GO:0010740

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Name positive regulation of intracellular protein kinase cascade
Categary Process
Go Slim No
Go Link GO:0010740
Unique Molecular Interactions 676
Total Molecular Interactions 1092
Total Single Events 7998
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of intracellular protein kinase cascade. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of intracellular protein kinase cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
2 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
3 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
4 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
5 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
6 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33
7 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
8 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
9 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
10 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
11 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
12 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
13 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
14 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
15 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
16 INT143915 Src Regulation of Rbm39 1 0.03 0.18 0.99
17 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
18 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
19 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
20 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
21 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
22 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
23 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
24 INT66334 Fgf2 Regulation of Fgf1 1 0.37 0.17 0.9
25 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
26 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86
27 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84
28 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
29 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
30 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
31 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82
32 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82
33 INT21233 Ngf Regulation of Fgf1 1 0.46 0.09 0.79
34 INT187229 Binding of Tnfsf11 and Insrr 1 0.00 2.06 0.78
35 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77
36 INT135180 IL1B Positive_regulation of Gene_expression of TNFSF11 2 0.76 1.73 0.75
37 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
38 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
39 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
40 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
41 INT148453 Gene_expression of Inhbe Positive_regulation of Src 1 0.06 0.68 0.72
42 INT187231 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.18 1.8 0.71
43 INT107910 Binding of Tnfrsf11b and Tnfsf11 6 0.30 5.88 0.7
44 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
45 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
46 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
47 INT187220 Il11 Positive_regulation of Gene_expression of Tnfsf11 1 0.13 0.86 0.69
48 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
49 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
50 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
51 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
52 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
53 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
54 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
55 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
56 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
57 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
58 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
59 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
60 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
61 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
62 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
63 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
64 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
65 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
66 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
67 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
68 INT209885 TNFSF11 Positive_regulation of TNFRSF11A 3 0.56 3.41 0.55
