GO:0010719

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Name negative regulation of epithelial to mesenchymal transition
Categary Process
Go Slim No
Go Link GO:0010719
Unique Molecular Interactions 71
Total Molecular Interactions 104
Total Single Events 371
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of epithelial to mesenchymal transition. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of epithelial to mesenchymal transition. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT313455 Binding of Ppp2ca and Syp 1 0.45 0.68 0.4
2 INT196828 Prkaca Positive_regulation of Ppp2ca 1 0.20 0 0.4
3 INT13077 Tac2 Positive_regulation of NKX2-1 1 0.00 0 0.39
4 INT118285 Binding of EFNA1 and HLA-B 1 0.03 0.29 0.37
5 INT235869 Binding of Slc6a4 and Ppp2ca 1 0.04 0.21 0.31
6 INT235872 Phosphorylation of Ppp2ca Positive_regulation of Slc37a4 1 0.00 0.15 0.31
7 INT235886 Ppp2ca Positive_regulation of Slc37a4 1 0.00 0.15 0.3
8 INT196825 Prkaca Positive_regulation of Phosphorylation of Ppp2ca 1 0.20 0 0.29
9 INT196831 Positive_regulation of Prkaca Positive_regulation of Ppp2ca 1 0.20 0 0.29
10 INT196814 Negative_regulation of Prkaca Positive_regulation of Ppp2ca 1 0.17 0 0.29
11 INT313446 Syp Regulation of Ppp2ca 1 0.58 0.62 0.26
12 INT342164 Binding of Csf2 and Nkx2-1 1 0.01 0.52 0.26
13 INT90280 Binding of Ppp1cc and Ppp2ca 1 0.34 0.22 0.22
14 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2
15 INT313449 Siglec1 Regulation of Ppp2ca 1 0.03 0.61 0.17
16 INT235883 Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
17 INT235879 Regulation of Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
18 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14
19 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14
20 INT196827 Phosphorylation of Prkaca Positive_regulation of Ppp2ca 1 0.18 0 0.11
21 INT196819 Prkaca Positive_regulation of Binding of Ppp2ca 1 0.20 0 0.11
22 INT313430 Syp Positive_regulation of Ppp2ca 1 0.66 0.08 0.09
23 INT313447 Ppp2ca Regulation of Phosphorylation of Syp 1 0.43 0 0.08
24 INT134837 TGFB1 Regulation of SMAD7 1 0.34 0.68 0.08
25 INT134833 TGFB1 Regulation of Gene_expression of SMAD7 1 0.34 0.69 0.08
26 INT313469 Ppp2ca Regulation of Phosphorylation of Siglec1 1 0.06 0 0.08
27 INT134838 TGFB1 Positive_regulation of SMAD7 1 0.52 0.79 0.08
28 INT196810 Binding of Prkaca and Ppp2ca 1 0.14 0 0.07
29 INT313463 Ppp2ca Regulation of Syp 1 0.43 0.6 0.06
30 INT313462 Syp Positive_regulation of Binding of Ppp2ca 1 0.47 0 0.04
31 INT313464 Negative_regulation of Ppp2ca Positive_regulation of Phosphorylation of Mapk1 1 0.09 0 0.03
32 INT313445 53T Regulation of Ppp2ca 1 0.00 0 0.03
33 INT314869 Binding of Gdf11 and Tgfbr3 1 0.29 0.14 0
34 INT262169 Binding of Foxa2 and Nr1i2 1 0.17 0.33 0
35 INT235649 TP73 Regulation of EFNA1 1 0.09 0.97 0
36 INT262183 Foxa2 Positive_regulation of Gene_expression of Hmgcs2 1 0.10 0.22 0
37 INT314693 Binding of TBX2 and TBX5 1 0.16 0.84 0
38 INT293982 MYC Negative_regulation of SFRP1 1 0.21 0.62 0
39 INT314871 Binding of Tgfbr3 and Atoh7 1 0.33 0.09 0
