GO:0010944

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Name negative regulation of transcription by competitive promoter binding
Categary Process
Go Slim No
Go Link GO:0010944
Unique Molecular Interactions 321
Total Molecular Interactions 418
Total Single Events 4104
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of transcription by competitive promoter binding. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of transcription by competitive promoter binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
2 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
3 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
4 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
5 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
6 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
7 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
8 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
9 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
10 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
11 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
12 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
13 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
14 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
15 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
16 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
17 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
18 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
19 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
20 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
21 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
22 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
23 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
24 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23
25 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
26 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
27 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
28 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
29 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
30 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
31 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
32 INT119888 Binding of Creb1 and Usf1 1 0.18 0.15 1.05
33 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
34 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
35 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
36 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
37 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9
38 INT309140 Dlat Positive_regulation of Creb1 1 0.06 1.1 0.9
39 INT142128 Nrgn Regulation of Creb1 1 0.38 0.25 0.89
40 INT73653 Binding of Creb1 and Fos 1 0.40 1.49 0.87
41 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84
42 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81
43 INT109142 Calca Positive_regulation of Transcription of Creb1 1 0.47 0.13 0.8
44 INT182839 Camk4 Positive_regulation of Creb1 3 0.49 1.81 0.79
45 INT114924 Creb1 Regulation of Positive_regulation of Oprm1 1 0.09 0.13 0.79
46 INT186439 Prkaca Regulation of Phosphorylation of Creb1 1 0.06 0.08 0.79
47 INT131194 Creb1 Positive_regulation of Gene_expression of Pdyn 1 0.26 0.08 0.79
48 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79
49 INT172982 Binding of MUC1 and MUC4 1 0.30 2.46 0.78
50 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
51 INT261413 Positive_regulation of GRIN1 Positive_regulation of Positive_regulation of Creb1 1 0.00 0.81 0.77
52 INT106335 Olr1254 Positive_regulation of Phosphorylation of Creb1 1 0.03 0 0.76
53 INT109141 Calca Positive_regulation of Creb1 1 0.47 0.13 0.76
54 INT109143 Calca Positive_regulation of Phosphorylation of Creb1 1 0.47 0.13 0.76
55 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
56 INT186445 Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
57 INT186443 Phosphorylation of Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
58 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
59 INT186444 Creb1 Regulation of FOS 1 0.49 0.43 0.72