69 INT254279 Il13 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54
70 INT254280 Il4 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54
71 INT194918 Csf2 Positive_regulation of Gene_expression of VEGFA 1 0.02 0.85 0.52
72 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
73 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51
74 INT187227 Vip Negative_regulation of Gene_expression of Tnfsf11 1 0.35 1.23 0.51
75 INT207394 IL1B Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.95 0.51
76 INT160203 Prkcc Positive_regulation of Src 1 0.02 0 0.51
77 INT98737 Src Negative_regulation of Tk1 1 0.22 0.15 0.5
78 INT127430 VEGFA Negative_regulation of Gene_expression of TIMP1 1 0.43 0.6 0.5
79 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
80 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49
81 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49
82 INT207395 TNF Regulation of Gene_expression of Tnfsf11 1 0.11 0.91 0.49
83 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
84 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
85 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48
86 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48
87 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48
88 INT231732 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48
89 INT231733 Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48
90 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47
91 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
92 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
93 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
94 INT224698 Il17a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
95 INT224699 Il18 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
96 INT224451 Il1 Positive_regulation of Gene_expression of VEGFA 1 0.10 1.08 0.45
97 INT66335 Fgf1 Regulation of Fgf2 1 0.10 0.08 0.45
98 INT224434 TNF Positive_regulation of VEGFA 1 0.10 2.04 0.44
99 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43
100 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43
101 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
102 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
103 INT153720 Binding of VEGFA and Pscs 1 0.32 3.12 0.41
104 INT346130 Il17a Positive_regulation of Gene_expression of TNFSF11 1 0.08 0.61 0.41
105 INT205567 Regulation of Binding of Fgf1 and Chat 1 0.29 0.28 0.41
106 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41
107 INT205566 Binding of Fgf1 and Chat 1 0.24 0.28 0.41
108 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39
109 INT285205 Binding of VEGFA and SLEB1 1 0.05 5.12 0.38
110 INT342623 Binding of VEGFA and Col18a1 1 0.02 1.15 0.37
111 INT342606 Binding of MMP14 and VEGFA 1 0.08 1.16 0.37
112 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
113 INT143917 Binding of Src and Arrb2 1 0.27 0.07 0.37
114 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
115 INT277355 VEGFA Regulation of Trerf1 1 0.08 1.17 0.37
116 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
117 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
118 INT277352 Gene_expression of VEGFA Regulation of Trerf1 1 0.08 1.16 0.37
119 INT143918 Binding of Src and Rbm39 1 0.02 0.07 0.36
120 INT329449 IL17A Regulation of Gene_expression of Vegfa 1 0.28 0.63 0.36
121 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
122 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
123 INT263382 Src Regulation of Trib3 1 0.00 0.29 0.35
124 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34
125 INT352231 VEGFA Negative_regulation of Cntf 1 0.04 0.22 0.34
126 INT352230 VEGFA Negative_regulation of Gene_expression of Cntf 1 0.04 0.22 0.34
127 INT352232 VEGFA Negative_regulation of Vegfa 1 0.02 0.21 0.34
128 INT210597 Negative_regulation of Binding of TNFSF11 and TNFRSF11A 3 0.26 5.66 0.33
129 INT165764 Tnfsf11 Positive_regulation of Mapk3 1 0.17 1.08 0.33
130 INT181896 TNF Regulation of TEK 1 0.03 1.21 0.33
131 INT249490 Phosphorylation of Ephb2 Positive_regulation of Src 1 0.17 0.15 0.33
132 INT110691 Lta Positive_regulation of Gene_expression of VEGFA 1 0.24 0.48 0.33
133 INT295717 VEGFA Regulation of MMP9 1 0.01 0.98 0.33
134 INT165765 Tnfsf11 Positive_regulation of Nfkb1 1 0.01 1.07 0.33
135 INT165763 Tnfsf11 Positive_regulation of Phosphorylation of Mapk3 1 0.40 1.08 0.33