40 INT134836 Binding of SMAD7 and YAP1 1 0.53 0.89 0
41 INT235648 Binding of EFNA1 and EPHA2 1 0.23 1.3 0
42 INT212409 Binding of Efna1 and Epha1 1 0.02 0.39 0
43 INT331611 NKX2-1 Regulation of Transcription of SFTPB 1 0.01 0.49 0
44 INT313457 Ppp2ca Regulation of Th 1 0.36 0 0
45 INT269954 Sox17 Regulation of Gene_expression of Foxa2 1 0.43 0 0
46 INT269933 Foxa2 Regulation of Gene_expression of Foxj1 1 0.27 0 0
47 INT235650 TP53 Regulation of EFNA1 1 0.06 0.97 0
48 INT300438 Efna1 Negative_regulation of Phosphorylation of Kdr 1 0.42 0.66 0
49 INT313465 Syp Regulation of Regulation of Ppp2ca 1 0.26 0.56 0
50 INT313426 Positive_regulation of Ppp2ca Positive_regulation of Bax 1 0.46 0.36 0
51 INT235646 TP63 Regulation of EFNA1 1 0.09 0.97 0
52 INT269941 Sox17 Regulation of Gene_expression of Foxa1 1 0.56 0 0
53 INT269917 Foxa1 Regulation of Gene_expression of Scgb1a1 1 0.24 0 0
54 INT351675 Efna1 Positive_regulation of Epha2 1 0.05 0.68 0
55 INT242102 Nkx2-1 Regulation of Gene_expression of Ttf1 1 0.00 1.55 0
56 INT315194 Binding of SFRP1 and Slc10a1 1 0.02 8.85 0
57 INT338184 Binding of PCa and HPN 1 0.02 0.79 0
58 INT183721 HPN Positive_regulation of MYO7A 1 0.02 1.55 0
59 INT313431 Positive_regulation of Binding of Ppp2ca and Gopc 1 0.11 0.34 0
60 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0
61 INT269939 Foxa1 Regulation of Gene_expression of Foxj1 1 0.26 0 0
62 INT313456 Binding of Ppp2ca and Gopc 1 0.08 0.68 0
63 INT342439 PPP2CA Negative_regulation of PRMT1 1 0.12 0.63 0
64 INT315187 Binding of SFRP1 and COPD 1 0.01 4.47 0
65 INT314853 Binding of Cdc7 and Tgfbr3 1 0.24 0.09 0
66 INT269927 Foxa2 Regulation of Gene_expression of Scgb1a1 1 0.26 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of epithelial to mesenchymal transition. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of epithelial to mesenchymal transition. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT196782 Positive_regulation of Ppp2ca 32 0.61 1.89 4.33
2 INT90277 Negative_regulation of Ppp2ca 15 0.41 4.04 4.02
3 INT196779 Phosphorylation of Ppp2ca 28 0.72 1.86 3.25
4 INT90272 Gene_expression of Ppp2ca 18 0.68 4.69 2.08
5 INT13075 Binding of NKX2-1 6 0.05 0.12 2.08
6 INT158442 Gene_expression of Nkx2-1 21 0.59 8.47 1.99
7 INT118286 Binding of EFNA1 3 0.21 4.95 1.55
8 INT111162 Negative_regulation of EFNA1 2 0.03 2.78 1.45
9 INT144805 Regulation of Negative_regulation of Ppp2ca 1 0.28 0.24 1.38
10 INT196785 Regulation of Ppp2ca 5 0.54 2.1 1.17
11 INT78266 Localization of NKX2-1 2 0.73 0.16 1.12
12 INT15040 Gene_expression of NKX2-1 8 0.65 3.95 1.02
13 INT90278 Localization of Ppp2ca 4 0.66 1.12 0.94
14 INT47039 Regulation of SFRP1 14 0.62 7.44 0.92
15 INT196754 Binding of Ppp2ca 5 0.37 0.42 0.89
16 INT13074 Positive_regulation of NKX2-1 4 0.19 0.86 0.87
17 INT15039 Negative_regulation of NKX2-1 3 0.21 0 0.72
18 INT196753 Negative_regulation of Phosphorylation of Ppp2ca 3 0.37 0.52 0.7
19 INT111161 Positive_regulation of EFNA1 6 0.40 4.62 0.68
20 INT196742 Positive_regulation of Positive_regulation of Ppp2ca 4 0.44 0.05 0.68
