GO:0010614

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Name negative regulation of cardiac muscle hypertrophy
Categary Process
Go Slim No
Go Link GO:0010614
Unique Molecular Interactions 31
Total Molecular Interactions 41
Total Single Events 639
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cardiac muscle hypertrophy. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of cardiac muscle hypertrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73
2 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25
3 INT274899 Positive_regulation of P2rx4 Positive_regulation of Localization of Gtf3a 1 0.02 1.67 0.95
4 INT305406 Binding of CAV3 and ST8SIA2 1 0.16 0 0.86
5 INT126304 Binding of Rgs2 and Pag1 1 0.16 0.41 0.72
6 INT146276 Binding of P2RX4 and P2RX7 1 0.38 0.38 0.43
7 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
8 INT158708 Positive_regulation of P2RX4 Positive_regulation of Localization of Bdnf 1 0.09 0.48 0.3
9 INT158707 P2RX4 Positive_regulation of Localization of Bdnf 1 0.40 0.59 0.29
10 INT165171 Tpsab1 Positive_regulation of Gene_expression of P2RX4 1 0.02 0.47 0.28
11 INT304458 Binding of P2rx4 and P2rx6 1 0.14 0 0.17
12 INT307459 P2rx4 Positive_regulation of Localization of Bdnf 1 0.15 0.1 0.15
13 INT304463 Ass1 Positive_regulation of P2rx4 1 0.01 0 0.14
14 INT304462 Binding of P2rx4 and P2rx5 1 0.17 0 0.08
15 INT304456 Binding of P2rx1 and P2rx4 1 0.14 0 0.07
16 INT304457 Ass1 Positive_regulation of Transcription of P2rx4 1 0.01 0 0.05
17 INT215684 Binding of P2ry2 and P2rx4 1 0.06 0.46 0.03
18 INT280960 Binding of Cav3 and Fig4 1 0.08 0 0
19 INT325599 Pls1 Regulation of Rgs2 1 0.00 0 0
20 INT280969 Binding of Cav3 and Mgst1 1 0.01 0 0
21 INT325603 Pde2a Regulation of Rgs2 1 0.03 0 0
22 INT325612 Rgs2 Regulation of Pde2a 1 0.10 0 0
23 INT325588 Nppa Regulation of Localization of Rgs2 1 0.32 0 0
24 INT325609 Pde2a Positive_regulation of Gene_expression of Rgs2 1 0.12 0 0
25 INT325608 Rgs2 Regulation of Pls1 1 0.00 0 0
26 INT280959 Binding of Cav3 and IgG-2a 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cardiac muscle hypertrophy. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of cardiac muscle hypertrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68
2 INT112427 Positive_regulation of P2rx4 27 0.68 26.29 21.31
3 INT122053 Positive_regulation of P2rx4 16 0.69 13.02 11.98
4 INT98329 Gene_expression of P2RX4 23 0.75 13.13 10.25
5 INT112428 Positive_regulation of Gene_expression of P2rx4 12 0.68 12.67 9.57
6 INT168991 Negative_regulation of P2rx4 9 0.43 12.77 9.39
7 INT168096 Transcription of Cav3 1 0.72 7.23 8.58
8 INT136177 Gene_expression of P2rx4 8 0.75 6.74 8.05
9 INT112430 Negative_regulation of P2rx4 9 0.57 8.4 6.63
10 INT215594 Negative_regulation of Gene_expression of P2rx4 7 0.48 6.46 5.22
11 INT145681 Regulation of P2rx4 4 0.61 3.41 5.09
12 INT158603 Positive_regulation of Gene_expression of P2RX4 7 0.55 5.85 4.56
13 INT136179 Positive_regulation of P2RX4 9 0.67 7.06 4.27
14 INT112429 Negative_regulation of Positive_regulation of P2rx4 4 0.57 4.03 2.94
15 INT93777 Negative_regulation of Rgs2 3 0.43 2.5 2.81
16 INT112431 Positive_regulation of Positive_regulation of P2rx4 2 0.49 3.52 2.81
17 INT122054 Positive_regulation of Positive_regulation of P2rx4 3 0.49 2.85 2.65
18 INT136176 Positive_regulation of Gene_expression of P2rx4 5 0.60 3.18 2.64
19 INT144274 Gene_expression of Cav3 28 0.78 3.21 2.47
20 INT168959 Gene_expression of CAV3 5 0.65 0.7 2.2
21 INT158602 Regulation of P2RX4 3 0.48 2.46 1.7
22 INT168964 Negative_regulation of Gene_expression of CAV3 1 0.47 0 1.68
23 INT146941 Negative_regulation of Positive_regulation of P2rx4 2 0.37 1.36 1.47
24 INT304433 Localization of P2rx4 1 0.69 0 1.44
25 INT304444 Negative_regulation of Gene_expression of P2rx4 1 0.51 0.75 1.43
26 INT168095 Positive_regulation of Transcription of Cav3 1 0.47 0.91 1.2
27 INT168957 Positive_regulation of CAV3 1 0.40 0 1.06
28 INT168960 Binding of CAV3 1 0.30 0 1.05
29 INT146616 Localization of P2RX4 3 0.68 1.65 0.96
30 INT126912 Localization of P2rx4 4 0.70 1.04 0.95
31 INT149903 Localization of Cav3 3 0.80 1.1 0.93
32 INT84571 Gene_expression of Rgs2 6 0.67 3.18 0.89
33 INT168989 Phosphorylation of P2rx4 1 0.13 1.15 0.88
34 INT149905 Negative_regulation of Cav3 2 0.43 0.98 0.82
35 INT304454 Negative_regulation of Localization of P2rx4 1 0.32 0 0.81
36 INT146277 Binding of P2RX4 5 0.45 1.1 0.79
37 INT216509 Negative_regulation of Positive_regulation of P2RX4 1 0.34 1.12 0.73
38 INT271590 Positive_regulation of Transcription of P2rx4 1 0.35 0.4 0.7
39 INT215816 Transcription of P2rx4 1 0.36 0.39 0.7
40 INT136594 Negative_regulation of P2RX4 1 0.57 1.16 0.7
41 INT84570 Positive_regulation of Gene_expression of Rgs2 3 0.50 0.67 0.67
42 INT252418 Binding of P2rx4 2 0.32 0 0.64
43 INT168963 Negative_regulation of Binding of CAV3 1 0.30 0 0.62
44 INT168962 Positive_regulation of Localization of CAV3 1 0.40 0 0.62
45 INT168953 Localization of CAV3 1 0.60 0 0.62
46 INT215722 Regulation of P2rx4 2 0.20 0.89 0.6
47 INT168955 Phosphorylation of CAV3 1 0.56 0 0.58
48 INT304448 Negative_regulation of Regulation of P2rx4 1 0.37 0.09 0.55
49 INT215751 Regulation of Gene_expression of P2rx4 1 0.20 1.33 0.52
50 INT304441 Negative_regulation of Binding of P2rx4 1 0.37 0 0.49
51 INT278118 Positive_regulation of Positive_regulation of P2RX4 1 0.16 0.59 0.49
52 INT230265 Binding of Cav3 2 0.42 0.74 0.44
53 INT168952 Positive_regulation of Gene_expression of CAV3 1 0.49 0 0.4
54 INT149904 Regulation of Gene_expression of Cav3 1 0.27 0.35 0.35
55 INT149906 Regulation of Localization of Cav3 1 0.61 0.41 0.35
56 INT296724 Binding of P2rx4 1 0.29 0 0.35
57 INT146279 Negative_regulation of Gene_expression of P2RX4 2 0.46 0.33 0.28
58 INT215497 Phosphorylation of P2rx4 1 0.11 0 0.28
59 INT158704 Regulation of Localization of P2RX4 1 0.13 0.42 0.25
60 INT325579 Phosphorylation of Rgs2 2 0.55 0.06 0.2
61 INT263243 Regulation of Gene_expression of Rgs2 1 0.27 1.65 0.15
62 INT217015 Transcription of P2RX4 1 0.20 0.05 0.15
63 INT271765 Regulation of Cav3 1 0.05 0 0.14
64 INT304434 Transcription of P2rx4 1 0.60 0 0.11
65 INT325569 Binding of Rgs2 2 0.30 0.19 0.07
66 INT325568 Positive_regulation of Rgs2 1 0.41 0.13 0.05
67 INT304435 Positive_regulation of Negative_regulation of P2rx4 1 0.43 0.05 0.05
68 INT263238 Localization of Rgs2 2 0.75 0.96 0.03
69 INT263239 Negative_regulation of Localization of Rgs2 1 0.43 0.96 0.03
70 INT230264 Positive_regulation of Cav3 4 0.41 0 0
71 INT280966 Negative_regulation of Localization of Cav3 1 0.37 0 0
72 INT263242 Regulation of Rgs2 1 0.27 0.59 0
73 INT325566 Negative_regulation of Gene_expression of Rgs2 1 0.35 0 0
74 INT325567 Positive_regulation of Localization of Rgs2 1 0.41 0 0
75 INT280968 Negative_regulation of Gene_expression of Cav3 1 0.51 0 0
76 INT304449 Regulation of Gene_expression of P2rx4 1 0.39 0 0
77 INT325577 Positive_regulation of Binding of Rgs2 1 0.41 0.05 0
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