GO:0010641

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Name positive regulation of platelet-derived growth factor receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0010641
Unique Molecular Interactions 70
Total Molecular Interactions 88
Total Single Events 679
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of platelet-derived growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of platelet-derived growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
2 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
3 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
4 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
5 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
6 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
7 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
8 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
9 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
10 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
11 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
12 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55
13 INT160203 Prkcc Positive_regulation of Src 1 0.02 0 0.51
14 INT98737 Src Negative_regulation of Tk1 1 0.22 0.15 0.5
15 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
16 INT84521 Binding of F7 and TF 1 0.06 0.09 0.37
17 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
18 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
19 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
20 INT263382 Src Regulation of Trib3 1 0.00 0.29 0.35
21 INT114809 Selp Positive_regulation of Gene_expression of F3 1 0.00 0.88 0.34
22 INT174266 TNF Regulation of Gene_expression of F3 1 0.00 3.2 0.33
23 INT249490 Phosphorylation of Ephb2 Positive_regulation of Src 1 0.17 0.15 0.33
24 INT174265 IL18 Regulation of Gene_expression of F3 1 0.00 3.21 0.33
25 INT277011 CRP Positive_regulation of Gene_expression of F3 1 0.06 1.03 0.32
26 INT249480 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Src 1 0.22 0.23 0.31
27 INT163903 Binding of EFNB1 and Src 1 0.03 0.56 0.29
28 INT247081 Binding of F5 and F7 1 0.00 0.87 0.28
29 INT191503 CD40LG Regulation of Gene_expression of F3 1 0.01 0.99 0.27
30 INT282647 IL6 Positive_regulation of Gene_expression of F3 1 0.00 1.89 0.27
31 INT282648 IL8 Positive_regulation of Gene_expression of F3 1 0.00 1.89 0.27
32 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
33 INT84522 IRF6 Positive_regulation of Gene_expression of F3 1 0.08 0.1 0.21
34 INT213814 F3 Positive_regulation of Pars2 1 0.01 0.58 0.21
35 INT247084 Binding of F7 and H1F0 1 0.00 0.38 0.17
36 INT281319 Binding of F7 and tf 1 0.24 1 0.16
37 INT220679 Binding of F3 and Gtf3a 1 0.00 0.98 0.15
38 INT191001 F3 Positive_regulation of F2 1 0.00 0.62 0.14
39 INT281301 Stx2 Positive_regulation of Localization of F3 1 0.10 0.19 0.11
40 INT281311 Tlr4 Positive_regulation of Localization of F3 1 0.04 0.19 0.11
41 INT276497 F3 Positive_regulation of F7 1 0.02 1.64 0.1
42 INT276495 TF Positive_regulation of F7 1 0.23 1.63 0.1
43 INT8675 Positive_regulation of Binding of F2 and F3 2 0.17 0.43 0.09
44 INT8671 Binding of F2 and F3 2 0.13 0.42 0.09
45 INT8674 Positive_regulation of Binding of F3 and ANGPTL5 1 0.06 0.48 0.09
46 INT281309 Tlr4 Positive_regulation of Gene_expression of F3 1 0.04 0.15 0.09
47 INT8678 Binding of F3 and ANGPTL5 1 0.04 0.48 0.09
48 INT281312 Stx2 Positive_regulation of Gene_expression of F3 1 0.10 0.15 0.09
49 INT276496 Binding of TF and F7 1 0.18 0.81 0.08
50 INT257221 Negative_regulation of Binding of Src and Pde5a 1 0.03 0 0.08
51 INT257219 Binding of Src and Pde5a 1 0.02 0 0.08
52 INT28705 F7 Negative_regulation of TFPI 1 0.02 0.66 0.06
53 INT269845 Binding of F3 and Hmgn2 1 0.06 1 0.05
54 INT263377 Abl1 Regulation of Src 1 0.15 0 0.04
55 INT263381 Trib3 Regulation of Src 1 0.01 0 0.04
56 INT229006 MIA3 Positive_regulation of Phosphorylation of Src 1 0.02 0.44 0.03
57 INT213024 Cd320 Positive_regulation of Localization of F3 1 0.12 1.16 0
58 INT355636 OLR1 Positive_regulation of Positive_regulation of F3 1 0.01 0.57 0
59 INT213012 Cog1 Positive_regulation of Localization of F3 1 0.02 1.17 0
60 INT269846 Binding of F3 and Ncl 1 0.21 3.19 0
61 INT281296 Binding of Tlr4 and Positive_regulation of Localization of F3 1 0.03 0.32 0
62 INT130413 TNFSF14 Positive_regulation of F3 1 0.11 0 0
63 INT275702 Binding of F3 and DEFB103A 1 0.01 0.16 0
64 INT355640 OLR1 Positive_regulation of Gene_expression of F3 1 0.01 0.57 0
65 INT118344 Binding of Crp and F7 1 0.01 0.19 0
66 INT281316 Binding of St8sia2 and Positive_regulation of Localization of F3 1 0.01 0.32 0
67 INT230416 F3 Regulation of MSLN 1 0.06 0.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of platelet-derived growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of platelet-derived growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT59870 Gene_expression of F3 51 0.65 51.83 14.01
2 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
3 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
4 INT44003 Gene_expression of F3 40 0.75 27.92 8.29
5 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21
6 INT18677 Gene_expression of F3 50 0.65 30.86 5.86
7 INT100222 Binding of Src 9 0.26 5.41 5.37
8 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
9 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
10 INT78493 Negative_regulation of F3 11 0.27 8.35 3.76
11 INT122327 Regulation of Src 6 0.59 0.59 3.6
12 INT84527 Positive_regulation of Gene_expression of F3 16 0.49 15.83 2.85
13 INT28698 Positive_regulation of F7 13 0.64 9.5 2.38
14 INT29402 Gene_expression of Src 16 0.74 4.57 2.29
15 INT46088 Localization of F3 15 0.37 13.7 2.23
16 INT9840 Positive_regulation of F7 17 0.57 17.83 2.08
17 INT92129 Positive_regulation of Gene_expression of F3 13 0.08 12.13 2.02
18 INT249530 Positive_regulation of Positive_regulation of Src 3 0.28 1.32 1.9
19 INT9106 Positive_regulation of F3 8 0.22 4.92 1.85
20 INT81776 Positive_regulation of F3 8 0.07 3.77 1.21
21 INT249522 Positive_regulation of Binding of Src 1 0.22 0.68 1.12
22 INT124167 Regulation of Positive_regulation of Src 2 0.13 0.47 1.1
23 INT88820 Positive_regulation of Gene_expression of F3 8 0.67 5.48 1.08
24 INT44002 Negative_regulation of Gene_expression of F3 5 0.20 1.64 0.98
25 INT100221 Negative_regulation of Phosphorylation of Src 2 0.24 0.74 0.93
26 INT81774 Negative_regulation of F3 5 0.09 3.71 0.79
27 INT249506 Regulation of Phosphorylation of Src 1 0.13 0.48 0.77
28 INT81775 Localization of F3 10 0.61 9.12 0.73
29 INT46087 Regulation of F3 4 0.45 3.49 0.68
30 INT28699 Binding of F7 9 0.35 3.47 0.67
31 INT107779 Negative_regulation of F7 3 0.30 2.99 0.66
32 INT28702 Negative_regulation of F7 6 0.42 3.9 0.63
33 INT92130 Regulation of F3 3 0.44 1.31 0.62
34 INT67346 Regulation of Gene_expression of F3 2 0.13 1.42 0.6
35 INT235996 Negative_regulation of Gene_expression of Src 3 0.09 1.29 0.58
36 INT82930 Localization of F3 3 0.26 2.07 0.54
37 INT174271 Binding of F3 6 0.15 6.85 0.53
38 INT96129 Binding of F3 10 0.36 8.79 0.51
39 INT117998 Positive_regulation of Gene_expression of Src 4 0.36 1.45 0.51
40 INT73485 Binding of F3 3 0.03 1.53 0.51
41 INT249504 Localization of Src 1 0.36 0.32 0.46
42 INT200523 Regulation of F7 2 0.01 1.82 0.38
43 INT247095 Binding of F7 2 0.03 1.91 0.37
44 INT249533 Regulation of Localization of Src 1 0.22 0.22 0.32
45 INT174272 Negative_regulation of Gene_expression of F3 5 0.14 4.06 0.31
46 INT92073 Positive_regulation of Positive_regulation of F7 1 0.47 0.69 0.3
47 INT252656 Positive_regulation of Binding of F3 1 0.07 1.89 0.29
48 INT210686 Regulation of F3 2 0.12 0.91 0.27
49 INT174798 Negative_regulation of Gene_expression of F3 3 0.01 2.09 0.26
50 INT221999 Gene_expression of F7 2 0.65 2.1 0.2
51 INT138506 Negative_regulation of F3 2 0.04 1.23 0.2
52 INT287790 Positive_regulation of Gene_expression of F7 1 0.49 1.55 0.2
53 INT103215 Regulation of F7 1 0.01 1.11 0.17
54 INT35073 Transcription of F3 1 0.03 0.34 0.17
55 INT249526 Positive_regulation of Localization of Src 1 0.24 0.1 0.16
56 INT242196 Positive_regulation of Localization of F3 3 0.09 1.71 0.15
57 INT28701 Gene_expression of F7 1 0.55 1.51 0.12
58 INT212990 Negative_regulation of Localization of F3 1 0.09 0.9 0.12
59 INT129458 Regulation of Localization of F7 1 0.19 0.33 0.08
60 INT129459 Localization of F7 1 0.31 0.33 0.08
61 INT327443 Regulation of Gene_expression of F3 1 0.03 0.67 0.08
62 INT338740 Transcription of Src 1 0.43 1.24 0.07
63 INT9843 Negative_regulation of Positive_regulation of F7 1 0.48 0.83 0.06
64 INT281279 Positive_regulation of Positive_regulation of F3 1 0.07 0 0.06
65 INT338741 Negative_regulation of Binding of Src 1 0.30 0.75 0
66 INT212965 Positive_regulation of Localization of F3 1 0.11 1.16 0
67 INT222000 Regulation of Gene_expression of F7 1 0.08 0.76 0
68 INT222002 Negative_regulation of Gene_expression of F7 1 0.13 0.57 0
69 INT113443 Regulation of Gene_expression of F3 1 0.10 0.06 0
70 INT269842 Negative_regulation of Binding of F3 1 0.33 0.74 0
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