136 INT329448 IL17A Positive_regulation of Gene_expression of Vegfa 1 0.45 0.59 0.32
137 INT187223 Il1 Positive_regulation of Gene_expression of Tnfsf11 1 0.09 0.64 0.32
138 INT188804 S100a8 Positive_regulation of Gene_expression of Tnfsf11 1 0.00 0.7 0.31
139 INT249480 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Src 1 0.22 0.23 0.31
140 INT144500 CCL3 Positive_regulation of Gene_expression of Tnfsf11 1 0.77 1.62 0.31
141 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3
142 INT224422 Regulation of Binding of NFKB2 and TNFSF11 1 0.13 0.69 0.3
143 INT210953 Binding of VEGFA and Csf2 1 0.00 0.47 0.3
144 INT281797 Positive_regulation of Chrna4 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.43 0.3
145 INT224418 Binding of NFKB2 and TNFSF11 1 0.11 0.68 0.3
146 INT163903 Binding of EFNB1 and Src 1 0.03 0.56 0.29
147 INT266800 Dlst Positive_regulation of Localization of VEGFA 1 0.02 0.88 0.29
148 INT254353 Binding of VEGFA and MMRN1 1 0.00 0.81 0.28
149 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27
150 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27
151 INT103156 Tnf Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.94 0.27
152 INT287699 TNF Regulation of Binding of VEGFA 1 0.02 0.46 0.27
153 INT318551 Binding of VEGFA and Adamts1 1 0.13 1.13 0.27
154 INT285238 EGF Positive_regulation of VEGFA 1 0.01 1.55 0.27
155 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
156 INT248318 RETN Regulation of VEGFA 1 0.00 0.43 0.26
157 INT109538 Lox Negative_regulation of Transcription of VEGFA 1 0.30 0.69 0.26
158 INT260423 IFNA1 Positive_regulation of Gene_expression of VEGFA 1 0.01 1.28 0.26
159 INT254359 IL1B Positive_regulation of Localization of VEGFA 1 0.01 0.87 0.26
160 INT103152 TNF Positive_regulation of Positive_regulation of VEGFA 1 0.09 0.93 0.26
161 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26
162 INT126887 Protein_catabolism of SP4 Negative_regulation of Gene_expression of VEGFA 1 0.15 0.49 0.26
163 INT266803 Dlst Positive_regulation of VEGFA 1 0.01 0.96 0.25
164 INT109539 Lox Negative_regulation of VEGFA 1 0.40 0.68 0.25
165 INT145660 Zfp329 Positive_regulation of Gene_expression of VEGFA 1 0.00 0.51 0.25
166 INT241401 VEGFA Positive_regulation of Gene_expression of Gopc 1 0.11 0.85 0.25
167 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
168 INT98631 Negative_regulation of VEGFA Positive_regulation of EGR1 1 0.44 0.18 0.24
169 INT98630 VEGFA Positive_regulation of EGR1 1 0.52 0.18 0.24
170 INT304323 VEGFA Positive_regulation of Gene_expression of Ptger2 1 0.27 0.16 0.23
171 INT118840 VEGFA Regulation of Positive_regulation of Mb 1 0.05 0.36 0.23
172 INT163403 VEGFA Positive_regulation of MMP2 1 0.52 0.13 0.23
173 INT323436 VEGFA Regulation of Kdr 1 0.03 0.77 0.23
174 INT304321 Ptger4 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.59 0.23
175 INT304324 VEGFA Positive_regulation of Gene_expression of Ptger4 1 0.27 0.16 0.23
176 INT254351 Binding of ANGPT2 and TEK 1 0.04 0.87 0.22
177 INT303029 Binding of TEK and Angpt1 1 0.26 1.82 0.22
178 INT245866 Binding of VEGFA and Fgf1 1 0.07 0.52 0.22
179 INT118838 Gene_expression of Vegfa Positive_regulation of Gene_expression of Mb 1 0.44 0.4 0.22
180 INT318189 MUC5AC Regulation of Gene_expression of VEGFA 1 0.21 1.17 0.22
181 INT137611 Crh Positive_regulation of Vegfa 1 0.43 0.49 0.21
182 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
183 INT137612 Crh Positive_regulation of Positive_regulation of Vegfa 1 0.43 0.43 0.21
184 INT250853 Binding of Fgf1 and Mtpn 1 0.00 0.28 0.21
185 INT114837 Il1b Negative_regulation of Vegfa 1 0.26 3.04 0.21
186 INT163096 Tlr2 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.16 0.21
187 INT301279 Tnfsf11 Regulation of Gene_expression of Mmp9 1 0.13 0.34 0.21
188 INT116469 VEGFA Positive_regulation of Amfr 1 0.01 1.39 0.21
189 INT116468 VEGFA Positive_regulation of Akt1 1 0.04 1.39 0.21
190 INT171973 Tnfsf11 Positive_regulation of Gene_expression of Il1 1 0.06 0.21 0.21
191 INT171972 Tnfsf11 Positive_regulation of Gene_expression of Il6 1 0.08 0.21 0.21
192 INT116466 Vegfa Positive_regulation of Amfr 1 0.07 1.41 0.21
193 INT301281 Tnfsf11 Regulation of Gene_expression of Clec5a 1 0.22 0.34 0.21
194 INT137610 Crh Positive_regulation of Localization of Vegfa 1 0.43 0.49 0.21
195 INT188801 Il6 Positive_regulation of Positive_regulation of Tnfsf11 1 0.06 0.46 0.21
