GO:0010875

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Name positive regulation of cholesterol efflux
Categary Process
Go Slim No
Go Link GO:0010875
Unique Molecular Interactions 475
Total Molecular Interactions 685
Total Single Events 4290
Pain Genes Associated 25

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cholesterol efflux. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of cholesterol efflux. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT131257 ITIH4 Positive_regulation of Gene_expression of Nfkbia 1 0.23 1.41 2.3
2 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
3 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31
4 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
5 INT129034 Nfkbia Positive_regulation of Nfkb1 1 0.02 0.67 0.89
6 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
7 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
8 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
9 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
10 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
11 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
12 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
13 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
14 INT125543 Arsa Negative_regulation of Phosphorylation of Nfkbia 1 0.00 0.52 0.68
15 INT178334 Binding of Pon1 and Chdh 1 0.11 11.45 0.66
16 INT233669 gr Positive_regulation of Transcription of Nfkbia 1 0.26 0.33 0.64
17 INT139079 Tnip1 Negative_regulation of Ptch1 1 0.20 0.63 0.62
18 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
19 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
20 INT83424 Binding of CD40LG and ADIPOQ 2 0.13 1 0.59
21 INT83426 ADIPOQ Negative_regulation of Binding of CD40LG 2 0.21 1 0.59
22 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
23 INT334013 Ccl25 Positive_regulation of Gene_expression of Lrp1 1 0.07 0.98 0.56
24 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
25 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
26 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52
27 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
28 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
29 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
30 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
31 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
32 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
33 INT146113 Binding of Adra2a and Lrp1 1 0.01 1.07 0.48
34 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
35 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
36 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
37 INT87934 Phosphorylation of Nfkbia Positive_regulation of Nfkb1 1 0.02 0.1 0.45
38 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
39 INT87936 Nfkbia Positive_regulation of Nfkb1 1 0.03 0.1 0.44
40 INT83423 ADIPOQ Negative_regulation of Binding of IGHG3 1 0.02 0.31 0.42
41 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
42 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
43 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4
44 INT296945 ADIPOQ Negative_regulation of TNF 1 0.03 1.13 0.4
45 INT207113 Nfkbia Negative_regulation of Nfkb1 1 0.11 0.96 0.4
46 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
47 INT316672 Binding of LRP1 and SFTPD 1 0.35 0.96 0.37
48 INT240616 Binding of SHBG and ADIPOQ 1 0.31 4.43 0.37
49 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
50 INT253147 Positive_regulation of Nr1h2 Negative_regulation of Positive_regulation of Ptpn1 1 0.17 0.61 0.33
51 INT253142 Positive_regulation of Nr1h2 Negative_regulation of Gene_expression of Mmp9 1 0.05 0.6 0.33
52 INT108879 Negative_regulation of PTGS2 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.43 0.31
