GO:0010718

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Name positive regulation of epithelial to mesenchymal transition
Categary Process
Go Slim No
Go Link GO:0010718
Unique Molecular Interactions 695
Total Molecular Interactions 863
Total Single Events 5837
Pain Genes Associated 36

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of epithelial to mesenchymal transition. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of epithelial to mesenchymal transition. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
2 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
3 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
4 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
5 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
6 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
7 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
8 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
9 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
10 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
11 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
12 INT275097 Twist1 Regulation of Ltp 1 0.01 0.37 0.96
13 INT142709 Binding of TWIST1 and CEBPZ 2 0.17 1.16 0.95
14 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
15 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
16 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
17 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
18 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
19 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
20 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
21 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
22 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
23 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
24 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
25 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
26 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
27 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
28 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
29 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
30 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
31 INT63594 Snai1 Negative_regulation of Binding of Ugt1a2 1 0.05 0.32 0.82
32 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
33 INT63596 Snai1 Negative_regulation of ITS 1 0.00 0.31 0.81
34 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8
35 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
36 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
37 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
38 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
39 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
40 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
41 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
42 INT243626 Twist1 Regulation of Hand1 1 0.15 1.55 0.72
43 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
44 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
45 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65
46 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
47 INT102864 Prkaca Regulation of Twist1 1 0.48 0.05 0.58
48 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
49 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
50 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
51 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
52 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
53 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
54 INT192159 Mmp14 Regulation of Protein_catabolism of Col1a1 1 0.02 1.01 0.52
55 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
56 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
57 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
58 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
59 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
60 INT102364 BRD1 Positive_regulation of Twist1 1 0.00 0 0.47
61 INT117531 Twist1 Regulation of CSAD 1 0.00 0.85 0.47
62 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
63 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
64 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
65 INT72089 TGFB2 Positive_regulation of POMC 1 0.11 0 0.46
66 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
67 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
68 INT169478 TGFB3 Positive_regulation of Tgfa 1 0.01 0.9 0.44
69 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
70 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43
71 INT169465 TGFB3 Positive_regulation of MTG1 1 0.03 0.89 0.43
72 INT102862 Prkaca Regulation of Phosphorylation of Twist1 1 0.19 0.1 0.42
73 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
74 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
75 INT152158 NENF Regulation of TWIST1 1 0.01 0.33 0.4
76 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
77 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
78 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
79 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
80 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
81 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
82 INT243627 Twist1 Regulation of Gene_expression of Ik 1 0.01 0.13 0.34
83 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
84 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
85 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
86 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
87 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
88 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
89 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
90 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
91 INT243641 Twist1 Positive_regulation of Socs1 1 0.14 0.13 0.31
92 INT243634 Twist1 Regulation of Socs1 1 0.14 0.13 0.31
93 INT243625 Stat4 Positive_regulation of Gene_expression of Twist1 1 0.39 0.75 0.3
94 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
95 INT243630 Il12a Positive_regulation of Gene_expression of Twist1 1 0.18 0.69 0.3
96 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
97 INT200640 Agtr2 Positive_regulation of Gene_expression of TGFB1 1 0.03 1.35 0.29
98 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
99 INT137023 Gene_expression of SMAD2 Negative_regulation of Gene_expression of Acta2 1 0.00 0.43 0.29
100 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
101 INT300552 Napa Positive_regulation of Gene_expression of TGFB1 1 0.01 0.88 0.29
102 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
103 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
104 INT137014 Positive_regulation of Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
105 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
106 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
107 INT137012 Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
108 INT137032 Il6 Positive_regulation of Localization of Tgfb1 1 0.04 0.51 0.27
109 INT83395 Binding of IL1RN and Tgfb1 1 0.01 0.17 0.26
110 INT139094 Csf2 Regulation of Tgfb1 1 0.42 0.58 0.26
111 INT271450 Thy1 Regulation of TGFB1 1 0.00 0.62 0.25
112 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25
113 INT271446 Thy1 Regulation of Col1a1 1 0.05 0.61 0.25
114 INT275092 Twist1 Regulation of stm 1 0.00 0 0.25
115 INT243640 Binding of Twist1 and Stub1 1 0.08 0.34 0.24
116 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24
117 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24
118 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24
119 INT235125 PDE2A Negative_regulation of Twist1 1 0.00 0.99 0.24
120 INT9720 Binding of TGFB1 and Egf 1 0.01 0 0.23
121 INT168710 Ifng Regulation of TGFB1 1 0.00 0.3 0.23
122 INT112596 Tgfb1 Negative_regulation of Negative_regulation of Mptp1 1 0.26 0.72 0.22
123 INT112595 Tgfb1 Negative_regulation of Gene_expression of Mptp1 1 0.27 0.72 0.22
124 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21
125 INT316810 Sparc Regulation of Col1a1 1 0.13 0.48 0.21
126 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21
127 INT114905 TGFB1 Positive_regulation of Transcription of COL7A1 1 0.02 0.08 0.21
128 INT209851 TGFB2 Negative_regulation of Gene_expression of CD36 1 0.16 0.16 0.21
129 INT225099 ZNF630 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.2
130 INT297544 Pou3f3 Regulation of Notch1 1 0.06 0.41 0.2
131 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2
132 INT92692 Tgfb1 Positive_regulation of Gene_expression of Fn1 1 0.27 0.91 0.2
133 INT92693 Tgfb1 Positive_regulation of Fgf2 1 0.32 0.9 0.2
134 INT280260 Tgfb1 Positive_regulation of Cxcr1 1 0.07 1.78 0.19
135 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19
136 INT14869 Binding of EGF and TGFB3 1 0.14 0.69 0.19
137 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19
138 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19
139 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
140 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
141 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
142 INT280261 Tgfb1 Positive_regulation of Gene_expression of Cxcr1 1 0.05 1.81 0.19
143 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19
144 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19
145 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18
146 INT350603 MIR25 Regulation of TGFB1 1 0.01 0.42 0.18
147 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18
148 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
149 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
150 INT85334 Agtr2 Regulation of Regulation of Tgfb1 1 0.23 0.68 0.17
151 INT296037 TGFB1 Positive_regulation of IL17A 1 0.02 0 0.17
152 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16
153 INT219601 Pde4a Negative_regulation of Twist1 1 0.10 0 0.16
154 INT333447 Binding of SMAD2 and RXRA 1 0.04 0 0.16
155 INT160083 TGFB1 Positive_regulation of Gene_expression of L1CAM 1 0.16 1.53 0.16
156 INT219598 Pde4a Negative_regulation of Gene_expression of Twist1 1 0.10 0 0.16
157 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
158 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
159 INT208458 TWIST1 Positive_regulation of Localization of Bdnf 1 0.01 0.19 0.15
160 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
161 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
162 INT316479 Il6 Positive_regulation of Snai1 1 0.24 0.33 0.15
163 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
164 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14
165 INT299550 TGFB1 Negative_regulation of Glul 1 0.01 0.34 0.14
166 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13
167 INT296031 Negative_regulation of TGFB1 Regulation of IL10 1 0.01 1.01 0.13
168 INT296027 TGFB1 Regulation of TH1L 1 0.02 1 0.13
169 INT301414 Binding of Enpp2 and Twist1 1 0.08 1.26 0.13
170 INT157602 Binding of COL1A1 and COL3A1 1 0.04 0 0.13
171 INT299547 Negative_regulation of Binding of TGFB1 and Egf 1 0.02 0.1 0.13
172 INT69687 Tgfb1 Positive_regulation of Gene_expression of Il4 1 0.23 0 0.12
173 INT296080 TGFB1 Regulation of Hand2 1 0.01 1 0.12
174 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12
175 INT243642 Binding of Nfatc1 and Twist1 1 0.08 0.23 0.12
176 INT172976 Mras Regulation of Gene_expression of Smad4 1 0.00 0.83 0.12
177 INT296028 TGFB1 Regulation of IL10 1 0.01 1 0.12
178 INT69688 Tgfb1 Positive_regulation of Rel 1 0.50 0 0.12
179 INT316813 Sparc Negative_regulation of Gene_expression of Col1a1 1 0.13 0.67 0.12
180 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
181 INT296038 TGFB1 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11
182 INT299551 Regulation of Binding of TGFB1 and Egf 1 0.03 0.21 0.11
183 INT300313 TGFB1 Positive_regulation of Mapk14 1 0.01 1.5 0.11
184 INT294445 KLK4 Negative_regulation of COL1A1 1 0.01 0 0.1
185 INT297546 Neurod1 Regulation of Notch1 1 0.05 0.2 0.1
186 INT316823 Sparc Positive_regulation of Phosphorylation of Smad2 1 0.44 0.49 0.1
187 INT302287 Twist1 Positive_regulation of Positive_regulation of PTGER2 1 0.03 1.16 0.1
188 INT149178 IL4 Negative_regulation of Positive_regulation of TGFB2 1 0.15 0.29 0.1
189 INT302288 Twist1 Positive_regulation of PTGER2 1 0.03 1.16 0.1
190 INT179869 COL1A1 Positive_regulation of SOCS3 1 0.04 0.99 0.1
191 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1
192 INT238038 Binding of BMP2 and OPLL 1 0.20 2.45 0.09
193 INT299555 Lifr Positive_regulation of Gene_expression of TGFB1 1 0.03 0.23 0.09
194 INT278217 Binding of Ciita and Notch1 1 0.41 0.22 0.09
195 INT116789 Bsg Positive_regulation of Gene_expression of Tgfb1 1 0.00 0.18 0.09
196 INT127143 Binding of IL6 and TGFB1 2 0.01 0.16 0.08
197 INT340505 Binding of Twist1 and Mgat4b 1 0.01 0.45 0.08
198 INT58630 Calca Negative_regulation of Positive_regulation of COL1A1 1 0.02 0.23 0.08
199 INT296041 Binding of TGFB1 and IL21 1 0.01 0.05 0.08
200 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of epithelial to mesenchymal transition. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of epithelial to mesenchymal transition. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
2 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
3 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
4 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
5 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
6 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
7 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15
8 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
9 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32
10 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
11 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47
12 INT1223 Negative_regulation of Snai1 15 0.38 2.05 8.46
13 INT20914 Positive_regulation of Snai1 13 0.41 3.41 7.69
14 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
15 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98
16 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
17 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
18 INT136664 Positive_regulation of Gene_expression of Twist1 49 0.69 25.91 5.41
19 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36
20 INT94028 Regulation of Twist1 37 0.44 22.41 5.33
21 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
22 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
23 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
24 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77
25 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
26 INT19965 Positive_regulation of COL1A1 23 0.45 14.49 4.38
27 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
28 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
29 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
30 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
31 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
32 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
33 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
34 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
35 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4
36 INT81229 Binding of COL1A1 24 0.35 12.07 3.3
37 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
38 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
39 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
40 INT67719 Positive_regulation of Col1a1 21 0.44 8.87 3.12
41 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
42 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
43 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
44 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96
45 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
46 INT116540 Binding of Twist1 35 0.48 16.32 2.85
47 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
48 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
49 INT1225 Regulation of Snai1 10 0.30 1.05 2.72
50 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
51 INT68091 Localization of COL1A1 19 0.66 9.13 2.56
52 INT127113 Positive_regulation of Phosphorylation of Smad2 1 0.68 2.38 2.51
53 INT8890 Transcription of Col1a1 10 0.63 4.02 2.48
54 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
55 INT79261 Positive_regulation of Gene_expression of COL1A1 24 0.36 7.49 2.45
56 INT97152 Protein_catabolism of COL1A1 11 0.74 8.03 2.3
57 INT269217 Gene_expression of SNAI1 81 0.76 80.49 2.26
58 INT194504 Gene_expression of Smad2 27 0.65 7.45 2.25
59 INT126513 Gene_expression of Col1a1 23 0.75 10.92 2.18
60 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
61 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
62 INT113717 Negative_regulation of Gene_expression of COL1A1 21 0.41 6.14 2.01
63 INT48880 Positive_regulation of TWIST1 15 0.59 8.6 1.98
64 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
65 INT120857 Localization of Col1a1 10 0.71 2.33 1.93
66 INT107178 Gene_expression of Smad4 12 0.65 9.85 1.92
67 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
68 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
69 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
70 INT96116 Transcription of COL1A1 10 0.44 4.57 1.81
71 INT102861 Phosphorylation of Twist1 6 0.70 0.86 1.81
72 INT32024 Positive_regulation of Positive_regulation of Snai1 2 0.25 0.32 1.7
73 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
74 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
75 INT55302 Binding of Snai1 2 0.31 1.94 1.63
76 INT180238 Regulation of Gene_expression of Twist1 13 0.61 4.87 1.59
77 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57
78 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
79 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
80 INT127115 Regulation of Phosphorylation of Smad2 1 0.60 1.74 1.53
81 INT153201 Negative_regulation of Gene_expression of Col1a1 7 0.38 6.37 1.52
82 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
83 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
84 INT142719 Binding of Col1a1 7 0.34 5.83 1.47
85 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
86 INT255251 Negative_regulation of Smad2 12 0.32 5.69 1.44
87 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
88 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
89 INT102860 Positive_regulation of Phosphorylation of Twist1 1 0.35 0.15 1.42
90 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
91 INT10873 Localization of Twist1 21 0.74 10.43 1.37
92 INT219579 Negative_regulation of Gene_expression of Twist1 12 0.43 9.07 1.36
93 INT129619 Phosphorylation of Smad2 34 0.61 11.6 1.34
94 INT120860 Positive_regulation of Gene_expression of Col1a1 12 0.44 4.84 1.34
95 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
96 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
97 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
98 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
99 INT112650 Positive_regulation of Col1a1 3 0.30 5.96 1.3
100 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
101 INT59473 Negative_regulation of Col1a1 4 0.25 1.33 1.24
102 INT243621 Transcription of Twist1 13 0.71 4.08 1.23
103 INT71845 Positive_regulation of Positive_regulation of Col1a1 1 0.34 0.15 1.23
104 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
105 INT140033 Positive_regulation of Gene_expression of Col1a1 6 0.14 3.68 1.2
106 INT110780 Localization of Notch1 2 0.06 0.47 1.19
107 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
108 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
109 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
110 INT184720 Negative_regulation of Smad3 8 0.55 5.23 1.1
111 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
112 INT97032 Gene_expression of Snai1 3 0.52 0.58 1.04
113 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
114 INT156614 Regulation of Gene_expression of COL1A1 6 0.33 2.51 0.99
115 INT141475 Negative_regulation of Gene_expression of TWIST1 5 0.41 3.94 0.97
116 INT81878 Gene_expression of TGFB2 3 0.42 2.02 0.97
117 INT129997 Protein_catabolism of Col1a1 5 0.96 3.43 0.96
118 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
119 INT6833 Binding of Notch1 4 0.36 0.05 0.94
120 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
121 INT218696 Negative_regulation of Phosphorylation of Smad2 3 0.42 4.36 0.92
