GO:0010893

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Name positive regulation of steroid biosynthetic process
Categary Process
Go Slim No
Go Link GO:0010893
Unique Molecular Interactions 125
Total Molecular Interactions 158
Total Single Events 1047
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of steroid biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of steroid biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
2 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
3 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
4 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
5 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2
6 INT8409 IL1A Positive_regulation of Positive_regulation of Vip 1 0.01 0.63 1.27
7 INT8410 IL1A Positive_regulation of Vip 1 0.02 0.68 1.05
8 INT292530 Il10 Negative_regulation of Localization of Il1a 1 0.06 1.09 0.97
9 INT159111 Il1a Regulation of Gene_expression of Il1b 1 0.49 0.38 0.97
10 INT216736 Binding of ADORA2B and ATP6V0A1 2 0.08 0.06 0.93
11 INT66536 Il1a Regulation of Gene_expression of Fos 1 0.59 0 0.91
12 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
13 INT21944 Il1a Negative_regulation of Gnrh1 1 0.34 0 0.89
14 INT194856 Positive_regulation of Adora2b Negative_regulation of Positive_regulation of Mmp13 1 0.01 0.73 0.85
15 INT252455 Binding of Adora2b and SLURP1 1 0.02 0.6 0.81
16 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
17 INT196575 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1a 1 0.04 0.44 0.77
18 INT200097 Negative_regulation of Binding of Il1a and Jun 1 0.00 2.76 0.77
19 INT200093 Binding of Il1a and Jun 1 0.00 2.64 0.76
20 INT5971 Il1a Positive_regulation of Crh 2 0.51 0.57 0.71
21 INT250871 Il1a Positive_regulation of Protein_catabolism of Ecm1 1 0.01 1.44 0.68
22 INT95431 Il1a Regulation of Mmp2 1 0.48 0.25 0.61
23 INT306264 Binding of IL1A and MTX1 1 0.09 0.74 0.61
24 INT95435 Il1a Positive_regulation of Positive_regulation of Mmp3 1 0.59 0.25 0.61
25 INT95436 Il1a Positive_regulation of Mmp3 1 0.59 0.25 0.61
26 INT95434 Mmp9 Positive_regulation of Positive_regulation of Il1a 1 0.42 0.23 0.61
27 INT95432 Il1a Positive_regulation of Positive_regulation of Mmp9 1 0.37 0.25 0.6
28 INT222554 Il1a Positive_regulation of Localization of Ngf 1 0.02 0.07 0.6
29 INT8401 Il1a Regulation of Gene_expression of Nts 1 0.00 0.38 0.56
30 INT8395 Il1a Regulation of Gene_expression of Vip 1 0.01 0.38 0.56
31 INT8396 Il1a Regulation of Nts 1 0.00 0.38 0.53
32 INT8399 Il1a Regulation of Vip 1 0.00 0.38 0.53
33 INT129911 Skiv2l Negative_regulation of Localization of IL1A 1 0.01 0.74 0.48
34 INT130723 Binding of IL1A and Il1rn 1 0.01 0.59 0.47
35 INT130724 Negative_regulation of Binding of IL1A and Il1rn 1 0.01 0.59 0.47
36 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47
37 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46
38 INT264473 Il1a Positive_regulation of Mapk1 1 0.00 0 0.43