60 INT253828 Creb1 Positive_regulation of Gene_expression of Cartpt 1 0.19 0.15 0.72
61 INT186442 Phosphorylation of Creb1 Regulation of FOS 1 0.49 0.43 0.72
62 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
63 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
64 INT123300 Mks1 Positive_regulation of Creb1 1 0.01 0.35 0.7
65 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
66 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
67 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
68 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
69 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
70 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
71 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
72 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
73 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66
74 INT266064 Binding of PAG1 and Creb1 1 0.04 1.52 0.65
75 INT266049 Binding of Ceacam3 and Creb1 1 0.14 1.53 0.65
76 INT132154 PSG7 Positive_regulation of Localization of MUC1 1 0.00 0 0.65
77 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64
78 INT266047 Creb1 Regulation of Ceacam3 1 0.20 1.15 0.62
79 INT186429 Camk2a Regulation of Regulation of Creb1 1 0.09 0.09 0.62
80 INT121873 Creb1 Regulation of Phosphorylation of Car2 1 0.10 0 0.62
81 INT123301 Car2 Positive_regulation of Creb1 1 0.21 0.28 0.61
82 INT113962 OPRM1 Regulation of CREB1 1 0.39 0.31 0.6
83 INT98725 Msr1 Positive_regulation of Gene_expression of Creb1 1 0.00 0.09 0.6
84 INT186434 Trib3 Positive_regulation of Phosphorylation of Creb1 1 0.05 0.26 0.58
85 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
86 INT317637 Ngf Regulation of Creb1 1 0.10 0.11 0.57
87 INT92974 Creb1 Regulation of Positive_regulation of Galr1 1 0.32 0 0.57
88 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57
89 INT305732 Tst Positive_regulation of Creb1 1 0.12 0.33 0.57
90 INT73656 Creb1 Positive_regulation of Transcription of Pdyn 1 0.42 0.97 0.56
91 INT296169 Binding of Htr4 and Creb1 1 0.49 0.1 0.56
92 INT296293 Prkaca Regulation of Positive_regulation of Creb1 1 0.16 0.62 0.55
93 INT105424 Creb1 Positive_regulation of Gene_expression of Penk 1 0.49 0 0.55
94 INT114928 Positive_regulation of Creb1 Positive_regulation of Positive_regulation of Oprm1 1 0.16 0.05 0.54
95 INT305738 Binding of Creb1 and Atf6b 1 0.08 0.34 0.53
96 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
97 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
98 INT219038 Creb1 Regulation of Gene_expression of Bdnf 1 0.25 0.25 0.49
99 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
100 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
101 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
102 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
103 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48
104 INT305735 Binding of Bdnf and Creb1 1 0.08 0.49 0.47
105 INT305746 Positive_regulation of Creb1 Positive_regulation of BDNF 1 0.32 0.41 0.47
106 INT305743 Binding of Bdnf and Positive_regulation of Positive_regulation of Creb1 1 0.11 0.49 0.47
107 INT235882 Creb1 Positive_regulation of Positive_regulation of Bdnf 1 0.11 0.17 0.47
108 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46
109 INT305736 Positive_regulation of Creb1 Positive_regulation of Bdnf 1 0.10 0.41 0.46
110 INT317640 Slc3a1 Positive_regulation of Creb1 1 0.12 0.58 0.46
111 INT161162 Creb1 Regulation of Nts 1 0.19 0.15 0.45
112 INT259208 Ca2 Positive_regulation of Phosphorylation of Creb1 1 0.04 0 0.45
113 INT317636 Creb1 Positive_regulation of Phosphorylation of Hmmr 1 0.04 0.55 0.45
114 INT283731 Trib3 Positive_regulation of Creb1 2 0.01 0.16 0.44
115 INT151782 Phosphorylation of Creb1 Positive_regulation of Gene_expression of P2rx1 1 0.41 0.07 0.44
116 INT309113 Edc4 Positive_regulation of Gene_expression of Creb1 1 0.03 0.45 0.43
117 INT106333 Olr1254 Positive_regulation of Creb1 1 0.02 0 0.43
118 INT309145 Positive_regulation of Edc4 Positive_regulation of Creb1 1 0.02 0.35 0.42
119 INT186148 Camk4 Positive_regulation of Phosphorylation of Creb1 2 0.50 1.11 0.4
