GO:0010800

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Name positive regulation of peptidyl-threonine phosphorylation
Categary Process
Go Slim No
Go Link GO:0010800
Unique Molecular Interactions 970
Total Molecular Interactions 1239
Total Single Events 9529
Pain Genes Associated 25

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of peptidyl-threonine phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of peptidyl-threonine phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
2 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
3 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
4 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
5 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
6 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
7 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
8 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
9 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
10 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
11 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
12 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
13 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
14 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41
15 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41
16 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35
17 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
18 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
19 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
20 INT220751 EGF Regulation of GOPC 1 0.08 0 1.18
21 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
22 INT220752 Negative_regulation of EGF Regulation of NAV1 1 0.26 0 1.18
23 INT220753 Negative_regulation of EGF Regulation of GOPC 1 0.08 0 1.18
24 INT220748 EGF Regulation of NAV1 1 0.28 0 1.17
25 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17
26 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
27 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
28 INT136989 EGF Negative_regulation of Positive_regulation of KCNJ2 1 0.04 1.09 1.1
29 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
30 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04
31 INT136988 EGF Negative_regulation of KCNJ2 1 0.04 1.09 1.04
32 INT338894 TNFSF14 Negative_regulation of Gsk3a 1 0.00 0.54 1.04
33 INT101443 Penk Positive_regulation of Localization of Gcg 1 0.50 1.21 1.04
34 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03
35 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
36 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
37 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
38 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94
39 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93
40 INT223871 Ltp Positive_regulation of Gene_expression of Mapk1 1 0.33 0 0.93
41 INT72386 Egf Positive_regulation of Phosphorylation of Shc1 1 0.09 0.18 0.93
42 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91
43 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91
44 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
45 INT220744 EGF Positive_regulation of Gene_expression of KRT20 1 0.01 1.26 0.9
46 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
47 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
48 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
49 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
50 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
51 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
52 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
53 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
54 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85
55 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
56 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
57 INT220739 EGF Positive_regulation of Transcription of NAV1 1 0.31 0.16 0.83
58 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
59 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
60 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
61 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81
62 INT84039 EGF Positive_regulation of Gene_expression of CPOX 2 0.11 1.88 0.8
63 INT84040 EGF Positive_regulation of CPOX 2 0.07 1.91 0.8
64 INT220747 Binding of PCa and EGF 1 0.05 1.42 0.8
65 INT42797 Egf Regulation of Gene_expression of Penk 1 0.21 0.07 0.8
66 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8
67 INT161520 H2-M3 Regulation of Positive_regulation of Mapk1 1 0.09 0.47 0.79
68 INT132977 Tac1 Positive_regulation of Mapk1 1 0.06 0.17 0.79
69 INT117909 Mastl Positive_regulation of Mapk1 1 0.04 0 0.79
70 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
71 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
72 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
73 INT231031 Egf Positive_regulation of Sec22b 1 0.03 0.05 0.76
74 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
75 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
76 INT31642 POMC Regulation of GCG 1 0.41 0.62 0.73
77 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
78 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
79 INT101676 Sst Negative_regulation of Localization of Gcg 1 0.03 0 0.72
80 INT220746 EGF Positive_regulation of Gene_expression of GOPC 1 0.13 0 0.72
81 INT101444 Penk Regulation of Localization of Gcg 1 0.45 0.77 0.71
82 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 1 0.46 0.25 0.7
83 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
84 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7
85 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 0.03 1.21 0.7
86 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
87 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
88 INT223876 Mapk1 Positive_regulation of Atf6b 1 0.10 0 0.68
89 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
90 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67
91 INT211916 Fig4 Positive_regulation of Mapk1 1 0.13 0.25 0.66
92 INT191332 AMPH Positive_regulation of Mapk1 1 0.76 0 0.66
93 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
94 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 0.03 0 0.65
95 INT31418 Positive_regulation of Adra2c Positive_regulation of Gcg 1 0.22 0 0.65
96 INT148173 Positive_regulation of Grm5 Positive_regulation of Phosphorylation of Mapk1 1 0.01 0.45 0.65
97 INT281092 Adcy1 Positive_regulation of Mapk1 1 0.21 0 0.63
98 INT281090 Prkacb Positive_regulation of Mapk1 1 0.06 0 0.62
99 INT30902 GCG Positive_regulation of Localization of SST 1 0.11 0.05 0.62
100 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
101 INT169287 EGF Positive_regulation of Localization of IL8 1 0.15 0.13 0.61
102 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
103 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
104 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
105 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
106 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
107 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
108 INT148172 Mapk1 Positive_regulation of Phosphorylation of Kcnd2 1 0.49 0.55 0.57
109 INT199976 EGF Regulation of ITGB3BP 1 0.02 0.77 0.57
110 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
111 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
112 INT201949 CXCL10 Positive_regulation of Phosphorylation of MAPK1 1 0.15 0.79 0.55
113 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
114 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
115 INT121993 Binding of EGF and SGCG 1 0.40 0 0.55
116 INT176340 CHI3L1 Positive_regulation of Localization of CSF2 1 0.11 1.86 0.55
117 INT176343 CHI3L1 Positive_regulation of Localization of CSF1 1 0.23 1.86 0.55
118 INT323146 PRKCA Positive_regulation of MAPK1 1 0.02 0 0.54
119 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
120 INT85125 IL3 Positive_regulation of MAPK1 1 0.30 0.81 0.53
121 INT85121 CSF2 Positive_regulation of MAPK1 1 0.07 0.8 0.53
122 INT85115 IL5 Positive_regulation of MAPK1 1 0.14 0.81 0.53
123 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52
124 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
125 INT171910 MAPK1 Positive_regulation of MAPK9 1 0.10 1.55 0.52
126 INT201939 CXCL10 Positive_regulation of MAPK1 1 0.11 0.72 0.52
127 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
128 INT220745 EGF Positive_regulation of Positive_regulation of PCa 1 0.05 0.79 0.52
129 INT171914 MAPK8IP3 Positive_regulation of Gene_expression of MAPK1 1 0.06 1.55 0.52
130 INT122872 SEMA6A Positive_regulation of MAPK1 1 0.56 0 0.52
131 INT108467 GCG Positive_regulation of Cck 1 0.02 0.16 0.51
132 INT131368 MAPK1 Positive_regulation of Bcar3 1 0.00 0.37 0.51
133 INT7849 Man2a2 Positive_regulation of Localization of Gcg 1 0.08 0 0.51
134 INT131369 MAPK1 Positive_regulation of Il4 1 0.01 0.37 0.51
135 INT356286 Ngf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
136 INT356279 Gdnf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
137 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
138 INT194676 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.34 0.5
139 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
140 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
141 INT98734 Egf Negative_regulation of Tk1 1 0.13 0.15 0.49
142 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
143 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
144 INT295708 Binding of EGF and CCL2 1 0.01 0.79 0.49
145 INT108329 EGF Positive_regulation of Phosphorylation of EPHB2 4 0.48 3.96 0.48
146 INT25524 Oprd1 Regulation of Localization of GCG 1 0.01 0.52 0.48
147 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.49 0.48
148 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
149 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
150 INT102555 HGF Positive_regulation of MAPK1 1 0.38 0.47 0.47
151 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46
152 INT254198 Mapk1 Positive_regulation of Mapk8 1 0.01 0.87 0.46
153 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
154 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46
155 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
156 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46
157 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45
158 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
159 INT190870 BDNF Positive_regulation of Phosphorylation of Mapk1 1 0.12 0.54 0.44
160 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44
161 INT223863 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Ltp 1 0.31 0 0.43
162 INT295406 Egf Regulation of Gene_expression of Oprk1 1 0.01 0.72 0.43
163 INT264473 Il1a Positive_regulation of Mapk1 1 0.00 0 0.43
164 INT311590 EGF Regulation of Gene_expression of CXCL10 1 0.23 0.51 0.43
165 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43
166 INT265647 Binding of Ephb1 and Mapk1 1 0.00 1.48 0.43
167 INT264471 Il1a Positive_regulation of Gene_expression of Mapk1 1 0.01 0 0.43
168 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
169 INT311591 CXCL10 Regulation of Gene_expression of EGF 1 0.23 0.51 0.43
170 INT254347 FASLG Negative_regulation of Gene_expression of CHI3L1 1 0.13 0.92 0.42
171 INT13281 Egf Regulation of Ngf 1 0.66 0.12 0.42
172 INT238913 MAPK3 Regulation of Positive_regulation of MAPK1 1 0.11 0.39 0.42
173 INT161521 Negative_regulation of H2-M3 Positive_regulation of Mapk1 1 0.14 0.41 0.42
174 INT13279 Ngf Regulation of Egf 1 0.49 0.12 0.42
175 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41
176 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
177 INT274864 Negative_regulation of Mapk1 Negative_regulation of Gene_expression of TNF 1 0.05 1.15 0.41
178 INT161522 H2-M3 Positive_regulation of Mapk1 1 0.15 0.41 0.41
179 INT274867 Negative_regulation of Mapk1 Negative_regulation of TNF 1 0.03 1.15 0.41
180 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
181 INT13283 Egf Regulation of Fgf2 1 0.49 0.11 0.41
182 INT13284 Fgf2 Regulation of Egf 1 0.49 0.11 0.41
183 INT124260 Plat Positive_regulation of Mapk1 1 0.14 0.81 0.41
184 INT194705 Negative_regulation of MAPK1 Negative_regulation of Positive_regulation of IK 1 0.00 1.46 0.41
185 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
186 INT113474 MAPK1 Negative_regulation of TNF 1 0.13 0.23 0.4
187 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
188 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
189 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
190 INT90807 EGF Positive_regulation of Oprd1 1 0.00 0.39 0.39
191 INT183924 Binding of CHI3L1 and HLA-E 1 0.08 0.9 0.39
192 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
193 INT152239 Mapk1 Positive_regulation of Localization of Nfkb1 1 0.29 0.13 0.39
194 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
195 INT283840 Binding of Egf and hb 1 0.21 1.34 0.38
196 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38
197 INT194713 MAPK1 Regulation of Gene_expression of TNF 1 0.10 1.66 0.38
198 INT43956 GCG Regulation of ALB 1 0.16 0.15 0.38
199 INT207643 Prkca Positive_regulation of Mapk1 1 0.09 0.17 0.37
200 INT304501 Binding of Ephb1 and Mapk1 1 0.18 0.69 0.36

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of peptidyl-threonine phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of peptidyl-threonine phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
2 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
3 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
4 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
5 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
6 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
7 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
8 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
9 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
10 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
11 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
12 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
13 INT1473 Localization of Gcg 95 0.80 17.35 30.31
14 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47
15 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
16 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
17 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
18 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
19 INT17625 Localization of GCG 210 0.80 55.69 24.97
20 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
21 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
22 INT11157 Binding of EGF 88 0.48 53.73 21.25
23 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
24 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
25 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31
26 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59
27 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
28 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
29 INT128401 Positive_regulation of Positive_regulation of Mapk1 39 0.70 10.88 15.38
30 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
31 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
32 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
33 INT91544 Gene_expression of CHI3L1 60 0.75 77.72 13.9
34 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68
35 INT6575 Positive_regulation of Localization of Gcg 33 0.69 3.48 13.31
36 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99
37 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37
38 INT119396 Regulation of Positive_regulation of Mapk1 22 0.61 7.88 12.25
39 INT2586 Positive_regulation of Gcg 35 0.70 9.25 11.75
40 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
41 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
42 INT48921 Regulation of Mapk1 25 0.49 19.51 10.41
43 INT8740 Localization of Gcg 65 0.78 19 9.81
44 INT2036 Localization of EGF 42 0.77 21.5 9.74
45 INT4494 Regulation of GCG 41 0.45 18.38 9.68
46 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48
47 INT24328 Gene_expression of Egf 97 0.75 59.65 9.42
48 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
49 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
50 INT109432 Negative_regulation of Phosphorylation of Mapk1 19 0.54 7.01 8.98
51 INT22771 Positive_regulation of Egf 44 0.70 16.45 8.64
52 INT3658 Regulation of Gcg 28 0.53 12.89 8.58
53 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35
54 INT126848 Positive_regulation of Phosphorylation of Mapk1 30 0.50 15.94 8.34
55 INT2587 Regulation of Localization of Gcg 22 0.60 1.73 7.59
56 INT3659 Negative_regulation of Gcg 26 0.51 10.08 7.39
57 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
58 INT2037 Negative_regulation of EGF 30 0.59 15.05 6.81
59 INT48928 Positive_regulation of Gene_expression of Mapk1 19 0.48 9.38 6.59
60 INT13822 Localization of Egf 30 0.81 13.79 6.4
61 INT116641 Phosphorylation of Gsk3a 12 0.71 4.3 6.22
62 INT15528 Positive_regulation of GCG 38 0.63 20.47 6.14
63 INT139964 Regulation of Phosphorylation of Mapk1 12 0.58 10.04 6.1
64 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9
65 INT3894 Negative_regulation of Localization of Gcg 18 0.52 2.7 5.77
66 INT31227 Regulation of Localization of GCG 28 0.48 4.86 5.72
67 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
68 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
69 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39
70 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
71 INT37227 Regulation of EGF 19 0.45 11.16 5.17
72 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
73 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
74 INT21901 Negative_regulation of Egf 25 0.58 10.46 4.99
75 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98
76 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75
77 INT128746 Negative_regulation of Gsk3a 11 0.52 8.43 4.61
78 INT8743 Positive_regulation of Gcg 19 0.65 10.63 4.43
79 INT125884 Positive_regulation of CHI3L1 15 0.62 34.04 4.43
80 INT1634 Gene_expression of Gcg 25 0.75 14.98 4.42
81 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
82 INT8744 Regulation of Localization of Gcg 14 0.60 2.06 4.3
83 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
84 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21
85 INT65926 Positive_regulation of Gene_expression of Egf 26 0.70 12.91 4.18
86 INT158416 Localization of Mapk1 19 0.67 5.32 4.18
87 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
88 INT23653 Binding of Egf 22 0.36 11.34 4.12
89 INT17626 Positive_regulation of Localization of GCG 36 0.69 13.94 4.06
90 INT133244 Regulation of Positive_regulation of Mapk1 11 0.43 3.52 4.03
91 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
92 INT113924 Binding of Mapk1 27 0.38 8.64 3.84
93 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
94 INT31758 Positive_regulation of Egf 32 0.66 19.42 3.64
95 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
96 INT18920 Binding of Egf 24 0.48 9.43 3.57
97 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53
98 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
99 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
100 INT8096 Positive_regulation of Gene_expression of EGF 21 0.69 13.43 3.47
101 INT8748 Positive_regulation of Localization of Gcg 24 0.67 9.74 3.46
102 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
103 INT31414 Gene_expression of Gcg 25 0.73 7.28 3.25
104 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
105 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
106 INT171368 Regulation of Phosphorylation of Mapk1 14 0.61 4.77 3.14
107 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
108 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
109 INT31757 Negative_regulation of Egf 18 0.41 9.7 2.94
110 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
111 INT117785 Regulation of Gene_expression of EGF 7 0.44 4.22 2.87
112 INT200895 Localization of Mapk1 6 0.67 2.08 2.82
113 INT169112 Negative_regulation of Positive_regulation of Mapk1 9 0.59 1.84 2.78
114 INT145821 Negative_regulation of Gene_expression of Mapk1 16 0.41 8.05 2.77
115 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
116 INT152927 Negative_regulation of Mapk1 16 0.41 5.85 2.73
117 INT125885 Positive_regulation of Gene_expression of CHI3L1 8 0.49 10.8 2.64
118 INT28878 Negative_regulation of Localization of Egf 6 0.49 10.34 2.57
119 INT77636 Phosphorylation of Egf 11 0.61 1.69 2.56
120 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
121 INT92000 Gene_expression of Gsk3a 12 0.18 4.12 2.39
122 INT186116 Regulation of Gene_expression of MAPK1 9 0.44 5.85 2.32
123 INT121589 Negative_regulation of GSK3A 10 0.53 9.11 2.22
124 INT43282 Binding of Gcg 5 0.32 0.61 2.18
125 INT56705 Negative_regulation of Positive_regulation of Gcg 1 0.51 0 2.17
126 INT15983 Regulation of Gcg 6 0.58 1.67 2.16
127 INT82226 Negative_regulation of Gene_expression of EGF 11 0.58 6.36 2.13
128 INT170482 Regulation of Gene_expression of Mapk1 5 0.43 5.73 2.1
129 INT108335 Phosphorylation of EGF 17 0.80 7.3 2.09
130 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
131 INT109906 Localization of MAPK1 12 0.54 1.68 2.01
132 INT83709 Negative_regulation of Gene_expression of MAPK1 12 0.41 6.57 2.01
133 INT158022 Binding of CHI3L1 10 0.43 14.18 1.94
134 INT8745 Negative_regulation of Gcg 13 0.40 4.84 1.91
135 INT204018 Localization of Gsk3b 27 0.71 13.67 1.87
136 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
137 INT172961 Localization of Egf 26 0.71 16.74 1.81
138 INT73721 Negative_regulation of Gene_expression of Egf 5 0.43 2.28 1.8
139 INT90800 Negative_regulation of Positive_regulation of EGF 5 0.40 2.78 1.77
140 INT19747 Regulation of Egf 14 0.46 4.67 1.68
141 INT28954 Binding of GCG 7 0.36 3.14 1.68
142 INT26180 Regulation of Regulation of GCG 3 0.39 1.43 1.65
143 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
144 INT248321 Regulation of Gene_expression of CHI3L1 2 0.44 10.73 1.64
145 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
146 INT169461 Regulation of Gene_expression of Mapk1 7 0.44 1.64 1.61
147 INT261849 Positive_regulation of Phosphorylation of Gsk3a 3 0.14 1.15 1.57
148 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
149 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
150 INT98773 Negative_regulation of Localization of Gcg 10 0.53 9.59 1.5
151 INT130019 Regulation of Phosphorylation of MAPK1 6 0.49 3.6 1.5
152 INT114525 Negative_regulation of Positive_regulation of Egf 4 0.35 2.93 1.5
153 INT86382 Negative_regulation of Localization of EGF 5 0.43 1.75 1.44
154 INT190646 Regulation of Regulation of Mapk1 1 0.30 1.16 1.43
155 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
156 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
157 INT153627 Binding of Mapk1 5 0.36 2.88 1.4
158 INT124212 Protein_catabolism of CHI3L1 3 0.21 3.48 1.4
159 INT104027 Negative_regulation of Negative_regulation of MAPK1 6 0.56 2.87 1.35
160 INT163506 Binding of Gsk3a 4 0.32 1.41 1.31
161 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
162 INT145312 Localization of CHI3L1 8 0.78 12.71 1.26
163 INT27108 Positive_regulation of Localization of Egf 5 0.50 2.91 1.21
164 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
165 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16
166 INT58311 Regulation of Localization of EGF 3 0.54 1.06 1.16
167 INT208974 Negative_regulation of Chi3l1 1 0.01 0.12 1.16
168 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15
169 INT65734 Regulation of Chi3l1 2 0.06 1.25 1.15
170 INT162124 Positive_regulation of Phosphorylation of Egf 3 0.45 0.77 1.14
171 INT22770 Regulation of Gene_expression of Egf 5 0.44 2.56 1.12
172 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11
173 INT208536 Positive_regulation of Positive_regulation of Gsk3b 6 0.30 4.83 1.11
174 INT37207 Positive_regulation of Positive_regulation of Egf 4 0.50 0.76 1.07
175 INT13817 Protein_catabolism of EGF 3 1.00 1.44 1.06
176 INT105860 Positive_regulation of Positive_regulation of EGF 6 0.64 2.37 1.05
177 INT10264 Regulation of Regulation of Gcg 2 0.39 0 1.05
178 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
179 INT116646 Regulation of Negative_regulation of Gsk3b 2 0.44 0.39 0.99
180 INT184240 Positive_regulation of Localization of Egf 2 0.27 3.58 0.99
181 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
182 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
183 INT253940 Gene_expression of Gsk3a 1 0.08 2.82 0.92
184 INT261360 Binding of Gsk3b 5 0.36 2.85 0.9
185 INT253938 Positive_regulation of Gsk3a 3 0.06 3.4 0.9
186 INT118290 Regulation of Phosphorylation of EGF 1 0.32 0.72 0.87
187 INT91995 Positive_regulation of Gsk3a 8 0.14 2.84 0.86
188 INT102988 Regulation of CHI3L1 5 0.48 7.23 0.86
189 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
190 INT124210 Negative_regulation of CHI3L1 7 0.12 4.39 0.85
191 INT171372 Positive_regulation of Gene_expression of Egf 16 0.66 9.82 0.84
192 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
193 INT307469 Regulation of Gsk3a 4 0.09 1.12 0.83
194 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
195 INT167285 Positive_regulation of Phosphorylation of Gsk3b 17 0.50 5.92 0.82
196 INT156945 Positive_regulation of Negative_regulation of Gsk3b 6 0.38 4.58 0.82
197 INT182180 Transcription of CHI3L1 1 0.67 1.94 0.82
198 INT66365 Positive_regulation of Gene_expression of Gsk3b 2 0.07 0.95 0.81
199 INT179441 Gene_expression of Chi3l1 1 0.02 0 0.81
200 INT139323 Positive_regulation of Negative_regulation of Tgfb1 1 0.45 0 0.79
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