GO:0014003

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Name oligodendrocyte development
Categary Process
Go Slim No
Go Link GO:0014003
Unique Molecular Interactions 105
Total Molecular Interactions 132
Total Single Events 781
Pain Genes Associated 22

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for oligodendrocyte development. They are ordered first by their pain relevance and then by number of times they were reported for oligodendrocyte development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77508 ST13 Negative_regulation of Gene_expression of CD9 1 0.09 0.5 0.54
2 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42
3 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42
4 INT223829 Binding of GSTM1 and GSTP1 2 0.41 2.78 0.39
5 INT345006 CSF2 Regulation of GSN 1 0.16 0.82 0.39
6 INT32761 Positive_regulation of Mrf Positive_regulation of Localization of Vip 1 0.08 0 0.38
7 INT345012 GSN Regulation of CCBE1 1 0.00 0.82 0.36
8 INT345010 GSN Regulation of DBP 1 0.26 0.81 0.36
9 INT254391 Binding of F13A1 and GSN 1 0.00 1.08 0.34
10 INT254393 Binding of FN1 and GSN 1 0.01 1.08 0.34
11 INT75643 NCOR2 Positive_regulation of Positive_regulation of EIF2B3 1 0.00 0 0.33
12 INT75641 AR Positive_regulation of Positive_regulation of EIF2B3 1 0.02 0 0.33
13 INT70661 Binding of Hrasls and Nkx2-2 1 0.02 0 0.24
14 INT223828 Binding of GSTP1 and MAPK8 1 0.06 1.8 0.21
15 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
16 INT2433 Mrf Positive_regulation of Mpo 1 0.33 0.65 0.18
17 INT28722 Binding of T2 and Hdac11 1 0.11 0.14 0.18
18 INT76196 Binding of HTR1A and EIF2B3 1 0.06 0 0.17
19 INT254392 Binding of CRP and GSN 1 0.12 0.33 0.16
20 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
21 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
22 INT345011 Binding of GSN and PTAFR 1 0.09 0.83 0.12
23 INT10730 CD9 Regulation of CD4 1 0.42 1.3 0.12
24 INT10732 NEUROD1 Regulation of CD9 1 0.49 1.29 0.12
25 INT129093 Binding of Lyn and TCHP 1 0.00 0.49 0.12
26 INT283719 Id2 Regulation of Regulation of Hes7 1 0.00 0.31 0.12
27 INT129092 Binding of GRP and Lyn 1 0.00 0.48 0.12
28 INT283710 Binding of Id2 and Hes7 1 0.01 0.13 0.11
29 INT223827 MAPK8 Positive_regulation of Gene_expression of GSTP1 1 0.12 0.88 0.1
30 INT28723 Negative_regulation of Binding of T2 and Hdac11 1 0.10 0.08 0.1
31 INT308749 Gene_expression of C11orf9 Positive_regulation of Gene_expression of MAG 1 0.13 0.08 0.09
32 INT129624 Bmp7 Positive_regulation of Gene_expression of Id2 1 0.26 0.31 0.08
33 INT129625 Id2 Positive_regulation of Gene_expression of Bmp7 1 0.24 0.31 0.08
34 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
35 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
36 INT283721 Binding of Lpin1 and Id2 1 0.38 0.18 0.08
37 INT278164 GSTM1 Positive_regulation of Transcription of GSTP1 1 0.57 0.94 0.07
38 INT129627 Bmp7 Positive_regulation of Id2 1 0.24 0.25 0.07
39 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
40 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
41 INT286563 Binding of Id2 and P1Ehs1 1 0.00 0.17 0.06
42 INT286591 Binding of PKD1 and Id2 1 0.07 0.17 0.06
43 INT223825 GSTP1 Negative_regulation of MAPK8 1 0.11 1.53 0.06
44 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
45 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
46 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
47 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
48 INT283720 Id2 Negative_regulation of Transcription of Cdkn2b 1 0.18 0.11 0.03
49 INT283722 Id2 Negative_regulation of Transcription of CDKN1A 1 0.45 0.11 0.03
