GO:0012505

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Name endomembrane system
Categary Component
Go Slim No
Go Link GO:0012505
Unique Molecular Interactions 369
Total Molecular Interactions 499
Total Single Events 4023
Pain Genes Associated 45

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for endomembrane system. They are ordered first by their pain relevance and then by number of times they were reported for endomembrane system. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
2 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
3 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
4 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
5 INT169768 Binding of Slc6a4 and Mir16-1 1 0.33 0 1.25
6 INT105918 Binding of FUT1 and SLC9A3R2 1 0.00 0.14 1.2
7 INT215648 Binding of Adora1 and Gabrd 1 0.03 0.06 1.16
8 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
9 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
10 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02
11 INT203040 Binding of PDCD1 and PDCD1LG2 3 0.40 4.86 0.98
12 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94
13 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
14 INT333303 Zic2 Regulation of Gene_expression of Slc6a4 1 0.60 0.47 0.91
15 INT151630 Il1rn Negative_regulation of Dock9 1 0.03 1.33 0.88
16 INT215646 Binding of Adora1 and P2rx2 1 0.13 0.51 0.85
17 INT308495 Pcsk5 Regulation of CFI 1 0.01 0.22 0.85
18 INT140280 Negative_regulation of Binding of Adora2a and Grina 1 0.21 0.64 0.82
19 INT140281 Binding of Adora2a and Grina 1 0.19 0.64 0.82
20 INT16438 Atp6v0d2 Regulation of Localization of Lnpep 1 0.01 0 0.81
21 INT16435 Ubqln1 Regulation of Localization of Lnpep 1 0.01 0 0.81
22 INT60102 Adora1 Regulation of Localization of Calca 1 0.46 0 0.79
23 INT158684 MAPK8 Positive_regulation of Gene_expression of BCL2L11 1 0.51 0.44 0.78
24 INT72017 Binding of Adora2a and Ptprg 2 0.07 0 0.77
25 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77
26 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
27 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
28 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
29 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76
30 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76
31 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
32 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
33 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
34 INT159687 Trpv4 Negative_regulation of Trpv2 1 0.32 0.41 0.76
35 INT82040 Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.11 0 0.75
36 INT169769 Mir16-1 Regulation of Slc6a4 1 0.24 0 0.74
37 INT333296 Gtf3a Regulation of Gene_expression of Slc6a4 1 0.01 0 0.74
38 INT129557 Binding of Trpv2 and Trpv1 1 0.41 0.18 0.74
39 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
40 INT82041 Positive_regulation of Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.12 0 0.72
41 INT144124 Binding of P2rx6 and Trpv2 1 0.09 0 0.7
42 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69
43 INT203046 Binding of PDCD1 and CD274 2 0.40 3.97 0.68
44 INT141063 Agt Regulation of Agtr1a 1 0.28 1.18 0.68
45 INT74727 Binding of Slc6a4 and Hpic1 1 0.00 0.49 0.68
46 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
47 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68
48 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
49 INT333305 Zic2 Positive_regulation of Transcription of Slc6a4 1 0.68 0 0.66
50 INT259776 Fbn2 Regulation of Negative_regulation of Agtr1a 1 0.00 1.42 0.66
51 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64
52 INT239501 Binding of Adora2a and Mtx1 1 0.24 0.95 0.64
53 INT144107 Binding of SLC6A2 and SLC6A4 1 0.00 0.18 0.62
54 INT259768 Positive_regulation of Agtr1a Regulation of Etf1 1 0.00 1.32 0.62
55 INT215647 Adora1 Positive_regulation of Kcnj5 1 0.00 0 0.62
56 INT37034 PLAT Positive_regulation of PLDN 1 0.08 0.15 0.58
57 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58
58 INT333302 Zic2 Positive_regulation of Slc6a4 1 0.68 0.11 0.57
59 INT203056 Binding of Cd274 and PDCD1LG2 1 0.13 1.61 0.57
60 INT203041 Binding of CD274 and PDCD1LG2 1 0.03 1.61 0.57
61 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55
62 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
63 INT311256 Nt5e Positive_regulation of Positive_regulation of Adora1 1 0.49 0.19 0.54
64 INT156517 Binding of CNR1 and FAAH 3 0.38 1.53 0.53
65 INT128431 SLC6A4 Regulation of S100A4 1 0.48 0.65 0.53
66 INT79809 Binding of Agtr1a and Adra1a 1 0.02 0.23 0.53
67 INT328058 IL4 Positive_regulation of FAAH 1 0.29 4.29 0.53
68 INT47745 Binding of Slc6a4 and Htr2a 1 0.33 0.09 0.52
69 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51
70 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5
71 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
72 INT327806 Binding of ADORA1 and ADORA2A 1 0.06 0.18 0.49
73 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
74 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
75 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47
76 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
77 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
78 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
79 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
80 INT156521 Binding of CNR2 and FAAH 1 0.38 0.19 0.46
81 INT156518 Binding of FAAH and NAPEPLD 1 0.38 0.19 0.46
82 INT113248 Olr1259 Negative_regulation of Slc6a4 1 0.00 0.23 0.44
83 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43
84 INT130975 Binding of ASIC3 and Slc9a3r1 1 0.06 0.26 0.43
85 INT89666 Binding of Adora2a and Drd2 1 0.54 0.4 0.42
86 INT215651 Binding of Adora1 and Cpa1 1 0.00 0 0.42
87 INT273111 Bdnf Positive_regulation of Positive_regulation of Mtor 1 0.44 0.07 0.42
88 INT302871 Negative_regulation of Adora2a Positive_regulation of Phosphorylation of Th 1 0.26 0.12 0.4
89 INT278932 Binding of Agtr1a and H3 1 0.00 0 0.39
90 INT234607 Socs3 Negative_regulation of JAK1 1 0.01 0.54 0.39
91 INT237369 SOAT1 Negative_regulation of Phosphorylation of JAK1 1 0.00 0 0.38
92 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38
93 INT278957 JAK3 Positive_regulation of Gene_expression of IL8 1 0.28 0.67 0.38
94 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
95 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
96 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38
97 INT303994 Il6 Positive_regulation of JAK2 1 0.03 0.41 0.37
