GO:0010508

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Name positive regulation of autophagy
Categary Process
Go Slim No
Go Link GO:0010508
Unique Molecular Interactions 92
Total Molecular Interactions 106
Total Single Events 584
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of autophagy. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of autophagy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296787 Tbrs1 Positive_regulation of Gene_expression of Tlr9 1 0.06 1.37 0.78
2 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
3 INT296788 Tlr9 Regulation of Positive_regulation of Il1 1 0.07 1.37 0.77
4 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
5 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
6 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
7 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
8 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
9 INT296795 Binding of Tlr9 and Tlr3 2 0.22 1.29 0.45
10 INT306018 Binding of Tlr4 and Tlr9 1 0.15 0.92 0.27
11 INT288497 Binding of Tlr7 and Tlr9 1 0.21 0.97 0.27
12 INT334256 Binding of Tlr9 and Iars 1 0.02 0.68 0.24
13 INT260440 Negative_regulation of Tlr9 Negative_regulation of Positive_regulation of IFNA1 1 0.03 0.96 0.21
14 INT260436 Positive_regulation of Tlr9 Negative_regulation of Positive_regulation of Tlr7 1 0.14 0.65 0.2
15 INT329068 Tlr9 Positive_regulation of Localization of IFNA1 1 0.03 1.54 0.19
16 INT157275 Binding of PRKAA1 and Adipoq 1 0.01 1.13 0.15
17 INT157273 Adipoq Positive_regulation of PRKAA1 1 0.03 1.16 0.14
18 INT333271 Tlr9 Positive_regulation of Localization of Ccl20 1 0.24 0.16 0.14
19 INT326385 Mtdh Regulation of Gdnf 1 0.00 0.41 0.14
20 INT278397 Hps5 Positive_regulation of Tlr9 1 0.15 0.21 0.11
21 INT157264 PPARA Positive_regulation of PRKAA1 1 0.03 0.92 0.08
22 INT157271 Adipor1 Positive_regulation of PRKAA1 1 0.01 0.89 0.08
23 INT193694 IgG2a Positive_regulation of Tlr9 1 0.05 0.07 0.08
24 INT253377 Lep Negative_regulation of Phosphorylation of Prkaa2 1 0.24 1.24 0.06
25 INT260435 Binding of Tlr9 and Tlr7 1 0.09 0.71 0.05
26 INT290165 Tlr9 Positive_regulation of Gene_expression of IFNA1 1 0.10 1.2 0.04
27 INT253413 ATIC Positive_regulation of Gene_expression of Prkaa2 1 0.02 0 0.04
28 INT253417 ATIC Positive_regulation of Prkaa2 1 0.02 0.31 0.04
29 INT290161 Tlr9 Positive_regulation of Gene_expression of Pdc 1 0.21 1.2 0.04
30 INT253363 Lep Regulation of Prkaa2 1 0.15 0.08 0.04
31 INT341021 Positive_regulation of Cp Positive_regulation of Positive_regulation of PIK3CB 1 0.00 0.15 0.04
32 INT253365 Il6 Negative_regulation of Prkaa2 1 0.23 0 0.04
33 INT228591 Adipoq Positive_regulation of Phosphorylation of Prkaa2 1 0.31 0.61 0.04
34 INT341016 Reln Positive_regulation of Positive_regulation of PIK3CB 1 0.01 0.15 0.04
35 INT253415 ATIC Regulation of Phosphorylation of Prkaa2 1 0.03 0 0.03
36 INT253418 ATIC Regulation of Prkaa2 1 0.02 0 0.03
37 INT253370 Lep Negative_regulation of Prkaa2 1 0.29 0.18 0.03
38 INT342733 Gene_expression of Lrrk2 Positive_regulation of Apaf1 1 0.10 0.74 0.03
39 INT250665 EGFR Positive_regulation of PIK3CB 1 0.21 1.39 0
40 INT253359 Positive_regulation of Prkaa2 Negative_regulation of Mtor 1 0.26 0.27 0
41 INT250659 Negative_regulation of PTEN Positive_regulation of Positive_regulation of PIK3CB 1 0.02 1.18 0
42 INT331238 Binding of ULK1 and Pik3r1 1 0.09 0.48 0
43 INT253368 Positive_regulation of Lep Positive_regulation of Prkaa2 1 0.26 0.19 0
44 INT340927 Negative_regulation of PIK3CB Negative_regulation of Positive_regulation of AKT1 1 0.00 0 0
45 INT341025 PIK3CB Positive_regulation of Regulation of Vim 1 0.01 0 0
46 INT271101 PIK3CB Regulation of Akt1 1 0.01 0.72 0
47 INT253382 Il6 Positive_regulation of Prkaa2 1 0.42 0.19 0
48 INT340929 VLDLR Positive_regulation of PIK3CB 1 0.01 0.06 0
49 INT253361 Il6 Negative_regulation of Phosphorylation of Prkaa2 1 0.26 0.16 0
50 INT330226 Positive_regulation of Prkaa2 Positive_regulation of Trib3 1 0.00 0.07 0
51 INT250666 ERBB2 Positive_regulation of PIK3CB 1 0.15 0.69 0
52 INT341020 PIK3CB Regulation of Gene_expression of Fabp7 1 0.02 0 0
53 INT253369 Prkaa2 Negative_regulation of Mtor 1 0.24 0.27 0
54 INT250718 PIK3CB Regulation of Gene_expression of Birc5 1 0.23 0.91 0
55 INT330225 Binding of Tmprss5 and Positive_regulation of Positive_regulation of Prkaa2 1 0.01 0.18 0
56 INT340924 PIK3CB Negative_regulation of Positive_regulation of AKT1 1 0.00 0 0
57 INT330224 Tmprss5 Positive_regulation of Prkaa2 1 0.01 0 0
58 INT294828 DPYD Positive_regulation of PIK3CB 1 0.00 0.51 0
59 INT253379 Lep Positive_regulation of Prkaa2 1 0.39 0.19 0
60 INT341023 PIK3CB Positive_regulation of Nrg1 1 0.03 0.06 0
61 INT253373 Binding of Mtor and Prkaa2 1 0.20 0.26 0
62 INT347290 Positive_regulation of CCL16 Positive_regulation of PIK3CB 1 0.03 0.57 0
63 INT253372 Prkaa2 Regulation of Mtor 1 0.13 0.09 0
64 INT253381 Il6 Regulation of Prkaa2 1 0.16 0 0
65 INT250664 PIK3CB Positive_regulation of AKT1 1 0.09 0.62 0
66 INT250660 PIK3CB Negative_regulation of AKT1 1 0.09 0.83 0
67 INT324814 Binding of Ighm and Tlr9 1 0.06 0.17 0
68 INT303338 Binding of ULK1 and Atg13 1 0.07 0.73 0
69 INT341022 PIK3CB Regulation of Gene_expression of Erbb3 1 0.01 0 0
70 INT330223 Binding of Tmprss5 and Positive_regulation of Prkaa2 1 0.01 0.18 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of autophagy. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of autophagy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149985 Gene_expression of Tlr9 32 0.75 29.83 11.86
2 INT207892 Binding of Tlr9 35 0.46 26.66 6.61
3 INT188672 Positive_regulation of Tlr9 15 0.67 13.1 4.48
4 INT149986 Positive_regulation of Gene_expression of Tlr9 5 0.67 8.18 4.15
5 INT260424 Negative_regulation of Tlr9 8 0.41 8.19 2.92
6 INT250707 Gene_expression of PIK3CB 15 0.31 5.4 1.34
7 INT151567 Gene_expression of Tlr9 6 0.72 3.63 1.26
8 INT71747 Positive_regulation of Prkaa2 19 0.46 8.76 0.98
9 INT250708 Negative_regulation of PIK3CB 17 0.30 3.09 0.94
10 INT331594 Localization of Tlr9 1 0.41 1.66 0.71
11 INT331595 Positive_regulation of Localization of Tlr9 1 0.28 1.66 0.71
12 INT296782 Phosphorylation of Tlr9 1 0.61 0.53 0.63
13 INT288490 Binding of Tlr9 1 0.25 1.88 0.51
14 INT228570 Phosphorylation of Prkaa2 24 0.61 7.9 0.5
15 INT188677 Positive_regulation of Positive_regulation of Tlr9 2 0.29 1.22 0.49
16 INT284455 Regulation of Gene_expression of Tlr9 1 0.30 1.19 0.37
