GO:0014054

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Name positive regulation of gamma-aminobutyric acid secretion
Categary Process
Go Slim No
Go Link GO:0014054
Unique Molecular Interactions 215
Total Molecular Interactions 335
Total Single Events 2890
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of gamma-aminobutyric acid secretion. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of gamma-aminobutyric acid secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44
2 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39
3 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29
4 INT26677 Penk Regulation of Localization of Trh 5 0.50 0 3.05
5 INT137230 Trh Regulation of Gene_expression of Oprd1 1 0.01 1.62 2.75
6 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
7 INT26676 Pomc Regulation of Localization of Trh 3 0.14 0 1.73
8 INT32839 Binding of Trh and Penk 2 0.42 0 1.63
9 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
10 INT33988 TRH Regulation of Localization of IGKV1D-39 1 0.12 0.47 1.35
11 INT124925 Negative_regulation of Slc6a1 Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
12 INT197231 Grik1 Regulation of Gabrg1 1 0.19 0.13 1.22
13 INT25036 TRH Regulation of Prl 4 0.27 1.75 1.09
14 INT7927 Penk Regulation of Trh 2 0.26 0.66 1.09
15 INT34900 Trh Positive_regulation of Localization of Prl 1 0.05 0 1.09
16 INT17414 TRH Positive_regulation of Prl 4 0.47 0 1.07
17 INT57509 Trh Negative_regulation of Adarb1 1 0.02 0.22 1.05
18 INT25155 TRH Positive_regulation of PRL 2 0.50 0.4 1
19 INT60208 Binding of Htr1a and Htr2c 2 0.52 0.25 1
20 INT90561 Slc6a1 Negative_regulation of Abat 1 0.02 0.25 0.91
21 INT32840 Regulation of Binding of Trh and Penk 1 0.26 0 0.91
22 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
23 INT17416 TRH Positive_regulation of Localization of Prl 1 0.47 0 0.85
24 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
25 INT7926 Regulation of Penk Regulation of Trh 1 0.26 0.66 0.8
26 INT52561 Trh Positive_regulation of Localization of Lhb 1 0.01 0.14 0.77
27 INT3570 Trh Regulation of Localization of Gnrhr 2 0.26 0.3 0.75
28 INT196799 Prkaca Positive_regulation of Phosphorylation of Trh 1 0.02 0 0.74
29 INT41919 Binding of Tacr1 and Trh 1 0.06 0 0.74
30 INT43717 Positive_regulation of Binding of Trh and Penk 1 0.56 0 0.72
31 INT197234 Grik1 Positive_regulation of Localization of Gabrg1 1 0.15 0.82 0.71
32 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
33 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
34 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
35 INT40763 Trh Negative_regulation of Penk 1 0.19 0 0.65
36 INT107330 Binding of Adarb1 and Trh 1 0.01 0 0.65
37 INT40762 Trh Negative_regulation of Prss12 1 0.06 0 0.65
38 INT197238 Grik1 Regulation of Gene_expression of Gabrg1 1 0.17 0.13 0.64
39 INT6465 Trh Regulation of Negative_regulation of Npr1 1 0.01 0 0.63
40 INT3617 Trh Regulation of Localization of Gh1 3 0.65 0.55 0.62
41 INT197239 Grik1 Regulation of Localization of Gabrg1 1 0.10 0.56 0.61
42 INT201294 Negative_regulation of Grik1 Negative_regulation of Gabrg1 1 0.30 0 0.6
43 INT40153 Gnrh1 Regulation of Trh 1 0.47 0 0.59
44 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
45 INT25156 TRH Regulation of PRL 2 0.27 0.81 0.56
46 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56
47 INT10079 Cp Regulation of Trh 1 0.01 0.59 0.53
48 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53