196 INT345196 Lpar2 Positive_regulation of Gene_expression of VEGFA 1 0.08 2.14 0.2
197 INT174861 Binding of FGF2 and VEGFA 1 0.34 0.59 0.2
198 INT236405 Mthfs Regulation of Gene_expression of VEGFA 1 0.00 0.25 0.2
199 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
200 INT189553 DCN Negative_regulation of Transcription of VEGFA 1 0.06 0.78 0.2

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of intracellular protein kinase cascade. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of intracellular protein kinase cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
3 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
4 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
5 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
6 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66
7 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
8 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
9 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
10 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
11 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
12 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
13 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
14 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53
15 INT130867 Gene_expression of TNFSF11 106 0.77 45.15 10.34
16 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
17 INT119729 Binding of Tnfsf11 31 0.35 24.02 7.45
18 INT104207 Positive_regulation of Gene_expression of Tnfsf11 43 0.69 25.8 7.35
19 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
20 INT136555 Negative_regulation of Tnfsf11 31 0.55 22.23 6.23
21 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
22 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
23 INT100222 Binding of Src 9 0.26 5.41 5.37
24 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
25 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
26 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
27 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
28 INT98453 Positive_regulation of Src 19 0.47 7.84 4.62
29 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
30 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
31 INT134646 Gene_expression of Tnfsf11 19 0.69 14.77 4.16
32 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
33 INT48143 Gene_expression of Fgf1 32 0.78 8.2 3.72
34 INT122327 Regulation of Src 6 0.59 0.59 3.6
35 INT137350 Phosphorylation of Src 13 0.45 4.14 3.32
36 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
37 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
38 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
39 INT130865 Positive_regulation of TNFSF11 29 0.69 12.82 2.99
40 INT114702 Gene_expression of Fgf1 34 0.74 17.39 2.96
41 INT93531 Negative_regulation of Gene_expression of Tnfsf11 15 0.43 7.74 2.84
42 INT132846 Localization of Tnfsf11 17 0.69 10.28 2.78
43 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
44 INT225253 Positive_regulation of Phosphorylation of Src 4 0.38 2.36 2.59
45 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43
46 INT81989 Positive_regulation of Tnfsf11 11 0.54 7.57 2.4
47 INT144490 Regulation of Gene_expression of Tnfsf11 14 0.58 14.09 2.39
48 INT93532 Regulation of Tnfsf11 14 0.42 10.75 2.39
49 INT65034 Regulation of Fgf1 7 0.61 2.42 2.34
50 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
51 INT29402 Gene_expression of Src 16 0.74 4.57 2.29
52 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
53 INT176088 Gene_expression of Tek 39 0.65 14.25 2.19
54 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
55 INT136818 Positive_regulation of Phosphorylation of VEGFA 4 0.46 0.81 2.02
56 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92
57 INT249530 Positive_regulation of Positive_regulation of Src 3 0.28 1.32 1.9
58 INT153719 Gene_expression of TEK 10 0.49 9.82 1.88
59 INT130866 Positive_regulation of Gene_expression of TNFSF11 25 0.69 7.11 1.82
60 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
61 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
62 INT146943 Gene_expression of Src 13 0.49 6.65 1.65
63 INT182643 Binding of TNFSF11 15 0.35 13.12 1.61
64 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
65 INT89116 Regulation of Positive_regulation of VEGFA 8 0.43 6.62 1.5
66 INT73816 Positive_regulation of Fgf1 5 0.70 2.31 1.49
67 INT98455 Regulation of Src 4 0.20 1.76 1.48
68 INT162057 Negative_regulation of TNFSF11 14 0.58 9.78 1.46
