GO:0010669

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Name epithelial structure maintenance
Categary Process
Go Slim No
Go Link GO:0010669
Unique Molecular Interactions 47
Total Molecular Interactions 83
Total Single Events 437
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for epithelial structure maintenance. They are ordered first by their pain relevance and then by number of times they were reported for epithelial structure maintenance. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT332538 Binding of AD5 and Cxadr 1 0.08 0.98 0.76
2 INT177269 Binding of CXADR and NR1H4 1 0.04 0 0.58
3 INT332539 Regulation of Binding of AD5 and Cxadr 1 0.09 0.65 0.44
4 INT93833 Binding of Fos and Srf 1 0.00 0 0.3
5 INT93832 Binding of Elk1 and Srf 1 0.00 0 0.29
6 INT332540 Cxadr Regulation of Gene_expression of AD5 1 0.09 0.25 0.14
7 INT177296 Binding of CXADR and CYP3A4 1 0.30 0 0.09
8 INT216130 SRF Positive_regulation of Gene_expression of EGR1 1 0.49 0.32 0.07
9 INT216129 SRF Positive_regulation of Gene_expression of FOS 1 0.28 0.32 0.07
10 INT178984 Gmeb1 Positive_regulation of CXADR 1 0.00 0 0.05
11 INT177260 CXADR Positive_regulation of SLCO1B1 1 0.34 0 0.05
12 INT177276 Positive_regulation of Binding of CXADR and NR1H4 1 0.04 0 0.05
13 INT178985 Positive_regulation of Gmeb1 Positive_regulation of CXADR 1 0.00 0 0.05
14 INT177282 Regulation of Binding of CXADR and NR1H4 1 0.02 0 0.05
15 INT177291 CXADR Positive_regulation of ABCC2 1 0.22 0 0.05
16 INT177295 Binding of CXADR and ABCB1 1 0.30 0 0.05
17 INT177288 Binding of CXADR and SV2A 1 0.32 0 0.04
18 INT177279 Binding of CXADR and TNFRSF25 1 0.18 0 0.04
19 INT177268 Binding of CXADR and HLA-DRB4 1 0.20 0 0.04
20 INT177281 Binding of CA2 and CXADR 1 0.31 0 0.04
21 INT319558 Positive_regulation of Creb1 Regulation of Srf 1 0.31 0.06 0.04
22 INT319559 Creb1 Regulation of Srf 1 0.28 0.06 0.04
23 INT247819 Cxadr Regulation of Gene_expression of Rasa1 1 0.06 1.04 0.04
24 INT177253 Binding of CXADR and FAUP1 1 0.02 0 0.04
25 INT217858 AD5 Positive_regulation of Gene_expression of CXADR 1 0.17 0.65 0.03
26 INT177258 SV2A Regulation of CXADR 1 0.63 0 0.03
27 INT330484 Binding of Cxadr and Hspg2 1 0.18 0.52 0.03
28 INT132849 Homer1 Regulation of Srf 1 0.01 0.15 0
29 INT177277 CXADR Positive_regulation of CYP2B6 1 0.47 0 0
30 INT177254 Binding of CXADR and NCOA2 1 0.19 0 0
31 INT217857 Binding of CXADR and AD5 1 0.18 3.55 0
32 INT190632 Binding of Srf and Yy1 1 0.20 0.14 0
33 INT177283 Binding of CXADR and GOPC 1 0.16 0 0
34 INT177267 Binding of CXADR and NCOA3 1 0.17 0 0
35 INT177284 FAUP1 Positive_regulation of CXADR 1 0.03 0 0
36 INT247823 Binding of Cxadr and Tjp1 1 0.08 0.4 0
37 INT225590 Ncoa6 Regulation of Srf 1 0.08 0.21 0
38 INT217861 Negative_regulation of Binding of CXADR and AD5 1 0.16 0.45 0
39 INT177289 Binding of CXADR and NCOA1 1 0.17 0 0
40 INT177286 Binding of CXADR and MED1 1 0.27 0 0
41 INT177300 FAUP1 Positive_regulation of Binding of CXADR 1 0.03 0 0
42 INT217859 Binding of CXADR and RPS4X 1 0.03 0.17 0
43 INT177287 CXADR Positive_regulation of ABCB1 1 0.39 0 0
44 INT177266 GSR Positive_regulation of Gene_expression of CXADR 1 0.13 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for epithelial structure maintenance. They are ordered first by their pain relevance and then by number of times they were reported in epithelial structure maintenance. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83952 Gene_expression of Cxadr 24 0.75 22.38 6.77
2 INT119203 Gene_expression of CXADR 64 0.74 11.37 4.41
3 INT169323 Positive_regulation of Gene_expression of Cxadr 4 0.67 4.09 2.77
4 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
5 INT177328 Positive_regulation of CXADR 9 0.48 4.29 2.27
6 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
7 INT247811 Regulation of Gene_expression of Cxadr 2 0.34 2.61 1.77
8 INT120227 Binding of Cxadr 17 0.45 8.02 1.51
9 INT177305 Positive_regulation of Gene_expression of CXADR 7 0.48 1.1 1.51
10 INT161903 Regulation of Cxadr 4 0.43 1.9 1.32
11 INT113865 Binding of CXADR 35 0.46 3.18 1.12
12 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03
13 INT135032 Negative_regulation of SRF 1 0.49 0 1.03
14 INT26531 Regulation of Srf 3 0.18 0.62 0.9
15 INT45293 Transcription of Srf 2 0.47 0.79 0.76
16 INT174158 Negative_regulation of Cxadr 23 0.55 13.74 0.72
17 INT45489 Gene_expression of SRF 5 0.77 3.29 0.71
18 INT113866 Regulation of CXADR 7 0.59 1.67 0.67
19 INT177316 Localization of CXADR 9 0.77 1.05 0.64
20 INT45292 Negative_regulation of Transcription of Srf 1 0.06 0.65 0.59
21 INT120226 Positive_regulation of Cxadr 4 0.44 2.54 0.48
22 INT247794 Localization of Cxadr 4 0.76 3.17 0.45
23 INT18821 Positive_regulation of Gene_expression of Srf 2 0.35 0.63 0.31
24 INT7610 Localization of Srf 3 0.67 0.98 0.27
25 INT332537 Transcription of Cxadr 1 0.46 0.54 0.15
26 INT89766 Binding of SRF 1 0.17 0.89 0.15
27 INT89767 Positive_regulation of Binding of SRF 1 0.23 0.89 0.15
28 INT177302 Transcription of CXADR 20 0.69 0.49 0.12
29 INT177315 Regulation of Gene_expression of CXADR 4 0.26 0.12 0.11
30 INT113863 Regulation of Regulation of CXADR 1 0.06 0 0.1
31 INT177339 Positive_regulation of Localization of CXADR 1 0.45 0 0.1
32 INT22789 Binding of Srf 1 0.37 0.07 0.07
33 INT22790 Positive_regulation of Binding of Srf 1 0.50 0.07 0.07
34 INT190544 Transcription of Srf 1 0.19 0.43 0.06
35 INT190570 Localization of Srf 1 0.20 0.49 0.06
36 INT177313 Phosphorylation of CXADR 1 0.78 0 0.05
37 INT177314 Negative_regulation of Binding of CXADR 4 0.41 0.07 0.04
38 INT247814 Negative_regulation of Localization of Cxadr 1 0.40 0.96 0.04
39 INT225411 Positive_regulation of Srf 1 0.05 0.27 0.03
40 INT268102 Transcription of SRF 1 0.53 0.85 0.03
41 INT225413 Binding of Srf 1 0.10 0.27 0.03
42 INT177308 Negative_regulation of Localization of CXADR 1 0.36 0 0.03
43 INT174192 Negative_regulation of Gene_expression of CXADR 6 0.41 2.79 0
44 INT177332 Negative_regulation of CXADR 5 0.49 0.89 0
45 INT157800 Gene_expression of Srf 2 0.45 0.88 0
46 INT105753 Positive_regulation of Gene_expression of SRF 1 0.01 0.13 0
47 INT177326 Regulation of Localization of CXADR 1 0.43 0 0
48 INT247812 Positive_regulation of Negative_regulation of Cxadr 1 0.41 0.75 0
49 INT247818 Regulation of Negative_regulation of Cxadr 1 0.37 1.31 0
50 INT177331 Positive_regulation of Binding of CXADR 1 0.67 0 0
51 INT105752 Positive_regulation of SRF 1 0.01 0.13 0
52 INT177324 Positive_regulation of Transcription of CXADR 1 0.67 0 0
53 INT177304 Negative_regulation of Transcription of CXADR 1 0.41 0 0
54 INT247805 Negative_regulation of Gene_expression of Cxadr 1 0.41 1.76 0
55 INT268104 Negative_regulation of Gene_expression of SRF 1 0.38 0.16 0
56 INT213446 Regulation of Gene_expression of SRF 1 0.22 0.71 0
57 INT225408 Negative_regulation of Srf 1 0.05 0.39 0
58 INT157799 Negative_regulation of Gene_expression of Srf 1 0.18 0.07 0
59 INT157794 Phosphorylation of Srf 1 0.26 0.07 0
60 INT247809 Negative_regulation of Binding of Cxadr 1 0.41 2.02 0
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