GO:0014037

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Name Schwann cell differentiation
Categary Process
Go Slim No
Go Link GO:0014037
Unique Molecular Interactions 43
Total Molecular Interactions 53
Total Single Events 395
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for Schwann cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for Schwann cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT290957 Lsd Positive_regulation of Gene_expression of Egr2 1 0.11 0.1 0.26
2 INT273935 Crem Regulation of Gene_expression of Egr2 1 0.05 0.16 0.26
3 INT279799 ATP6V0A2 Regulation of ERBB3 1 0.00 1.77 0.12
4 INT211996 Erbb3 Positive_regulation of Nrg1 2 0.03 0.67 0.11
5 INT325654 Binding of Nab1 and Gopc 1 0.04 0.63 0.09
6 INT312839 Egr2 Regulation of Gene_expression of Mbp 1 0.32 0.16 0.09
7 INT312843 Egr2 Regulation of Gene_expression of Plp1 1 0.31 0.16 0.09
8 INT312840 Egr2 Regulation of Gene_expression of Mag 1 0.31 0.16 0.09
9 INT312846 Egr2 Regulation of Gene_expression of Pmp22 1 0.35 0.16 0.09
10 INT325653 Positive_regulation of Binding of Nab1 and Gopc 1 0.05 0.63 0.09
11 INT307663 Binding of Pmp22 and Egr2 1 0.33 0.39 0.08
12 INT319309 Egr2 Regulation of Ptk2b 1 0.29 0.37 0.07
13 INT319306 Egr2 Regulation of Pitpnm2 1 0.12 0.37 0.07
14 INT267004 Mdk Positive_regulation of Egr2 1 0.04 0.1 0.06
15 INT267013 Pik3cg Positive_regulation of Egr2 1 0.01 0.1 0.06
16 INT217111 Binding of Egr2 and Hoxa2 1 0.35 0.21 0.03
17 INT287268 Binding of ERBB2 and ERBB3 5 0.16 2.74 0
18 INT217112 Egr2 Regulation of Hoxa2 1 0.69 0 0
19 INT243768 Egr2 Regulation of Gene_expression of Nab2 1 0.47 0.14 0
20 INT259451 Binding of DHCR7 and Cyp11a1 1 0.01 0.3 0
21 INT279802 ATP6V0A2 Negative_regulation of ERBB3 1 0.00 1.96 0
22 INT243767 Egr2 Regulation of Gene_expression of Nab1 1 0.63 0.14 0
23 INT335215 RDH5 Positive_regulation of Negative_regulation of ERBB3 1 0.03 0.98 0
24 INT240122 Nab2 Regulation of Egr1 1 0.09 0.59 0
25 INT217107 Negative_regulation of Egr2 Regulation of Hoxa2 1 0.48 0 0
26 INT243770 Egr1 Regulation of Nab2 1 0.28 0.09 0
27 INT341013 Binding of Erbb3 and Nrg1 1 0.04 0.14 0
28 INT217109 Hoxa2 Positive_regulation of Egr2 1 0.56 0.43 0
29 INT287269 Binding of ERBB3 and PIK3CG 1 0.11 0.74 0
30 INT242178 CYP19A1 Regulation of Cyp11a1 1 0.01 0.35 0
31 INT242179 Cyp11a1 Regulation of CYP19A1 1 0.01 0.7 0
32 INT294087 Negative_regulation of Binding of ERBB2 and ERBB3 1 0.08 0.6 0
33 INT243769 Binding of Egr2 and Nab2 1 0.39 0.15 0
34 INT259452 Binding of STAR and Cyp11a1 1 0.25 0.06 0
35 INT341014 Positive_regulation of Binding of Erbb3 and Nrg1 1 0.06 0.14 0
36 INT341022 PIK3CB Regulation of Gene_expression of Erbb3 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for Schwann cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in Schwann cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT90715 Gene_expression of Egr2 12 0.73 1.64 7.17
2 INT94277 Positive_regulation of Gene_expression of Egr2 7 0.49 0.69 4.4
3 INT217102 Gene_expression of Egr2 50 0.78 10.91 3.89
4 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7
5 INT31580 Negative_regulation of Cyp11a1 14 0.57 3.48 3.61
6 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01
7 INT8095 Gene_expression of ERBB3 47 0.77 24.85 2.82
8 INT5863 Positive_regulation of Egr2 7 0.40 1.44 2.64
9 INT217094 Positive_regulation of Egr2 17 0.69 5.31 1.87
10 INT112339 Localization of Cyp11a1 2 0.71 0.94 1.68
11 INT10570 Positive_regulation of Cyp11a1 9 0.47 2.67 1.4
12 INT10578 Transcription of Cyp11a1 3 0.53 0.84 0.93
