GO:0010572

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Name positive regulation of platelet activation
Categary Process
Go Slim No
Go Link GO:0010572
Unique Molecular Interactions 587
Total Molecular Interactions 895
Total Single Events 5228
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of platelet activation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of platelet activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
5 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
6 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
7 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
8 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
9 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
10 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
11 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
12 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
13 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
14 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
15 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
16 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
17 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
18 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
19 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
20 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
21 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
22 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
23 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
24 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
25 INT101317 Binding of Selplg and Selp 1 0.02 3.72 1.01
26 INT124918 Binding of PLEK and Maob 1 0.10 1.05 0.98
27 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
28 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
29 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
30 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
31 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
32 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
33 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
34 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
35 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
36 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
37 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
38 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
39 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
40 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
41 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
42 INT284306 Tlr4 Positive_regulation of Adrb3 1 0.00 1.19 0.74
43 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
44 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
45 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71
46 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
47 INT81968 Binding of PLEK and Adra2a 1 0.07 0.1 0.7
48 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
49 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69
50 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
51 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
52 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66
53 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
54 INT74729 Binding of Mpz and Ptprj 1 0.06 0.15 0.66
55 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
56 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64
57 INT121713 WAS Positive_regulation of Gene_expression of SELP 1 0.30 0.49 0.63
58 INT339393 Tlr4 Positive_regulation of Nfkb1 1 0.24 2.06 0.61
59 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6
60 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6
61 INT140264 Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
62 INT140263 Negative_regulation of Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
63 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59
64 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57
65 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
66 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57
