GO:0010980

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Name positive regulation of vitamin D 24-hydroxylase activity
Categary Process
Go Slim No
Go Link GO:0010980
Unique Molecular Interactions 82
Total Molecular Interactions 119
Total Single Events 715
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of vitamin D 24-hydroxylase activity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of vitamin D 24-hydroxylase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT37840 Binding of Cyp27b1 and Oprd1 1 0.01 0 1.73
2 INT37839 Positive_regulation of Binding of Cyp27b1 and Oprd1 1 0.01 0 0.86
3 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
4 INT171990 Binding of DMD and VDR 5 0.05 2.58 0.39
5 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29
6 INT137683 Positive_regulation of Binding of Cyp27b1 and Prkca 1 0.03 0 0.29
7 INT137684 Binding of Cyp27b1 and Prkca 1 0.02 0 0.29
8 INT330976 Igh-Dex Positive_regulation of Gene_expression of VDR 1 0.01 1.11 0.23
9 INT262151 Vdr Regulation of Cyp24a1 1 0.24 0.24 0.23
10 INT335021 Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.53 1.49 0.21
11 INT335020 Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.62 0.82 0.18
12 INT197647 DPH1 Negative_regulation of VDR 1 0.02 0.58 0.18
13 INT335018 Vdr Positive_regulation of Gene_expression of Fgf23 1 0.44 0.36 0.17
14 INT335026 Positive_regulation of Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.45 0.2 0.13
15 INT335024 Positive_regulation of Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.39 0.19 0.13
16 INT333765 Positive_regulation of Vdr Regulation of Gene_expression of Ccr6 1 0.21 0.48 0.12
17 INT166723 Binding of Vdr and Rxrb 1 0.11 0.31 0.09
18 INT267156 Binding of VDR and SUGT1 1 0.04 3.4 0.09
19 INT166724 Binding of Vdr and Rxra 1 0.28 0.32 0.09
20 INT330955 HOMER1 Positive_regulation of Gene_expression of VDR 1 0.01 0.99 0.08
21 INT262216 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Vdr 1 0.29 0.44 0.08
22 INT197649 NR1I2 Positive_regulation of VDR 1 0.15 0.54 0.07
23 INT197648 ESRRB Positive_regulation of VDR 1 0.03 0.54 0.07
24 INT218009 AHR Positive_regulation of CYP27B1 1 0.16 0.06 0.05
25 INT339272 VDR Positive_regulation of Gene_expression of KRT20 1 0.00 0.07 0.05
26 INT182936 HGFAC Positive_regulation of VDR 1 0.00 0.06 0.05
27 INT182914 KCNIP3 Positive_regulation of VDR 1 0.40 0.06 0.05
28 INT218010 EE Positive_regulation of CYP27B1 1 0.05 0 0.04
29 INT285388 Ahr Positive_regulation of Gene_expression of Cyp27b1 1 0.01 0.14 0.04
30 INT262196 Nr1i2 Negative_regulation of Vdr 1 0.27 0.14 0.04
31 INT335017 Fgf23 Positive_regulation of Fgfr1 1 0.23 0.59 0.04
32 INT218011 AHR Positive_regulation of Transcription of CYP27B1 1 0.16 0 0.04
33 INT262166 Binding of Nr1i2 and Vdr 1 0.23 0.14 0.04
34 INT285386 Ahr Positive_regulation of Binding of Cyp27b1 1 0.01 0.14 0.04
35 INT262154 Vdr Negative_regulation of Cyp24a1 1 0.16 0.14 0.04
36 INT335016 Fgf23 Negative_regulation of Gene_expression of Slc34a3 1 0.03 0.63 0.03
37 INT297375 Binding of VDR and Rxra 1 0.02 0.2 0.03
38 INT316598 Pth Regulation of Fgf23 1 0.10 0.28 0.03
39 INT264382 NR1H4 Positive_regulation of VDR 1 0.04 0.09 0.03
40 INT182950 Binding of VDR and NR1H4 5 0.03 1.16 0
41 INT182949 Binding of RARA and VDR 1 0.20 0 0
42 INT182942 VDR Positive_regulation of CDKN1A 1 0.35 0.38 0
43 INT342385 Positive_regulation of Binding of Lrp5 and Vdr 1 0.53 0.98 0
44 INT330958 Binding of VDR and BTG2 1 0.07 0.51 0
45 INT342378 Binding of Vdr and Best1 1 0.05 0.4 0
46 INT354923 Binding of VDR and Uvbs1 1 0.00 0.83 0
47 INT183016 Binding of VDR and Dre 1 0.01 0.12 0
48 INT44023 Binding of Cyp27b1 and Klk1b27 1 0.00 0.1 0
49 INT342265 Binding of VDR and HHIP 1 0.00 0.93 0
