GO:0010923

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Name negative regulation of phosphatase activity
Categary Process
Go Slim No
Go Link GO:0010923
Unique Molecular Interactions 34
Total Molecular Interactions 54
Total Single Events 179
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of phosphatase activity. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of phosphatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
2 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
3 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
4 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
5 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
6 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
7 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
8 INT112107 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2a 1 0.40 0.49 0.57
9 INT120870 Binding of Wnk1 and Sptlc1 1 0.14 1.24 0.56
10 INT112106 Negative_regulation of Dlg2 Negative_regulation of Grin2a 1 0.40 0.48 0.56
11 INT251143 Binding of Grin2b and Dlg3 1 0.22 0.32 0.55
12 INT251151 Binding of Grin2a and Dlg3 1 0.24 0.32 0.54
13 INT251148 Negative_regulation of Binding of Grin2a and Dlg2 1 0.37 0.45 0.32
14 INT135425 Binding of Dlg4 and Dlg3 1 0.29 0.07 0.28
15 INT157211 Binding of AGXT and WNK1 1 0.07 0.68 0.22
16 INT157212 Binding of SPTLC1 and WNK1 1 0.07 0.67 0.22
17 INT157216 Binding of SPTLC2 and WNK1 1 0.03 0.68 0.22
18 INT337260 ELL Positive_regulation of Gene_expression of THBS1 1 0.11 0.82 0.18
19 INT337263 ELL Regulation of Gene_expression of THBS1 1 0.10 0.82 0.18
20 INT153620 Binding of Ntrk1 and WNK1 1 0.02 0.85 0.12
21 INT230245 Binding of CBFA2T2 and Cd2bp2 1 0.00 0.36 0.08
22 INT295130 Igf1 Regulation of Grxcr1 1 0.02 0.64 0.06
23 INT295122 Bmp2 Regulation of Grxcr1 1 0.02 0.66 0.06
24 INT270659 Wnk1 Regulation of Napg 1 0.04 1.12 0.04
25 INT284097 Binding of MAP4 and WNK1 1 0.39 0.82 0.04
26 INT270661 Regulation of Wnk1 Regulation of Napg 1 0.04 1.13 0.04
27 INT295121 Proc Regulation of Grxcr1 1 0.00 1.26 0.03
28 INT263791 Binding of DLG3 and Dlg4 1 0.20 0 0
29 INT356252 Binding of CLTC and Dlg3 1 0.00 0 0
30 INT263789 Binding of DLG3 and Neto1 1 0.40 0 0
31 INT295124 Binding of Pou1f1 and Grxcr1 1 0.04 0.28 0
32 INT208139 Binding of PITX1 and URI1 1 0.01 0.62 0
33 INT266834 Pth Negative_regulation of Positive_regulation of Grxcr1 1 0.04 0.51 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of phosphatase activity. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of phosphatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT112099 Negative_regulation of Dlg2 2 0.40 6.17 8.16
2 INT112101 Gene_expression of Dlg2 9 0.73 5.06 6.5
3 INT251134 Binding of Dlg2 6 0.31 4.26 5.99
4 INT251126 Regulation of Dlg2 1 0.40 1.56 2.46
5 INT251127 Regulation of Gene_expression of Dlg2 1 0.35 1.49 2.23
6 INT251128 Regulation of Negative_regulation of Dlg2 1 0.24 1.97 2.01
7 INT139546 Gene_expression of URI1 3 0.75 3 1.49
8 INT77246 Positive_regulation of WNK1 5 0.10 4.24 1.13
9 INT247615 Binding of URI1 2 0.20 1.17 1.13
10 INT38625 Gene_expression of ELL 8 0.58 12.53 1
11 INT135422 Binding of Dlg3 3 0.35 0.48 0.88
12 INT8159 Binding of ELL 7 0.36 12.62 0.84
13 INT77247 Binding of WNK1 5 0.46 3.45 0.7
14 INT62688 Binding of Wnk1 2 0.17 2.83 0.63
15 INT143398 Regulation of ELL 2 0.44 2.17 0.59
16 INT249457 Positive_regulation of URI1 3 0.27 0.8 0.45
17 INT90168 Regulation of Wnk1 2 0.04 0.63 0.29
18 INT157219 Gene_expression of WNK1 4 0.58 2.5 0.28
19 INT135423 Gene_expression of Dlg3 1 0.56 0.08 0.28
20 INT319268 Positive_regulation of Dlg2 1 0.16 0.42 0.28
21 INT266832 Positive_regulation of Grxcr1 9 0.12 7.91 0.19
22 INT315759 Regulation of URI1 1 0.01 0.12 0.19
23 INT266822 Negative_regulation of Grxcr1 10 0.10 8.12 0.17
24 INT301343 Negative_regulation of Positive_regulation of ELL 1 0.08 1.64 0.17
25 INT238096 Positive_regulation of ELL 4 0.09 2.68 0.16
26 INT167957 Gene_expression of Grxcr1 8 0.10 3.43 0.14
27 INT230237 Binding of Cd2bp2 1 0.01 0.36 0.08
28 INT131835 Positive_regulation of Wnk1 1 0.07 1.28 0.07
29 INT293405 Transcription of URI1 1 0.03 0.74 0.07
30 INT266821 Positive_regulation of Negative_regulation of Grxcr1 1 0.06 1.51 0.06
31 INT266820 Positive_regulation of Positive_regulation of Grxcr1 1 0.06 1.58 0.06
32 INT346683 Protein_catabolism of URI1 1 0.19 0.15 0.05
33 INT212930 Localization of ELL 2 0.15 0.87 0.04
34 INT295107 Negative_regulation of Gene_expression of Grxcr1 1 0.04 0.49 0.04
35 INT266823 Regulation of Grxcr1 3 0.06 1.4 0.03
36 INT250504 Negative_regulation of URI1 1 0.10 0.71 0.03
37 INT266818 Localization of Grxcr1 7 0.12 3.9 0
38 INT230372 Negative_regulation of ELL 5 0.03 1.35 0
39 INT266819 Regulation of Localization of Grxcr1 2 0.06 1.28 0
40 INT302374 Binding of DLG3 1 0.04 1.08 0
41 INT263712 Transcription of DLG3 1 0.67 0.07 0
42 INT144997 Negative_regulation of Wnk1 1 0.08 0 0
43 INT179648 Localization of WNK1 1 0.38 0.92 0
44 INT309294 Negative_regulation of Gene_expression of WNK1 1 0.04 0 0
45 INT345669 Regulation of Gene_expression of WNK1 1 0.01 0.15 0
46 INT295108 Positive_regulation of Gene_expression of Grxcr1 1 0.07 0.52 0
47 INT295083 Positive_regulation of Localization of Grxcr1 1 0.05 0.49 0
48 INT295094 Regulation of Gene_expression of Grxcr1 1 0.04 0.07 0
49 INT346682 Positive_regulation of Gene_expression of URI1 1 0.14 0.27 0
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