GO:0010736

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Name serum response element binding
Categary Function
Go Slim No
Go Link GO:0010736
Unique Molecular Interactions 25
Total Molecular Interactions 30
Total Single Events 155
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for serum response element binding. They are ordered first by their pain relevance and then by number of times they were reported for serum response element binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
2 INT89877 Pdyn Positive_regulation of Nkx2-5 1 0.11 0 0.64
3 INT93833 Binding of Fos and Srf 1 0.00 0 0.3
4 INT109067 Pdyn Positive_regulation of Gene_expression of NKX2-5 1 0.01 0 0.29
5 INT93832 Binding of Elk1 and Srf 1 0.00 0 0.29
6 INT208938 Positive_regulation of Tacr1 Positive_regulation of Nkx2-5 1 0.17 0 0.1
7 INT208943 Nfkb1 Positive_regulation of Nkx2-5 1 0.11 0.38 0.08
8 INT216130 SRF Positive_regulation of Gene_expression of EGR1 1 0.49 0.32 0.07
9 INT216129 SRF Positive_regulation of Gene_expression of FOS 1 0.28 0.32 0.07
10 INT208945 Nkx2-5 Positive_regulation of Gene_expression of Nppa 1 0.03 0.33 0.05
11 INT319558 Positive_regulation of Creb1 Regulation of Srf 1 0.31 0.06 0.04
12 INT319559 Creb1 Regulation of Srf 1 0.28 0.06 0.04
13 INT305383 Binding of NKX2-5 and FLNA 1 0.10 0.7 0.04
14 INT132849 Homer1 Regulation of Srf 1 0.01 0.15 0
15 INT190632 Binding of Srf and Yy1 1 0.20 0.14 0
16 INT225590 Ncoa6 Regulation of Srf 1 0.08 0.21 0
17 INT272520 Gene_expression of Dmpk Positive_regulation of Positive_regulation of Nkx2-5 1 0.02 0.43 0
18 INT272521 Binding of DMPK and Nkx2-5 1 0.01 0.42 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for serum response element binding. They are ordered first by their pain relevance and then by number of times they were reported in serum response element binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
2 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
3 INT89865 Gene_expression of Nkx2-5 14 0.75 2.99 1.58
4 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03
5 INT135032 Negative_regulation of SRF 1 0.49 0 1.03
6 INT161716 Localization of Nkx2-5 2 0.74 2.17 1.02
7 INT109075 Positive_regulation of Transcription of NKX2-5 1 0.67 0 1.02
8 INT109074 Transcription of NKX2-5 1 0.69 0 1.01
9 INT26531 Regulation of Srf 3 0.18 0.62 0.9
10 INT109062 Gene_expression of NKX2-5 7 0.75 3.31 0.82
11 INT45293 Transcription of Srf 2 0.47 0.79 0.76
12 INT45489 Gene_expression of SRF 5 0.77 3.29 0.71
13 INT89861 Negative_regulation of Nkx2-5 3 0.19 0.12 0.63
14 INT45292 Negative_regulation of Transcription of Srf 1 0.06 0.65 0.59
15 INT89869 Negative_regulation of Gene_expression of Nkx2-5 1 0.41 0 0.56
16 INT305390 Negative_regulation of NKX2-5 2 0.37 2.24 0.49
17 INT18821 Positive_regulation of Gene_expression of Srf 2 0.35 0.63 0.31
18 INT7610 Localization of Srf 3 0.67 0.98 0.27
19 INT208915 Positive_regulation of Nkx2-5 3 0.29 1.02 0.25
20 INT305392 Binding of NKX2-5 1 0.22 0.93 0.21
21 INT208925 Positive_regulation of Localization of Nkx2-5 1 0.21 0.14 0.16
22 INT89766 Binding of SRF 1 0.17 0.89 0.15
23 INT89767 Positive_regulation of Binding of SRF 1 0.23 0.89 0.15
24 INT146415 Regulation of Nkx2-5 3 0.44 0.91 0.13
25 INT208922 Transcription of Nkx2-5 2 0.29 0.36 0.1
26 INT323415 Regulation of NKX2-5 1 0.39 0.71 0.1
27 INT208917 Positive_regulation of Transcription of Nkx2-5 1 0.21 0 0.1
28 INT323416 Localization of NKX2-5 1 0.65 1.75 0.1
29 INT208918 Positive_regulation of Gene_expression of Nkx2-5 3 0.23 0.48 0.09
30 INT22789 Binding of Srf 1 0.37 0.07 0.07
31 INT305387 Positive_regulation of Gene_expression of NKX2-5 1 0.31 0.72 0.07
32 INT22790 Positive_regulation of Binding of Srf 1 0.50 0.07 0.07
33 INT190544 Transcription of Srf 1 0.19 0.43 0.06
34 INT190570 Localization of Srf 1 0.20 0.49 0.06
35 INT225411 Positive_regulation of Srf 1 0.05 0.27 0.03
36 INT268102 Transcription of SRF 1 0.53 0.85 0.03
37 INT225413 Binding of Srf 1 0.10 0.27 0.03
38 INT157800 Gene_expression of Srf 2 0.45 0.88 0
39 INT105753 Positive_regulation of Gene_expression of SRF 1 0.01 0.13 0
40 INT105752 Positive_regulation of SRF 1 0.01 0.13 0
41 INT268104 Negative_regulation of Gene_expression of SRF 1 0.38 0.16 0
42 INT213446 Regulation of Gene_expression of SRF 1 0.22 0.71 0
43 INT225408 Negative_regulation of Srf 1 0.05 0.39 0
44 INT157799 Negative_regulation of Gene_expression of Srf 1 0.18 0.07 0
45 INT157794 Phosphorylation of Srf 1 0.26 0.07 0
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