GO:0014824

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Name artery smooth muscle contraction
Categary Process
Go Slim No
Go Link GO:0014824
Unique Molecular Interactions 658
Total Molecular Interactions 947
Total Single Events 6133
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for artery smooth muscle contraction. They are ordered first by their pain relevance and then by number of times they were reported for artery smooth muscle contraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
2 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
3 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
4 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
5 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
6 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
7 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
8 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
9 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
10 INT162482 Binding of Agt and Vta1 1 0.23 0 1.27
11 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
12 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
13 INT172500 Ednra Positive_regulation of Coc 1 0.01 1 1.2
14 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
15 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
16 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
17 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
18 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97
19 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
20 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
21 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
22 INT123023 Ednra Regulation of Adarb1 1 0.00 0 0.93
23 INT123024 Csf2 Regulation of Ednra 1 0.06 0 0.92
24 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
25 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
26 INT61587 Agt Negative_regulation of REN 1 0.00 0.42 0.91
27 INT128701 Ednra Regulation of EDNRB 1 0.17 0.58 0.84
28 INT69424 Binding of Agt and Oprd1 1 0.14 0 0.84
29 INT128702 Ednra Regulation of EDNRA 1 0.00 0.58 0.84
30 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
31 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82
32 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
33 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
34 INT157918 TRPV1 Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
35 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
36 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
37 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
38 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
39 INT47143 Negative_regulation of Agt Positive_regulation of Avp 1 0.22 0 0.79
40 INT39095 Negative_regulation of Agt Positive_regulation of Localization of Ren 1 0.38 0 0.73
41 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
42 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
43 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
44 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
45 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68
46 INT141063 Agt Regulation of Agtr1a 1 0.28 1.18 0.68
47 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
48 INT134286 PLD2 Regulation of Regulation of EDNRA 1 0.10 0 0.67
49 INT47145 Penk Negative_regulation of Agt 1 0.06 0 0.66
50 INT162878 Agt Regulation of Ang 1 0.21 1.15 0.66
51 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
52 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
53 INT94020 Binding of EDN2 and INSRR 1 0.03 0 0.65
54 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64
55 INT219921 EDNRA Negative_regulation of Trpv1 1 0.13 0.36 0.63
56 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
57 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
58 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
59 INT57421 Oprd1 Regulation of Agt 1 0.29 0 0.62
60 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61
61 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6
62 INT131642 Edn1 Positive_regulation of Positive_regulation of Insrr 1 0.01 0.44 0.6
63 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
64 INT56116 Agt Positive_regulation of Lhb 1 0.15 0 0.58
65 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
66 INT56117 Agt Positive_regulation of Positive_regulation of CGA 1 0.00 0 0.56
67 INT62597 Binding of Edn1 and Vip 1 0.23 0.79 0.54
68 INT73367 Agt Negative_regulation of Localization of Calca 1 0.43 0.26 0.54
69 INT34459 AGT Negative_regulation of MBTPS1 1 0.01 0 0.54
70 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53
71 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53
72 INT130160 Pomc Regulation of Edn1 1 0.25 0 0.53
73 INT132438 Binding of AGT and OXTR 1 0.08 1.03 0.53
74 INT256019 Agt Negative_regulation of Lnpep 1 0.23 1.76 0.53
75 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
76 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
77 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49
78 INT94015 Binding of EDN1 and INSRR 1 0.04 0 0.49
79 INT94024 Binding of EDN1 and EDN3 1 0.27 0 0.49
80 INT39078 Binding of Agt and Penk 1 0.24 0.42 0.48
81 INT94018 Binding of EDN2 and EDN3 1 0.19 0 0.48
82 INT47144 Negative_regulation of Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
83 INT47146 Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
84 INT99571 Edn1 Positive_regulation of Localization of Ednra 1 0.01 0.32 0.47
85 INT39077 Agt Negative_regulation of Prss12 1 0.05 0.44 0.46
86 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
87 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
88 INT50497 Edn1 Positive_regulation of Pla2g1b 1 0.01 0.23 0.45
89 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45
90 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
91 INT151958 Negative_regulation of Agt Positive_regulation of Agtrap 1 0.39 0 0.44
92 INT94093 Pnoc Positive_regulation of EDNRA 1 0.03 0.1 0.44
93 INT151959 Agt Positive_regulation of Agtrap 1 0.63 0 0.44
94 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43
95 INT184543 Agt Positive_regulation of Ccl2 1 0.16 3.18 0.43
96 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
97 INT36459 Binding of Agt and Positive_regulation of Localization of Avp 1 0.38 0.19 0.43
98 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
99 INT313704 Smn1 Negative_regulation of Gene_expression of Edn1 1 0.32 0 0.42
100 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42
101 INT153766 Edn1 Positive_regulation of Gtf3a 1 0.04 1.25 0.41
102 INT334763 Ednra Positive_regulation of Gabrg1 1 0.01 0 0.4
103 INT36460 Binding of Agt and Avp 1 0.28 0.16 0.4
104 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
105 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
106 INT64384 Agt Negative_regulation of Son 1 0.26 0 0.39
107 INT77683 Ednra Negative_regulation of LH 1 0.03 0.23 0.39
108 INT99399 Penk Positive_regulation of Edn1 1 0.00 0 0.38
109 INT99400 Gast Positive_regulation of Edn1 1 0.00 0 0.38
110 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
111 INT173704 Binding of PCOS1 and Edn1 1 0.01 0.99 0.37
112 INT313701 Calca Negative_regulation of Binding of Edn1 1 0.30 0.14 0.37
113 INT39092 Agt Negative_regulation of Ren 1 0.39 0 0.37
114 INT80444 Binding of EDNRA and SPR 1 0.05 0.1 0.36
115 INT152314 Il18 Regulation of Edn1 1 0.02 0.22 0.36
116 INT53257 CALCRL Negative_regulation of Binding of Agt 1 0.00 0 0.36
117 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
118 INT152316 Ifng Regulation of Edn1 1 0.01 0.22 0.35
119 INT44112 Agt Regulation of Penk 1 0.08 0 0.35
120 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
121 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
122 INT4638 Binding of Agt and Adarb1 3 0.01 0 0.34
123 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34
124 INT330122 Agt Positive_regulation of Gene_expression of Agtr1a 1 0.03 0.69 0.34
125 INT330119 Agt Positive_regulation of Gene_expression of Bdkrb1 1 0.37 0.63 0.34
126 INT162157 Binding of SGCG and Agt 1 0.33 0.35 0.33
127 INT207576 RETN Positive_regulation of Gene_expression of EDN1 1 0.05 0.78 0.33
128 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
129 INT147436 Agt Positive_regulation of Gene_expression of Ros1 1 0.02 0.5 0.33
130 INT242995 Agt Positive_regulation of Spp1 1 0.36 1.82 0.33
131 INT229363 Negative_regulation of Binding of Agt and Agtr1a 2 0.22 0.9 0.32
132 INT303030 Binding of Ednra and MCPH1 1 0.00 1.02 0.32
133 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32
134 INT44127 Agt Negative_regulation of DSPP 1 0.02 0 0.32
135 INT119603 H2-Ab1 Regulation of EDNRA 1 0.00 0.07 0.32
136 INT119602 EDNRA Regulation of H2-Ab1 1 0.00 0.07 0.32
137 INT303005 Binding of Ednra and Pah 1 0.06 1.02 0.32
138 INT67266 Edn1 Negative_regulation of Ece1 1 0.19 0.17 0.32
139 INT56115 Agt Regulation of Lhb 1 0.16 0 0.32
140 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31
141 INT182262 EDN1 Positive_regulation of Gene_expression of NOS2 1 0.28 0.79 0.31
142 INT99843 Edn3 Negative_regulation of Localization of Ren 1 0.25 0.42 0.31
143 INT69365 Binding of EDNRA and Pnoc 1 0.00 0 0.31
144 INT71519 Edn1 Positive_regulation of Gene_expression of Adarb1 1 0.02 0.48 0.31
145 INT284137 EDNRB Regulation of EDNRA 1 0.07 0.09 0.3
146 INT117588 Binding of C5AR1 and EDNRA 1 0.40 0.38 0.3
147 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
148 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28
149 INT116853 Chdh Regulation of Positive_regulation of Agt 1 0.11 0.19 0.28
150 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
151 INT178102 EDNRA Positive_regulation of Localization of TIMP1 1 0.06 0.97 0.28
152 INT178088 EDNRA Positive_regulation of Transcription of TIMP1 1 0.06 0.97 0.28
153 INT54639 Edn3 Negative_regulation of Edn2 1 0.00 0 0.28
154 INT45541 Agt Positive_regulation of Lnpep 1 0.03 0 0.27
155 INT45545 Agt Positive_regulation of Oxt 1 0.23 0 0.27
156 INT72820 EDN3 Positive_regulation of Avp 1 0.31 0.64 0.27
157 INT239226 Binding of Edn1 and Ednra 2 0.06 1.59 0.26
158 INT124117 Apcs Negative_regulation of Ednra 1 0.09 0 0.26
159 INT219918 Positive_regulation of EDNRA Positive_regulation of Trpv1 1 0.13 0 0.26
160 INT126550 Agt Positive_regulation of Gene_expression of Nsfl1c 1 0.39 1.07 0.26
161 INT242991 Agt Positive_regulation of Gene_expression of Spp1 1 0.21 0.66 0.26
162 INT9528 Agt Positive_regulation of Localization of Pomc 2 0.50 0.14 0.25
163 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25
164 INT126547 Agt Positive_regulation of Nfkb1 1 0.46 0.99 0.25
165 INT126548 Negative_regulation of Agt Positive_regulation of Nfkb1 1 0.29 0.99 0.25
166 INT297258 Binding of Agt and Agtr2 1 0.23 0.7 0.25
167 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
168 INT126553 Agt Positive_regulation of Nfkb1 1 0.06 0.99 0.25
169 INT178095 EDN1 Positive_regulation of MMP3 1 0.04 0.88 0.24
170 INT178076 EDN1 Positive_regulation of MMP2 1 0.04 0.88 0.24
171 INT256028 Binding of Agt and Lnpep 1 0.19 1.16 0.24
172 INT178085 EDN1 Positive_regulation of MMP7 1 0.06 0.89 0.24
