GO:0010512

From wiki-pain
Jump to: navigation, search
Name negative regulation of phosphatidylinositol biosynthetic process
Categary Process
Go Slim No
Go Link GO:0010512
Unique Molecular Interactions 99
Total Molecular Interactions 122
Total Single Events 672
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of phosphatidylinositol biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of phosphatidylinositol biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
2 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
3 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91
4 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 2 0.00 0.95 0.46
5 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
6 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3
7 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
8 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29
9 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29
10 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
11 INT224457 TNF Positive_regulation of Pdgfa 1 0.34 1.22 0.27
12 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25
13 INT193035 Positive_regulation of PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
14 INT193025 PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
15 INT193036 EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
16 INT193032 Positive_regulation of EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
17 INT332245 Pdgfa Positive_regulation of Stat6 1 0.07 1.22 0.19
18 INT355733 Pdgfb Regulation of Transcription of Bdnf 1 0.10 0.86 0.19
19 INT192333 PDGFA Positive_regulation of Gene_expression of FN1 2 0.11 1.26 0.18
20 INT355732 Pdgfb Negative_regulation of Bdnf 1 0.13 0.87 0.17
21 INT202312 PDGFB Positive_regulation of Gene_expression of Col7a1 1 0.01 0.7 0.16
22 INT202311 PDGFB Positive_regulation of Gene_expression of Fn1 1 0.02 0.7 0.16
23 INT298717 Fgf2 Positive_regulation of Gene_expression of PDGFA 1 0.01 0.23 0.15
24 INT298716 Ngf Positive_regulation of Gene_expression of PDGFA 1 0.01 0.22 0.15
25 INT238331 PDGFA Regulation of Gene_expression of GOPC 1 0.04 0 0.14
26 INT238330 Binding of PDGFA and Regulation of Gene_expression of GOPC 1 0.06 0 0.14
27 INT332254 Pdgfa Positive_regulation of Stat3 1 0.02 0.52 0.14
28 INT238333 Binding of PDGFA and Regulation of Gene_expression of ADAMTS1 1 0.06 0 0.14
29 INT286900 Binding of HBM and PDGFA 1 0.04 1.08 0.14
30 INT155687 PDGFA Positive_regulation of Phosphorylation of FBRS 1 0.01 0.43 0.14
31 INT332256 Pdgfa Positive_regulation of SOAT1 1 0.01 0.51 0.14
32 INT332243 Pdgfa Positive_regulation of Stat1 1 0.06 0.52 0.14
33 INT238336 PDGFA Regulation of Negative_regulation of ADAMTS5 1 0.04 0 0.14
34 INT298715 Igf1 Positive_regulation of Gene_expression of PDGFA 1 0.00 0.22 0.14
35 INT223084 Binding of Pdgfa and Pdgfb 2 0.17 0.83 0.13
36 INT225024 PDGFB Positive_regulation of Gene_expression of Cxcl5 1 0.16 0.08 0.13
37 INT261789 PDGFA Positive_regulation of Slc12a5 1 0.07 0.15 0.12
38 INT332250 Stat6 Positive_regulation of Gene_expression of Pdgfa 1 0.05 1.33 0.12
39 INT263429 Pdgfb Positive_regulation of Localization of Abl1 1 0.01 0 0.12
40 INT224455 Pdgfa Regulation of VEGFA 1 0.07 0.22 0.11
41 INT48194 Pdgfb Positive_regulation of Setd1a 1 0.23 0 0.09
42 INT347302 PDGFA Positive_regulation of ITK 1 0.04 1.4 0.09
43 INT251777 Negative_regulation of TXK Positive_regulation of PDGFA 1 0.04 1 0.08
44 INT251773 TXK Positive_regulation of PDGFA 1 0.04 1 0.08
45 INT179346 Pdgfa Positive_regulation of Positive_regulation of Mapk3 1 0.05 0.71 0.07
46 INT223085 Binding of Pdgfb and Insrr 1 0.01 0.91 0.07
47 INT88411 Positive_regulation of PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
48 INT231440 PDGFA Positive_regulation of Gene_expression of HGF 1 0.16 0.83 0.07