69 INT63328 Binding of Fgf1 10 0.37 1.5 1.4
70 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
71 INT105551 Transcription of Tnfsf11 6 0.69 4.21 1.38
72 INT92966 Positive_regulation of FGF1 4 0.38 2.25 1.33
73 INT135181 Regulation of Gene_expression of TNFSF11 5 0.61 6.98 1.27
74 INT135186 Negative_regulation of Gene_expression of TNFSF11 10 0.58 2.69 1.25
75 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
76 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
77 INT105552 Positive_regulation of Transcription of Tnfsf11 3 0.31 2.94 1.17
78 INT224429 Regulation of TNFSF11 8 0.61 4.35 1.13
79 INT249522 Positive_regulation of Binding of Src 1 0.22 0.68 1.12
80 INT124167 Regulation of Positive_regulation of Src 2 0.13 0.47 1.1
81 INT210586 Negative_regulation of Positive_regulation of Tnfsf11 3 0.41 1.4 1.02
82 INT132847 Negative_regulation of Localization of Tnfsf11 1 0.32 0.16 1.01
83 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99
84 INT317504 Protein_catabolism of Src 1 0.49 0.13 0.97
85 INT171963 Positive_regulation of Positive_regulation of Tnfsf11 3 0.42 2.44 0.93
86 INT100221 Negative_regulation of Phosphorylation of Src 2 0.24 0.74 0.93
87 INT114704 Positive_regulation of Fgf1 13 0.50 8.89 0.89
88 INT86474 Negative_regulation of Fgf1 6 0.58 0.64 0.88
89 INT211488 Regulation of Binding of VEGFA 5 0.43 3.72 0.83
90 INT94833 Gene_expression of FGF1 4 0.53 2.01 0.81
91 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79
92 INT294998 Positive_regulation of Gene_expression of Tnfsf11 5 0.62 2.98 0.79
93 INT143912 Localization of Src 4 0.48 2.51 0.78
94 INT249506 Regulation of Phosphorylation of Src 1 0.13 0.48 0.77
95 INT143445 Protein_catabolism of VEGFA 12 0.85 4.14 0.72
96 INT298598 Positive_regulation of Positive_regulation of TNFSF11 2 0.38 1.26 0.72
97 INT12443 Regulation of Localization of Vegfa 2 0.20 0 0.72
98 INT165760 Positive_regulation of Binding of Tnfsf11 2 0.36 1.83 0.71
99 INT73815 Localization of Fgf1 10 0.80 1.73 0.69
100 INT185729 Negative_regulation of Gene_expression of Tnfsf11 3 0.52 2.07 0.69
101 INT205171 Localization of TNFSF11 4 0.74 3.94 0.66
102 INT340625 Protein_catabolism of Vegfa 1 0.05 1.61 0.64
103 INT174868 Regulation of Negative_regulation of VEGFA 4 0.43 4.51 0.63
104 INT104233 Positive_regulation of Gene_expression of Fgf1 2 0.63 1.79 0.62
105 INT264991 Positive_regulation of Localization of Tnfsf11 5 0.24 3.22 0.59
106 INT235996 Negative_regulation of Gene_expression of Src 3 0.09 1.29 0.58
107 INT94834 Positive_regulation of Gene_expression of FGF1 2 0.48 1.82 0.56
108 INT143910 Negative_regulation of Positive_regulation of Src 1 0.27 0.14 0.56
109 INT174873 Regulation of Transcription of VEGFA 8 0.43 3.71 0.55
110 INT184690 Transcription of Fgf1 6 0.51 1.97 0.55
111 INT172964 Binding of Vegfa 14 0.47 10.62 0.53
112 INT105677 Binding of Vegfa 7 0.37 5.22 0.51
113 INT117998 Positive_regulation of Gene_expression of Src 4 0.36 1.45 0.51
114 INT207379 Regulation of Negative_regulation of Tnfsf11 2 0.28 1.7 0.5
115 INT249504 Localization of Src 1 0.36 0.32 0.46
116 INT340265 Localization of Tnfsf11 2 0.30 1.65 0.44
117 INT341289 Positive_regulation of Localization of Tnfsf11 1 0.13 1.26 0.44
118 INT247568 Negative_regulation of Negative_regulation of VEGFA 5 0.41 5.35 0.43
119 INT98456 Negative_regulation of Src 17 0.42 8.3 0.42
120 INT137846 Regulation of Tnfsf11 5 0.48 1.62 0.42
121 INT268877 Regulation of Gene_expression of Vegfa 2 0.58 4.73 0.42
122 INT152023 Regulation of Vegfa 4 0.52 3.99 0.41
123 INT159051 Positive_regulation of Transcription of Fgf1 1 0.45 0.71 0.41
124 INT43720 Regulation of Positive_regulation of Vegfa 1 0.03 0.41 0.41
125 INT43722 Positive_regulation of Regulation of Vegfa 1 0.06 0.41 0.41
126 INT159052 Transcription of Fgf1 1 0.62 0.71 0.41
127 INT176085 Regulation of Tek 6 0.37 3.36 0.4
128 INT165761 Phosphorylation of Tnfsf11 3 0.75 2.76 0.4
129 INT129849 Positive_regulation of Localization of Vegfa 1 0.46 0.35 0.39
130 INT187214 Negative_regulation of Binding of Tnfsf11 1 0.25 1.01 0.38
131 INT176079 Positive_regulation of Tek 6 0.41 3.15 0.36
132 INT135188 Transcription of TNFSF11 4 0.59 0.72 0.36
133 INT133874 Negative_regulation of Gene_expression of Fgf1 2 0.24 2.82 0.36
134 INT82817 Localization of FGF1 2 0.60 2.12 0.36
135 INT254367 Transcription of TEK 1 0.14 1.08 0.36
136 INT252961 Localization of Fgf1 3 0.27 5.91 0.35
137 INT295000 Binding of Tnfsf11 5 0.32 2.27 0.32
138 INT181921 Binding of TEK 2 0.09 1.88 0.32
139 INT249533 Regulation of Localization of Src 1 0.22 0.22 0.32
140 INT254372 Negative_regulation of TEK 1 0.12 1.05 0.31
141 INT114699 Positive_regulation of Gene_expression of Fgf1 4 0.32 2.21 0.29
142 INT224619 Regulation of Positive_regulation of Vegfa 1 0.05 0.57 0.27
143 INT224638 Positive_regulation of Positive_regulation of Vegfa 1 0.06 0.57 0.27
144 INT148796 Regulation of Phosphorylation of VEGFA 3 0.35 1.66 0.26
145 INT109537 Transcription of Vegfa 2 0.44 1.32 0.26
146 INT137847 Negative_regulation of Tnfsf11 4 0.42 1.31 0.24
147 INT171374 Binding of Src 2 0.13 0.44 0.24
148 INT137608 Regulation of Localization of Vegfa 1 0.25 0.56 0.24
149 INT183120 Regulation of FGF1 3 0.10 2.53 0.23
150 INT210588 Protein_catabolism of Tnfsf11 1 0.72 1.43 0.23
151 INT332259 Positive_regulation of Positive_regulation of Fgf1 1 0.18 2.33 0.23
152 INT332258 Positive_regulation of Localization of Fgf1 1 0.18 2.32 0.23
153 INT245856 Regulation of Transcription of Fgf1 1 0.21 0.51 0.21
154 INT245863 Positive_regulation of Transcription of Fgf1 1 0.22 0.51 0.21
155 INT206159 Negative_regulation of Regulation of VEGFA 3 0.24 2.38 0.2
156 INT181788 Positive_regulation of Gene_expression of TEK 1 0.27 1.26 0.2
157 INT178481 Binding of Tek 2 0.28 1.55 0.19
158 INT176091 Regulation of Positive_regulation of Tek 1 0.37 0.22 0.18
159 INT249526 Positive_regulation of Localization of Src 1 0.24 0.1 0.16
160 INT298697 Negative_regulation of Tek 2 0.35 0.85 0.14
161 INT294997 Regulation of Gene_expression of Tnfsf11 1 0.35 0.81 0.13
162 INT205562 Positive_regulation of Localization of Fgf1 1 0.50 0.25 0.13
163 INT193777 Negative_regulation of Fgf1 6 0.13 4.26 0.12
164 INT302444 Negative_regulation of Binding of Vegfa 2 0.57 4.08 0.12
165 INT246872 Negative_regulation of Localization of Vegfa 2 0.41 2.16 0.12
166 INT106015 Negative_regulation of Regulation of Fgf1 1 0.41 0.15 0.12
167 INT260740 Negative_regulation of Localization of Vegfa 1 0.10 0.19 0.12
168 INT226281 Regulation of TEK 1 0.60 1.33 0.11
169 INT210605 Negative_regulation of Negative_regulation of TNFSF11 2 0.42 1.65 0.1
170 INT184511 Positive_regulation of Negative_regulation of VEGFA 5 0.46 2.86 0.09
171 INT205563 Regulation of Gene_expression of Fgf1 1 0.27 0.06 0.09
172 INT65031 Negative_regulation of Gene_expression of Fgf1 3 0.43 0.25 0.08
173 INT266341 Regulation of Localization of Fgf1 1 0.03 0.92 0.08
174 INT247569 Positive_regulation of Regulation of VEGFA 6 0.48 4.15 0.07
175 INT338740 Transcription of Src 1 0.43 1.24 0.07
176 INT224430 Positive_regulation of Transcription of TNFSF11 1 0.43 0.06 0.07
177 INT144491 Negative_regulation of Transcription of Tnfsf11 1 0.42 0.82 0.07
178 INT178495 Negative_regulation of Positive_regulation of Tek 1 0.14 1.05 0.06
179 INT200861 Negative_regulation of Binding of Tek 1 0.32 0.3 0.06
180 INT205607 Regulation of Fgf1 4 0.24 3.34 0.04
181 INT294427 Regulation of Gene_expression of Vegfa 2 0.44 2.4 0.04
182 INT210608 Negative_regulation of Binding of TNFSF11 2 0.25 2.31 0.04
183 INT178484 Positive_regulation of Phosphorylation of Tek 1 0.23 0.79 0.04
184 INT178486 Phosphorylation of Tek 1 0.27 0.73 0.04
185 INT232197 Positive_regulation of Phosphorylation of Tnfsf11 1 0.46 0.6 0.04
186 INT232196 Negative_regulation of Negative_regulation of Tnfsf11 1 0.39 1.5 0.04
187 INT210609 Positive_regulation of Localization of TNFSF11 1 0.41 1.12 0.04
188 INT295840 Positive_regulation of Regulation of Vegfa 1 0.12 0 0.03
189 INT210591 Positive_regulation of Negative_regulation of Tnfsf11 1 0.47 1.46 0.03
190 INT312928 Localization of Tek 1 0.31 0.66 0.03
191 INT260288 Binding of FGF1 3 0.32 2.46 0
192 INT225256 Positive_regulation of Gene_expression of Src 3 0.20 0.75 0
193 INT112325 Transcription of Vegfa 2 0.41 1.11 0
194 INT265570 Binding of Fgf1 2 0.10 0.91 0
195 INT338741 Negative_regulation of Binding of Src 1 0.30 0.75 0
196 INT143447 Regulation of Protein_catabolism of VEGFA 1 0.27 0.15 0
197 INT225249 Negative_regulation of Phosphorylation of Src 1 0.16 1.51 0
198 INT221486 Positive_regulation of Binding of TNFSF11 1 0.15 0.98 0
199 INT312931 Negative_regulation of Regulation of Tek 1 0.19 0.23 0
200 INT274022 Regulation of Positive_regulation of TNFSF11 1 0.05 0.29 0
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