173 INT178141 EDN1 Positive_regulation of Timp1 1 0.30 0.89 0.24
174 INT41588 Binding of AGT and Lhb 1 0.00 0 0.24
175 INT36875 Binding of EDNRA and SYNCRIP 1 0.01 0 0.24
176 INT178075 EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
177 INT178104 EDN1 Positive_regulation of Localization of TIMP1 1 0.05 0.83 0.24
178 INT178094 Positive_regulation of EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
179 INT178142 EDN1 Positive_regulation of Localization of Timp1 1 0.28 0.89 0.24
180 INT41589 Binding of AGT and Prl 1 0.00 0 0.24
181 INT126551 Agt Positive_regulation of Gene_expression of Ptgs1 1 0.25 0.92 0.24
182 INT178077 EDN1 Positive_regulation of MMP9 1 0.06 0.88 0.24
183 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24
184 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23
185 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23
186 INT182272 EDN1 Regulation of Gene_expression of MMP13 1 0.26 0.87 0.22
187 INT91686 Mb Positive_regulation of Edn1 1 0.03 0.29 0.22
188 INT284139 EDNRB Positive_regulation of Gene_expression of EDNRA 1 0.12 0.45 0.22
189 INT182265 EDN1 Positive_regulation of NOS2 1 0.24 0.56 0.22
190 INT36876 EDNRA Regulation of Negative_regulation of PRB1 1 0.00 0 0.21
191 INT182263 EDN1 Positive_regulation of MMP1 1 0.15 0.43 0.21
192 INT222566 Agt Positive_regulation of Localization of Prl 1 0.08 0.23 0.21
193 INT229360 Agt Positive_regulation of Agtr1a 2 0.48 1.26 0.2
194 INT106825 Ednra Negative_regulation of Igf1 1 0.07 0.07 0.2
195 INT275159 Agt Positive_regulation of Phosphorylation of Stat3 1 0.04 1.44 0.2
196 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 0.05 0.82 0.2
197 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
198 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
199 INT249993 Binding of Agt and Igkv4-55 1 0.02 0.49 0.2
200 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19

Single Events

The table below shows the top 100 pain related interactions that have been reported for artery smooth muscle contraction. They are ordered first by their pain relevance and then by number of times they were reported in artery smooth muscle contraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
2 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
3 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
4 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
5 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
6 INT1158 Regulation of Agt 106 0.61 29.4 30.29
7 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
8 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
9 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
10 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
11 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
12 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
13 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
14 INT5048 Binding of Edn1 55 0.47 18.86 19.16
15 INT6728 Gene_expression of Ednra 43 0.65 13.41 17.38
16 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
17 INT2066 Localization of Agt 56 0.80 9.95 16.25
18 INT9191 Localization of EDN1 94 0.81 57.01 14.78
19 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
20 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
21 INT6365 Localization of Edn1 56 0.81 18.84 13.83
22 INT3962 Regulation of AGT 50 0.62 20.96 13.01
23 INT4199 Binding of Agt 76 0.48 21.06 12.66
24 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
25 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79
26 INT398 Localization of AGT 45 0.78 16.97 11.54
27 INT8065 Binding of AGT 54 0.48 20.54 10.85
28 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
29 INT6361 Localization of Edn1 30 0.81 19.09 9.7