21 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63
22 INT296253 Negative_regulation of Gene_expression of Ppp2ca 3 0.41 1.71 0.62
23 INT196765 Positive_regulation of Gene_expression of Ppp2ca 4 0.44 1.05 0.6
24 INT135366 Localization of SFRP1 4 0.75 1.82 0.47
25 INT134840 Gene_expression of SMAD7 1 0.74 2.74 0.31
26 INT111164 Positive_regulation of Efna1 1 0.02 0.83 0.28
27 INT196761 Regulation of Positive_regulation of Ppp2ca 2 0.40 0.05 0.22
28 INT196763 Positive_regulation of Regulation of Ppp2ca 1 0.30 0 0.21
29 INT196759 Negative_regulation of Negative_regulation of Ppp2ca 2 0.30 0.17 0.2
30 INT196770 Negative_regulation of Positive_regulation of Ppp2ca 1 0.27 0 0.16
31 INT200943 Negative_regulation of PPP2CA 1 0.10 0.13 0.14
32 INT24324 Regulation of NKX2-1 1 0.03 0.1 0.13
33 INT313409 Positive_regulation of Phosphorylation of Ppp2ca 1 0.39 0.16 0.11
34 INT313423 Positive_regulation of Localization of Ppp2ca 1 0.44 0.12 0.1
35 INT183722 Gene_expression of HPN 3 0.37 1.63 0.08
36 INT235659 Gene_expression of EFNA1 1 0.45 22.92 0.06
37 INT206866 Positive_regulation of SFRP1 7 0.51 3.97 0.05
38 INT287913 Positive_regulation of Gene_expression of SFRP1 2 0.25 2.12 0.05
39 INT308287 Positive_regulation of HPN 1 0.39 0.48 0.05
40 INT313406 Positive_regulation of Binding of Ppp2ca 1 0.44 0 0.04
41 INT313421 Regulation of Phosphorylation of Ppp2ca 1 0.40 0 0.03
42 INT350515 Transcription of SMAD7 1 0.07 0.38 0.03
43 INT262960 Gene_expression of TBX5 1 0.23 0.09 0.03
44 INT226288 Negative_regulation of SFRP1 6 0.43 4.45 0
45 INT200834 Positive_regulation of Foxa2 2 0.32 0.08 0
46 INT313407 Regulation of Regulation of Ppp2ca 1 0.24 0.56 0
47 INT242099 Binding of Nkx2-1 1 0.02 1.15 0
48 INT291288 Binding of HPN 1 0.09 0.3 0
49 INT166121 Binding of SMAD7 1 0.30 0.39 0
50 INT342452 Gene_expression of PPP2CA 1 0.20 0.49 0
51 INT212399 Binding of Efna1 1 0.47 0.2 0
52 INT269871 Gene_expression of Foxa1 1 0.61 0 0
53 INT315189 Binding of SFRP1 1 0.15 2.96 0
54 INT226287 Regulation of Gene_expression of SFRP1 1 0.38 0.37 0
55 INT235656 Positive_regulation of Gene_expression of EFNA1 1 0.40 8.86 0
56 INT212401 Regulation of Gene_expression of Efna1 1 0.44 0 0
57 INT262045 Phosphorylation of Foxa2 1 0.34 0.08 0
58 INT314839 Binding of Tgfbr3 1 0.42 0.09 0
59 INT342450 Positive_regulation of PPP2CA 1 0.15 1.07 0
60 INT308286 Negative_regulation of HPN 1 0.36 0.19 0
61 INT235657 Localization of EFNA1 1 0.43 0.9 0
62 INT262071 Binding of Foxa2 1 0.15 0.68 0
63 INT314836 Gene_expression of Tgfbr3 1 0.59 0.09 0
64 INT226286 Negative_regulation of Gene_expression of SFRP1 1 0.31 0.7 0
65 INT262084 Negative_regulation of Binding of Foxa2 1 0.18 0.23 0
66 INT294017 Negative_regulation of Localization of SFRP1 1 0.32 0.47 0
67 INT262125 Negative_regulation of Foxa2 1 0.18 0.08 0
68 INT207714 Positive_regulation of Gene_expression of HPN 1 0.33 0.57 0
69 INT212389 Gene_expression of Efna1 1 0.75 0 0
70 INT269888 Gene_expression of Foxa2 1 0.65 0 0
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