GO:0014068

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Name positive regulation of phosphatidylinositol 3-kinase cascade
Categary Process
Go Slim No
Go Link GO:0014068
Unique Molecular Interactions 2334
Total Molecular Interactions 3599
Total Single Events 33277
Pain Genes Associated 86

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of phosphatidylinositol 3-kinase cascade. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of phosphatidylinositol 3-kinase cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2
2 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21
3 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
4 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
5 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
6 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71
7 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08
8 INT11248 Gh Positive_regulation of Ghrh 2 0.26 0.09 4.04
9 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72
10 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
11 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
12 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
13 INT13729 GHRH Positive_regulation of Localization of GH1 13 0.62 0.59 3.2
14 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
15 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
16 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
17 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
18 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
19 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
20 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 0.12 0 2.53
21 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
22 INT20411 Ghrh Positive_regulation of Gh1 6 0.56 0.62 2.47
23 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
24 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37
25 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
26 INT7367 Ghrh Regulation of Localization of Gh1 5 0.49 1.55 2.25
27 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25
28 INT9180 Ghrh Regulation of Localization of Gh 3 0.24 0.25 2.18
29 INT229394 TPSD1 Positive_regulation of F2RL1 2 0.00 3.11 2.14
30 INT3576 Sst Negative_regulation of Localization of Gh1 6 0.23 0 2.13
31 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
32 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
33 INT26948 Pomc Positive_regulation of Localization of Gh1 2 0.22 0.15 1.99
34 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
35 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
36 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
37 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
38 INT16891 GHRH Regulation of GH1 5 0.37 1.94 1.82
39 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
40 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
41 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
42 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
43 INT40827 Sstr1 Negative_regulation of Localization of Gh1 1 0.13 0 1.58
44 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
45 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
46 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
47 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42
48 INT34834 Ghrh Positive_regulation of Gene_expression of Gh1 2 0.65 0 1.4
49 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
50 INT26893 OGG1 Negative_regulation of Gh1 1 0.12 0 1.37
51 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
52 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
53 INT52568 HTR1D Regulation of Localization of Gh 2 0.20 0.16 1.34
54 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
55 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
56 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 0.07 0 1.3
57 INT107858 PRSS1 Positive_regulation of F2RL1 6 0.12 4.23 1.29
58 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
59 INT48117 GH1 Positive_regulation of CGA 1 0.10 0 1.28
60 INT162482 Binding of Agt and Vta1 1 0.23 0 1.27
61 INT42580 CAT Negative_regulation of POMC 1 0.20 0.42 1.26
62 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
63 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
64 INT162165 WDTC1 Positive_regulation of PLD2 1 0.50 0 1.25
65 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
66 INT74467 Adcyap1 Positive_regulation of Localization of Gh1 1 0.37 0 1.25
67 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
68 INT70570 su Positive_regulation of Gh 1 0.01 0.15 1.24
69 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
70 INT181490 Tryptase Positive_regulation of F2rl1 1 0.13 1.83 1.21
71 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
72 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
73 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
74 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
75 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
76 INT32480 Gh1 Positive_regulation of Gene_expression of Ghrh 1 0.35 0 1.15