98 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
99 INT278955 JAK3 Positive_regulation of Gene_expression of PRKCA 1 0.12 0.65 0.37
100 INT154782 Binding of SLC6A4 and Ndst2 1 0.01 0 0.37
101 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
102 INT278949 JAK3 Positive_regulation of Gene_expression of LEP 1 0.42 0.63 0.36
103 INT130974 Slc9a3r1 Positive_regulation of ASIC3 1 0.08 0.29 0.36
104 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
105 INT239503 Binding of Adora2a and Aes 1 0.24 0.85 0.35
106 INT330122 Agt Positive_regulation of Gene_expression of Agtr1a 1 0.03 0.69 0.34
107 INT115162 Adora2a Regulation of Gene_expression of Jun 1 0.49 0.36 0.34
108 INT140667 IFNG Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
109 INT330121 Agtr1a Positive_regulation of Gene_expression of Bdkrb1 1 0.05 0.68 0.34
110 INT140666 TNF Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
111 INT273118 Bdnf Positive_regulation of Mtor 1 0.66 0 0.33
112 INT115161 Adora2a Regulation of Gene_expression of Cpe 1 0.04 0.36 0.33
113 INT229363 Negative_regulation of Binding of Agt and Agtr1a 2 0.22 0.9 0.32
114 INT235869 Binding of Slc6a4 and Ppp2ca 1 0.04 0.21 0.31
115 INT235877 Prkaca Regulation of Transcription of Slc6a4 1 0.06 0.13 0.31
116 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3
117 INT254122 Adora2a Regulation of Aliq1 1 0.01 0.85 0.3
118 INT341777 SLC6A4 Regulation of EPHB1 1 0.02 0.96 0.3
119 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
120 INT215645 Binding of Adora1 and Kcnj5 1 0.00 0.08 0.29
121 INT235874 Camk2a Positive_regulation of Slc6a4 1 0.11 0.14 0.28
122 INT45544 Ncapg2 Regulation of Localization of Lnpep 1 0.00 0 0.28
123 INT45541 Agt Positive_regulation of Lnpep 1 0.03 0 0.27
124 INT215653 Binding of Adora1 and Adora3 1 0.39 0.07 0.27
125 INT328064 IL10 Positive_regulation of FAAH 1 0.05 1.48 0.26
126 INT88555 Adora2a Negative_regulation of Vegfc 1 0.00 0.17 0.25
127 INT309888 INS Positive_regulation of Gene_expression of FAAH 1 0.04 1.19 0.25
128 INT215652 Binding of Adora1 and Npy1r 1 0.39 0.22 0.24
129 INT160464 Binding of Mme and Lnpep 1 0.31 0.37 0.24
130 INT183247 ADA Negative_regulation of ADORA1 1 0.01 0 0.23
131 INT258398 Binding of IL6R and JAK1 1 0.01 0.75 0.23
132 INT37033 PLAT Negative_regulation of PLDN 1 0.08 0.07 0.23
133 INT343433 Binding of Trpv2 and Trpv1 1 0.36 0.06 0.23
134 INT224130 Positive_regulation of Adora2a Positive_regulation of ADCY1 1 0.01 0.11 0.22
135 INT224087 Adrbk1 Negative_regulation of Adora2a 1 0.10 0.13 0.22
136 INT237748 Negative_regulation of Jak3 Negative_regulation of Positive_regulation of Stat3 1 0.25 1.01 0.22
137 INT297257 Agtr1a Positive_regulation of Agtr2 1 0.27 0.59 0.22
138 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
139 INT328059 IL4 Regulation of FAAH 1 0.25 4.57 0.21
140 INT72015 Binding of Adora2a and Gnai2 1 0.01 0 0.21
141 INT229360 Agt Positive_regulation of Agtr1a 2 0.48 1.26 0.2
142 INT333298 Zic2 Regulation of Transcription of Slc6a4 1 0.44 0.09 0.2
143 INT343436 Binding of Trpv2 and Gpx6 1 0.01 0.13 0.2
144 INT343434 Regulation of Binding of Trpv2 and Gpx6 1 0.01 0.13 0.2
145 INT230749 Crp Regulation of Agtr1a 1 0.07 1.33 0.19
146 INT224086 Binding of Agtr1a and Hspa8 1 0.00 0.1 0.19
147 INT226346 Binding of IL21 and Positive_regulation of Positive_regulation of JAK3 1 0.08 0.48 0.18
148 INT256987 Binding of Cd81 and Slc9a3r1 1 0.43 0.06 0.17
149 INT224094 Adrbk1 Regulation of Negative_regulation of Adora2a 1 0.06 0 0.17
150 INT224126 Binding of Hspa8 and Agtr1a 1 0.00 0.09 0.17
151 INT226339 Binding of IK and JAK1 1 0.00 0.46 0.16
152 INT178269 Slc11a2 Regulation of a 1 0.06 0.97 0.16
153 INT352290 Binding of Agtr1a and P2ry1 1 0.00 0 0.16
154 INT349560 Olr779 Negative_regulation of Mtor 1 0.02 0.5 0.16
155 INT235883 Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
156 INT226366 Binding of CISH and JAK1 1 0.00 0.46 0.15
157 INT147385 Binding of TRPV1 and TRPV2 1 0.37 0 0.15
158 INT235879 Regulation of Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
159 INT147386 Regulation of Binding of TRPV1 and TRPV2 1 0.45 0 0.15
160 INT273902 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.56 0.15
161 INT293124 Agtr1a Regulation of Gene_expression of Aqp2 1 0.17 0.36 0.14
162 INT106994 PARD3 Positive_regulation of PAR4 1 0.21 0.28 0.14
163 INT349559 Mtor Regulation of Pdpk1 1 0.03 0.42 0.14
164 INT249322 Positive_regulation of Adora1 Regulation of Rit2 1 0.10 0 0.14
165 INT293119 Agtr1a Regulation of Positive_regulation of Crh 1 0.12 0.37 0.14
166 INT224129 Binding of DRD2 and Adora2a 1 0.03 0.19 0.14
167 INT273901 Mtor Positive_regulation of Eif4e 1 0.50 0.54 0.14
168 INT144027 Binding of Slc6a4 and Pdgfrb 1 0.23 0.25 0.14
169 INT107006 PARD3 Positive_regulation of SPG21 1 0.24 0.29 0.14
170 INT204159 Slc11a2 Regulation of Gene_expression of HAMP 1 0.11 1.08 0.14
171 INT293123 Agtr1a Regulation of Negative_regulation of Agt 1 0.14 0.25 0.14
172 INT86551 Ppm1f Positive_regulation of Camk1g 1 0.49 0 0.13
173 INT288701 Epas1 Regulation of Transcription of Slc11a2 1 0.29 0.38 0.13
174 INT106997 PARD3 Positive_regulation of NR1I2 1 0.19 0.28 0.13
175 INT328060 LEP Positive_regulation of FAAH 1 0.06 0.7 0.13
176 INT254643 Binding of Mapk8ip1 and Slc9a3r2 1 0.00 0.27 0.12
177 INT110176 Nts Regulation of Negative_regulation of Agtr1a 1 0.24 0.09 0.12
178 INT249321 Positive_regulation of Adora1 Regulation of Preb 1 0.20 0.09 0.12
179 INT229359 Agt Positive_regulation of Binding of Agtr1a 1 0.25 0.9 0.12
180 INT273103 Binding of Mtor and Rps6kb1 1 0.44 0 0.11
181 INT258714 Camk1g Positive_regulation of Gpd1 1 0.46 0.07 0.11
182 INT169340 Binding of UGT8 and Jak2 1 0.36 0.15 0.11
183 INT273112 Positive_regulation of Binding of Mtor and Rps6kb1 1 0.46 0.05 0.11
184 INT313482 Binding of MTOR and SST 1 0.01 0 0.1
185 INT346526 Binding of ADORA1 and PTH1R 1 0.01 0 0.1
186 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
187 INT245951 Binding of FIBP and Phax 1 0.00 0 0.09
188 INT245921 Binding of FIBP and CAP1 1 0.00 0 0.09
189 INT137252 BCL2L11 Regulation of NCAM1 1 0.20 0.99 0.08
190 INT249994 Binding of Agtr1a and Igkv4-55 1 0.01 0.38 0.08
191 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08
192 INT355022 Cntf Positive_regulation of JAK1 1 0.00 0.69 0.08
193 INT249126 Binding of Ephb1 and Mtor 1 0.02 0 0.08
194 INT137254 BCL2L11 Regulation of VIM 1 0.17 0.99 0.08
195 INT137251 BCL2L11 Regulation of CDH1 1 0.17 0.99 0.08
