GO:0010738

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Name regulation of protein kinase A signaling cascade
Categary Process
Go Slim No
Go Link GO:0010738
Unique Molecular Interactions 24
Total Molecular Interactions 30
Total Single Events 265
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of protein kinase A signaling cascade. They are ordered first by their pain relevance and then by number of times they were reported for regulation of protein kinase A signaling cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149925 Negative_regulation of Cpox Negative_regulation of Gene_expression of Pde4d 1 0.01 0.39 0.84
2 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
3 INT273350 Pde7a Positive_regulation of Localization of Pde4d 1 0.33 1.35 0.49
4 INT287794 Binding of IGHG3 and AIP 1 0.05 2.8 0.24
5 INT110384 Binding of Prkaca and Akap11 1 0.08 0.31 0.2
6 INT219597 Prkaca Positive_regulation of Pde4d 1 0.29 0 0.15
7 INT219599 Pde4d Regulation of Prkaca 1 0.28 0 0.12
8 INT167040 Binding of Aip and Drb1 1 0.10 0.54 0.1
9 INT167041 Binding of HLA-A and Aip 1 0.02 0.54 0.1
10 INT219600 Pde4d Regulation of Binding of Prkaca 1 0.28 0 0.09
11 INT219602 Binding of Prkaca and Pde4d 1 0.23 0 0.09
12 INT145987 Binding of CTLA4 and Aip 1 0.08 0.61 0.09
13 INT273353 Pde4d Regulation of Gene_expression of Twist1 1 0.26 0.25 0.05
14 INT308432 Binding of PDE4A and Aip 1 0.05 3.1 0.05
15 INT329996 Binding of SGCD and AKAP6 1 0.37 0.46 0
16 INT219596 Binding of Pde4a and Pde4d 1 0.28 0.31 0
17 INT308425 Binding of Pde2a and Aip 1 0.04 1.37 0
18 INT329995 Binding of KCNMA1 and AKAP6 1 0.40 0.48 0
19 INT161823 Positive_regulation of Binding of Igha and Aip 1 0.01 0.16 0
20 INT161822 Binding of Igha and Aip 1 0.00 0.16 0
21 INT329992 Binding of SNRNP70 and AKAP6 1 0.03 0.95 0
22 INT161825 Binding of IgG and Aip 1 0.01 0.32 0
23 INT308426 Binding of Pde4a and Aip 1 0.02 0.89 0
24 INT161824 Positive_regulation of Binding of and Aip 1 0.01 0.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of protein kinase A signaling cascade. They are ordered first by their pain relevance and then by number of times they were reported in regulation of protein kinase A signaling cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121801 Binding of Aip 18 0.36 24.1 5.26
2 INT105775 Gene_expression of Pde4d 31 0.78 4.18 5.21
3 INT112989 Gene_expression of AIP 3 0.56 25.4 4.23
4 INT148671 Gene_expression of Aip 26 0.63 24.32 3.91
5 INT120062 Binding of AIP 4 0.42 28.86 3.91
6 INT3564 Positive_regulation of Aip 11 0.58 15.38 3.62
7 INT79399 Gene_expression of Pde4d 6 0.70 2.83 2.51
8 INT107489 Negative_regulation of Pde4d 3 0.42 0 2.47
9 INT107490 Positive_regulation of Pde4d 3 0.69 0.07 2.13
10 INT105776 Negative_regulation of Gene_expression of Pde4d 5 0.59 2.2 2.01
11 INT287798 Localization of AIP 1 0.63 5.96 1.31
12 INT114091 Negative_regulation of Aip 6 0.48 4.16 1.3
13 INT135924 Positive_regulation of Gene_expression of Pde4d 2 0.59 0 1.28
14 INT149924 Negative_regulation of Gene_expression of Pde4d 1 0.26 0.81 1.24
15 INT287799 Positive_regulation of Gene_expression of AIP 1 0.42 7.39 1.19
16 INT219589 Binding of Pde4d 13 0.47 0.51 1.01
17 INT219568 Positive_regulation of Pde4d 9 0.49 1.74 1
18 INT274238 Positive_regulation of AIP 2 0.42 8.14 0.97
19 INT219578 Negative_regulation of Pde4d 3 0.46 2.95 0.8
20 INT135923 Regulation of Gene_expression of Pde4d 2 0.44 0 0.8
21 INT118753 Regulation of Negative_regulation of Pde4d 1 0.02 0 0.8
22 INT219580 Localization of Pde4d 5 0.73 2.07 0.64
23 INT154613 Regulation of Aip 5 0.21 3.86 0.55
24 INT79397 Positive_regulation of Gene_expression of Pde4d 1 0.45 0.2 0.55
25 INT154449 Positive_regulation of Gene_expression of Aip 2 0.43 2.88 0.52
26 INT219573 Positive_regulation of Localization of Pde4d 2 0.49 1.39 0.5
27 INT219565 Regulation of Pde4d 3 0.44 0.5 0.39
28 INT273330 Positive_regulation of Negative_regulation of Pde4d 1 0.39 1.25 0.35
29 INT144179 Localization of Aip 4 0.61 2.59 0.33
30 INT287800 Positive_regulation of Positive_regulation of AIP 1 0.42 2.15 0.3
31 INT273341 Transcription of Pde4d 2 0.54 0.68 0.24
32 INT356135 Positive_regulation of Binding of Aip 1 0.09 0.81 0.24
33 INT273336 Regulation of Negative_regulation of Pde4d 1 0.35 0.68 0.24
34 INT356136 Negative_regulation of Localization of Aip 1 0.08 0.88 0.23
35 INT167038 Binding of Aip 2 0.21 2.13 0.19
36 INT287797 Phosphorylation of AIP 1 0.78 2.04 0.16
37 INT219593 Regulation of Binding of Pde4d 1 0.44 0 0.13
38 INT219574 Phosphorylation of Pde4d 1 0.79 0.33 0.1
39 INT112990 Negative_regulation of AIP 1 0.10 0.59 0.09
40 INT167037 Regulation of Aip 1 0.25 0.71 0.09
41 INT329999 Binding of AKAP6 1 0.36 0.91 0.07
42 INT219585 Positive_regulation of Positive_regulation of Pde4d 1 0.43 0 0.06
43 INT308415 Negative_regulation of Transcription of Aip 1 0.48 0.82 0.03
44 INT308414 Negative_regulation of Gene_expression of Aip 1 0.48 0.82 0.03
45 INT248265 Regulation of Pde4d 1 0.21 0.87 0
46 INT329998 Localization of AKAP6 1 0.72 0.26 0
47 INT330002 Gene_expression of AKAP6 1 0.75 0.11 0
48 INT219570 Negative_regulation of Positive_regulation of Pde4d 1 0.42 0 0
49 INT219575 Positive_regulation of Binding of Pde4d 1 0.49 0 0
50 INT308416 Regulation of Gene_expression of Aip 1 0.37 0.77 0
51 INT308417 Transcription of Aip 1 0.59 0.82 0
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