50 INT283712 Id2 Regulation of Gene_expression of Fos 1 0.43 0 0.03
51 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
52 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
53 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
54 INT189546 Binding of CD9 and FN1 1 0.01 0.6 0
55 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
56 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
57 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
58 INT201534 RASSF1 Negative_regulation of ID2 1 0.33 1.41 0
59 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
60 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
61 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
62 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
63 INT308352 Binding of Ctnnd2 and Tcf7l2 1 0.15 0.74 0
64 INT197309 Ascl1 Regulation of Neurod1 1 0.01 0.13 0
65 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
66 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
67 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
68 INT201542 Positive_regulation of RASSF1 Negative_regulation of ID2 1 0.36 1.41 0
69 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
70 INT283717 Id2 Regulation of 4930579C15Rik 1 0.15 0.75 0
71 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
72 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
73 INT197315 Hes5 Regulation of Atoh1 1 0.00 0.14 0
74 INT256993 Binding of Cd9 and Cd81 1 0.18 0.22 0
75 INT283718 Binding of Id2 and Aatf 1 0.03 0.19 0
76 INT240011 Ass1 Positive_regulation of Gene_expression of Nkx2-2 1 0.00 0 0
77 INT256983 Binding of Cd9 and Ezr 1 0.06 0.12 0
78 INT201536 RASSF1 Regulation of ID2 1 0.41 1.42 0
79 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
80 INT197314 Hes5 Regulation of Ascl1 1 0.00 0.14 0
81 INT286590 Binding of ID2 and Pkd2 1 0.13 0.13 0
82 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
83 INT201533 RASSF1 Positive_regulation of Gene_expression of ID2 1 0.38 1.41 0
84 INT301366 Fgf18 Positive_regulation of Fgfr3 1 0.04 0.34 0
85 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
86 INT197307 Ascl1 Regulation of Neurod6 1 0.00 0.13 0
87 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
88 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
89 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
90 INT249606 Slc25a1 Positive_regulation of Sd 1 0.05 0 0
91 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
92 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
93 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for oligodendrocyte development. They are ordered first by their pain relevance and then by number of times they were reported in oligodendrocyte development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT189230 Gene_expression of GSN 12 0.75 25.04 7.6
2 INT254400 Negative_regulation of GSN 22 0.57 18.15 5.89
3 INT48840 Gene_expression of Nkx2-2 8 0.23 1.55 5.44
4 INT75645 Binding of EIF2B3 10 0.07 0.21 4.9
5 INT15257 Positive_regulation of Nkx2-2 10 0.21 1.75 4.2
6 INT51180 Regulation of Nkx2-2 5 0.26 2.16 4.14
7 INT8600 Binding of Nkx2-2 6 0.10 0.87 3.82
8 INT52227 Gene_expression of CD9 11 0.75 6.23 3.71
9 INT12785 Positive_regulation of Mrf 9 0.44 1.08 3.02
10 INT52228 Negative_regulation of Gene_expression of CD9 3 0.57 2.45 2.54
11 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
12 INT189239 Binding of GSN 11 0.36 9.34 1.93
13 INT39783 Positive_regulation of Sd 3 0.36 0.41 1.86
14 INT229906 Gene_expression of Cd9 1 0.51 1.29 1.84
15 INT135077 Binding of GSTP1 11 0.48 7.03 1.8
