GO:0010700

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Name negative regulation of norepinephrine secretion
Categary Process
Go Slim No
Go Link GO:0010700
Unique Molecular Interactions 389
Total Molecular Interactions 605
Total Single Events 6904
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of norepinephrine secretion. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of norepinephrine secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54
2 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
3 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
4 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
5 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
6 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
7 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
8 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
9 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
10 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
11 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
12 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37
13 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
14 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
15 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
16 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
17 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99
18 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
19 INT165284 Positive_regulation of Nts Positive_regulation of Crh 1 0.40 1.86 1.93
20 INT165285 Nts Positive_regulation of Crh 1 0.40 1.84 1.91
21 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
22 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78
23 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
24 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
25 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
26 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
27 INT151020 Binding of Pdyn and Crh 1 0.14 0.42 1.59
28 INT356327 Crh Positive_regulation of Localization of Gabrg1 1 0.17 0 1.58
29 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
30 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
31 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4
32 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
33 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
34 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 1 0.01 0.81 1.31
35 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
36 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
37 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27
38 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
39 INT142431 Cp Positive_regulation of Crh 1 0.31 1.49 1.26
40 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
41 INT29714 Crh Regulation of Localization of LH 2 0.26 0 1.19
42 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
43 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
44 INT29713 Crh Negative_regulation of Localization of Gnrhr 1 0.39 0 1.12
45 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
46 INT70270 Binding of ADRA2B and Pnoc 2 0.02 0.15 1.08
47 INT329962 Binding of C5 and HEPACAM 1 0.03 2.25 1.06
48 INT356316 Crh Positive_regulation of Localization of Cea 1 0.34 0 1.06
49 INT38936 Binding of Avp and Crh 7 0.40 0.82 1.04
50 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1
51 INT5612 Cck Positive_regulation of Localization of Crh 1 0.65 0.16 1
52 INT175805 Crh Positive_regulation of Gene_expression of POMC 1 0.12 1.07 0.99
53 INT31494 Pomc Regulation of Crh 2 0.12 0.13 0.97
54 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97
55 INT36002 Negative_regulation of Crh Negative_regulation of LH 2 0.29 0.66 0.96
56 INT149471 Avp Regulation of Gene_expression of Crh 1 0.45 0.6 0.96
57 INT61037 Och Positive_regulation of Ptgs1 1 0.00 0 0.95
58 INT72917 Binding of Crh and Crhr1 4 0.32 0.73 0.91
59 INT62449 Gnrh1 Regulation of Crh 1 0.40 0.34 0.91
60 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9
61 INT66371 Pomc Regulation of Gene_expression of Crh 2 0.49 0 0.88
62 INT21006 Oprl1 Regulation of Localization of Crh 1 0.19 0 0.84
63 INT64629 Binding of Gal and Crh 1 0.18 0.1 0.83
64 INT64627 Binding of Oxt and Crh 1 0.07 0.1 0.83
65 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82
66 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79
67 INT36003 Crh Positive_regulation of Localization of LH 2 0.45 0 0.79
68 INT56459 ADRA2C Positive_regulation of Localization of AHSP 1 0.23 0 0.78
69 INT79532 Crh Regulation of Ugt1a10 1 0.00 0 0.76
70 INT28620 Penk Regulation of Crh 2 0.40 0.25 0.75
71 INT252858 C5 Negative_regulation of Positive_regulation of Trpa1 1 0.02 0.78 0.74
72 INT30838 Crh Negative_regulation of D230030E09Rik 1 0.17 0.1 0.73
73 INT290551 Crh Positive_regulation of Etf1 1 0.01 0.38 0.73
74 INT119314 Ptgs1 Regulation of Gene_expression of Ptger2 1 0.01 0.6 0.73
75 INT290544 Negative_regulation of Crh Positive_regulation of Insr 1 0.01 0.3 0.72
76 INT290553 Positive_regulation of Oprk1 Positive_regulation of Crh 1 0.33 0.39 0.72
77 INT5971 Il1a Positive_regulation of Crh 2 0.51 0.57 0.71
78 INT313778 Gene_expression of Crhq1 Negative_regulation of Localization of Crh 1 0.05 0.66 0.71
79 INT12022 Crh Positive_regulation of Localization of Prl 1 0.02 0.14 0.7
80 INT26198 Positive_regulation of Crh Positive_regulation of Localization of POMC 1 0.38 0 0.7
81 INT55205 Prl Positive_regulation of Localization of Crh 1 0.47 0 0.69
82 INT55209 Prl Positive_regulation of Crh 1 0.51 0 0.69
83 INT114735 Mtx1 Regulation of Ptgs1 1 0.01 0.31 0.69
84 INT253825 Cck Positive_regulation of Crh 1 0.74 0 0.69
85 INT253830 Cck Positive_regulation of Crh 1 0.38 0 0.68
86 INT135119 Binding of Pomc and Crh 1 0.35 0 0.67
87 INT103905 Gh Positive_regulation of Positive_regulation of Crh 1 0.08 0.9 0.66
88 INT81832 Binding of ADRA2C and CRYGS 1 0.06 0 0.66
89 INT97508 Negative_regulation of Il1b Positive_regulation of Crh 1 0.31 0.89 0.65
90 INT33561 Crh Positive_regulation of POMC 3 0.45 1.19 0.64
91 INT290545 Crh Positive_regulation of Positive_regulation of Insr 1 0.02 0.06 0.64
92 INT216644 Binding of P2ry1 and P2ry2 1 0.24 0.55 0.64
93 INT290540 Positive_regulation of Crh Positive_regulation of Insr 1 0.02 0.06 0.64
94 INT34212 PSG2 Regulation of Localization of Crh 1 0.02 0.09 0.63
95 INT34211 DNM2 Regulation of Localization of Crh 1 0.01 0.09 0.63
96 INT142432 Regulation of Cp Positive_regulation of Crh 1 0.18 0.75 0.63
97 INT23576 Binding of Penk and Crh 2 0.18 0 0.62
98 INT20162 Crh Regulation of GNRH1 2 0.02 0.07 0.62
99 INT101320 Negative_regulation of Ptgs1 Positive_regulation of Ptgs2 1 0.03 0.2 0.62
100 INT27067 Crh Positive_regulation of Localization of Avp 3 0.18 0.46 0.61
101 INT91391 Crh Regulation of Localization of Gnrh1 2 0.36 1.78 0.61
102 INT55672 Ptgs1 Positive_regulation of Gene_expression of Ik 1 0.03 0.75 0.61
103 INT356328 Crh Positive_regulation of Cea 1 0.26 0.28 0.6
104 INT57246 Crh Positive_regulation of Positive_regulation of Caprin2 1 0.01 0.55 0.6
105 INT104050 Binding of Crh and Nts 1 0.40 0 0.6
106 INT59540 Crh Regulation of Gnrh1 2 0.36 2.61 0.58
107 INT356315 Crh Regulation of Cea 1 0.16 0.08 0.58
108 INT91393 Crh Positive_regulation of SST 1 0.01 0.73 0.58
109 INT54620 IL1B Positive_regulation of Crh 1 0.01 0.39 0.58
110 INT62445 Pomc Negative_regulation of Localization of Crh 1 0.12 0.07 0.58
111 INT30268 Binding of Gnrh1 and Crh 1 0.45 0.65 0.57
112 INT356311 Crh Regulation of Gabrg1 1 0.08 0.08 0.57
113 INT77367 IFNA1 Positive_regulation of Positive_regulation of Crh 1 0.05 0.76 0.57
114 INT30267 Binding of Crh and Gnrhr 1 0.33 0.65 0.57
115 INT98815 Binding of Crhr2 and Ucn 3 0.32 0.5 0.56
116 INT94499 Tnf Positive_regulation of Gene_expression of Crh 1 0.27 0.97 0.56
117 INT141020 Crh Positive_regulation of Gene_expression of Pomc 1 0.05 0.17 0.55
118 INT76200 CASP1 Positive_regulation of Gene_expression of PTGS1 1 0.05 0.16 0.54
119 INT60627 Crh Positive_regulation of Localization of Mc2r 2 0.11 0.44 0.53
120 INT308894 Adp Regulation of P2ry1 1 0.05 0.49 0.53
121 INT87557 Crh Positive_regulation of Prkaca 1 0.27 0 0.52
122 INT205030 Crh Positive_regulation of Crhr1 2 0.54 1.33 0.51
123 INT55208 Prl Negative_regulation of Localization of Crh 1 0.43 0 0.51
124 INT105849 Il1b Positive_regulation of Positive_regulation of Ptgs1 1 0.07 0.38 0.51
125 INT127337 Crh Regulation of LOC308670 1 0.01 0 0.51
126 INT78590 Nos2 Positive_regulation of PTGS1 2 0.00 0.85 0.5
127 INT62446 Il6 Positive_regulation of Crh 1 0.22 0.05 0.5
128 INT330796 P2ry1 Positive_regulation of Ca2 1 0.05 0.06 0.5
129 INT131809 Nfkb1 Positive_regulation of Gene_expression of Ptgs1 1 0.12 0.73 0.48
130 INT27066 Crh Positive_regulation of Localization of Oxt 1 0.40 0 0.48
131 INT129551 Sag Negative_regulation of Gene_expression of Ptgs1 1 0.08 0.88 0.48
132 INT59546 Avp Positive_regulation of Localization of Crh 1 0.05 0.08 0.47
133 INT59548 Negative_regulation of Avp Positive_regulation of Crh 1 0.04 0.08 0.47
134 INT308892 Adp Positive_regulation of P2ry1 1 0.11 0.44 0.47
135 INT28619 Negative_regulation of Penk Regulation of Crh 1 0.41 0 0.46
136 INT103026 Ptgis Positive_regulation of Ptgs1 1 0.02 0.42 0.46
137 INT103029 Calca Positive_regulation of Positive_regulation of Ptgs1 1 0.12 0.41 0.46
138 INT132580 Binding of ADRA2C and Htr1a 1 0.41 0.27 0.45
139 INT62447 Gnrh1 Regulation of Localization of Crh 1 0.40 0.17 0.45
140 INT57983 Il1b Regulation of Crh 1 0.37 0.09 0.44
141 INT57981 Regulation of Il1b Positive_regulation of Crh 1 0.22 0.1 0.44
142 INT30083 Binding of Crh and Lvp1 1 0.00 0.35 0.44
143 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44
144 INT29254 Positive_regulation of ADRA2C Positive_regulation of Localization of GH1 1 0.13 0.06 0.44
145 INT290543 Binding of Crh and Pdyn 1 0.25 1.04 0.43
146 INT273945 Crh Positive_regulation of Gene_expression of Crem 1 0.20 0.52 0.43
147 INT53470 Acsm3 Regulation of Ptgs1 1 0.15 0 0.42
148 INT53469 Negative_regulation of Acsm3 Regulation of Ptgs1 1 0.24 0 0.42
149 INT329960 Binding of C5 and TRAF1 1 0.32 1.04 0.42
150 INT139486 Oprm1 Positive_regulation of Crh 1 0.27 0.1 0.42
151 INT55202 Crh Positive_regulation of Negative_regulation of Prl 1 0.51 0 0.41
152 INT53471 Binding of Ptgs1 and Acsm3 1 0.17 0 0.41
153 INT329958 Binding of C5 and STAT4 1 0.33 0.93 0.41
154 INT91107 Positive_regulation of Ptgs1 Positive_regulation of Localization of Crh 1 0.00 0.56 0.41
155 INT273939 Positive_regulation of Crem Negative_regulation of Transcription of Crh 1 0.18 0.99 0.39
156 INT273956 Binding of Crem and Negative_regulation of Transcription of Crh 1 0.18 0.99 0.39
157 INT134167 Binding of ADRA2A and APLP1 1 0.09 0.64 0.39
158 INT122188 Binding of Crh and Ucn2 2 0.22 0.29 0.38
159 INT203140 Binding of C5ar1 and C5 1 0.39 0.81 0.38
160 INT50553 Negative_regulation of Ptgs1 Negative_regulation of Gene_expression of Tbxa2r 1 0.02 1.37 0.38
161 INT73772 NR3C1 Regulation of Regulation of Crh 1 0.02 0.68 0.38
162 INT356319 ORF61 Regulation of Crh 1 0.00 0.1 0.38
163 INT74244 Ptgs1 Regulation of Positive_regulation of Penk 1 0.09 0.19 0.37
164 INT134168 Binding of ADRA2B and APLP1 1 0.06 0.7 0.37
165 INT25763 Crh Positive_regulation of Prkacb 1 0.56 0.07 0.37
166 INT41460 Crh Regulation of Pomc 1 0.10 0.1 0.36
167 INT93694 Binding of Hspa8 and Ptgs1 1 0.30 0.79 0.36
168 INT26197 Qrfp Regulation of Localization of Crh 1 0.02 0 0.36
169 INT41461 Crh Regulation of Localization of Pomc 1 0.10 0.1 0.36
170 INT66368 Pomc Regulation of Positive_regulation of Crh 1 0.36 0 0.35
171 INT167045 TRPA1 Regulation of PTGS1 1 0.19 0.1 0.35
172 INT25354 Chi3l1 Negative_regulation of Ptgs1 1 0.00 0.39 0.34
173 INT37552 Crh Regulation of Avp 1 0.22 0 0.34
174 INT320694 C5 Regulation of Gene_expression of Il2 1 0.03 2.15 0.34
175 INT320692 C5 Regulation of Gene_expression of Il12a 1 0.03 2.15 0.34
176 INT320693 C5 Regulation of Gene_expression of Il6 1 0.04 2.15 0.34
177 INT5388 PTGS1 Negative_regulation of APRT 1 0.21 0.4 0.34
178 INT37551 Positive_regulation of Crh Regulation of Avp 1 0.38 0 0.34
179 INT320696 C5 Regulation of Gene_expression of TNF 1 0.34 2.15 0.34
180 INT320691 C5 Regulation of Gene_expression of Il1 1 0.06 2.15 0.34
181 INT37553 Crh Regulation of FDX1 1 0.03 0 0.34
182 INT68557 ZNF697 Negative_regulation of PTGS1 1 0.02 0.59 0.33
183 INT280838 Binding of Crh and gr 1 0.06 0 0.33
184 INT30418 Crh Negative_regulation of Localization of Gh1 1 0.41 0.72 0.33
185 INT273955 Creb1 Positive_regulation of Transcription of Crh 1 0.14 0.96 0.33
186 INT30524 Crh Regulation of Oprl1 1 0.15 0.15 0.33
187 INT82904 Crh Negative_regulation of ge 1 0.00 1.3 0.33
188 INT26196 Npy Positive_regulation of Localization of Crh 1 0.40 0 0.33
189 INT60628 Crh Positive_regulation of Pomc 1 0.52 0.17 0.32
190 INT26071 Adarb1 Regulation of Localization of Crh 1 0.01 0.21 0.32
191 INT30420 Crh Positive_regulation of Localization of Gh1 1 0.67 0.47 0.32
192 INT107944 Crh Regulation of Adarb1 1 0.06 0 0.32
193 INT115597 Avp Positive_regulation of Crh 1 0.56 0.79 0.31
194 INT64859 Negative_regulation of PTGS1 Negative_regulation of PTGS2 1 0.07 0.05 0.31
195 INT141019 Crh Positive_regulation of Gene_expression of Pomc 1 0.20 0.1 0.31
196 INT290552 Crh Positive_regulation of Positive_regulation of Pdyn 1 0.38 0.23 0.3
197 INT213062 PTGS1 Regulation of Gene_expression of MMP9 1 0.04 0.25 0.3
198 INT156082 Binding of PTGS1 and AKR1C3 1 0.01 0.31 0.3
199 INT65539 PTGS1 Positive_regulation of Positive_regulation of Nfkb1 1 0.06 0.18 0.3
200 INT62207 Binding of PTGS1 and PTGS2 3 0.06 0.07 0.29

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of norepinephrine secretion. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of norepinephrine secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26
2 INT1562 Localization of Crh 499 0.81 126.74 236.68
3 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6
4 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
5 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
6 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58
7 INT1898 Regulation of Crh 220 0.62 61.33 102.64
8 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97
9 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5
10 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
11 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
12 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04
13 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41
14 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
15 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
16 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29
17 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18
18 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95
19 INT16879 Binding of Crh 72 0.48 21.65 28.43
20 INT21379 Transcription of Crh 65 0.72 15.64 27.92
21 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33
22 INT9886 Gene_expression of Ptgs1 92 0.77 40.66 25.31
23 INT21503 Binding of Ptgs1 45 0.48 15.6 22.29
24 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34
25 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73
26 INT45840 Positive_regulation of Gene_expression of Ptgs1 35 0.50 16.07 20.49
27 INT8075 Localization of Crh 64 0.81 25.41 19.45
28 INT9197 Binding of PTGS1 44 0.48 18.48 16.26
29 INT21177 Positive_regulation of Crh 39 0.70 17.5 15.28
30 INT53080 Positive_regulation of Ptgs1 42 0.42 23.58 14.37
31 INT69166 Positive_regulation of P2ry1 35 0.67 8.41 13.63
32 INT7585 Regulation of Crh 24 0.58 9.88 12.97
33 INT12992 Negative_regulation of Gene_expression of Ptgs1 33 0.42 20.47 11.77
34 INT20457 Regulation of Ptgs1 23 0.48 11.63 11.56
35 INT787 Localization of Ptgs1 31 0.80 12.36 11.55
36 INT93122 Gene_expression of P2ry1 32 0.75 11.82 11.42
37 INT37896 Positive_regulation of Gene_expression of PTGS1 37 0.67 17.28 9.27
38 INT12991 Negative_regulation of Gene_expression of PTGS1 28 0.41 13.39 8.9
39 INT23264 Negative_regulation of Positive_regulation of Ptgs1 16 0.39 8.47 8.9
40 INT52442 Binding of Ptgs1 16 0.35 9.05 8.78
41 INT6573 Regulation of Negative_regulation of Ptgs1 19 0.45 6.16 8.71
42 INT5498 Positive_regulation of Positive_regulation of Crh 19 0.70 9.82 7.97
43 INT21179 Negative_regulation of Crh 22 0.58 8.03 7.87
44 INT20234 Regulation of Gene_expression of Ptgs1 11 0.44 6.55 7.72
45 INT49751 Negative_regulation of Positive_regulation of PTGS1 12 0.45 4.73 7.23
46 INT22336 Positive_regulation of Transcription of Crh 18 0.68 4.61 6.91
47 INT21138 Binding of ADRA2A 16 0.48 5.57 6.8
48 INT25130 Positive_regulation of Negative_regulation of Ptgs1 14 0.50 5.07 6.29
49 INT5678 Gene_expression of ADRA2C 17 0.74 2.62 6.24
50 INT17370 Negative_regulation of Negative_regulation of Ptgs1 16 0.22 6.5 6.12
51 INT48004 Positive_regulation of Negative_regulation of PTGS1 12 0.49 4.07 5.87
52 INT95170 Localization of P2ry1 10 0.78 5.08 5.63
53 INT111683 Gene_expression of P2ry1 22 0.74 7.96 5.59
54 INT18443 Positive_regulation of ADRA2C 12 0.69 2.61 5.48
55 INT22485 Negative_regulation of Positive_regulation of Crh 13 0.59 4.49 5.46
56 INT18244 Regulation of Positive_regulation of Crh 11 0.45 3.87 5.41
57 INT50491 Regulation of Gene_expression of PTGS1 17 0.47 6 5.4
58 INT22338 Negative_regulation of Transcription of Crh 11 0.43 2.09 5.24
59 INT139238 Positive_regulation of P2ry1 19 0.60 9.22 5.15
60 INT39256 Localization of PTGS1 17 0.74 6.62 5.1
61 INT109848 Gene_expression of P2RY1 26 0.62 6.71 4.98
62 INT65509 Regulation of P2ry1 13 0.60 2.38 4.96
63 INT97894 Positive_regulation of Gene_expression of Crh 27 0.70 11.82 4.82
64 INT62500 Transcription of Ptgs1 10 0.56 4.54 4.52
65 INT30160 Positive_regulation of ADRA2B 14 0.29 1.92 4.37
66 INT19777 Binding of Crh 16 0.40 6.65 4.36
67 INT134008 Transcription of Crh 8 0.59 6.12 3.95
68 INT6507 Binding of C5 23 0.48 15.35 3.91
69 INT63441 Regulation of Transcription of Crh 9 0.60 4.51 3.9
70 INT13134 Binding of ADRA2C 11 0.46 0.73 3.86
71 INT69904 Binding of Hc 11 0.35 7.79 3.69
72 INT107074 Gene_expression of C5 14 0.75 9.87 3.64
73 INT135963 Negative_regulation of Hc 19 0.42 12.36 3.63
74 INT103739 Negative_regulation of Gene_expression of Crh 19 0.59 10.19 3.17
75 INT38030 Positive_regulation of P2RY1 15 0.67 5.54 3.17
76 INT77615 Positive_regulation of Negative_regulation of Ptgs1 6 0.50 1.55 3.11
77 INT28715 Negative_regulation of Regulation of Crh 7 0.43 0.97 3.06
78 INT54740 Positive_regulation of Localization of Crh 10 0.47 7.27 3.01
79 INT90402 Positive_regulation of Gene_expression of Ptgs1 13 0.31 4.83 2.88
80 INT145774 Positive_regulation of C5 7 0.67 4.88 2.79
81 INT64147 Gene_expression of C5 15 0.60 16.8 2.78
82 INT215521 Negative_regulation of P2ry1 10 0.56 2.68 2.72
83 INT121683 Gene_expression of Hc 23 0.75 7.15 2.7
84 INT235853 Regulation of Gene_expression of Crh 7 0.51 1.98 2.66
85 INT5510 Negative_regulation of Negative_regulation of Crh 8 0.43 1.05 2.61
86 INT27607 Localization of Ptgs1 7 0.59 3.22 2.6
87 INT22339 Positive_regulation of Negative_regulation of Crh 5 0.67 1.36 2.59
88 INT122187 Positive_regulation of Crhr2 3 0.58 2.46 2.56
89 INT34969 Negative_regulation of Binding of Ptgs1 4 0.37 1.55 2.55
90 INT70197 Negative_regulation of Positive_regulation of Ptgs1 6 0.24 2.61 2.44
91 INT53476 Positive_regulation of Localization of Ptgs1 6 0.49 2.88 2.35
92 INT53540 Gene_expression of ADRA2B 10 0.46 1.78 2.33
93 INT101955 Gene_expression of Crhr2 6 0.64 3.62 2.31
94 INT9887 Negative_regulation of Gene_expression of Ptgs1 7 0.42 2.94 2.3
95 INT115401 Negative_regulation of P2ry1 6 0.42 1.27 2.25
96 INT88241 Positive_regulation of Positive_regulation of Ptgs1 3 0.45 1.71 2.25
97 INT99844 Localization of P2ry1 7 0.74 4.05 2.19
98 INT54823 Phosphorylation of PTGS1 4 0.51 1.61 2.14
99 INT32557 Negative_regulation of Negative_regulation of PTGS1 8 0.43 3.44 2.1
100 INT101985 Positive_regulation of Positive_regulation of Ptgs1 4 0.15 4.13 1.98
101 INT103236 Positive_regulation of Positive_regulation of P2ry1 5 0.54 2.39 1.92
102 INT23426 Regulation of ADRA2A 8 0.48 1.81 1.88
103 INT135961 Positive_regulation of Hc 8 0.67 3.67 1.87
104 INT30834 Regulation of Negative_regulation of Crh 3 0.45 0.62 1.81
105 INT53812 Regulation of Gene_expression of Ptgs1 5 0.38 0.89 1.78
106 INT64915 Regulation of Negative_regulation of PTGS1 4 0.20 1.81 1.76
107 INT142929 Regulation of Crhr2 1 0.44 1.28 1.73
108 INT29084 Regulation of Localization of Crh 4 0.29 1.24 1.72
109 INT111682 Transcription of P2ry1 4 0.52 1.26 1.71
110 INT78956 Regulation of Transcription of Ptgs1 3 0.35 1.42 1.7
111 INT59077 Transcription of PTGS1 11 0.43 2.37 1.65
112 INT26426 Localization of C5 5 0.78 3.87 1.61
113 INT60857 Negative_regulation of Regulation of Ptgs1 1 0.07 2.22 1.61
114 INT18710 Regulation of Regulation of Crh 6 0.60 0.79 1.6
115 INT212790 Regulation of C5 6 0.24 6.04 1.59
116 INT43327 Positive_regulation of ADRA2A 3 0.46 1.54 1.53
117 INT89209 Negative_regulation of Binding of Ptgs1 6 0.06 2.7 1.39
118 INT73260 Regulation of Positive_regulation of PTGS1 3 0.26 2.65 1.37
119 INT101954 Binding of Crhr2 4 0.31 1.23 1.34
120 INT55318 Localization of ADRA2C 3 0.73 1.39 1.3
121 INT21178 Positive_regulation of Negative_regulation of Crh 1 0.37 0.13 1.28
122 INT30161 Negative_regulation of Positive_regulation of ADRA2B 2 0.05 0.25 1.24
123 INT28888 Positive_regulation of Crhr2 6 0.68 3.8 1.23
124 INT231592 Binding of ADRA2B 5 0.18 0.13 1.23
125 INT107942 Positive_regulation of C5 9 0.50 6.86 1.19
126 INT130198 Negative_regulation of Binding of PTGS1 3 0.34 2.6 1.16
127 INT111681 Regulation of P2ry1 8 0.45 2.64 1.11
128 INT6519 Positive_regulation of Gene_expression of ADRA2C 3 0.44 0.71 1.1
129 INT25043 Positive_regulation of Regulation of Crh 5 0.50 1 1.06
130 INT78353 Positive_regulation of Positive_regulation of PTGS1 4 0.27 0.95 1.06
131 INT145773 Positive_regulation of Localization of C5 1 0.49 1.15 1.06
132 INT12976 Negative_regulation of ADRA2A 4 0.50 0.16 1.01
133 INT63284 Transcription of Ptgs1 5 0.66 1.34 0.97
134 INT62980 Protein_catabolism of Ptgs1 3 0.59 0.93 0.97
135 INT103235 Regulation of Localization of P2ry1 2 0.44 0.09 0.97
136 INT100142 Negative_regulation of Localization of PTGS1 2 0.35 1.71 0.91
137 INT69553 Negative_regulation of Regulation of PTGS1 1 0.16 0.78 0.91
138 INT93406 Positive_regulation of Regulation of Ptgs1 2 0.14 0 0.9
139 INT80142 Positive_regulation of Localization of PTGS1 4 0.21 1.52 0.87
140 INT35292 Negative_regulation of C5 7 0.43 5.3 0.86
141 INT95468 Transcription of P2ry1 4 0.60 0 0.86
142 INT58050 Regulation of Binding of Crh 2 0.42 0.84 0.86
143 INT167317 Negative_regulation of P2RY1 5 0.34 1.35 0.83
144 INT184351 Localization of Hc 2 0.20 2.33 0.83
145 INT269693 Regulation of Negative_regulation of Hc 1 0.00 0.09 0.83
146 INT40928 Regulation of Binding of ADRA2C 1 0.43 0 0.82
147 INT104040 Regulation of Crhr2 2 0.36 1.29 0.81
148 INT329967 Positive_regulation of Gene_expression of C5 1 0.42 1.63 0.81
149 INT14130 Regulation of ADRA2C 4 0.45 1.57 0.79
150 INT101952 Negative_regulation of Crhr2 1 0.17 0.97 0.77
151 INT18836 Localization of ADRA2A 2 0.38 0.33 0.76
152 INT280771 Positive_regulation of Positive_regulation of Crh 2 0.41 0.21 0.76
153 INT55317 Transcription of ADRA2C 6 0.63 0.36 0.74
154 INT148302 Regulation of Regulation of P2ry1 1 0.44 0.09 0.74
155 INT140282 Negative_regulation of Positive_regulation of Crh 3 0.39 1.09 0.71
156 INT111406 Binding of P2ry1 2 0.36 0.31 0.7
157 INT121684 Positive_regulation of Gene_expression of Hc 3 0.67 1.56 0.69
158 INT161201 Localization of C5 2 0.75 0.93 0.69
159 INT252856 Positive_regulation of Positive_regulation of C5 1 0.02 0.95 0.67
160 INT142429 Positive_regulation of Transcription of Crh 1 0.47 0.73 0.67
161 INT93854 Positive_regulation of Transcription of Ptgs1 3 0.19 0.54 0.66
162 INT134009 Regulation of Transcription of Crh 2 0.37 1.1 0.66
163 INT157225 Negative_regulation of Gene_expression of Hc 2 0.12 1.12 0.66
164 INT28889 Transcription of Crhr2 2 0.64 1.13 0.66
165 INT25761 Regulation of Positive_regulation of Crh 1 0.45 0.15 0.65
166 INT23612 Regulation of Negative_regulation of Ptgs1 3 0.19 0.69 0.64
167 INT203146 Protein_catabolism of C5 1 0.64 1.62 0.64
168 INT166437 Binding of C5 4 0.36 3.28 0.63
169 INT216662 Regulation of Gene_expression of P2ry1 1 0.24 0.2 0.63
170 INT184367 Protein_catabolism of Hc 4 0.26 2.66 0.6
171 INT29256 Positive_regulation of Positive_regulation of ADRA2C 2 0.46 0.06 0.59
172 INT108319 Regulation of Positive_regulation of Ptgs1 1 0.16 0.08 0.57
173 INT93647 Regulation of P2RY1 7 0.36 2.13 0.55
174 INT215572 Negative_regulation of Localization of P2ry1 1 0.15 0.08 0.55
175 INT101949 Negative_regulation of Binding of Crhr2 1 0.24 0.6 0.55
176 INT124836 Positive_regulation of Binding of Ptgs1 1 0.10 0.25 0.55
177 INT259774 Negative_regulation of Positive_regulation of P2ry1 1 0.33 1.11 0.54
178 INT30428 Positive_regulation of Binding of ADRA2A 1 0.34 0.59 0.53
179 INT87959 Phosphorylation of Ptgs1 3 0.63 0.37 0.51
180 INT18442 Negative_regulation of ADRA2C 2 0.49 0.61 0.51
181 INT85081 Protein_catabolism of C5 5 0.19 1.34 0.5
182 INT233484 Positive_regulation of Gene_expression of P2ry1 4 0.43 0.95 0.5
183 INT308880 Positive_regulation of Negative_regulation of P2ry1 1 0.48 0.13 0.49
184 INT68529 Negative_regulation of ADRA2B 3 0.14 0.79 0.47
185 INT91220 Positive_regulation of Binding of Ptgs1 1 0.02 0.76 0.47
186 INT29102 Transcription of ADRA2A 2 0.27 0.83 0.46
187 INT39228 Regulation of Regulation of Ptgs1 2 0.39 0.38 0.45
188 INT61414 Positive_regulation of Gene_expression of ADRA2B 2 0.18 0.13 0.44
189 INT19776 Positive_regulation of Binding of Crh 1 0.43 0 0.44
190 INT148784 Negative_regulation of Crhr2 2 0.40 0.76 0.42
191 INT191930 Negative_regulation of Negative_regulation of Ptgs1 1 0.07 0.94 0.42
192 INT83897 Protein_catabolism of Crh 2 0.86 1.75 0.39
193 INT6492 Regulation of ADRA2B 2 0.06 0.31 0.38
194 INT29100 Negative_regulation of Binding of ADRA2A 1 0.19 0.84 0.37
195 INT144599 Gene_expression of Crhr2 3 0.49 2.16 0.36
196 INT185697 Positive_regulation of Positive_regulation of P2RY1 1 0.40 0.36 0.36
197 INT231345 Positive_regulation of Localization of Ptgs1 1 0.16 0.82 0.36
198 INT27059 Negative_regulation of C5 2 0.42 1.87 0.35
199 INT217014 Transcription of P2RY1 1 0.23 0.26 0.35
200 INT207775 Negative_regulation of Gene_expression of C5 4 0.42 2.08 0.33
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