GO:0010989

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Name negative regulation of low-density lipoprotein particle clearance
Categary Process
Go Slim No
Go Link GO:0010989
Unique Molecular Interactions 24
Total Molecular Interactions 30
Total Single Events 100
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of low-density lipoprotein particle clearance. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of low-density lipoprotein particle clearance. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT118001 Csk Regulation of Trpv1 1 0.08 0.09 0.58
2 INT118002 Binding of Trpv1 and Csk 1 0.06 0.08 0.38
3 INT297335 Binding of Apoc3 and Hdl1 1 0.00 0.92 0.29
4 INT329850 APOA5 Negative_regulation of Transcription of APOC3 1 0.24 0.85 0.15
5 INT148800 VEGFA Positive_regulation of Positive_regulation of Csk 1 0.06 0 0.14
6 INT148802 Negative_regulation of VEGFA Positive_regulation of Csk 1 0.05 0 0.14
7 INT148801 VEGFA Positive_regulation of Csk 1 0.06 0 0.14
8 INT340421 Il1a Positive_regulation of Csk 1 0.00 0.98 0.12
9 INT208353 Binding of Apoc4 and Apoc3 1 0.00 2.56 0.04
10 INT325027 Apoc3 Negative_regulation of Pnlip 1 0.01 1.02 0.04
11 INT325026 Apoc3 Negative_regulation of Lpl 1 0.03 1.01 0.04
12 INT332978 ACOX1 Negative_regulation of Transcription of Apoc3 1 0.00 0.98 0
13 INT247441 Binding of APOC3 and SNRNP70 1 0.04 0.26 0
14 INT247444 Binding of APOA1 and APOC3 1 0.28 0.39 0
15 INT208349 Regulation of Binding of Apoc3 and Apoe 1 0.01 0.38 0
16 INT171599 Binding of APOC3 and Sst1 1 0.01 0.68 0
17 INT208365 Apoc3 Positive_regulation of Localization of PROC 1 0.00 1.13 0
18 INT332962 Acaa1a Negative_regulation of Transcription of Apoc3 1 0.01 0.93 0
19 INT208355 Binding of Apoc3 and Apoe 1 0.01 0.76 0
20 INT286444 PCSK9 Positive_regulation of Apob 1 0.02 0.49 0
21 INT300199 PCSK9 Regulation of Gene_expression of LDLR 1 0.13 0.88 0
22 INT171602 APOC3 Negative_regulation of Lipg 1 0.04 0.38 0
23 INT149996 Npy6r Negative_regulation of Csk 1 0.01 0 0
24 INT171603 APOC3 Negative_regulation of Lpl 1 0.48 0.38 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of low-density lipoprotein particle clearance. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of low-density lipoprotein particle clearance. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT190883 Gene_expression of Apoc3 16 0.38 14.18 1.93
2 INT148788 Binding of Csk 2 0.12 2.14 1.89
3 INT132837 Positive_regulation of Csk 5 0.45 1.75 1.79
4 INT148937 Positive_regulation of Csk 2 0.13 2.25 1.63
5 INT132835 Phosphorylation of Csk 2 0.36 0 0.83
6 INT148786 Negative_regulation of Csk 4 0.09 0.97 0.62
7 INT132836 Regulation of Csk 1 0.30 0.42 0.59
8 INT130791 Regulation of Csk 1 0.07 0.86 0.54
9 INT322158 Phosphorylation of Csk 2 0.10 1.49 0.52
10 INT335112 Regulation of Localization of APOC3 1 0.13 0.73 0.4
11 INT335117 Localization of APOC3 1 0.40 0.73 0.4
12 INT190878 Positive_regulation of Gene_expression of Apoc3 3 0.29 2.76 0.3
13 INT126864 Negative_regulation of Csk 1 0.12 0.58 0.3
14 INT228468 Localization of Csk 1 0.12 0.79 0.29
15 INT228467 Positive_regulation of Gene_expression of Csk 1 0.08 0.79 0.29
16 INT228473 Positive_regulation of Localization of Csk 1 0.08 0.79 0.29
17 INT228471 Gene_expression of Csk 1 0.11 0.79 0.29
18 INT171597 Gene_expression of APOC3 9 0.77 3.18 0.2
19 INT335113 Negative_regulation of Gene_expression of APOC3 1 0.24 0.34 0.2
20 INT208335 Binding of Apoc3 3 0.01 2.11 0.18
21 INT190876 Negative_regulation of Apoc3 2 0.15 1.43 0.17
22 INT171595 Negative_regulation of APOC3 3 0.43 1.99 0.15
23 INT171589 Transcription of APOC3 2 0.71 1.25 0.15
24 INT148793 Negative_regulation of Positive_regulation of Csk 1 0.06 0 0.14
25 INT190877 Regulation of Gene_expression of Apoc3 2 0.11 2.09 0.13
26 INT148789 Negative_regulation of Binding of Csk 1 0.06 0 0.13
27 INT322280 Binding of PCSK9 1 0.33 0.94 0.12
28 INT208332 Positive_regulation of Apoc3 4 0.29 3.3 0.1
29 INT303073 Positive_regulation of Gene_expression of Csk 1 0.13 0.25 0.04
30 INT303070 Gene_expression of Csk 1 0.14 0.25 0.04
31 INT171594 Binding of APOC3 5 0.37 3.97 0
32 INT171590 Regulation of Gene_expression of APOC3 1 0.61 0.41 0
33 INT332950 Negative_regulation of Transcription of Apoc3 1 0.03 0.92 0
34 INT171592 Positive_regulation of APOC3 1 0.46 0.63 0
35 INT332957 Transcription of Apoc3 1 0.06 0.91 0
36 INT300232 Gene_expression of PCSK9 1 0.57 0.8 0
37 INT286443 Positive_regulation of PCSK9 1 0.16 0.48 0
38 INT332948 Negative_regulation of Gene_expression of Apoc3 1 0.05 0.93 0
39 INT171596 Negative_regulation of Transcription of APOC3 1 0.58 0.42 0
40 INT171593 Positive_regulation of Gene_expression of APOC3 1 0.69 0.55 0
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