49 INT34368 TRH Positive_regulation of GHRH 1 0.23 0.4 0.53
50 INT49696 Trh Regulation of GH1 2 0.02 0.22 0.52
51 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
52 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
53 INT222524 Abat Negative_regulation of Localization of Trh 1 0.02 0.16 0.51
54 INT34980 Regulation of Trh Positive_regulation of Localization of Prl 1 0.50 0 0.49
55 INT17610 Binding of Ctse and Trh 1 0.27 0.89 0.49
56 INT30801 Penk Negative_regulation of Trh 1 0.09 0 0.49
57 INT61510 Binding of Trh and Gm14673 1 0.01 0 0.48
58 INT30802 Pomc Negative_regulation of Trh 1 0.11 0 0.48
59 INT17463 Trh Regulation of Localization of Prl 2 0.30 0.22 0.47
60 INT34982 Trh Regulation of Dbi 1 0.12 0 0.47
61 INT34984 Negative_regulation of Trh Regulation of Dbi 1 0.19 0 0.47
62 INT35167 Adrb2 Positive_regulation of Trh 1 0.05 0 0.45
63 INT19906 Positive_regulation of Trh Regulation of Prl 2 0.04 0.47 0.43
64 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
65 INT32161 Negative_regulation of Trh Positive_regulation of Prl 1 0.48 0 0.42
66 INT34985 Gene_expression of Pomc Positive_regulation of Localization of Trh 1 0.09 0 0.42
67 INT17415 Negative_regulation of TRH Positive_regulation of Prl 1 0.44 0 0.42
68 INT34983 Gene_expression of Dbi Positive_regulation of Localization of Trh 1 0.22 0 0.42
69 INT44312 Binding of Trh and Pag1 1 0.05 0.36 0.41
70 INT196797 Trh Negative_regulation of Prkaca 1 0.01 0 0.41
71 INT223474 Binding of Grik1 and P2rx3 1 0.03 0.36 0.4
72 INT35201 Trh Regulation of Tshb 1 0.01 0.28 0.39
73 INT33713 Binding of ITPR3 and Trh 1 0.00 0.86 0.39
74 INT196800 Trh Negative_regulation of Ppp1cc 1 0.01 0 0.39
75 INT196796 Ppp1r1b Negative_regulation of Phosphorylation of Trh 1 0.01 0 0.39
76 INT3634 Trh Regulation of Gh1 3 0.20 0.23 0.38
77 INT105770 SST Negative_regulation of Localization of TRH 1 0.17 0.54 0.38
78 INT45798 TRH Regulation of Lhb 1 0.36 0.09 0.38
79 INT3616 Trh Positive_regulation of Localization of Gh1 4 0.73 0.49 0.36
80 INT77494 PREP Positive_regulation of TRH 1 0.16 0 0.36
81 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
82 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
83 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
84 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
85 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
86 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
87 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
88 INT29118 Trh Regulation of Oprd1 1 0.24 0.79 0.31
89 INT196798 Trh Positive_regulation of Phosphorylation of Ppp1r1b 1 0.01 0 0.3
90 INT73053 Prl Positive_regulation of Trh 1 0.22 0 0.3
91 INT222529 Binding of Trh and Vip 1 0.07 0.09 0.29
92 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
93 INT3638 Trh Regulation of Localization of Gnrh1 1 0.17 0 0.29
94 INT40151 Nts Regulation of Trh 1 0.21 0 0.29
95 INT40152 Sst Regulation of Trh 1 0.22 0 0.29
96 INT41192 Trh Positive_regulation of Localization of POMC 1 0.04 0 0.29
97 INT25375 Trh Regulation of Gh 1 0.04 1.01 0.28
98 INT17351 Npy Regulation of Trh 1 0.46 0 0.28
99 INT3569 Trh Negative_regulation of Positive_regulation of Gh1 1 0.20 0 0.27
100 INT3574 Trh Negative_regulation of Localization of Gh1 1 0.15 0 0.27
101 INT44443 GNRH1 Positive_regulation of Localization of TRH 1 0.08 0.19 0.26
102 INT205701 P2rx7 Positive_regulation of Il1 1 0.04 0.8 0.25
103 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
104 INT197235 Binding of Grik1 and Kars 1 0.32 0.1 0.25
105 INT122232 Trh Positive_regulation of Positive_regulation of LH 1 0.18 0 0.24
106 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24
107 INT122225 Trh Positive_regulation of Gh1 1 0.06 0 0.24
108 INT122222 Trh Positive_regulation of LH 1 0.18 0 0.24
109 INT25247 TRH Regulation of CGA 1 0.26 0 0.24
110 INT49682 Positive_regulation of Trh Positive_regulation of Prl 1 0.05 0.26 0.23
111 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
112 INT63703 Regulation of TRH Positive_regulation of Prl 1 0.07 0 0.23
113 INT20186 TRH Regulation of Gene_expression of Gh 1 0.22 0.54 0.22
114 INT19905 Trh Regulation of Gnrhr 1 0.00 0.25 0.22
115 INT107219 Binding of P2rx7 and Atp5o 1 0.03 0.07 0.21
116 INT216946 P2rx7 Regulation of Il10 1 0.28 0.17 0.21
117 INT107223 APEH Negative_regulation of P2rx7 1 0.00 0.13 0.21
118 INT33714 Positive_regulation of Binding of ITPR3 and Trh 1 0.00 0.46 0.21
119 INT53230 Trh Positive_regulation of Tshb 1 0.55 0.2 0.2
120 INT83585 Trh Positive_regulation of Mc1r 1 0.50 0.35 0.2
121 INT205710 CAMP Positive_regulation of P2rx7 1 0.02 0.47 0.19
122 INT3635 Trh Regulation of Localization of Tshb 1 0.35 0.3 0.19
123 INT122236 Gnrh1 Positive_regulation of Trh 1 0.29 0 0.19
124 INT3619 Trh Positive_regulation of Localization of Gnrhr 2 0.48 0.2 0.18
125 INT342744 Ddc Regulation of Trh 1 0.02 0.37 0.18
126 INT60348 Trh Positive_regulation of Positive_regulation of Acot1 1 0.29 0.44 0.17
127 INT11791 TRH Regulation of Localization of PRL 1 0.18 0 0.17
128 INT10291 Trh Regulation of CTSC 1 0.01 0 0.16
129 INT32286 POMC Negative_regulation of Trh 1 0.01 0 0.15
130 INT74070 Trh Regulation of Lhb 1 0.02 0.27 0.15
131 INT32285 POMC Regulation of Trh 1 0.01 0 0.15
132 INT32287 POMC Regulation of Localization of Trh 1 0.03 0 0.15
133 INT44393 Vip Positive_regulation of Localization of Trh 1 0.51 0 0.14
134 INT32294 ENG Positive_regulation of Trh 1 0.01 0 0.13
135 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 0.41 0.18 0.13
136 INT34443 Negative_regulation of Binding of Trh and Ptprg 1 0.20 0.08 0.12
137 INT216945 Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1 1 0.14 0.18 0.12
138 INT34445 Binding of Trh and Ptprg 1 0.23 0.08 0.12
139 INT74504 Binding of P2rx7 and Rp2 1 0.02 0.19 0.11
140 INT83584 Binding of Mc1r and Trh 1 0.36 0.17 0.1
141 INT33323 Regulation of Trh Positive_regulation of Prl 1 0.30 0 0.1
142 INT3562 Trh Positive_regulation of Klkb1 1 0.10 0 0.1
143 INT34932 NA Positive_regulation of Localization of Trh 1 0.01 0 0.1
144 INT33712 Trh Positive_regulation of Localization of ITPR3 1 0.00 0.8 0.1
145 INT27051 Trhde Regulation of Negative_regulation of Trh 1 0.17 0 0.09
146 INT205708 Binding of Icam1 and P2rx7 1 0.08 1.03 0.09
147 INT32288 POMC Regulation of Positive_regulation of Trh 1 0.03 0 0.09
148 INT174093 Htr2c Regulation of Gene_expression of Csf2 1 0.00 0 0.09
149 INT217036 IRF6 Positive_regulation of Gene_expression of P2rx7 1 0.02 0 0.09
150 INT270824 Binding of P2rx7 and Panx1 1 0.34 0.15 0.09
151 INT222483 Trh Regulation of Gene_expression of Gh1 1 0.03 0 0.09
152 INT174070 Htr2c Positive_regulation of Itpr3 1 0.00 0 0.09
153 INT218733 Trh Positive_regulation of Gene_expression of Hdc 1 0.27 0 0.09
154 INT32290 ENG Regulation of Positive_regulation of Trh 1 0.01 0 0.09
155 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09
156 INT1387 Binding of Gnrh1 and Trh 1 0.29 0 0.08