120 INT235868 Creb1 Negative_regulation of Atf6b 1 0.02 0.21 0.4
121 INT302825 Binding of Creb1 and Xpnpep1 1 0.00 0.64 0.39
122 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
123 INT354820 Creb1 Negative_regulation of Transcription of Cpox 1 0.03 0.59 0.38
124 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
125 INT207211 Binding of Creb1 and Crem 2 0.30 1.35 0.36
126 INT340607 Bdnf Regulation of Gene_expression of Creb1 1 0.36 0.31 0.36
127 INT274937 Ephb2 Regulation of Phosphorylation of Creb1 1 0.21 0 0.36
128 INT132174 PSG7 Positive_regulation of Gene_expression of Muc1 1 0.00 0 0.34
129 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
130 INT132169 PSG7 Positive_regulation of Muc1 1 0.00 0 0.34
131 INT273955 Creb1 Positive_regulation of Transcription of Crh 1 0.14 0.96 0.33
132 INT207212 Creb1 Regulation of Bdnf 1 0.17 0.92 0.32
133 INT126851 Prkcg Positive_regulation of Creb1 1 0.46 0.09 0.32
134 INT132155 PSG7 Positive_regulation of Gene_expression of MUC1 1 0.00 0 0.32
135 INT182837 Binding of Creb1 and Crebbp 1 0.12 0.57 0.32
136 INT126852 Prkaca Positive_regulation of Creb1 1 0.27 0.09 0.32
137 INT124258 Creb1 Regulation of Gene_expression of Cpox 1 0.17 0.44 0.32
138 INT186430 Creb1 Positive_regulation of Trib3 1 0.04 0.17 0.3
139 INT118655 Bdnf Positive_regulation of Phosphorylation of Creb1 1 0.44 0.16 0.3
140 INT118653 Binding of Bdnf and Creb1 1 0.39 0.19 0.3
141 INT186152 Camk4 Regulation of Phosphorylation of Creb1 3 0.27 0.44 0.29
142 INT190826 ELANE Positive_regulation of Localization of MUC1 1 0.07 0 0.29
143 INT73657 Binding of Jun and Creb1 1 0.25 0.5 0.29
144 INT286699 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.22 0.18 0.28
145 INT296284 Calm3 Regulation of Positive_regulation of Creb1 1 0.09 0.31 0.28
146 INT286704 Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.32 0.18 0.28
147 INT179425 Fig4 Regulation of Creb1 1 0.02 0.32 0.28
148 INT286701 Rps6ka5 Positive_regulation of Phosphorylation of Creb1 1 0.20 0.18 0.28
149 INT283732 Prkaca Positive_regulation of Creb1 1 0.03 0 0.28
150 INT283733 Trib3 Positive_regulation of Creb1 1 0.00 0 0.28
151 INT51858 Akr1d1 Positive_regulation of Phosphorylation of Creb1 1 0.01 0 0.27
152 INT296287 Camk4 Regulation of Positive_regulation of Creb1 1 0.27 0.31 0.27
153 INT186151 Camk4 Regulation of Creb1 2 0.27 1.06 0.25
154 INT194670 CREB1 Regulation of Gene_expression of CD4 1 0.05 0.07 0.25
155 INT194714 CREB1 Regulation of Gene_expression of IK 1 0.00 0.07 0.25
156 INT169049 Positive_regulation of Binding of Creb1 and Sult4a1 1 0.47 0.11 0.24
157 INT169051 Binding of Creb1 and Sult4a1 1 0.32 0.11 0.24
158 INT95741 Creb1 Regulation of Mapk8 1 0.39 0 0.23
159 INT147590 Binding of Muc1 and Mag 1 0.26 3.29 0.23
160 INT255842 CREB1 Regulation of Binding of ATF2 1 0.03 0.12 0.22
161 INT255837 ATF2 Regulation of Binding of CREB1 1 0.03 0.12 0.22
162 INT190827 KCNA1 Regulation of Localization of MUC1 1 0.05 0.08 0.22
163 INT255940 Elk1 Regulation of Transcription of CREB1 1 0.03 0.12 0.22
164 INT255835 ATF2 Regulation of Transcription of CREB1 1 0.03 0.12 0.22
165 INT150582 Creb1 Positive_regulation of Gene_expression of Homer1 1 0.00 0 0.22
166 INT255839 CREB1 Regulation of Transcription of ATF2 1 0.03 0.12 0.22
167 INT255947 CREB1 Regulation of Transcription of Elk1 1 0.03 0.12 0.22
168 INT255943 Elk1 Regulation of Binding of CREB1 1 0.03 0.12 0.22
169 INT255938 CREB1 Regulation of Binding of Elk1 1 0.03 0.12 0.22
170 INT87169 Creb1 Positive_regulation of Gene_expression of Nkx1-1 1 0.11 0.17 0.21
171 INT137228 MAPK1 Positive_regulation of Phosphorylation of Creb1 1 0.46 0 0.2
172 INT257233 PRKG1 Positive_regulation of Phosphorylation of Creb1 1 0.01 0.09 0.2
173 INT257224 Pde5a Positive_regulation of Phosphorylation of Creb1 1 0.03 0.09 0.2
174 INT57383 Binding of Creb1 and Penk 1 0.05 0.67 0.2
175 INT99797 Jun Positive_regulation of Creb1 1 0.15 0.19 0.2
176 INT308669 CREB1 Regulation of Gene_expression of Ins1 1 0.01 0 0.19
177 INT308657 Creb1 Regulation of Gene_expression of Ins1 1 0.01 0 0.19