49 INT231434 FN1 Positive_regulation of Gene_expression of PDGFA 1 0.04 0.83 0.07
50 INT246539 EGF Negative_regulation of Gene_expression of PDGFA 1 0.06 0.38 0.07
51 INT88408 PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
52 INT246538 PDGFA Negative_regulation of Gene_expression of EGF 1 0.06 0.38 0.07
53 INT179345 Pdgfa Positive_regulation of Mapk3 1 0.05 0.71 0.07
54 INT231441 PDGFA Positive_regulation of Gene_expression of VEGFA 1 0.17 0.83 0.07
55 INT279280 Binding of PDGFA and PDGFB 1 0.06 0.9 0.06
56 INT343477 Epo Positive_regulation of Pdgfb 1 0.11 0.31 0.06
57 INT225023 PDGFB Regulation of Transcription of Ccl21 1 0.11 0 0.06
58 INT94852 PDGFB Regulation of Gene_expression of COL7A1 1 0.09 0.06 0.06
59 INT279291 PDGFA Positive_regulation of PDGFRB 1 0.16 1.02 0.06
60 INT279275 PDGFA Positive_regulation of TXK 1 0.05 1.02 0.06
61 INT279276 PDGFA Positive_regulation of NCOR2 1 0.00 1.02 0.06
62 INT225022 PDGFB Regulation of Ccl21 1 0.11 0 0.06
63 INT343471 Epo Positive_regulation of Gene_expression of Pdgfb 1 0.11 0.31 0.06
64 INT244641 PDGFA Regulation of MTOR 1 0.07 2.55 0.06
65 INT202310 Binding of PDGFB and Pdgfrb 1 0.11 0.39 0.04
66 INT263427 Pdgfb Positive_regulation of Phosphorylation of Rock1 1 0.00 0 0.04
67 INT223086 Binding of Pdgfb and Pdgfrb 1 0.33 0.46 0.04
68 INT179348 Pdgfa Positive_regulation of Binding of Pscs 1 0.04 0.38 0.03
69 INT179347 Pdgfa Positive_regulation of Pscs 1 0.04 0.38 0.03
70 INT279288 PDGFB Positive_regulation of NCOR2 1 0.00 0.52 0.03
71 INT279285 PDGFB Positive_regulation of TXK 1 0.05 0.52 0.03
72 INT288134 Pdgfa Regulation of Ifi35 1 0.01 0.78 0.03
73 INT313618 Binding of Acly and Pdgfb 1 0.00 0.18 0.03
74 INT328408 Nlrp1a Positive_regulation of Pdgfb 1 0.07 0.74 0.03
75 INT179344 Pdgfa Positive_regulation of Binding of Jun 1 0.00 0.38 0.03
76 INT354835 Binding of VEGFA and Pdgfa 1 0.00 1.5 0.03
77 INT279277 PDGFB Positive_regulation of PDGFRB 1 0.14 0.52 0.03
78 INT347304 PDGFA Positive_regulation of Gene_expression of AKT1 1 0.19 0.6 0
79 INT352995 IPMK Regulation of PDGFA 1 0.00 0.66 0
80 INT315868 Vhl Positive_regulation of Transcription of PDGFA 1 0.00 1.39 0
81 INT192328 UBR7 Regulation of Phosphorylation of PDGFA 1 0.00 0 0
82 INT315856 FLT3 Positive_regulation of Gene_expression of PDGFA 1 0.01 1.15 0
83 INT328411 Nlrp1a Negative_regulation of Pdgfb 1 0.08 0.39 0
84 INT224993 INCENP Regulation of PDGFB 1 0.00 0 0
85 INT194362 PDGFA Regulation of EGFR 1 0.23 1.56 0
86 INT223083 Gene_expression of Pdgfb Positive_regulation of Cm3 1 0.02 1 0
87 INT347296 PDGFA Positive_regulation of CCL16 1 0.06 0.6 0
88 INT225020 Binding of PDGFB and Mtpn 1 0.01 0.15 0
89 INT277703 Binding of Pdgfrb and Pdgfb 1 0.02 0.23 0
90 INT286902 Binding of PDGFA and VEGFA 1 0.24 1.1 0
91 INT198002 KDR Negative_regulation of PDGFA 1 0.09 0.94 0
92 INT193307 Binding of PDGFA and PRNP 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of phosphatidylinositol biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of phosphatidylinositol biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46
2 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
3 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
4 INT96778 Positive_regulation of Pdgfa 22 0.46 12.7 5.31
5 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
6 INT96776 Positive_regulation of Gene_expression of Pdgfa 8 0.40 7.79 3.93
7 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
8 INT96777 Localization of Pdgfa 12 0.79 5.86 3.52
9 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
10 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
11 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
12 INT271599 Phosphorylation of Pdgfa 1 0.11 2.55 2.81
13 INT172963 Negative_regulation of Pdgfa 11 0.21 12.94 2.64
14 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
15 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
16 INT223080 Binding of Pdgfa 8 0.18 7.21 2.44
17 INT74528 Negative_regulation of PDGFB 11 0.40 10.34 1.48
18 INT74530 Transcription of PDGFB 7 0.65 4.56 1.47
19 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
20 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29
21 INT192349 Negative_regulation of Gene_expression of PDGFB 5 0.31 2.64 1.25
22 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17
23 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12
24 INT96774 Positive_regulation of Localization of Pdgfa 3 0.69 1.21 0.95
25 INT188317 Positive_regulation of Gene_expression of PDGFA 15 0.46 12.7 0.91
26 INT271598 Negative_regulation of Phosphorylation of Pdgfa 1 0.05 0.77 0.88
27 INT271597 Regulation of Gene_expression of Pdgfa 1 0.05 0.81 0.87
28 INT171096 Transcription of PDGFA 5 0.47 4.42 0.79
29 INT95118 Negative_regulation of Gene_expression of PDGFA 4 0.54 5.03 0.76
30 INT202307 Regulation of Gene_expression of PDGFB 2 0.26 1.24 0.71
31 INT210390 Binding of PDGFA 12 0.36 6.78 0.63
32 INT74529 Binding of PDGFB 13 0.36 7.41 0.62
33 INT277699 Gene_expression of Pdgfb 5 0.20 4.84 0.59
34 INT202306 Negative_regulation of Localization of PDGFB 2 0.25 0.76 0.55
35 INT198048 Protein_catabolism of PDGFA 2 0.28 2.05 0.5
36 INT224442 Negative_regulation of Gene_expression of Pdgfa 2 0.30 2.48 0.5
37 INT343801 Negative_regulation of Transcription of PDGFA 1 0.29 0.37 0.5
38 INT202309 Regulation of Localization of PDGFB 1 0.36 0.92 0.49
39 INT223081 Negative_regulation of Gene_expression of Pdgfb 2 0.37 3.07 0.47
40 INT313617 Positive_regulation of Pdgfb 4 0.35 1.53 0.46
41 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42
42 INT76143 Positive_regulation of Regulation of PDGFB 1 0.01 0.08 0.4
43 INT74532 Positive_regulation of Transcription of PDGFB 1 0.57 0.73 0.4
44 INT317875 Binding of Pdgfb 3 0.10 1.15 0.36
45 INT153261 Positive_regulation of Localization of PDGFB 2 0.37 1.98 0.36
46 INT332231 Positive_regulation of Positive_regulation of Pdgfa 1 0.16 0.83 0.31
47 INT192346 Positive_regulation of Localization of PDGFA 5 0.37 1.52 0.29
48 INT224441 Negative_regulation of Pdgfb 2 0.33 1.61 0.27
49 INT349702 Positive_regulation of Transcription of Pdgfb 1 0.35 0 0.23
50 INT277701 Localization of Pdgfb 3 0.23 1.49 0.22
51 INT333364 Negative_regulation of Positive_regulation of Pdgfa 1 0.03 0.99 0.22
52 INT349701 Transcription of Pdgfb 1 0.40 0 0.22
53 INT332238 Regulation of Regulation of Pdgfa 1 0.14 0.94 0.16
54 INT205603 Regulation of Pdgfa 5 0.16 4.84 0.15
55 INT155694 Phosphorylation of PDGFA 2 0.58 0.42 0.13
56 INT210396 Negative_regulation of Binding of PDGFA 1 0.02 1.6 0.13
57 INT225004 Regulation of Positive_regulation of PDGFB 1 0.26 0.1 0.13
58 INT278037 Positive_regulation of Transcription of PDGFA 4 0.07 2.39 0.12
59 INT319408 Negative_regulation of Binding of PDGFB 1 0.15 0.89 0.09
60 INT355724 Negative_regulation of Positive_regulation of Pdgfb 1 0.13 0.6 0.07
61 INT319411 Negative_regulation of Transcription of PDGFB 1 0.15 1.03 0.07
62 INT277702 Positive_regulation of Gene_expression of Pdgfb 2 0.10 0.55 0.05
63 INT286904 Regulation of Binding of PDGFA 1 0.30 0.74 0.04
64 INT225003 Positive_regulation of Binding of PDGFB 1 0.29 0 0.03
65 INT202308 Phosphorylation of PDGFB 1 0.34 0.43 0.03
66 INT223077 Regulation of Pdgfb 1 0.23 0.34 0
67 INT292120 Regulation of Regulation of PDGFA 1 0.12 0.93 0
68 INT343453 Phosphorylation of Pdgfb 1 0.13 0.1 0
69 INT277700 Binding of Pdgfb 1 0.09 0.67 0
70 INT347305 Negative_regulation of Positive_regulation of PDGFA 1 0.17 0.56 0
71 INT277696 Regulation of Positive_regulation of Pdgfb 1 0.03 0.52 0
72 INT223079 Regulation of Gene_expression of Pdgfb 1 0.23 1.17 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox