GO:0010811

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Name positive regulation of cell-substrate adhesion
Categary Process
Go Slim No
Go Link GO:0010811
Unique Molecular Interactions 288
Total Molecular Interactions 382
Total Single Events 2132
Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cell-substrate adhesion. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of cell-substrate adhesion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
2 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
3 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
4 INT24817 Binding of POMC and VTN 8 0.42 0.39 1.71
5 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
6 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
7 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
8 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
9 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
10 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
11 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
12 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
13 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
14 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
15 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
16 INT136795 Spp1 Positive_regulation of Chuk 1 0.11 1.54 0.77
17 INT113549 Binding of VTN and alphavbeta3 integrin receptor 1 0.09 2.05 0.76
18 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
19 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
20 INT148454 Gene_expression of Inhbe Positive_regulation of Prkce 1 0.08 0.67 0.69
21 INT185802 Binding of MMP7 and SPP1 1 0.33 1.71 0.68
22 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
23 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
24 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64
25 INT185809 Binding of PDX1 and SPP1 1 0.02 1.69 0.57
26 INT227911 Binding of VTN and MMRN1 1 0.01 1.16 0.56
27 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
28 INT150791 THBS1 Negative_regulation of TIMP2 1 0.17 0.5 0.52
29 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
30 INT150796 ZNF398 Positive_regulation of THBS1 1 0.06 0.5 0.52
31 INT150785 THBS1 Negative_regulation of MMP2 1 0.10 0.5 0.52
32 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
33 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
34 INT185800 SPP1 Negative_regulation of Gene_expression of MMP1 1 0.26 1.03 0.49
35 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
36 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
37 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
38 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
39 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
40 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
41 INT106001 Binding of PLAUR and VTN 2 0.23 1.5 0.45
42 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
43 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39
44 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
45 INT185811 SPP1 Positive_regulation of MMP3 1 0.14 0.83 0.38
46 INT185814 Binding of MMP3 and SPP1 1 0.15 0.83 0.38
47 INT113551 Binding of ITGA3 and VTN 1 0.02 1.03 0.38
48 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
49 INT130930 Egr1 Negative_regulation of Positive_regulation of Thbs1 1 0.58 0.64 0.38
50 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
51 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38
52 INT303994 Il6 Positive_regulation of JAK2 1 0.03 0.41 0.37
53 INT185804 MMP2 Positive_regulation of SPP1 1 0.15 0.88 0.37
54 INT113555 Negative_regulation of Binding of FN1 and VTN 1 0.23 0.87 0.37
55 INT185795 MMP7 Positive_regulation of SPP1 1 0.38 0.81 0.37
56 INT113559 Binding of PLAU and VTN 1 0.28 0.82 0.37
57 INT113554 Negative_regulation of Binding of PLAU and VTN 1 0.32 0.87 0.37
58 INT113547 Negative_regulation of Binding of PLAUR and VTN 1 0.26 0.87 0.37
59 INT185798 SPP1 Positive_regulation of Gene_expression of MMP2 1 0.26 0.87 0.37
60 INT185807 SPP1 Positive_regulation of MMP7 1 0.56 0.79 0.36
61 INT133307 Binding of CD44 and SPP1 5 0.26 2.6 0.35
62 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
63 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
64 INT242995 Agt Positive_regulation of Spp1 1 0.36 1.82 0.33
65 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
66 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
67 INT282420 Spp1 Positive_regulation of Ins1 1 0.20 1.25 0.32
68 INT127974 RAX2 Positive_regulation of SPP1 1 0.03 1.49 0.31
69 INT140386 Spp1 Positive_regulation of NFKB1 1 0.21 1.29 0.3
70 INT251388 Binding of Fbln2 and Gabbr1 1 0.08 0.07 0.3
71 INT140385 Spp1 Negative_regulation of FOXO3 1 0.04 1.29 0.3
72 INT179844 Nid1 Regulation of Negative_regulation of Il11 1 0.19 0 0.29
73 INT185799 Binding of EGFR and SPP1 1 0.19 0.64 0.29
74 INT185813 Binding of MMP7 and Positive_regulation of SPP1 1 0.46 0.85 0.28
75 INT185818 SPP1 Positive_regulation of Gene_expression of COL7A1 1 0.10 0.82 0.28
76 INT344402 Binding of Crp and Spp1 1 0.05 2.92 0.28
77 INT203733 Thbs1 Positive_regulation of Negative_regulation of Ppara 1 0.36 1.55 0.26
78 INT242991 Agt Positive_regulation of Gene_expression of Spp1 1 0.21 0.66 0.26
79 INT252356 Binding of THBS1 and Cd47 1 0.00 0.44 0.24
80 INT136798 Spp1 Regulation of Gene_expression of PTGS2 1 0.08 0.65 0.24
81 INT329311 Spp1 Positive_regulation of IFN1@ 1 0.20 1.2 0.23
82 INT329306 Spp1 Positive_regulation of Il12a 1 0.08 1.19 0.23
83 INT299155 Smcp Negative_regulation of Spp1 1 0.00 0.7 0.22
84 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21
85 INT242994 Adipoq Negative_regulation of Spp1 1 0.19 0.59 0.21
86 INT240536 Il12a Positive_regulation of Jak2 1 0.10 0.74 0.21
87 INT51345 Binding of Vtn and Pomc 1 0.03 0 0.2
88 INT329310 Spp1 Positive_regulation of Gene_expression of IFN1@ 1 0.48 0.88 0.19
89 INT336892 Positive_regulation of Epc2 Positive_regulation of Localization of Spp1 1 0.00 0.62 0.19
90 INT336890 Positive_regulation of Epc2 Positive_regulation of Spp1 1 0.00 0.62 0.19
91 INT185805 SPP1 Regulation of MMP7 1 0.25 0.38 0.19
92 INT329309 Spp1 Regulation of Gene_expression of IFN1@ 1 0.26 0.82 0.19
93 INT185816 SPP1 Positive_regulation of Positive_regulation of MMP7 1 0.46 0.36 0.18
94 INT337260 ELL Positive_regulation of Gene_expression of THBS1 1 0.11 0.82 0.18
95 INT242993 Positive_regulation of Ppara Positive_regulation of Gene_expression of Spp1 1 0.24 0.66 0.18
96 INT337263 ELL Regulation of Gene_expression of THBS1 1 0.10 0.82 0.18
97 INT185803 Binding of MMP11 and SPP1 1 0.06 0.34 0.17
98 INT185815 Binding of MMP1 and SPP1 1 0.21 0.34 0.17
99 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
100 INT185810 Binding of MMP2 and SPP1 1 0.14 0.34 0.17
101 INT329305 Spp1 Positive_regulation of Gene_expression of Il12a 1 0.12 0.88 0.16
102 INT158613 Binding of Serpine1 and Vtn 1 0.02 0.95 0.16
103 INT185808 SPP1 Positive_regulation of TIMP1 1 0.64 0.33 0.16
104 INT231677 Binding of CD47 and THBS1 1 0.18 0 0.16
105 INT147229 Positive_regulation of Ccdc80 Negative_regulation of Faah 1 0.02 0.06 0.16
106 INT185793 SPP1 Positive_regulation of COL1A2 1 0.16 0.33 0.16
107 INT147230 Ccdc80 Negative_regulation of Faah 1 0.02 0.06 0.16
108 INT106009 Binding of VTN and Plaur 1 0.05 1.37 0.15
109 INT252352 Binding of THBS1 and Sirpa 1 0.00 0.26 0.15
110 INT58187 ITGA1 Positive_regulation of Itga3 1 0.01 1.47 0.14
111 INT327879 Binding of Itgb1 and Postn 1 0.02 1.05 0.14
112 INT300512 Binding of Plau and Vtn 1 0.06 2.28 0.13
113 INT134614 Prkce Regulation of Trpv1 1 0.30 0.15 0.13
114 INT300511 Binding of Plaur and Vtn 1 0.10 2.28 0.13
115 INT327877 Itgb1 Negative_regulation of Gene_expression of Dlk1 1 0.02 0.99 0.13
116 INT300513 Binding of Serpine1 and Vtn 1 0.17 2.27 0.13
117 INT329304 Spp1 Negative_regulation of Gene_expression of Il10 1 0.06 0.93 0.13
118 INT110107 Acot1 Positive_regulation of Localization of Prkce 1 0.11 0 0.12
119 INT88937 Mmv7 Regulation of Gene_expression of SPP1 1 0.00 1.24 0.12
120 INT329303 Spp1 Positive_regulation of Localization of Il12a 1 0.12 0.92 0.12
121 INT320768 Spp1 Regulation of Protein_catabolism of Dsg1a 1 0.08 0.77 0.11
122 INT188358 Binding of Csf2 and Positive_regulation of Jak2 1 0.34 0.19 0.11
123 INT169340 Binding of UGT8 and Jak2 1 0.36 0.15 0.11
124 INT271525 ITGB1 Positive_regulation of Gopc 1 0.02 0.57 0.11
125 INT264838 Binding of Eno2 and Spp1 1 0.00 0.17 0.1
126 INT158612 Binding of Vtn and Plaur 1 0.00 0.43 0.1
127 INT191432 Binding of COX10 and EDIL3 1 0.01 1.79 0.1
128 INT51346 Binding of Vtn and Diablo 1 0.02 0 0.1
129 INT51342 Binding of Pomc and Vtn 1 0.23 0 0.1
130 INT294439 KLK4 Negative_regulation of THBS1 1 0.01 0 0.1
131 INT51344 Binding of Clu and Vtn 1 0.06 0 0.1
132 INT184537 Ccl2 Positive_regulation of Spp1 1 0.34 1.37 0.09
133 INT158614 Negative_regulation of Binding of Serpine1 and Vtn 1 0.03 0.48 0.09
134 INT184538 Positive_regulation of Ccl2 Positive_regulation of Spp1 1 0.34 1.38 0.09
135 INT88137 Ren Regulation of Gene_expression of Spp1 1 0.04 0.24 0.09
136 INT109464 Dmp1 Negative_regulation of Tyr 1 0.04 0 0.09
137 INT45359 Spp1 Positive_regulation of Positive_regulation of Prl 1 0.21 0.23 0.09
138 INT184539 Spp1 Positive_regulation of Gpbar1 1 0.03 1.37 0.09
139 INT109465 Dmp1 Positive_regulation of Insrr 1 0.00 0 0.08
140 INT213418 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of VCAM1 1 0.29 0.15 0.08
141 INT348167 Thbs1 Positive_regulation of RAC1 1 0.04 0.71 0.08
142 INT289711 Binding of F2 and Spp1 1 0.08 0.21 0.08
143 INT205158 Gene_expression of SPP1 Positive_regulation of Gene_expression of TNFSF11 1 0.11 1.08 0.08
144 INT289710 F2 Regulation of Spp1 1 0.04 0 0.08
145 INT213419 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of HGF 1 0.25 0.15 0.08
146 INT273374 Binding of JAK2 and STAT3 1 0.24 0 0.07
147 INT273368 Negative_regulation of Binding of JAK2 and STAT3 1 0.28 0 0.07
148 INT348168 Thbs1 Positive_regulation of PIK3CD 1 0.00 0.65 0.07
149 INT133306 Positive_regulation of Binding of CD44 and SPP1 1 0.16 0.83 0.07
150 INT242480 Ciapin1 Positive_regulation of Gene_expression of Jak2 1 0.27 1.05 0.07
151 INT225781 Ppi-rs Positive_regulation of Gene_expression of Spp1 1 0.03 1 0.07
152 INT273371 JAK2 Regulation of Protein_catabolism of SOCS1 1 0.01 0 0.06
153 INT200807 Jak2 Positive_regulation of Mvd 1 0.18 3.46 0.06
154 INT325769 Binding of EPOR and Positive_regulation of Phosphorylation of JAK2 1 0.66 0 0.06
155 INT273365 JAK2 Regulation of SOCS1 1 0.01 0 0.06
156 INT317416 Binding of FN1 and ITGB1 1 0.47 0.69 0.05
157 INT238117 Positive_regulation of STAT3 Positive_regulation of Gene_expression of JAK2 1 0.11 0 0.05
158 INT203732 Thbs1 Regulation of Gene_expression of Ppara 1 0.33 0.94 0.05
159 INT205154 Binding of MMP9 and SPP1 1 0.25 0.45 0.05
160 INT238116 STAT3 Positive_regulation of Gene_expression of JAK2 1 0.16 0 0.05
161 INT341535 F2RL1 Positive_regulation of Gene_expression of THBS1 1 0.28 0.75 0.04
162 INT225791 Ppi-rs Positive_regulation of Spp1 1 0.02 0.49 0.04
163 INT202927 Binding of Fbln2 and Fbn1 1 0.14 0.29 0.04
164 INT202928 Binding of Eln and Fbln2 1 0.11 0.29 0.04
165 INT200821 Binding of Jak2 and Mvd 1 0.14 0.68 0.04
166 INT200813 Jak2 Positive_regulation of Akt1 1 0.26 1.46 0.03
167 INT253578 Csnk2a2 Negative_regulation of Jak2 1 0.09 0 0.03
168 INT253573 Binding of Jak2 and Pik3r1 1 0.06 0 0.03
169 INT200816 Jak2 Positive_regulation of Binding of Mvd 1 0.19 1.51 0.03
170 INT176549 Mtv7 Positive_regulation of Spp1 1 0.26 0.86 0.03
171 INT200810 Jak2 Positive_regulation of Src 1 0.29 1.46 0.03
172 INT249597 Jak2 Positive_regulation of Phosphorylation of Stat1 1 0.20 0.13 0.03
173 INT253575 Binding of Jak2 and Pik3r2 1 0.00 0 0.03
174 INT200815 Binding of Epo and Jak2 1 0.36 0.98 0.03
175 INT176540 Pik3cd Positive_regulation of Spp1 1 0.11 1.8 0.03
176 INT200822 Akt1 Regulation of Jak2 1 0.25 1.48 0.03
177 INT272528 THBS1 Positive_regulation of TGFB2 1 0.09 0.64 0.03
178 INT176543 Binding of Cd44 and Spp1 2 0.31 0.57 0
179 INT320766 Spp1 Negative_regulation of Dsg1a 1 0.11 1.05 0
180 INT321958 Binding of Vtn and Ceacam1 1 0.02 0.27 0
181 INT176548 Gopc Regulation of Gene_expression of Spp1 1 0.12 0 0
182 INT176538 Mapk1 Positive_regulation of Gene_expression of Spp1 1 0.12 0.43 0
183 INT309836 Binding of Cd8a and Dmp1 1 0.00 0.7 0
184 INT340502 Agtr1a Negative_regulation of Phosphorylation of Jak2 1 0.12 2.32 0
185 INT205159 SPP1 Positive_regulation of Gene_expression of TNFSF11 1 0.11 0.8 0
186 INT176551 Binding of Pik3r1 and Spp1 1 0.03 0.65 0
187 INT253366 Il6 Positive_regulation of Phosphorylation of Jak2 1 0.31 0.2 0
188 INT337270 E2F1 Positive_regulation of Transcription of THBS1 1 0.67 0.19 0
189 INT337268 E2F1 Regulation of Transcription of THBS1 1 0.44 0 0
190 INT344401 Agtr2 Positive_regulation of Gene_expression of Spp1 1 0.01 3.21 0
191 INT176534 Mapk14 Positive_regulation of Spp1 1 0.14 0.42 0
192 INT337274 E2F1 Regulation of THBS1 1 0.44 0 0
193 INT176554 Ass1 Positive_regulation of Gene_expression of Spp1 1 0.01 1.26 0
194 INT99770 Thbs1 Regulation of PGR 1 0.01 0 0
195 INT337269 Binding of E2F1 and Positive_regulation of Gene_expression of THBS1 1 0.45 0.21 0
196 INT180854 Binding of FBLN2 and NID1 1 0.01 0.92 0
197 INT185796 SPP1 Regulation of Gene_expression of COL7A1 1 0.06 0 0
198 INT337262 PRB1 Negative_regulation of THBS1 1 0.18 0.61 0
199 INT200819 Epo Positive_regulation of Gene_expression of Jak2 1 0.49 0.91 0
200 INT262750 GLYR1 Positive_regulation of THBS1 1 0.01 0.99 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cell-substrate adhesion. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of cell-substrate adhesion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31
2 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35
3 INT88650 Negative_regulation of Prkce 13 0.57 11.93 11.16
4 INT91948 Positive_regulation of Prkce 16 0.64 11.36 10.32
5 INT72148 Positive_regulation of Prkce 17 0.68 5.06 9.44
6 INT122901 Positive_regulation of Spp1 67 0.67 58.03 7.49
7 INT110104 Localization of Prkce 17 0.79 3.75 6.92
8 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51
9 INT122902 Positive_regulation of Gene_expression of Spp1 54 0.70 56.3 6.33
10 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68
11 INT101497 Phosphorylation of Prkce 9 0.81 2.55 5.59
12 INT88935 Positive_regulation of SPP1 36 0.70 31.07 5.49
13 INT91946 Regulation of Prkce 6 0.44 4.13 5.46
14 INT109838 Phosphorylation of Prkce 6 0.67 5.26 4.95
15 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
16 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
17 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59
18 INT97128 Localization of SPP1 32 0.80 21.75 4.02
19 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
20 INT109840 Localization of Prkce 5 0.74 3.01 3.45
21 INT136791 Negative_regulation of Spp1 24 0.59 23.6 3.33
22 INT110100 Negative_regulation of Prkce 5 0.57 0.68 3.16
23 INT88130 Gene_expression of Spp1 13 0.74 12.96 3.07
24 INT24821 Binding of VTN 14 0.47 5.83 3
25 INT136964 Gene_expression of Dmp1 10 0.75 3.69 2.83
26 INT128184 Positive_regulation of Positive_regulation of Prkce 4 0.41 1.3 2.64
27 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
28 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45
29 INT113339 Binding of JAK2 6 0.40 5.31 2.4
30 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
31 INT176517 Negative_regulation of Gene_expression of Spp1 18 0.59 15.31 2.28
32 INT128185 Gene_expression of Prkce 4 0.69 1.39 2.23
33 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16
34 INT136941 Positive_regulation of Localization of Prkce 3 0.43 1.42 2.06
35 INT124052 Binding of Prkce 2 0.06 2.52 2.03
36 INT176510 Binding of Spp1 21 0.42 22.1 2
37 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
38 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97
39 INT130364 Positive_regulation of Thbs1 7 0.62 7.73 1.97
40 INT176516 Localization of Spp1 28 0.76 19.39 1.9
41 INT60337 Positive_regulation of THBS1 8 0.46 4.69 1.83
42 INT63029 Gene_expression of Vtn 4 0.14 2.8 1.8
43 INT168602 Negative_regulation of Itgb1 3 0.21 1.29 1.73
44 INT133311 Binding of SPP1 10 0.37 9.47 1.65
45 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6
46 INT88136 Positive_regulation of Gene_expression of Spp1 8 0.66 4.5 1.57
47 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
48 INT88934 Regulation of SPP1 9 0.54 6.94 1.47
49 INT104250 Positive_regulation of Gene_expression of SPP1 17 0.69 13.22 1.44
50 INT57973 Positive_regulation of ITGB1 5 0.67 1.23 1.44
51 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
52 INT88133 Positive_regulation of Spp1 8 0.66 10.07 1.33
53 INT91947 Negative_regulation of Negative_regulation of Prkce 1 0.42 0.69 1.3
54 INT288546 Regulation of Positive_regulation of THBS1 1 0.36 2.65 1.27
55 INT110099 Positive_regulation of Localization of Prkce 4 0.68 1.3 1.25
56 INT91949 Regulation of Positive_regulation of Prkce 1 0.44 0.72 1.24
57 INT24819 Positive_regulation of VTN 8 0.49 3.52 1.23
58 INT150805 Localization of THBS1 4 0.46 2.88 1.23
59 INT110106 Regulation of Prkce 4 0.44 0.4 1.2
60 INT116279 Binding of Dmp1 3 0.04 0 1.2
61 INT110102 Negative_regulation of Localization of Prkce 3 0.49 0.17 1.13
62 INT131238 Negative_regulation of Positive_regulation of Prkce 1 0.41 0.44 1.12
63 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12
64 INT203729 Binding of Thbs1 1 0.27 3.83 1.1
65 INT130928 Positive_regulation of Gene_expression of Thbs1 7 0.62 5.62 1.08
66 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04
67 INT99767 Regulation of THBS1 18 0.42 11.51 1.03
68 INT184547 Localization of Spp1 4 0.58 4.44 1.02
69 INT218776 Negative_regulation of Ccdc80 2 0.02 0.97 0.99
70 INT198049 Positive_regulation of JAK2 16 0.58 5.35 0.96
71 INT135111 Regulation of Gene_expression of Prkce 1 0.51 0.15 0.96
72 INT135115 Regulation of Localization of Prkce 1 0.38 0.15 0.96
73 INT102333 Positive_regulation of Dmp1 5 0.58 0 0.94
74 INT167465 Regulation of Ccdc80 1 0.01 0.87 0.94
75 INT169336 Binding of Jak2 2 0.42 1.31 0.93
76 INT242988 Positive_regulation of Transcription of Spp1 4 0.28 3.28 0.92
77 INT134040 Regulation of Jak2 3 0.41 1.07 0.92
78 INT273038 Regulation of Vtn 3 0.08 2.26 0.91
79 INT184027 Phosphorylation of Jak2 6 0.82 2.58 0.87
80 INT113672 Positive_regulation of Gene_expression of ITGB1 3 0.49 1.4 0.86
81 INT134037 Positive_regulation of Phosphorylation of Jak2 1 0.46 0.25 0.86
82 INT136944 Positive_regulation of Positive_regulation of Prkce 2 0.46 0.8 0.85
83 INT58184 Gene_expression of Itga3 9 0.38 6.58 0.81
84 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81
85 INT237408 Positive_regulation of Positive_regulation of Jak2 1 0.28 1.56 0.79
86 INT176528 Regulation of Spp1 9 0.45 9.05 0.77
87 INT130363 Localization of Thbs1 9 0.75 4.99 0.76
88 INT185838 Protein_catabolism of SPP1 1 0.65 1.68 0.74
89 INT113342 Positive_regulation of Phosphorylation of JAK2 2 0.66 2.58 0.72
90 INT109839 Positive_regulation of Phosphorylation of Prkce 1 0.18 1.27 0.71
91 INT154761 Positive_regulation of Gene_expression of Prkce 1 0.44 0.5 0.7
92 INT154762 Negative_regulation of Phosphorylation of Prkce 1 0.38 0.48 0.69
93 INT176513 Transcription of Spp1 5 0.63 4.32 0.67
94 INT51336 Binding of Vtn 3 0.12 1.5 0.66
95 INT346193 Positive_regulation of Gene_expression of VTN 1 0.25 1.54 0.63
96 INT252993 Negative_regulation of THBS1 8 0.55 6.93 0.59
97 INT88933 Regulation of Gene_expression of SPP1 7 0.45 6.05 0.59
98 INT242987 Positive_regulation of Localization of Spp1 3 0.60 7.04 0.59
99 INT117145 Negative_regulation of Gene_expression of Thbs1 11 0.43 5.67 0.57
100 INT127975 Negative_regulation of SPP1 15 0.42 11.25 0.56
101 INT152068 Regulation of Gene_expression of Prkce 1 0.05 0.74 0.56
102 INT150808 Negative_regulation of Localization of THBS1 1 0.25 0.5 0.53
103 INT63028 Positive_regulation of Gene_expression of Vtn 1 0.03 1.01 0.53
104 INT133314 Positive_regulation of Binding of SPP1 2 0.22 2.38 0.52
105 INT145225 Transcription of ITGB1 1 0.10 0.1 0.52
106 INT136942 Negative_regulation of Positive_regulation of Prkce 1 0.39 0.66 0.48
107 INT184062 Binding of Jak2 5 0.37 3.13 0.47
108 INT268576 Positive_regulation of Gene_expression of THBS1 2 0.64 2.26 0.47
109 INT261817 Protein_catabolism of Ccdc80 1 0.02 0.86 0.45
110 INT205890 Transcription of Jak2 1 0.41 0.22 0.43
111 INT203728 Regulation of Binding of Thbs1 1 0.33 2.76 0.42
112 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41
113 INT203726 Regulation of Thbs1 2 0.33 1.41 0.41
114 INT127976 Negative_regulation of Regulation of SPP1 1 0.37 1.62 0.41
115 INT107462 Localization of Jak2 2 0.60 0.78 0.4
116 INT289704 Protein_catabolism of Spp1 5 0.27 2.42 0.39
117 INT229697 Negative_regulation of Phosphorylation of Jak2 1 0.15 0.54 0.39
118 INT121141 Transcription of Spp1 6 0.34 5.02 0.38
119 INT147227 Positive_regulation of Ccdc80 1 0.01 0.08 0.38
120 INT130927 Negative_regulation of Thbs1 19 0.59 3.72 0.36
121 INT51340 Binding of Vtn 2 0.22 1.38 0.36
122 INT200786 Positive_regulation of Gene_expression of Jak2 9 0.69 6.03 0.35
123 INT176519 Regulation of Gene_expression of Spp1 7 0.58 8.54 0.35
124 INT205910 Negative_regulation of Positive_regulation of Jak2 1 0.33 0.26 0.35
125 INT329301 Phosphorylation of Spp1 1 0.62 1.71 0.34
126 INT185830 Positive_regulation of Localization of SPP1 2 0.50 3.39 0.33
127 INT119073 Negative_regulation of ITGB1 1 0.01 0.1 0.33
128 INT88134 Negative_regulation of Gene_expression of Spp1 2 0.41 1.94 0.32
129 INT58185 Binding of Itga3 1 0.12 2.79 0.3
130 INT179813 Regulation of Nid1 1 0.33 0 0.29
131 INT176518 Positive_regulation of Positive_regulation of Spp1 5 0.47 3.36 0.28
132 INT35283 Negative_regulation of Vtn 2 0.21 0.34 0.27
133 INT185828 Phosphorylation of SPP1 1 0.62 1.36 0.26
134 INT303972 Positive_regulation of Gene_expression of JAK2 2 0.63 1.3 0.24
135 INT248262 Negative_regulation of Positive_regulation of Spp1 1 0.04 0.65 0.24
136 INT97129 Transcription of SPP1 4 0.51 0.67 0.23
137 INT130368 Transcription of Thbs1 2 0.69 1.39 0.23
138 INT185826 Negative_regulation of Gene_expression of SPP1 1 0.42 0.8 0.23
139 INT130360 Positive_regulation of Transcription of Thbs1 1 0.46 1.41 0.23
140 INT140639 Gene_expression of FOXF1 3 0.52 0.89 0.22
141 INT140351 Binding of Prkce 2 0.28 0.32 0.22
142 INT169685 Regulation of Positive_regulation of Prkce 1 0.61 0.36 0.22
143 INT88131 Negative_regulation of Spp1 3 0.56 0.7 0.21
144 INT222635 Gene_expression of Thbs1 4 0.39 15.2 0.2
145 INT225973 Binding of Itgb1 2 0.08 1.1 0.2
146 INT245860 Gene_expression of Itgb1 8 0.42 5.37 0.19
147 INT178504 Positive_regulation of Localization of THBS1 2 0.05 1.9 0.19
148 INT24818 Positive_regulation of Binding of VTN 1 0.49 0 0.18
149 INT176522 Negative_regulation of Localization of Spp1 3 0.37 2.65 0.17
150 INT273031 Transcription of Vtn 1 0.12 0.81 0.17
151 INT328811 Negative_regulation of Localization of Jak2 1 0.34 0.13 0.17
152 INT200802 Regulation of Jak2 5 0.61 2.86 0.16
153 INT231474 Binding of THBS1 4 0.34 2.04 0.16
154 INT196355 Protein_catabolism of NID1 1 0.11 0.39 0.16
155 INT251385 Binding of Fbln2 1 0.06 0 0.16
156 INT196358 Positive_regulation of Localization of NID1 1 0.06 0.44 0.16
157 INT196356 Localization of NID1 1 0.09 0.44 0.16
158 INT196354 Negative_regulation of Localization of NID1 1 0.05 0.44 0.16
159 INT348150 Binding of Thbs1 1 0.24 2.06 0.15
160 INT110105 Positive_regulation of Localization of Dmp1 1 0.48 0 0.14
161 INT249096 Regulation of FOXF1 1 0.19 0.28 0.14
162 INT110103 Negative_regulation of Dmp1 1 0.41 0 0.14
163 INT110098 Negative_regulation of Localization of Dmp1 1 0.41 0 0.14
164 INT58183 Negative_regulation of Itga3 1 0.18 1.2 0.13
165 INT110101 Localization of Dmp1 1 0.71 0 0.13
166 INT222042 Localization of ITGB1 3 0.29 0.72 0.12
167 INT278143 Positive_regulation of Negative_regulation of Jak2 1 0.16 0.54 0.11
168 INT282445 Negative_regulation of Binding of Vtn 1 0.15 0.63 0.11
169 INT88936 Positive_regulation of Regulation of SPP1 1 0.40 1.1 0.11
170 INT348149 Regulation of Gene_expression of Thbs1 1 0.31 1.94 0.1
171 INT348145 Localization of Thbs1 1 0.41 6.72 0.1
172 INT213448 Localization of FOXF1 1 0.58 0.15 0.1
173 INT312354 Regulation of Gene_expression of JAK2 1 0.25 1.17 0.1
174 INT321952 Protein_catabolism of Vtn 1 0.11 0.68 0.1
175 INT200792 Regulation of Gene_expression of Jak2 5 0.61 5.69 0.09
176 INT64708 Negative_regulation of Gene_expression of VTN 1 0.37 0.44 0.09
177 INT109463 Regulation of Dmp1 1 0.16 0 0.09
178 INT184018 Negative_regulation of Protein_catabolism of Jak2 1 0.36 1.76 0.08
179 INT184023 Protein_catabolism of Jak2 1 0.61 1.75 0.08
180 INT144708 Regulation of Gene_expression of Spp1 1 0.04 0.32 0.08
181 INT213440 Negative_regulation of FOXF1 1 0.33 0.14 0.08
182 INT158611 Negative_regulation of Binding of Vtn 1 0.04 0.48 0.08
183 INT184552 Regulation of Spp1 1 0.17 1.55 0.08
184 INT222588 Negative_regulation of Gene_expression of Thbs1 2 0.30 7.93 0.07
185 INT179792 Gene_expression of Nid1 1 0.56 0.21 0.07
186 INT310747 Regulation of JAK2 2 0.33 1.58 0.05
187 INT238202 Negative_regulation of Localization of JAK2 1 0.09 0 0.05
188 INT238200 Localization of JAK2 1 0.16 0 0.05
189 INT335516 Transcription of EDIL3 1 0.52 0.85 0.05
190 INT222624 Negative_regulation of Thbs1 2 0.30 8.42 0.04
191 INT155305 Positive_regulation of Transcription of SPP1 2 0.11 0.29 0.04
192 INT99763 Regulation of Thbs1 2 0.23 2.08 0.04
193 INT277163 Gene_expression of Vtn 1 0.02 1.05 0.04
194 INT179815 Positive_regulation of Gene_expression of Nid1 1 0.50 0 0.04
195 INT348152 Positive_regulation of Localization of Thbs1 1 0.24 0.85 0.04
196 INT348157 Regulation of Transcription of Thbs1 1 0.14 0.96 0.04
197 INT348147 Transcription of Thbs1 1 0.27 0.96 0.04
198 INT294469 Transcription of THBS1 2 0.66 0.46 0.03
199 INT238199 Positive_regulation of Positive_regulation of JAK2 1 0.10 0 0.03
200 INT231690 Negative_regulation of Binding of THBS1 1 0.16 0.37 0.03
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