196 INT137255 BCL2L11 Regulation of SLC4A3 1 0.10 0.99 0.08
197 INT273104 Mtor Negative_regulation of Gene_expression of Gria1 1 0.46 0.15 0.08
198 INT249465 Positive_regulation of Slc6a4 Positive_regulation of Gene_expression of Bdnf 1 0.31 0.3 0.08
199 INT137256 BCL2L11 Regulation of SLC4A1 1 0.24 0.99 0.08
200 INT137253 BCL2L11 Regulation of CD99 1 0.23 0.99 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for endomembrane system. They are ordered first by their pain relevance and then by number of times they were reported in endomembrane system. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
2 INT81251 Gene_expression of Trpv2 78 0.78 28.27 41.76
3 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03
4 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23
5 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84
6 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
7 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
8 INT16431 Localization of Lnpep 62 0.70 6.28 23.94
9 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
10 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
11 INT25872 Positive_regulation of Adora1 19 0.69 4.9 15.01
12 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24
13 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78
14 INT79703 Gene_expression of Agtr1a 46 0.76 14.18 13.77
15 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75
16 INT81249 Positive_regulation of Trpv2 21 0.70 8.13 12.36
17 INT100096 Regulation of Slc6a4 24 0.62 7.25 12.28
18 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23
19 INT96406 Regulation of Trpv2 14 0.62 7.45 12.04
20 INT53038 Positive_regulation of Agtr1a 35 0.67 23.76 11.68
21 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47
22 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
23 INT19155 Binding of Adora1 25 0.47 6.41 10.72
24 INT66303 Regulation of Slc6a4 10 0.45 4.82 10.55
25 INT238920 Positive_regulation of SLC9A3R2 44 0.50 27.86 10.51
26 INT10982 Negative_regulation of Agtr1a 42 0.58 22.42 10.29
27 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
28 INT108405 Gene_expression of FAAH 48 0.78 28.22 9.97
29 INT47744 Binding of Slc6a4 21 0.48 5.52 9.45
30 INT133118 Negative_regulation of FAAH 25 0.59 13.05 9.37
31 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
32 INT107898 Gene_expression of Trpv2 27 0.76 10.55 9.28
33 INT114406 Gene_expression of Adora1 28 0.72 6.83 9.13
34 INT23209 Binding of Adora2a 17 0.38 2.04 8.35
35 INT10627 Positive_regulation of Lnpep 24 0.69 3.36 7.85
36 INT9350 Regulation of ADORA1 9 0.12 1.53 7.79
37 INT54755 Negative_regulation of Adora2a 17 0.58 2.7 7.75
38 INT101699 Regulation of Adora1 14 0.61 3.7 7.59
39 INT40159 Negative_regulation of Adora1 13 0.51 3.51 7.13
40 INT119651 Binding of Slc6a4 12 0.32 4.65 7.07
41 INT76197 Positive_regulation of ADORA1 7 0.59 5.06 7
42 INT9167 Binding of Adora1 6 0.40 0.53 6.9
43 INT76255 Gene_expression of ADORA1 11 0.78 2.51 6.85
44 INT15092 Positive_regulation of SLC6A4 17 0.67 7.32 6.7
45 INT109714 Transcription of SLC6A4 7 0.72 3.8 6.19
46 INT93165 Gene_expression of TRPV2 32 0.78 12.49 5.62
47 INT10624 Regulation of Lnpep 13 0.61 3.27 5.6
48 INT83014 Binding of Adora2a 13 0.48 5.57 5.33
49 INT137593 Regulation of Gene_expression of SLC6A4 7 0.60 2.59 5.23
50 INT119711 Positive_regulation of Slc6a4 16 0.69 4.44 5.21
51 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19
52 INT114627 Positive_regulation of Gene_expression of Trpv2 9 0.70 6.41 5.18
53 INT89664 Negative_regulation of Adora2a 11 0.59 7.81 5.07
54 INT16432 Positive_regulation of Localization of Lnpep 12 0.32 1.15 5.05
55 INT23611 Gene_expression of Mtor 23 0.66 3.57 5.02
56 INT105216 Positive_regulation of Trpv2 9 0.61 4.12 4.93
57 INT51468 Regulation of Adora2a 8 0.48 1.5 4.84
58 INT122675 Negative_regulation of Gene_expression of Slc6a4 14 0.59 6.4 4.69
59 INT81250 Transcription of Trpv2 7 0.64 1.54 4.27
60 INT53040 Binding of Agtr1a 22 0.47 7.36 4.15
61 INT79343 Positive_regulation of Slc6a4 10 0.50 1.77 4.05
62 INT50228 Positive_regulation of Positive_regulation of Adora2a 8 0.39 0.1 4
63 INT158573 Negative_regulation of Jak3 3 0.43 8.2 3.99
64 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
65 INT124028 Localization of Trpv2 6 0.80 2.04 3.96
66 INT140670 Negative_regulation of Gene_expression of SLC6A4 4 0.51 2.7 3.88
67 INT103021 Transcription of Slc6a4 16 0.70 3.93 3.77
68 INT65527 Positive_regulation of Positive_regulation of Adora1 4 0.46 0.67 3.71
69 INT101701 Regulation of Adora2a 8 0.45 2.3 3.63
70 INT39786 Transcription of Lnpep 3 0.69 0.52 3.61
71 INT215604 Localization of Adora1 10 0.78 1.47 3.49
72 INT118035 Positive_regulation of JAK1 23 0.67 10.57 3.29
73 INT99291 Transcription of Slc6a4 7 0.46 1.16 3.28
74 INT32340 Negative_regulation of Lnpep 14 0.49 2.63 3.26
75 INT127455 Positive_regulation of Gene_expression of Slc6a4 9 0.59 5.62 3.2
76 INT111195 Negative_regulation of Gene_expression of Agtr1a 7 0.58 3.2 3.16
77 INT100190 Regulation of Gene_expression of Slc6a4 5 0.39 1.8 3.14
78 INT17673 Negative_regulation of Localization of Lnpep 8 0.09 2.63 3.12
79 INT101477 Binding of ADORA1 8 0.31 0.42 3.07
80 INT124438 Regulation of Gene_expression of Slc6a4 9 0.62 3.5 2.97
81 INT54178 Regulation of Adora1 5 0.39 0.29 2.85
82 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83
83 INT12903 Gene_expression of Lnpep 14 0.71 1.3 2.78
84 INT228678 Phosphorylation of Mtor 15 0.78 3.18 2.76
85 INT108403 Protein_catabolism of FAAH 9 0.89 2.5 2.75
86 INT215608 Negative_regulation of Binding of Adora1 5 0.41 1.35 2.73
87 INT215601 Regulation of Positive_regulation of Adora1 9 0.60 1.74 2.66
88 INT80320 Negative_regulation of Gene_expression of Slc6a4 4 0.42 0.85 2.6
89 INT215599 Positive_regulation of Positive_regulation of Adora1 7 0.47 2.29 2.58
90 INT114020 Gene_expression of Adora1 2 0.33 4.24 2.55
91 INT16433 Regulation of Localization of Lnpep 6 0.11 0.32 2.45
92 INT63418 Regulation of Agtr1a 8 0.44 3.67 2.43
93 INT254118 Negative_regulation of Gene_expression of Adora2a 3 0.42 2.54 2.43
94 INT113339 Binding of JAK2 6 0.40 5.31 2.4
95 INT120726 Positive_regulation of Gene_expression of Slc6a4 4 0.68 0.51 2.34
96 INT183167 Positive_regulation of Gene_expression of Adora2a 4 0.70 2.37 2.31
97 INT10626 Regulation of Positive_regulation of Lnpep 2 0.11 0.1 2.31
98 INT99865 Binding of Trpv2 4 0.48 1.13 2.25
99 INT203047 Gene_expression of CD274 16 0.52 12.32 2.21
100 INT152554 Regulation of Transcription of SLC6A4 3 0.62 1.52 2.18
