.66 0.16
67 INT171544 PECAM1 Positive_regulation of ICAM1 1 0.01 0.47 0.16
68 INT171944 ICAM1 Positive_regulation of Gene_expression of PECAM1 1 0.06 1.66 0.16
69 INT63981 Sele Regulation of Positive_regulation of Icam1 1 0.17 0.71 0.15
70 INT63980 Icam1 Regulation of Positive_regulation of Sele 1 0.17 0.71 0.15
71 INT289956 Binding of APC and ICAM1 1 0.04 0.5 0.13
72 INT57170 Binding of Cyp1a1 and Cyp2b1 1 0.39 0 0.13
73 INT294742 Lep Positive_regulation of Localization of Icam1 1 0.15 0.48 0.11
74 INT269785 Crp Positive_regulation of ICAM1 1 0.00 1.68 0.11
75 INT297938 Binding of ICAM1 and PAOD1 1 0.06 0.86 0.11
76 INT120700 PRSS1 Positive_regulation of ICAM1 1 0.15 0.29 0.1
77 INT277089 VEGFA Positive_regulation of Icam1 1 0.02 1.74 0.09
78 INT355580 VEGFA Positive_regulation of ICAM1 1 0.09 1.39 0.09
79 INT267626 Il1 Positive_regulation of ICAM1 1 0.00 0.79 0.09
80 INT323640 Vcam1 Positive_regulation of Gene_expression of Icam1 1 0.42 1.75 0.08
81 INT346136 ADM Positive_regulation of ICAM1 1 0.20 0.92 0.08
82 INT80930 Tnf Positive_regulation of Negative_regulation of Cyp2b1 1 0.10 0.21 0.08
83 INT267137 ICAM1 Regulation of ITGAL 2 0.12 0.57 0.07
84 INT284501 Positive_regulation of Binding of ICAM1 and ITGAL 1 0.06 0.2 0.07
85 INT19725 Cyp2b1 Positive_regulation of Cyp2c22 1 0.02 0 0.07
86 INT284503 Binding of ICAM1 and ITGAM 1 0.05 0.2 0.07
87 INT186814 MIR181A2HG Regulation of ICAM1 1 0.01 1.05 0.07
88 INT313506 Binding of ICAM1 and SNRNP70 1 0.02 1.08 0.06
89 INT313501 Binding of ALOX12 and ICAM1 1 0.10 0.54 0.03
90 INT285407 ELF3 Regulation of ICAM1 1 0.03 0.91 0.03
91 INT251006 ICAM1 Positive_regulation of SELL 1 0.02 0.56 0
92 INT132220 Muc5ac Regulation of Gene_expression of KRT7 1 0.01 0.18 0
93 INT285289 TNF Positive_regulation of Icam1 1 0.23 1.44 0
94 INT170587 GOPC Regulation of Gene_expression of ICAM1 1 0.13 0 0
95 INT74217 Oprl1 Negative_regulation of Positive_regulation of Icam1 1 0.18 0.11 0
96 INT249996 Binding of ICAM1 and GPHA2 1 0.02 2.25 0
97 INT249995 Positive_regulation of Binding of ICAM1 and GPHA2 1 0.02 2.43 0
98 INT170590 RELA Negative_regulation of Gene_expression of ICAM1 1 0.42 0.49 0
99 INT285288 TNF Positive_regulation of Gene_expression of Icam1 1 0.17 2.83 0
100 INT170588 RELA Regulation of Gene_expression of ICAM1 1 0.26 0 0
101 INT170589 NFKB1 Regulation of Gene_expression of ICAM1 1 0.27 0 0
102 INT155171 ICAM1 Regulation of Gene_expression of NOS1 1 0.09 0.08 0
103 INT132221 Muc5ac Regulation of KRT7 1 0.01 0.18 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to sulfur dioxide. They are ordered first by their pain relevance and then by number of times they were reported in response to sulfur dioxide. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
2 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71
3 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28
4 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55
5 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54
6 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61
7 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72
8 INT65713 Localization of ICAM1 42 0.81 39.55 11.49
9 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96
10 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15
11 INT80549 Binding of ICAM1 53 0.47 42.76 9.72
12 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5