13 INT159982 Negative_regulation of ERBB3 11 0.26 8.44 0.75
14 INT147212 Negative_regulation of Gene_expression of Egr2 1 0.38 0.1 0.7
15 INT90718 Regulation of Gene_expression of Egr2 2 0.43 0.41 0.67
16 INT99892 Negative_regulation of Positive_regulation of Egr2 1 0.20 0.1 0.45
17 INT349709 Regulation of Transcription of Egr2 1 0.43 0 0.45
18 INT349697 Transcription of Egr2 1 0.68 0 0.45
19 INT68725 Regulation of Cyp11a1 6 0.19 2.62 0.44
20 INT121113 Protein_catabolism of Cyp11a1 2 0.65 0.37 0.44
21 INT217095 Regulation of Gene_expression of Egr2 2 0.62 0.32 0.4
22 INT243761 Positive_regulation of Positive_regulation of Egr2 2 0.47 0.47 0.36
23 INT243751 Localization of Egr2 1 0.75 0.18 0.34
24 INT243750 Transcription of Egr2 2 0.69 0.16 0.32
25 INT142132 Positive_regulation of Erbb3 3 0.27 0.82 0.3
26 INT21789 Positive_regulation of ERBB3 7 0.47 4.26 0.29
27 INT217097 Regulation of Egr2 3 0.62 1.4 0.29
28 INT117760 Regulation of Gene_expression of Cyp11a1 2 0.42 0.36 0.25
29 INT217096 Negative_regulation of Egr2 10 0.58 3.23 0.24
30 INT10575 Positive_regulation of Transcription of Cyp11a1 1 0.05 0 0.17
31 INT217088 Positive_regulation of Gene_expression of Egr2 3 0.50 1.49 0.16
32 INT10572 Positive_regulation of Positive_regulation of Cyp11a1 1 0.05 0 0.16
33 INT231264 Gene_expression of Erbb3 9 0.35 1.45 0.15
34 INT217100 Negative_regulation of Gene_expression of Egr2 1 0.57 0.44 0.12
35 INT249643 Positive_regulation of Localization of Nab1 1 0.07 0.54 0.11
36 INT249638 Localization of Nab1 1 0.10 0.54 0.11
37 INT8098 Positive_regulation of Gene_expression of ERBB3 7 0.69 3.79 0.1
38 INT220434 Negative_regulation of Gene_expression of ERBB3 1 0.03 0.4 0.1
39 INT184509 Regulation of Negative_regulation of ERBB3 1 0.01 0.47 0.1
40 INT243759 Gene_expression of Nab1 6 0.75 2.67 0.09
41 INT325615 Positive_regulation of Nab1 1 0.04 0.62 0.09
42 INT8099 Binding of ERBB3 7 0.36 3.09 0.08
43 INT243762 Binding of Egr2 1 0.37 0.25 0.07
44 INT185035 Regulation of ERBB3 3 0.42 6.5 0.06
45 INT140315 Regulation of Positive_regulation of Cyp11a1 1 0.19 0.07 0.05
46 INT266932 Transcription of ERBB3 4 0.43 1.7 0
47 INT279809 Localization of ERBB3 3 0.01 2.08 0
48 INT243757 Binding of Nab1 1 0.32 0.1 0
49 INT282444 Regulation of Gene_expression of Erbb3 1 0.11 0.84 0
50 INT267035 Regulation of Egr2 1 0.10 0.1 0
51 INT243763 Gene_expression of Nab2 1 0.70 0.14 0
52 INT243754 Binding of Nab2 1 0.32 0.1 0
53 INT282449 Regulation of Positive_regulation of Erbb3 1 0.11 0.91 0
54 INT340961 Positive_regulation of Gene_expression of Erbb3 1 0.09 0 0
55 INT340957 Binding of Erbb3 1 0.07 0.13 0
56 INT286986 Phosphorylation of ERBB3 1 0.28 0.83 0
57 INT340950 Negative_regulation of Erbb3 1 0.08 0 0
58 INT340972 Negative_regulation of Gene_expression of Erbb3 1 0.08 0 0
59 INT249639 Regulation of Nab1 1 0.04 0.31 0
60 INT340944 Positive_regulation of Phosphorylation of Erbb3 1 0.09 0.13 0
61 INT249640 Negative_regulation of Nab1 1 0.07 0.32 0
62 INT259446 Positive_regulation of Gene_expression of Cyp11a1 1 0.28 0 0
63 INT340958 Negative_regulation of Binding of Erbb3 1 0.08 0 0
64 INT313602 Negative_regulation of Binding of ERBB3 1 0.18 0.58 0
65 INT243760 Negative_regulation of Gene_expression of Nab1 1 0.41 0.22 0
66 INT340945 Phosphorylation of Erbb3 1 0.12 0.13 0
67 INT217090 Negative_regulation of Positive_regulation of Egr2 1 0.42 0 0
68 INT243752 Positive_regulation of Negative_regulation of Egr2 1 0.47 0.23 0
69 INT340968 Positive_regulation of Binding of Erbb3 1 0.09 0.13 0
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