50 INT182955 Positive_regulation of Binding of VDR and NR1H4 1 0.03 0 0
51 INT182940 Binding of VDR and TNFRSF25 1 0.22 0.21 0
52 INT245733 Binding of VDR and DISC1 1 0.03 0.75 0
53 INT182926 VDR Positive_regulation of HNF4A 1 0.02 0.09 0
54 INT44025 Binding of Cd86 and Cyp27b1 1 0.02 0.1 0
55 INT338190 Binding of PCa and VDR 1 0.00 0.84 0
56 INT342381 Binding of Lrp5 and Vdr 1 0.55 0.97 0
57 INT266837 Dmp1 Negative_regulation of Gene_expression of Fgf23 1 0.48 2.41 0
58 INT342388 Binding of CALCR and Vdr 1 0.12 0.83 0
59 INT182939 Binding of DR1 and VDR 1 0.12 0 0
60 INT182920 Binding of PDYN and VDR 1 0.12 0.07 0
61 INT330959 Binding of RXRB and VDR 1 0.05 0.14 0
62 INT182953 Binding of VDR and KCNIP3 1 0.24 0.1 0
63 INT182959 Binding of VDR and TNFRSF10B 1 0.16 0 0
64 INT225578 Binding of Vdr and Pprc1 1 0.00 0 0
65 INT182962 TGFBI Regulation of VDR 1 0.42 0.08 0
66 INT330957 Binding of TEP1 and VDR 1 0.01 1.07 0
67 INT291711 Rxra Positive_regulation of VDR 1 0.09 0 0
68 INT182917 Binding of VDR and Positive_regulation of Gene_expression of CDKN1A 1 0.35 0.31 0
69 INT266839 Fgf23 Negative_regulation of Slc34a1 1 0.21 0.88 0
70 INT335019 Fgf23 Positive_regulation of Phosphorylation of Mapk1 1 0.08 0.45 0
71 INT266833 Phex Regulation of Gene_expression of Fgf23 1 0.23 0.46 0
72 INT182928 VDR Regulation of PDYN 1 0.09 0.07 0
73 INT182931 VDR Positive_regulation of Gene_expression of CDKN1A 1 0.48 0.86 0
74 INT266838 Fgf23 Regulation of Slc34a1 1 0.13 0.3 0
75 INT197643 TNF Regulation of VDR 1 0.04 1.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of vitamin D 24-hydroxylase activity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of vitamin D 24-hydroxylase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT119700 Gene_expression of VDR 88 0.75 65.33 11.5
2 INT123701 Negative_regulation of VDR 61 0.59 48.94 9.67
3 INT156850 Binding of VDR 40 0.47 24.86 4.87
4 INT39908 Gene_expression of Cyp27b1 16 0.69 4.8 2.83
5 INT160633 Gene_expression of Vdr 21 0.77 10.01 2.73
6 INT102638 Regulation of VDR 21 0.44 9.92 2.54
7 INT102639 Positive_regulation of VDR 31 0.69 18.05 2.38
8 INT61225 Positive_regulation of Cyp27b1 8 0.31 2.32 2.24
9 INT29577 Negative_regulation of Cyp27b1 5 0.37 2.41 1.88
10 INT37838 Regulation of Cyp27b1 4 0.27 0.67 1.61
11 INT112214 Gene_expression of Vdr 4 0.33 3.59 1.11
12 INT118373 Gene_expression of Fgf23 16 0.77 29.62 1.04
13 INT182968 Positive_regulation of Gene_expression of VDR 22 0.58 15.22 0.89
14 INT71197 Positive_regulation of Gene_expression of Cyp27b1 3 0.20 0.49 0.89
15 INT118371 Positive_regulation of Fgf23 15 0.69 25.34 0.85
16 INT71194 Transcription of Cyp27b1 4 0.15 0.99 0.84
17 INT130797 Gene_expression of Fgf23 6 0.66 4.73 0.77
18 INT262107 Binding of Vdr 9 0.48 6.56 0.71
19 INT183009 Phosphorylation of VDR 3 0.68 1 0.68
20 INT262060 Positive_regulation of Vdr 8 0.58 2.84 0.67
21 INT287118 Negative_regulation of Gene_expression of VDR 3 0.36 3.53 0.66
22 INT35705 Regulation of CYP27B1 1 0.23 0 0.66
23 INT177337 Localization of VDR 6 0.73 3.44 0.59
24 INT44016 Binding of Cyp27b1 3 0.10 0.53 0.59
25 INT124270 Positive_regulation of Gene_expression of Vdr 2 0.29 1.1 0.58
26 INT71187 Positive_regulation of Transcription of Cyp27b1 1 0.13 0.2 0.51
27 INT71196 Positive_regulation of Binding of Cyp27b1 1 0.13 0.19 0.51
28 INT119708 Transcription of VDR 11 0.71 5.43 0.48
29 INT112215 Binding of Vdr 4 0.31 2.43 0.44
30 INT160642 Positive_regulation of Gene_expression of Vdr 5 0.62 1.61 0.42
31 INT88678 Gene_expression of CYP27B1 8 0.75 2.11 0.41
32 INT218020 Positive_regulation of CYP27B1 3 0.49 0.15 0.41
33 INT71190 Regulation of Gene_expression of Cyp27b1 1 0.13 0.17 0.39
34 INT71191 Regulation of Positive_regulation of Cyp27b1 1 0.13 0.17 0.39
35 INT262063 Localization of Vdr 3 0.75 1.76 0.33
