GO:0010839

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Name negative regulation of keratinocyte proliferation
Categary Process
Go Slim No
Go Link GO:0010839
Unique Molecular Interactions 76
Total Molecular Interactions 120
Total Single Events 651
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of keratinocyte proliferation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of keratinocyte proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
2 INT171990 Binding of DMD and VDR 5 0.05 2.58 0.39
3 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29
4 INT238632 Binding of EPB41 and Cask 1 0.44 0.78 0.27
5 INT330976 Igh-Dex Positive_regulation of Gene_expression of VDR 1 0.01 1.11 0.23
6 INT262151 Vdr Regulation of Cyp24a1 1 0.24 0.24 0.23
7 INT197647 DPH1 Negative_regulation of VDR 1 0.02 0.58 0.18
8 INT335018 Vdr Positive_regulation of Gene_expression of Fgf23 1 0.44 0.36 0.17
9 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15
10 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
11 INT333765 Positive_regulation of Vdr Regulation of Gene_expression of Ccr6 1 0.21 0.48 0.12
12 INT166723 Binding of Vdr and Rxrb 1 0.11 0.31 0.09
13 INT267156 Binding of VDR and SUGT1 1 0.04 3.4 0.09
14 INT166724 Binding of Vdr and Rxra 1 0.28 0.32 0.09
15 INT330955 HOMER1 Positive_regulation of Gene_expression of VDR 1 0.01 0.99 0.08
16 INT262216 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Vdr 1 0.29 0.44 0.08
17 INT238631 Regulation of Binding of EPB41 and Cask 1 0.29 0.24 0.07
18 INT197649 NR1I2 Positive_regulation of VDR 1 0.15 0.54 0.07
19 INT197648 ESRRB Positive_regulation of VDR 1 0.03 0.54 0.07
20 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
21 INT339272 VDR Positive_regulation of Gene_expression of KRT20 1 0.00 0.07 0.05
22 INT182936 HGFAC Positive_regulation of VDR 1 0.00 0.06 0.05
23 INT182914 KCNIP3 Positive_regulation of VDR 1 0.40 0.06 0.05
24 INT238622 Binding of Grin2d and Cask 1 0.05 0 0.04
25 INT262196 Nr1i2 Negative_regulation of Vdr 1 0.27 0.14 0.04
26 INT233849 Twist1 Positive_regulation of Snai2 1 0.07 0.58 0.04
27 INT262166 Binding of Nr1i2 and Vdr 1 0.23 0.14 0.04
28 INT233853 Zeb1 Positive_regulation of Snai2 1 0.09 0.58 0.04
29 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
30 INT262154 Vdr Negative_regulation of Cyp24a1 1 0.16 0.14 0.04
31 INT297375 Binding of VDR and Rxra 1 0.02 0.2 0.03
32 INT264382 NR1H4 Positive_regulation of VDR 1 0.04 0.09 0.03
33 INT182950 Binding of VDR and NR1H4 5 0.03 1.16 0
34 INT182949 Binding of RARA and VDR 1 0.20 0 0
35 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
36 INT182942 VDR Positive_regulation of CDKN1A 1 0.35 0.38 0
37 INT238578 Binding of Cask and Sumo1 1 0.26 0.33 0
38 INT238577 Binding of Cask and Sumo2 1 0.13 0 0
39 INT342385 Positive_regulation of Binding of Lrp5 and Vdr 1 0.53 0.98 0
40 INT330958 Binding of VDR and BTG2 1 0.07 0.51 0
41 INT238572 Negative_regulation of Binding of Cask and Sumo1 1 0.23 0.33 0
42 INT342378 Binding of Vdr and Best1 1 0.05 0.4 0
43 INT238575 Binding of Cask and Magi1 1 0.04 0.17 0
44 INT354923 Binding of VDR and Uvbs1 1 0.00 0.83 0
45 INT177262 Binding of MED1 and SV2A 1 0.23 0 0
46 INT183016 Binding of VDR and Dre 1 0.01 0.12 0
47 INT342265 Binding of VDR and HHIP 1 0.00 0.93 0
48 INT182955 Positive_regulation of Binding of VDR and NR1H4 1 0.03 0 0
49 INT182940 Binding of VDR and TNFRSF25 1 0.22 0.21 0
50 INT245733 Binding of VDR and DISC1 1 0.03 0.75 0
51 INT182926 VDR Positive_regulation of HNF4A 1 0.02 0.09 0
52 INT338190 Binding of PCa and VDR 1 0.00 0.84 0
53 INT238570 Regulation of Binding of Cask and Magi1 1 0.03 0.17 0
54 INT342381 Binding of Lrp5 and Vdr 1 0.55 0.97 0
55 INT342388 Binding of CALCR and Vdr 1 0.12 0.83 0
56 INT225481 Binding of Med1 and Acp5 1 0.16 0 0
57 INT182939 Binding of DR1 and VDR 1 0.12 0 0
58 INT182920 Binding of PDYN and VDR 1 0.12 0.07 0
59 INT177286 Binding of CXADR and MED1 1 0.27 0 0
60 INT330959 Binding of RXRB and VDR 1 0.05 0.14 0
61 INT182953 Binding of VDR and KCNIP3 1 0.24 0.1 0
62 INT238579 Binding of Cask and Sumo3 1 0.15 0 0
63 INT182959 Binding of VDR and TNFRSF10B 1 0.16 0 0
64 INT225578 Binding of Vdr and Pprc1 1 0.00 0 0
65 INT182962 TGFBI Regulation of VDR 1 0.42 0.08 0
66 INT330957 Binding of TEP1 and VDR 1 0.01 1.07 0
67 INT225541 Binding of Med1 and Tpr 1 0.00 0.07 0
68 INT291711 Rxra Positive_regulation of VDR 1 0.09 0 0
69 INT182917 Binding of VDR and Positive_regulation of Gene_expression of CDKN1A 1 0.35 0.31 0
70 INT238623 Binding of Cask and Cadm1 1 0.09 0.08 0
71 INT177280 Binding of MED1 and FAUP1 1 0.01 0 0
72 INT238621 Binding of Sdc2 and Cask 1 0.06 0.08 0
73 INT182928 VDR Regulation of PDYN 1 0.09 0.07 0
74 INT182931 VDR Positive_regulation of Gene_expression of CDKN1A 1 0.48 0.86 0
75 INT197643 TNF Regulation of VDR 1 0.04 1.67 0
76 INT238630 Negative_regulation of Binding of EPB41 and Cask 1 0.45 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of keratinocyte proliferation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of keratinocyte proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT119700 Gene_expression of VDR 88 0.75 65.33 11.5
2 INT123701 Negative_regulation of VDR 61 0.59 48.94 9.67
3 INT156850 Binding of VDR 40 0.47 24.86 4.87
4 INT160633 Gene_expression of Vdr 21 0.77 10.01 2.73
5 INT102638 Regulation of VDR 21 0.44 9.92 2.54
6 INT102639 Positive_regulation of VDR 31 0.69 18.05 2.38
7 INT238608 Gene_expression of Cask 1 0.73 2.74 1.9
8 INT112214 Gene_expression of Vdr 4 0.33 3.59 1.11
9 INT182968 Positive_regulation of Gene_expression of VDR 22 0.58 15.22 0.89
10 INT262107 Binding of Vdr 9 0.48 6.56 0.71
11 INT183009 Phosphorylation of VDR 3 0.68 1 0.68
12 INT262060 Positive_regulation of Vdr 8 0.58 2.84 0.67
13 INT287118 Negative_regulation of Gene_expression of VDR 3 0.36 3.53 0.66
14 INT238602 Binding of Cask 1 0.40 0.9 0.63
15 INT177337 Localization of VDR 6 0.73 3.44 0.59
16 INT124270 Positive_regulation of Gene_expression of Vdr 2 0.29 1.1 0.58
17 INT238589 Phosphorylation of Cask 1 0.77 0.13 0.52
18 INT119708 Transcription of VDR 11 0.71 5.43 0.48
19 INT112215 Binding of Vdr 4 0.31 2.43 0.44
20 INT160642 Positive_regulation of Gene_expression of Vdr 5 0.62 1.61 0.42
21 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
22 INT233917 Gene_expression of MED1 2 0.20 0.17 0.38
23 INT238618 Positive_regulation of Cask 1 0.66 0.4 0.35
24 INT262063 Localization of Vdr 3 0.75 1.76 0.33
25 INT238592 Positive_regulation of Phosphorylation of Cask 1 0.41 0 0.31
26 INT106734 Phosphorylation of MED1 4 0.74 1.65 0.28
27 INT145009 Positive_regulation of Negative_regulation of VDR 2 0.41 1.18 0.25
28 INT102637 Positive_regulation of Vdr 3 0.48 2.82 0.24
29 INT262040 Negative_regulation of Gene_expression of Vdr 1 0.25 0.26 0.21
30 INT238611 Localization of Cask 1 0.76 0.67 0.18
31 INT238597 Positive_regulation of Gene_expression of Cask 1 0.66 0.88 0.17
32 INT160641 Transcription of Vdr 5 0.71 3.1 0.16
33 INT106730 Regulation of Phosphorylation of MED1 2 0.24 0.7 0.16
34 INT149951 Negative_regulation of Transcription of VDR 3 0.43 1.19 0.13
35 INT238613 Negative_regulation of Gene_expression of Cask 1 0.41 0.12 0.12
36 INT106731 Negative_regulation of Phosphorylation of MED1 1 0.02 0.96 0.12
37 INT333738 Regulation of Positive_regulation of Vdr 1 0.38 0.48 0.12
38 INT238590 Negative_regulation of Binding of Cask 1 0.41 0.23 0.1
39 INT238615 Positive_regulation of Binding of Cask 1 0.47 0.06 0.09
40 INT178814 Regulation of Binding of VDR 2 0.38 0.57 0.08
41 INT156864 Positive_regulation of Phosphorylation of MED1 1 0.45 0 0.07
42 INT211082 Regulation of Positive_regulation of Vdr 1 0.30 1.18 0.07
43 INT238588 Regulation of Binding of Cask 1 0.43 0.15 0.07
44 INT119703 Regulation of Gene_expression of VDR 4 0.44 2.43 0.06
45 INT211079 Positive_regulation of Positive_regulation of Vdr 1 0.33 0.59 0.05
46 INT262079 Negative_regulation of Vdr 2 0.42 0.71 0.04
47 INT339273 Negative_regulation of Binding of VDR 1 0.21 0.07 0.04
48 INT354920 Negative_regulation of Positive_regulation of VDR 1 0.21 1.96 0.04
49 INT211080 Negative_regulation of Positive_regulation of Vdr 1 0.29 0.6 0.04
50 INT354921 Positive_regulation of Localization of VDR 1 0.23 0.79 0.03
51 INT307189 Localization of Med1 3 0.53 0.32 0
52 INT225400 Positive_regulation of Gene_expression of Med1 2 0.35 0.82 0
53 INT119701 Regulation of Transcription of VDR 2 0.61 0.57 0
54 INT225358 Negative_regulation of Gene_expression of Med1 2 0.30 1.16 0
55 INT177336 Positive_regulation of Binding of MED1 1 0.24 0 0
56 INT182982 Positive_regulation of Phosphorylation of VDR 1 0.42 0 0
57 INT288196 Negative_regulation of Transcription of Vdr 1 0.23 0 0
58 INT307197 Negative_regulation of Med1 1 0.30 0.7 0
59 INT306016 Positive_regulation of Positive_regulation of VDR 1 0.20 1.26 0
60 INT297368 Regulation of Positive_regulation of VDR 1 0.27 1.66 0
61 INT238601 Protein_catabolism of Cask 1 0.62 0 0
62 INT307188 Transcription of Med1 1 0.48 0.7 0
63 INT238593 Negative_regulation of Cask 1 0.41 0.32 0
64 INT140704 Transcription of Vdr 1 0.12 0.38 0
65 INT322591 Regulation of Negative_regulation of VDR 1 0.16 1.29 0
66 INT225389 Regulation of Binding of Med1 1 0.17 0.07 0
67 INT177320 Binding of MED1 1 0.25 0 0
68 INT171996 Regulation of Regulation of VDR 1 0.44 0.05 0
69 INT225457 Binding of Med1 1 0.35 0.28 0
70 INT238594 Positive_regulation of Localization of Cask 1 0.44 0 0
71 INT238600 Regulation of Cask 1 0.43 0.06 0
72 INT341851 Positive_regulation of MED1 1 0.01 0.5 0
73 INT308354 Gene_expression of Snai2 1 0.58 1.14 0
74 INT308358 Positive_regulation of Gene_expression of Snai2 1 0.45 1.14 0
75 INT342376 Positive_regulation of Binding of Vdr 1 0.46 0.86 0
76 INT334482 Regulation of Gene_expression of Med1 1 0.17 0.1 0
77 INT160644 Positive_regulation of Transcription of Vdr 1 0.62 0 0
78 INT305345 Positive_regulation of Snai2 1 0.16 1.4 0
79 INT334481 Negative_regulation of Localization of Med1 1 0.16 0.09 0
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