157 INT33324 Regulation of Binding of Prl and Trh 1 0.50 0 0.08
158 INT33325 Binding of Prl and Trh 1 0.42 0 0.08
159 INT1389 Binding of LH and Trh 1 0.16 0 0.08
160 INT243156 Positive_regulation of P2rx7 Positive_regulation of NOS1 1 0.00 0.08 0.08
161 INT1386 Negative_regulation of Binding of and Trh 1 0.18 0 0.08
162 INT1391 Negative_regulation of Binding of Gnrh1 and Trh 1 0.34 0 0.08
163 INT270829 P2rx7 Positive_regulation of Panx1 1 0.66 0.08 0.08
164 INT340420 Hmmr Regulation of P2rx7 1 0.01 1.12 0.08
165 INT83586 Binding of MC2R and Trh 1 0.02 0.19 0.07
166 INT34448 Trh Negative_regulation of Negative_regulation of Ptprg 1 0.23 0 0.07
167 INT83587 Binding of MC4R and Trh 1 0.01 0.19 0.07
168 INT270835 Positive_regulation of P2rx7 Positive_regulation of Localization of DPEP1 1 0.04 0.08 0.07
169 INT83588 Binding of MC3R and Trh 1 0.28 0.19 0.07
170 INT34450 Pck1 Regulation of Binding of Trh 1 0.15 0 0.07
171 INT83589 Binding of CALCRL and Trh 1 0.01 0.18 0.07
172 INT53228 Negative_regulation of Trh Positive_regulation of Tshb 1 0.47 0.06 0.06
173 INT3620 Trh Positive_regulation of Positive_regulation of Gh1 1 0.49 0 0.06
174 INT17919 Trh Positive_regulation of Fos 1 0.40 0.14 0.06
175 INT215036 Gh Positive_regulation of Gene_expression of Trh 1 0.08 1.4 0.06
176 INT222487 Trh Negative_regulation of Nmb 1 0.05 0.26 0.05
177 INT198619 CRH Negative_regulation of TRH 1 0.18 0.47 0.05
178 INT53229 Trh Regulation of Gene_expression of Tshb 1 0.49 0.05 0.05
179 INT340427 Positive_regulation of P2rx7 Positive_regulation of Regulation of Pkhd1 1 0.01 1 0.05
180 INT270825 P2rx7 Positive_regulation of Slc37a4 1 0.01 0 0.04
181 INT217590 Binding of Trh and Trhr2 1 0.04 0 0.04
182 INT321294 Ins1 Positive_regulation of Trh 1 0.00 0.08 0.04
183 INT273117 Trh Positive_regulation of Rps6kb1 1 0.01 0.09 0.04
184 INT222562 Trh Regulation of Localization of LH 1 0.04 0 0.03
185 INT222468 Nmb Positive_regulation of Localization of Trh 1 0.05 0.28 0.03
186 INT222510 Nmb Positive_regulation of Trh 1 0.05 0.28 0.03
187 INT44230 Negative_regulation of Binding of PLOD1 and TRH 1 0.19 0.9 0
188 INT44228 TRH Regulation of PLOD1 1 0.12 0.9 0
189 INT39202 TRH Regulation of GH1 1 0.22 0 0
190 INT217031 Binding of P2rx7 and Positive_regulation of Casp1 1 0.02 0 0
191 INT44227 Binding of PLOD1 and TRH 1 0.17 0.9 0
192 INT217032 Binding of P2rx7 and Positive_regulation of Il1 1 0.02 0 0
193 INT44233 Binding of FSHR and TRH 1 0.34 0.9 0
194 INT218731 Lep Positive_regulation of Gene_expression of Trh 1 0.19 0.07 0
195 INT216942 Positive_regulation of P2rx7 Positive_regulation of Casp1 1 0.14 0 0
196 INT307460 P2rx7 Positive_regulation of Phosphorylation of Gsk3a 1 0.02 0 0
197 INT222496 Trh Positive_regulation of Gene_expression of Prl 1 0.10 0 0
198 INT215035 Trh Positive_regulation of Gh 1 0.07 0.89 0
199 INT44229 TRH Regulation of FSHR 1 0.11 0.9 0
200 INT39205 TRH Positive_regulation of GH1 1 0.44 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of gamma-aminobutyric acid secretion. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of gamma-aminobutyric acid secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT339 Regulation of Trh 156 0.62 39.27 83.55
2 INT403 Localization of Trh 241 0.81 28.55 81.45
3 INT1376 Binding of Trh 121 0.48 20 69.86
4 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83
5 INT2323 Gene_expression of Trh 146 0.78 29.92 49.5