77 INT14199 GNRH1 Positive_regulation of Localization of Gh1 2 0.05 0 1.12
78 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11
79 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
80 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
81 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
82 INT19887 GHRH Positive_regulation of Positive_regulation of GH1 2 0.56 0.3 1.08
83 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08
84 INT33338 Adarb1 Positive_regulation of Localization of Gh1 1 0.04 0 1.08
85 INT156238 Binding of F2rl1 and Tnfsf14 1 0.08 2.85 1.08
86 INT33336 Adarb1 Positive_regulation of Negative_regulation of Gh1 1 0.03 0 1.08
87 INT33337 Adarb1 Positive_regulation of Gh1 1 0.03 0 1.08
88 INT56990 Cat Regulation of Efs 1 0.26 0 1.05
89 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04
90 INT106345 Igf1 Regulation of Localization of Acot1 1 0.06 0 1.02
91 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
92 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
93 INT35157 GH1 Regulation of GHRH 3 0.17 0.5 0.99
94 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
95 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98
96 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
97 INT41658 IL31RA Regulation of GH1 1 0.09 1.07 0.98
98 INT19758 Ghrh Positive_regulation of Positive_regulation of Gh 1 0.26 0 0.98
99 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
100 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98
101 INT137920 Binding of Kdr and Oprm1 1 0.23 0 0.97
102 INT40424 CCK Regulation of Localization of INS 1 0.02 0 0.97
103 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97
104 INT140068 Binding of GH1 and Ghsr 1 0.00 0.47 0.97
105 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
106 INT36682 Gh1 Regulation of Gene_expression of Gnrhr 2 0.08 0 0.96
107 INT36683 Gh1 Regulation of Gnrhr 3 0.08 1.25 0.95
108 INT31108 Ghrh Negative_regulation of Gh1 2 0.55 0 0.95
109 INT62106 Ghrh Negative_regulation of Localization of Gh 1 0.06 0 0.94
110 INT62109 SLC25A4 Negative_regulation of Localization of Gh 1 0.06 0 0.94
111 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93
112 INT35252 Gene_expression of Ghrh Positive_regulation of Localization of Gh1 1 0.49 0 0.93
113 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
114 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92
115 INT207149 Binding of F2r and Par2 1 0.17 1.64 0.92
116 INT138602 Negative_regulation of BCL2L2 Positive_regulation of F2 1 0.00 0.67 0.92
117 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
118 INT138601 BCL2L2 Positive_regulation of F2 1 0.00 0.66 0.91
119 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
120 INT61587 Agt Negative_regulation of REN 1 0.00 0.42 0.91
121 INT39201 Olr824 Positive_regulation of Localization of Gh1 1 0.03 0 0.91
122 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91
123 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9
124 INT48113 GH1 Positive_regulation of Localization of CGA 1 0.07 0 0.9
125 INT30411 Ghrh Regulation of Gene_expression of Gh1 1 0.40 0.12 0.9
126 INT35160 GH1 Regulation of PRL 2 0.37 0 0.89
127 INT61046 Oprm1 Positive_regulation of Gh1 1 0.21 0 0.89
128 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 0.29 0 0.89
129 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
130 INT126268 Tpsab1 Positive_regulation of F2rl1 2 0.35 1.65 0.88
131 INT28655 Calca Negative_regulation of Localization of Gh1 1 0.34 0 0.88
132 INT44589 Negative_regulation of Oprl1 Positive_regulation of Gh1 1 0.22 0.53 0.87
133 INT298289 Runx1 Negative_regulation of Ntrk2 1 0.60 1.09 0.87
134 INT44590 Oprl1 Positive_regulation of Gh1 1 0.23 0.53 0.87
135 INT40742 Pomc Regulation of Localization of Gh1 1 0.37 0 0.86
136 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85
137 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84
138 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
139 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84
140 INT69424 Binding of Agt and Oprd1 1 0.14 0 0.84
141 INT105970 GH1 Regulation of Ghsr 1 0.04 1.16 0.84
142 INT28654 Calca Regulation of Localization of Gh1 1 0.36 0 0.84
143 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
144 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82
145 INT5103 Gal Regulation of Localization of Gh1 1 0.33 0.08 0.82
146 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
147 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
148 INT54260 SST Regulation of GH1 1 0.18 0.06 0.81
149 INT90382 Binding of CRH and GH1 1 0.34 0.05 0.81
150 INT156239 Tnfsf14 Positive_regulation of F2rl1 1 0.09 2.4 0.81
151 INT90381 Binding of GH1 and LAMC2 1 0.34 0.05 0.81
152 INT124292 Binding of Trpv1 and F2rl1 1 0.46 1.1 0.81
153 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
154 INT73775 Binding of GH1 and GHR 4 0.35 0.68 0.8
155 INT131463 NTRK1 Regulation of Localization of INS 1 0.41 0.63 0.8
156 INT40743 Binding of Gh1 and Pomc 1 0.22 0 0.8
157 INT245564 Runx3 Negative_regulation of Ntrk2 3 0.61 1.61 0.79
158 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79
159 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79
160 INT47143 Negative_regulation of Agt Positive_regulation of Avp 1 0.22 0 0.79
161 INT107739 Prkcg Negative_regulation of Positive_regulation of Pld2 1 0.46 0 0.79
162 INT105250 Cyb5b Regulation of Localization of Gh1 1 0.00 0 0.79
163 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78
164 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78
165 INT92793 Gh Positive_regulation of CTS 1 0.04 1.39 0.78
166 INT168457 Sult1a1 Positive_regulation of Cat 1 0.15 1.56 0.78
167 INT142208 Adcyap1 Positive_regulation of Transcription of Gh 1 0.05 0 0.77
168 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
169 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77
170 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
171 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
172 INT142210 Adcyap1 Positive_regulation of Gh 1 0.05 0 0.77
173 INT224463 TPSAB1 Positive_regulation of F2RL1 2 0.03 1.49 0.76
174 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
175 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
176 INT64067 Tp63 Negative_regulation of Localization of Gh1 1 0.08 0.07 0.76
177 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
178 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
179 INT152429 Ghrh Positive_regulation of Localization of Gh 4 0.37 0.56 0.75
180 INT73776 Regulation of Binding of GH1 and GHR 2 0.26 0.16 0.75
181 INT222528 Abat Positive_regulation of Gene_expression of Gh1 1 0.01 0 0.75
182 INT54802 SST Negative_regulation of Localization of Gh 1 0.01 0 0.75
183 INT54801 SST Negative_regulation of Positive_regulation of Gh 1 0.01 0 0.75
184 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
185 INT41165 Gtf3a Regulation of INS 1 0.00 0.15 0.74
186 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
187 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
188 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
189 INT17528 Prl Regulation of Gh 2 0.28 1.28 0.73
190 INT39095 Negative_regulation of Agt Positive_regulation of Localization of Ren 1 0.38 0 0.73
191 INT41164 Binding of INS and SST 1 0.07 0.14 0.73
192 INT31643 POMC Regulation of INS 1 0.59 0.62 0.73
193 INT106999 F2 Positive_regulation of PAR4 3 0.06 1.83 0.72
194 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
195 INT16894 Regulation of GHRH Regulation of GH1 2 0.37 0 0.72
196 INT14196 Glra2 Positive_regulation of Localization of Gh1 1 0.06 0 0.71
197 INT338057 Positive_regulation of F2r Positive_regulation of Localization of Calca 1 0.05 0.28 0.71
198 INT31307 Ghrh Regulation of Gh1 3 0.27 1.36 0.7
199 INT30125 Binding of Gh and Ghrh 2 0.06 0.36 0.7
200 INT341534 INSRR Positive_regulation of F2RL1 1 0.00 1.4 0.7

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of phosphatidylinositol 3-kinase cascade. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of phosphatidylinositol 3-kinase cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT876 Localization of Gh1 843 0.80 67.75 340.82
2 INT1893 Localization of Gh 1041 0.79 340.23 256.58
3 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18
4 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23
5 INT812 Localization of INS 1026 0.81 515.6 145.31
6 INT252 Localization of GH1 529 0.80 227.4 122.05
7 INT1530 Regulation of Gh 382 0.61 115.96 112.47
8 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
9 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98
10 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5
11 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97
12 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91
13 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16
14 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28
15 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71
16 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
17 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45
18 INT1782 Regulation of Gh1 125 0.62 22 55.74
19 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
20 INT251 Regulation of INS 398 0.62 232.47 55.04
21 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77
22 INT921 Regulation of GH1 172 0.60 52.88 51.04
23 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
24 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75
25 INT531 Gene_expression of GH1 376 0.75 193.45 46.24
26 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
27 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56
28 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68
29 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
30 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
31 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
32 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
33 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
34 INT255 Regulation of Localization of GH1 89 0.62 18.71 35.3
35 INT100733 Positive_regulation of F2RL1 62 0.70 59.14 35.22
36 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
37 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
38 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92
39 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
40 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39
41 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
42 INT1158 Regulation of Agt 106 0.61 29.4 30.29
43 INT94658 Positive_regulation of F2rl1 51 0.70 33.65 27.46
44 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
45 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01
46 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
47 INT16721 Negative_regulation of Cat 56 0.59 44.44 22.84
48 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
49 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15
50 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
51 INT90849 Gene_expression of F2rl1 55 0.78 31.31 20.65
52 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61
53 INT78901 Localization of CCL5 67 0.78 40.79 20.59
54 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59
55 INT100732 Gene_expression of F2RL1 55 0.78 38.89 19.45
56 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
57 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
58 INT13454 Positive_regulation of Positive_regulation of Gh 49 0.68 14.53 18.49
59 INT118512 Gene_expression of F2r 33 0.63 26.56 18.26
60 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04
61 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23
62 INT10841 Positive_regulation of Gene_expression of Gh 101 0.59 45.39 16.96
63 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
64 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
65 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
66 INT2066 Localization of Agt 56 0.80 9.95 16.25
67 INT12950 Gene_expression of Cat 85 0.75 35.94 15.76
68 INT4242 Negative_regulation of Positive_regulation of Gh1 26 0.58 1.47 15.75
69 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46
70 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
71 INT104674 Positive_regulation of F2rl1 35 0.65 27.76 14.16
72 INT14572 Binding of INS 205 0.48 175.43 13.38
73 INT4298 Positive_regulation of Positive_regulation of Gh1 30 0.50 1.79 13.32
74 INT65172 Negative_regulation of Ntrk2 35 0.59 9.89 13.08
75 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
76 INT3962 Regulation of AGT 50 0.62 20.96 13.01
77 INT9678 Positive_regulation of Positive_regulation of GH1 32 0.68 8.14 12.97
78 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83
79 INT4199 Binding of Agt 76 0.48 21.06 12.66
80 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
81 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
82 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64
83 INT398 Localization of AGT 45 0.78 16.97 11.54
84 INT8065 Binding of AGT 54 0.48 20.54 10.85
85 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83
86 INT4498 Gene_expression of F2 83 0.65 57.4 10.8
87 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75
88 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67
89 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
90 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
91 INT79720 Positive_regulation of Cat 57 0.70 31.81 10.11
92 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09
93 INT120509 Gene_expression of Cat 65 0.77 50.9 9.75
94 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
95 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
96 INT11510 Negative_regulation of Positive_regulation of Gh 28 0.52 12.71 9.16
97 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95
98 INT6499 Localization of Ntrk2 44 0.79 11.78 8.75
99 INT386 Positive_regulation of Gene_expression of Agt 37 0.70 15.92 8.73
100 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66
101 INT34777 Localization of IGF1 82 0.80 42.68 8.62
102 INT47682 Transcription of Ntrk2 19 0.69 6.32 8.6
103 INT8423 Gene_expression of Cntf 29 0.69 11.69 8.4
104 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
105 INT15592 Positive_regulation of F2r 17 0.67 8.66 8.36
106 INT12292 Negative_regulation of Positive_regulation of GH1 22 0.58 5.02 8.28
107 INT117497 Positive_regulation of F2r 18 0.57 14.45 8.13
108 INT18736 Gene_expression of Ptpn6 19 0.59 4.44 8.06
109 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98
110 INT2271 Gene_expression of F2 51 0.76 30.21 7.97
111 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86
112 INT48314 Gene_expression of NTRK2 17 0.75 7.84 7.83
113 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8
114 INT76892 Gene_expression of FGFR1 45 0.69 23.6 7.56
115 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53
116 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51
117 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41
118 INT103791 Positive_regulation of Positive_regulation of F2rl1 10 0.50 11.24 7.41