178 INT182929 Binding of CREB1 and KCNIP3 1 0.18 0.37 0.19
179 INT320260 Binding of Atf4 and Creb1 1 0.15 0.36 0.17
180 INT114936 Myoz1 Positive_regulation of Creb1 1 0.00 0 0.17
181 INT156970 Negative_regulation of Kcnip3 Positive_regulation of Transcription of Creb1 1 0.47 0.45 0.17
182 INT318188 MUC5AC Positive_regulation of MUC1 1 0.16 1.12 0.17
183 INT320257 Binding of Atf3 and Creb1 1 0.15 0.36 0.17
184 INT156971 Kcnip3 Negative_regulation of Creb1 1 0.48 0.46 0.17
185 INT194838 Binding of CREB1 and Nfatc1 1 0.01 0.07 0.16
186 INT194826 Binding of CREB1 and Crebbp 1 0.02 0.07 0.16
187 INT244116 ELAVL3 Negative_regulation of MUC1 1 0.09 3.41 0.15
188 INT103889 Pdyn Regulation of Gene_expression of Creb1 1 0.03 0.19 0.15
189 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
190 INT117912 CREB1 Positive_regulation of Positive_regulation of MAPK1 1 0.04 0.89 0.13
191 INT185455 MUC1 Negative_regulation of Timp1 1 0.06 0.84 0.13
192 INT138195 Binding of HDAC4 and Creb1 1 0.03 0.17 0.13
193 INT182958 Binding of CA2 and CREB1 1 0.04 0.25 0.13
194 INT309130 Edc4 Regulation of Creb1 1 0.02 0.12 0.13
195 INT280819 Binding of Creb1 and gr 1 0.01 0 0.13
196 INT201749 Creb1 Positive_regulation of Ngf 1 0.03 0.33 0.13
197 INT185416 MUC1 Negative_regulation of TIMP1 1 0.18 0.84 0.13
198 INT287878 Binding of CREB1 and CREBBP 2 0.01 0.16 0.12
199 INT54544 CREB1 Regulation of PENK 1 0.59 0 0.12
200 INT54545 Binding of CREB1 and PENK 1 0.35 0 0.12

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of transcription by competitive promoter binding. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of transcription by competitive promoter binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
2 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
3 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
4 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
5 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26
6 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77
7 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39
8 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
9 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
10 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
11 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25
12 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
13 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64
14 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19
15 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28
16 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
17 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
18 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52
19 INT62577 Negative_regulation of Creb1 55 0.59 19.68 18.1
20 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06
21 INT102023 Regulation of Creb1 51 0.62 16.29 16.71
22 INT107248 Negative_regulation of Gene_expression of Creb1 26 0.58 9.24 13.41
23 INT16713 Binding of Creb1 53 0.48 20.24 13.06
24 INT62576 Transcription of Creb1 34 0.69 16.97 10.6
25 INT109280 Negative_regulation of Phosphorylation of Creb1 29 0.59 11.81 10.37
26 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18
27 INT109279 Regulation of Phosphorylation of Creb1 14 0.62 4.06 8.96
28 INT49802 Localization of MUC1 75 0.81 44.74 8.87
29 INT93673 Transcription of Creb1 19 0.66 9.27 8.26
30 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91
31 INT116619 Positive_regulation of Positive_regulation of Creb1 25 0.69 8.32 7.3
32 INT86867 Regulation of CREB1 15 0.46 4.95 7.28
33 INT106330 Regulation of Positive_regulation of Creb1 11 0.56 5.57 7.06
34 INT114642 Negative_regulation of Positive_regulation of Creb1 12 0.57 2.32 6.75
35 INT92971 Binding of Creb1 31 0.47 11.3 6.22
36 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84
37 INT61986 Localization of Creb1 16 0.69 2.12 5.66
38 INT102019 Regulation of Gene_expression of Creb1 14 0.61 5.27 5.08
39 INT102202 Negative_regulation of Positive_regulation of Creb1 11 0.58 4.55 4.99
40 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56