6 INT989 Negative_regulation of Trh 90 0.59 15.45 43.63
7 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
8 INT61665 Phosphorylation of Trh 53 0.79 2.26 23.9
9 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
10 INT1327 Regulation of Localization of Trh 45 0.62 6.05 22.09
11 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
12 INT124670 Gene_expression of Grik1 53 0.77 4.83 19.13
13 INT14419 Negative_regulation of Localization of Trh 40 0.59 2.04 17.42
14 INT13209 Regulation of Binding of Trh 19 0.62 2.84 16.26
15 INT197210 Positive_regulation of Grik1 24 0.69 3.15 16.24
16 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
17 INT18001 Positive_regulation of Htr2c 21 0.67 7.63 11.39
18 INT23825 Negative_regulation of Binding of Trh 17 0.59 1.62 11.24
19 INT987 Localization of TRH 37 0.78 10.53 11.1
20 INT10009 Positive_regulation of TRH 31 0.67 8.94 11.03
21 INT8963 Gene_expression of Trh 25 0.68 7.5 10.97
22 INT8966 Regulation of Trh 12 0.62 2.73 10.79
23 INT3637 Positive_regulation of Localization of Trh 33 0.70 2.13 10.55
24 INT143964 Positive_regulation of Phosphorylation of Trh 10 0.20 0.1 10.54
25 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
26 INT56775 Binding of Htr2c 16 0.47 3.77 8.74
27 INT892 Regulation of TRH 23 0.60 8.46 8.54
28 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
29 INT15459 Gene_expression of TRH 17 0.78 4.89 8.17
30 INT95317 Positive_regulation of Slc6a1 6 0.69 5.91 7.94
31 INT9032 Regulation of Htr2c 11 0.60 2.77 7.81
32 INT9932 Positive_regulation of Positive_regulation of Trh 13 0.50 1.8 7.63
33 INT105528 Negative_regulation of Slc6a1 7 0.57 2.79 7.32
34 INT112211 Gene_expression of Slc6a1 8 0.78 4.48 6.86
35 INT197216 Localization of Grik1 9 0.80 0.39 6.78
36 INT112209 Positive_regulation of Gene_expression of Slc6a1 8 0.69 3.92 6.44
37 INT7923 Transcription of Trh 14 0.72 4.44 6.32
38 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
39 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
40 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
41 INT95313 Gene_expression of Slc6a1 6 0.76 3.96 6.14
42 INT49477 Gene_expression of Htr2c 12 0.75 3.26 5.73
43 INT34440 Negative_regulation of Positive_regulation of Trh 12 0.59 0 5.7
44 INT31648 Binding of Trh 11 0.48 2.09 5.48
45 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
46 INT10078 Positive_regulation of Gene_expression of Trh 17 0.50 4.23 5.19
47 INT112210 Regulation of Slc6a1 8 0.62 6.75 4.96
48 INT197219 Positive_regulation of Gene_expression of Grik1 5 0.69 0.83 4.67
49 INT8965 Positive_regulation of Trh 11 0.57 5.28 4.46
50 INT197230 Regulation of Positive_regulation of Grik1 4 0.45 0 4.42
51 INT8964 Regulation of Gene_expression of Trh 1 0.22 1.78 4.4
52 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
53 INT5015 Regulation of Gene_expression of Trh 9 0.62 6.47 4.25
54 INT52402 Negative_regulation of Htr2c 7 0.42 1.46 4.21
55 INT90555 Negative_regulation of Slc6a1 5 0.58 2.78 4.12
56 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
57 INT131969 Regulation of Grik1 6 0.61 0.57 3.69
58 INT197207 Negative_regulation of Grik1 5 0.43 1.91 3.5
59 INT63621 Transcription of Htr2c 6 0.52 0.62 3.49
60 INT949 Negative_regulation of TRH 12 0.43 3.06 3.4
61 INT55236 Regulation of Htr2c 6 0.44 3.31 3.36
62 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
63 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
64 INT34814 Negative_regulation of Trh 5 0.43 0.36 2.8