16 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
17 INT189226 Protein_catabolism of GSN 3 0.54 7.1 1.7
18 INT129610 Gene_expression of Id2 7 0.74 17.07 1.69
19 INT244735 Gene_expression of Ascl1 12 0.58 2.48 1.54
20 INT345015 Positive_regulation of Gene_expression of GSN 1 0.49 3.58 1.5
21 INT112845 Negative_regulation of Binding of Nkx2-2 2 0.12 0.14 1.47
22 INT132081 Regulation of Gene_expression of Nkx2-2 2 0.10 0.24 1.43
23 INT75647 Positive_regulation of Binding of EIF2B3 3 0.07 0.11 1.42
24 INT39781 Gene_expression of Sd 7 0.60 2.47 1.33
25 INT254397 Negative_regulation of Gene_expression of GSN 2 0.41 3.56 1.28
26 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
27 INT345013 Regulation of GSN 4 0.51 3.49 1.11
28 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
29 INT14632 Gene_expression of Mrf 4 0.14 0.75 0.87
30 INT254401 Positive_regulation of GSN 4 0.38 2 0.79
31 INT118469 Gene_expression of Fgfr3 5 0.72 6.98 0.75
32 INT138396 Transcription of Nkx2-2 1 0.26 0.05 0.75
33 INT138395 Positive_regulation of Transcription of Nkx2-2 1 0.19 0.05 0.75
34 INT75646 Positive_regulation of EIF2B3 2 0.06 0.11 0.68
35 INT25134 Positive_regulation of CD9 3 0.49 3.38 0.66
36 INT254402 Localization of GSN 2 0.78 2.73 0.63
37 INT129615 Positive_regulation of Id2 2 0.66 2.22 0.57
38 INT117091 Positive_regulation of Lyn 1 0.49 0.41 0.56
39 INT106022 Negative_regulation of GSTP1 5 0.59 2.12 0.55
40 INT19281 Gene_expression of C11orf9 2 0.50 0.18 0.55
41 INT120762 Regulation of GSTP1 2 0.45 3.66 0.54
42 INT18506 Negative_regulation of CD9 4 0.57 3.79 0.52
43 INT142972 Gene_expression of ID2 6 0.54 5.92 0.49
44 INT206484 Localization of Shh 2 0.75 1.14 0.46
45 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
46 INT48503 Positive_regulation of Positive_regulation of Nkx2-2 1 0.15 0 0.42
47 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
48 INT87406 Gene_expression of GSTP1 16 0.77 11.37 0.35
49 INT283683 Binding of Id2 5 0.35 0.8 0.35
50 INT345016 Regulation of Gene_expression of GSN 1 0.38 0.78 0.35
51 INT122619 Gene_expression of Nkx2-2 6 0.36 0.15 0.31
52 INT86395 Negative_regulation of Binding of EIF2B3 1 0.05 0.06 0.3
53 INT14633 Negative_regulation of Gene_expression of Mrf 1 0.08 0.53 0.27
54 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
55 INT208497 Localization of Nkx2-2 1 0.01 0 0.26
56 INT278169 Regulation of Regulation of GSTP1 1 0.45 1.1 0.25
57 INT129612 Positive_regulation of Gene_expression of Id2 4 0.67 3.61 0.22
58 INT310471 Regulation of Ascl1 1 0.34 0.19 0.22
59 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
60 INT70176 Negative_regulation of Sd 1 0.05 0.28 0.21
61 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
62 INT114371 Negative_regulation of Tcf7l2 1 0.05 0.7 0.2
63 INT120761 Positive_regulation of GSTP1 3 0.50 3.4 0.19
64 INT222191 Regulation of Gene_expression of CD9 1 0.07 0.38 0.19
65 INT222201 Positive_regulation of Gene_expression of CD9 1 0.18 0.37 0.19
66 INT254396 Negative_regulation of Transcription of GSN 1 0.36 0.78 0.19
67 INT254398 Transcription of GSN 1 0.44 0.78 0.19
68 INT308771 Positive_regulation of Gene_expression of C11orf9 1 0.39 0.18 0.18
69 INT52998 Regulation of CD9 2 0.44 1.6 0.17
70 INT310462 Positive_regulation of Gene_expression of Ascl1 1 0.37 0.52 0.17
71 INT50844 Positive_regulation of Positive_regulation of Mrf 1 0.32 0 0.17
72 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
73 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
74 INT310488 Binding of Ascl1 1 0.28 0.25 0.16
75 INT94712 Binding of Mrf 1 0.31 1.03 0.15