39 INT264476 Il1a Positive_regulation of Gene_expression of Mapk8 1 0.04 0 0.43
40 INT264471 Il1a Positive_regulation of Gene_expression of Mapk1 1 0.01 0 0.43
41 INT264475 Il1a Positive_regulation of Mapk8 1 0.04 0 0.43
42 INT264479 Il1a Positive_regulation of Gene_expression of Mapk14 1 0.02 0 0.43
43 INT159438 seb Positive_regulation of Gene_expression of Il1a 1 0.02 0 0.41
44 INT159439 sea Positive_regulation of Gene_expression of Il1a 1 0.07 0 0.41
45 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39
46 INT200096 Negative_regulation of Il1a Negative_regulation of Gene_expression of Ptgs2 1 0.00 1.45 0.39
47 INT216737 Binding of ADORA2B and TCFL5 1 0.03 0.05 0.39
48 INT264482 Il1a Positive_regulation of Phosphorylation of Mapk14 1 0.02 0 0.37
49 INT264481 Il1a Positive_regulation of Mapk14 1 0.02 0 0.37
50 INT264480 Il1a Positive_regulation of Phosphorylation of Mapk8 1 0.04 0 0.37
51 INT21945 Negative_regulation of Il1a Negative_regulation of LH 1 0.18 0 0.36
52 INT19476 Binding of IL1A and Il6 1 0.00 2.19 0.36
53 INT19477 Binding of IL1A and Csf2 1 0.00 2.19 0.36
54 INT21946 Il1a Negative_regulation of LH 1 0.18 0 0.35
55 INT242363 Binding of Il1a and Il1rn 1 0.05 0.19 0.35
56 INT254123 Binding of Adora2b and Rai1 1 0.24 0.75 0.35
57 INT252453 Binding of AR and Adora2b 1 0.05 0 0.35
58 INT164904 Binding of IL1A and IL33 1 0.39 0.19 0.35
59 INT113476 IL1A Positive_regulation of Localization of MMP14 1 0.10 0.22 0.34
60 INT97357 IL1A Positive_regulation of Transcription of Timp1 1 0.06 0.47 0.34
61 INT92870 SON Regulation of IL1A 1 0.01 0.31 0.32
62 INT78063 Il1a Positive_regulation of Il1b 1 0.02 0.07 0.32
63 INT203089 Binding of Il1a and Traf6 1 0.04 0.66 0.32
64 INT203085 Positive_regulation of Binding of Il1a and Myd88 1 0.07 0.65 0.32
65 INT203086 Positive_regulation of Binding of Il1a and Traf6 1 0.06 0.67 0.32
66 INT21947 Il1a Positive_regulation of Localization of Pomc 1 0.48 0 0.32
67 INT203087 Binding of Il1a and Myd88 1 0.05 0.65 0.31
68 INT97358 IL1A Regulation of Timp1 1 0.04 0.51 0.31
69 INT102872 IL1A Negative_regulation of Transcription of IL6 1 0.43 0.42 0.31
70 INT241739 Sdhb Regulation of Adora2b 1 0.04 0.63 0.31
71 INT229600 Tlr4 Positive_regulation of Il1a 1 0.00 0.41 0.3
72 INT50310 Binding of Il1a and Ptger2 1 0.20 0.06 0.28
73 INT188518 Il1a Negative_regulation of Gene_expression of Ptger2 1 0.00 0.17 0.28
74 INT188517 Il1a Negative_regulation of Gene_expression of Ptges 1 0.00 0.17 0.28
75 INT188524 Il1a Positive_regulation of Ptges 1 0.00 0.31 0.28
76 INT220381 Il1a Positive_regulation of Gene_expression of Igfbp1 1 0.01 0.28 0.27
77 INT71309 Il1a Positive_regulation of Nos2 1 0.21 0.26 0.26
78 INT80288 IL1A Positive_regulation of CCL13 1 0.17 0.39 0.24
79 INT80280 IL1A Positive_regulation of CCL7 1 0.19 0.39 0.24
80 INT80284 IL1A Positive_regulation of Gene_expression of CCL13 1 0.58 0.39 0.24
81 INT252456 IGKV2D-29 Regulation of Gene_expression of Adora2b 1 0.07 0 0.24