30 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86
31 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79
32 INT386 Positive_regulation of Gene_expression of Agt 37 0.70 15.92 8.73
33 INT6727 Positive_regulation of Ednra 27 0.64 18.75 8.71
34 INT10237 Binding of EDN1 40 0.48 16 8.48
35 INT30382 Negative_regulation of Ednra 21 0.42 12.06 8.19
36 INT77804 Regulation of Ednra 9 0.39 2.71 7.94
37 INT54978 Binding of EDNRA 36 0.41 14.97 7.86
38 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
39 INT67170 Gene_expression of Ednra 22 0.65 9.35 7.57
40 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
41 INT167049 Binding of Ednra 3 0.07 3.47 6.84
42 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
43 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84
44 INT70907 Negative_regulation of EDNRA 30 0.36 19.68 5.49
45 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36
46 INT92858 Negative_regulation of Ednra 6 0.57 1.25 4.81
47 INT17803 Regulation of Edn1 14 0.54 4.75 4.71
48 INT246315 Localization of Ednra 22 0.15 2.73 4.64
49 INT21953 Binding of Ednra 12 0.33 4.72 4.56
50 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
51 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
52 INT5782 Gene_expression of Edn3 17 0.67 3.38 3.65
53 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
54 INT115203 Negative_regulation of Positive_regulation of Ednra 5 0.33 1.27 3.32
55 INT49971 Regulation of Ednra 10 0.35 2.4 3.06
56 INT55033 Localization of Edn3 7 0.80 1.4 3.05
57 INT53374 Binding of Edn1 17 0.43 11.66 2.98
58 INT93058 Positive_regulation of Gene_expression of Ednra 8 0.28 4.11 2.88
59 INT76836 Positive_regulation of Ednra 6 0.55 2.65 2.72
60 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71
61 INT17857 Negative_regulation of Gene_expression of AGT 25 0.46 21.16 2.45
62 INT148071 Gene_expression of Agt 42 0.74 44.9 2.43
63 INT4270 Negative_regulation of Negative_regulation of Agt 10 0.43 1.08 2.43
64 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27
65 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
66 INT10201 Positive_regulation of Localization of Agt 8 0.50 0.97 2.21
67 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07
68 INT12005 Negative_regulation of Localization of Agt 6 0.57 1.49 2.06
69 INT156677 Regulation of Gene_expression of Ednra 4 0.15 0.25 2.05
70 INT79915 Positive_regulation of Agt 27 0.56 12.97 1.96
71 INT12801 Negative_regulation of Regulation of Agt 4 0.43 1.2 1.96
72 INT43944 Negative_regulation of Positive_regulation of Agt 4 0.42 1.44 1.93
73 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92
74 INT76834 Negative_regulation of Gene_expression of Edn1 4 0.43 1.76 1.88
75 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79
76 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76
77 INT15980 Positive_regulation of Positive_regulation of Agt 6 0.50 2.99 1.76
78 INT173700 Negative_regulation of Binding of Edn1 2 0.58 0.41 1.76
79 INT3152 Transcription of Agt 7 0.72 5.09 1.68
80 INT14842 Negative_regulation of Binding of EDN1 4 0.57 0.67 1.66
81 INT72021 Localization of Ednra 7 0.58 3.13 1.53
82 INT181579 Phosphorylation of Edn1 1 0.71 8.59 1.51
83 INT15407 Positive_regulation of Positive_regulation of Edn1 5 0.62 3.69 1.49
84 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48
85 INT65640 Positive_regulation of Localization of Edn1 2 0.42 2.16 1.48
86 INT23938 Positive_regulation of Gene_expression of EDNRA 8 0.45 9.82 1.47
87 INT129488 Regulation of Gene_expression of EDNRA 5 0.51 3.39 1.44
88 INT34768 Negative_regulation of Negative_regulation of AGT 10 0.25 2.79 1.42
89 INT8067 Negative_regulation of Binding of AGT 12 0.25 10.33 1.39
90 INT239215 Binding of Agt 9 0.38 6.75 1.35
91 INT11306 Regulation of Gene_expression of Agt 7 0.45 3.29 1.31
92 INT11241 Transcription of AGT 4 0.52 1.83 1.27
93 INT19319 Negative_regulation of Binding of Agt 9 0.42 3.42 1.24
94 INT79916 Negative_regulation of Agt 14 0.47 6 1.22
95 INT47644 Positive_regulation of Localization of AGT 4 0.45 1.24 1.2
96 INT17802 Transcription of Edn1 6 0.24 6.31 1.18
97 INT28594 Positive_regulation of Transcription of Agt 2 0.47 1.3 1.15
98 INT115621 Positive_regulation of Binding of AGT 1 0.02 0 1.15
99 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12
100 INT61123 Localization of Edn2 1 0.55 0.27 1.05
101 INT69803 Regulation of Localization of Edn1 3 0.62 0.79 0.98
102 INT72024 Localization of EDNRA 11 0.57 8.22 0.96
103 INT76835 Negative_regulation of Gene_expression of Ednra 2 0.10 0.89 0.96
104 INT49255 Protein_catabolism of EDN1 5 0.99 2.66 0.95
105 INT69422 Positive_regulation of Negative_regulation of EDN1 2 0.43 0.96 0.95
106 INT49254 Transcription of EDN1 5 0.69 2.42 0.94
107 INT152081 Phosphorylation of Edn1 1 0.53 0.39 0.9
108 INT178133 Negative_regulation of Positive_regulation of EDNRA 2 0.35 2.18 0.88
109 INT61591 Negative_regulation of Localization of EDN1 11 0.59 2.09 0.85
110 INT230806 Positive_regulation of Gene_expression of Agt 11 0.55 16.08 0.83
111 INT6243 Regulation of Edn3 2 0.35 0.2 0.83
112 INT57433 Positive_regulation of Binding of EDN1 3 0.49 0.62 0.82
113 INT186579 Positive_regulation of Gene_expression of Ednra 5 0.07 0.89 0.76
114 INT186681 Gene_expression of Edn2 2 0.09 1.01 0.76
115 INT21943 Positive_regulation of Positive_regulation of AGT 6 0.46 3.29 0.75
116 INT34715 Regulation of Regulation of AGT 2 0.37 0.96 0.75
117 INT61122 Regulation of Regulation of Edn3 1 0.35 0.2 0.75
118 INT61121 Regulation of Regulation of Edn1 1 0.43 0.2 0.75
119 INT8614 Negative_regulation of Edn2 3 0.06 0.07 0.73
120 INT59970 Positive_regulation of Binding of Edn1 2 0.40 1.11 0.71
121 INT148074 Regulation of Agt 9 0.49 5.42 0.7
122 INT38735 Protein_catabolism of Agt 7 0.99 2.79 0.7
123 INT160461 Phosphorylation of Agt 1 0.31 0.4 0.7
124 INT63556 Binding of Edn3 1 0.24 0.63 0.7
125 INT160463 Positive_regulation of Phosphorylation of Agt 1 0.19 0.41 0.7
126 INT313697 Phosphorylation of Ednra 1 0.18 0 0.7
127 INT21957 Negative_regulation of Negative_regulation of Edn1 5 0.43 1.34 0.69
128 INT34769 Regulation of Gene_expression of AGT 3 0.19 1.39 0.67
129 INT49252 Positive_regulation of Localization of EDN1 17 0.69 6.55 0.66
130 INT100396 Transcription of Edn1 7 0.69 2.48 0.66
131 INT50061 Negative_regulation of Edn3 4 0.58 0.77 0.65
132 INT49256 Regulation of Positive_regulation of EDN1 2 0.45 2.5 0.65
133 INT7153 Positive_regulation of Regulation of Edn1 2 0.35 1.97 0.57
134 INT135715 Negative_regulation of Localization of Edn1 5 0.42 1.7 0.56
135 INT63910 Regulation of Positive_regulation of Edn1 2 0.43 0.64 0.54
136 INT40021 Regulation of Binding of Agt 4 0.59 1.53 0.53
137 INT32618 Regulation of Positive_regulation of Agt 2 0.43 0.42 0.52
138 INT131641 Negative_regulation of Negative_regulation of Edn1 1 0.37 0.31 0.52
139 INT186686 Regulation of Positive_regulation of EDNRA 5 0.22 2.35 0.51
140 INT181581 Regulation of Positive_regulation of Edn1 4 0.23 3.76 0.51
141 INT126442 Negative_regulation of Gene_expression of Ednra 3 0.33 1.94 0.51
142 INT8663 Positive_regulation of EDN2 3 0.38 0.65 0.5
143 INT47645 Negative_regulation of Localization of AGT 2 0.11 1.09 0.49
144 INT115202 Positive_regulation of Positive_regulation of Ednra 2 0.39 2.88 0.49
145 INT120405 Phosphorylation of EDNRA 1 0.61 0.38 0.48
146 INT55372 Regulation of Localization of Edn1 2 0.38 0.64 0.46
147 INT99588 Positive_regulation of Binding of Agt 2 0.69 0.23 0.45
148 INT55370 Positive_regulation of Localization of Edn3 2 0.47 1.13 0.44
149 INT14039 Regulation of Regulation of Agt 1 0.30 0 0.44
150 INT57434 Regulation of Regulation of EDN1 1 0.40 0.47 0.44
151 INT324888 Transcription of Ednra 2 0.13 0.66 0.43
152 INT33017 Negative_regulation of Protein_catabolism of AGT 3 0.37 0 0.42
153 INT158057 Positive_regulation of Positive_regulation of EDNRA 2 0.15 0 0.41
154 INT81433 Negative_regulation of Positive_regulation of Edn1 4 0.39 0.81 0.38
155 INT168066 Transcription of Edn3 1 0.38 0.87 0.38
156 INT8664 Positive_regulation of EDN3 2 0.38 0 0.37
157 INT129487 Negative_regulation of EDN3 1 0.38 0.35 0.35
158 INT113368 Regulation of Negative_regulation of Edn1 1 0.45 0.71 0.35
159 INT95605 Regulation of Binding of AGT 3 0.44 0.2 0.34
160 INT141013 Regulation of Gene_expression of Edn1 2 0.24 0.55 0.34
161 INT27928 Phosphorylation of AGT 1 0.52 0.15 0.34
162 INT27929 Negative_regulation of Phosphorylation of AGT 1 0.27 0.15 0.34
163 INT16368 Protein_catabolism of Edn1 2 0.72 0.18 0.31
164 INT131110 Localization of EDN3 1 0.03 0.74 0.31
165 INT131109 Positive_regulation of Localization of EDN3 1 0.02 0.76 0.31
166 INT4636 Positive_regulation of Regulation of Agt 4 0.50 1.3 0.3
167 INT72022 Positive_regulation of Localization of Ednra 2 0.32 0.07 0.3
168 INT43398 Regulation of Localization of Agt 1 0.28 0 0.3
169 INT350970 Negative_regulation of Binding of EDNRA 1 0.41 0.86 0.29
170 INT334747 Regulation of Binding of Ednra 1 0.06 0.05 0.28
171 INT3331 Positive_regulation of Protein_catabolism of AGT 1 0.33 0 0.27
172 INT84038 Protein_catabolism of Edn1 2 0.86 0.69 0.26
173 INT164617 Protein_catabolism of Agt 2 0.79 5.3 0.25
174 INT239213 Localization of Agt 6 0.64 3.26 0.22
175 INT8660 Positive_regulation of Positive_regulation of EDN2 2 0.38 0.23 0.22
176 INT8665 Positive_regulation of Positive_regulation of EDN3 1 0.38 0 0.22
177 INT67265 Positive_regulation of Negative_regulation of Edn1 1 0.61 0.05 0.21
178 INT230802 Positive_regulation of Positive_regulation of Agt 2 0.40 0.41 0.2
179 INT334746 Positive_regulation of Localization of Ednra 1 0.07 0 0.2
180 INT156920 Phosphorylation of EDN1 4 0.61 0.66 0.19
181 INT53372 Positive_regulation of Regulation of Edn1 1 0.50 0 0.19
182 INT100397 Regulation of Transcription of Edn1 1 0.00 0.1 0.19
183 INT324881 Regulation of Transcription of Ednra 1 0.08 0.66 0.19
184 INT72023 Positive_regulation of Localization of EDNRA 1 0.02 0.07 0.18
185 INT72025 Negative_regulation of Localization of EDNRA 1 0.01 0.07 0.18
186 INT72020 Negative_regulation of Localization of Ednra 1 0.24 0.07 0.18
187 INT1770 Positive_regulation of Negative_regulation of Agt 2 0.49 1.09 0.17
188 INT173335 Negative_regulation of Gene_expression of EDNRA 2 0.19 0.71 0.17
189 INT256015 Negative_regulation of Regulation of Agt 1 0.18 0.16 0.17
190 INT26353 Binding of Edn2 1 0.01 0 0.17
191 INT79914 Positive_regulation of Negative_regulation of Agt 1 0.50 0.19 0.17
192 INT55371 Positive_regulation of Edn3 1 0.69 0.38 0.14
193 INT256004 Negative_regulation of Gene_expression of Agt 2 0.34 8.07 0.13
194 INT239214 Positive_regulation of Localization of Agt 2 0.55 1.89 0.13
195 INT323040 Gene_expression of EDN2 1 0.32 0.13 0.13
196 INT284152 Regulation of Transcription of EDN1 1 0.32 0.44 0.13
197 INT119156 Positive_regulation of Protein_catabolism of Agt 1 0.49 0 0.13
198 INT214619 Positive_regulation of Negative_regulation of AGT 1 0.04 0.98 0.13
199 INT6362 Negative_regulation of Localization of Edn1 3 0.16 1.92 0.12
200 INT70908 Transcription of EDNRA 1 0.08 0.33 0.12
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