17 INT71752 Negative_regulation of Prkaa2 17 0.39 2.81 0.3
18 INT71750 Regulation of Prkaa2 12 0.41 2.98 0.29
19 INT226115 Positive_regulation of PRKAA1 2 0.15 0.45 0.29
20 INT329061 Positive_regulation of Tlr9 1 0.47 2.05 0.29
21 INT331590 Negative_regulation of Binding of Tlr9 1 0.24 1.52 0.28
22 INT236357 Negative_regulation of Positive_regulation of Tlr9 2 0.33 3.1 0.27
23 INT250712 Regulation of PIK3CB 2 0.15 0.88 0.25
24 INT187504 Gene_expression of Prkaa2 5 0.65 1.3 0.22
25 INT253395 Negative_regulation of Phosphorylation of Prkaa2 9 0.39 1.35 0.2
26 INT178118 Positive_regulation of PIK3CB 12 0.32 5.06 0.19
27 INT333222 Gene_expression of Mtdh 1 0.01 1.44 0.17
28 INT333226 Negative_regulation of Gene_expression of Mtdh 1 0.00 1.44 0.17
29 INT253401 Positive_regulation of Positive_regulation of Prkaa2 2 0.33 1.39 0.15
30 INT151569 Transcription of Tlr9 3 0.69 0.75 0.11
31 INT151566 Positive_regulation of Transcription of Tlr9 2 0.47 0.67 0.11
32 INT187495 Positive_regulation of Gene_expression of Prkaa2 1 0.49 0.09 0.11
33 INT253404 Positive_regulation of Phosphorylation of Prkaa2 3 0.29 1.23 0.09
34 INT253390 Negative_regulation of Positive_regulation of Prkaa2 4 0.28 0.76 0.08
35 INT253387 Negative_regulation of Regulation of Prkaa2 1 0.28 0.08 0.05
36 INT342721 Localization of Lrrk2 1 0.39 0.67 0.04
37 INT342722 Gene_expression of Lrrk2 2 0.41 1.81 0.03
38 INT250703 Negative_regulation of Negative_regulation of PIK3CB 2 0.20 1.16 0.03
39 INT342711 Positive_regulation of Gene_expression of Lrrk2 1 0.36 0.73 0.03
40 INT250702 Positive_regulation of Gene_expression of PIK3CB 3 0.23 1.79 0
41 INT347315 Binding of PIK3CB 2 0.19 1.57 0
42 INT253402 Binding of Prkaa2 2 0.24 0.43 0
43 INT340980 Negative_regulation of Positive_regulation of PIK3CB 2 0.12 0.59 0
44 INT322525 Phosphorylation of PIK3CB 2 0.42 1.09 0
45 INT303325 Negative_regulation of ULK1 1 0.14 0.81 0
46 INT253408 Positive_regulation of Negative_regulation of Prkaa2 1 0.33 0.44 0
47 INT333235 Negative_regulation of Protein_catabolism of Mtdh 1 0.00 1.31 0
48 INT330234 Localization of Prkaa2 1 0.21 0 0
49 INT303323 Regulation of ULK1 1 0.13 0.09 0
50 INT161253 Regulation of Gene_expression of Tlr9 1 0.09 0.18 0
51 INT340989 Localization of PIK3CB 1 0.06 0 0
52 INT253394 Negative_regulation of Negative_regulation of Prkaa2 1 0.28 0.33 0
53 INT333219 Protein_catabolism of Mtdh 1 0.01 1.31 0
54 INT324755 Positive_regulation of Binding of Tlr9 1 0.26 0.17 0
55 INT161254 Regulation of Tlr9 1 0.09 0.18 0
56 INT271099 Regulation of Gene_expression of PIK3CB 1 0.08 0.62 0
57 INT322533 Negative_regulation of Gene_expression of PIK3CB 1 0.11 0.57 0
58 INT329056 Positive_regulation of Gene_expression of Tlr9 1 0.43 0.09 0
59 INT340998 Positive_regulation of Positive_regulation of PIK3CB 1 0.04 0.14 0
60 INT151568 Negative_regulation of Transcription of Tlr9 1 0.41 0.08 0
61 INT322530 Negative_regulation of Phosphorylation of PIK3CB 1 0.15 0.24 0
62 INT322527 Regulation of Negative_regulation of PIK3CB 1 0.07 0 0
63 INT341498 Negative_regulation of Gene_expression of Tlr9 1 0.11 0.38 0
64 INT238857 Phosphorylation of PRKAA1 1 0.01 1.73 0
65 INT333231 Negative_regulation of Mtdh 1 0.00 1.25 0
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