GO:0010596

From wiki-pain
Jump to: navigation, search
Name negative regulation of endothelial cell migration
Categary Process
Go Slim No
Go Link GO:0010596
Unique Molecular Interactions 80
Total Molecular Interactions 136
Total Single Events 612
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of endothelial cell migration. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of endothelial cell migration. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT125407 Binding of OPRL1 and PTPRM 1 0.03 0.72 4.67
2 INT87267 Binding of BMP8B and KRIT1 1 0.06 0.16 2.69
3 INT87266 Negative_regulation of Binding of BMP8B and KRIT1 1 0.05 0.07 1.37
4 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
5 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
6 INT87275 KRIT1 Regulation of Oprd1 1 0.01 0.08 0.72
7 INT148452 Inhbe Regulation of Acvrl1 1 0.01 0.69 0.69
8 INT150791 THBS1 Negative_regulation of TIMP2 1 0.17 0.5 0.52
9 INT150796 ZNF398 Positive_regulation of THBS1 1 0.06 0.5 0.52
10 INT150785 THBS1 Negative_regulation of MMP2 1 0.10 0.5 0.52
11 INT130930 Egr1 Negative_regulation of Positive_regulation of Thbs1 1 0.58 0.64 0.38
12 INT337890 Per1 Regulation of Nr2f2 1 0.08 0 0.37
13 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
14 INT88252 Binding of RAP1A and Krit1 1 0.36 2.25 0.33
15 INT174311 Binding of Krit1 and Rap1a 1 0.04 1.08 0.28
16 INT96788 Binding of SP3 and NR2F2 1 0.24 0.27 0.27
17 INT96789 Binding of SP1 and NR2F2 1 0.24 0.27 0.27
18 INT337884 Ins1 Negative_regulation of Gene_expression of Nr2f2 1 0.11 0.08 0.27
19 INT337896 Ins1 Negative_regulation of Nr2f2 1 0.15 0.1 0.27
20 INT203733 Thbs1 Positive_regulation of Negative_regulation of Ppara 1 0.36 1.55 0.26
21 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
22 INT311900 Acvrl1 Negative_regulation of Insrr 1 0.00 0.86 0.25
23 INT252356 Binding of THBS1 and Cd47 1 0.00 0.44 0.24
24 INT337892 Positive_regulation of Mc4r Positive_regulation of Gene_expression of Nr2f2 1 0.34 0 0.23
25 INT311908 Acvrl1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
26 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21
27 INT23585 Binding of KRIT1 and CCR1 1 0.40 0.97 0.19
28 INT23586 Binding of CALCR and KRIT1 1 0.40 0.97 0.19
29 INT189563 Binding of SLIT2 and ROBO4 1 0.03 0.71 0.18
30 INT337260 ELL Positive_regulation of Gene_expression of THBS1 1 0.11 0.82 0.18
31 INT337263 ELL Regulation of Gene_expression of THBS1 1 0.10 0.82 0.18
32 INT231677 Binding of CD47 and THBS1 1 0.18 0 0.16
33 INT252352 Binding of THBS1 and Sirpa 1 0.00 0.26 0.15
34 INT337894 Ins1 Regulation of Gene_expression of Nr2f2 1 0.07 0.22 0.15
35 INT96791 NR2F2 Positive_regulation of GDF15 1 0.23 0.14 0.14
36 INT111134 Binding of Krit1 and Rap1a 1 0.07 0.81 0.1
37 INT294439 KLK4 Negative_regulation of THBS1 1 0.01 0 0.1
38 INT322851 Binding of KRIT1 and OSM 1 0.04 1.42 0.09
39 INT348167 Thbs1 Positive_regulation of RAC1 1 0.04 0.71 0.08
40 INT337898 Positive_regulation of MC3R Regulation of Gene_expression of Nr2f2 1 0.30 0 0.08
41 INT348168 Thbs1 Positive_regulation of PIK3CD 1 0.00 0.65 0.07
42 INT311903 Acvrl1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
43 INT311910 Acvrl1 Positive_regulation of Phosphorylation of Smad1 1 0.12 0.24 0.06
44 INT203732 Thbs1 Regulation of Gene_expression of Ppara 1 0.33 0.94 0.05
45 INT341535 F2RL1 Positive_regulation of Gene_expression of THBS1 1 0.28 0.75 0.04
46 INT272528 THBS1 Positive_regulation of TGFB2 1 0.09 0.64 0.03
47 INT337887 Ins1 Regulation of Nr2f2 1 0.07 0 0.03
48 INT275231 Binding of ACVRL1 and AK3 1 0.01 0.72 0
49 INT310186 Binding of Gdf2 and Bmpr2 1 0.02 0 0
50 INT344266 Binding of APOH and CD40LG 1 0.04 0.31 0
51 INT337270 E2F1 Positive_regulation of Transcription of THBS1 1 0.67 0.19 0
52 INT337268 E2F1 Regulation of Transcription of THBS1 1 0.44 0 0
53 INT337274 E2F1 Regulation of THBS1 1 0.44 0 0
54 INT99770 Thbs1 Regulation of PGR 1 0.01 0 0
55 INT337269 Binding of E2F1 and Positive_regulation of Gene_expression of THBS1 1 0.45 0.21 0
56 INT337262 PRB1 Negative_regulation of THBS1 1 0.18 0.61 0
57 INT262750 GLYR1 Positive_regulation of THBS1 1 0.01 0.99 0
58 INT99769 Thbs1 Regulation of THBS1 1 0.00 0 0
59 INT277490 Binding of F2 and Thbs1 1 0.09 0 0
60 INT337264 Binding of E2F1 and THBS1 1 0.47 0.78 0
61 INT268524 MYC Regulation of THBS1 1 0.02 1.85 0
62 INT337273 E2F1 Regulation of Gene_expression of THBS1 1 0.60 0 0
63 INT337266 E2F1 Positive_regulation of Gene_expression of THBS1 1 0.67 0.21 0
64 INT99772 Pgr Regulation of THBS1 1 0.00 0 0
65 INT337885 Ins1 Positive_regulation of Gene_expression of Nr2f2 1 0.18 0.27 0
66 INT253020 Pttg1 Negative_regulation of THBS1 1 0.03 0.16 0
67 INT277489 Binding of Thbs1 and Gopc 1 0.14 0 0
68 INT337891 Per1 Positive_regulation of Nr2f2 1 0.08 0.16 0
69 INT310187 Acvrl1 Regulation of Gene_expression of Bmpr2 1 0.04 0 0
70 INT337265 Negative_regulation of E2F1 Positive_regulation of THBS1 1 0.42 0 0
71 INT337272 E2F1 Positive_regulation of THBS1 1 0.49 1.27 0
72 INT337267 THBS1 Positive_regulation of E2F1 1 0.49 0.05 0
73 INT99771 Oxtr Regulation of THBS1 1 0.01 0 0
74 INT310189 Binding of Acvrl1 and Gdf2 1 0.01 0 0
75 INT310192 Tgfbr1 Positive_regulation of Regulation of Acvrl1 1 0.01 0 0
76 INT337886 Per1 Positive_regulation of Gene_expression of Nr2f2 1 0.09 0.16 0
77 INT337893 Ins1 Positive_regulation of Nr2f2 1 0.12 0.16 0
78 INT268511 MIR19B1 Regulation of THBS1 1 0.20 0.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of endothelial cell migration. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of endothelial cell migration. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT63701 Localization of KRIT1 11 0.78 2.02 9.17
2 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51
3 INT337882 Gene_expression of Nr2f2 1 0.76 3.45 4.6
4 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45
5 INT49433 Binding of PTPRM 2 0.02 0.26 2.15
6 INT337864 Positive_regulation of Gene_expression of Nr2f2 1 0.68 0.48 2.07
7 INT130364 Positive_regulation of Thbs1 7 0.62 7.73 1.97
8 INT49432 Gene_expression of PTPRM 2 0.04 0.27 1.87
9 INT60337 Positive_regulation of THBS1 8 0.46 4.69 1.83
10 INT48218 Gene_expression of KRIT1 16 0.75 7.59 1.8
11 INT87272 Binding of KRIT1 4 0.47 1.2 1.48
12 INT310167 Gene_expression of Acvrl1 2 0.40 5.47 1.4
13 INT288546 Regulation of Positive_regulation of THBS1 1 0.36 2.65 1.27
14 INT118682 Positive_regulation of KRIT1 4 0.67 1.25 1.24
15 INT150805 Localization of THBS1 4 0.46 2.88 1.23
16 INT203729 Binding of Thbs1 1 0.27 3.83 1.1
17 INT130928 Positive_regulation of Gene_expression of Thbs1 7 0.62 5.62 1.08
18 INT99767 Regulation of THBS1 18 0.42 11.51 1.03
19 INT61643 Gene_expression of ACVRL1 9 0.51 9.04 1.03
20 INT87273 Positive_regulation of Localization of KRIT1 1 0.67 0.1 1.02
21 INT337876 Regulation of Nr2f2 1 0.61 0.18 0.96
22 INT337865 Regulation of Gene_expression of Nr2f2 1 0.61 0.31 0.92
23 INT61642 Binding of ACVRL1 5 0.31 7.03 0.87
24 INT337872 Negative_regulation of Gene_expression of Nr2f2 1 0.42 0.55 0.86
25 INT311884 Negative_regulation of Acvrl1 1 0.30 2.16 0.81
26 INT265328 Positive_regulation of Acvrl1 5 0.40 3.18 0.78
27 INT130363 Localization of Thbs1 9 0.75 4.99 0.76
28 INT71599 Phosphorylation of KRIT1 1 0.79 0 0.73
29 INT337873 Positive_regulation of Nr2f2 1 0.68 0.48 0.73
30 INT83194 Binding of APOH 4 0.17 3.92 0.66
31 INT252993 Negative_regulation of THBS1 8 0.55 6.93 0.59
32 INT117145 Negative_regulation of Gene_expression of Thbs1 11 0.43 5.67 0.57
33 INT150808 Negative_regulation of Localization of THBS1 1 0.25 0.5 0.53
34 INT102336 Gene_expression of Krit1 3 0.69 2.54 0.49
35 INT268576 Positive_regulation of Gene_expression of THBS1 2 0.64 2.26 0.47
36 INT203728 Regulation of Binding of Thbs1 1 0.33 2.76 0.42
37 INT133379 Negative_regulation of APOH 1 0.07 0.09 0.42
38 INT203726 Regulation of Thbs1 2 0.33 1.41 0.41
39 INT142598 Negative_regulation of KRIT1 3 0.57 0.57 0.4
40 INT311889 Negative_regulation of Gene_expression of Acvrl1 1 0.22 1.27 0.37
41 INT71598 Positive_regulation of Gene_expression of KRIT1 1 0.49 0 0.37
42 INT130927 Negative_regulation of Thbs1 19 0.59 3.72 0.36
43 INT81221 Positive_regulation of APOH 1 0.02 1.24 0.36
44 INT130344 Gene_expression of APOH 3 0.34 2.87 0.32
45 INT83195 Regulation of Binding of APOH 1 0.13 0.88 0.31
46 INT311895 Regulation of Positive_regulation of Acvrl1 1 0.23 0.97 0.29
47 INT247096 Binding of NR2F2 1 0.01 0.74 0.29
48 INT139741 Positive_regulation of Gene_expression of ACVRL1 2 0.38 1.33 0.28
49 INT130368 Transcription of Thbs1 2 0.69 1.39 0.23
50 INT130360 Positive_regulation of Transcription of Thbs1 1 0.46 1.41 0.23
51 INT222635 Gene_expression of Thbs1 4 0.39 15.2 0.2
52 INT178504 Positive_regulation of Localization of THBS1 2 0.05 1.9 0.19
53 INT309916 Negative_regulation of NR2F2 1 0.02 0.7 0.18
54 INT150084 Binding of Krit1 6 0.23 0.55 0.16
55 INT231474 Binding of THBS1 4 0.34 2.04 0.16
56 INT189590 Positive_regulation of ACVRL1 3 0.08 1.3 0.16
57 INT348150 Binding of Thbs1 1 0.24 2.06 0.15
58 INT297455 Positive_regulation of Gdf2 1 0.01 0.75 0.15
59 INT337879 Negative_regulation of Nr2f2 1 0.42 0 0.13
60 INT189625 Binding of SLIT2 3 0.33 0.49 0.12
61 INT210224 Localization of Acvrl1 1 0.03 0.33 0.12
62 INT348149 Regulation of Gene_expression of Thbs1 1 0.31 1.94 0.1
63 INT348145 Localization of Thbs1 1 0.41 6.72 0.1
64 INT150083 Positive_regulation of Binding of Krit1 1 0.24 0.29 0.1
65 INT119002 Regulation of APOH 1 0.01 0.43 0.09
66 INT222588 Negative_regulation of Gene_expression of Thbs1 2 0.30 7.93 0.07
67 INT158676 Negative_regulation of Gene_expression of KRIT1 1 0.41 0.21 0.07
68 INT160286 Negative_regulation of Krit1 1 0.25 0.19 0.06
69 INT222624 Negative_regulation of Thbs1 2 0.30 8.42 0.04
70 INT99763 Regulation of Thbs1 2 0.23 2.08 0.04
71 INT348152 Positive_regulation of Localization of Thbs1 1 0.24 0.85 0.04
72 INT348157 Regulation of Transcription of Thbs1 1 0.14 0.96 0.04
73 INT348147 Transcription of Thbs1 1 0.27 0.96 0.04
74 INT294469 Transcription of THBS1 2 0.66 0.46 0.03
75 INT337880 Localization of Nr2f2 1 0.69 0.16 0.03
76 INT231690 Negative_regulation of Binding of THBS1 1 0.16 0.37 0.03
77 INT337858 Regulation of Regulation of Nr2f2 1 0.44 0 0.03
78 INT265340 Binding of Acvrl1 3 0.30 0.46 0
79 INT310166 Regulation of Acvrl1 1 0.07 0 0
80 INT337281 Regulation of Gene_expression of THBS1 1 0.57 0.48 0
81 INT277482 Negative_regulation of Transcription of Thbs1 1 0.43 0 0
82 INT252974 Positive_regulation of Negative_regulation of THBS1 1 0.03 0.09 0
83 INT310163 Positive_regulation of Positive_regulation of Acvrl1 1 0.08 0 0
84 INT213595 Localization of SLIT2 1 0.67 0.06 0
85 INT348156 Positive_regulation of Gene_expression of Thbs1 1 0.24 0.9 0
86 INT213593 Gene_expression of SLIT2 1 0.60 0 0
87 INT189611 Negative_regulation of Gene_expression of ACVRL1 1 0.06 0.29 0
88 INT228789 Positive_regulation of Negative_regulation of Thbs1 1 0.26 0.07 0
89 INT337859 Transcription of Nr2f2 1 0.70 0 0
90 INT297259 Regulation of ACVRL1 1 0.18 0.55 0
91 INT348146 Positive_regulation of Thbs1 1 0.25 2.41 0
92 INT277481 Negative_regulation of Negative_regulation of Thbs1 1 0.59 0 0
93 INT252970 Negative_regulation of Positive_regulation of THBS1 1 0.04 0.2 0
94 INT348158 Negative_regulation of Positive_regulation of Thbs1 1 0.22 0.65 0
95 INT337869 Positive_regulation of Positive_regulation of Nr2f2 1 0.46 0.12 0
96 INT310181 Binding of Gdf2 1 0.04 0 0
97 INT207312 Phosphorylation of THBS1 1 0.43 0.28 0
98 INT310182 Gene_expression of Gdf2 1 0.06 0.48 0
99 INT277486 Negative_regulation of Positive_regulation of Thbs1 1 0.43 0 0
100 INT337279 Positive_regulation of Binding of THBS1 1 0.46 0 0
101 INT320827 Negative_regulation of Gene_expression of THBS1 1 0.03 1.52 0
102 INT337868 Binding of Nr2f2 1 0.37 0 0
103 INT337283 Positive_regulation of Regulation of THBS1 1 0.46 0 0
104 INT308503 Regulation of KRIT1 1 0.11 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox