GO:0010494

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Name cytoplasmic stress granule
Categary Component
Go Slim No
Go Link GO:0010494
Unique Molecular Interactions 68
Total Molecular Interactions 108
Total Single Events 431
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cytoplasmic stress granule. They are ordered first by their pain relevance and then by number of times they were reported for cytoplasmic stress granule. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT295411 Grb7 Positive_regulation of Oprk1 1 0.02 1.03 0.57
2 INT278227 Binding of MBNL1 and SNRNP70 1 0.01 2.05 0.54
3 INT350150 Binding of LPP and ATXN2 1 0.35 1.82 0.54
4 INT278228 Binding of MBNL1 and NOS3 1 0.05 2.06 0.54
5 INT149652 Zfp36 Regulation of Nos2 1 0.09 0.42 0.47
6 INT295354 Ntn1 Positive_regulation of Grb7 1 0.04 0.51 0.29
7 INT130714 CA2 Positive_regulation of Eif2s1 1 0.16 0.59 0.24
8 INT131963 Binding of CAV2 and ATXN2 1 0.04 1.39 0.21
9 INT350152 Binding of ATXN2 and SNRNP70 1 0.13 1.22 0.2
10 INT324815 Binding of Hmgb1 and Caprin1 1 0.01 0.65 0.19
11 INT350702 Rc3h1 Positive_regulation of Protein_catabolism of Icos 1 0.35 1.56 0.18
12 INT44903 Binding of EIF2S1 and Sergef 1 0.02 0.32 0.17
13 INT275461 Binding of Atxn1 and Atxn2 1 0.39 1.1 0.17
14 INT71328 Cacna1a Regulation of Atxn2 1 0.00 0.71 0.15
15 INT295336 Binding of Grb7 and Xpo1 1 0.09 0.31 0.15
16 INT346411 Binding of Caprin1 and Mtus1 1 0.00 0.17 0.14
17 INT346410 Binding of Caprin1 and Tesc 1 0.00 0.17 0.14
18 INT350694 Uts2r Negative_regulation of Negative_regulation of Rc3h1 1 0.05 0.79 0.1
19 INT295357 Binding of Hua and Grb7 1 0.26 0.2 0.1
20 INT277313 Negative_regulation of Mbnl1 Positive_regulation of Positive_regulation of Slc6a11 1 0.52 0.08 0.08
21 INT295348 Hua Positive_regulation of Localization of Grb7 1 0.33 0.14 0.07
22 INT295405 Binding of Oprk1 and Grb7 1 0.02 0.09 0.05
23 INT295352 Egf Positive_regulation of Grb7 1 0.42 0.06 0.03
24 INT260946 Zfp36 Negative_regulation of Binding of Elavl1 1 0.21 0.11 0.03
25 INT295349 Binding of Ptpn11 and Grb7 1 0.13 0.11 0.03
26 INT295343 Negative_regulation of Egf Positive_regulation of Grb7 1 0.38 0.06 0.03
27 INT255143 Regulation of Binding of Mbnl1 and Hnrnph1 1 0.07 0.07 0
28 INT311298 Binding of DMPK and Mbnl1 1 0.43 0.54 0
29 INT311390 Mbnl1 Positive_regulation of Celf1 1 0.26 0.48 0
30 INT311387 Binding of Celf1 and Mbnl1 1 0.20 0.25 0
31 INT339104 Binding of ERBB2 and GRB7 1 0.30 1.29 0
32 INT277315 Binding of Insr and Mbnl1 1 0.18 1.1 0
33 INT339117 Binding of EGFR and GRB7 1 0.28 1.18 0
34 INT300901 Binding of IGF2 and IGF2BP1 1 0.04 0.71 0
35 INT44886 Binding of EIF2S1 and MET 1 0.25 0.15 0
36 INT311379 Celf1 Negative_regulation of Mbnl1 1 0.24 0.26 0
37 INT229935 YBX1 Negative_regulation of C4B 1 0.00 0 0
38 INT311380 Positive_regulation of Celf1 Negative_regulation of Mbnl1 1 0.26 0.26 0
39 INT255147 Binding of Dmpk and Mbnl1 1 0.34 0 0
40 INT277311 Mbnl1 Regulation of Gene_expression of Slc6a11 1 0.50 0.06 0
41 INT189560 Binding of MBNL1 and CCNL1 1 0.12 0.22 0
42 INT295350 Egf Positive_regulation of Binding of Grb7 1 0.42 0 0
43 INT295346 Egf Positive_regulation of Phosphorylation of Grb7 1 0.42 0 0
44 INT295339 Binding of Grb7 and She 1 0.04 0 0
45 INT255145 Binding of Mbnl1 and Hnrnph1 1 0.09 0.15 0
46 INT277312 Regulation of Binding of Upf1 and Mbnl1 1 0.01 0.36 0
47 INT295359 Ptpn11 Regulation of Phosphorylation of Grb7 1 0.10 0 0
48 INT300900 Binding of MYC and IGF2BP1 1 0.06 0.71 0
49 INT352841 Binding of Miox and Lin28a 1 0.00 0 0
50 INT311383 Mbnl1 Regulation of Insr 1 0.00 0.24 0
51 INT277309 Binding of Upf1 and Mbnl1 1 0.01 0.71 0
52 INT352842 Binding of Lin28a and Mirlet7a-1 1 0.03 0 0
53 INT311388 Mbnl1 Positive_regulation of Binding of Celf1 1 0.26 0.13 0
54 INT285641 Zfp36 Negative_regulation of Egr1 1 0.06 0.28 0
55 INT277310 Binding of Tnnt2 and Mbnl1 1 0.18 1.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cytoplasmic stress granule. They are ordered first by their pain relevance and then by number of times they were reported in cytoplasmic stress granule. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT44888 Phosphorylation of EIF2S1 12 0.80 5.7 1.7
2 INT113514 Positive_regulation of Eif2s1 2 0.49 0.85 1.46
3 INT235157 Gene_expression of Atxn2 3 0.68 6.74 1.23
4 INT460 Negative_regulation of Atxn2 4 0.43 0.85 1.21
5 INT350157 Binding of ATXN2 1 0.33 3.53 1.02
6 INT241404 Gene_expression of Caprin1 3 0.18 1.38 0.77
7 INT295388 Binding of Grb7 1 0.46 1.02 0.58
8 INT272475 Regulation of Mbnl1 15 0.61 5.39 0.56
9 INT255131 Gene_expression of Mbnl1 34 0.77 10.44 0.55
10 INT249339 Gene_expression of MBNL1 4 0.17 3.64 0.53
11 INT275454 Positive_regulation of Atxn2 1 0.50 1.37 0.53
12 INT492 Binding of Atxn2 3 0.48 1.26 0.51
13 INT44899 Positive_regulation of EIF2S1 3 0.45 1.67 0.51
14 INT295376 Localization of Grb7 1 0.71 0.86 0.5
15 INT149643 Binding of Zfp36 2 0.29 0.45 0.49
16 INT157023 Positive_regulation of Phosphorylation of EIF2S1 1 0.67 3.91 0.48
17 INT255113 Positive_regulation of Gene_expression of Mbnl1 15 0.69 3.28 0.47
18 INT130695 Positive_regulation of Phosphorylation of Eif2s1 1 0.49 0.8 0.47
19 INT130692 Positive_regulation of Gene_expression of Eif2s1 1 0.49 0.81 0.47
20 INT130693 Phosphorylation of Eif2s1 1 0.80 0.8 0.47
21 INT255112 Negative_regulation of Mbnl1 22 0.58 8.5 0.45
22 INT130694 Gene_expression of Eif2s1 1 0.65 0.77 0.44
23 INT204827 Positive_regulation of Zfp36 1 0.26 0.33 0.43
24 INT30733 Localization of Atxn2 4 0.55 0.83 0.41
25 INT50884 Binding of MBNL1 3 0.23 0.32 0.37
26 INT339199 Gene_expression of GRB7 1 0.62 1.3 0.36
27 INT44902 Localization of EIF2S1 1 0.28 0.61 0.31
28 INT255132 Positive_regulation of Mbnl1 15 0.54 2.58 0.27
29 INT295382 Gene_expression of Grb7 1 0.73 0.42 0.27
30 INT255123 Localization of Mbnl1 7 0.80 3.76 0.24
31 INT316448 Positive_regulation of Lin28a 1 0.26 0.53 0.24
32 INT339177 Negative_regulation of GRB7 1 0.35 0.64 0.22
33 INT295378 Phosphorylation of Grb7 1 0.78 0.38 0.21
34 INT324778 Binding of Caprin1 1 0.01 0.65 0.19
35 INT295373 Negative_regulation of Localization of Grb7 1 0.41 0.38 0.19
36 INT327283 Negative_regulation of Zfp36 1 0.39 0.5 0.18
37 INT491 Positive_regulation of Binding of Atxn2 1 0.35 0.08 0.17
38 INT178797 Regulation of Caprin1 1 0.02 0.87 0.17
39 INT157022 Negative_regulation of Phosphorylation of EIF2S1 1 0.41 1.34 0.17
40 INT178801 Phosphorylation of Caprin1 1 0.05 0.87 0.16
41 INT199870 Gene_expression of YBX1 1 0.04 0.1 0.14
42 INT277270 Regulation of Regulation of Mbnl1 1 0.45 0.42 0.14
43 INT44889 Binding of EIF2S1 2 0.23 0.35 0.13
44 INT350668 Positive_regulation of Rc3h1 1 0.49 0.79 0.1
45 INT275455 Negative_regulation of Gene_expression of Atxn2 1 0.43 1.07 0.1
46 INT350640 Negative_regulation of Rc3h1 1 0.41 0.73 0.1
47 INT255128 Binding of Mbnl1 13 0.37 4.34 0.09
48 INT44901 Gene_expression of EIF2S1 3 0.40 0.55 0.09
49 INT255099 Regulation of Binding of Mbnl1 1 0.42 0.3 0.09
50 INT44900 Positive_regulation of Gene_expression of EIF2S1 1 0.18 0.16 0.09
51 INT260907 Phosphorylation of Zfp36 1 0.54 0.47 0.08
52 INT295386 Positive_regulation of Grb7 1 0.47 0.15 0.07
53 INT41372 Regulation of Atxn2 1 0.35 0 0.06
54 INT255111 Positive_regulation of Positive_regulation of Mbnl1 1 0.47 0.54 0.05
55 INT295400 Regulation of Binding of Grb7 1 0.43 0.07 0.04
56 INT260911 Regulation of Phosphorylation of Zfp36 1 0.30 0.23 0.04
57 INT295390 Regulation of Phosphorylation of Grb7 1 0.43 0.07 0.04
58 INT295385 Positive_regulation of Transcription of Grb7 1 0.47 0.05 0.03
59 INT309246 Localization of ATXN2 1 0.10 1.45 0.03
60 INT295398 Negative_regulation of Phosphorylation of Grb7 1 0.41 0.06 0.03
61 INT295380 Transcription of Grb7 1 0.65 0.05 0.03
62 INT262691 Positive_regulation of Gene_expression of Caprin1 1 0.08 0.15 0.03
63 INT295377 Positive_regulation of Phosphorylation of Grb7 1 0.66 0.06 0.03
64 INT255096 Regulation of Gene_expression of Mbnl1 2 0.45 0.72 0
65 INT199871 Positive_regulation of YBX1 2 0.03 1.24 0
66 INT260926 Regulation of Zfp36 2 0.21 0.47 0
67 INT295367 Negative_regulation of Transcription of Grb7 1 0.40 0 0
68 INT177549 Binding of Eif2s1 1 0.04 0.73 0
69 INT255130 Positive_regulation of Binding of Mbnl1 1 0.47 0.75 0
70 INT339160 Positive_regulation of Gene_expression of GRB7 1 0.56 0.45 0
71 INT249358 Gene_expression of ATXN2 1 0.37 3.59 0
72 INT311276 Negative_regulation of Gene_expression of Mbnl1 1 0.37 0.32 0
73 INT67596 Regulation of YBX1 1 0.02 0 0
74 INT352833 Binding of Lin28a 1 0.19 0.54 0
75 INT235147 Negative_regulation of Localization of Atxn2 1 0.31 0.46 0
76 INT277262 Protein_catabolism of Mbnl1 1 0.88 0.11 0
77 INT311342 Positive_regulation of Negative_regulation of Mbnl1 1 0.30 0.26 0
78 INT311291 Regulation of MBNL1 1 0.02 0.69 0
79 INT149645 Positive_regulation of Gene_expression of Zfp36 1 0.14 0 0
80 INT277281 Positive_regulation of Regulation of Mbnl1 1 0.50 0.16 0
81 INT255104 Positive_regulation of Localization of Mbnl1 1 0.47 0 0
82 INT255094 Negative_regulation of Positive_regulation of Mbnl1 1 0.40 0 0
83 INT249344 Positive_regulation of MBNL1 1 0.01 2.88 0
84 INT341298 Regulation of Gene_expression of MBNL1 1 0.11 0 0
85 INT149639 Gene_expression of Zfp36 1 0.22 0 0
86 INT255098 Regulation of Negative_regulation of Mbnl1 1 0.25 0 0
87 INT189632 Negative_regulation of MBNL1 1 0.18 0.29 0
88 INT199872 Binding of YBX1 1 0.02 0.46 0
89 INT272487 Transcription of Mbnl1 1 0.54 0.48 0
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