13 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06
14 INT62944 Regulation of Icam1 33 0.47 23.52 7.94
15 INT48404 Regulation of Gene_expression of Icam1 21 0.62 15.1 7.81
16 INT71727 Negative_regulation of Icam1 25 0.45 17.76 5.73
17 INT65712 Positive_regulation of Localization of ICAM1 14 0.70 16.72 5.5
18 INT70996 Positive_regulation of Positive_regulation of Icam1 8 0.60 6.02 3.74
19 INT70994 Negative_regulation of Positive_regulation of Icam1 8 0.51 3.49 3.12
20 INT74216 Binding of Icam1 16 0.48 10.11 2.69
21 INT135470 Transcription of Icam1 10 0.63 12.04 2.41
22 INT72865 Localization of Icam1 12 0.68 8.18 2.24
23 INT53392 Positive_regulation of Cyp2b1 8 0.68 0.68 2.13
24 INT111575 Gene_expression of Muc5ac 15 0.78 7.97 1.84
25 INT70993 Regulation of Positive_regulation of Icam1 2 0.45 1.22 1.57
26 INT12842 Binding of Cyp2b1 4 0.48 0 1.56
27 INT78816 Positive_regulation of Positive_regulation of ICAM1 9 0.68 8.36 1.55
28 INT93005 Positive_regulation of Binding of ICAM1 5 0.68 4.55 1.42
29 INT83464 Positive_regulation of Localization of Icam1 3 0.46 3.71 1.4
30 INT62824 Negative_regulation of Positive_regulation of ICAM1 7 0.53 2.94 1.39
31 INT63339 Transcription of ICAM1 6 0.69 3.92 1.37
32 INT57169 Gene_expression of Cyp2b1 5 0.72 1.39 1.2
33 INT199009 Negative_regulation of Transcription of Icam1 4 0.38 3.81 0.95
34 INT111568 Transcription of Muc5ac 1 0.53 0.5 0.75
35 INT66607 Regulation of Positive_regulation of ICAM1 3 0.42 2.81 0.71
36 INT111566 Regulation of Transcription of Muc5ac 1 0.27 0.43 0.65
37 INT34755 Negative_regulation of Cyp2b1 5 0.56 1.2 0.61
38 INT53391 Negative_regulation of Positive_regulation of Cyp2b1 2 0.41 0.24 0.61
39 INT154728 Regulation of Gene_expression of Cyp2b1 1 0.42 0 0.59
40 INT111574 Localization of Muc5ac 2 0.80 0.1 0.53
41 INT78813 Positive_regulation of Transcription of ICAM1 1 0.46 0.16 0.5
42 INT112949 Negative_regulation of Binding of Icam1 2 0.24 1.75 0.47
43 INT111571 Regulation of Gene_expression of Muc5ac 1 0.45 0.28 0.42
44 INT158244 Phosphorylation of ICAM1 2 0.67 1.33 0.39
45 INT177231 Regulation of Regulation of ICAM1 1 0.06 0.66 0.37
46 INT267145 Negative_regulation of Binding of ICAM1 5 0.57 4.12 0.33
47 INT214613 Regulation of Binding of ICAM1 2 0.28 1.41 0.32
48 INT294738 Positive_regulation of Transcription of Icam1 2 0.44 1.74 0.24
49 INT130888 Regulation of Muc5ac 1 0.09 0.92 0.23
50 INT111570 Positive_regulation of Gene_expression of Muc5ac 1 0.50 0.14 0.21
51 INT174246 Localization of Cyp2b1 2 0.68 1.58 0.17
52 INT146186 Negative_regulation of Negative_regulation of Icam1 1 0.11 0.86 0.17
53 INT112950 Positive_regulation of Binding of Icam1 1 0.28 0.73 0.15
54 INT111572 Positive_regulation of Transcription of Muc5ac 1 0.47 0.08 0.12
55 INT214610 Regulation of Localization of ICAM1 1 0.28 0 0.11
56 INT111569 Negative_regulation of Gene_expression of Muc5ac 1 0.59 0.07 0.1
57 INT115830 Negative_regulation of Gene_expression of Cyp2b1 1 0.37 0.44 0.07
58 INT267150 Regulation of Transcription of ICAM1 2 0.26 0.86 0.06
59 INT54293 Protein_catabolism of Cyp2b1 1 0.86 0 0.06
60 INT107191 Positive_regulation of Regulation of Icam1 1 0.44 0.87 0.05
61 INT324011 Negative_regulation of Muc5ac 1 0.20 0 0.04
62 INT139002 Negative_regulation of Negative_regulation of ICAM1 1 0.02 0.1 0
63 INT349474 Regulation of Binding of Icam1 1 0.25 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox