GO:0010801

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Name negative regulation of peptidyl-threonine phosphorylation
Categary Process
Go Slim No
Go Link GO:0010801
Unique Molecular Interactions 41
Total Molecular Interactions 47
Total Single Events 284
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of peptidyl-threonine phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of peptidyl-threonine phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
2 INT299113 Binding of INPP5K and GOPC 1 0.18 2.69 0.19
3 INT67619 Inpp5k Negative_regulation of Ptgs1 1 0.03 0.5 0.13
4 INT312218 INPP5K Positive_regulation of Protein_catabolism of IGFBP3 1 0.17 0.39 0.11
5 INT312212 Binding of ADAM12 and INPP5K 1 0.16 0.46 0.11
6 INT228808 Smad7 Regulation of Rgs1 1 0.19 0.24 0.09
7 INT228812 Smad7 Regulation of Stap1 1 0.00 0.24 0.09
8 INT134837 TGFB1 Regulation of SMAD7 1 0.34 0.68 0.08
9 INT134833 TGFB1 Regulation of Gene_expression of SMAD7 1 0.34 0.69 0.08
10 INT134838 TGFB1 Positive_regulation of SMAD7 1 0.52 0.79 0.08
11 INT312228 INPP5K Regulation of TGFB1 1 0.06 0.08 0.05
12 INT312226 INPP5K Positive_regulation of IGFBP5 1 0.12 0.07 0.05
13 INT332411 Akt1 Positive_regulation of Phosphorylation of Met 1 0.31 0.05 0.04
14 INT332410 Mapk1 Positive_regulation of Phosphorylation of Met 1 0.32 0.05 0.04
15 INT310041 Gtf3a Positive_regulation of Met 1 0.00 0.15 0.03
16 INT353287 Prdx2 Positive_regulation of Phosphorylation of Smad7 1 0.22 0.06 0.03
17 INT353291 Prdx2 Positive_regulation of Smad7 1 0.31 0.06 0.03
18 INT310040 Hgf Positive_regulation of Met 1 0.06 0.15 0.03
19 INT353288 Smad7 Negative_regulation of Phosphorylation of Tgif1 1 0.08 0.06 0.03
20 INT120077 Gene_expression of Smad7 Negative_regulation of Positive_regulation of Itk 1 0.02 0.27 0
21 INT312224 INPP5K Regulation of Negative_regulation of COL1A1 1 0.08 0 0
22 INT312221 Binding of TGFB1 and INPP5K 1 0.09 0 0
23 INT312220 IL4 Positive_regulation of Regulation of INPP5K 1 0.05 0.24 0
24 INT312222 IFNA1 Positive_regulation of Regulation of INPP5K 1 0.05 0.24 0
25 INT218663 Olr811 Positive_regulation of Gene_expression of Smad7 1 0.01 0.45 0
26 INT310043 Binding of Met and Slc30a4 1 0.05 0.35 0
27 INT134836 Binding of SMAD7 and YAP1 1 0.53 0.89 0
28 INT312230 INPP5K Regulation of Gene_expression of COL2A1 1 0.06 0 0
29 INT312225 Positive_regulation of INPP5K Positive_regulation of CD44 1 0.15 0.1 0
30 INT312214 INPP5K Regulation of Gene_expression of COL1A1 1 0.08 0 0
31 INT310188 Binding of Adcyap1r1 and Smad7 1 0.00 0 0
32 INT347155 Mirlet7a-1 Negative_regulation of Smad7 1 0.10 0 0
33 INT312223 INPP5K Negative_regulation of Gene_expression of COL10A1 1 0.04 0.1 0
34 INT332405 Met Regulation of Positive_regulation of Mapk1 1 0.17 0.18 0
35 INT312227 INPP5K Regulation of Negative_regulation of COL2A1 1 0.06 0 0
36 INT312215 INPP5K Negative_regulation of COL10A1 1 0.03 0.1 0
37 INT312229 INPP5K Positive_regulation of CD44 1 0.15 0.1 0
38 INT312216 INPP5K Negative_regulation of Gene_expression of RUNX2 1 0.15 0.1 0
39 INT312213 INPP5K Regulation of COL2A1 1 0.06 0 0
40 INT312217 Binding of INS and INPP5K 1 0.03 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of peptidyl-threonine phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of peptidyl-threonine phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69
2 INT15157 Gene_expression of INPP5K 30 0.67 15.49 2.85
3 INT67618 Positive_regulation of Inpp5k 3 0.45 0.77 2.64
4 INT174924 Gene_expression of Smad7 6 0.41 3.59 1.76
5 INT174923 Positive_regulation of Gene_expression of Smad7 3 0.37 2.3 1.73
6 INT141455 Negative_regulation of Inpp5k 2 0.36 1.09 1.51
7 INT125296 Regulation of Inpp5k 1 0.22 0 1.32
8 INT120076 Positive_regulation of Gene_expression of Smad7 16 0.65 11.33 1.25
9 INT143846 Positive_regulation of INPP5K 5 0.40 6.4 1.17
10 INT272878 Negative_regulation of Smad7 4 0.41 3.86 0.72
11 INT131421 Localization of INPP5K 9 0.74 4.3 0.59
12 INT299115 Regulation of INPP5K 6 0.39 4.11 0.59
13 INT228243 Negative_regulation of Met 3 0.41 4.78 0.51
14 INT120074 Regulation of Gene_expression of Smad7 1 0.58 2.05 0.5
15 INT224538 Negative_regulation of Gene_expression of Smad7 1 0.09 0.25 0.43
16 INT132881 Binding of INPP5K 7 0.48 4.35 0.33
17 INT119907 Binding of Inpp5k 3 0.33 0.6 0.32
18 INT134840 Gene_expression of SMAD7 1 0.74 2.74 0.31
19 INT184716 Binding of Smad7 2 0.34 0.91 0.29
20 INT272890 Regulation of Negative_regulation of Smad7 1 0.19 1.33 0.29
21 INT193847 Gene_expression of Met 22 0.65 6.6 0.24
22 INT173164 Negative_regulation of INPP5K 4 0.51 2.01 0.24
23 INT228793 Negative_regulation of Gene_expression of Smad7 5 0.25 2.33 0.23
24 INT332367 Regulation of Met 1 0.58 0.7 0.2
25 INT310012 Positive_regulation of Met 9 0.65 3.57 0.19
26 INT228790 Positive_regulation of Smad7 4 0.41 0.58 0.15
27 INT226831 Regulation of Gene_expression of Met 2 0.37 0.44 0.15
28 INT332353 Phosphorylation of Met 1 0.77 0.5 0.1
29 INT353267 Negative_regulation of Positive_regulation of Smad7 1 0.25 0.32 0.08
30 INT299116 Regulation of Gene_expression of INPP5K 1 0.39 1.13 0.06
31 INT322923 Positive_regulation of Positive_regulation of INPP5K 1 0.39 1.51 0.06
32 INT347149 Localization of Smad7 1 0.67 0 0.05
33 INT226827 Binding of Met 3 0.10 1.24 0.04
34 INT310005 Positive_regulation of Positive_regulation of Met 1 0.14 0.62 0.04
35 INT332371 Positive_regulation of Phosphorylation of Met 1 0.47 0.05 0.04
36 INT332376 Negative_regulation of Positive_regulation of Met 1 0.55 0 0.04
37 INT310008 Negative_regulation of Gene_expression of Met 2 0.41 0.48 0.03
38 INT285357 Positive_regulation of Gene_expression of Inpp5k 1 0.16 0.17 0.03
39 INT285359 Gene_expression of Inpp5k 1 0.22 0.17 0.03
40 INT350515 Transcription of SMAD7 1 0.07 0.38 0.03
41 INT353280 Phosphorylation of Smad7 1 0.48 0.06 0.03
42 INT332366 Positive_regulation of Negative_regulation of Met 1 0.44 0.24 0
43 INT310009 Localization of Met 1 0.20 0.22 0
44 INT310017 Regulation of Negative_regulation of Met 1 0.43 0.68 0
45 INT347148 Regulation of Smad7 1 0.26 0 0
46 INT218701 Negative_regulation of Binding of Smad7 1 0.14 0.15 0
47 INT166121 Binding of SMAD7 1 0.30 0.39 0
48 INT193874 Positive_regulation of Gene_expression of Met 1 0.49 0.48 0
49 INT353273 Negative_regulation of Phosphorylation of Smad7 1 0.25 0 0
50 INT226830 Transcription of Met 1 0.06 0.05 0
51 INT347145 Transcription of Smad7 1 0.68 0 0
52 INT218685 Binding of Smad7 1 0.13 0.15 0
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