36 INT137677 Positive_regulation of Positive_regulation of Cyp27b1 2 0.07 0.56 0.32
37 INT135880 Positive_regulation of Gene_expression of Fgf23 4 0.46 7.52 0.29
38 INT130799 Localization of Fgf23 2 0.63 1.94 0.28
39 INT157409 Negative_regulation of Fgf23 3 0.50 3.21 0.27
40 INT145009 Positive_regulation of Negative_regulation of VDR 2 0.41 1.18 0.25
41 INT102637 Positive_regulation of Vdr 3 0.48 2.82 0.24
42 INT218021 Positive_regulation of Gene_expression of CYP27B1 2 0.67 0.73 0.21
43 INT262040 Negative_regulation of Gene_expression of Vdr 1 0.25 0.26 0.21
44 INT130798 Positive_regulation of Gene_expression of Fgf23 2 0.59 1.12 0.2
45 INT137674 Localization of Cyp27b1 1 0.10 0 0.2
46 INT160641 Transcription of Vdr 5 0.71 3.1 0.16
47 INT118372 Regulation of Fgf23 4 0.55 3.31 0.15
48 INT227044 Negative_regulation of Gene_expression of Cyp27b1 2 0.06 0.46 0.15
49 INT149951 Negative_regulation of Transcription of VDR 3 0.43 1.19 0.13
50 INT333738 Regulation of Positive_regulation of Vdr 1 0.38 0.48 0.12
51 INT88677 Negative_regulation of Gene_expression of CYP27B1 2 0.57 0.91 0.11
52 INT137680 Regulation of Localization of Cyp27b1 1 0.07 0 0.11
53 INT295974 Regulation of Fgf23 1 0.07 2.3 0.11
54 INT178814 Regulation of Binding of VDR 2 0.38 0.57 0.08
55 INT88676 Negative_regulation of CYP27B1 2 0.30 1.96 0.07
56 INT266826 Binding of Fgf23 1 0.32 1.26 0.07
57 INT211082 Regulation of Positive_regulation of Vdr 1 0.30 1.18 0.07
58 INT119703 Regulation of Gene_expression of VDR 4 0.44 2.43 0.06
59 INT211079 Positive_regulation of Positive_regulation of Vdr 1 0.33 0.59 0.05
60 INT218026 Localization of CYP27B1 1 0.73 0.07 0.05
61 INT266828 Negative_regulation of Fgf23 3 0.42 5.63 0.04
62 INT119704 Transcription of CYP27B1 2 0.69 0.48 0.04
63 INT262079 Negative_regulation of Vdr 2 0.42 0.71 0.04
64 INT218025 Positive_regulation of Transcription of CYP27B1 1 0.49 0 0.04
65 INT316595 Transcription of Fgf23 1 0.61 0.44 0.04
66 INT339273 Negative_regulation of Binding of VDR 1 0.21 0.07 0.04
67 INT354920 Negative_regulation of Positive_regulation of VDR 1 0.21 1.96 0.04
68 INT211080 Negative_regulation of Positive_regulation of Vdr 1 0.29 0.6 0.04
69 INT316589 Negative_regulation of Transcription of Fgf23 1 0.50 0.44 0.04
70 INT335007 Protein_catabolism of Fgf23 1 0.59 1.28 0.03
71 INT316588 Positive_regulation of Fgf23 1 0.43 0.29 0.03
72 INT354921 Positive_regulation of Localization of VDR 1 0.23 0.79 0.03
73 INT119701 Regulation of Transcription of VDR 2 0.61 0.57 0
74 INT150308 Protein_catabolism of Fgf23 1 0.75 0.05 0
75 INT182982 Positive_regulation of Phosphorylation of VDR 1 0.42 0 0
76 INT288196 Negative_regulation of Transcription of Vdr 1 0.23 0 0
77 INT306016 Positive_regulation of Positive_regulation of VDR 1 0.20 1.26 0
78 INT334982 Phosphorylation of Fgf23 1 0.73 1.21 0
79 INT297368 Regulation of Positive_regulation of VDR 1 0.27 1.66 0
80 INT335003 Negative_regulation of Localization of Fgf23 1 0.39 2.37 0
81 INT334997 Localization of Fgf23 1 0.72 3.56 0
82 INT266824 Regulation of Positive_regulation of Fgf23 1 0.27 1.22 0
83 INT140704 Transcription of Vdr 1 0.12 0.38 0
84 INT322591 Regulation of Negative_regulation of VDR 1 0.16 1.29 0
85 INT171996 Regulation of Regulation of VDR 1 0.44 0.05 0
86 INT334991 Positive_regulation of Positive_regulation of Fgf23 1 0.39 1.5 0
87 INT150307 Positive_regulation of Protein_catabolism of Fgf23 1 0.52 0.11 0
88 INT342376 Positive_regulation of Binding of Vdr 1 0.46 0.86 0
89 INT266825 Positive_regulation of Regulation of Fgf23 1 0.46 0.25 0
90 INT334993 Negative_regulation of Gene_expression of Fgf23 1 0.38 4.1 0
91 INT160644 Positive_regulation of Transcription of Vdr 1 0.62 0 0
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