119 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39
120 INT9491 Positive_regulation of Ptpn6 11 0.51 2.33 7.32
121 INT4299 Positive_regulation of Gene_expression of Gh1 27 0.50 5.24 7.31
122 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27
123 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18
124 INT717 Regulation of F2 29 0.61 17.46 6.99
125 INT878 Regulation of Gene_expression of Gh1 13 0.43 1.13 6.98
126 INT47691 Positive_regulation of Gene_expression of Ntrk2 17 0.62 13.64 6.96
127 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
128 INT181348 Localization of Ccl5 24 0.65 19.55 6.8
129 INT142344 Transcription of Igf1 22 0.69 7.55 6.77
130 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75
131 INT61114 Gene_expression of Ppard 23 0.75 14.98 6.62
132 INT107737 Positive_regulation of Pld2 11 0.67 0.33 6.45
133 INT134290 Positive_regulation of PLD2 10 0.68 3.06 6.44
134 INT28861 Binding of Gh 61 0.46 25.61 6.38
135 INT64052 Positive_regulation of FGFR1 26 0.52 28.47 6.36
136 INT118516 Positive_regulation of Positive_regulation of F2RL1 7 0.49 4.63 6.33
137 INT47681 Regulation of Ntrk2 17 0.62 3.61 6.31
138 INT14560 Regulation of Igf1 41 0.59 19.59 6.3
139 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26
140 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
141 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1
142 INT9321 Transcription of Igf1 25 0.69 10.2 6.08
143 INT9683 Binding of GH1 57 0.47 21.14 5.99
144 INT10843 Regulation of Regulation of Gh 14 0.22 5.56 5.93
145 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86
146 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84
147 INT8916 Regulation of Igf1 45 0.60 13.06 5.81
148 INT3614 Negative_regulation of Gene_expression of Gh1 16 0.42 6.8 5.74
149 INT111384 Gene_expression of Adora3 18 0.75 10.53 5.73
150 INT151032 Localization of Igf1 49 0.76 26.32 5.71
151 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
152 INT50975 Localization of Ptpn6 8 0.65 2.64 5.7
153 INT22839 Gene_expression of F2 31 0.74 15.53 5.56
154 INT106552 Positive_regulation of Gene_expression of Ntrk2 19 0.68 9.72 5.51
155 INT13735 Negative_regulation of Regulation of GH1 14 0.42 4.35 5.39
156 INT35536 Negative_regulation of CAT 26 0.57 14.39 5.38
157 INT213741 Gene_expression of Kdr 60 0.75 44.24 5.35
158 INT38366 Regulation of Cat 45 0.62 23.45 5.34
159 INT96778 Positive_regulation of Pdgfa 22 0.46 12.7 5.31
160 INT107103 Negative_regulation of Ntrk2 21 0.59 10.38 5.28
161 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23
162 INT120511 Positive_regulation of Gene_expression of Cat 26 0.69 19.82 5.2
163 INT90848 Localization of F2rl1 23 0.80 3.15 5.2
164 INT181363 Regulation of Ccl5 16 0.46 13.65 5.09
165 INT20650 Positive_regulation of F2 26 0.69 15.49 5.08
166 INT106555 Binding of Ntrk2 15 0.48 6.31 5.05
167 INT4611 Transcription of Gh1 12 0.68 1.04 4.97
168 INT181362 Negative_regulation of Ccl5 21 0.40 15.63 4.96
169 INT82887 Positive_regulation of Ccl5 10 0.40 3.4 4.91
170 INT105256 Positive_regulation of Gene_expression of F2rl1 6 0.68 10.09 4.83
171 INT176614 Positive_regulation of Gene_expression of Ccl5 20 0.59 16.2 4.81
172 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
173 INT89590 Negative_regulation of Gene_expression of Ccl5 8 0.36 3.97 4.67
174 INT90852 Gene_expression of F2r 26 0.78 5.5 4.66
175 INT4378 Regulation of Gene_expression of GH1 26 0.47 10.2 4.61
176 INT97903 Negative_regulation of FGFR1 16 0.17 5.6 4.57
177 INT181042 Binding of Ccl5 18 0.41 9.34 4.51
178 INT115805 Gene_expression of PLD2 7 0.76 12.49 4.51
179 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45
180 INT9842 Binding of F2 36 0.47 22.79 4.42
181 INT65056 Binding of Ntrk2 20 0.36 3.72 4.42
182 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
183 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38
184 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
185 INT16220 Negative_regulation of Regulation of Gh 13 0.42 3.59 4.33
186 INT28734 Gene_expression of Reln 7 0.74 5.76 4.33
187 INT122882 Regulation of Ntrk2 13 0.62 9.7 4.3
188 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
189 INT49360 Localization of Igf1 22 0.76 6.96 4.26
190 INT4239 Negative_regulation of CCL5 15 0.40 10.92 4.26
191 INT47686 Regulation of Gene_expression of Ntrk2 5 0.44 5.24 4.14
192 INT144428 Positive_regulation of Gene_expression of Erbb2 41 0.69 41.4 4.13
193 INT10842 Transcription of Gh 18 0.64 2.94 4.13
194 INT100372 Gene_expression of Flt1 47 0.71 24.33 4.09
195 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
196 INT200047 Negative_regulation of Gene_expression of Ntrk2 8 0.56 10.78 3.95
197 INT96776 Positive_regulation of Gene_expression of Pdgfa 8 0.40 7.79 3.93
198 INT89394 Phosphorylation of INS 37 0.82 35.84 3.9
199 INT19104 Regulation of Gene_expression of Gh 24 0.40 8.42 3.88
200 INT107860 Positive_regulation of Gene_expression of F2RL1 10 0.68 6.36 3.88
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