67 INT306330 Cd14 Positive_regulation of Gene_expression of Tlr4 1 0.48 0.54 0.57
68 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56
69 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
70 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56
71 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56
72 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
73 INT243056 Binding of LBP and Tlr4 1 0.00 1.11 0.55
74 INT310767 Tlr4 Regulation of Gene_expression of S100a8 1 0.02 0.7 0.54
75 INT210934 Gene_expression of Tlr4 Negative_regulation of Ccl2 1 0.47 0.69 0.54
76 INT354367 Binding of FGFR1 and Tlr4 1 0.01 1.23 0.53
77 INT187101 Selp Regulation of Sele 1 0.20 1.23 0.53
78 INT179503 Cd14 Regulation of Positive_regulation of Tlr4 1 0.38 0.58 0.52
79 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
80 INT285911 Binding of TLR4 and Cd14 1 0.05 1.13 0.51
81 INT324523 Tlr4 Regulation of Gene_expression of PGE 1 0.23 1.98 0.51
82 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49
83 INT306019 Binding of Tlr4 and LY96 1 0.06 0.91 0.49
84 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49
85 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48
86 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48
87 INT322264 Binding of MPZ and TLR4 1 0.18 1.68 0.47
88 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47
89 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47
90 INT284300 Tlr4 Positive_regulation of Gene_expression of Mir155 1 0.18 0.91 0.47
91 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46
92 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46
93 INT233508 Tlr4 Regulation of Gene_expression of Gpr18 1 0.04 0.45 0.46
94 INT96103 Binding of PPBP and Selp 1 0.00 1.22 0.46
95 INT310769 Pam Regulation of Tlr4 1 0.01 0.69 0.46
96 INT96083 Binding of PPBP and SELP 1 0.02 1.21 0.46
97 INT96095 Binding of Selp and Pf4 1 0.01 1.2 0.45
98 INT96097 Binding of SELP and Pf4 1 0.13 1.2 0.45
99 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44
100 INT212810 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.03 0.74 0.43
101 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
102 INT308696 Binding of Tlr4 and Tlr4 1 0.00 0.34 0.42
103 INT336926 Mir341 Regulation of Tlr4 1 0.02 1.57 0.41
104 INT52954 Binding of Pdpn and Flvcr2 1 0.05 0.42 0.41
105 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4
106 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
107 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39
108 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39
109 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39
110 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
111 INT81300 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.02 0.38 0.39
112 INT310697 Tlr4 Positive_regulation of Gene_expression of Ptger2 2 0.03 1.34 0.38
113 INT339504 Binding of Irak1 and Tlr4 1 0.08 0.12 0.38
114 INT204893 Regulation of Tlr4 Positive_regulation of gr 1 0.11 0.9 0.38
115 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38
116 INT147969 Binding of Ly86 and Tlr4 1 0.30 0.37 0.38
117 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38
118 INT310600 Tbxa2r Positive_regulation of PLEK 1 0.53 0.45 0.38
119 INT139566 Binding of PLEK and Tbxa2r 1 0.01 1.14 0.38
120 INT215275 Tlr4 Positive_regulation of Gene_expression of Ros1 1 0.01 1.37 0.38
121 INT339511 Binding of Tlr4 and Traf6 1 0.05 0.12 0.38
122 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 0.05 0.17 0.38
123 INT188560 Negative_regulation of Binding of IRF6 and TLR4 1 0.04 0.58 0.38
124 INT204905 Tlr4 Positive_regulation of gr 1 0.18 0.9 0.38
125 INT216709 Binding of SELP and PSMG1 3 0.08 1.48 0.37
126 INT324821 Tlr4 Positive_regulation of Gene_expression of Maob 1 0.07 0.44 0.37
127 INT324813 Tlr4 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
128 INT100091 Tlr4 Regulation of Localization of Tnf 1 0.01 0.42 0.37
129 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
130 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
131 INT110135 Tlr4 Regulation of Localization of Gnrh1 1 0.01 0.2 0.36
132 INT324808 Tlr4 Positive_regulation of Bad 1 0.02 0.43 0.36
133 INT337304 PTAFR Positive_regulation of Gene_expression of TLR4 1 0.62 1.99 0.36
134 INT188563 TLR4 Positive_regulation of Gene_expression of PRF1 1 0.03 0.78 0.36
135 INT99015 Binding of Selp and Vcam1 2 0.27 1.76 0.35
136 INT118743 Tlr4 Positive_regulation of Itgam 1 0.39 0.41 0.35
137 INT110132 Tlr4 Regulation of Localization of LH 1 0.01 0.2 0.35
138 INT114809 Selp Positive_regulation of Gene_expression of F3 1 0.00 0.88 0.34
139 INT139974 Adp Positive_regulation of Gene_expression of Selp 1 0.00 1.79 0.34
140 INT244324 Csf2 Positive_regulation of Tlr4 1 0.23 0.95 0.34
141 INT110134 Tlr4 Regulation of Regulation of Gnrh1 1 0.01 0.15 0.33
142 INT224691 Positive_regulation of Tlr4 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33
143 INT322045 Gp6 Positive_regulation of Gene_expression of Selp 1 0.04 0.15 0.33
144 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32
145 INT253766 Binding of Apex1 and Tlr4 1 0.03 0.53 0.32
146 INT295198 Tlr4 Positive_regulation of Gene_expression of Ptger2 1 0.01 0.15 0.32
147 INT322016 Binding of IL1B and TLR4 1 0.05 0.18 0.32
148 INT222441 Tlr4 Positive_regulation of Gene_expression of Tac1 1 0.00 0.39 0.32
149 INT276604 Tlr4 Positive_regulation of Gene_expression of Paf 1 0.22 0.37 0.31
150 INT276605 Tlr4 Positive_regulation of Gene_expression of Mthfd1 1 0.06 0.37 0.31
151 INT288198 Binding of Tlr4 and Mapk14 1 0.01 0.63 0.31
152 INT185319 Il6 Positive_regulation of Gene_expression of Tlr4 1 0.11 0.36 0.31
153 INT185322 TNF Positive_regulation of Gene_expression of Tlr4 1 0.01 0.36 0.31
154 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
155 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
156 INT306323 Tlr4 Positive_regulation of Ticam1 3 0.25 0.55 0.3
157 INT96096 Binding of Serpinc1 and Selp 1 0.00 0.69 0.3
158 INT324832 Tlr4 Positive_regulation of IFNA1 1 0.05 0.46 0.3
159 INT96102 Binding of TAT and Selp 1 0.04 0.7 0.3
160 INT229600 Tlr4 Positive_regulation of Il1a 1 0.00 0.41 0.3
161 INT223752 Tlr4 Positive_regulation of Il1 1 0.12 0.64 0.3
162 INT178342 Positive_regulation of Tlr4 Positive_regulation of Il6 1 0.13 0.25 0.3
163 INT96082 Binding of SELP and TAT 1 0.40 0.69 0.3
164 INT306319 Cd14 Positive_regulation of Tlr4 1 0.48 0.29 0.3
165 INT168616 Tlr4 Negative_regulation of Localization of Tnf 1 0.33 0.44 0.3
166 INT96100 Binding of SELP and F2 1 0.01 0.67 0.29
167 INT96101 Binding of SELP and Serpinc1 1 0.01 0.69 0.29
168 INT96094 Binding of Selp and F2 1 0.00 0.67 0.29
169 INT354368 FGFR1 Positive_regulation of Tlr4 1 0.01 0.16 0.29
170 INT144862 Tlr4 Positive_regulation of PGE 2 0.13 0.35 0.28
171 INT215274 Tlr4 Positive_regulation of Ros1 2 0.02 1.48 0.28
172 INT310696 Tlr4 Positive_regulation of Positive_regulation of Cftr 1 0.16 0.74 0.28
173 INT337293 PTAFR Positive_regulation of Positive_regulation of TLR4 1 0.62 1.43 0.28
174 INT339494 Eif2ak2 Positive_regulation of Tlr4 1 0.13 0.18 0.28
175 INT310255 Tlr4 Positive_regulation of Gene_expression of Cd86 2 0.18 0.06 0.27
176 INT343832 Positive_regulation of EDA Positive_regulation of TLR4 1 0.11 0.43 0.27
177 INT295197 Tlr4 Positive_regulation of Ptger2 1 0.01 0.05 0.27
178 INT306018 Binding of Tlr4 and Tlr9 1 0.15 0.92 0.27
179 INT222428 Negative_regulation of Tlr4 Positive_regulation of Il6 1 0.01 0.26 0.27
180 INT222412 Cd14 Negative_regulation of Binding of Tlr4 1 0.02 0.26 0.27
181 INT222440 Tlr4 Positive_regulation of Localization of Pomc 1 0.01 0.35 0.27
182 INT268766 Tlr4 Positive_regulation of Gene_expression of Ccr1 1 0.04 0.4 0.26
183 INT78067 Tlr4 Positive_regulation of Localization of Ptger2 1 0.01 0.07 0.26
184 INT290707 Binding of Tlr4 and Cd200r1 1 0.01 0.7 0.26
185 INT222422 Tlr4 Positive_regulation of Il6 1 0.01 0.25 0.26
186 INT310766 Tlr4 Positive_regulation of Cxcl2 1 0.29 0.28 0.26
187 INT306325 Tlr4 Positive_regulation of Localization of Cd14 1 0.39 0.37 0.26
188 INT128644 Binding of Icam1 and Selp 2 0.39 0.57 0.25
189 INT295200 Hspg2 Positive_regulation of Tlr4 1 0.00 0 0.25
190 INT323612 Negative_regulation of Tlr4 Positive_regulation of Hmgb1 1 0.23 0.2 0.25
191 INT323610 Tlr4 Positive_regulation of Hmgb1 1 0.25 0.2 0.25
192 INT350074 Binding of Tlr4 and Myadm 1 0.00 0.5 0.25
193 INT343864 EDA Positive_regulation of Gene_expression of TLR4 1 0.11 0.44 0.25
194 INT222421 Tlr4 Negative_regulation of Localization of Prl 1 0.02 0.45 0.25
195 INT343931 Hapln1 Negative_regulation of Tlr4 1 0.12 0.42 0.25
196 INT350079 Tlr4 Positive_regulation of Ptger2 1 0.01 0.57 0.25
197 INT321224 TLR4 Positive_regulation of NFKB1 1 0.04 1.02 0.25
198 INT324694 Tlr4 Positive_regulation of Gene_expression of Pnoc 1 0.05 0.56 0.24
199 INT242875 INS Negative_regulation of Gene_expression of TLR4 1 0.11 1.41 0.24
200 INT221383 Tlr4 Positive_regulation of Localization of Ptger2 1 0.00 1.78 0.23

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of platelet activation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of platelet activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
2 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
3 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
4 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03
5 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
6 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
7 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
8 INT9296 Negative_regulation of PLEK 100 0.57 36.65 27.52
9 INT49141 Gene_expression of Selp 157 0.78 85.22 24.78
10 INT134651 Binding of TLR4 89 0.48 66.96 23.19
11 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
12 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
13 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
14 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
15 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
16 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
17 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
18 INT71510 Positive_regulation of Selp 47 0.68 30.43 12.8
19 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47
20 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64
21 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
22 INT18412 Binding of PLEK 49 0.47 17.82 10.72
23 INT3366 Localization of PLEK 44 0.78 15.83 9.55
24 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
25 INT10969 Positive_regulation of PLEK 33 0.67 16.96 8.35
26 INT12975 Regulation of PLEK 21 0.60 13.62 8.28
27 INT51458 Negative_regulation of Gene_expression of Selp 29 0.57 12.64 8.1
28 INT67424 Positive_regulation of Gene_expression of Selp 36 0.68 17.08 7.95
29 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
30 INT63169 Positive_regulation of Gene_expression of Selp 35 0.69 21.95 7.16
31 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
32 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
33 INT63170 Positive_regulation of Selp 27 0.68 24.1 6.3
34 INT97797 Localization of TLR4 18 0.77 13.78 6
35 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
36 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
37 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
38 INT49801 Positive_regulation of SELP 21 0.48 21.34 5.25
39 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
40 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
41 INT52952 Binding of Pdpn 8 0.13 3.57 4.79
42 INT99001 Negative_regulation of Selp 23 0.59 16.68 4.74
43 INT61036 Negative_regulation of Selp 12 0.50 7.45 4.46
44 INT117551 Regulation of Gene_expression of Selp 15 0.44 7.32 4.2
45 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
46 INT67423 Regulation of Gene_expression of Selp 16 0.60 7.4 3.68
47 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
48 INT73802 Regulation of Selp 17 0.60 8.72 3.51
49 INT63425 Positive_regulation of Gene_expression of SELP 23 0.67 15.34 3.48
50 INT130557 Negative_regulation of Gene_expression of Selp 17 0.54 6.56 3.45
51 INT76501 Binding of Selp 16 0.41 8.51 3.4
52 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
53 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
54 INT59719 Localization of SELP 12 0.78 8.4 2.95
55 INT185315 Transcription of Tlr4 24 0.69 8.65 2.93
56 INT28891 Localization of Selp 13 0.60 8.23 2.83
57 INT156579 Localization of Selp 14 0.73 6.53 2.69
58 INT100086 Negative_regulation of Localization of Tlr4 15 0.37 5.92 2.47
59 INT30001 Negative_regulation of Gene_expression of PLEK 8 0.57 3.31 2.47
60 INT96084 Binding of Selp 12 0.48 8.41 2.16
61 INT222609 Binding of Tlr4 8 0.43 4.03 1.98
62 INT326816 Negative_regulation of Positive_regulation of Tlr4 2 0.59 3.96 1.95
63 INT295469 Localization of Tlr4 3 0.75 2.22 1.88
64 INT301954 Regulation of Negative_regulation of Tlr4 1 0.45 2.46 1.77
65 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74
66 INT33393 Positive_regulation of Gene_expression of PLEK 9 0.67 7.35 1.65
67 INT23176 Gene_expression of Pdpn 6 0.75 4.06 1.65
68 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64
69 INT100549 Negative_regulation of SELP 6 0.43 4.17 1.46
70 INT112562 Binding of SELP 11 0.34 6.25 1.44
71 INT28892 Positive_regulation of Localization of Selp 3 0.35 1.04 1.4
72 INT80086 Regulation of Gene_expression of PLEK 5 0.60 2.79 1.29
73 INT179497 Positive_regulation of Binding of Tlr4 12 0.50 6.49 1.27
74 INT100548 Regulation of SELP 8 0.29 8.56 1.17
75 INT152225 Regulation of Positive_regulation of Tlr4 8 0.53 2.5 1.12
76 INT30002 Negative_regulation of Negative_regulation of PLEK 3 0.42 0.76 1.12
77 INT78050 Positive_regulation of Positive_regulation of Selp 3 0.43 3.63 1.02
78 INT118738 Transcription of Tlr4 4 0.70 1.39 1
79 INT295466 Positive_regulation of Regulation of Tlr4 2 0.44 1.33 0.89
80 INT168278 Positive_regulation of Phosphorylation of Tlr4 1 0.48 1.05 0.88
81 INT168277 Phosphorylation of Tlr4 1 0.78 1.05 0.88
82 INT208243 Positive_regulation of Phosphorylation of Tlr4 5 0.31 3.74 0.86
83 INT81220 Negative_regulation of Binding of PLEK 5 0.42 2.03 0.84
84 INT36881 Regulation of Positive_regulation of PLEK 2 0.44 1.77 0.84
85 INT98994 Regulation of Selp 10 0.45 3.91 0.83
86 INT18413 Positive_regulation of Binding of PLEK 3 0.49 1.06 0.77
87 INT3368 Positive_regulation of Localization of PLEK 3 0.45 0.51 0.77
88 INT188582 Positive_regulation of Transcription of TLR4 2 0.50 4.07 0.77
89 INT295465 Regulation of Positive_regulation of Tlr4 2 0.39 1.28 0.75
90 INT151128 Positive_regulation of Negative_regulation of Tlr4 2 0.46 1 0.75
91 INT67252 Regulation of Pdpn 1 0.00 0.9 0.74
92 INT254115 Negative_regulation of Phosphorylation of Tlr4 5 0.27 3.91 0.71
93 INT161529 Regulation of Gene_expression of Tlr4 3 0.45 2.7 0.69
94 INT186800 Positive_regulation of Binding of TLR4 2 0.47 1.31 0.67
95 INT236785 Regulation of Positive_regulation of TLR4 1 0.32 1.28 0.66
96 INT52951 Negative_regulation of Binding of Pdpn 1 0.16 0.63 0.66
97 INT42121 Negative_regulation of Localization of PLEK 4 0.42 1.92 0.61
98 INT187088 Regulation of Negative_regulation of Selp 1 0.31 1.07 0.61
99 INT157576 Positive_regulation of Localization of Selp 2 0.49 1.19 0.59
100 INT63423 Negative_regulation of Gene_expression of SELP 13 0.55 1.98 0.57
101 INT236786 Positive_regulation of Localization of TLR4 2 0.45 1.89 0.57
102 INT204864 Negative_regulation of Negative_regulation of Tlr4 3 0.30 2.05 0.56
103 INT45916 Regulation of Negative_regulation of PLEK 1 0.44 0 0.54
104 INT3367 Regulation of Localization of PLEK 1 0.44 0.34 0.52
105 INT74724 Regulation of Ptprj 2 0.05 0.35 0.51
106 INT74725 Localization of Ptprj 1 0.14 0.15 0.5
107 INT246926 Negative_regulation of Transcription of Tlr4 3 0.41 1.78 0.49
108 INT343888 Regulation of Regulation of TLR4 1 0.25 1.34 0.49
109 INT202063 Regulation of Binding of TLR4 2 0.44 2.14 0.47
110 INT152229 Positive_regulation of Regulation of Tlr4 2 0.40 0.29 0.46
111 INT182136 Regulation of Regulation of PLEK 1 0.44 0.4 0.44
112 INT136325 Negative_regulation of Binding of Selp 2 0.59 2.26 0.42
113 INT267147 Regulation of Positive_regulation of SELP 2 0.29 3.94 0.42
114 INT185313 Regulation of Transcription of Tlr4 3 0.20 0.49 0.39
115 INT178182 Negative_regulation of Binding of Tlr4 3 0.33 2.13 0.38
116 INT267144 Positive_regulation of Localization of SELP 2 0.44 3.79 0.38
117 INT323021 Positive_regulation of Regulation of PLEK 1 0.49 0.58 0.37