82 INT224135 Binding of ARRB2 and Adora2b 1 0.14 0.07 0.23
83 INT209856 IL1A Negative_regulation of Transcription of CD36 1 0.26 0.1 0.22
84 INT224133 Negative_regulation of Adora2b Positive_regulation of ADCY1 1 0.01 0.1 0.2
85 INT264477 Il1a Positive_regulation of Jun 1 0.02 0.17 0.2
86 INT264470 Il1a Positive_regulation of Il6 1 0.06 0.18 0.2
87 INT102870 PTGER2 Regulation of IL1A 1 0.11 0.28 0.2
88 INT102868 TNF Regulation of IL1A 1 0.27 0.28 0.2
89 INT224134 Adora2b Positive_regulation of ADCY1 1 0.01 0.1 0.2
90 INT226542 Negative_regulation of Adora2b Positive_regulation of IL19 1 0.08 0.58 0.2
91 INT226525 Adora2b Positive_regulation of IL19 1 0.03 0.58 0.2
92 INT102873 IL1A Regulation of Gene_expression of IL6 1 0.27 0.28 0.2
93 INT222543 Il1a Regulation of Chat 1 0.01 0.64 0.19
94 INT222525 Il1a Regulation of Localization of Gh1 1 0.00 0.64 0.19
95 INT222494 Negative_regulation of Il1a Negative_regulation of Positive_regulation of Il6 1 0.00 0.79 0.19
96 INT203088 Il1a Positive_regulation of Gene_expression of Mmp3 1 0.03 0.26 0.18
97 INT66035 FOLR2 Negative_regulation of Il1a 1 0.00 0.56 0.18
98 INT190381 IL1A Regulation of Transcription of DEFB4A 1 0.06 0.93 0.18
99 INT164894 Binding of IL1A and IL1RAP 1 0.08 0.1 0.18
100 INT214380 Binding of IL1A and PRTN3 1 0.00 0.94 0.18
101 INT252454 Negative_regulation of Binding of Adora2b and SLURP1 1 0.02 0.33 0.16
102 INT224136 ARRB2 Positive_regulation of Adora2b 1 0.19 0 0.16
103 INT224132 ARRB2 Negative_regulation of Positive_regulation of Adora2b 1 0.14 0.28 0.15
104 INT221352 Tnf Negative_regulation of Il1a 1 0.05 0.3 0.15
105 INT81992 IL1A Positive_regulation of Positive_regulation of Tnfsf11 1 0.05 0.27 0.13
106 INT81983 IL1A Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.27 0.13
107 INT340421 Il1a Positive_regulation of Csk 1 0.00 0.98 0.12
108 INT71310 Il1a Positive_regulation of NOS1 1 0.07 0.09 0.11
109 INT71311 Il1a Positive_regulation of Positive_regulation of NOS1 1 0.07 0.09 0.11
110 INT294438 KLK4 Negative_regulation of IL1A 1 0.00 0 0.1
111 INT128696 Il1a Positive_regulation of Phosphorylation of Ephb1 1 0.26 0.82 0.1
112 INT190382 IL1A Regulation of Regulation of DEFB4A 1 0.06 0.57 0.1
113 INT16444 IGHG3 Negative_regulation of Binding of IL1A 1 0.11 0.42 0.09
114 INT222511 Il1a Positive_regulation of Gene_expression of Fst 1 0.01 0.32 0.08
115 INT241741 Sdhb Positive_regulation of Transcription of Adora2b 1 0.07 0.28 0.08
116 INT222662 Il1a Positive_regulation of Gene_expression of INCENP 1 0.00 0.32 0.08
117 INT188519 Il1a Positive_regulation of Ptgis 1 0.03 0.08 0.08
118 INT16442 Binding of IGHG3 and IL1A 1 0.10 0.36 0.05
119 INT188525 Il1a Regulation of Ptges 1 0.00 0.07 0.04
120 INT203094 Il1a Positive_regulation of Gene_expression of B4GALNT1 1 0.00 0.05 0.03
121 INT90283 Binding of APOE and Il1a 1 0.01 0 0
122 INT152401 Binding of Il1a and Il23r 1 0.00 0.06 0
123 INT152402 Binding of Il1a and ERAP1 1 0.00 0.06 0
124 INT66034 FOLR2 Negative_regulation of Gene_expression of Il1a 1 0.00 0.18 0
125 INT327809 Binding of ADORA2B and IL8 1 0.03 0.3 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of steroid biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of steroid biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
2 INT5966 Localization of Il1a 50 0.78 22.91 26.54
3 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54
4 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19
5 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24
6 INT125947 Gene_expression of Adora2b 57 0.75 23.69 17
7 INT216751 Gene_expression of ADORA2B 36 0.60 3.42 15.6
8 INT194850 Positive_regulation of Adora2b 43 0.61 20.57 13.89
9 INT60461 Positive_regulation of Gene_expression of Il1a 40 0.61 17.23 12.35
10 INT19527 Negative_regulation of Gene_expression of Il1a 26 0.51 15.4 11.58
11 INT15768 Gene_expression of Il1a 20 0.71 9.31 8.78
12 INT19475 Positive_regulation of IL1A 20 0.67 17.99 7.57
13 INT216752 Binding of ADORA2B 17 0.36 0.76 7.36
14 INT5308 Regulation of Il1a 17 0.44 10.8 7.31
15 INT72532 Regulation of Gene_expression of Il1a 13 0.54 4.91 6.71
16 INT23034 Positive_regulation of Il1a 15 0.70 8.75 6.29
17 INT58468 Negative_regulation of Gene_expression of IL1A 10 0.58 9.39 5.57
18 INT58338 Negative_regulation of Localization of Il1a 8 0.25 3.13 5.18
19 INT69310 Negative_regulation of IL1A 10 0.43 7.83 5.05
20 INT216840 Binding of Adora2b 3 0.47 5.23 4.85
21 INT50309 Binding of Il1a 22 0.40 5.4 4.49
22 INT59083 Positive_regulation of Gene_expression of IL1A 11 0.70 9.09 4.48
23 INT23035 Regulation of Il1a 6 0.60 5.69 4.25
24 INT15462 Negative_regulation of Il1a 4 0.59 4.68 4.17
25 INT19189 Localization of IL1A 14 0.78 9.02 3.78
26 INT224046 Negative_regulation of Adora2b 9 0.43 4 3.6
27 INT54619 Negative_regulation of Positive_regulation of Il1a 6 0.42 5.68 3.12
28 INT16447 Binding of IL1A 10 0.45 4.01 2.78
29 INT49984 Localization of Il1a 5 0.77 3.61 2.42
30 INT5968 Positive_regulation of Localization of Il1a 4 0.65 1.36 2.42
31 INT150884 Transcription of Il1a 6 0.47 3.12 2.19
32 INT224047 Regulation of Adora2b 7 0.27 3.23 2.12
33 INT49988 Positive_regulation of Gene_expression of Il1a 2 0.47 1.49 2.11
34 INT216839 Positive_regulation of Positive_regulation of Adora2b 5 0.45 2.27 2
35 INT89926 Regulation of IL1A 10 0.60 7.12 1.72
36 INT216749 Positive_regulation of ADORA2B 6 0.37 0.89 1.72
37 INT224049 Transcription of Adora2b 6 0.69 5.12 1.67
38 INT216847 Transcription of ADORA2B 1 0.51 0.93 1.55
39 INT49987 Transcription of Il1a 1 0.68 0.66 1.4
40 INT129253 Positive_regulation of Positive_regulation of Il1a 5 0.49 2.97 1.31
41 INT162757 Regulation of Localization of Il1a 3 0.37 1.22 1.25
42 INT59082 Regulation of Gene_expression of IL1A 3 0.45 2.07 1.2
43 INT241724 Localization of Adora2b 2 0.75 1.21 1.14
44 INT224042 Phosphorylation of Adora2b 1 0.29 0.25 1.08
45 INT53571 Negative_regulation of Localization of Il1a 2 0.50 1.59 0.99
46 INT190077 Regulation of Transcription of Il1a 2 0.02 0.87 0.99
47 INT16446 Transcription of IL1A 4 0.69 1.76 0.96
48 INT217050 Positive_regulation of Gene_expression of Adora2b 3 0.50 1.19 0.92
49 INT344365 Phosphorylation of Il1a 1 0.61 1.01 0.92
50 INT83454 Positive_regulation of Negative_regulation of IL1A 1 0.50 0.62 0.81
51 INT23033 Negative_regulation of Positive_regulation of Il1a 2 0.42 0.76 0.78
52 INT194851 Protein_catabolism of Adora2b 1 0.17 0.6 0.75
53 INT241715 Negative_regulation of Gene_expression of Adora2b 2 0.43 0.48 0.73
54 INT53576 Regulation of Gene_expression of Il1a 2 0.41 0.6 0.73
55 INT83453 Negative_regulation of Localization of IL1A 1 0.43 0.39 0.69
56 INT292526 Negative_regulation of Negative_regulation of Il1a 1 0.05 0.87 0.66
57 INT89812 Negative_regulation of Gene_expression of Il1a 1 0.24 0.58 0.66
58 INT252430 Negative_regulation of Binding of Adora2b 1 0.26 0.27 0.65
59 INT216750 Positive_regulation of Gene_expression of ADORA2B 1 0.34 0 0.64
60 INT216761 Positive_regulation of Binding of ADORA2B 1 0.34 0 0.63
61 INT224056 Regulation of Gene_expression of Adora2b 2 0.27 0.12 0.59
62 INT89813 Positive_regulation of Localization of Il1a 1 0.28 0.47 0.55
63 INT216757 Protein_catabolism of ADORA2B 1 0.67 0 0.5
64 INT250838 Protein_catabolism of Il1a 1 0.13 1.16 0.49
65 INT216753 Regulation of Binding of ADORA2B 1 0.18 0 0.48
66 INT250843 Negative_regulation of Protein_catabolism of Il1a 1 0.06 0.9 0.43
67 INT216855 Negative_regulation of ADORA2B 1 0.32 0.05 0.43
68 INT292528 Regulation of Positive_regulation of Il1a 1 0.06 0.52 0.39
69 INT252432 Positive_regulation of Localization of Adora2b 1 0.30 0.06 0.37
70 INT252431 Negative_regulation of Positive_regulation of Adora2b 1 0.26 0.76 0.35
71 INT82758 Positive_regulation of Positive_regulation of IL1A 1 0.45 1.06 0.27
72 INT159502 Positive_regulation of Transcription of IL1A 1 0.45 0.35 0.25
73 INT159501 Regulation of Transcription of IL1A 1 0.44 0.35 0.25
74 INT90281 Binding of Il1a 1 0.01 0.51 0.21
75 INT60460 Positive_regulation of Negative_regulation of Il1a 1 0.36 0 0.18
76 INT224051 Regulation of Phosphorylation of Adora2b 1 0.09 0.09 0.18
77 INT224055 Negative_regulation of Phosphorylation of Adora2b 1 0.15 0 0.16
78 INT224054 Positive_regulation of Phosphorylation of Adora2b 1 0.17 0 0.16
79 INT250827 Positive_regulation of Protein_catabolism of Il1a 1 0.07 0.21 0.09
80 INT252433 Regulation of Positive_regulation of Adora2b 1 0.44 0 0.09
81 INT16448 Negative_regulation of Binding of IL1A 1 0.40 0.41 0.08
82 INT241716 Positive_regulation of Transcription of Adora2b 1 0.50 0.28 0.06
83 INT188502 Positive_regulation of Binding of Il1a 2 0.07 0 0.04
84 INT327819 Localization of ADORA2B 1 0.22 0.3 0
85 INT203070 Regulation of Negative_regulation of Il1a 1 0.14 0 0
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