GO:0014057

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Name positive regulation of acetylcholine secretion
Categary Process
Go Slim No
Go Link GO:0014057
Unique Molecular Interactions 27
Total Molecular Interactions 33
Total Single Events 480
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of acetylcholine secretion. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of acetylcholine secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT60208 Binding of Htr1a and Htr2c 2 0.52 0.25 1
2 INT140280 Negative_regulation of Binding of Adora2a and Grina 1 0.21 0.64 0.82
3 INT140281 Binding of Adora2a and Grina 1 0.19 0.64 0.82
4 INT72017 Binding of Adora2a and Ptprg 2 0.07 0 0.77
5 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
6 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
7 INT82040 Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.11 0 0.75
8 INT82041 Positive_regulation of Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.12 0 0.72
9 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
10 INT239501 Binding of Adora2a and Mtx1 1 0.24 0.95 0.64
11 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55
12 INT98726 Binding of Msr1 and Tacr2 1 0.00 0.06 0.42
13 INT89666 Binding of Adora2a and Drd2 1 0.54 0.4 0.42
14 INT302871 Negative_regulation of Adora2a Positive_regulation of Phosphorylation of Th 1 0.26 0.12 0.4
15 INT239503 Binding of Adora2a and Aes 1 0.24 0.85 0.35
16 INT115162 Adora2a Regulation of Gene_expression of Jun 1 0.49 0.36 0.34
17 INT115161 Adora2a Regulation of Gene_expression of Cpe 1 0.04 0.36 0.33
18 INT254122 Adora2a Regulation of Aliq1 1 0.01 0.85 0.3
19 INT88555 Adora2a Negative_regulation of Vegfc 1 0.00 0.17 0.25
20 INT278581 Tacr2 Positive_regulation of Tacr1 1 0.55 0 0.24
21 INT224130 Positive_regulation of Adora2a Positive_regulation of ADCY1 1 0.01 0.11 0.22
22 INT224087 Adrbk1 Negative_regulation of Adora2a 1 0.10 0.13 0.22
23 INT72015 Binding of Adora2a and Gnai2 1 0.01 0 0.21
24 INT224094 Adrbk1 Regulation of Negative_regulation of Adora2a 1 0.06 0 0.17
25 INT224129 Binding of DRD2 and Adora2a 1 0.03 0.19 0.14
26 INT174093 Htr2c Regulation of Gene_expression of Csf2 1 0.00 0 0.09
27 INT174070 Htr2c Positive_regulation of Itpr3 1 0.00 0 0.09

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of acetylcholine secretion. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of acetylcholine secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24
2 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78
3 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75
4 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47
5 INT18001 Positive_regulation of Htr2c 21 0.67 7.63 11.39
6 INT56775 Binding of Htr2c 16 0.47 3.77 8.74
7 INT23209 Binding of Adora2a 17 0.38 2.04 8.35
8 INT9032 Regulation of Htr2c 11 0.60 2.77 7.81
9 INT54755 Negative_regulation of Adora2a 17 0.58 2.7 7.75
10 INT49477 Gene_expression of Htr2c 12 0.75 3.26 5.73
11 INT83014 Binding of Adora2a 13 0.48 5.57 5.33
12 INT89664 Negative_regulation of Adora2a 11 0.59 7.81 5.07
13 INT51468 Regulation of Adora2a 8 0.48 1.5 4.84
14 INT52402 Negative_regulation of Htr2c 7 0.42 1.46 4.21
15 INT50228 Positive_regulation of Positive_regulation of Adora2a 8 0.39 0.1 4
16 INT101701 Regulation of Adora2a 8 0.45 2.3 3.63
17 INT63621 Transcription of Htr2c 6 0.52 0.62 3.49
18 INT55236 Regulation of Htr2c 6 0.44 3.31 3.36
19 INT8712 Regulation of Tacr2 5 0.45 0.53 3.02
20 INT65000 Positive_regulation of Positive_regulation of Htr2c 4 0.67 0.69 2.8
21 INT254118 Negative_regulation of Gene_expression of Adora2a 3 0.42 2.54 2.43
22 INT147525 Gene_expression of Tacr2 4 0.37 2.34 2.35
23 INT183167 Positive_regulation of Gene_expression of Adora2a 4 0.70 2.37 2.31
24 INT77309 Positive_regulation of Htr2c 3 0.49 2.72 2.25
25 INT64505 Localization of Htr2c 3 0.78 0.87 2.24
26 INT69020 Gene_expression of Htr2c 9 0.74 6.09 2.22
27 INT57939 Negative_regulation of Gene_expression of Adora2a 4 0.36 0.15 2.02
28 INT72785 Positive_regulation of Positive_regulation of Adora2a 2 0.10 1.34 1.96
29 INT194847 Negative_regulation of Positive_regulation of Adora2a 3 0.32 4.52 1.88
30 INT75177 Negative_regulation of Tacr2 3 0.08 1.05 1.83
31 INT74088 Negative_regulation of Positive_regulation of Htr2c 1 0.41 0 1.75
32 INT124337 Gene_expression of Tacr2 4 0.66 0.57 1.68
33 INT76496 Localization of Adora2a 3 0.48 0.3 1.54
34 INT48773 Binding of Tacr2 5 0.46 1.22 1.53
35 INT159978 Regulation of Gene_expression of Tacr2 1 0.29 1.24 1.49
36 INT8812 Localization of Tacr2 2 0.29 0.33 1.39
37 INT272340 Transcription of Htr2c 1 0.52 2.77 1.28
38 INT48289 Regulation of Tacr2 4 0.60 0.35 1.2
39 INT91595 Regulation of Gene_expression of Adora2a 1 0.52 0 1.19
40 INT5805 Positive_regulation of Tacr2 5 0.66 0.24 1
41 INT52090 Transcription of Adora2a 3 0.41 0.33 0.96
42 INT72006 Positive_regulation of Negative_regulation of Adora2a 2 0.40 0.26 0.94
43 INT302869 Phosphorylation of Adora2a 1 0.49 0.25 0.78
44 INT302868 Positive_regulation of Phosphorylation of Adora2a 1 0.41 0.25 0.78
45 INT80147 Negative_regulation of Binding of Adora2a 2 0.43 0.15 0.77
46 INT89663 Localization of Adora2a 1 0.74 0.74 0.75
47 INT194852 Protein_catabolism of Adora2a 1 0.56 0.6 0.75
48 INT125261 Positive_regulation of Gene_expression of Htr2c 2 0.67 2.22 0.7
49 INT224109 Phosphorylation of Adora2a 1 0.52 0.07 0.69
50 INT272356 Positive_regulation of Transcription of Htr2c 1 0.45 1.66 0.63
51 INT215637 Regulation of Regulation of Adora2a 1 0.14 0.16 0.61
52 INT141458 Regulation of Gene_expression of Adora2a 2 0.45 0.67 0.57
53 INT100754 Negative_regulation of Binding of Htr2c 1 0.41 0.49 0.57
54 INT215639 Positive_regulation of Binding of Adora2a 1 0.24 0.24 0.55
55 INT224106 Regulation of Negative_regulation of Adora2a 1 0.17 0.26 0.51
56 INT230986 Positive_regulation of Transcription of Htr2c 1 0.45 0.25 0.49
57 INT224107 Negative_regulation of Negative_regulation of Adora2a 1 0.28 0.32 0.48
58 INT174055 Negative_regulation of Htr2c 5 0.41 2.63 0.45
59 INT72143 Regulation of Binding of Adora2a 1 0.17 0 0.45
60 INT137942 Negative_regulation of Gene_expression of Tacr2 2 0.37 0.13 0.44
61 INT102385 Regulation of Transcription of Adora2a 1 0.21 0.09 0.4
62 INT102387 Negative_regulation of Transcription of Adora2a 1 0.09 0.24 0.37
63 INT211023 Positive_regulation of Gene_expression of Htr2c 2 0.45 2.03 0.33
64 INT137941 Negative_regulation of Tacr2 1 0.04 0 0.32
65 INT221765 Positive_regulation of Gene_expression of Adora2a 2 0.49 0.2 0.27
66 INT224108 Positive_regulation of Localization of Adora2a 1 0.32 0.14 0.27
67 INT224114 Regulation of Localization of Adora2a 1 0.29 0.14 0.27
68 INT211029 Negative_regulation of Gene_expression of Htr2c 1 0.56 2.54 0.25
69 INT48344 Regulation of Regulation of Tacr2 1 0.06 0 0.25
70 INT61896 Negative_regulation of Binding of Tacr2 1 0.56 0.53 0.23
71 INT224117 Negative_regulation of Positive_regulation of Adora2a 1 0.27 0.11 0.22
72 INT224105 Regulation of Phosphorylation of Adora2a 1 0.17 0 0.21
73 INT174049 Positive_regulation of Negative_regulation of Htr2c 1 0.01 0 0.19
74 INT174053 Phosphorylation of Htr2c 1 0.01 0.06 0.18
75 INT224115 Positive_regulation of Phosphorylation of Adora2a 1 0.32 0 0.16
76 INT224103 Negative_regulation of Phosphorylation of Adora2a 1 0.27 0 0.16
77 INT272355 Regulation of Regulation of Htr2c 1 0.44 1.1 0.14
78 INT278566 Transcription of Tacr2 1 0.70 0.11 0.13
79 INT278563 Regulation of Gene_expression of Tacr2 1 0.38 0.13 0.12
80 INT241728 Regulation of Transcription of Adora2a 1 0.42 0.27 0.07
81 INT241725 Transcription of Adora2a 1 0.67 0.27 0.07
82 INT174050 Binding of Htr2c 1 0.01 0 0.06
83 INT211025 Regulation of Gene_expression of Htr2c 1 0.43 1.01 0.06
84 INT147526 Positive_regulation of Gene_expression of Tacr2 1 0.01 0.3 0
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