65 INT65000 Positive_regulation of Positive_regulation of Htr2c 4 0.67 0.69 2.8
66 INT2324 Positive_regulation of Regulation of Trh 7 0.50 2.22 2.65
67 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
68 INT153960 Negative_regulation of Gene_expression of Slc6a1 1 0.42 2.4 2.54
69 INT27267 Localization of Trh 11 0.80 1.76 2.47
70 INT59531 Positive_regulation of Transcription of Trh 6 0.69 1.31 2.42
71 INT988 Positive_regulation of Negative_regulation of Trh 3 0.50 0 2.39
72 INT325972 Negative_regulation of Binding of Slc6a1 1 0.02 0.52 2.38
73 INT325975 Binding of Slc6a1 1 0.02 0.52 2.37
74 INT25159 Regulation of Positive_regulation of TRH 4 0.44 0.35 2.28
75 INT77309 Positive_regulation of Htr2c 3 0.49 2.72 2.25
76 INT64505 Localization of Htr2c 3 0.78 0.87 2.24
77 INT69020 Gene_expression of Htr2c 9 0.74 6.09 2.22
78 INT16285 Regulation of Negative_regulation of Trh 3 0.62 0.9 2.22
79 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
80 INT14536 Positive_regulation of Gene_expression of Trh 4 0.50 0.54 1.9
81 INT133703 Negative_regulation of Phosphorylation of Trh 4 0.19 0.85 1.88
82 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
83 INT25332 Positive_regulation of Binding of Trh 3 0.50 0.08 1.84
84 INT16284 Negative_regulation of Negative_regulation of Trh 5 0.43 0.39 1.75
85 INT74088 Negative_regulation of Positive_regulation of Htr2c 1 0.41 0 1.75
86 INT197209 Positive_regulation of Positive_regulation of Grik1 4 0.50 0.36 1.74
87 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
88 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
89 INT30683 Binding of TRH 4 0.36 0.96 1.55
90 INT131968 Transcription of Grik1 3 0.51 1.44 1.51
91 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
92 INT168537 Negative_regulation of Gene_expression of Grik1 3 0.57 0.11 1.44
93 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
94 INT23764 Regulation of Localization of TRH 4 0.45 0.75 1.4
95 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
96 INT197224 Negative_regulation of Localization of Grik1 2 0.37 0 1.29
97 INT948 Negative_regulation of Regulation of TRH 3 0.42 0.74 1.28
98 INT272340 Transcription of Htr2c 1 0.52 2.77 1.28
99 INT19999 Regulation of Positive_regulation of Trh 5 0.44 0.15 1.26
100 INT11242 Transcription of TRH 1 0.14 0 1.24
101 INT31647 Negative_regulation of Gene_expression of Trh 5 0.43 1.07 1.22
102 INT114200 Negative_regulation of Gene_expression of Slc6a1 1 0.38 0.41 1.18
103 INT125676 Positive_regulation of Phosphorylation of Grik1 1 0.01 0 1.17
104 INT17918 Regulation of Regulation of Trh 4 0.45 1.37 1.11
105 INT95312 Regulation of Slc6a1 3 0.27 0.77 1.09
106 INT147712 Regulation of Negative_regulation of Slc6a1 1 0.45 0 1.07
107 INT168784 Regulation of Positive_regulation of Slc6a1 1 0.45 0.87 1.01
108 INT13808 Negative_regulation of Regulation of Trh 3 0.43 0.18 1
109 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
110 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
111 INT106941 Positive_regulation of Negative_regulation of Slc6a1 1 0.15 0.28 0.94
112 INT201276 Negative_regulation of Positive_regulation of Grik1 1 0.34 0.3 0.89
113 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
114 INT43998 Regulation of Gene_expression of TRH 1 0.44 0.32 0.83
115 INT271589 Regulation of Transcription of P2rx7 1 0.05 0.5 0.78
116 INT89109 Regulation of Transcription of Trh 2 0.45 1.98 0.74
117 INT42320 Positive_regulation of Regulation of Trh 1 0.50 0.15 0.74
118 INT197222 Regulation of Localization of Grik1 1 0.39 0 0.72
119 INT197206 Regulation of Gene_expression of Grik1 2 0.39 0.13 0.71
120 INT125261 Positive_regulation of Gene_expression of Htr2c 2 0.67 2.22 0.7
121 INT158836 Positive_regulation of Localization of TRH 7 0.49 2.61 0.67
122 INT125734 Negative_regulation of Transcription of P2rx7 1 0.38 0.81 0.67
123 INT272356 Positive_regulation of Transcription of Htr2c 1 0.45 1.66 0.63
124 INT185485 Negative_regulation of Localization of P2rx7 1 0.26 0.95 0.62
125 INT59532 Negative_regulation of Transcription of Trh 2 0.18 0.4 0.59
126 INT125675 Phosphorylation of Grik1 1 0.01 0 0.59
127 INT125677 Negative_regulation of Phosphorylation of Grik1 1 0.01 0 0.59
128 INT100754 Negative_regulation of Binding of Htr2c 1 0.41 0.49 0.57
129 INT196794 Regulation of Phosphorylation of Trh 1 0.04 0 0.51
130 INT153099 Negative_regulation of Positive_regulation of P2rx7 1 0.42 0.25 0.5
131 INT230986 Positive_regulation of Transcription of Htr2c 1 0.45 0.25 0.49
132 INT215732 Negative_regulation of Binding of P2rx7 1 0.11 0.74 0.49
133 INT174055 Negative_regulation of Htr2c 5 0.41 2.63 0.45
134 INT278114 Negative_regulation of Negative_regulation of P2rx7 1 0.21 0 0.45
135 INT215741 Positive_regulation of Transcription of P2rx7 1 0.15 1.15 0.43
136 INT25158 Regulation of Regulation of TRH 1 0.42 0 0.42
137 INT203495 Positive_regulation of Slc6a1 1 0.67 0.35 0.37
138 INT77495 Protein_catabolism of TRH 1 0.65 0 0.35
139 INT44364 Protein_catabolism of Trh 1 0.66 0.34 0.34
140 INT197217 Binding of Grik1 1 0.37 0.09 0.34
141 INT211023 Positive_regulation of Gene_expression of Htr2c 2 0.45 2.03 0.33
142 INT121239 Regulation of Positive_regulation of P2rx7 2 0.61 1.32 0.32
143 INT216937 Regulation of Binding of P2rx7 1 0.44 0.08 0.29
144 INT27047 Protein_catabolism of Trh 5 0.91 0.06 0.26
145 INT43253 Positive_regulation of Localization of Trh 1 0.17 0.58 0.25
146 INT211029 Negative_regulation of Gene_expression of Htr2c 1 0.56 2.54 0.25
147 INT216938 Negative_regulation of Localization of P2rx7 1 0.37 0.25 0.24
148 INT197208 Positive_regulation of Localization of Grik1 1 0.50 0.1 0.22
149 INT216940 Negative_regulation of Binding of P2rx7 1 0.37 0.15 0.2
150 INT174049 Positive_regulation of Negative_regulation of Htr2c 1 0.01 0 0.19
151 INT216889 Phosphorylation of P2rx7 1 0.23 0 0.18
152 INT174053 Phosphorylation of Htr2c 1 0.01 0.06 0.18
153 INT232448 Positive_regulation of Gene_expression of TRH 1 0.32 0.08 0.17
154 INT307467 Regulation of Binding of P2rx7 1 0.08 0 0.16
155 INT11792 Negative_regulation of Localization of TRH 1 0.28 0 0.16
156 INT270813 Positive_regulation of Localization of P2rx7 1 0.46 0.24 0.15
157 INT39203 Positive_regulation of Negative_regulation of TRH 2 0.49 1.08 0.14
158 INT272355 Regulation of Regulation of Htr2c 1 0.44 1.1 0.14
159 INT282833 Regulation of Binding of TRH 1 0.22 0.13 0.11
160 INT307481 Phosphorylation of P2rx7 1 0.15 0.35 0.08
161 INT307480 Positive_regulation of Phosphorylation of P2rx7 1 0.09 0.35 0.08
162 INT214094 Regulation of Localization of Trh 1 0.12 0.2 0.08
163 INT174050 Binding of Htr2c 1 0.01 0 0.06
164 INT211025 Regulation of Gene_expression of Htr2c 1 0.43 1.01 0.06
165 INT95316 Positive_regulation of Gene_expression of Slc6a1 1 0.51 0 0.05
166 INT70640 Positive_regulation of Protein_catabolism of Trh 1 0.34 0.06 0.03
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