GO:0014732

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Name skeletal muscle atrophy
Categary Process
Go Slim No
Go Link GO:0014732
Unique Molecular Interactions 32
Total Molecular Interactions 40
Total Single Events 421
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for skeletal muscle atrophy. They are ordered first by their pain relevance and then by number of times they were reported for skeletal muscle atrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
2 INT172147 Binding of IL15 and TNF 2 0.05 1.19 0.72
3 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
4 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3
5 INT226380 Gene_expression of IL15 Negative_regulation of Positive_regulation of CD8A 1 0.02 1.59 0.18
6 INT273103 Binding of Mtor and Rps6kb1 1 0.44 0 0.11
7 INT273112 Positive_regulation of Binding of Mtor and Rps6kb1 1 0.46 0.05 0.11
8 INT313886 RPS6KB1 Positive_regulation of Gene_expression of XRCC1 1 0.01 0.8 0.05
9 INT351012 IL2RB Positive_regulation of Gene_expression of IL15 1 0.10 0.42 0.05
10 INT150048 Ins1 Positive_regulation of Rps6kb1 2 0.23 0.83 0.04
11 INT257869 Rps6kb1 Regulation of Eif4ebp1 1 0.02 0.64 0.04
12 INT257872 Eif4ebp1 Regulation of Rps6kb1 1 0.02 0.64 0.04
13 INT228679 Binding of Rps6kb1 and Fig4 1 0.08 0.08 0.04
14 INT257868 Agt Positive_regulation of Rps6kb1 1 0.10 0.37 0.04
15 INT273117 Trh Positive_regulation of Rps6kb1 1 0.01 0.09 0.04
16 INT253375 Lep Positive_regulation of Phosphorylation of Rps6kb1 1 0.41 0.16 0.03
17 INT230066 IL15 Positive_regulation of Gene_expression of KLRD1 1 0.01 0.37 0.03
18 INT253412 ATIC Negative_regulation of Rps6kb1 1 0.02 0 0.03
19 INT284311 RPS6KB1 Positive_regulation of Phosphorylation of IRS1 1 0.18 0.24 0
20 INT281609 Foxo3 Positive_regulation of Transcription of Trim63 1 0.29 0 0
21 INT188067 Rps6kb1 Regulation of Rps6 1 0.10 0.1 0
22 INT313842 Mstn Regulation of Gene_expression of Fstl3 1 0.32 0.08 0
23 INT253380 Il6 Positive_regulation of Phosphorylation of Rps6kb1 1 0.29 0.07 0
24 INT253364 Lep Positive_regulation of Rps6kb1 1 0.30 0.08 0
25 INT299628 MSTN Negative_regulation of Gene_expression of MYOD1 1 0.09 0.15 0
26 INT313840 Binding of Acvr2b and Mstn 1 0.02 0.07 0
27 INT289519 Sirt1 Regulation of Rps6kb1 1 0.25 0.13 0
28 INT281608 Foxo4 Positive_regulation of Transcription of Trim63 1 0.27 0 0
29 INT351095 Binding of FKBP1A and RPS6KB1 1 0.24 0.36 0
30 INT351101 Negative_regulation of Binding of FKBP1A and RPS6KB1 1 0.27 0.36 0
31 INT289527 Lep Regulation of Rps6kb1 1 0.10 0.07 0
32 INT281607 Foxo1 Positive_regulation of Transcription of Trim63 1 0.27 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for skeletal muscle atrophy. They are ordered first by their pain relevance and then by number of times they were reported in skeletal muscle atrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT172171 Gene_expression of IL15 47 0.37 46.23 13.41
2 INT122997 Phosphorylation of Rps6kb1 46 0.72 9.92 3.43
3 INT228677 Negative_regulation of Phosphorylation of Rps6kb1 24 0.51 3.88 2.97
4 INT226453 Positive_regulation of Gene_expression of IL15 9 0.24 12.66 2.38
5 INT181720 Regulation of IL15 9 0.20 3.65 1.79
6 INT139263 Gene_expression of Mstn 10 0.62 6.67 1.51
7 INT228670 Negative_regulation of Rps6kb1 12 0.38 5.27 1.21
8 INT103699 Negative_regulation of IL15 5 0.24 2.42 1.12
9 INT188398 Positive_regulation of IL15 8 0.19 4.64 1.06
10 INT174069 Positive_regulation of Rps6kb1 14 0.61 3.7 0.77
11 INT122999 Gene_expression of Rps6kb1 16 0.67 3.45 0.71
12 INT112465 Binding of Rps6kb1 3 0.25 1.26 0.69
13 INT258630 Binding of IL15 3 0.24 2.2 0.65
14 INT226196 Positive_regulation of Gene_expression of Mstn 3 0.54 2.68 0.46
15 INT226198 Regulation of Mstn 3 0.48 2.99 0.45