53 INT239344 Nr1h2 Positive_regulation of Gene_expression of Srebf1 1 0.26 0.84 0.29
54 INT239324 Nr1h2 Positive_regulation of Hltf 1 0.04 0.78 0.29
55 INT239347 Nr1h2 Positive_regulation of Srebf1 1 0.26 0.78 0.29
56 INT143724 Binding of Ikbkg and Nfkbia 1 0.02 0.79 0.29
57 INT239329 Nr1h2 Positive_regulation of Gene_expression of Hltf 1 0.04 0.84 0.29
58 INT143723 Positive_regulation of Binding of Ikbkg and Nfkbia 1 0.02 0.8 0.29
59 INT239336 Nr1h2 Positive_regulation of Gene_expression of Fas 1 0.07 0.84 0.29
60 INT109098 Binding of ABL2 and PON1 1 0.36 1.32 0.28
61 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
62 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
63 INT240626 Binding of ADIPOQ and Hdlcl1 1 0.02 3.27 0.28
64 INT80873 Positive_regulation of Nfkb1 Positive_regulation of Protein_catabolism of Nfkbia 2 0.01 0.58 0.27
65 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
66 INT108878 ZNF236 Regulation of Protein_catabolism of Nfkbia 1 0.00 0.38 0.26
67 INT108880 ZNF236 Regulation of Gene_expression of Nfkbia 1 0.00 0.38 0.26
68 INT108877 ZNF236 Regulation of Phosphorylation of Nfkbia 1 0.00 0.38 0.26
69 INT312768 Pon1 Negative_regulation of Gene_expression of Ccl2 1 0.06 1.42 0.26
70 INT108881 ZNF236 Regulation of Transcription of Nfkbia 1 0.00 0.36 0.26
71 INT220635 Binding of Lrp1 and Kat5 2 0.09 0.71 0.25
72 INT139357 Nr1h2 Regulation of Gene_expression of Ptges 1 0.07 0.5 0.25
73 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
74 INT198926 Binding of Apbb1 and Lrp1 5 0.12 2.18 0.24
75 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
76 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
77 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
78 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
79 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
80 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
81 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
82 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23
83 INT179492 Binding of Ins1 and Adipoq 1 0.16 1.16 0.23
84 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
85 INT144241 CGA Negative_regulation of Phosphorylation of NFKBIA 1 0.10 0.34 0.22
86 INT249760 Positive_regulation of Cnr1 Negative_regulation of Gene_expression of Adipoq 1 0.20 0.81 0.22
87 INT144244 TNF Positive_regulation of Protein_catabolism of NFKBIA 1 0.28 0.34 0.22
88 INT144253 TNF Positive_regulation of Phosphorylation of NFKBIA 1 0.39 0.34 0.22
89 INT260397 Positive_regulation of Hmox1 Positive_regulation of Gene_expression of Adipoq 1 0.37 0.78 0.22
90 INT144247 CGA Positive_regulation of Protein_catabolism of NFKBIA 1 0.11 0.34 0.22
91 INT144243 CGA Positive_regulation of Phosphorylation of NFKBIA 1 0.11 0.34 0.22
92 INT242996 Adipoq Negative_regulation of Transcription of Cd68 1 0.22 0.6 0.21
93 INT242994 Adipoq Negative_regulation of Spp1 1 0.19 0.59 0.21
94 INT332304 Binding of Il6 and Adipoq 1 0.03 0.4 0.2
95 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
96 INT145886 Binding of CXCL1 and Adipoq 1 0.00 0.77 0.2
97 INT352518 Binding of FAT1 and Adipoq 1 0.01 2.79 0.2
98 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
99 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19
100 INT260394 Positive_regulation of Hmox1 Positive_regulation of Adipoq 1 0.37 0.78 0.19
101 INT159788 Tnf Positive_regulation of Phosphorylation of Nfkbia 1 0.01 0.39 0.19
102 INT334394 ADIPOQ Negative_regulation of Gene_expression of Tnf 1 0.37 1.06 0.18
103 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
104 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
105 INT207186 Binding of Adipoq and Bmi1 1 0.01 1.65 0.18
106 INT228168 Adipoq Positive_regulation of Prkag1 2 0.05 1.08 0.17
107 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
108 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17
109 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17
110 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
111 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
112 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
113 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17
114 INT207350 TBXA2R Regulation of Gene_expression of ABCA1 1 0.10 0 0.17
115 INT190635 Binding of Lmo2 and Nr1h2 1 0.09 0.59 0.16
116 INT122528 Apoe Regulation of Eno2 1 0.05 0.29 0.16
117 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16
118 INT207338 Negative_regulation of CPOX Negative_regulation of ABCA1 1 0.11 0 0.16
119 INT297345 Apoe Negative_regulation of Csf2 1 0.17 0.66 0.16
120 INT289525 Sirt1 Negative_regulation of Negative_regulation of Ucp2 1 0.32 0.86 0.15
121 INT240622 Binding of ADIPOQ and Etv3 1 0.04 1.32 0.15
122 INT335459 ABCA1 Positive_regulation of ITPR3 1 0.00 0 0.15
123 INT312794 Hdl1 Regulation of Pon1 1 0.02 1.63 0.15
124 INT157275 Binding of PRKAA1 and Adipoq 1 0.01 1.13 0.15
125 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14
126 INT207360 PTGDS Negative_regulation of Negative_regulation of ABCA1 1 0.25 0 0.14
127 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14
128 INT207337 PTGER2 Negative_regulation of Negative_regulation of ABCA1 1 0.04 0 0.14
129 INT207353 ZNF398 Regulation of ABCA1 1 0.00 0 0.14
130 INT239355 Binding of Nr1h2 and Positive_regulation of Gene_expression of CETP 1 0.17 3.75 0.14
131 INT157273 Adipoq Positive_regulation of PRKAA1 1 0.03 1.16 0.14
132 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14
133 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14
134 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13
135 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
136 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12
137 INT270663 Adipoq Positive_regulation of Il6 1 0.02 1.05 0.12
138 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12
139 INT179493 Adipoq Positive_regulation of Ins1 1 0.20 0.99 0.12
140 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12
141 INT270669 Adipoq Positive_regulation of IL8 1 0.01 1.06 0.12
142 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
143 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
144 INT270665 Adipoq Positive_regulation of Ccl2 1 0.07 1.06 0.12
145 INT164746 Binding of LEP and Adipoq 1 0.07 0.69 0.12
146 INT228175 RNU1-1 Regulation of Adipoq 1 0.11 0.78 0.12
147 INT139790 PRSS53 Negative_regulation of Phosphorylation of NFKBIA 1 0.01 0.9 0.11
148 INT306265 Binding of NFKB1 and NFKBIA 1 0.21 0.48 0.11
149 INT293236 IDO1 Regulation of ABCA1 1 0.00 0 0.11
150 INT257467 Fat1 Regulation of Gene_expression of Adipoq 1 0.08 0.56 0.11
151 INT139789 TNFAIP8 Positive_regulation of Phosphorylation of NFKBIA 1 0.02 0.89 0.11
152 INT139788 TNFAIP8 Positive_regulation of NFKBIA 1 0.01 0.88 0.11
153 INT312792 Binding of Pon1 and Hdl1 1 0.04 1.85 0.11
154 INT208361 Positive_regulation of Binding of Apoe and Hdl1 1 0.12 1.22 0.1
155 INT240624 Binding of ADIPOQ and Hdl1 1 0.02 0.85 0.1
156 INT297346 Apoe Negative_regulation of Localization of TNF 1 0.48 0.26 0.1
157 INT262996 ADIPOQ Regulation of INS 1 0.13 1.25 0.1
158 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
159 INT263449 Binding of NFKBIA and TBK1 1 0.07 0.2 0.1
160 INT310275 Negative_regulation of Binding of Adipoq and Ins1 1 0.19 1.14 0.09
161 INT157276 PPARG Positive_regulation of Adipoq 1 0.29 1.09 0.09
162 INT42224 ABCA1 Positive_regulation of CYBB 1 0.01 0 0.09
163 INT157274 Adipoq Positive_regulation of ADIPOR1 1 0.00 1.2 0.09
164 INT308666 Binding of Lrp1 and Chol1 1 0.10 0.69 0.09
165 INT310274 Binding of Adipoq and Ins1 1 0.21 1.14 0.09
166 INT263450 NFKB2 Positive_regulation of Protein_catabolism of NFKBIA 1 0.17 0.17 0.09
167 INT289539 Negative_regulation of Sirt1 Negative_regulation of Gene_expression of Agrp 1 0.29 0.47 0.09
168 INT42225 Binding of ABCA1 and DECR1 1 0.02 0 0.08
169 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
170 INT270457 Binding of Ptch1 and Gli1 1 0.02 1.3 0.08
171 INT228174 RNU1-1 Positive_regulation of Gene_expression of Adipoq 1 0.12 0.55 0.08
172 INT289536 Sirt1 Negative_regulation of Localization of Pparg 1 0.13 0.43 0.08
173 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
174 INT190636 Nr1h2 Positive_regulation of Rnf115 1 0.20 0.71 0.08
175 INT257466 Psd Negative_regulation of Gene_expression of Adipoq 1 0.22 0.66 0.08
176 INT267154 ADIPOQ Regulation of Positive_regulation of SUGT1 1 0.03 1.18 0.08
177 INT289603 Sirt1 Negative_regulation of Localization of PPARG 1 0.02 0.43 0.08
178 INT289540 Sirt1 Negative_regulation of Localization of Ins1 1 0.03 0.43 0.08
179 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07
180 INT352517 Binding of INS and Adipoq 1 0.09 1.32 0.07
181 INT297330 Apoe Positive_regulation of Gene_expression of Nos2 1 0.26 0.34 0.07
182 INT289258 Binding of ABCA1 and Il6ra 1 0.00 0.33 0.07
183 INT289533 Sirt1 Negative_regulation of Pparg 1 0.18 0.42 0.07
184 INT262997 Binding of HSD11B1 and ADIPOQ 1 0.54 2.82 0.07
185 INT229330 Binding of Nr1h2 and Positive_regulation of Gene_expression of GCK 1 0.01 0.62 0.07
186 INT229333 Binding of Nr1h2 and Positive_regulation of Gene_expression of SLC2A4 1 0.02 0.62 0.07
187 INT256160 Positive_regulation of Binding of Pgc and Sirt1 1 0.55 0.21 0.07
188 INT289602 Sirt1 Negative_regulation of PPARG 1 0.02 0.37 0.07
189 INT308655 Binding of Lrp1 and Gopc 1 0.01 0.49 0.07
190 INT256161 Binding of Pgc and Sirt1 1 0.38 0.21 0.07
191 INT260392 Hmox1 Positive_regulation of Adipoq 1 0.32 0.65 0.07
192 INT308665 Binding of Apoe and Gopc 1 0.02 0.49 0.07
193 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07
194 INT336380 Gene_expression of Adipoq Positive_regulation of Ppara 1 0.06 1.77 0.07
195 INT50078 Binding of APOE and NPPA 1 0.30 0.42 0.07
196 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
197 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06
198 INT262187 Nr1i2 Positive_regulation of Gene_expression of Abcg1 1 0.24 0.21 0.06
199 INT140813 Binding of Retn and Adipoq 1 0.03 1.18 0.06
200 INT293233 IDO1 Positive_regulation of ABCA1 1 0.01 0 0.06

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cholesterol efflux. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of cholesterol efflux. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
2 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
3 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
4 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
5 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
6 INT81538 Phosphorylation of Nfkbia 27 0.62 8.86 10.49
7 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
8 INT80872 Protein_catabolism of Nfkbia 28 0.92 10.56 8.62
9 INT95297 Gene_expression of Nfkbia 14 0.68 7.61 8.24
10 INT81532 Negative_regulation of Protein_catabolism of Nfkbia 21 0.54 8.92 7.38
11 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
12 INT93481 Negative_regulation of Protein_catabolism of Nfkbia 14 0.39 7.24 7.21
13 INT88498 Protein_catabolism of Nfkbia 14 0.82 6.94 7.1
14 INT197493 Localization of Apoe 61 0.79 27.48 7.06
15 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
16 INT81541 Negative_regulation of Nfkbia 12 0.51 5.73 6.79
17 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
18 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
19 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
20 INT63042 Binding of Apoe 59 0.48 31.23 5.88
21 INT47976 Protein_catabolism of NFKBIA 17 0.88 7.57 5.79
22 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
23 INT81535 Negative_regulation of Phosphorylation of Nfkbia 15 0.44 5.74 5.18
24 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
25 INT143234 Gene_expression of Nfkbia 10 0.62 5.2 5.02
26 INT88496 Positive_regulation of Protein_catabolism of Nfkbia 8 0.53 3.05 4.78
27 INT2848 Localization of ABCA1 23 0.70 10.64 4.73
28 INT131253 Positive_regulation of Gene_expression of Nfkbia 4 0.41 3.28 4.71
29 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
30 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
31 INT3128 Negative_regulation of PON1 30 0.59 26.19 4.57
32 INT28662 Gene_expression of PON1 19 0.65 16.46 4.49
33 INT87210 Positive_regulation of Nfkbia 9 0.61 3.89 4.35
34 INT81543 Positive_regulation of Phosphorylation of Nfkbia 7 0.37 2.51 4.1
35 INT108868 Transcription of Nfkbia 2 0.57 2.91 4.03
36 INT176208 Gene_expression of Nr1h2 27 0.59 22.75 3.84
37 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
38 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
39 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
40 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67
41 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58
42 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
43 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39
44 INT72141 Binding of Apoe 11 0.37 10.91 3.27
45 INT28130 Positive_regulation of ABCA1 18 0.61 7.08 3.22
46 INT97710 Localization of Apoe 1 0.79 7.18 3.2
47 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1
48 INT597 Positive_regulation of PON1 26 0.62 19.14 2.87
49 INT233606 Transcription of Nfkbia 1 0.66 1.55 2.71
50 INT93401 Positive_regulation of Protein_catabolism of Nfkbia 11 0.46 3.89 2.7
51 INT107968 Positive_regulation of NFKBIA 9 0.46 5.27 2.69
52 INT47974 Negative_regulation of Protein_catabolism of NFKBIA 7 0.49 2.38 2.69
53 INT50080 Binding of APOE 38 0.45 29.61 2.67
54 INT204340 Localization of ADIPOQ 20 0.75 25.18 2.64
55 INT108869 Localization of Nfkbia 5 0.56 1.04 2.63
56 INT26974 Negative_regulation of Adipoq 27 0.52 26.01 2.59
57 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
58 INT122003 Phosphorylation of NFKBIA 9 0.59 5.44 2.51
59 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47
60 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
61 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
62 INT122561 Negative_regulation of Gene_expression of Adipoq 12 0.56 14.02 2.26
63 INT135451 Positive_regulation of Positive_regulation of Adipoq 3 0.40 2.06 2.24
64 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
65 INT3723 Binding of PON1 9 0.46 5.83 2.13
66 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
67 INT15765 Localization of PON1 8 0.75 3.61 2.08
68 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
69 INT138029 Binding of Adipoq 10 0.40 6.81 2.04
70 INT134633 Localization of Adipoq 9 0.60 6.39 2.03
71 INT129318 Negative_regulation of NFKBIA 10 0.38 6.19 2.02
72 INT26317 Gene_expression of NFKBIA 5 0.45 2.97 1.96
73 INT56080 Transcription of NFKBIA 2 0.40 2.16 1.93
74 INT198885 Gene_expression of Lrp1 33 0.57 10.2 1.91
75 INT176173 Positive_regulation of Nr1h2 19 0.52 10.95 1.88
76 INT151269 Positive_regulation of Localization of Nfkbia 1 0.37 0 1.86
77 INT207370 Negative_regulation of Gene_expression of ABCA1 1 0.54 2.75 1.78
78 INT227273 Localization of Adipoq 22 0.72 18.04 1.72
79 INT126236 Positive_regulation of Positive_regulation of NFKBIA 4 0.46 2.18 1.69
80 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
81 INT47972 Positive_regulation of Protein_catabolism of NFKBIA 5 0.46 2.09 1.53
82 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
83 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
84 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47
85 INT233612 Regulation of Transcription of Nfkbia 1 0.36 0.55 1.43
86 INT113151 Positive_regulation of Ptch1 7 0.64 3.8 1.41
87 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
88 INT87215 Localization of Nfkbia 5 0.69 1.64 1.39
89 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
90 INT233638 Positive_regulation of Transcription of Nfkbia 1 0.56 1.01 1.33
91 INT139077 Negative_regulation of Ptch1 5 0.56 5.22 1.29
92 INT131254 Positive_regulation of Transcription of Nfkbia 1 0.36 0.99 1.28
93 INT139356 Regulation of Nr1h2 2 0.43 2.95 1.27
94 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
95 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
96 INT166013 Positive_regulation of Gene_expression of NFKBIA 2 0.32 1.15 1.2
97 INT124218 Gene_expression of Pon1 9 0.75 19.55 1.19
98 INT227275 Negative_regulation of Gene_expression of Adipoq 19 0.53 19.51 1.15
99 INT140288 Localization of Pon1 4 0.78 6.15 1.15
100 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14
101 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
102 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
103 INT129726 Regulation of Nfkbia 2 0.06 1.63 1.05
104 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04
105 INT107971 Regulation of NFKBIA 3 0.24 2.03 1.04
106 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
107 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
108 INT81542 Regulation of Protein_catabolism of Nfkbia 2 0.04 0.43 1.02
109 INT198904 Localization of Lrp1 11 0.62 3.25 1.01
110 INT143235 Positive_regulation of Gene_expression of Nfkbia 2 0.56 0.97 1.01
111 INT124220 Binding of Pon1 9 0.47 7.84 0.99
112 INT124198 Negative_regulation of Nfkbia 4 0.37 2.58 0.97
113 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
114 INT81540 Positive_regulation of Nfkbia 4 0.22 1.37 0.92
115 INT160140 Regulation of Binding of Adipoq 1 0.37 0.87 0.92
116 INT198872 Binding of Lrp1 9 0.36 2.73 0.89
117 INT143714 Phosphorylation of Nfkbia 4 0.64 2.94 0.87
118 INT227270 Regulation of Gene_expression of Adipoq 5 0.55 7.35 0.85
119 INT135299 Binding of PTCH1 10 0.48 12.16 0.84
120 INT190089 Binding of Abca1 5 0.36 2.21 0.83
121 INT143720 Negative_regulation of Phosphorylation of Nfkbia 3 0.33 2.68 0.83
122 INT159548 Regulation of Protein_catabolism of Nfkbia 1 0.18 0.62 0.82
123 INT151927 Regulation of Gene_expression of Adipoq 3 0.43 3.32 0.81
124 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
125 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8
126 INT142013 Positive_regulation of Regulation of Adipoq 1 0.03 0.65 0.78
127 INT28020 Binding of Adipoq 10 0.36 11.49 0.77
128 INT233630 Regulation of Nfkbia 1 0.42 0.27 0.76
129 INT233646 Regulation of Localization of Nfkbia 1 0.42 0.27 0.76
130 INT142416 Binding of Ptch1 6 0.34 4.92 0.74
131 INT197495 Negative_regulation of Localization of Apoe 6 0.43 2.19 0.73
132 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72
133 INT303837 Negative_regulation of Pon1 4 0.57 11.08 0.71
134 INT95298 Negative_regulation of Gene_expression of Nfkbia 2 0.38 0.62 0.71
135 INT270428 Negative_regulation of Binding of APOE 2 0.41 1.16 0.7
136 INT113335 Regulation of Transcription of Apoe 1 0.27 0.51 0.7
137 INT81533 Negative_regulation of Negative_regulation of Nfkbia 1 0.04 0.36 0.7
138 INT176180 Negative_regulation of Nr1h2 6 0.16 7.47 0.69
139 INT143719 Negative_regulation of Gene_expression of Nfkbia 2 0.43 1.31 0.68
140 INT176184 Positive_regulation of Gene_expression of Nr1h3 2 0.49 0 0.68
141 INT148756 Regulation of Adipoq 10 0.60 7.83 0.67
142 INT164627 Positive_regulation of Gene_expression of ABCA1 9 0.61 3.95 0.67
143 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67
144 INT176218 Gene_expression of Nr1h3 2 0.65 0 0.67
145 INT229282 Binding of Nr1h2 7 0.17 5.11 0.66
146 INT122061 Negative_regulation of Lrp1 5 0.30 2.47 0.66
147 INT175580 Localization of APOE 10 0.76 18.84 0.65
148 INT166019 Regulation of Gene_expression of NFKBIA 1 0.05 0.64 0.65
149 INT97708 Regulation of Localization of Apoe 1 0.61 2.06 0.62
150 INT118310 Negative_regulation of Positive_regulation of Adipoq 2 0.34 2.47 0.61
151 INT179488 Positive_regulation of Transcription of Adipoq 3 0.37 0.5 0.6
152 INT122004 Negative_regulation of Phosphorylation of NFKBIA 3 0.41 1.59 0.58
153 INT263482 Positive_regulation of Transcription of NFKBIA 1 0.39 0.61 0.57
154 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56
155 INT113334 Positive_regulation of Positive_regulation of Apoe 1 0.50 0.6 0.56
156 INT277710 Regulation of Localization of ABCA1 1 0.04 1.73 0.56
157 INT25362 Binding of NFKBIA 4 0.26 2.52 0.55
158 INT164196 Binding of LRP1 5 0.47 2.59 0.53
159 INT197322 Protein_catabolism of Apoe 6 0.71 3.52 0.51
160 INT186862 Regulation of Pon1 5 0.60 6.15 0.51
161 INT239289 Gene_expression of Abcg1 3 0.31 2.27 0.5
162 INT227272 Transcription of Adipoq 8 0.64 8.29 0.49
163 INT217370 Phosphorylation of Apoe 2 0.63 1.8 0.49
164 INT83430 Positive_regulation of Binding of ADIPOQ 2 0.21 0.85 0.49
165 INT289580 Negative_regulation of Sirt1 23 0.58 9.03 0.48
166 INT240765 Positive_regulation of Pon1 16 0.67 12.06 0.48
167 INT2638 Regulation of PON1 5 0.59 5.13 0.45
168 INT198906 Positive_regulation of Localization of Lrp1 4 0.53 0.51 0.45
169 INT83434 Negative_regulation of Binding of ADIPOQ 1 0.39 1.14 0.45
170 INT300291 Phosphorylation of Sirt1 1 0.77 6.07 0.45
171 INT96816 Regulation of APOE 8 0.45 6.62 0.44
172 INT167468 Regulation of Gene_expression of ABCA1 5 0.52 0.08 0.43
173 INT240935 Transcription of Sirt1 2 0.68 0.42 0.42
174 INT340290 Regulation of Transcription of Sirt1 1 0.43 0.13 0.42
175 INT308980 Positive_regulation of Negative_regulation of Adipoq 3 0.33 2.3 0.4
176 INT97712 Negative_regulation of Transcription of Apoe 1 0.43 1.05 0.4
177 INT209180 Transcription of ABCA1 4 0.47 1.09 0.39
178 INT345322 Regulation of Transcription of ABCA1 1 0.01 0 0.39
179 INT344684 Positive_regulation of Gene_expression of Abcg1 1 0.10 0.95 0.38
180 INT167122 Protein_catabolism of ABCA1 3 0.02 0.27 0.37
181 INT190598 Localization of Nr1h2 3 0.25 1.6 0.36
182 INT240914 Negative_regulation of Sirt1 9 0.46 3.16 0.34
183 INT146107 Positive_regulation of Lrp1 4 0.37 1.91 0.34
184 INT300466 Phosphorylation of Nr1h2 1 0.21 0.36 0.34
185 INT131542 Negative_regulation of Gene_expression of APOE 6 0.40 3.92 0.33
186 INT198889 Protein_catabolism of Lrp1 5 0.68 1.6 0.32
187 INT179491 Transcription of Adipoq 4 0.51 0.98 0.32
188 INT239295 Positive_regulation of Abca1 3 0.30 2.18 0.32
189 INT335077 Regulation of Nr1h3 1 0.44 0.1 0.32
190 INT253096 Negative_regulation of Positive_regulation of Nr1h2 1 0.16 0.59 0.32
191 INT335072 Regulation of Regulation of Nr1h3 1 0.44 0.1 0.32
192 INT289546 Negative_regulation of Gene_expression of Sirt1 5 0.42 3.1 0.31
193 INT312778 Positive_regulation of Gene_expression of Pon1 1 0.67 2.37 0.31
194 INT132627 Binding of Nfkbia 1 0.03 0.41 0.31
195 INT342668 Regulation of LRP1 1 0.01 0.2 0.31
196 INT204368 Gene_expression of SIRT1 17 0.76 4.48 0.3
197 INT127984 Positive_regulation of LRP1 5 0.69 0.74 0.3
198 INT227268 Negative_regulation of Transcription of Adipoq 4 0.52 4.93 0.3
199 INT311128 Positive_regulation of Regulation of Apoe 1 0.30 0.3 0.3
200 INT175687 Transcription of Apoe 4 0.72 2.12 0.29
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