41 INT121866 Localization of Creb1 13 0.73 1.95 4.48
42 INT84809 Positive_regulation of Gene_expression of MUC1 39 0.70 36.42 3.75
43 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69
44 INT11015 Regulation of Phosphorylation of CREB1 4 0.46 1.45 3.17
45 INT111554 Positive_regulation of Regulation of Creb1 4 0.50 2.12 2.85
46 INT156021 Positive_regulation of Transcription of Creb1 8 0.57 3.36 2.83
47 INT98919 Negative_regulation of Phosphorylation of CREB1 8 0.58 2.4 2.63
48 INT158666 Regulation of Transcription of Creb1 6 0.45 2.41 2.44
49 INT9473 Binding of MUC1 66 0.48 46.77 2.36
50 INT173005 Transcription of MUC1 11 0.63 10.15 2.24
51 INT87168 Positive_regulation of Binding of Creb1 4 0.48 4.6 2.21
52 INT159118 Protein_catabolism of Creb1 3 0.61 0.37 2.17
53 INT106718 Regulation of Positive_regulation of Creb1 9 0.45 3.7 2.16
54 INT49803 Negative_regulation of MUC1 37 0.58 26.37 2.06
55 INT174924 Gene_expression of Smad7 6 0.41 3.59 1.76
56 INT174923 Positive_regulation of Gene_expression of Smad7 3 0.37 2.3 1.73
57 INT69917 Negative_regulation of CREB1 8 0.58 2.28 1.59
58 INT132163 Positive_regulation of Localization of MUC1 9 0.19 8.96 1.54
59 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
60 INT98923 Negative_regulation of Localization of Creb1 3 0.50 0.66 1.26
61 INT120076 Positive_regulation of Gene_expression of Smad7 16 0.65 11.33 1.25
62 INT169721 Negative_regulation of Negative_regulation of Creb1 1 0.43 0.09 1.22
63 INT121867 Positive_regulation of Localization of Creb1 2 0.60 0.43 1.2
64 INT49804 Negative_regulation of Localization of MUC1 7 0.59 5.84 1.19
65 INT142831 Positive_regulation of Gene_expression of CREB1 3 0.69 0.08 1.1
66 INT207201 Positive_regulation of Transcription of Creb1 4 0.50 0.69 1.09
67 INT71476 Negative_regulation of Regulation of Creb1 1 0.18 0.17 1.06
68 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
69 INT142829 Transcription of CREB1 9 0.46 3.37 1.03
70 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
71 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
72 INT115494 Negative_regulation of Positive_regulation of CREB1 2 0.05 1.25 0.83
73 INT89290 Regulation of MUC1 19 0.45 10.4 0.81
74 INT149817 Gene_expression of Bhlhe41 2 0.43 2.47 0.81
75 INT173003 Negative_regulation of Gene_expression of MUC1 15 0.57 10.27 0.79
76 INT282916 Positive_regulation of Transcription of MUC1 2 0.45 0.47 0.79
77 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
78 INT54546 Binding of CREB1 9 0.41 3.44 0.72
79 INT272878 Negative_regulation of Smad7 4 0.41 3.86 0.72
80 INT114536 Regulation of Negative_regulation of Creb1 1 0.45 0 0.72
81 INT149819 Regulation of Gene_expression of Bhlhe41 1 0.29 0 0.7
82 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
83 INT149804 Regulation of Bhlhe41 1 0.29 0 0.69
84 INT132164 Gene_expression of Muc1 4 0.71 4.15 0.67
85 INT271162 Positive_regulation of Regulation of Creb1 1 0.20 0.3 0.67
86 INT121868 Regulation of Localization of Creb1 1 0.23 0 0.66
87 INT93674 Regulation of Binding of Creb1 1 0.38 0.1 0.62
88 INT142827 Regulation of Gene_expression of CREB1 3 0.61 0.39 0.61
89 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
90 INT80300 Gene_expression of TFAP2A 5 0.54 2.76 0.59
91 INT303595 Negative_regulation of Localization of Creb1 1 0.19 0.86 0.57
92 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
93 INT343798 Negative_regulation of Transcription of MUC1 1 0.39 0.37 0.5
94 INT120074 Regulation of Gene_expression of Smad7 1 0.58 2.05 0.5
95 INT207194 Regulation of Regulation of Creb1 2 0.45 1.09 0.46
96 INT317620 Negative_regulation of Binding of Creb1 1 0.40 0.81 0.46
97 INT116134 Positive_regulation of Positive_regulation of CREB1 2 0.28 0.59 0.45
98 INT142828 Regulation of Transcription of CREB1 1 0.24 0 0.45
99 INT173022 Regulation of Gene_expression of MUC1 9 0.60 7.59 0.44
100 INT224538 Negative_regulation of Gene_expression of Smad7 1 0.09 0.25 0.43
101 INT124256 Positive_regulation of Binding of Creb1 2 0.40 1.27 0.39
102 INT274924 Positive_regulation of Protein_catabolism of Creb1 1 0.30 0 0.39