101 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16
102 INT215611 Negative_regulation of Positive_regulation of Adora1 6 0.43 1.18 2.16
103 INT92542 Negative_regulation of Trpv2 8 0.59 1.54 2.15
104 INT94673 Positive_regulation of FAAH 5 0.50 7.77 2.08
105 INT55470 Regulation of Mtor 16 0.24 12.51 2.07
106 INT36293 Gene_expression of Mtor 24 0.25 14.5 2.04
107 INT57939 Negative_regulation of Gene_expression of Adora2a 4 0.36 0.15 2.02
108 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
109 INT195430 Regulation of Positive_regulation of SLC6A4 1 0.42 1.01 1.98
110 INT125974 Localization of Slc6a4 5 0.66 2.27 1.97
111 INT72785 Positive_regulation of Positive_regulation of Adora2a 2 0.10 1.34 1.96
112 INT107905 Gene_expression of BCL2L11 9 0.75 7.58 1.92
113 INT243017 Negative_regulation of Binding of Slc6a4 1 0.25 0.22 1.89
114 INT194847 Negative_regulation of Positive_regulation of Adora2a 3 0.32 4.52 1.88
115 INT50743 Positive_regulation of Trpc2 12 0.44 1.99 1.87
116 INT100689 Negative_regulation of JAK1 8 0.57 5.36 1.87
117 INT32558 Negative_regulation of ADORA1 5 0.12 2.77 1.86
118 INT124556 Negative_regulation of Positive_regulation of Adora1 3 0.51 1.2 1.81
119 INT85337 Negative_regulation of Slc9a3r2 5 0.34 2.32 1.8
120 INT141937 Negative_regulation of Regulation of SLC6A4 1 0.41 0.27 1.8
121 INT105920 Binding of SLC9A3R2 5 0.36 1.99 1.75
122 INT168519 Positive_regulation of Gene_expression of Adora1 4 0.61 0.75 1.75
123 INT44637 Positive_regulation of Slc9a3r2 18 0.55 7.27 1.72
124 INT278981 Negative_regulation of JAK3 5 0.46 2.12 1.69
125 INT261815 Regulation of Gene_expression of Trpv2 2 0.32 0.97 1.65
126 INT86545 Positive_regulation of Phosphorylation of Camk1g 1 0.62 0 1.65
127 INT206144 Phosphorylation of JAK1 6 0.57 1.77 1.64
128 INT86542 Positive_regulation of Camk1g 5 0.64 0.28 1.64
129 INT29763 Negative_regulation of Adora1 3 0.42 0 1.64
130 INT106534 Gene_expression of Dock9 3 0.65 1.62 1.63
131 INT86540 Phosphorylation of Camk1g 1 0.74 0 1.63
132 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6
133 INT107895 Positive_regulation of Gene_expression of Trpv2 4 0.46 0.98 1.6
134 INT119994 Negative_regulation of Trpv2 5 0.58 3.04 1.58
135 INT147808 Positive_regulation of Gene_expression of SLC6A4 4 0.50 1.03 1.57
136 INT143744 Regulation of FAAH 6 0.61 8.42 1.55
137 INT152720 Localization of Trpv2 6 0.69 2.71 1.54
138 INT76496 Localization of Adora2a 3 0.48 0.3 1.54
139 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
140 INT118311 Binding of Slc9a3r2 5 0.45 2.03 1.49
141 INT143743 Positive_regulation of Gene_expression of FAAH 8 0.60 6.42 1.46
142 INT141272 Binding of FAAH 7 0.48 8.27 1.46
143 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44
144 INT166764 Localization of Mtor 2 0.75 1.28 1.42
145 INT241721 Positive_regulation of Transcription of Adora1 3 0.50 1.39 1.41
146 INT108402 Negative_regulation of Gene_expression of FAAH 6 0.43 5.99 1.39
147 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
148 INT83553 Positive_regulation of Positive_regulation of Agtr1a 3 0.59 4.12 1.37
149 INT241737 Transcription of Adora1 3 0.72 0.89 1.32
150 INT107904 Positive_regulation of Gene_expression of BCL2L11 3 0.53 2.22 1.24