118 INT44345 Positive_regulation of Negative_regulation of PLEK 1 0.45 0.05 0.35
119 INT118736 Positive_regulation of Transcription of Tlr4 1 0.49 0.42 0.35
120 INT230494 Regulation of Binding of Tlr4 3 0.45 2.97 0.31
121 INT174810 Phosphorylation of SELP 1 0.61 0.74 0.31
122 INT19700 Positive_regulation of Protein_catabolism of PLEK 1 0.49 0.59 0.3
123 INT19699 Protein_catabolism of PLEK 1 0.86 0.58 0.29
124 INT157768 Negative_regulation of Binding of TLR4 1 0.43 0.29 0.27
125 INT101313 Protein_catabolism of Selp 1 0.17 0.94 0.26
126 INT204866 Regulation of Localization of Tlr4 3 0.37 0.66 0.25
127 INT318437 Negative_regulation of Pdpn 1 0.47 0.87 0.25
128 INT216732 Regulation of Localization of SELP 1 0.38 0 0.24
129 INT294737 Transcription of Selp 1 0.11 1.39 0.24
130 INT215080 Positive_regulation of Negative_regulation of Tlr4 1 0.31 0.05 0.23
131 INT301950 Regulation of Regulation of Tlr4 1 0.40 0.32 0.23
132 INT108041 Negative_regulation of Phosphorylation of Selp 1 0.03 0.32 0.22
133 INT108042 Phosphorylation of Selp 1 0.05 0.32 0.22
134 INT42592 Negative_regulation of Transcription of PLEK 1 0.41 0 0.21
135 INT348772 Positive_regulation of Positive_regulation of Tlr4 1 0.61 0.72 0.21
136 INT42593 Transcription of PLEK 1 0.67 0 0.2
137 INT152681 Gene_expression of PDPN 29 0.65 23.06 0.18
138 INT334246 Positive_regulation of Protein_catabolism of Tlr4 1 0.07 0.18 0.18
139 INT349473 Negative_regulation of Positive_regulation of Selp 1 0.17 0.38 0.17
140 INT108192 Regulation of Binding of PLEK 1 0.60 0.17 0.17
141 INT306008 Positive_regulation of Transcription of Tlr4 2 0.50 1.41 0.16
142 INT160121 Localization of PDPN 1 0.73 1.07 0.16
143 INT328709 Negative_regulation of Localization of Selp 1 0.01 0.76 0.16
144 INT285435 Protein_catabolism of TLR4 2 0.62 0.9 0.14
145 INT246424 Negative_regulation of Transcription of TLR4 2 0.41 0.52 0.14
146 INT16719 Positive_regulation of Positive_regulation of PLEK 1 0.45 0.13 0.14
147 INT285265 Regulation of Localization of Selp 1 0.07 0.42 0.13
148 INT285441 Regulation of Localization of TLR4 2 0.38 0.15 0.12
149 INT271406 Positive_regulation of Binding of SELP 1 0.21 0.83 0.12
150 INT170260 Regulation of Gene_expression of SELP 3 0.21 2.67 0.11
151 INT200609 Regulation of Localization of Selp 1 0.20 0.64 0.07
152 INT294739 Negative_regulation of Transcription of Selp 1 0.07 0.18 0.06
153 INT276930 Regulation of Regulation of Tlr4 1 0.17 0.45 0.05
154 INT178482 Regulation of Positive_regulation of Selp 1 0.04 1.38 0.05
155 INT267251 Gene_expression of Ptprj 1 0.12 2.02 0.05
156 INT242899 Negative_regulation of Negative_regulation of TLR4 1 0.20 0.09 0.05
157 INT184726 Negative_regulation of Protein_catabolism of Tlr4 2 0.36 0.21 0.04
158 INT344332 Positive_regulation of Gene_expression of PDPN 1 0.58 0.72 0.04
159 INT344330 Phosphorylation of PDPN 1 0.53 0.15 0.04
160 INT231780 Regulation of Transcription of TLR4 1 0.19 0.62 0.04
161 INT267249 Positive_regulation of Gene_expression of Ptprj 1 0.08 0.39 0.03
162 INT344342 Binding of PDPN 1 0.31 0.74 0
163 INT173624 Negative_regulation of Positive_regulation of SELP 1 0.04 0.38 0
164 INT156580 Negative_regulation of Localization of Selp 1 0.06 0.13 0
165 INT180099 Binding of Plek 1 0.02 0 0
166 INT337311 Negative_regulation of Positive_regulation of TLR4 1 0.35 0 0
167 INT349471 Regulation of Binding of Selp 1 0.18 0 0
168 INT344340 Negative_regulation of Gene_expression of PDPN 1 0.36 1.53 0
169 INT344339 Positive_regulation of PDPN 1 0.39 0.98 0
170 INT267250 Positive_regulation of Ptprj 1 0.08 1.31 0
171 INT344335 Regulation of PDPN 1 0.38 0.41 0
172 INT344343 Transcription of PDPN 1 0.60 0.54 0
173 INT344337 Regulation of Negative_regulation of PDPN 1 0.23 0.05 0
174 INT344334 Negative_regulation of PDPN 1 0.36 2.76 0
175 INT151565 Negative_regulation of Transcription of Tlr4 1 0.41 0.08 0
176 INT344333 Negative_regulation of Binding of PDPN 1 0.36 0.74 0
177 INT184727 Regulation of Protein_catabolism of Tlr4 1 0.38 0.17 0
178 INT202389 Phosphorylation of Pdpn 1 0.61 0 0
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