122 INT114664 Binding of BMP2 12 0.37 6.54 0.91
123 INT8888 Regulation of Col1a1 4 0.13 1.97 0.86
124 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
125 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
126 INT140794 Gene_expression of Smad3 22 0.64 9.41 0.83
127 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
128 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
129 INT192156 Negative_regulation of Col1a1 6 0.39 3.92 0.8
130 INT267095 Regulation of Gene_expression of Smad2 3 0.44 1.77 0.8
131 INT139323 Positive_regulation of Negative_regulation of Tgfb1 1 0.45 0 0.79
132 INT14871 Binding of TGFB3 3 0.13 1.2 0.78
133 INT93737 Gene_expression of Tgfb2 2 0.03 1.16 0.77
134 INT93736 Positive_regulation of Gene_expression of Tgfb2 2 0.02 1.16 0.77
135 INT291617 Negative_regulation of Transcription of TGFB1 2 0.15 0.61 0.76
136 INT137007 Gene_expression of SMAD2 6 0.75 2.53 0.75
137 INT90790 Regulation of Localization of Tgfb1 2 0.29 0.46 0.75
138 INT265318 Negative_regulation of Gene_expression of Smad2 8 0.26 2.16 0.72
139 INT172960 Negative_regulation of Gene_expression of Smad4 7 0.39 5.88 0.71
140 INT269896 Positive_regulation of Gene_expression of Smad2 9 0.40 2.15 0.69
141 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
142 INT337046 Positive_regulation of Binding of Tgfb1 1 0.30 1.1 0.69
143 INT121302 Positive_regulation of Localization of Tgfb1 5 0.07 1.91 0.67
144 INT89520 Regulation of COL1A1 8 0.32 3.21 0.66
145 INT114909 Negative_regulation of Localization of TGFB1 5 0.36 1.37 0.66
146 INT137009 Negative_regulation of Gene_expression of SMAD2 4 0.42 1.76 0.66
147 INT268377 Phosphorylation of SMAD2 7 0.80 0.85 0.65
148 INT115297 Positive_regulation of TGFB2 4 0.29 1.91 0.65
149 INT302664 Positive_regulation of SMAD2 2 0.49 0.85 0.64
150 INT111891 Regulation of Transcription of Tgfb1 1 0.04 0.68 0.64
151 INT243616 Positive_regulation of Transcription of Twist1 6 0.69 2.09 0.6
152 INT114910 Negative_regulation of Positive_regulation of TGFB1 3 0.34 0.92 0.6
153 INT6831 Negative_regulation of Binding of Notch1 1 0.27 0 0.6
154 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
155 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
156 INT173891 Positive_regulation of Phosphorylation of TGFB1 4 0.49 2 0.59
157 INT138140 Protein_catabolism of Tgfb1 2 0.09 0.87 0.59
158 INT54000 Positive_regulation of SNAI1 7 0.49 5.37 0.58
159 INT115292 Regulation of TGFB2 4 0.17 2.79 0.58
160 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
161 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
162 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
163 INT103781 Negative_regulation of Smad4 9 0.42 4.42 0.54
164 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
165 INT130047 Localization of TGFB2 3 0.16 3.65 0.53
166 INT68092 Negative_regulation of Localization of COL1A1 1 0.48 0 0.53
167 INT69683 Positive_regulation of Transcription of Tgfb1 1 0.67 0 0.53
168 INT85808 Localization of BMP2 7 0.77 1.94 0.51
169 INT158889 Gene_expression of Smad2 5 0.65 1.25 0.51
170 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
171 INT8886 Regulation of Transcription of Col1a1 1 0.04 0 0.5
172 INT145301 Regulation of Gene_expression of Bmp2 1 0.32 1.16 0.48
173 INT267837 Gene_expression of TGFB1I1 1 0.15 1.38 0.48
174 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
175 INT140436 Binding of TWIST1 5 0.39 2.34 0.47
176 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
177 INT71019 Negative_regulation of SMAD4 12 0.42 6.88 0.43
178 INT120086 Gene_expression of Bmp2 5 0.27 2.34 0.43
179 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
180 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
181 INT27659 Localization of TGFB3 3 0.29 0.52 0.4
182 INT320812 Positive_regulation of Localization of COL1A1 1 0.05 1.04 0.4
183 INT248931 Positive_regulation of Tgfb2 1 0.03 0 0.4
184 INT231199 Positive_regulation of Localization of Twist1 3 0.50 1.45 0.38
185 INT218691 Phosphorylation of Smad3 1 0.28 3 0.38
186 INT117564 Gene_expression of SMAD4 12 0.71 8.7 0.37
187 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
188 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
189 INT84945 Transcription of BMP2 5 0.61 1.8 0.36
190 INT123578 Negative_regulation of Gene_expression of Snai1 1 0.33 0.5 0.36
191 INT123579 Negative_regulation of Positive_regulation of Snai1 1 0.33 0.51 0.36
192 INT157804 Phosphorylation of Smad3 18 0.77 8.15 0.35
193 INT196026 Positive_regulation of Gene_expression of Bmp2 14 0.69 3.19 0.35
194 INT69680 Positive_regulation of Positive_regulation of Tgfb1 3 0.67 1.04 0.35
195 INT163709 Regulation of Negative_regulation of COL1A1 1 0.29 0.93 0.34
196 INT111230 Transcription of LEF1 3 0.30 1.72 0.33
197 INT135495 Regulation of Positive_regulation of Snai1 1 0.23 0 0.33
198 INT181918 Positive_regulation of SMAD3 6 0.35 2.62 0.31
199 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
200 INT92100 Binding of Smad4 5 0.31 2.23 0.3
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