151 INT303667 Regulation of BCL2L11 3 0.16 1.03 1.21
152 INT228671 Negative_regulation of Phosphorylation of Mtor 8 0.50 1.77 1.2
153 INT155846 Transcription of JAK1 4 0.67 1.93 1.19
154 INT91595 Regulation of Gene_expression of Adora2a 1 0.52 0 1.19
155 INT115854 Transcription of Trpv2 4 0.53 0.89 1.18
156 INT39785 Positive_regulation of Transcription of Lnpep 2 0.50 0.47 1.18
157 INT47839 Localization of Slc6a4 4 0.79 0.96 1.14
158 INT76254 Positive_regulation of Positive_regulation of ADORA1 2 0.43 1.27 1.14
159 INT148072 Gene_expression of Agtr1a 5 0.75 9.41 1.13
160 INT147286 Negative_regulation of Regulation of Slc6a4 1 0.21 0 1.13
161 INT286596 Positive_regulation of Positive_regulation of SLC9A3R2 2 0.50 3.37 1.07
162 INT286597 Localization of SLC9A3R2 3 0.54 6.71 1.05
163 INT105922 Gene_expression of SLC9A3R2 6 0.48 2.09 1.04
164 INT128444 Phosphorylation of SLC6A4 2 0.61 0.49 1.02
165 INT151774 Positive_regulation of Mtor 38 0.45 20.15 1.01
166 INT129674 Regulation of Negative_regulation of Slc6a4 1 0.38 0.46 0.98
167 INT278975 Gene_expression of JAK3 3 0.52 1.03 0.97
168 INT198049 Positive_regulation of JAK2 16 0.58 5.35 0.96
169 INT52090 Transcription of Adora2a 3 0.41 0.33 0.96
170 INT226480 Positive_regulation of JAK3 4 0.45 0.96 0.95
171 INT72006 Positive_regulation of Negative_regulation of Adora2a 2 0.40 0.26 0.94
172 INT169336 Binding of Jak2 2 0.42 1.31 0.93
173 INT134040 Regulation of Jak2 3 0.41 1.07 0.92
174 INT131649 Positive_regulation of Negative_regulation of Slc6a4 2 0.44 0.32 0.91
175 INT286694 Positive_regulation of Localization of Slc6a4 1 0.26 0 0.9
176 INT132883 Gene_expression of Slc11a2 5 0.75 2.96 0.89
177 INT152101 Regulation of Transcription of Slc6a4 1 0.14 0 0.89
178 INT215606 Positive_regulation of Localization of Adora1 3 0.49 0.44 0.87
179 INT134037 Positive_regulation of Phosphorylation of Jak2 1 0.46 0.25 0.86
180 INT53660 Positive_regulation of Pcsk5 2 0.49 0.29 0.85
181 INT50744 Negative_regulation of Positive_regulation of Trpc2 1 0.21 0.51 0.85
182 INT229710 Localization of Agtr1a 3 0.60 0.57 0.84
183 INT92880 Localization of ADORA1 2 0.80 0.09 0.84
184 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81
185 INT271917 Phosphorylation of Mtor 11 0.13 6.76 0.78
186 INT299316 Binding of FIBP 2 0.01 1.36 0.78
187 INT302869 Phosphorylation of Adora2a 1 0.49 0.25 0.78
188 INT86548 Negative_regulation of Phosphorylation of Camk1g 1 0.52 0 0.78
189 INT302868 Positive_regulation of Phosphorylation of Adora2a 1 0.41 0.25 0.78
190 INT80147 Negative_regulation of Binding of Adora2a 2 0.43 0.15 0.77
191 INT193313 Gene_expression of PDCD1LG2 7 0.57 3.52 0.76
192 INT141115 Negative_regulation of Transcription of Lnpep 1 0.31 0 0.76
193 INT243015 Regulation of Binding of Slc6a4 1 0.16 0.43 0.75
194 INT89663 Localization of Adora2a 1 0.74 0.74 0.75
195 INT194852 Protein_catabolism of Adora2a 1 0.56 0.6 0.75
196 INT147809 Localization of SLC6A4 5 0.71 1.69 0.74
197 INT113512 Regulation of Gene_expression of ADORA1 1 0.11 0.19 0.73
198 INT250144 Positive_regulation of CD274 11 0.47 5.77 0.72
199 INT152301 Gene_expression of Slc9a3r2 3 0.53 1.48 0.72
200 INT119993 Regulation of Trpv2 2 0.22 0.07 0.72
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