103 INT80302 Binding of TFAP2A 7 0.39 1.67 0.38
104 INT106402 Positive_regulation of TFAP2A 2 0.13 0.35 0.35
105 INT173635 Negative_regulation of TFAP2A 3 0.34 2.93 0.33
106 INT124253 Negative_regulation of Binding of Creb1 3 0.42 0.75 0.32
107 INT134840 Gene_expression of SMAD7 1 0.74 2.74 0.31
108 INT184716 Binding of Smad7 2 0.34 0.91 0.29
109 INT272890 Regulation of Negative_regulation of Smad7 1 0.19 1.33 0.29
110 INT292207 Negative_regulation of Gene_expression of TFAP2A 1 0.05 1.2 0.27
111 INT229206 Regulation of Positive_regulation of CREB1 2 0.11 0.25 0.25
112 INT228793 Negative_regulation of Gene_expression of Smad7 5 0.25 2.33 0.23
113 INT147586 Positive_regulation of Gene_expression of Muc1 1 0.43 2.54 0.22
114 INT348361 Localization of Muc1 1 0.27 0.58 0.2
115 INT162939 Binding of Tfap2a 1 0.26 0.34 0.17
116 INT162940 Negative_regulation of Tfap2a 1 0.32 0.34 0.17
117 INT162941 Negative_regulation of Binding of Tfap2a 1 0.32 0.34 0.17
118 INT266053 Positive_regulation of Protein_catabolism of Creb1 1 0.50 0.96 0.17
119 INT273921 Regulation of Binding of Creb1 2 0.35 0.28 0.16
120 INT266056 Protein_catabolism of Creb1 1 0.88 0.95 0.16
121 INT228790 Positive_regulation of Smad7 4 0.41 0.58 0.15
122 INT338872 Regulation of Regulation of Creb1 1 0.21 0.28 0.15
123 INT176329 Protein_catabolism of MUC1 4 0.72 2.14 0.14
124 INT147589 Binding of Muc1 1 0.41 2.48 0.13
125 INT266058 Regulation of Localization of Creb1 1 0.39 0.38 0.11
126 INT207192 Negative_regulation of Transcription of Creb1 1 0.43 0.58 0.11
127 INT98920 Localization of CREB1 4 0.52 1.77 0.1
128 INT69911 Negative_regulation of Binding of CREB1 1 0.48 0 0.1
129 INT176328 Positive_regulation of Protein_catabolism of MUC1 1 0.41 0.86 0.09
130 INT194802 Negative_regulation of Gene_expression of CREB1 1 0.14 0.07 0.08
131 INT353267 Negative_regulation of Positive_regulation of Smad7 1 0.25 0.32 0.08
132 INT282927 Regulation of Localization of MUC1 1 0.26 0.92 0.07
133 INT129204 Positive_regulation of Positive_regulation of MUC1 2 0.09 1.01 0.06
134 INT97754 Regulation of Gene_expression of TFAP2A 1 0.36 0.13 0.06
135 INT147587 Negative_regulation of Muc1 1 0.50 0.88 0.06
136 INT347149 Localization of Smad7 1 0.67 0 0.05
137 INT180026 Positive_regulation of Bhlhe41 1 0.35 0.79 0.05
138 INT221856 Regulation of Positive_regulation of MUC1 1 0.25 0.85 0.04
139 INT350515 Transcription of SMAD7 1 0.07 0.38 0.03
140 INT353280 Phosphorylation of Smad7 1 0.48 0.06 0.03
141 INT282929 Negative_regulation of Binding of MUC1 1 0.57 0.34 0
142 INT139622 Transcription of Muc1 1 0.21 0 0
143 INT347148 Regulation of Smad7 1 0.26 0 0
144 INT173648 Regulation of Binding of TFAP2A 1 0.03 0.32 0
145 INT282917 Negative_regulation of Protein_catabolism of MUC1 1 0.37 0.22 0
146 INT139621 Regulation of Gene_expression of Muc1 1 0.56 0 0
147 INT218701 Negative_regulation of Binding of Smad7 1 0.14 0.15 0
148 INT173631 Negative_regulation of Positive_regulation of TFAP2A 1 0.05 0.27 0
149 INT243078 Gene_expression of Phb 1 0.42 0.09 0
150 INT166121 Binding of SMAD7 1 0.30 0.39 0
151 INT282924 Regulation of Transcription of MUC1 1 0.26 0.12 0
152 INT353273 Negative_regulation of Phosphorylation of Smad7 1 0.25 0 0
153 INT173627 Negative_regulation of Binding of TFAP2A 1 0.08 0.28 0
154 INT347145 Transcription of Smad7 1 0.68 0 0
155 INT173642 Transcription of TFAP2A 1 0.09 0.27 0
156 INT271772 Negative_regulation of Positive_regulation of MUC1 1 0.08 0 0
157 INT282920 Positive_regulation of Negative_regulation of MUC1 1 0.45 0.11 0
158 INT282915 Positive_regulation of Binding of MUC1 1 0.49 0.45 0
159 INT282926 Phosphorylation of MUC1 1 0.79 0.06 0
160 INT218685 Binding of Smad7 1 0.13 0.15 0
161 INT173645 Regulation of TFAP2A 1 0.02 0.33 0
162 INT173630 Positive_regulation of Transcription of TFAP2A 1 0.06 0.54 0
163 INT311630 Negative_regulation of Tfap2a 1 0.34 0.23 0
164 INT319128 Positive_regulation of Binding of Tfap2a 1 0.23 0.5 0
165 INT311626 Negative_regulation of Gene_expression of Tfap2a 1 0.34 0.29 0
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