GO:0010629

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Name negative regulation of gene expression
Categary Process
Go Slim No
Go Link GO:0010629
Unique Molecular Interactions 2212
Total Molecular Interactions 3233
Total Single Events 27819
Pain Genes Associated 99

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of gene expression. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of gene expression. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
3 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
4 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
5 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
6 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
7 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
8 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
9 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
10 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
11 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
12 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
13 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
14 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
15 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
16 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
17 INT85042 Binding of CCT6A and MAX 1 0.00 0 3.13
18 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
19 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
20 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
21 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
22 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
23 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
24 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
25 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
26 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
27 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
28 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
29 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
30 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
31 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
32 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
33 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
34 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
35 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
36 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
37 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
38 INT85041 Binding of IGHG3 and MAX 1 0.00 0 2.09
39 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
40 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
41 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06
42 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99
43 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
44 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
45 INT165284 Positive_regulation of Nts Positive_regulation of Crh 1 0.40 1.86 1.93
46 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
47 INT165285 Nts Positive_regulation of Crh 1 0.40 1.84 1.91
48 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
49 INT169498 Binding of Oprm1 and Mirlet7a-1 1 0.32 0 1.9
50 INT169570 Binding of ROS1 and TRPV1 3 0.33 3.07 1.89
51 INT349588 Aap Positive_regulation of Gene_expression of Ros1 1 0.06 0.73 1.85
52 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
53 INT169502 Mirlet7a-1 Regulation of Oprm1 1 0.53 0 1.81
54 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
55 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
56 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78
57 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
58 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
59 INT175986 Ros1 Positive_regulation of Gtf3a 2 0.01 4.75 1.71
60 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
61 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
62 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
63 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
64 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
65 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
66 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
67 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
68 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
69 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
70 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
71 INT151020 Binding of Pdyn and Crh 1 0.14 0.42 1.59
72 INT356327 Crh Positive_regulation of Localization of Gabrg1 1 0.17 0 1.58
73 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
74 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
75 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
76 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
77 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
78 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
79 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
80 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
81 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
82 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
83 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
84 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
85 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
86 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4
87 INT222213 TFAM Positive_regulation of Gene_expression of Ccr1 1 0.02 3.96 1.4
88 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
89 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
90 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
91 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
92 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
93 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
94 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
95 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
96 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
97 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
98 INT142431 Cp Positive_regulation of Crh 1 0.31 1.49 1.26
99 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
100 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
101 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
102 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
103 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
104 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
105 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
106 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
107 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
108 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
109 INT29714 Crh Regulation of Localization of LH 2 0.26 0 1.19
110 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
111 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
112 INT349586 Aap Regulation of Gene_expression of Ros1 1 0.03 0.56 1.17
113 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
114 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
115 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
116 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
117 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
118 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
119 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
120 INT29713 Crh Negative_regulation of Localization of Gnrhr 1 0.39 0 1.12
121 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
122 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
123 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
124 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
125 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
126 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
127 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
128 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
129 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
130 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
131 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
132 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
133 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
134 INT85040 Positive_regulation of Binding of CCT6A and MAX 1 0.00 0 1.06
135 INT356316 Crh Positive_regulation of Localization of Cea 1 0.34 0 1.06
136 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
137 INT85039 Binding of GPM6A and MAX 1 0.00 0 1.05
138 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
139 INT38936 Binding of Avp and Crh 7 0.40 0.82 1.04
140 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
141 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
142 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03
143 INT200307 Rest Negative_regulation of Rorb 1 0.00 0.1 1.03
144 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
145 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
146 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
147 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1
148 INT5612 Cck Positive_regulation of Localization of Crh 1 0.65 0.16 1
149 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
150 INT175805 Crh Positive_regulation of Gene_expression of POMC 1 0.12 1.07 0.99
151 INT169500 Negative_regulation of Mirlet7a-1 Regulation of Oprm1 1 0.37 0 0.99
152 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
153 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
154 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
155 INT31494 Pomc Regulation of Crh 2 0.12 0.13 0.97
156 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
157 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
158 INT119276 Negative_regulation of CYBB Negative_regulation of Positive_regulation of ROS1 1 0.09 1.18 0.97
159 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
160 INT119275 Negative_regulation of CYBB Negative_regulation of Gene_expression of ROS1 1 0.09 1.18 0.97
161 INT36002 Negative_regulation of Crh Negative_regulation of LH 2 0.29 0.66 0.96
162 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
163 INT149471 Avp Regulation of Gene_expression of Crh 1 0.45 0.6 0.96
164 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
165 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
166 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
167 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
168 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
169 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
170 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
171 INT265649 TBK1 Negative_regulation of COMT 1 0.01 0.61 0.94
172 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
173 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
174 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
175 INT72917 Binding of Crh and Crhr1 4 0.32 0.73 0.91
176 INT62449 Gnrh1 Regulation of Crh 1 0.40 0.34 0.91
177 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
178 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
179 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
180 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
181 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
182 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
183 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
184 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
185 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
186 INT66371 Pomc Regulation of Gene_expression of Crh 2 0.49 0 0.88
187 INT199189 Binding of Aldh2 and Ros1 1 0.06 0.3 0.88
188 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
189 INT119274 CYBB Positive_regulation of ROS1 1 0.11 1.11 0.88
190 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87
191 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
192 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87
193 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87
194 INT200308 Binding of Rest and Rorb 1 0.00 0 0.87
195 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
196 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
197 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
198 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
199 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
200 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of gene expression. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of gene expression. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT1562 Localization of Crh 499 0.81 126.74 236.68
7 INT6481 Binding of TNF 624 0.48 510.2 214.82
8 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
9 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
10 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
11 INT9660 Regulation of TNF 363 0.62 312.94 139.99
12 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
13 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
14 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83
15 INT1898 Regulation of Crh 220 0.62 61.33 102.64
16 INT10166 Localization of Tnf 237 0.81 153.95 88.64
17 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
18 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5
19 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
20 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
21 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
22 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98
23 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
24 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
25 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
26 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
27 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
28 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
29 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
30 INT13354 Transcription of TNF 108 0.72 85.81 42.32
31 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
32 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56
33 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
34 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08
35 INT77310 Gene_expression of Aif1 89 0.78 50.49 33.68
36 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23
37 INT8691 Localization of Insr 85 0.80 9.27 30.32
38 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
39 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29
40 INT5300 Regulation of Insr 54 0.60 11.33 29.26
41 INT16879 Binding of Crh 72 0.48 21.65 28.43
42 INT116737 Localization of Mif 63 0.81 52.97 28.11
43 INT21379 Transcription of Crh 65 0.72 15.64 27.92
44 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45
45 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21
46 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
47 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2
48 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33
49 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27
50 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14
51 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03
52 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09
53 INT12114 Positive_regulation of Tnfrsf1a 46 0.69 36.26 22.54
54 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
55 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
56 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34
57 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91
58 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73
59 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
60 INT8075 Localization of Crh 64 0.81 25.41 19.45
61 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
62 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
63 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
64 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01
65 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
66 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
67 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
68 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
69 INT21177 Positive_regulation of Crh 39 0.70 17.5 15.28
70 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
71 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
72 INT10173 Binding of Tnf 45 0.48 35.6 14.32
73 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
74 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71
75 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
76 INT142621 Positive_regulation of Gene_expression of CD36 38 0.70 15.18 13.4
77 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
78 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15
79 INT7585 Regulation of Crh 24 0.58 9.88 12.97
80 INT2385 Gene_expression of MIF 57 0.68 40.74 12.78
81 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
82 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5
83 INT55343 Localization of Ros1 39 0.60 34.51 12.5
84 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39
85 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22
86 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
87 INT112003 Localization of ROS1 94 0.73 66.32 12.16
88 INT100821 Localization of Ros1 59 0.60 45.26 11.92
89 INT114674 Gene_expression of Mdm2 15 0.78 3.51 11.85
90 INT72949 Binding of Mif 31 0.46 23.12 11.65
91 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
92 INT128364 Positive_regulation of Ccl3 20 0.70 23.96 10.65
93 INT94784 Binding of ROS1 113 0.40 71.57 10.26
94 INT158863 Negative_regulation of Ros1 84 0.35 40.3 10.14
95 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
96 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
97 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
98 INT56292 Negative_regulation of Gene_expression of Ros1 70 0.38 36.14 9.17
99 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08
100 INT32692 Positive_regulation of Aif1 33 0.35 13.29 9.03
101 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97
102 INT55342 Negative_regulation of Gene_expression of Ros1 49 0.37 31.62 8.93
103 INT141185 Regulation of Ros1 30 0.24 20.73 8.88
104 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
105 INT8903 Gene_expression of IFNA2 58 0.71 38.23 8.68
106 INT117553 Regulation of MIF 10 0.56 12.76 8.67
107 INT77790 Positive_regulation of Gene_expression of Tnfrsf1a 16 0.67 15.88 8.5
108 INT209866 Regulation of Gene_expression of CD36 27 0.60 10.04 8.42
109 INT5498 Positive_regulation of Positive_regulation of Crh 19 0.70 9.82 7.97
110 INT166881 Positive_regulation of Ccr1 31 0.69 18.14 7.9
111 INT114675 Positive_regulation of Gene_expression of Mdm2 1 0.70 1.98 7.9
112 INT75684 Regulation of Aif1 32 0.47 8.03 7.89
113 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
114 INT21179 Negative_regulation of Crh 22 0.58 8.03 7.87
115 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79
116 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
117 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
118 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
119 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
120 INT153271 Localization of Ccl3 7 0.81 11.29 7.14
121 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
122 INT69439 Regulation of ROS1 46 0.45 31.22 6.94
123 INT22336 Positive_regulation of Transcription of Crh 18 0.68 4.61 6.91
124 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
125 INT93144 Gene_expression of CCR1 18 0.75 14.69 6.84
126 INT79770 Regulation of Gene_expression of Aif1 13 0.45 5.28 6.82
127 INT69441 Regulation of Gene_expression of ROS1 38 0.50 26.78 6.78
128 INT87775 Phosphorylation of Gja1 13 0.82 2.75 6.56
129 INT517 Regulation of Mif 16 0.62 5.43 6.55
130 INT5871 Binding of IFNA2 38 0.48 20.35 6.46
131 INT141611 Positive_regulation of Gene_expression of Ccr1 25 0.69 20.32 6.42
132 INT275265 Negative_regulation of Positive_regulation of Tnfrsf1a 1 0.56 4.41 6.35
133 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
134 INT121370 Positive_regulation of MIF 22 0.70 17.79 6.08
135 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
136 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
137 INT143357 Binding of Ros1 48 0.36 27.76 6
138 INT91159 Negative_regulation of Ros1 35 0.44 26.12 5.97
139 INT275272 Positive_regulation of Positive_regulation of Tnfrsf1a 8 0.48 6.44 5.97
140 INT15132 Gene_expression of TNFRSF1A 33 0.75 20.09 5.93
141 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
142 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
143 INT94118 Localization of Tnfrsf1a 9 0.72 7.24 5.81
144 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
145 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69
146 INT105538 Negative_regulation of Tnfrsf1a 16 0.56 12.51 5.61
147 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
148 INT115528 Binding of Ros1 37 0.41 22.96 5.5
149 INT22485 Negative_regulation of Positive_regulation of Crh 13 0.59 4.49 5.46
150 INT97145 Positive_regulation of TBK1 14 0.12 15.32 5.43
151 INT18244 Regulation of Positive_regulation of Crh 11 0.45 3.87 5.41
152 INT111520 Regulation of Tnfrsf1a 10 0.61 7.25 5.41
153 INT183467 Negative_regulation of TBK1 6 0.12 9.89 5.41
154 INT164656 Negative_regulation of Gene_expression of CD36 24 0.57 6.51 5.39
155 INT181022 Binding of Ccr1 15 0.37 10.69 5.37
156 INT97693 Gene_expression of REST 29 0.75 5.51 5.26
157 INT22338 Negative_regulation of Transcription of Crh 11 0.43 2.09 5.24
158 INT5297 Regulation of IFNA2 20 0.56 10.81 5.13
159 INT83442 Negative_regulation of MIF 18 0.57 9.51 5.12
160 INT89959 Positive_regulation of Gene_expression of Aif1 14 0.58 7.44 5.05
161 INT114058 Negative_regulation of Gene_expression of Insr 13 0.31 9.23 4.97
162 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95
163 INT181186 Binding of Rxra 78 0.35 14.93 4.87
164 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
165 INT51392 Negative_regulation of Insr 18 0.27 14.75 4.84
166 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
167 INT97894 Positive_regulation of Gene_expression of Crh 27 0.70 11.82 4.82
168 INT166878 Regulation of Ccl3 9 0.44 8.21 4.81
169 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
170 INT79767 Negative_regulation of Aif1 30 0.42 5.14 4.73
171 INT169492 Gene_expression of Mirlet7a-1 27 0.67 14.85 4.73
172 INT121372 Positive_regulation of Gene_expression of MIF 17 0.60 14.78 4.73
173 INT150237 Localization of Ccr1 10 0.75 9.25 4.72
174 INT153269 Binding of Ccl3 10 0.48 8.87 4.69
175 INT15474 Gene_expression of PLAUR 36 0.75 22.32 4.63
176 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
177 INT79768 Negative_regulation of Gene_expression of Aif1 8 0.58 5.15 4.52
178 INT93739 Positive_regulation of Gene_expression of Tnfrsf1a 11 0.66 11.17 4.44
179 INT118230 Binding of Tnfrsf1a 15 0.42 7.63 4.39
180 INT19777 Binding of Crh 16 0.40 6.65 4.36
181 INT155689 Phosphorylation of Ros1 6 0.32 5.1 4.36
182 INT187836 Binding of Tnfrsf1a 19 0.46 18.08 4.33
183 INT5870 Negative_regulation of IFNA2 20 0.49 12 4.3
184 INT87780 Gene_expression of Gja1 22 0.77 5.84 4.24
185 INT91158 Regulation of Ros1 26 0.25 17 4.23
186 INT51084 Binding of Insr 13 0.30 4.25 4.23
187 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
188 INT103345 Positive_regulation of Gene_expression of BAK1 10 0.57 6.4 4.19
189 INT79234 Positive_regulation of CCL3 15 0.67 11.43 4.15
190 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14
191 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
192 INT83035 Binding of INSR 16 0.47 9.29 4.11
193 INT101301 Gene_expression of Aif1 17 0.42 16.43 4.06
194 INT134008 Transcription of Crh 8 0.59 6.12 3.95
195 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
196 INT65700 Localization of CCR1 7 0.51 4 3.91
197 INT63441 Regulation of Transcription of Crh 9 0.60 4.51 3.9
198 INT176208 Gene_expression of Nr1h2 27 0.59 22.75 3.84
199 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
200 INT144083 Positive_regulation of Gene_expression of Ccl3 10 0.50 8.16 3.81
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