16 INT263820 Phosphorylation of RPS6KB1 6 0.52 1.43 0.42
17 INT285554 Regulation of Transcription of IL15 1 0.15 0.61 0.4
18 INT285546 Regulation of Gene_expression of IL15 1 0.15 0.61 0.4
19 INT285556 Transcription of IL15 1 0.23 0.6 0.4
20 INT235498 Localization of IL15 6 0.21 2.17 0.39
21 INT203081 Gene_expression of Trim63 2 0.56 1.53 0.39
22 INT90876 Negative_regulation of RPS6KB1 2 0.47 1.29 0.36
23 INT122996 Positive_regulation of Phosphorylation of Rps6kb1 9 0.58 1.53 0.34
24 INT281599 Localization of Rps6kb1 2 0.59 0.61 0.28
25 INT203067 Positive_regulation of Gene_expression of Trim63 2 0.50 0.92 0.28
26 INT281588 Negative_regulation of Localization of Rps6kb1 2 0.33 0.16 0.22
27 INT293351 Negative_regulation of Regulation of IL15 1 0.04 0.34 0.22
28 INT226195 Regulation of Gene_expression of Mstn 2 0.48 1.23 0.2
29 INT270722 Regulation of Positive_regulation of RPS6KB1 2 0.49 1.07 0.19
30 INT228901 Positive_regulation of RPS6KB1 5 0.55 2.44 0.18
31 INT217658 Negative_regulation of MSTN 4 0.30 1.35 0.17
32 INT257862 Negative_regulation of Positive_regulation of Rps6kb1 3 0.38 1.24 0.13
33 INT281604 Negative_regulation of Gene_expression of Trim63 1 0.42 0.65 0.13
34 INT281585 Binding of Trim63 1 0.27 0.59 0.12
35 INT46335 Regulation of Rps6kb1 8 0.40 2.39 0.11
36 INT228902 Gene_expression of RPS6KB1 5 0.75 2.32 0.1
37 INT274488 Positive_regulation of Localization of IL15 1 0.07 0.9 0.1
38 INT139262 Negative_regulation of Mstn 1 0.54 0.1 0.09
39 INT349555 Positive_regulation of Localization of Rps6kb1 1 0.39 0.45 0.09
40 INT122998 Positive_regulation of Gene_expression of Rps6kb1 2 0.60 0.62 0.08
41 INT284331 Positive_regulation of Phosphorylation of RPS6KB1 5 0.32 0.7 0.05
42 INT263818 Negative_regulation of Phosphorylation of RPS6KB1 1 0.01 0.43 0.05
43 INT281595 Regulation of Binding of Trim63 1 0.33 0.32 0.05
44 INT222291 Positive_regulation of Trim63 3 0.50 0.94 0.04
45 INT281601 Regulation of Trim63 1 0.14 0.17 0.04
46 INT281592 Regulation of Gene_expression of Trim63 1 0.33 0.17 0.04
47 INT257851 Regulation of Phosphorylation of Rps6kb1 1 0.40 0.95 0.03
48 INT217654 Gene_expression of MSTN 11 0.60 4.41 0
49 INT217659 Regulation of Gene_expression of MSTN 4 0.31 1.15 0
50 INT222292 Transcription of Trim63 3 0.52 0.32 0
51 INT217660 Regulation of MSTN 2 0.14 0.49 0
52 INT228900 Positive_regulation of Gene_expression of RPS6KB1 2 0.49 1.6 0
53 INT222294 Positive_regulation of Transcription of Trim63 2 0.36 0.17 0
54 INT281593 Regulation of Positive_regulation of Trim63 1 0.33 0 0
55 INT351115 Negative_regulation of Binding of RPS6KB1 1 0.34 0.29 0
56 INT289570 Positive_regulation of Regulation of Rps6kb1 1 0.24 0.06 0
57 INT351117 Binding of RPS6KB1 1 0.30 0.77 0
58 INT313836 Localization of Mstn 1 0.55 0.16 0
59 INT253407 Negative_regulation of Gene_expression of Rps6kb1 1 0.29 0 0
60 INT277404 Positive_regulation of MSTN 1 0.62 2.29 0
61 INT293348 Negative_regulation of Positive_regulation of IL15 1 0.04 0.12 0
62 INT281584 Regulation of Transcription of Trim63 1 0.20 0 0
63 INT281590 Negative_regulation of Trim63 1 0.31 0.08 0
64 INT351129 Regulation of RPS6KB1 1 0.36 0.15 0
65 INT217657 Negative_regulation of Gene_expression of MSTN 1 0.19 0.42 0
66 INT299634 Positive_regulation of Gene_expression of MSTN 1 0.35 0.6 0
67 INT284330 Positive_regulation of Positive_regulation of RPS6KB1 1 0.23 0.24 0
68 INT227667 Transcription of MSTN 1 0.27 0.24 0
69 INT313839 Protein_catabolism of Mstn 1 0.51 0.08 0
70 INT283374 Positive_regulation of Mstn 1 0.30 0.32 0
71 INT281586 Protein_catabolism of Trim63 1 0.47 0.06 0
72 INT257856 Positive_regulation of Positive_regulation of Rps6kb1 1 0.61 0.64 0
73 INT217655 Binding of MSTN 1 0.16 0.13 0
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