76 INT253190 Localization of Shh 2 0.77 1.06 0.13
77 INT31433 Binding of CD9 1 0.36 1.36 0.13
78 INT278171 Positive_regulation of Transcription of GSTP1 1 0.50 1.86 0.13
79 INT283702 Transcription of Id2 1 0.66 0.64 0.13
80 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
81 INT283708 Localization of Id2 2 0.71 0.72 0.11
82 INT142970 Positive_regulation of Gene_expression of ID2 2 0.40 2.39 0.11
83 INT142968 Negative_regulation of Gene_expression of ID2 1 0.19 0.98 0.11
84 INT308772 Positive_regulation of C11orf9 1 0.39 0.1 0.11
85 INT223834 Localization of GSTP1 2 0.70 1.28 0.1
86 INT120767 Negative_regulation of Gene_expression of GSTP1 3 0.42 1.15 0.09
87 INT142971 Negative_regulation of Positive_regulation of ID2 1 0.20 0.69 0.09
88 INT142969 Positive_regulation of ID2 1 0.21 0.68 0.09
89 INT310484 Positive_regulation of Ascl1 1 0.37 0.47 0.09
90 INT28720 Binding of Hdac11 1 0.26 0.07 0.09
91 INT270442 Transcription of Shh 1 0.53 0.25 0.09
92 INT213515 Binding of Shh 8 0.37 1.92 0.08
93 INT129614 Positive_regulation of Positive_regulation of Id2 1 0.48 0.31 0.08
94 INT120771 Negative_regulation of Positive_regulation of GSTP1 1 0.30 0.39 0.08
95 INT270453 Regulation of Shh 1 0.27 0.83 0.08
96 INT308769 Negative_regulation of C11orf9 1 0.36 0.15 0.08
97 INT250839 Binding of Fgfr3 1 0.16 0.19 0.08
98 INT120766 Regulation of Positive_regulation of GSTP1 1 0.32 0.39 0.08
99 INT205973 Binding of SHH 3 0.35 1.03 0.07
100 INT278173 Transcription of GSTP1 1 0.68 0.93 0.07
101 INT308785 Regulation of C11orf9 1 0.23 0.2 0.07
102 INT256862 Regulation of Shh 1 0.25 0 0.07
103 INT298251 Gene_expression of Hes5 2 0.45 0.39 0.06
104 INT129613 Regulation of Gene_expression of Id2 1 0.43 0.24 0.06
105 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
106 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
107 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
108 INT122620 Negative_regulation of Gene_expression of Nkx2-2 1 0.20 0 0.04
109 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
110 INT253181 Transcription of Shh 1 0.68 0.54 0.03
111 INT214538 Binding of Sd 6 0.26 1.31 0
112 INT203874 Positive_regulation of Gene_expression of GSTP1 3 0.49 1.91 0
113 INT210256 Positive_regulation of Tcf7l2 2 0.28 1.25 0
114 INT276327 Positive_regulation of Gene_expression of Fgfr3 2 0.43 1.83 0
115 INT243057 Positive_regulation of Fgfr3 1 0.46 0.79 0
116 INT303553 Regulation of Gene_expression of Fgfr3 1 0.25 0.3 0
117 INT305470 Regulation of Gene_expression of GSTP1 1 0.06 0.59 0
118 INT203877 Phosphorylation of GSTP1 1 0.79 0.22 0
119 INT286577 Binding of ID2 1 0.19 0.12 0
120 INT243058 Positive_regulation of Positive_regulation of Fgfr3 1 0.46 0.8 0
121 INT143655 Transcription of Nkx2-2 1 0.58 0 0
122 INT283686 Regulation of Id2 1 0.26 0.31 0
123 INT298236 Localization of Hes5 1 0.51 0.39 0
124 INT350933 Gene_expression of Hdac11 1 0.33 0.12 0
125 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
126 INT203870 Negative_regulation of Binding of GSTP1 1 0.42 0.22 0
127 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
128 INT301359 Positive_regulation of Fgfr3 1 0.19 0.64 0
129 INT281642 Localization of Sd 1 0.26 0 0
130 INT143654 Positive_regulation of Transcription of Nkx2-2 1 0.56 0 0
131 INT290929 Binding of Shh 1 0.31 0.1 0
132 INT301357 Negative_regulation of Positive_regulation of Fgfr3 1 0.16 0.35 0
133 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
134 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
135 INT308764 Binding of C11orf9 1 0.34 0 0
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